| Wednesday, April 4 |
| » Major-league debuts: Mark Clear (Angels) |
| Friday, April 6 |
| » Lost to Twins (1-0), 5-3 | Oakland-Alameda County Stadium (0-1) | 0-1 | |
| » W: Dave Goltz (1-0) L: Rick Langford (0-1) S: Mike Marshall (1) | Fourth | 1½ out |
| » Major-league debuts: John Castino and Rick Sofield (Twins) |
| Saturday, April 7 |
| » Lost to Twins (2-0), 3-1 | Oakland-Alameda County Stadium (0-2) | 0-2 | Lost 2 |
| » W: Mike Marshall (1-0) L: Jim Todd (0-1) | Fifth | 2 out |
| Sunday, April 8 |
| » Lost to Twins (3-0), 3-1 | Oakland-Alameda County Stadium (0-3) | 0-3 | Lost 3 |
| » W: Geoff Zahn (1-0) L: Mike Norris (0-1) | Fifth | 3 out |
| Monday, April 9 |
| » Lost to Mariners (3-2), 5-2 | Kingdome (0-1) | 0-4 | Lost 4 |
| » W: Floyd Bannister (1-0) L: John Henry Johnson (0-1) S: Shane Rawley (1) | Seventh | 3½ out |
| Tuesday, April 10 |
| » Lost to Mariners (4-2), 4-1 | Kingdome (0-2) | 0-5 | Lost 5 |
| » W: Glenn Abbott (1-0) L: Rick Langford (0-2) S: Shane Rawley (2) | Seventh | 4½ out |
| Wednesday, April 11 |
| » Defeated Mariners (4-3), 14-7 | Kingdome (1-2) | 1-5 | |
| » W: Jim Todd (1-1) L: Rick Honeycutt (0-2) | Sixth | 3½ out |
| Thursday, April 12 |
| » Lost to Mariners (5-3), 4-3 | Kingdome (1-3) | 1-6 | |
| » W: John Montague (2-0) L: Bob Lacey (0-1) | Seventh | 4½ out |
| Friday, April 13 |
| » Lost to Angels (5-3), 10-1 | Oakland-Alameda County Stadium (0-4) | 1-7 | Lost 2 |
| » W: Don Aase (1-0) L: John Henry Johnson (0-2) | Seventh | 5½ out |
| Saturday, April 14 |
| » Lost to Angels (6-3), 9-3 | Oakland-Alameda County Stadium (0-5) | 1-8 | Lost 3 |
| » W: Dave Frost (1-0) L: Rick Langford (0-3) | Seventh | 6½ out |
| Sunday, April 15 |
| » Lost to Angels (7-3), 8-1 | Oakland-Alameda County Stadium (0-6) | 1-9 | Lost 4 |
| » W: Frank Tanana (1-2) L: Matt Keough (0-1) | Seventh | 6½ out |
| Monday, April 16 |
| » Defeated Mariners (5-7), 4-2 | Oakland-Alameda County Stadium (1-6) | 2-9 | |
| » W: Mike Norris (1-1) L: Shane Rawley (0-2) S: Bob Lacey (1) | Seventh | 6 out |
| Tuesday, April 17 |
| » Defeated Mariners (5-8), 6-5 | Oakland-Alameda County Stadium (2-6) | 3-9 | Won 2 |
| » W: Dave Heaverlo (1-0) L: Odell Jones (0-1) | Seventh | 6 out |
| Wednesday, April 18 |
| » Defeated Mariners (5-9), 5-2 | Oakland-Alameda County Stadium (3-6) | 4-9 | Won 3 |
| » W: Alan Wirth (1-0) L: Rick Honeycutt (0-3) S: Dave Heaverlo (1) | Seventh | 5 out |
| Friday, April 20 |
| » Lost to Angels (11-3), 7-4 | Anaheim Stadium (0-1) | 4-10 | |
| » W: Frank Tanana (2-2) L: Rick Langford (0-4) S: Dave Frost (1) | Seventh | 7 out |
| Saturday, April 21 |
| » Lost to Angels (12-3), 13-1 | Anaheim Stadium (0-2) | 4-11 | Lost 2 |
| » W: Nolan Ryan (3-1) L: Matt Keough (0-2) | Seventh | 8 out |
| Sunday, April 22 |
| » Defeated Angels (12-4), 7-6 | Anaheim Stadium (1-2) | 5-11 | |
| » W: Dave Heaverlo (2-0) L: Dave LaRoche (1-1) | Sixth | 7 out |
| Tuesday, April 24 |
| » Lost to Yankees (10-6), 3-1 | Oakland-Alameda County Stadium (3-7) | 5-12 | |
| » W: Tommy John (4-0) L: John Henry Johnson (0-3) | Sixth | 7 out |
| Wednesday, April 25 |
| » Defeated Yankees (10-7), 1-0 | Oakland-Alameda County Stadium (4-7) | 6-12 | |
| » W: Craig Minetto (1-0) L: Ed Figueroa (2-2) S: Jim Todd (1) | Sixth | 6 out |
| Friday, April 27 |
| » Lost to Orioles (12-8), 7-1 | Oakland-Alameda County Stadium (4-8) | 6-13 | |
| » W: Mike Flanagan (3-2) L: Matt Keough (0-3) | Sixth | 6½ out |
| Saturday, April 28 |
| » Defeated Orioles (12-9), 8-5 | Oakland-Alameda County Stadium (5-8) | 7-13 | |
| » W: Jim Todd (2-1) L: Scott McGregor (0-1) S: Dave Heaverlo (2) | Sixth | 6½ out |
| Sunday, April 29 |
| » Lost to Orioles (13-9), 13-1 | Oakland-Alameda County Stadium (5-9) | 7-14 | |
| » W: Tippy Martinez (1-0) L: John Henry Johnson (0-4) | Seventh | 6½ out |
| Monday, April 30 |
| » Defeated Red Sox (13-7), 5-4 | Oakland-Alameda County Stadium (6-9) | 8-14 | |
| » W: Bob Lacey (1-1) L: Dick Drago (3-1) | Sixth | 6½ out |
| Tuesday, May 1 |
| » Defeated Red Sox (13-8), 7-5 | Oakland-Alameda County Stadium (7-9) | 9-14 | Won 2 |
| » W: Steve McCatty (1-0) L: Bob Stanley (2-2) S: Bob Lacey (2) | Sixth | 6 out |
| Wednesday, May 2 |
| » Lost to Red Sox (14-8), 2-1 | Oakland-Alameda County Stadium (7-10) | 9-15 | |
| » W: Mike Torrez (2-1) L: Matt Keough (0-4) | Sixth | 7 out |
| Thursday, May 3 |
| Former Athletic Tom Jenkins dies in Weymouth, MA at the age of 82. |
| Friday, May 4 |
| » Defeated Yankees (11-13), 11-5 | Yankee Stadium (1-0) | 10-15 | |
| » W: Mike Norris (2-1) L: Jim Beattie (0-1) S: Bob Lacey (3) | Sixth | 7½ out |
| Saturday, May 5 |
| » Lost to Yankees (12-13), 5-4 | Yankee Stadium (1-1) | 10-16 | |
| » W: Tommy John (6-0) L: Dave Heaverlo (2-1) | Sixth | 7½ out |
| Sunday, May 6 |
| » Lost to Yankees (13-13), 6-5 | Yankee Stadium (1-2) | 10-17 | Lost 2 |
| » W: Ron Guidry (3-2) L: Dave Heaverlo (2-2) | Sixth | 8½ out |
| Monday, May 7 |
| » Defeated Orioles (18-10), 5-3 | Memorial Stadium (1-0) | 11-17 | |
| » W: Rick Langford (1-4) L: Tippy Martinez (1-1) | Sixth | 8½ out |
| Tuesday, May 8 |
| » Lost to Orioles (19-10), 8-2 | Memorial Stadium (1-1) | 11-18 | |
| » W: Mike Flanagan (5-2) L: Jim Todd (2-2) | Sixth | 9½ out |
| Wednesday, May 9 |
| » Defeated Orioles (19-11), 4-2 | Memorial Stadium (2-1) | 12-18 | |
| » W: Mike Norris (3-1) L: Jim Palmer (4-2) | Sixth | 9 out |
| Thursday, May 10 |
| » Lost to Orioles (20-11), 3-1 | Memorial Stadium (2-2) | 12-19 | |
| » W: Dennis Martinez (4-2) L: John Henry Johnson (0-5) | Sixth | 9½ out |
| Friday, May 11 |
| » Lost to Red Sox (19-11), 11-2 | Fenway Park (0-1) | 12-20 | Lost 2 |
| » W: Bob Stanley (3-2) L: Matt Keough (0-5) | Sixth | 10½ out |
| Saturday, May 12 |
| » Lost to Red Sox (20-11), 8-2 | Fenway Park (0-2) | 12-21 | Lost 3 |
| » W: Mike Torrez (4-1) L: Rick Langford (1-5) | Sixth | 11½ out |
| Sunday, May 13 |
| » Lost to Red Sox (21-11), 8-2 | Fenway Park (0-3) | 12-22 | Lost 4 |
| » W: Chuck Rainey (2-2) L: Mike Norris (3-2) | Sixth | 11½ out |
| Tuesday, May 15 |
| » Lost to White Sox (16-17), 2-1 | Oakland-Alameda County Stadium (7-11) | 12-23 | Lost 5 |
| » W: Ross Baumgarten (4-0) L: John Henry Johnson (0-6) S: Mike Proly (7) | Sixth | 11 out |
| Wednesday, May 16 |
| » Lost to White Sox (17-17), 3-1 | Oakland-Alameda County Stadium (7-12) | 12-24 | Lost 6 |
| » W: Francisco Barrios (4-1) L: Matt Keough (0-6) S: Steve Trout (1) | Sixth | 11 out |
| Thursday, May 17 |
| » Lost to White Sox (18-17), 5-1 | Oakland-Alameda County Stadium (7-13) | 12-25 | Lost 7 |
| » W: Ken Kravec (3-3) L: Rick Langford (1-6) | Sixth | 12 out |
| Friday, May 18 |
| » Lost to Brewers (21-17), 8-0 | Oakland-Alameda County Stadium (7-14) | 12-26 | Lost 8 |
| » W: Bill Travers (2-2) L: Mike Norris (3-3) | Sixth | 13 out |
| Saturday, May 19 |
| » Defeated Brewers (21-18), 12-4 | Oakland-Alameda County Stadium (8-14) | 13-26 | |
| » W: John Henry Johnson (1-6) L: Moose Haas (2-3) | Sixth | 12½ out |
| Sunday, May 20 |
| » Defeated Brewers (21-19), 7-6 | Oakland-Alameda County Stadium (9-14) | 14-26 | Won 2 |
| » W: Dave Hamilton (1-0) L: Jerry Augustine (1-2) | Sixth | 11 out |
| » Defeated Brewers (21-20), 2-1 | Oakland-Alameda County Stadium (10-14) | 15-26 | Won 3 |
| » W: Steve McCatty (2-0) L: Jim Slaton (3-3) S: Dave Heaverlo (3) | Sixth | 11 out |
| Tuesday, May 22 |
| » Lost to White Sox (19-20), 5-4 | Comiskey Park I (0-1) | 15-27 | |
| » W: Rich Hinton (1-1) L: Dave Heaverlo (2-3) | Sixth | 11½ out |
| Wednesday, May 23 |
| » Lost to White Sox (20-20), 6-1 | Comiskey Park I (0-2) | 15-28 | Lost 2 |
| » W: Ken Kravec (4-3) L: John Henry Johnson (1-7) | Sixth | 11½ out |
| Thursday, May 24 |
| » Lost to White Sox (21-20), 10-1 | Comiskey Park I (0-3) | 15-29 | Lost 3 |
| » W: Rich Wortham (5-4) L: Matt Keough (0-7) | Sixth | 12 out |
| Friday, May 25 |
| » Lost to Brewers (25-20), 3-2 | County Stadium (0-1) | 15-30 | Lost 4 |
| » W: Mike Caldwell (5-4) L: Bob Lacey (1-2) | Seventh | 12 out |
| Saturday, May 26 |
| » Lost to Brewers (26-20), 8-4 | County Stadium (0-2) | 15-31 | Lost 5 |
| » W: Jim Slaton (4-3) L: Rick Langford (1-7) | Seventh | 12 out |
| Sunday, May 27 |
| » Defeated Brewers (26-21), 2-1 | County Stadium (1-2) | 16-31 | |
| » W: Steve McCatty (3-0) L: Lary Sorensen (6-5) S: Dave Heaverlo (4) | Seventh | 12 out |
| Monday, May 28 |
| » Lost to Twins (26-18), 10-7 | Metropolitan Stadium (0-1) | 16-32 | |
| » W: Mike Marshall (8-4) L: Dave Heaverlo (2-4) | Seventh | 12½ out |
| Wednesday, May 30 |
| » Defeated Twins (26-19), 5-4 | Metropolitan Stadium (1-1) | 17-32 | |
| » W: John Henry Johnson (2-7) L: Roger Erickson (0-5) S: Bob Lacey (4) | Sixth | 13 out |
| Thursday, May 31 |
| » Lost to Twins (27-19), 13-2 | Metropolitan Stadium (1-2) | 17-33 | |
| » W: Paul Hartzell (2-3) L: Rick Langford (1-8) | Seventh | 13 out |
| Friday, June 1 |
| » Defeated Tigers (22-22), 3-2 | Oakland-Alameda County Stadium (11-14) | 18-33 | |
| » W: Steve McCatty (4-0) L: John Hiller (3-4) | Seventh | 12 out |
| Saturday, June 2 |
| » Lost to Tigers (23-22), 9-3 | Oakland-Alameda County Stadium (11-15) | 18-34 | |
| » W: Jack Morris (3-1) L: Craig Minetto (1-1) S: Dave Tobik (1) | Seventh | 13 out |
| Sunday, June 3 |
| » Lost to Tigers (24-22), 2-0 | Oakland-Alameda County Stadium (11-16) | 18-35 | Lost 2 |
| » W: Dave Rozema (3-2) L: John Henry Johnson (2-8) | Seventh | 13 out |
| Monday, June 4 |
| » Lost to Indians (24-27), 5-4 | Oakland-Alameda County Stadium (11-17) | 18-36 | Lost 3 |
| » W: Sid Monge (3-5) L: Bob Lacey (1-3) | Seventh | 14 out |
| Tuesday, June 5 |
| » Lost to Indians (25-27), 12-3 | Oakland-Alameda County Stadium (11-18) | 18-37 | Lost 4 |
| » W: Rick Waits (8-3) L: Rick Langford (1-9) | Seventh | 15 out |
| Wednesday, June 6 |
| » Lost to Indians (26-27), 6-4 | Oakland-Alameda County Stadium (11-19) | 18-38 | Lost 5 |
| » W: Rick Wise (6-5) L: Dave Heaverlo (2-5) S: Victor Cruz (5) | Seventh | 15 out |
| Friday, June 8 |
| » Lost to Blue Jays (15-42), 2-1 | Oakland-Alameda County Stadium (11-20) | 18-39 | Lost 6 |
| » W: Tom Buskey (2-1) L: Dave Heaverlo (2-6) | Seventh | 16 out |
| Saturday, June 9 |
| » Lost to Blue Jays (16-42), 5-0 | Oakland-Alameda County Stadium (11-21) | 18-40 | Lost 7 |
| » W: Phil Huffman (3-6) L: Matt Keough (0-8) | Seventh | 17 out |
| Sunday, June 10 |
| » Defeated Blue Jays (16-43), 12-1 | Oakland-Alameda County Stadium (12-21) | 19-40 | |
| » W: Dave Hamilton (2-0) L: Tom Underwood (0-9) | Seventh | 16 out |
| Monday, June 11 |
| » Lost to Tigers (27-26), 3-1 | Tiger Stadium (0-1) | 19-41 | |
| » W: Jack Morris (4-2) L: Steve McCatty (4-1) | Seventh | 17 out |
| Tuesday, June 12 |
| » Lost to Tigers (28-26), 9-2 | Tiger Stadium (0-2) | 19-42 | Lost 2 |
| » W: Pat Underwood (2-0) L: Craig Minetto (1-2) | Seventh | 17 out |
| Wednesday, June 13 |
| » Lost to Indians (29-30), 6-4 | Cleveland Stadium (0-1) | 19-43 | Lost 3 |
| » W: Wayne Garland (3-7) L: Bob Lacey (1-4) | Seventh | 17½ out |
| Thursday, June 14 |
| » Lost to Indians (30-30), 2-1 | Cleveland Stadium (0-2) | 19-44 | Lost 4 |
| » W: Sid Monge (5-5) L: Jim Todd (2-3) | Seventh | 18½ out |
| Friday, June 15 |
| » Lost to Blue Jays (19-46), 6-0 | Exhibition Stadium (0-1) | 19-45 | Lost 5 |
| » W: Tom Underwood (1-9) L: Dave Hamilton (2-1) | Seventh | 19½ out |
| Saturday, June 16 |
| » Lost to Blue Jays (20-46), 3-2 | Exhibition Stadium (0-2) | 19-46 | Lost 6 |
| » W: Dave Lemanczyk (7-3) L: Steve McCatty (4-2) | Seventh | 20½ out |
| Sunday, June 17 |
| » Lost to Blue Jays (21-46), 10-9 | Exhibition Stadium (0-3) | 19-47 | Lost 7 |
| » W: Tom Buskey (3-1) L: Dave Heaverlo (2-7) | Seventh | 20½ out |
| Monday, June 18 |
| » Lost to Royals (35-31), 3-2 | Oakland-Alameda County Stadium (12-22) | 19-48 | Lost 8 |
| » W: Larry Gura (4-6) L: Mike Norris (3-4) S: Al Hrabosky (8) | Seventh | 21½ out |
| Tuesday, June 19 |
| » Defeated Royals (35-32), 6-5 | Oakland-Alameda County Stadium (13-22) | 20-48 | |
| » W: Dave Heaverlo (3-7) L: Al Hrabosky (4-3) | Seventh | 20½ out |
| Wednesday, June 20 |
| » Lost to Royals (36-32), 9-2 | Oakland-Alameda County Stadium (13-23) | 20-49 | |
| » W: Paul Splittorff (9-5) L: Dave Hamilton (2-2) | Seventh | 21½ out |
| Thursday, June 21 |
| » Defeated Royals (36-33), 10-7 | Oakland-Alameda County Stadium (14-23) | 21-49 | |
| » W: Steve McCatty (5-2) L: Steve Busby (2-5) S: Dave Heaverlo (5) | Seventh | 20½ out |
| Friday, June 22 |
| » Defeated Rangers (36-33), 6-5 | Oakland-Alameda County Stadium (15-23) | 22-49 | Won 2 |
| » W: Rick Langford (2-9) L: Steve Comer (6-6) S: Dave Heaverlo (6) | Seventh | 19½ out |
| Saturday, June 23 |
| » Lost to Rangers (37-33), 8-5 | Oakland-Alameda County Stadium (15-24) | 22-50 | |
| » W: Jim Kern (9-1) L: Bob Lacey (1-5) | Seventh | 19½ out |
| Sunday, June 24 |
| » Lost to Rangers (38-33), 5-1 | Oakland-Alameda County Stadium (15-25) | 22-51 | Lost 2 |
| » W: John Henry Johnson (4-8) L: Matt Keough (0-9) | Sixth | 20 out |
| » Lost to Rangers (39-33), 7-2 | Oakland-Alameda County Stadium (15-26) | 22-52 | Lost 3 |
| » W: Doc Medich (1-2) L: Dave Hamilton (2-3) S: Jim Kern (11) | Sixth | 20 out |
| » Major-league debuts: Rickey Henderson (Athletics) |
| Tuesday, June 26 |
| » Lost to Royals (40-33), 7-6 | Royals Stadium (0-1) | 22-53 | Lost 4 |
| » W: Al Hrabosky (5-3) L: Jim Todd (2-4) | Sixth | 20 out |
| Wednesday, June 27 |
| » Lost to Royals (41-33), 10-3 | Royals Stadium (0-2) | 22-54 | Lost 5 |
| » W: Steve Busby (3-5) L: Mike Morgan (0-1) | Sixth | 20 out |
| Thursday, June 28 |
| » Lost to Royals (42-33), 7-6 | Royals Stadium (0-3) | 22-55 | Lost 6 |
| » W: Al Hrabosky (6-3) L: Dave Heaverlo (3-8) | Sixth | 21 out |
| Friday, June 29 |
| » Lost to Rangers (43-33), 5-3 | Arlington Stadium (0-1) | 22-56 | Lost 7 |
| » W: Danny Darwin (1-0) L: Matt Keough (0-10) S: Sparky Lyle (8) | Seventh | 22 out |
| Saturday, June 30 |
| » Lost to Rangers (44-33), 4-3 | Arlington Stadium (0-2) | 22-57 | Lost 8 |
| » W: Jim Kern (10-1) L: Jim Todd (2-5) | Seventh | 23 out |
| Sunday, July 1 |
| » Defeated Rangers (44-34), 13-12 | Arlington Stadium (1-2) | 23-57 | |
| » W: Rick Langford (3-9) L: Doc Medich (1-3) S: Jim Todd (2) | Seventh | 22 out |
| Monday, July 2 |
| » Lost to Angels (46-35), 8-3 | Anaheim Stadium (1-3) | 23-58 | |
| » W: Jim Barr (4-4) L: Mike Morgan (0-2) | Seventh | 23 out |
| Tuesday, July 3 |
| » Lost to Angels (47-35), 3-0 | Anaheim Stadium (1-4) | 23-59 | Lost 2 |
| » W: Dave Frost (6-4) L: Brian Kingman (0-1) | Seventh | 24 out |
| Wednesday, July 4 |
| » Lost to Angels (48-35), 17-6 | Anaheim Stadium (1-5) | 23-60 | Lost 3 |
| » W: Mark Clear (9-2) L: Dave Heaverlo (3-9) | Seventh | 25 out |
| Thursday, July 5 |
| » Defeated Angels (48-36), 3-0 | Anaheim Stadium (2-5) | 24-60 | |
| » W: Rick Langford (4-9) L: Nolan Ryan (10-6) | Seventh | 24½ out |
| Friday, July 6 |
| » Lost to Yankees (45-38), 4-3 | Oakland-Alameda County Stadium (15-27) | 24-61 | |
| » W: Ron Davis (8-0) L: Steve McCatty (5-3) | Seventh | 25½ out |
| » Lost to Yankees (46-38), 3-0 | Oakland-Alameda County Stadium (15-28) | 24-62 | Lost 2 |
| » W: Tommy John (13-3) L: Dave Hamilton (2-4) | Seventh | 25½ out |
| Saturday, July 7 |
| » Lost to Yankees (47-38), 8-3 | Oakland-Alameda County Stadium (15-29) | 24-63 | Lost 3 |
| » W: Don Hood (3-0) L: Mike Morgan (0-3) S: Ken Clay (2) | Seventh | 26½ out |
| Sunday, July 8 |
| » Lost to Yankees (48-38), 2-0 | Oakland-Alameda County Stadium (15-30) | 24-64 | Lost 4 |
| » W: Luis Tiant (6-3) L: Brian Kingman (0-2) | Seventh | 27 out |
| Monday, July 9 |
| » Lost to Orioles (56-29), 7-3 | Oakland-Alameda County Stadium (15-31) | 24-65 | Lost 5 |
| » W: Mike Flanagan (11-6) L: Matt Keough (0-11) S: Don Stanhouse (12) | Seventh | 27½ out |
| Tuesday, July 10 |
| » Defeated Orioles (56-30), 7-6 | Oakland-Alameda County Stadium (16-31) | 25-65 | |
| » W: Rick Langford (5-9) L: Sammy Stewart (5-3) S: Dave Heaverlo (7) | Seventh | 27½ out |
| Wednesday, July 11 |
| » Lost to Orioles (57-30), 3-1 | Oakland-Alameda County Stadium (16-32) | 25-66 | |
| » W: Dennis Martinez (11-6) L: Steve McCatty (5-4) | Seventh | 27½ out |
| Friday, July 13 |
| » Lost to Red Sox (54-32), 2-0 | Oakland-Alameda County Stadium (16-33) | 25-67 | Lost 2 |
| » W: Steve Renko (8-3) L: Mike Morgan (0-4) S: Bill Campbell (7) | Seventh | 28½ out |
| Saturday, July 14 |
| » Lost to Red Sox (55-32), 8-7 | Oakland-Alameda County Stadium (16-34) | 25-68 | Lost 3 |
| » W: Allen Ripley (1-0) L: Steve McCatty (5-5) S: Bill Campbell (8) | Seventh | 29½ out |
| Sunday, July 15 |
| » Lost to Red Sox (56-32), 3-2 | Oakland-Alameda County Stadium (16-35) | 25-69 | Lost 4 |
| » W: Bob Stanley (11-6) L: Rick Langford (5-10) | Seventh | 30½ out |
| Thursday, July 19 |
| » Lost to Yankees (50-43), 10-2 | Yankee Stadium (1-3) | 25-70 | Lost 5 |
| » W: Luis Tiant (7-4) L: Mike Morgan (0-5) | Seventh | 31 out |
| Friday, July 20 |
| » Defeated Yankees (50-44), 5-1 | Yankee Stadium (2-3) | 26-70 | |
| » W: Brian Kingman (1-2) L: Tommy John (13-5) S: Dave Hamilton (1) | Seventh | 30 out |
| Saturday, July 21 |
| » Lost to Yankees (51-44), 12-4 | Yankee Stadium (2-4) | 26-71 | |
| » W: Ron Guidry (7-7) L: Craig Minetto (1-3) | Seventh | 30 out |
| Sunday, July 22 |
| » Lost to Orioles (63-32), 4-1 | Memorial Stadium (2-3) | 26-72 | Lost 2 |
| » W: Steve Stone (7-7) L: Rick Langford (5-11) | Seventh | 30 out |
| Former Athletic Amos Strunk dies in Llanerch, PA at the age of 91. |
| Monday, July 23 |
| » Lost to Orioles (64-32), 7-4 | Memorial Stadium (2-4) | 26-73 | Lost 3 |
| » W: Tippy Martinez (6-1) L: Matt Keough (0-12) | Seventh | 31 out |
| Tuesday, July 24 |
| » Lost to Red Sox (59-35), 7-3 | Fenway Park (0-4) | 26-74 | Lost 4 |
| » W: Dennis Eckersley (11-5) L: Mike Morgan (0-6) | Seventh | 31 out |
| Wednesday, July 25 |
| » Lost to Red Sox (60-35), 16-4 | Fenway Park (0-5) | 26-75 | Lost 5 |
| » W: Mike Torrez (10-6) L: Brian Kingman (1-3) | Seventh | 32 out |
| Thursday, July 26 |
| » Defeated Red Sox (60-36), 8-6 | Fenway Park (1-5) | 27-75 | |
| » W: Steve McCatty (6-5) L: Steve Renko (8-5) S: Dave Heaverlo (8) | Seventh | 31 out |
| Friday, July 27 |
| » Lost to Mariners (44-60), 1-0 | Oakland-Alameda County Stadium (16-36) | 27-76 | |
| » W: Rick Honeycutt (7-7) L: Rick Langford (5-12) S: Byron McLaughlin (9) | Seventh | 31 out |
| Saturday, July 28 |
| » Defeated Mariners (44-61), 6-5 | Oakland-Alameda County Stadium (17-36) | 28-76 | |
| » W: Dave Hamilton (3-4) L: Odell Jones (3-10) | Seventh | 31 out |
| Sunday, July 29 |
| » Defeated Mariners (44-62), 2-1 | Oakland-Alameda County Stadium (18-36) | 29-76 | Won 2 |
| » W: Mike Morgan (1-6) L: Floyd Bannister (5-10) | Seventh | 31 out |
| Monday, July 30 |
| » Lost to Twins (55-47), 3-0 | Oakland-Alameda County Stadium (18-37) | 29-77 | |
| » W: Dave Goltz (10-7) L: Brian Kingman (1-4) | Seventh | 31 out |
| Tuesday, July 31 |
| » Defeated Twins (55-48), 2-1 | Oakland-Alameda County Stadium (19-37) | 30-77 | |
| » W: Steve McCatty (7-5) L: Geoff Zahn (9-3) | Seventh | 31 out |
| Wednesday, August 1 |
| » Defeated Twins (55-49), 7-1 | Oakland-Alameda County Stadium (20-37) | 31-77 | Won 2 |
| » W: Rick Langford (6-12) L: Paul Hartzell (5-7) | Seventh | 30 out |
| Friday, August 3 |
| » Lost to Mariners (47-63), 1-0 | Kingdome (1-4) | 31-78 | |
| » W: Floyd Bannister (6-10) L: Matt Keough (0-13) | Seventh | 30 out |
| Saturday, August 4 |
| » Defeated Mariners (47-64), 5-3 | Kingdome (2-4) | 32-78 | |
| » W: Mike Morgan (2-6) L: Mike Parrott (9-8) S: Dave Hamilton (2) | Seventh | 30 out |
| Sunday, August 5 |
| » Defeated Mariners (47-65), 9-8 | Kingdome (3-4) | 33-78 | Won 2 |
| » W: Brian Kingman (2-4) L: John Montague (5-4) S: Dave Hamilton (3) | Seventh | 29½ out |
| Monday, August 6 |
| » Lost to Angels (64-49), 5-2 | Oakland-Alameda County Stadium (20-38) | 33-79 | |
| » W: Ralph Botting (2-0) L: Steve McCatty (7-6) S: Mark Clear (12) | Seventh | 30½ out |
| Tuesday, August 7 |
| » Defeated Angels (64-50), 9-5 | Oakland-Alameda County Stadium (21-38) | 34-79 | |
| » W: Rick Langford (7-12) L: Jim Barr (7-9) | Seventh | 29½ out |
| Wednesday, August 8 |
| » Lost to Angels (65-50), 8-1 | Oakland-Alameda County Stadium (21-39) | 34-80 | |
| » W: Dave Frost (11-7) L: Matt Keough (0-14) | Seventh | 30½ out |
| Friday, August 10 |
| » Defeated Twins (59-53), 6-5 | Metropolitan Stadium (2-2) | 35-80 | |
| » W: Dave Heaverlo (4-9) L: Mike Marshall (10-10) | Seventh | 30 out |
| » Lost to Twins (60-53), 3-2 | Metropolitan Stadium (2-3) | 35-81 | |
| » W: Darrell Jackson (3-3) L: Dave Heaverlo (4-10) | Seventh | 30 out |
| Saturday, August 11 |
| » Lost to Twins (61-53), 9-7 | Metropolitan Stadium (2-4) | 35-82 | Lost 2 |
| » W: Mike Bacsik (3-1) L: Steve McCatty (7-7) S: Mike Marshall (25) | Seventh | 31 out |
| Sunday, August 12 |
| » Lost to Twins (62-53), 1-0 | Metropolitan Stadium (2-5) | 35-83 | Lost 3 |
| » W: Jerry Koosman (14-10) L: Rick Langford (7-13) | Seventh | 32 out |
| Monday, August 13 |
| » Lost to Blue Jays (37-81), 4-2 | Oakland-Alameda County Stadium (21-40) | 35-84 | Lost 4 |
| » W: Butch Edge (1-0) L: Mike Norris (3-5) S: Tom Buskey (5) | Seventh | 32 out |
| Tuesday, August 14 |
| » Lost to Blue Jays (38-81), 6-2 | Oakland-Alameda County Stadium (21-41) | 35-85 | Lost 5 |
| » W: Phil Huffman (5-13) L: Craig Minetto (1-4) | Seventh | 32 out |
| Wednesday, August 15 |
| » Defeated Blue Jays (38-82), 3-1 | Oakland-Alameda County Stadium (22-41) | 36-85 | |
| » W: Brian Kingman (3-4) L: Jesse Jefferson (1-10) S: Dave Heaverlo (9) | Seventh | 31 out |
| Thursday, August 16 |
| » Major-league debuts: John Tudor (Red Sox) |
| Friday, August 17 |
| » Defeated Indians (61-60), 5-3 | Oakland-Alameda County Stadium (23-41) | 37-85 | Won 2 |
| » W: Steve McCatty (8-7) L: Dan Spillner (7-3) | Seventh | 30 out |
| Saturday, August 18 |
| » Defeated Indians (61-61), 4-1 | Oakland-Alameda County Stadium (24-41) | 38-85 | Won 3 |
| » W: Rick Langford (8-13) L: Rick Wise (13-7) | Seventh | 30 out |
| Sunday, August 19 |
| » Defeated Indians (61-62), 3-2 | Oakland-Alameda County Stadium (25-41) | 39-85 | Won 4 |
| » W: Mike Norris (4-5) L: Rick Waits (12-11) | Seventh | 30 out |
| Monday, August 20 |
| » Lost to Tigers (64-59), 7-3 | Oakland-Alameda County Stadium (25-42) | 39-86 | |
| » W: Dan Petry (5-3) L: Dave Heaverlo (4-11) | Seventh | 31 out |
| Tuesday, August 21 |
| » Defeated Tigers (64-60), 8-1 | Oakland-Alameda County Stadium (26-42) | 40-86 | |
| » W: Brian Kingman (4-4) L: Mike Chris (2-1) | Seventh | 30 out |
| Wednesday, August 22 |
| » Lost to Tigers (65-60), 3-1 | Oakland-Alameda County Stadium (26-43) | 40-87 | |
| » W: Milt Wilcox (11-6) L: Steve McCatty (8-8) S: Aurelio Lopez (13) | Seventh | 30 out |
| Thursday, August 23 |
| » Defeated Indians (63-64), 8-6 | Cleveland Stadium (1-2) | 41-87 | |
| » W: Rick Langford (9-13) L: Sid Monge (7-9) | Seventh | 29½ out |
| Friday, August 24 |
| » Lost to Indians (64-64), 5-2 | Cleveland Stadium (1-3) | 41-88 | |
| » W: Rick Waits (13-11) L: Mike Norris (4-6) | Seventh | 29½ out |
| Saturday, August 25 |
| » Lost to Indians (65-64), 5-3 | Cleveland Stadium (1-4) | 41-89 | Lost 2 |
| » W: Len Barker (4-4) L: Mike Morgan (2-7) S: Victor Cruz (9) | Seventh | 30½ out |
| Sunday, August 26 |
| » Lost to Indians (66-64), 7-5 | Cleveland Stadium (1-5) | 41-90 | Lost 3 |
| » W: Wayne Garland (4-8) L: Brian Kingman (4-5) S: Sid Monge (17) | Seventh | 30½ out |
| Monday, August 27 |
| » Lost to Blue Jays (42-88), 7-0 | Exhibition Stadium (0-4) | 41-91 | Lost 4 |
| » W: Phil Huffman (6-14) L: Steve McCatty (8-9) | Seventh | 30½ out |
| Tuesday, August 28 |
| » Defeated Blue Jays (42-89), 6-3 | Exhibition Stadium (1-4) | 42-91 | |
| » W: Rick Langford (10-13) L: Dave Stieb (5-5) | Seventh | 29½ out |
| Wednesday, August 29 |
| » Defeated Blue Jays (42-90), 6-4 | Exhibition Stadium (2-4) | 43-91 | Won 2 |
| » W: Mike Norris (5-6) L: Tom Underwood (6-16) | Seventh | 28½ out |
| Thursday, August 30 |
| » Lost to Tigers (72-61), 8-7 | Tiger Stadium (0-3) | 43-92 | |
| » W: Dave Tobik (3-4) L: Craig Minetto (1-5) | Seventh | 29 out |
| Friday, August 31 |
| » Defeated Tigers (72-62), 5-3 | Tiger Stadium (1-3) | 44-92 | |
| » W: Brian Kingman (5-5) L: Dave Tobik (3-5) S: Dave Hamilton (4) | Seventh | 28½ out |
| Saturday, September 1 |
| » Defeated Tigers (72-63), 6-3 | Tiger Stadium (2-3) | 45-92 | Won 2 |
| » W: Steve McCatty (9-9) L: Aurelio Lopez (7-4) S: Dave Hamilton (5) | Seventh | 28½ out |
| Sunday, September 2 |
| » Defeated Tigers (72-64), 5-4 | Tiger Stadium (3-3) | 46-92 | Won 3 |
| » W: Rick Langford (11-13) L: Bruce Robbins (3-3) | Seventh | 28½ out |
| Monday, September 3 |
| » Lost to Brewers (83-56), 6-3 | Oakland-Alameda County Stadium (26-44) | 46-93 | |
| » W: Jim Slaton (13-8) L: Mike Norris (5-7) S: Jerry Augustine (5) | Seventh | 29½ out |
| Tuesday, September 4 |
| » Major-league debuts: Rich Dotson (White Sox) |
| Wednesday, September 5 |
| » Defeated Brewers (83-57), 6-1 | Oakland-Alameda County Stadium (27-44) | 47-93 | |
| » W: Matt Keough (1-14) L: Mike Caldwell (14-6) | Seventh | 29 out |
| Friday, September 7 |
| » Defeated White Sox (60-79), 4-3 | Oakland-Alameda County Stadium (28-44) | 48-93 | Won 2 |
| » W: Rick Langford (12-13) L: Mike Proly (2-7) | Seventh | 29½ out |
| Saturday, September 8 |
| » Defeated White Sox (60-80), 2-1 | Oakland-Alameda County Stadium (29-44) | 49-93 | Won 3 |
| » W: Steve McCatty (10-9) L: Mike Proly (2-8) | Seventh | 29½ out |
| Sunday, September 9 |
| » Defeated White Sox (60-81), 3-0 | Oakland-Alameda County Stadium (30-44) | 50-93 | Won 4 |
| » W: Brian Kingman (6-5) L: Steve Trout (8-8) | Seventh | 30 out |
| » Lost to White Sox (61-81), 7-0 | Oakland-Alameda County Stadium (30-45) | 50-94 | |
| » W: Richard Dotson (1-0) L: Mike Norris (5-8) | Seventh | 30 out |
| Tuesday, September 11 |
| » Lost to Brewers (84-60), 5-0 | County Stadium (1-3) | 50-95 | Lost 2 |
| » W: Jim Slaton (14-8) L: Matt Keough (1-15) | Seventh | 30 out |
| Wednesday, September 12 |
| » Lost to Brewers (85-60), 7-0 | County Stadium (1-4) | 50-96 | Lost 3 |
| » W: Mike Caldwell (15-6) L: Mike Morgan (2-8) | Seventh | 30 out |
| Thursday, September 13 |
| » Defeated Brewers (85-61), 8-3 | County Stadium (2-4) | 51-96 | |
| » W: Steve McCatty (11-9) L: Bill Travers (12-8) | Seventh | 29½ out |
| Friday, September 14 |
| » Defeated White Sox (63-82), 8-3 | Comiskey Park I (1-3) | 52-96 | Won 2 |
| » W: Brian Kingman (7-5) L: Ed Farmer (4-7) | Seventh | 29½ out |
| » Major-league debuts: LaMarr Hoyt (White Sox) |
| Saturday, September 15 |
| » Lost to White Sox (64-82), 3-0 | Comiskey Park I (1-4) | 52-97 | |
| » W: Steve Trout (9-8) L: Rick Langford (12-14) | Seventh | 29½ out |
| Sunday, September 16 |
| » Lost to White Sox (65-82), 5-2 | Comiskey Park I (1-5) | 52-98 | Lost 2 |
| » W: Richard Dotson (2-0) L: Matt Keough (1-16) S: Mike Proly (9) | Seventh | 29½ out |
| Monday, September 17 |
| » Lost to Rangers (75-76), 6-3 | Oakland-Alameda County Stadium (30-46) | 52-99 | Lost 3 |
| » W: Steve Comer (16-10) L: Mike Morgan (2-9) S: Jim Kern (27) | Seventh | 29½ out |
| Tuesday, September 18 |
| » Lost to Rangers (76-76), 9-5 | Oakland-Alameda County Stadium (30-47) | 52-100 | Lost 4 |
| » W: Fergie Jenkins (15-13) L: Steve McCatty (11-10) | Seventh | 30½ out |
| Wednesday, September 19 |
| » Lost to Rangers (77-76), 9-4 | Oakland-Alameda County Stadium (30-48) | 52-101 | Lost 5 |
| » W: Doyle Alexander (5-7) L: Brian Kingman (7-6) | |