| Wednesday, April 6 |
| » Major-league debuts: Jose Baez (Mariners) |
| Thursday, April 7 |
| » Major-league debuts: Al Woods (Blue Jays) |
| Friday, April 8 |
| » Major-league debuts: Julio Gonzalez (Astros) |
| Saturday, April 9 |
| » Lost to Athletics (1-0), 7-4 | Oakland-Alameda County Stadium (0-1) | 0-1 | |
| » W: Mike Torrez (1-0) L: Ron Schueler (0-1) | Fifth | 1½ out |
| Sunday, April 10 |
| » Lost to Athletics (2-0), 9-6 | Oakland-Alameda County Stadium (0-2) | 0-2 | Lost 2 |
| » W: Doc Medich (1-0) L: Pete Redfern (0-1) S: Pablo Torrealba (1) | Fifth | 2 out |
| » Defeated Athletics (2-1), 7-1 | Oakland-Alameda County Stadium (1-2) | 1-2 | |
| » W: Paul Thormodsgard (1-0) L: Jim Umbarger (0-1) S: Tom Burgmeier (1) | Fifth | 2 out |
| » Major-league debuts: Paul Thormodsgard and Rob Wilfong (Twins) |
| Monday, April 11 |
| » Defeated Mariners (2-4), 12-3 | Kingdome (1-0) | 2-2 | Won 2 |
| » W: Geoff Zahn (1-0) L: Diego Segui (0-2) | Third | 2 out |
| Tuesday, April 12 |
| » Defeated Mariners (2-5), 3-2 | Kingdome (2-0) | 3-2 | Won 3 |
| » W: Ron Schueler (1-1) L: Bill Laxton (1-1) S: Tom Burgmeier (2) | Third | 1½ out |
| Wednesday, April 13 |
| » Lost to Mariners (3-5), 3-2 | Kingdome (2-1) | 3-3 | |
| » W: Tommy Moore (1-0) L: Tom Burgmeier (0-1) | Fourth | 2 out |
| Thursday, April 14 |
| » Lost to Mariners (4-5), 4-3 | Kingdome (2-2) | 3-4 | Lost 2 |
| » W: Gary Wheelock (2-0) L: Pete Redfern (0-2) S: John Montague (2) | Fifth | 3 out |
| Friday, April 15 |
| » Lost to Athletics (7-1), 3-2 | Metropolitan Stadium (0-1) | 3-5 | Lost 3 |
| » W: Mike Torrez (2-0) L: Paul Thormodsgard (1-1) S: Dave Giusti (2) | Fifth | 4 out |
| Saturday, April 16 |
| » Defeated Athletics (7-2), 3-1 | Metropolitan Stadium (1-1) | 4-5 | |
| » W: Geoff Zahn (2-0) L: Vida Blue (0-1) | Sixth | 2 out |
| Sunday, April 17 |
| » Defeated Athletics (7-3), 10-2 | Metropolitan Stadium (2-1) | 5-5 | Won 2 |
| » W: Mike Pazik (1-0) L: Jim Umbarger (0-2) | Fifth | 2 out |
| Monday, April 18 |
| » Defeated Royals (5-4), 8-6 | Royals Stadium (1-0) | 6-5 | Won 3 |
| » W: Tom Johnson (1-0) L: Steve Mingori (0-2) | Fourth | 1½ out |
| Tuesday, April 19 |
| » Lost to Royals (6-4), 11-3 | Royals Stadium (1-1) | 6-6 | |
| » W: Jim Colborn (2-1) L: Pete Redfern (0-3) | Fifth | 1½ out |
| Wednesday, April 20 |
| » Defeated Royals (6-5), 3-2 | Royals Stadium (2-1) | 7-6 | |
| » W: Tom Burgmeier (1-1) L: Mark Littell (1-1) S: Tom Johnson (1) | Fifth | 1½ out |
| Thursday, April 21 |
| » Defeated Rangers (6-5), 11-4 | Arlington Stadium (1-0) | 8-6 | Won 2 |
| » W: Geoff Zahn (3-0) L: Gaylord Perry (1-2) | Third | 2 out |
| » Major-league debuts: Willie Norwood (Twins) |
| Friday, April 22 |
| » Defeated Rangers (6-6), 4-1 | Arlington Stadium (2-0) | 9-6 | Won 3 |
| » W: Tom Johnson (2-0) L: Bert Blyleven (1-2) | Third | 2 out |
| Saturday, April 23 |
| » Lost to Rangers (7-6), 1-0 | Arlington Stadium (2-1) | 9-7 | |
| » W: Doyle Alexander (2-1) L: Dave Goltz (0-1) | Fourth | 2 out |
| Sunday, April 24 |
| » Defeated Rangers (7-7), 12-6 | Arlington Stadium (3-1) | 10-7 | |
| » W: Pete Redfern (1-3) L: Tommy Boggs (0-2) | Fourth | 1½ out |
| Tuesday, April 26 |
| » Defeated Mariners (7-13), 5-3 | Metropolitan Stadium (3-1) | 11-7 | Won 2 |
| » W: Tom Burgmeier (2-1) L: Stan Thomas (1-1) S: Tom Johnson (2) | Third | 1½ out |
| Wednesday, April 27 |
| » Defeated Mariners (7-14), 5-3 | Metropolitan Stadium (4-1) | 12-7 | Won 3 |
| » W: Tom Johnson (3-0) L: Tommy Moore (1-1) S: Tom Burgmeier (3) | First | -- |
| Thursday, April 28 |
| » Lost to Mariners (8-14), 4-3 | Metropolitan Stadium (4-2) | 12-8 | |
| » W: John Montague (2-2) L: Dave Goltz (0-2) | Third | ½ out |
| Friday, April 29 |
| » Lost to Tigers (8-11), 6-5 | Metropolitan Stadium (4-3) | 12-9 | Lost 2 |
| » W: Steve Foucault (1-1) L: Tom Johnson (3-1) S: John Hiller (3) | Fourth | 1½ out |
| Saturday, April 30 |
| » Defeated Tigers (8-12), 7-3 | Metropolitan Stadium (5-3) | 13-9 | |
| » W: Geoff Zahn (4-0) L: Dave Roberts (1-4) | First | -- |
| Sunday, May 1 |
| » Defeated Tigers (8-13), 6-5 | Metropolitan Stadium (6-3) | 14-9 | Won 2 |
| » W: Jeff Holly (1-0) L: John Hiller (1-3) | First | -- |
| Tuesday, May 3 |
| » Defeated Indians (7-13), 4-3 | Cleveland Stadium (1-0) | 15-9 | Won 3 |
| » W: Tom Burgmeier (3-1) L: Jim Kern (0-2) S: Tom Johnson (3) | First | -- |
| Wednesday, May 4 |
| » Lost to Indians (8-13), 6-5 | Cleveland Stadium (1-1) | 15-10 | |
| » W: Don Hood (1-0) L: Tom Johnson (3-2) S: Dave LaRoche (3) | First | -- |
| Friday, May 6 |
| » Defeated Blue Jays (12-15), 7-2 | Exhibition Stadium (1-0) | 16-10 | |
| » W: Geoff Zahn (5-0) L: Dave Lemanczyk (2-3) S: Ron Schueler (1) | First | -- |
| Saturday, May 7 |
| » Defeated Blue Jays (12-16), 4-1 | Exhibition Stadium (2-0) | 17-10 | Won 2 |
| » W: Paul Thormodsgard (2-1) L: Steve Hargan (1-3) S: Tom Johnson (4) | First | -- |
| Sunday, May 8 |
| » Defeated Blue Jays (12-17), 5-4 | Exhibition Stadium (3-0) | 18-10 | Won 3 |
| » W: Dave Goltz (1-2) L: Jesse Jefferson (0-3) S: Tom Johnson (5) | First | -- |
| Tuesday, May 10 |
| » Defeated Tigers (10-16), 7-5 | Tiger Stadium (1-0) | 19-10 | Won 4 |
| » W: Jeff Holly (2-0) L: Bob Sykes (0-1) S: Tom Burgmeier (4) | First | -- |
| Wednesday, May 11 |
| » Lost to Tigers (11-16), 8-3 | Tiger Stadium (1-1) | 19-11 | |
| » W: Dave Roberts (3-4) L: Geoff Zahn (5-1) | First | -- |
| Friday, May 13 |
| » Defeated Blue Jays (14-18), 4-3 | Metropolitan Stadium (7-3) | 20-11 | |
| » W: Ron Schueler (2-1) L: Mike Willis (1-1) | First | -- |
| Saturday, May 14 |
| » Defeated Blue Jays (14-19), 13-3 | Metropolitan Stadium (8-3) | 21-11 | Won 2 |
| » W: Dave Goltz (2-2) L: Bill Singer (2-5) | First | -- |
| Sunday, May 15 |
| » Defeated Blue Jays (14-20), 5-3 | Metropolitan Stadium (9-3) | 22-11 | Won 3 |
| » W: Tom Burgmeier (4-1) L: Jerry Garvin (5-1) S: Ron Schueler (2) | First | -- |
| Monday, May 16 |
| » Defeated Indians (12-19), 8-1 | Metropolitan Stadium (10-3) | 23-11 | Won 4 |
| » W: Geoff Zahn (6-1) L: Wayne Garland (1-5) | First | -- |
| Tuesday, May 17 |
| » Defeated Indians (12-20), 10-4 | Metropolitan Stadium (11-3) | 24-11 | Won 5 |
| » W: Tom Burgmeier (5-1) L: Pat Dobson (0-4) | First | -- |
| Thursday, May 19 |
| » Lost to Angels (17-20), 5-3 | Anaheim Stadium (0-1) | 24-12 | |
| » W: Nolan Ryan (6-4) L: Dave Goltz (2-3) | First | -- |
| Friday, May 20 |
| » Lost to Angels (18-20), 3-0 | Anaheim Stadium (0-2) | 24-13 | Lost 2 |
| » W: Frank Tanana (7-1) L: Paul Thormodsgard (2-2) | First | -- |
| Saturday, May 21 |
| » Lost to Angels (19-20), 5-1 | Anaheim Stadium (0-3) | 24-14 | Lost 3 |
| » W: Gary Ross (1-2) L: Geoff Zahn (6-2) S: Dave LaRoche (6) | First | -- |
| Sunday, May 22 |
| » Defeated Angels (19-21), 8-5 | Anaheim Stadium (1-3) | 25-14 | |
| » W: Tom Johnson (4-2) L: Mickey Scott (0-2) | First | -- |
| Wednesday, May 25 |
| » Defeated Red Sox (21-18), 13-5 | Fenway Park (1-0) | 26-14 | Won 2 |
| » W: Dave Goltz (3-3) L: Bob Stanley (3-1) S: Tom Burgmeier (5) | First | -- |
| » Defeated Red Sox (21-19), 9-4 | Fenway Park (2-0) | 27-14 | Won 3 |
| » W: Paul Thormodsgard (3-2) L: Mike Paxton (0-1) | First | -- |
| » Major-league debuts: Mike Paxton (Red Sox) |
| Friday, May 27 |
| » Lost to Orioles (24-16), 6-0 | Memorial Stadium (0-1) | 27-15 | |
| » W: Rudy May (6-4) L: Geoff Zahn (6-3) | First | -- |
| Saturday, May 28 |
| » Lost to Orioles (25-16), 3-1 | Memorial Stadium (0-2) | 27-16 | Lost 2 |
| » W: Jim Palmer (7-3) L: Jeff Holly (2-1) | First | -- |
| Sunday, May 29 |
| » Defeated Orioles (25-17), 3-2 | Memorial Stadium (1-2) | 28-16 | |
| » W: Dave Goltz (4-3) L: Mike Flanagan (1-3) S: Tom Johnson (6) | First | -- |
| Monday, May 30 |
| » Lost to Orioles (26-17), 9-7 | Metropolitan Stadium (11-4) | 28-17 | |
| » W: Ross Grimsley (5-3) L: Ron Schueler (2-2) S: Scott McGregor (2) | First | -- |
| Tuesday, May 31 |
| » Defeated Orioles (26-18), 8-3 | Metropolitan Stadium (12-4) | 29-17 | |
| » W: Pete Redfern (2-3) L: Rudy May (6-5) | First | -- |
| Wednesday, June 1 |
| » Defeated Yankees (26-22), 4-3 | Metropolitan Stadium (13-4) | 30-17 | Won 2 |
| » W: Tom Johnson (5-2) L: Ron Guidry (3-2) | First | -- |
| Thursday, June 2 |
| » Lost to Yankees (27-22), 10-3 | Metropolitan Stadium (13-5) | 30-18 | |
| » W: Ed Figueroa (7-3) L: Jeff Holly (2-2) S: Sparky Lyle (9) | First | -- |
| Friday, June 3 |
| » Defeated Red Sox (25-23), 6-2 | Metropolitan Stadium (14-5) | 31-18 | |
| » W: Dave Goltz (5-3) L: Bob Stanley (3-3) | First | -- |
| Saturday, June 4 |
| » Lost to Red Sox (26-23), 5-2 | Metropolitan Stadium (14-6) | 31-19 | |
| » W: Bill Lee (3-1) L: Paul Thormodsgard (3-3) | First | -- |
| Sunday, June 5 |
| » Lost to Red Sox (27-23), 5-1 | Metropolitan Stadium (14-7) | 31-20 | Lost 2 |
| » W: Reggie Cleveland (4-3) L: Tom Burgmeier (5-2) S: Bill Campbell (9) | First | -- |
| Monday, June 6 |
| » Lost to White Sox (29-21), 9-5 | Metropolitan Stadium (14-8) | 31-21 | Lost 3 |
| » W: Lerrin LaGrow (2-0) L: Ron Schueler (2-3) | First | -- |
| Tuesday, June 7 |
| » Defeated White Sox (29-22), 6-5 | Metropolitan Stadium (15-8) | 32-21 | |
| » W: Tom Johnson (6-2) L: Larry Anderson (0-1) | First | -- |
| Wednesday, June 8 |
| » Defeated Royals (25-27), 9-8 | Metropolitan Stadium (16-8) | 33-21 | Won 2 |
| » W: Dave Johnson (1-0) L: Larry Gura (3-2) | First | -- |
| Thursday, June 9 |
| » Lost to Royals (26-27), 7-2 | Metropolitan Stadium (16-9) | 33-22 | |
| » W: Andy Hassler (3-1) L: Pete Redfern (2-4) S: Steve Mingori (1) | First | -- |
| Friday, June 10 |
| » Lost to Yankees (33-24), 4-1 | Yankee Stadium (0-1) | 33-23 | Lost 2 |
| » W: Ron Guidry (4-2) L: Geoff Zahn (6-4) S: Sparky Lyle (12) | First | -- |
| Saturday, June 11 |
| » Lost to Yankees (34-24), 6-5 | Yankee Stadium (0-2) | 33-24 | Lost 3 |
| » W: Catfish Hunter (3-3) L: Dave Goltz (5-4) S: Sparky Lyle (13) | First | -- |
| Sunday, June 12 |
| » Defeated Yankees (34-25), 6-1 | Yankee Stadium (1-2) | 34-24 | |
| » W: Paul Thormodsgard (4-3) L: Ed Figueroa (7-5) | First | -- |
| Tuesday, June 14 |
| » Lost to Angels (29-27), 12-9 | Metropolitan Stadium (16-10) | 34-25 | |
| » W: Dyar Miller (3-2) L: Ron Schueler (2-4) S: Dave LaRoche (8) | First | -- |
| Wednesday, June 15 |
| » Defeated Angels (29-28), 3-2 | Metropolitan Stadium (17-10) | 35-25 | |
| » W: Dave Goltz (6-4) L: Frank Tanana (10-3) | First | -- |
| Thursday, June 16 |
| » Defeated Angels (29-29), 7-6 | Metropolitan Stadium (18-10) | 36-25 | Won 2 |
| » W: Tom Johnson (7-2) L: Nolan Ryan (9-6) | First | -- |
| Friday, June 17 |
| » Lost to Royals (29-31), 7-1 | Royals Stadium (2-2) | 36-26 | |
| » W: Jim Colborn (7-7) L: Geoff Zahn (6-5) | First | -- |
| Saturday, June 18 |
| » Lost to Royals (30-31), 2-1 | Royals Stadium (2-3) | 36-27 | Lost 2 |
| » W: Paul Splittorff (6-4) L: Bill Butler (0-1) S: Mark Littell (7) | First | -- |
| Sunday, June 19 |
| » Lost to Royals (31-31), 8-7 | Royals Stadium (2-4) | 36-28 | Lost 3 |
| » W: Larry Gura (4-3) L: Dave Johnson (1-1) | Second | 1 out |
| Monday, June 20 |
| » Lost to Rangers (31-30), 2-1 | Metropolitan Stadium (18-11) | 36-29 | Lost 4 |
| » W: Dock Ellis (3-6) L: Paul Thormodsgard (4-4) S: Paul Lindblad (3) | Second | 1 out |
| Tuesday, June 21 |
| » Defeated Rangers (31-31), 9-5 | Metropolitan Stadium (19-11) | 37-29 | |
| » W: Ron Schueler (3-4) L: Doyle Alexander (6-4) S: Tom Johnson (7) | Second | 1 out |
| Wednesday, June 22 |
| » Lost to Rangers (32-31), 10-8 | Metropolitan Stadium (19-12) | 37-30 | |
| » W: Darold Knowles (2-0) L: Tom Burgmeier (5-3) S: Mike Marshall (1) | Second | 1 out |
| Thursday, June 23 |
| » Defeated Rangers (32-32), 12-2 | Metropolitan Stadium (20-12) | 38-30 | |
| » W: Dave Goltz (7-4) L: Nelson Briles (3-4) | Second | 1 out |
| » Major-league debuts: Gary Gray (Rangers) |
| Friday, June 24 |
| » Defeated White Sox (37-30), 7-6 | Metropolitan Stadium (21-12) | 39-30 | Won 2 |
| » W: Tom Johnson (8-2) L: Lerrin LaGrow (3-1) | First | -- |
| Saturday, June 25 |
| » Lost to White Sox (38-30), 8-1 | Metropolitan Stadium (21-13) | 39-31 | |
| » W: Chris Knapp (6-4) L: Geoff Zahn (6-6) | Second | 1 out |
| Sunday, June 26 |
| » Defeated White Sox (38-31), 19-12 | Metropolitan Stadium (22-13) | 40-31 | |
| » W: Tom Johnson (9-2) L: Steve Stone (8-6) | First | -- |
| Monday, June 27 |
| » Defeated Brewers (35-37), 10-3 | Metropolitan Stadium (23-13) | 41-31 | Won 2 |
| » W: Dave Goltz (8-4) L: Jerry Augustine (8-9) | First | -- |
| Tuesday, June 28 |
| » Defeated Brewers (35-38), 8-3 | Metropolitan Stadium (24-13) | 42-31 | Won 3 |
| » W: Paul Thormodsgard (5-4) L: Gary Beare (2-3) | First | -- |
| Wednesday, June 29 |
| » Lost to Brewers (36-38), 1-0 | Metropolitan Stadium (24-14) | 42-32 | |
| » W: Lary Sorensen (2-1) L: Dave Johnson (1-2) S: Bill Castro (9) | First | -- |
| Friday, July 1 |
| » Lost to White Sox (41-32), 5-2 | Comiskey Park I (0-1) | 42-33 | Lost 2 |
| » W: Chris Knapp (7-4) L: Dave Goltz (8-5) | Second | 1 out |
| Saturday, July 2 |
| » Lost to White Sox (42-32), 13-8 | Comiskey Park I (0-2) | 42-34 | Lost 3 |
| » W: Lerrin LaGrow (4-1) L: Tom Johnson (9-3) | Second | 1 out |
| Sunday, July 3 |
| » Lost to White Sox (43-32), 6-0 | Comiskey Park I (0-3) | 42-35 | Lost 4 |
| » W: Wilbur Wood (2-2) L: Geoff Zahn (6-7) | Second | 3 out |
| » Lost to White Sox (44-32), 10-8 | Comiskey Park I (0-4) | 42-36 | Lost 5 |
| » W: Ken Kravec (4-2) L: Jeff Holly (2-3) | Second | 3 out |
| Monday, July 4 |
| » Defeated Brewers (38-40), 5-0 | County Stadium (1-0) | 43-36 | |
| » W: Paul Thormodsgard (6-4) L: Lary Sorensen (2-2) | Second | 3 out |
| Tuesday, July 5 |
| » Defeated Brewers (38-41), 3-2 | County Stadium (2-0) | 44-36 | Won 2 |
| » W: Dave Goltz (9-5) L: Mike Caldwell (1-1) | Second | 3 out |
| Wednesday, July 6 |
| » Defeated Angels (39-38), 4-3 | Metropolitan Stadium (25-14) | 45-36 | Won 3 |
| » W: Tom Johnson (10-3) L: Paul Hartzell (3-6) | Second | 3 out |
| Future Twin Michael Ryan is born in Indiana, PA. |
| Thursday, July 7 |
| » Defeated Angels (39-39), 8-6 | Metropolitan Stadium (26-14) | 46-36 | Won 4 |
| » W: Ron Schueler (4-4) L: Frank Tanana (12-6) S: Tom Johnson (8) | Second | 2½ out |
| Friday, July 8 |
| » Lost to Mariners (36-50), 13-11 | Metropolitan Stadium (26-15) | 46-37 | |
| » W: Bill Laxton (3-2) L: Paul Thormodsgard (6-5) S: Enrique Romo (6) | Second | 3½ out |
| Saturday, July 9 |
| » Lost to Mariners (37-50), 5-2 | Metropolitan Stadium (26-16) | 46-38 | Lost 2 |
| » W: Dick Pole (5-5) L: Dave Goltz (9-6) S: Enrique Romo (7) | Second | 4½ out |
| Sunday, July 10 |
| » Defeated Mariners (37-51), 15-0 | Metropolitan Stadium (27-16) | 47-38 | |
| » W: Geoff Zahn (7-7) L: Stan Thomas (2-6) | Second | 3½ out |
| Monday, July 11 |
| » Lost to Angels (40-42), 6-5 | Anaheim Stadium (1-4) | 47-39 | |
| » W: Dave LaRoche (6-2) L: Dave Johnson (1-3) | Second | 4½ out |
| Tuesday, July 12 |
| » Lost to Angels (41-42), 3-0 | Anaheim Stadium (1-5) | 47-40 | Lost 2 |
| » W: Nolan Ryan (12-8) L: Paul Thormodsgard (6-6) | Third | 4½ out |
| Wednesday, July 13 |
| » Defeated Angels (41-43), 6-3 | Anaheim Stadium (2-5) | 48-40 | |
| » W: Dave Goltz (10-6) L: Wayne Simpson (4-7) | Third | 4 out |
| Friday, July 15 |
| » Lost to Athletics (38-49), 8-7 | Oakland-Alameda County Stadium (1-3) | 48-41 | |
| » W: Dave Giusti (3-3) L: Dave Johnson (1-4) | Third | 5½ out |
| Saturday, July 16 |
| » Lost to Athletics (39-49), 8-2 | Oakland-Alameda County Stadium (1-4) | 48-42 | Lost 2 |
| » W: Vida Blue (8-11) L: Pete Redfern (2-5) | Third | 5½ out |
| Sunday, July 17 |
| » Defeated Athletics (39-50), 4-1 | Oakland-Alameda County Stadium (2-4) | 49-42 | |
| » W: Paul Thormodsgard (7-6) L: Rick Langford (7-9) | Third | 5 out |
| » Defeated Athletics (39-51), 9-5 | Oakland-Alameda County Stadium (3-4) | 50-42 | Won 2 |
| » W: Geoff Zahn (8-7) L: Joe Coleman (1-1) S: Tom Johnson (9) | Third | 5 out |
| Thursday, July 21 |
| » Defeated Angels (42-47), 3-2 | Metropolitan Stadium (28-16) | 51-42 | Won 3 |
| » W: Dave Goltz (11-6) L: Nolan Ryan (13-9) | Third | 4½ out |
| Friday, July 22 |
| » Lost to Angels (43-47), 6-2 | Metropolitan Stadium (28-17) | 51-43 | |
| » W: Ken Brett (7-8) L: Paul Thormodsgard (7-7) | Third | 5½ out |
| » Major-league debuts: Gary Serum (Twins) |
| Saturday, July 23 |
| » Defeated Angels (43-48), 10-4 | Metropolitan Stadium (29-17) | 52-43 | |
| » W: Pete Redfern (3-5) L: Mike Barlow (0-1) | Third | 5½ out |
| Sunday, July 24 |
| » Defeated Athletics (40-54), 5-3 | Metropolitan Stadium (30-17) | 53-43 | Won 2 |
| » W: Geoff Zahn (9-7) L: Bob Lacey (3-5) S: Tom Johnson (10) | Third | 5 out |
| » Defeated Athletics (40-55), 10-9 | Metropolitan Stadium (31-17) | 54-43 | Won 3 |
| » W: Tom Johnson (11-3) L: Doug Bair (1-1) | Third | 5 out |
| Monday, July 25 |
| » Defeated Athletics (40-56), 2-1 | Metropolitan Stadium (32-17) | 55-43 | Won 4 |
| » W: Dave Goltz (12-6) L: Rick Langford (7-11) | Third | 5 out |
| Tuesday, July 26 |
| » Lost to Mariners (44-58), 9-7 | Kingdome (2-3) | 55-44 | |
| » W: Glenn Abbott (7-7) L: Paul Thormodsgard (7-8) S: Diego Segui (2) | Third | 6 out |
| Wednesday, July 27 |
| » Defeated Mariners (44-59), 4-1 | Kingdome (3-3) | 56-44 | |
| » W: Pete Redfern (4-5) L: Tom House (3-5) | Third | 5 out |
| Thursday, July 28 |
| » Lost to Mariners (45-59), 5-2 | Kingdome (3-4) | 56-45 | |
| » W: Gary Wheelock (6-6) L: Geoff Zahn (9-8) S: John Montague (3) | Third | 5½ out |
| Friday, July 29 |
| » Defeated Indians (43-54), 3-1 | Cleveland Stadium (2-1) | 57-45 | |
| » W: Paul Thormodsgard (8-8) L: Wayne Garland (7-12) S: Tom Johnson (11) | Third | 5½ out |
| Saturday, July 30 |
| » Defeated Indians (43-55), 4-3 | Cleveland Stadium (3-1) | 58-45 | Won 2 |
| » W: Tom Johnson (12-3) L: Sid Monge (1-2) | Third | 5½ out |
| Sunday, July 31 |
| » Lost to Indians (44-55), 9-2 | Cleveland Stadium (3-2) | 58-46 | |
| » W: Al Fitzmorris (3-6) L: Pete Redfern (4-6) | Third | 5½ out |
| » Defeated Indians (44-56), 9-4 | Cleveland Stadium (4-2) | 59-46 | |
| » W: Dave Johnson (2-4) L: Rick Waits (5-4) S: Tom Burgmeier (6) | Third | 5½ out |
| Monday, August 1 |
| » Defeated Royals (56-44), 9-5 | Metropolitan Stadium (33-17) | 60-46 | Won 2 |
| » W: Geoff Zahn (10-8) L: Jim Colborn (11-10) S: Tom Johnson (12) | Second | 4½ out |
| Tuesday, August 2 |
| » Defeated Royals (56-45), 9-4 | Metropolitan Stadium (34-17) | 61-46 | Won 3 |
| » W: Dave Goltz (13-6) L: Andy Hassler (6-4) | Second | 3½ out |
| Wednesday, August 3 |
| » Defeated Tigers (46-56), 11-1 | Metropolitan Stadium (35-17) | 62-46 | Won 4 |
| » W: Paul Thormodsgard (9-8) L: Fernando Arroyo (6-10) | Second | 2½ out |
| Thursday, August 4 |
| » Lost to Tigers (47-56), 4-2 | Metropolitan Stadium (35-18) | 62-47 | |
| » W: Dave Rozema (11-4) L: Pete Redfern (4-7) | Second | 3½ out |
| Friday, August 5 |
| » Defeated Indians (46-58), 14-10 | Metropolitan Stadium (36-18) | 63-47 | |
| » W: Geoff Zahn (11-8) L: Sid Monge (1-3) S: Tom Johnson (13) | Second | 2½ out |
| Saturday, August 6 |
| » Defeated Indians (46-59), 6-5 | Metropolitan Stadium (37-18) | 64-47 | Won 2 |
| » W: Pete Redfern (5-7) L: Wayne Garland (8-13) | Second | 2½ out |
| Sunday, August 7 |
| » Defeated Indians (46-60), 11-1 | Metropolitan Stadium (38-18) | 65-47 | Won 3 |
| » W: Dave Goltz (14-6) L: Dennis Eckersley (10-9) | Second | 2½ out |
| Tuesday, August 9 |
| » Lost to Blue Jays (39-70), 6-2 | Exhibition Stadium (3-1) | 65-48 | |
| » W: Jesse Jefferson (7-12) L: Paul Thormodsgard (9-9) | Second | 2 out |
| Thursday, August 11 |
| » Defeated Blue Jays (39-71), 7-3 | Exhibition Stadium (4-1) | 66-48 | |
| » W: Dave Goltz (15-6) L: Jeff Byrd (2-5) S: Tom Johnson (14) | Second | 1½ out |
| Friday, August 12 |
| » Defeated Tigers (51-61), 12-11 | Tiger Stadium (2-1) | 67-48 | Won 2 |
| » W: Tom Burgmeier (6-3) L: Fernando Arroyo (6-12) S: Tom Johnson (15) | First | -- |
| Saturday, August 13 |
| » Lost to Tigers (52-61), 2-1 | Tiger Stadium (2-2) | 67-49 | |
| » W: Milt Wilcox (4-0) L: Geoff Zahn (11-9) S: Steve Foucault (9) | Second | 1½ out |
| Sunday, August 14 |
| » Lost to Tigers (53-61), 6-5 | Tiger Stadium (2-3) | 67-50 | Lost 2 |
| » W: Dave Rozema (13-4) L: Tom Johnson (12-4) | Second | 1½ out |
| Monday, August 15 |
| » Defeated Orioles (67-49), 13-9 | Memorial Stadium (2-2) | 68-50 | |
| » W: Ron Schueler (5-4) L: Rudy May (13-11) | First | -- |
| Tuesday, August 16 |
| » Lost to Orioles (68-49), 6-5 | Memorial Stadium (2-3) | 68-51 | |
| » W: Dennis Martinez (11-6) L: Tom Johnson (12-5) | First | -- |
| Wednesday, August 17 |
| » Lost to Mariners (50-72), 3-2 | Metropolitan Stadium (38-19) | 68-52 | Lost 2 |
| » W: Paul Mitchell (1-4) L: Geoff Zahn (11-10) S: Enrique Romo (11) | Third | 1½ out |
| Thursday, August 18 |
| » Defeated Mariners (50-73), 8-2 | Metropolitan Stadium (39-19) | 69-52 | |
| » W: Paul Thormodsgard (10-9) L: Bob Galasso (0-3) | Second | 1½ out |
| Friday, August 19 |
| » Lost to Orioles (69-49), 3-2 | Metropolitan Stadium (39-20) | 69-53 | |
| » W: Mike Flanagan (9-9) L: Dave Goltz (15-7) | Fourth | 2½ out |
| Saturday, August 20 |
| » Lost to Orioles (70-49), 6-2 | Metropolitan Stadium (39-21) | 69-54 | Lost 2 |
| » W: Ross Grimsley (12-6) L: Pete Redfern (5-8) S: Dennis Martinez (3) | Fourth | 2 out |
| Sunday, August 21 |
| » Defeated Orioles (70-50), 9-5 | Metropolitan Stadium (40-21) | 70-54 | |
| » W: Ron Schueler (6-4) L: Rudy May (13-12) | Third | 2 out |
| Monday, August 22 |
| » Defeated Red Sox (71-49), 5-4 | Metropolitan Stadium (41-21) | 71-54 | Won 2 |
| » W: Tom Johnson (13-5) L: Bill Lee (4-3) | Third | 2 out |
| Tuesday, August 23 |
| » Defeated Red Sox (71-50), 7-0 | Metropolitan Stadium (42-21) | 72-54 | Won 3 |
| » W: Dave Goltz (16-7) L: Fergie Jenkins (10-8) | Second | 2 out |
| Wednesday, August 24 |
| » Lost to Yankees (74-51), 11-1 | Yankee Stadium (1-3) | 72-55 | |
| » W: Catfish Hunter (9-7) L: Pete Redfern (5-9) | Third | 2 out |
| Thursday, August 25 |
| » Lost to Yankees (75-51), 6-4 | Yankee Stadium (1-4) | 72-56 | Lost 2 |
| » W: Sparky Lyle (9-4) L: Tom Johnson (13-6) | Fourth | 3 out |
| Friday, August 26 |
| » Defeated Red Sox (72-53), 6-4 | Fenway Park (3-0) | 73-56 | |
| » W: Tom Johnson (14-6) L: Rick Kreuger (0-1) | Third | 3 out |
| Saturday, August 27 |
| » Lost to Red Sox (73-53), 7-5 | Fenway Park (3-1) | 73-57 | |
| » W: Bill Lee (5-3) L: Ron Schueler (6-5) S: Jim Willoughby (2) | Third | 3 out |
| Sunday, August 28 |
| » Lost to Red Sox (74-53), 6-5 | Fenway Park (3-2) | 73-58 | Lost 2 |
| » W: Mike Paxton (7-4) L: Ron Schueler (6-6) S: Bill Campbell (22) | Fourth | 4 out |
| Monday, August 29 |
| » Defeated Blue Jays (45-83), 7-6 | Metropolitan Stadium (43-21) | 74-58 | |
| » W: Ron Schueler (7-6) L: Tom Murphy (1-2) | Second | 2½ out |
| » Defeated Blue Jays (45-84), 6-5 | Metropolitan Stadium (44-21) | 75-58 | Won 2 |
| » W: Tom Johnson (15-6) L: Mike Willis (2-6) | Second | 2½ out |
| Wednesday, August 31 |
| » Lost to Athletics (52-78), 4-3 | Metropolitan Stadium (44-22) | 75-59 | |
| » W: Doc Medich (8-6) L: Paul Thormodsgard (10-10) S: Doug Bair (3) | Third | 3 out |
| Friday, September 2 |
| » Lost to Yankees (81-52), 4-0 | Metropolitan Stadium (44-23) | 75-60 | Lost 2 |
| » W: Ron Guidry (12-6) L: Dave Goltz (16-8) | Fourth | 4½ out |
| Saturday, September 3 |
| » Lost to Yankees (82-52), 7-4 | Metropolitan Stadium (44-24) | 75-61 | Lost 3 |
| » W: Ed Figueroa (13-9) L: Ron Schueler (7-7) | Fourth | 5½ out |
| Sunday, September 4 |
| » Lost to Yankees (83-52), 4-0 | Metropolitan Stadium (44-25) | 75-62 | Lost 4 |
| » W: Don Gullett (11-3) L: Geoff Zahn (11-11) | Fourth | 6½ out |
| Monday, September 5 |
| » Defeated Rangers (74-61), 5-4 | Metropolitan Stadium (45-25) | 76-62 | |
| » W: Paul Thormodsgard (11-10) L: Doyle Alexander (13-10) S: Tom Burgmeier (7) | Third | 6½ out |
| » Major-league debuts: Eddie Miller (Rangers) |
| Tuesday, September 6 |
| » Defeated Rangers (74-62), 7-4 | Metropolitan Stadium (46-25) | 77-62 | Won 2 |
| » W: Dave Goltz (17-8) L: Bert Blyleven (13-12) | Third | 6½ out |
| Wednesday, September 7 |
| » Lost to Rangers (75-62), 4-3 | Metropolitan Stadium (46-26) | 77-63 | |
| » W: Dock Ellis (8-12) L: Tom Johnson (15-7) S: Roger Moret (3) | Third | 7½ out |
| Friday, September 9 |
| » Lost to Royals (85-54), 6-3 | Metropolitan Stadium (46-27) | 77-64 | Lost 2 |
| » W: Marty Pattin (8-2) L: Paul Thormodsgard (11-11) S: Doug Bird (12) | Third | 9 out |
| Saturday, September 10 |
| » Lost to Royals (86-54), 10-1 | Metropolitan Stadium (46-28) | 77-65 | Lost 3 |
| » W: Paul Splittorff (14-6) L: Dave Goltz (17-9) | Fourth | 10 out |
| Sunday, September 11 |
| » Lost to Royals (87-54), 4-1 | Metropolitan Stadium (46-29) | 77-66 | Lost 4 |
| » W: Andy Hassler (9-5) L: Geoff Zahn (11-12) | Fourth | 11 out |
| Monday, September 12 |
| » Lost to White Sox (80-63), 7-3 | Comiskey Park I (0-5) | 77-67 | Lost 5 |
| » W: Dave Hamilton (4-4) L: Tom Burgmeier (6-4) | Fourth | 11½ out |
| Tuesday, September 13 |
| » Lost to White Sox (81-63), 6-1 | Comiskey Park I (0-6) | 77-68 | Lost 6 |
| » W: Francisco Barrios (13-5) L: Paul Thormodsgard (11-12) | Fourth | 12 out |
| Wednesday, September 14 |
| » Defeated White Sox (81-64), 7-0 | Comiskey Park I (1-6) | 78-68 | |
| » W: Dave Goltz (18-9) L: Ken Kravec (8-8) | Fourth | 12½ out |
| Thursday, September 15 |
| » Defeated White Sox (81-65), 7-2 | Comiskey Park I (2-6) | 79-68 | Won 2 |
| » W: Geoff Zahn (12-12) L: Steve Stone (14-11) | Fourth | 13 out |
| Friday, September 16 |
| » Defeated Rangers (80-66), 9-7 | Arlington Stadium (4-1) | 80-68 | Won 3 |
| » W: Tom Johnson (16-7) L: Roger Moret (3-3) | Fourth | 12 out |
| » Major-league debuts: John Poloni (Rangers) |
| Saturday, September 17 |
| » Lost to Rangers (81-66), 5-4 | Arlington Stadium (4-2) | 80-69 | |
| » W: Len Barker (3-1) L: Don Carrithers (0-1) | Fourth | 13 out |
| Sunday, September 18 |
| » Lost to Rangers (82-66), 5-4 | Arlington Stadium (4-3) | 80-70 | Lost 2 |
| » W: Gaylord Perry (13-12) L: Paul Thormodsgard (11-13) S: Adrian Devine (13) | Fourth | 14½ out |
| » Lost to Rangers (83-66), 10-8 | Arlington Stadium (4-4) | 80-71 | Lost 3 |
| » W: Jim Umbarger (2-6) L: Dave Goltz (18-10) S: Adrian Devine (14) | Fourth | 14½ out |
| Tuesday, September 20 |
| » Lost to Royals (94-55), 4-2 | Royals Stadium (2-5) | 80-72 | Lost 4 |
| » W: Paul Splittorff (15-6) L: Geoff Zahn (12-13) | Fourth | 15½ out |
| Wednesday, September 21 |
| » Lost to Royals (95-55), 10-5 | Royals Stadium (2-6) | 80-73 | Lost 5 |
| » W: Jim Colborn (18-13) L: Dave Johnson (2-5) | Fourth | 16½ out |
| Saturday, September 24 |
| » Defeated Brewers (64-91), 4-3 | Metropolitan Stadium (47-29) | 81-73 | |
| » W: Dave Goltz (19-10) L: Moose Haas (10-12) | Fourth | 17 out |
| Sunday, September 25 |
| » Lost to Brewers (65-91), 8-6 | Metropolitan Stadium (47-30) | 81-74 | |
| » W: Lary Sorensen (7-9) L: Paul Thormodsgard (11-14) S: Eduardo Rodriguez (4) | Fourth | 18 out |
| » Defeated Brewers (65-92), 8-4 | Metropolitan Stadium (48-30) | 82-74 | |
| » W: Ron Schueler (8-7) L: Bill Travers (4-11) | Fourth | 18 out |
| Tuesday, September 27 |
| » Lost to White Sox (88-70), 8-6 | Metropolitan Stadium (48-31) | 82-75 | |
| » W: Chris Knapp (12-7) L: Geoff Zahn (12-14) S: Dave Hamilton (9) | Fourth | 17 out |
| Wednesday, September 28 |
| » Lost to White Sox (89-70), 4-3 | Metropolitan Stadium (48-32) | 82-76 | Lost 2 |
| » W: Steve Renko (7-2) L: Dave Goltz (19-11) S: Lerrin LaGrow (25) | Fourth | 17 out |
| Friday, September 30 |
| » Lost to Brewers (67-93), 7-5 | County Stadium (2-1) | 82-77 | Lost 3 |
| » W: Mike Caldwell (5-8) L: Paul Thormodsgard (11-15) | Fourth | 18½ out |
| Saturday, October 1 |
| » Defeated Brewers (67-94), 9-1 | County Stadium (3-1) | 83-77 | |
| » W: Pete Redfern (6-9) L: Lary Sorensen (7-10) S: Ron Schueler (3) | Fourth | 17½ out |
| Sunday, October 2 |
| » Defeated Brewers (67-95), 6-2 | County Stadium (4-1) | 84-77 | Won 2 |
| » W: Dave Goltz (20-11) L: Bill Travers (4-12) | Fourth | 17½ out |
| Saturday, October 22 |
| Future Twin Brad Thomas is born in Sydney, Australia. |
| Friday, December 30 |
| Future Twin Grant Balfour is born in Sydney, Australia. |
Game information provided by Retrosheet (www.retrosheet.org) |