| Sunday, January 16 |
| Former Red Sox Baby Doll Jacobson dies in Orion, IL at the age of 87. |
| Friday, February 4 |
| Former Red Sox Nemo Leibold dies in Detroit, MI at the age of 85. |
| Thursday, February 24 |
| Future Red Sox Bronson Arroyo is born in Key West, FL. |
| Thursday, March 31 |
| Future Red Sox Jamie Brown is born in Meridian, MS. |
| Wednesday, April 6 |
| » Major-league debuts: Jose Baez (Mariners) |
| Thursday, April 7 |
| » Lost to Indians (1-0), 5-4 | Fenway Park (0-1) | 0-1 | |
| » W: Dave LaRoche (1-0) L: Bill Campbell (0-1) | Second | 1 out |
| » Major-league debuts: Jim Norris (Indians) |
| Sunday, April 10 |
| » Lost to Indians (2-0), 19-9 | Fenway Park (0-2) | 0-2 | Lost 2 |
| » W: Dave LaRoche (2-0) L: Bill Campbell (0-2) | Fourth | 2 out |
| Tuesday, April 12 |
| » Lost to White Sox (2-2), 5-2 | Comiskey Park I (0-1) | 0-3 | Lost 3 |
| » W: Ken Brett (1-1) L: Rick Wise (0-1) S: Dave Hamilton (1) | Sixth | 2 out |
| Wednesday, April 13 |
| » Lost to White Sox (3-2), 7-3 | Comiskey Park I (0-2) | 0-4 | Lost 4 |
| » W: Bart Johnson (1-0) L: Fergie Jenkins (0-1) S: Lerrin LaGrow (2) | Seventh | 3 out |
| Saturday, April 16 |
| » Defeated Indians (3-2), 8-4 | Cleveland Stadium (1-0) | 1-4 | |
| » W: Luis Tiant (1-0) L: Wayne Garland (0-1) S: Bob Stanley (1) | Sixth | 3 out |
| » Major-league debuts: Bob Stanley (Red Sox) |
| Sunday, April 17 |
| » Defeated Indians (3-3), 4-1 | Cleveland Stadium (2-0) | 2-4 | Won 2 |
| » W: Reggie Cleveland (1-0) L: Al Fitzmorris (0-1) | Sixth | 3½ out |
| » Lost to Indians (4-3), 10-5 | Cleveland Stadium (2-1) | 2-5 | |
| » W: Jim Bibby (1-0) L: Tom Murphy (0-1) S: Dave LaRoche (1) | Sixth | 3½ out |
| Monday, April 18 |
| » Defeated Tigers (3-8), 5-3 | Fenway Park (1-2) | 3-5 | |
| » W: Fergie Jenkins (1-1) L: Fernando Arroyo (0-2) S: Jim Willoughby (1) | Fourth | 3 out |
| Tuesday, April 19 |
| » Defeated Tigers (3-9), 11-3 | Fenway Park (2-2) | 4-5 | Won 2 |
| » W: Bob Stanley (1-0) L: Ray Bare (0-2) | Fourth | 3 out |
| Wednesday, April 20 |
| » Lost to Tigers (4-9), 3-2 | Fenway Park (2-3) | 4-6 | |
| » W: Vern Ruhle (2-1) L: Luis Tiant (1-1) S: John Hiller (1) | Fourth | 3 out |
| Thursday, April 21 |
| » Lost to Tigers (5-9), 8-0 | Fenway Park (2-4) | 4-7 | Lost 2 |
| » W: Dave Rozema (1-0) L: Reggie Cleveland (1-1) | Fifth | 3½ out |
| Sunday, April 24 |
| » Defeated Blue Jays (7-8), 9-0 | Exhibition Stadium (1-0) | 5-7 | |
| » W: Fergie Jenkins (2-1) L: Bill Singer (0-3) | Fourth | 3½ out |
| Monday, April 25 |
| » Lost to Blue Jays (8-8), 4-3 | Exhibition Stadium (1-1) | 5-8 | |
| » W: Pete Vuckovich (1-1) L: Bill Campbell (0-3) | Fifth | 3½ out |
| » Defeated Blue Jays (8-9), 6-5 | Exhibition Stadium (2-1) | 6-8 | |
| » W: Jim Willoughby (1-0) L: Pete Vuckovich (1-2) | Fifth | 3½ out |
| Tuesday, April 26 |
| » Defeated Brewers (9-5), 3-1 | County Stadium (1-0) | 7-8 | Won 2 |
| » W: Rick Wise (1-1) L: Jerry Augustine (2-2) S: Bill Campbell (1) | Fourth | 2½ out |
| Wednesday, April 27 |
| » Lost to Brewers (10-5), 4-2 | County Stadium (1-1) | 7-9 | |
| » W: Bill Castro (3-0) L: Reggie Cleveland (1-2) | Fourth | 3½ out |
| Friday, April 29 |
| » Defeated Athletics (12-8), 7-4 | Fenway Park (3-4) | 8-9 | |
| » W: Fergie Jenkins (3-1) L: Dock Ellis (1-2) S: Bill Campbell (2) | Fourth | 3½ out |
| Saturday, April 30 |
| » Defeated Athletics (12-9), 8-4 | Fenway Park (4-4) | 9-9 | Won 2 |
| » W: Luis Tiant (2-1) L: Mike Norris (1-1) | Fourth | 2½ out |
| Sunday, May 1 |
| » Defeated Athletics (12-10), 6-4 | Fenway Park (5-4) | 10-9 | Won 3 |
| » W: Bill Campbell (1-3) L: Stan Bahnsen (1-1) | Fourth | 2 out |
| Tuesday, May 3 |
| » Lost to Mariners (9-17), 10-8 | Fenway Park (5-5) | 10-10 | |
| » W: John Montague (3-2) L: Rick Wise (1-2) S: Dave Pagan (2) | Fourth | 3½ out |
| Wednesday, May 4 |
| » Defeated Mariners (9-18), 5-2 | Fenway Park (6-5) | 11-10 | |
| » W: Reggie Cleveland (2-2) L: Stan Thomas (1-3) S: Bill Campbell (3) | Fourth | 2½ out |
| Thursday, May 5 |
| » Defeated Mariners (9-19), 5-2 | Fenway Park (7-5) | 12-10 | Won 2 |
| » W: Fergie Jenkins (4-1) L: Diego Segui (0-4) | Fourth | 1½ out |
| Friday, May 6 |
| » Lost to Angels (10-15), 8-4 | Fenway Park (7-6) | 12-11 | |
| » W: Nolan Ryan (4-3) L: Luis Tiant (2-2) S: Paul Hartzell (1) | Third | 1½ out |
| Saturday, May 7 |
| » Defeated Angels (10-16), 3-0 | Fenway Park (8-6) | 13-11 | |
| » W: Bob Stanley (2-0) L: Frank Tanana (4-1) | Fourth | 1½ out |
| Sunday, May 8 |
| » Defeated Angels (10-17), 4-3 | Fenway Park (9-6) | 14-11 | Won 2 |
| » W: Jim Willoughby (2-0) L: Gary Ross (0-2) | Fourth | 1½ out |
| » Major-league debuts: Gil Flores (Angels) |
| Former Red Sox Frankie Pytlak dies in Buffalo, NY at the age of 69. |
| Monday, May 9 |
| » Lost to Athletics (15-14), 2-1 | Oakland-Alameda County Stadium (0-1) | 14-12 | |
| » W: Vida Blue (3-2) L: Reggie Cleveland (2-3) | Fourth | 2 out |
| Wednesday, May 11 |
| » Lost to Athletics (16-14), 3-1 | Oakland-Alameda County Stadium (0-2) | 14-13 | Lost 2 |
| » W: Doc Medich (2-2) L: Fergie Jenkins (4-2) | Third | 2 out |
| Friday, May 13 |
| » Defeated Mariners (11-25), 7-5 | Kingdome (1-0) | 15-13 | |
| » W: Jim Willoughby (3-0) L: Enrique Romo (0-2) S: Bill Campbell (4) | Third | 1½ out |
| Saturday, May 14 |
| » Defeated Mariners (11-26), 8-4 | Kingdome (2-0) | 16-13 | Won 2 |
| » W: Bob Stanley (3-0) L: Stan Thomas (1-5) S: Bill Campbell (5) | Third | 1½ out |
| Sunday, May 15 |
| » Defeated Mariners (11-27), 5-4 | Kingdome (3-0) | 17-13 | Won 3 |
| » W: Bill Lee (1-0) L: Rick Jones (0-2) S: Bill Campbell (6) | Third | 1 out |
| Monday, May 16 |
| » Defeated Angels (15-20), 8-7 | Anaheim Stadium (1-0) | 18-13 | Won 4 |
| » W: Bill Campbell (2-3) L: Paul Hartzell (1-4) | Second | 1 out |
| Tuesday, May 17 |
| » Lost to Angels (16-20), 6-2 | Anaheim Stadium (1-1) | 18-14 | |
| » W: Wayne Simpson (3-3) L: Fergie Jenkins (4-3) S: Paul Hartzell (3) | Third | ½ out |
| » Major-league debuts: Willie Aikens (Angels) |
| Wednesday, May 18 |
| » Major-league debuts: Tim Corcoran (Tigers) |
| Friday, May 20 |
| » Lost to Brewers (20-18), 15-7 | Fenway Park (9-7) | 18-15 | Lost 2 |
| » W: Jerry Augustine (5-4) L: Luis Tiant (2-3) | Third | 1 out |
| Saturday, May 21 |
| » Defeated Brewers (20-19), 10-9 | Fenway Park (10-7) | 19-15 | |
| » W: Tom House (1-0) L: Bill Castro (4-2) | Second | ½ out |
| Sunday, May 22 |
| » Defeated Brewers (20-20), 14-10 | Fenway Park (11-7) | 20-15 | Won 2 |
| » W: Bill Campbell (3-3) L: Rich Folkers (0-1) | Second | ½ out |
| » Lost to Brewers (21-20), 6-0 | Fenway Park (11-8) | 20-16 | |
| » W: Eduardo Rodriguez (1-0) L: Fergie Jenkins (4-4) | Second | ½ out |
| Monday, May 23 |
| » Defeated Yankees (21-18), 4-3 | Yankee Stadium (1-0) | 21-16 | |
| » W: Bill Lee (2-0) L: Ed Figueroa (5-3) S: Bill Campbell (7) | Second | ½ out |
| Tuesday, May 24 |
| » Lost to Yankees (22-18), 6-5 | Yankee Stadium (1-1) | 21-17 | |
| » W: Dick Tidrow (3-2) L: Luis Tiant (2-4) | Second | 1½ out |
| Wednesday, May 25 |
| » Lost to Twins (26-14), 13-5 | Fenway Park (11-9) | 21-18 | Lost 2 |
| » W: Dave Goltz (3-3) L: Bob Stanley (3-1) S: Tom Burgmeier (5) | Third | 2½ out |
| » Lost to Twins (27-14), 9-4 | Fenway Park (11-10) | 21-19 | Lost 3 |
| » W: Paul Thormodsgard (3-2) L: Mike Paxton (0-1) | Third | 2½ out |
| » Major-league debuts: Mike Paxton (Red Sox) |
| Friday, May 27 |
| » Defeated Royals (19-22), 10-1 | Fenway Park (12-10) | 22-19 | |
| » W: Fergie Jenkins (5-4) L: Dennis Leonard (2-5) | Third | 2½ out |
| Saturday, May 28 |
| » Defeated Royals (19-23), 17-12 | Fenway Park (13-10) | 23-19 | Won 2 |
| » W: Bill Campbell (4-3) L: Marty Pattin (0-2) | Second | 2½ out |
| Sunday, May 29 |
| » Lost to Royals (20-23), 3-0 | Fenway Park (13-11) | 23-20 | |
| » W: Jim Colborn (6-5) L: Bob Stanley (3-2) S: Mark Littell (5) | Third | 2½ out |
| Monday, May 30 |
| » Lost to Yankees (26-20), 5-4 | Fenway Park (13-12) | 23-21 | Lost 2 |
| » W: Mike Torrez (6-3) L: Bill Lee (2-1) | Third | 3½ out |
| Tuesday, May 31 |
| » Defeated Yankees (26-21), 5-1 | Fenway Park (14-12) | 24-21 | |
| » W: Reggie Cleveland (3-3) L: Gil Patterson (1-2) | Third | 2½ out |
| Wednesday, June 1 |
| » Defeated Rangers (21-22), 7-5 | Arlington Stadium (1-0) | 25-21 | Won 2 |
| » W: Mike Paxton (1-1) L: Doyle Alexander (6-2) S: Bill Campbell (8) | Second | 1½ out |
| Thursday, June 2 |
| » Lost to Rangers (22-22), 3-1 | Arlington Stadium (1-1) | 25-22 | |
| » W: Darold Knowles (1-0) L: Fergie Jenkins (5-5) | Third | 1½ out |
| Friday, June 3 |
| » Lost to Twins (31-18), 6-2 | Metropolitan Stadium (0-1) | 25-23 | Lost 2 |
| » W: Dave Goltz (5-3) L: Bob Stanley (3-3) | Third | 2½ out |
| Saturday, June 4 |
| » Defeated Twins (31-19), 5-2 | Metropolitan Stadium (1-1) | 26-23 | |
| » W: Bill Lee (3-1) L: Paul Thormodsgard (3-3) | Third | 2 out |
| Sunday, June 5 |
| » Defeated Twins (31-20), 5-1 | Metropolitan Stadium (2-1) | 27-23 | Won 2 |
| » W: Reggie Cleveland (4-3) L: Tom Burgmeier (5-2) S: Bill Campbell (9) | Third | 1 out |
| Monday, June 6 |
| » Defeated Royals (24-26), 1-0 | Royals Stadium (1-0) | 28-23 | Won 3 |
| » W: Luis Tiant (3-4) L: Dennis Leonard (3-6) S: Bill Campbell (10) | Third | 1 out |
| Tuesday, June 7 |
| » Lost to Royals (25-26), 5-4 | Royals Stadium (1-1) | 28-24 | |
| » W: Mark Littell (5-2) L: Mike Paxton (1-2) | Third | 1 out |
| Wednesday, June 8 |
| » Defeated Orioles (29-24), 14-5 | Fenway Park (15-12) | 29-24 | |
| » W: Rick Wise (2-2) L: Dennis Martinez (4-3) | Second | 1 out |
| Thursday, June 9 |
| » Defeated Orioles (29-25), 7-3 | Fenway Park (16-12) | 30-24 | Won 2 |
| » W: Bill Lee (4-1) L: Jim Palmer (7-6) S: Bill Campbell (11) | Second | 1 out |
| Sunday, June 12 |
| » Defeated Rangers (26-26), 3-2 | Fenway Park (17-12) | 31-24 | Won 3 |
| » W: Reggie Cleveland (5-3) L: Adrian Devine (4-3) | Second | 1½ out |
| » Defeated Rangers (26-27), 2-0 | Fenway Park (18-12) | 32-24 | Won 4 |
| » W: Luis Tiant (4-4) L: Nelson Briles (2-3) | Second | 1½ out |
| Monday, June 13 |
| » Defeated White Sox (31-26), 5-4 | Fenway Park (19-12) | 33-24 | Won 5 |
| » W: Bill Campbell (5-3) L: Larry Anderson (1-2) | First | -- |
| Tuesday, June 14 |
| » Defeated White Sox (31-27), 7-1 | Fenway Park (20-12) | 34-24 | Won 6 |
| » W: Rick Wise (3-2) L: Chris Knapp (5-3) S: Bill Campbell (12) | First | -- |
| Thursday, June 16 |
| » Lost to White Sox (32-27), 7-3 | Fenway Park (20-13) | 34-25 | |
| » W: Steve Stone (7-5) L: Luis Tiant (4-5) S: Lerrin LaGrow (9) | Second | 1½ out |
| Friday, June 17 |
| » Defeated Yankees (36-27), 9-4 | Fenway Park (21-13) | 35-25 | |
| » W: Bob Stanley (4-3) L: Ken Clay (0-1) S: Bill Campbell (13) | First | -- |
| Saturday, June 18 |
| » Defeated Yankees (36-28), 10-4 | Fenway Park (22-13) | 36-25 | Won 2 |
| » W: Reggie Cleveland (6-3) L: Mike Torrez (7-6) S: Bill Campbell (14) | First | -- |
| Sunday, June 19 |
| » Defeated Yankees (36-29), 11-1 | Fenway Park (23-13) | 37-25 | Won 3 |
| » W: Fergie Jenkins (6-5) L: Ed Figueroa (7-6) | First | -- |
| Monday, June 20 |
| » Defeated Orioles (35-29), 4-0 | Memorial Stadium (1-0) | 38-25 | Won 4 |
| » W: Rick Wise (4-2) L: Rudy May (9-6) | First | -- |
| Tuesday, June 21 |
| » Defeated Orioles (35-30), 7-0 | Memorial Stadium (2-0) | 39-25 | Won 5 |
| » W: Luis Tiant (5-5) L: Dennis Martinez (6-5) | First | -- |
| Wednesday, June 22 |
| » Defeated Orioles (35-31), 7-4 | Memorial Stadium (3-0) | 40-25 | Won 6 |
| » W: Mike Paxton (2-2) L: Jim Palmer (8-7) S: Bill Campbell (15) | First | -- |
| Thursday, June 23 |
| » Defeated Orioles (35-32), 7-3 | Memorial Stadium (4-0) | 41-25 | Won 7 |
| » W: Fergie Jenkins (7-5) L: Mike Flanagan (2-8) | First | -- |
| Friday, June 24 |
| » Lost to Yankees (38-31), 6-5 | Yankee Stadium (1-2) | 41-26 | |
| » W: Sparky Lyle (4-2) L: Ramon Hernandez (0-1) | First | -- |
| Saturday, June 25 |
| » Lost to Yankees (39-31), 5-1 | Yankee Stadium (1-3) | 41-27 | Lost 2 |
| » W: Mike Torrez (8-6) L: Luis Tiant (5-6) | First | -- |
| Sunday, June 26 |
| » Lost to Yankees (40-31), 5-4 | Yankee Stadium (1-4) | 41-28 | Lost 3 |
| » W: Sparky Lyle (5-2) L: Bill Campbell (5-4) | First | -- |
| Monday, June 27 |
| » Lost to Tigers (32-38), 4-1 | Tiger Stadium (0-1) | 41-29 | Lost 4 |
| » W: Dave Roberts (4-7) L: Rick Wise (4-3) | First | -- |
| Future Red Sox Juan Pena is born in Santo Domingo, D.R. |
| Tuesday, June 28 |
| » Lost to Tigers (33-38), 3-2 | Tiger Stadium (0-2) | 41-30 | Lost 5 |
| » W: Jim Crawford (2-1) L: Bill Campbell (5-5) | First | -- |
| Wednesday, June 29 |
| » Lost to Tigers (34-38), 7-2 | Tiger Stadium (0-3) | 41-31 | Lost 6 |
| » W: Mark Fidrych (6-2) L: Bill Lee (4-2) | First | -- |
| Friday, July 1 |
| » Lost to Orioles (40-36), 8-2 | Fenway Park (23-14) | 41-32 | Lost 7 |
| » W: Jim Palmer (9-8) L: Luis Tiant (5-7) | First | -- |
| Saturday, July 2 |
| » Lost to Orioles (41-36), 5-2 | Fenway Park (23-15) | 41-33 | Lost 8 |
| » W: Mike Flanagan (4-8) L: Reggie Cleveland (6-4) | Second | 1½ out |
| Sunday, July 3 |
| » Lost to Orioles (42-36), 12-8 | Fenway Park (23-16) | 41-34 | Lost 9 |
| » W: Dennis Martinez (8-5) L: Rick Wise (4-4) S: Dick Drago (3) | Second | 2 out |
| Monday, July 4 |
| » Defeated Blue Jays (30-48), 9-6 | Fenway Park (24-16) | 42-34 | |
| » W: Bill Campbell (6-5) L: Chuck Hartenstein (0-2) | Second | 2 out |
| Wednesday, July 6 |
| » Defeated Blue Jays (30-49), 9-5 | Fenway Park (25-16) | 43-34 | Won 2 |
| » W: Bill Campbell (7-5) L: Pete Vuckovich (4-7) | Third | 2 out |
| Thursday, July 7 |
| » Defeated Blue Jays (30-50), 5-2 | Fenway Park (26-16) | 44-34 | Won 3 |
| » W: Bob Stanley (5-3) L: Jesse Jefferson (5-8) S: Bill Campbell (16) | Second | 2 out |
| Friday, July 8 |
| » Defeated Brewers (38-43), 7-3 | County Stadium (2-1) | 45-34 | Won 4 |
| » W: Reggie Cleveland (7-4) L: Jim Slaton (6-8) | Second | 2 out |
| Saturday, July 9 |
| » Lost to Brewers (39-43), 3-2 | County Stadium (2-2) | 45-35 | |
| » W: Jerry Augustine (10-9) L: Fergie Jenkins (7-6) S: Bill Castro (10) | Second | 2 out |
| Sunday, July 10 |
| » Defeated Brewers (39-44), 8-5 | County Stadium (3-2) | 46-35 | |
| » W: Bill Campbell (8-5) L: Eduardo Rodriguez (1-4) | First | -- |
| » Defeated Brewers (39-45), 7-3 | County Stadium (4-2) | 47-35 | Won 2 |
| » W: Rick Wise (5-4) L: Mike Caldwell (1-2) | First | -- |
| Monday, July 11 |
| » Defeated Indians (39-42), 2-1 | Cleveland Stadium (3-1) | 48-35 | Won 3 |
| » W: Bob Stanley (6-3) L: Jim Bibby (8-6) | First | -- |
| Tuesday, July 12 |
| » Lost to Indians (40-42), 7-1 | Cleveland Stadium (3-2) | 48-36 | |
| » W: Dennis Eckersley (9-7) L: Reggie Cleveland (7-5) | First | -- |
| Wednesday, July 13 |
| » Defeated Indians (40-43), 9-7 | Cleveland Stadium (4-2) | 49-36 | |
| » W: Bill Campbell (9-5) L: Jim Kern (3-5) S: Bill Lee (1) | First | -- |
| Thursday, July 14 |
| » Defeated Indians (40-44), 7-4 | Cleveland Stadium (5-2) | 50-36 | Won 2 |
| » W: Mike Paxton (3-2) L: Al Fitzmorris (2-5) S: Ramon Hernandez (2) | First | -- |
| Friday, July 15 |
| » Lost to White Sox (53-35), 9-7 | Comiskey Park I (0-3) | 50-37 | |
| » W: Wilbur Wood (4-2) L: Bob Stanley (6-4) S: Lerrin LaGrow (15) | Second | 1½ out |
| Saturday, July 16 |
| » Defeated White Sox (53-36), 4-3 | Comiskey Park I (1-3) | 51-37 | |
| » W: Rick Wise (6-4) L: Francisco Barrios (9-4) S: Bill Campbell (17) | Second | 1½ out |
| Sunday, July 17 |
| » Lost to White Sox (54-36), 3-2 | Comiskey Park I (1-4) | 51-38 | |
| » W: Steve Stone (10-7) L: Reggie Cleveland (7-6) S: Lerrin LaGrow (16) | Second | 1½ out |
| Thursday, July 21 |
| » Defeated Indians (41-48), 11-4 | Fenway Park (27-16) | 52-38 | |
| » W: Luis Tiant (6-7) L: Wayne Garland (7-10) | Second | ½ out |
| » Lost to Indians (42-48), 8-2 | Fenway Park (27-17) | 52-39 | |
| » W: Jim Bibby (9-7) L: Bob Stanley (6-5) S: Jim Kern (13) | Second | ½ out |
| Friday, July 22 |
| » Defeated Indians (42-49), 3-0 | Fenway Park (28-17) | 53-39 | |
| » W: Rick Wise (7-4) L: Al Fitzmorris (2-6) | First | -- |
| Saturday, July 23 |
| » Lost to Indians (43-49), 9-8 | Fenway Park (28-18) | 53-40 | |
| » W: Jim Kern (4-6) L: Bill Campbell (9-6) | First | -- |
| Sunday, July 24 |
| » Lost to White Sox (57-36), 9-6 | Fenway Park (28-19) | 53-41 | Lost 2 |
| » W: Francisco Barrios (10-4) L: Fergie Jenkins (7-7) | Second | 1 out |
| Monday, July 25 |
| » Lost to White Sox (58-36), 8-7 | Fenway Park (28-20) | 53-42 | Lost 3 |
| » W: Lerrin LaGrow (5-1) L: Bill Campbell (9-7) | Second | 2 out |
| Tuesday, July 26 |
| » Defeated Brewers (43-55), 4-3 | Fenway Park (29-20) | 54-42 | |
| » W: Don Aase (1-0) L: Lary Sorensen (2-4) | Second | 1 out |
| » Major-league debuts: Don Aase (Red Sox) |
| Wednesday, July 27 |
| » Lost to Brewers (44-55), 14-5 | Fenway Park (29-21) | 54-43 | |
| » W: Bob McClure (2-0) L: Bob Stanley (6-6) | Second | 2 out |
| Thursday, July 28 |
| » Defeated Brewers (44-56), 12-0 | Fenway Park (30-21) | 55-43 | |
| » W: Mike Paxton (4-2) L: Sam Hinds (0-3) | Second | 1 out |
| Friday, July 29 |
| » Defeated Angels (47-51), 6-5 | Anaheim Stadium (2-1) | 56-43 | Won 2 |
| » W: Bill Campbell (10-7) L: Dyar Miller (5-4) | Second | 1 out |
| Saturday, July 30 |
| » Defeated Angels (47-52), 3-0 | Anaheim Stadium (3-1) | 57-43 | Won 3 |
| » W: Luis Tiant (7-7) L: Nolan Ryan (14-10) S: Bob Stanley (2) | Second | 1 out |
| Sunday, July 31 |
| » Defeated Angels (47-53), 1-0 | Anaheim Stadium (4-1) | 58-43 | Won 4 |
| » W: Don Aase (2-0) L: Dave LaRoche (6-4) | First | -- |
| Tuesday, August 2 |
| » Defeated Mariners (46-62), 3-2 | Kingdome (4-0) | 59-43 | Won 5 |
| » W: Bill Campbell (11-7) L: John Montague (5-9) | First | -- |
| Wednesday, August 3 |
| » Defeated Mariners (46-63), 12-4 | Kingdome (5-0) | 60-43 | Won 6 |
| » W: Mike Paxton (5-2) L: Gary Wheelock (6-7) | First | -- |
| Thursday, August 4 |
| » Defeated Athletics (42-63), 3-1 | Oakland-Alameda County Stadium (1-2) | 61-43 | Won 7 |
| » W: Fergie Jenkins (8-7) L: Vida Blue (10-13) | First | -- |
| Future Red Sox Paxton Crawford is born in Little Rock, AR. |
| Friday, August 5 |
| » Defeated Athletics (42-64), 1-0 | Oakland-Alameda County Stadium (2-2) | 62-43 | Won 8 |
| » W: Luis Tiant (8-7) L: Joe Coleman (2-3) | First | -- |
| Saturday, August 6 |
| » Defeated Athletics (42-65), 2-1 | Oakland-Alameda County Stadium (3-2) | 63-43 | Won 9 |
| » W: Don Aase (3-0) L: Pablo Torrealba (3-3) S: Bill Campbell (18) | First | -- |
| Sunday, August 7 |
| » Defeated Athletics (42-66), 5-2 | Oakland-Alameda County Stadium (4-2) | 64-43 | Won 10 |
| » W: Rick Wise (8-4) L: Rick Langford (7-13) S: Bill Campbell (19) | First | -- |
| Wednesday, August 10 |
| » Defeated Angels (54-55), 11-10 | Fenway Park (31-21) | 65-43 | Won 11 |
| » W: Jim Willoughby (4-0) L: Dyar Miller (5-5) | First | -- |
| Thursday, August 11 |
| » Lost to Angels (55-55), 7-3 | Fenway Park (31-22) | 65-44 | |
| » W: Paul Hartzell (5-7) L: Don Aase (3-1) | First | -- |
| Friday, August 12 |
| » Defeated Mariners (48-69), 7-2 | Fenway Park (32-22) | 66-44 | |
| » W: Rick Wise (9-4) L: Paul Mitchell (0-4) | First | -- |
| Saturday, August 13 |
| » Defeated Mariners (48-70), 13-6 | Fenway Park (33-22) | 67-44 | Won 2 |
| » W: Fergie Jenkins (9-7) L: Bob Galasso (0-2) | First | -- |
| Sunday, August 14 |
| » Defeated Mariners (48-71), 11-1 | Fenway Park (34-22) | 68-44 | Won 3 |
| » W: Mike Paxton (6-2) L: Gary Wheelock (6-9) | First | -- |
| Monday, August 15 |
| » Defeated Royals (64-50), 2-1 | Fenway Park (35-22) | 69-44 | Won 4 |
| » W: Reggie Cleveland (8-6) L: Jim Colborn (12-12) S: Bill Campbell (20) | First | -- |
| Tuesday, August 16 |
| » Defeated Royals (64-51), 5-3 | Fenway Park (36-22) | 70-44 | Won 5 |
| » W: Bill Campbell (12-7) L: Doug Bird (8-4) | First | -- |
| Wednesday, August 17 |
| » Lost to Brewers (53-70), 5-3 | County Stadium (4-3) | 70-45 | |
| » W: Lary Sorensen (4-6) L: Rick Wise (9-5) | First | -- |
| Thursday, August 18 |
| » Defeated Brewers (53-71), 8-4 | County Stadium (5-3) | 71-45 | |
| » W: Fergie Jenkins (10-7) L: Mike Caldwell (3-6) | First | -- |
| Friday, August 19 |
| » Lost to Royals (67-51), 9-3 | Royals Stadium (1-2) | 71-46 | |
| » W: Jim Colborn (13-12) L: Mike Paxton (6-3) | First | -- |
| Future Red Sox Matt White is born in Pittsfield, MA. Former Red Sox Bob Klinger dies in Villa Ridge, MO at the age of 70. |
| Saturday, August 20 |
| » Lost to Royals (68-51), 5-2 | Royals Stadium (1-3) | 71-47 | Lost 2 |
| » W: Mark Littell (6-4) L: Luis Tiant (8-8) S: Doug Bird (6) | First | -- |
| Sunday, August 21 |
| » Lost to Royals (69-51), 6-4 | Royals Stadium (1-4) | 71-48 | Lost 3 |
| » W: Doug Bird (9-4) L: Bill Campbell (12-8) | First | -- |
| Monday, August 22 |
| » Lost to Twins (71-54), 5-4 | Metropolitan Stadium (2-2) | 71-49 | Lost 4 |
| » W: Tom Johnson (13-5) L: Bill Lee (4-3) | First | -- |
| Tuesday, August 23 |
| » Lost to Twins (72-54), 7-0 | Metropolitan Stadium (2-3) | 71-50 | Lost 5 |
| » W: Dave Goltz (16-7) L: Fergie Jenkins (10-8) | Second | 1½ out |
| Wednesday, August 24 |
| » Lost to Rangers (70-54), 3-0 | Fenway Park (36-23) | 71-51 | Lost 6 |
| » W: Gaylord Perry (11-10) L: Mike Paxton (6-4) S: Adrian Devine (11) | Second | 2 out |
| » Lost to Rangers (71-54), 6-3 | Fenway Park (36-24) | 71-52 | Lost 7 |
| » W: Len Barker (2-1) L: Reggie Cleveland (8-7) | Second | 2 out |
| Thursday, August 25 |
| » Defeated Rangers (71-55), 9-6 | Fenway Park (37-24) | 72-52 | |
| » W: Jim Willoughby (5-0) L: Darold Knowles (5-2) S: Bill Campbell (21) | Second | 2 out |
| » Major-league debuts: Sam Bowen (Red Sox) |
| Friday, August 26 |
| » Lost to Twins (73-56), 6-4 | Fenway Park (37-25) | 72-53 | |
| » W: Tom Johnson (14-6) L: Rick Kreuger (0-1) | Second | 3 out |
| Saturday, August 27 |
| » Defeated Twins (73-57), 7-5 | Fenway Park (38-25) | 73-53 | |
| » W: Bill Lee (5-3) L: Ron Schueler (6-5) S: Jim Willoughby (2) | Second | 2 out |
| Sunday, August 28 |
| » Defeated Twins (73-58), 6-5 | Fenway Park (39-25) | 74-53 | Won 2 |
| » W: Mike Paxton (7-4) L: Ron Schueler (6-6) S: Bill Campbell (22) | Second | 2 out |
| Monday, August 29 |
| » Lost to Athletics (51-77), 8-7 | Fenway Park (39-26) | 74-54 | |
| » W: Doug Bair (3-2) L: Bill Campbell (12-9) | Second | 3 out |
| Future Red Sox Steve Lomasney is born in Melrose, MA. |
| Tuesday, August 30 |
| » Defeated Athletics (51-78), 7-2 | Fenway Park (40-26) | 75-54 | |
| » W: Luis Tiant (9-8) L: Rick Langford (8-15) S: Reggie Cleveland (1) | Second | 3 out |
| Wednesday, August 31 |
| » Lost to Indians (62-70), 4-3 | Fenway Park (40-27) | 75-55 | |
| » W: Jim Kern (7-8) L: Bob Stanley (6-7) | Second | 4 out |
| Thursday, September 1 |
| » Defeated Indians (62-71), 3-1 | Fenway Park (41-27) | 76-55 | |
| » W: Bill Lee (6-3) L: Dennis Eckersley (13-11) S: Reggie Cleveland (2) | Second | 3½ out |
| Friday, September 2 |
| » Lost to Rangers (74-58), 6-4 | Arlington Stadium (1-2) | 76-56 | |
| » W: Bert Blyleven (13-11) L: Fergie Jenkins (10-9) S: Roger Moret (2) | Third | 4½ out |
| » Major-league debuts: Pat Putnam (Rangers) |
| Saturday, September 3 |
| » Defeated Rangers (74-59), 2-1 | Arlington Stadium (2-2) | 77-56 | |
| » W: Mike Paxton (8-4) L: Dock Ellis (7-12) S: Bill Campbell (23) | Second | 4½ out |
| Sunday, September 4 |
| » Defeated Rangers (74-60), 8-4 | Arlington Stadium (3-2) | 78-56 | Won 2 |
| » W: Rick Wise (10-5) L: Gaylord Perry (12-11) S: Bill Campbell (24) | Second | 4½ out |
| Future Red Sox Sun-Woo Kim is born in Inchon, South Korea. |
| Monday, September 5 |
| » Defeated Blue Jays (45-88), 8-0 | Exhibition Stadium (3-1) | 79-56 | Won 3 |
| » W: Don Aase (4-1) L: Jeff Byrd (2-9) | Second | 2½ out |
| » Defeated Blue Jays (45-89), 6-0 | Exhibition Stadium (4-1) | 80-56 | Won 4 |
| » W: Reggie Cleveland (9-7) L: Jim Clancy (2-6) | Second | 2½ out |
| Tuesday, September 6 |
| » Defeated Blue Jays (45-90), 11-2 | Exhibition Stadium (5-1) | 81-56 | Won 5 |
| » W: Bill Lee (7-3) L: Mike Darr (0-1) | Second | 2½ out |
| » Major-league debuts: Mike Darr (Blue Jays) Bo Diaz (Red Sox) |
| Wednesday, September 7 |
| » Lost to Blue Jays (46-90), 3-2 | Exhibition Stadium (5-2) | 81-57 | |
| » W: Dave Lemanczyk (11-13) L: Fergie Jenkins (10-10) | Second | 3½ out |
| Thursday, September 8 |
| » Defeated Blue Jays (46-91), 7-2 | Exhibition Stadium (6-2) | 82-57 | |
| » W: Mike Paxton (9-4) L: Jesse Jefferson (8-15) | Second | 3½ out |
| Friday, September 9 |
| » Defeated Tigers (67-74), 5-1 | Fenway Park (42-27) | 83-57 | Won 2 |
| » W: Luis Tiant (10-8) L: Dave Rozema (15-7) S: Bill Campbell (25) | Second | 3 out |
| » Defeated Tigers (67-75), 8-6 | Fenway Park (43-27) | 84-57 | Won 3 |
| » W: Rick Wise (11-5) L: Vern Ruhle (3-5) S: Bill Campbell (26) | Second | 3 out |
| » Major-league debuts: Alan Trammell and Lou Whitaker (Tigers) |
| Saturday, September 10 |
| » Defeated Tigers (67-76), 7-1 | Fenway Park (44-27) | 85-57 | Won 4 |
| » W: Don Aase (5-1) L: Milt Wilcox (6-1) | Second | 2 out |
| Sunday, September 11 |
| » Defeated Tigers (67-77), 6-2 | Fenway Park (45-27) | 86-57 | Won 5 |
| » W: Bill Lee (8-3) L: Fernando Arroyo (7-16) | Second | 1½ out |
| Tuesday, September 13 |
| » Lost to Yankees (89-56), 4-2 | Yankee Stadium (1-5) | 86-58 | |
| » W: Ron Guidry (14-6) L: Mike Paxton (9-5) | Second | 2½ out |
| Wednesday, September 14 |
| » Lost to Yankees (90-56), 2-0 | Yankee Stadium (1-6) | 86-59 | Lost 2 |
| » W: Ed Figueroa (15-9) L: Reggie Cleveland (9-8) | Third | 3½ out |
| Thursday, September 15 |
| » Defeated Yankees (90-57), 7-3 | Yankee Stadium (2-6) | 87-59 | |
| » W: Luis Tiant (11-8) L: Sparky Lyle (12-5) | Second | 2½ out |
| Friday, September 16 |
| » Lost to Orioles (88-59), 6-1 | Memorial Stadium (4-1) | 87-60 | |
| » W: Jim Palmer (17-11) L: Don Aase (5-2) | Third | 3½ out |
| Saturday, September 17 |
| » Lost to Orioles (89-59), 11-2 | Memorial Stadium (4-2) | 87-61 | Lost 2 |
| » W: Dennis Martinez (14-7) L: Bill Lee (8-4) | Third | 4½ out |
| Sunday, September 18 |
| » Defeated Orioles (89-60), 10-4 | Memorial Stadium (5-2) | 88-61 | |
| » W: Bob Stanley (7-7) L: Scott McGregor (3-4) S: Bill Campbell (27) | Third | 4½ out |
| » Major-league debuts: Ted Cox (Red Sox) |
| Monday, September 19 |
| » Defeated Yankees (93-58), 6-3 | Fenway Park (46-27) | 89-61 | Won 2 |
| » W: Reggie Cleveland (10-8) L: Ed Figueroa (15-10) | Second | 3½ out |
| Wednesday, September 21 |
| » Defeated Yankees (93-59), 3-2 | Fenway Park (47-27) | 90-61 | Won 3 |
| » W: Jim Willoughby (6-0) L: Mike Torrez (16-13) S: Bill Campbell (28) | Third | 2½ out |
| Thursday, September 22 |
| » Lost to Tigers (72-81), 5-4 | Tiger Stadium (0-4) | 90-62 | |
| » W: Fernando Arroyo (8-17) L: Jim Willoughby (6-1) S: Steve Foucault (13) | Third | 3 out |
| Friday, September 23 |
| » Defeated Tigers (72-82), 5-1 | Tiger Stadium (1-4) | 91-62 | |
| » W: Bill Lee (9-4) L: Bob Sykes (5-7) | Third | 3 out |
| Saturday, September 24 |
| » Defeated Tigers (72-83), 6-2 | Tiger Stadium (2-4) | 92-62 | Won 2 |
| » W: Mike Paxton (10-5) L: Milt Wilcox (6-2) S: Bill Campbell (29) | Third | 2½ out |
| Sunday, September 25 |
| » Defeated Tigers (72-84), 12-5 | Tiger Stadium (3-4) | 93-62 | Won 3 |
| » W: Reggie Cleveland (11-8) L: Ed Glynn (2-1) | Second | 3 out |
| Tuesday, September 27 |
| » Defeated Blue Jays (52-104), 6-5 | Fenway Park (48-27) | 94-62 | Won 4 |
| » W: Don Aase (6-2) L: Jeff Byrd (2-13) S: Bill Campbell (30) | Second | 3 out |
| » Defeated Blue Jays (52-105), 5-1 | Fenway Park (49-27) | 95-62 | Won 5 |
| » W: Luis Tiant (12-8) L: Dave Lemanczyk (12-16) S: Bill Campbell (31) | Second | 3 out |
| Wednesday, September 28 |
| » Lost to Blue Jays (53-105), 3-2 | Fenway Park (49-28) | 95-63 | |
| » W: Pete Vuckovich (7-7) L: Bill Lee (9-5) | Second | 4 out |
| Thursday, September 29 |
| » Defeated Blue Jays (53-106), 7-3 | Fenway Park (50-28) | 96-63 | |
| » W: Bob Stanley (8-7) L: Jerry Garvin (10-18) | Second | 3 out |
| Friday, September 30 |
| » Defeated Orioles (96-64), 11-10 | Fenway Park (51-28) | 97-63 | Won 2 |
| » W: Bill Campbell (13-9) L: Scott McGregor (3-5) S: Bob Stanley (3) | Second | 2 out |
| Former Red Sox Del Pratt dies in Texas City, TX at the age of 90. |
| Saturday, October 1 |
| » Lost to Orioles (97-64), 8-7 | Fenway Park (51-29) | 97-64 | |
| » W: Mike Flanagan (15-10) L: Jim Willoughby (6-2) S: Nelson Briles (2) | Second | 2 out |
| Friday, November 4 |
| Former Red Sox Pinky Pittenger dies in Ft.Lauderdale, FL at the age of 79. |
| Wednesday, November 9 |
| Former Red Sox Fred Haney dies in Beverly Hills, CA at the age of 80. |
| Wednesday, December 21 |
| Future Red Sox Freddy Sanchez is born in Hollywood, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |