| Saturday, January 1 |
| Former Cardinal Danny Frisella dies in Phoenix, AZ at the age of 31. |
| Monday, January 3 |
| Future Cardinal Mike Crudale is born in San Diego, CA. |
| Tuesday, January 11 |
| Former Cardinal Tex Carleton dies in Fort Worth, TX at the age of 71. |
| Saturday, January 29 |
| Former Cardinal Hod Ford dies in Winchester, MA at the age of 80. |
| Tuesday, February 15 |
| Former Cardinal Diomedes Olivo dies in Santo Domingo, D.R. at the age of 59. |
| Saturday, February 19 |
| Former Cardinal Mike Gonzales dies in Havana, Cuba at the age of 87. |
| Monday, February 21 |
| Future Cardinal Chad Hutchinson is born in San Diego, CA. |
| Wednesday, April 6 |
| » Major-league debuts: Jose Baez (Mariners) |
| Thursday, April 7 |
| » Defeated Pirates (0-1), 12-6 | Three Rivers Stadium (1-0) | 1-0 | |
| » W: John Denny (1-0) L: Jerry Reuss (0-1) | First | -- |
| Saturday, April 9 |
| » Defeated Pirates (0-2), 8-2 | Three Rivers Stadium (2-0) | 2-0 | Won 2 |
| » W: Bob Forsch (1-0) L: Bruce Kison (0-1) | First | -- |
| Sunday, April 10 |
| » Defeated Pirates (0-3), 8-7 | Three Rivers Stadium (3-0) | 3-0 | Won 3 |
| » W: Clay Carroll (1-0) L: Jim Rooker (0-1) S: John Urrea (1) | First | -- |
| » Major-league debuts: John Urrea (Cardinals) |
| Tuesday, April 12 |
| » Lost to Mets (3-1), 4-0 | Shea Stadium (0-1) | 3-1 | |
| » W: Tom Seaver (2-0) L: Eric Rasmussen (0-1) | First | -- |
| Wednesday, April 13 |
| » Defeated Mets (3-2), 7-3 | Shea Stadium (1-1) | 4-1 | |
| » W: John Denny (2-0) L: Craig Swan (0-1) | First | -- |
| Thursday, April 14 |
| » Defeated Mets (3-3), 4-1 | Shea Stadium (2-1) | 5-1 | Won 2 |
| » W: Bob Forsch (2-0) L: Jerry Koosman (0-1) S: John Urrea (2) | First | -- |
| Friday, April 15 |
| » Lost to Pirates (3-3), 7-0 | Busch Stadium II (0-1) | 5-2 | |
| » W: Jim Rooker (1-1) L: Pete Falcone (0-1) | First | -- |
| Saturday, April 16 |
| » Lost to Pirates (4-3), 3-1 | Busch Stadium II (0-2) | 5-3 | Lost 2 |
| » W: John Candelaria (1-0) L: Eric Rasmussen (0-2) S: Rich Gossage (1) | First | -- |
| Sunday, April 17 |
| » Defeated Pirates (4-4), 4-3 | Busch Stadium II (1-2) | 6-3 | |
| » W: John Denny (3-0) L: Jerry Reuss (0-2) S: John Urrea (3) | First | -- |
| Monday, April 18 |
| » Defeated Mets (5-5), 3-2 | Busch Stadium II (2-2) | 7-3 | Won 2 |
| » W: Bob Forsch (3-0) L: Craig Swan (0-2) S: Al Hrabosky (1) | First | -- |
| Tuesday, April 19 |
| » Lost to Mets (6-5), 5-2 | Busch Stadium II (2-3) | 7-4 | |
| » W: Jerry Koosman (1-1) L: Pete Falcone (0-2) S: Skip Lockwood (2) | Second | 1 out |
| Wednesday, April 20 |
| » Defeated Mets (6-6), 4-2 | Busch Stadium II (3-3) | 8-4 | |
| » W: Eric Rasmussen (1-2) L: Jon Matlack (0-2) | First | -- |
| Friday, April 22 |
| » Defeated Phillies (3-7), 10-1 | Veteran's Stadium (1-0) | 9-4 | Won 2 |
| » W: John Denny (4-0) L: Wayne Twitchell (0-2) | First | -- |
| Saturday, April 23 |
| » Lost to Phillies (4-7), 11-1 | Veteran's Stadium (1-1) | 9-5 | |
| » W: Randy Lerch (2-1) L: Bob Forsch (3-1) | First | -- |
| Sunday, April 24 |
| » Lost to Phillies (5-7), 6-3 | Veteran's Stadium (1-2) | 9-6 | Lost 2 |
| » W: Steve Carlton (2-1) L: Pete Falcone (0-3) | First | -- |
| Tuesday, April 26 |
| » Lost to Cubs (7-6), 4-1 | Wrigley Field (0-1) | 9-7 | Lost 3 |
| » W: Rick Reuschel (2-1) L: Eric Rasmussen (1-3) | Second | 1 out |
| Wednesday, April 27 |
| » Defeated Cubs (7-7), 21-3 | Wrigley Field (1-1) | 10-7 | |
| » W: John Denny (5-0) L: Mike Krukow (0-2) | Second | 1 out |
| Friday, April 29 |
| » Defeated Braves (8-11), 5-2 | Busch Stadium II (4-3) | 11-7 | Won 2 |
| » W: Bob Forsch (4-1) L: Phil Niekro (0-4) S: Al Hrabosky (2) | First | -- |
| Saturday, April 30 |
| » Defeated Braves (8-12), 5-4 | Busch Stadium II (5-3) | 12-7 | Won 3 |
| » W: John Urrea (1-0) L: Rick Camp (1-1) | First | -- |
| Sunday, May 1 |
| » Defeated Braves (8-13), 8-0 | Busch Stadium II (6-3) | 13-7 | Won 4 |
| » W: Eric Rasmussen (2-3) L: Dick Ruthven (3-3) | First | -- |
| Monday, May 2 |
| » Lost to Reds (10-11), 3-2 | Riverfront Stadium (0-1) | 13-8 | |
| » W: Rawly Eastwick (1-2) L: John Urrea (1-1) | Second | 1 out |
| Wednesday, May 4 |
| » Defeated Reds (10-12), 8-1 | Riverfront Stadium (1-1) | 14-8 | |
| » W: Bob Forsch (5-1) L: Woodie Fryman (2-3) | Second | ½ out |
| Friday, May 6 |
| » Defeated Astros (10-15), 4-1 | Busch Stadium II (7-3) | 15-8 | Won 2 |
| » W: Pete Falcone (1-3) L: Bo McLaughlin (0-1) S: Al Hrabosky (3) | Second | ½ out |
| Saturday, May 7 |
| » Lost to Astros (11-15), 3-1 | Busch Stadium II (7-4) | 15-9 | |
| » W: Joe Sambito (3-1) L: John Urrea (1-2) | Second | 1½ out |
| Sunday, May 8 |
| » Defeated Astros (11-16), 2-1 | Busch Stadium II (8-4) | 16-9 | |
| » W: Buddy Schultz (1-0) L: Mark Lemongello (0-4) S: Clay Carroll (1) | Second | 1½ out |
| Monday, May 9 |
| » Defeated Reds (10-16), 6-5 | Busch Stadium II (9-4) | 17-9 | Won 2 |
| » W: Al Hrabosky (1-0) L: Dale Murray (0-1) | Second | 1 out |
| Tuesday, May 10 |
| » Lost to Reds (11-16), 2-1 | Busch Stadium II (9-5) | 17-10 | |
| » W: Gary Nolan (1-0) L: Pete Falcone (1-4) S: Rawly Eastwick (5) | Second | 2½ out |
| Wednesday, May 11 |
| » Lost to Reds (12-16), 5-1 | Busch Stadium II (9-6) | 17-11 | Lost 2 |
| » W: Jack Billingham (4-2) L: Eric Rasmussen (2-4) S: Mike Caldwell (1) | Second | 3½ out |
| Thursday, May 12 |
| » Defeated Reds (12-17), 10-1 | Busch Stadium II (10-6) | 18-11 | |
| » W: Buddy Schultz (2-0) L: Pat Zachry (2-5) | Second | 2½ out |
| Friday, May 13 |
| » Defeated Braves (9-23), 3-0 | Atlanta-Fulton County Stadium (1-0) | 19-11 | Won 2 |
| » W: Bob Forsch (6-1) L: Don Collins (0-2) S: Al Hrabosky (4) | Second | 1½ out |
| Saturday, May 14 |
| » Defeated Braves (9-24), 7-6 | Atlanta-Fulton County Stadium (2-0) | 20-11 | Won 3 |
| » W: Clay Carroll (2-0) L: Buzz Capra (0-4) S: John Urrea (4) | Second | 1½ out |
| Sunday, May 15 |
| » Lost to Braves (10-24), 15-12 | Atlanta-Fulton County Stadium (2-1) | 20-12 | |
| » W: Rick Camp (2-1) L: Al Hrabosky (1-1) S: Don Collins (1) | Third | 2½ out |
| Tuesday, May 17 |
| » Lost to Astros (14-20), 5-2 | Astrodome (0-1) | 20-13 | Lost 2 |
| » W: Ken Forsch (4-2) L: Eric Rasmussen (2-5) | Third | 3½ out |
| Wednesday, May 18 |
| » Defeated Astros (14-21), 8-4 | Astrodome (1-1) | 21-13 | |
| » W: Buddy Schultz (3-0) L: Mark Lemongello (1-5) | Third | 2½ out |
| Friday, May 20 |
| » Lost to Giants (15-22), 7-5 | Busch Stadium II (10-7) | 21-14 | |
| » W: Gary Lavelle (2-1) L: Al Hrabosky (1-2) S: Randy Moffitt (3) | Third | 3 out |
| Saturday, May 21 |
| » Defeated Giants (15-23), 8-5 | Busch Stadium II (11-7) | 22-14 | |
| » W: John Denny (6-0) L: John Montefusco (2-7) S: Clay Carroll (2) | Third | 2 out |
| Sunday, May 22 |
| » Lost to Giants (16-23), 2-0 | Busch Stadium II (11-8) | 22-15 | |
| » W: Jim Barr (6-4) L: Larry Dierker (0-1) S: Gary Lavelle (4) | Third | 3 out |
| Monday, May 23 |
| » Lost to Giants (17-23), 7-2 | Busch Stadium II (11-9) | 22-16 | Lost 2 |
| » W: Ed Halicki (3-4) L: Eric Rasmussen (2-6) S: Gary Lavelle (5) | Third | 3½ out |
| Former Cardinal Sammy Bohne dies in Palo Alto, CA at the age of 81. |
| Tuesday, May 24 |
| » Defeated Phillies (19-18), 8-5 | Busch Stadium II (12-9) | 23-16 | |
| » W: Bob Forsch (7-1) L: Jim Kaat (0-2) S: Al Hrabosky (5) | Third | 3½ out |
| Wednesday, May 25 |
| » Lost to Phillies (20-18), 2-1 | Busch Stadium II (12-10) | 23-17 | |
| » W: Steve Carlton (6-2) L: Pete Falcone (1-5) S: Tom Underwood (1) | Third | 4 out |
| Thursday, May 26 |
| » Defeated Phillies (20-19), 4-3 | Busch Stadium II (13-10) | 24-17 | |
| » W: Butch Metzger (1-0) L: Ron Reed (2-2) | Third | 3½ out |
| Friday, May 27 |
| » Defeated Expos (15-24), 7-3 | Busch Stadium II (14-10) | 25-17 | Won 2 |
| » W: Larry Dierker (1-1) L: Santo Alcala (1-2) | Third | 2½ out |
| Saturday, May 28 |
| » Defeated Expos (15-25), 7-5 | Busch Stadium II (15-10) | 26-17 | Won 3 |
| » W: Eric Rasmussen (3-6) L: Don Stanhouse (3-7) | Third | 2 out |
| Sunday, May 29 |
| » Lost to Expos (16-25), 14-4 | Busch Stadium II (15-11) | 26-18 | |
| » W: Dan Warthen (2-2) L: Bob Forsch (7-2) | Third | 3 out |
| Monday, May 30 |
| » Defeated Cubs (28-15), 14-0 | Busch Stadium II (16-11) | 27-18 | |
| » W: Pete Falcone (2-5) L: Mike Krukow (4-3) | Third | 2 out |
| Tuesday, May 31 |
| » Defeated Cubs (28-16), 6-0 | Busch Stadium II (17-11) | 28-18 | Won 2 |
| » W: John Denny (7-0) L: Bill Bonham (6-4) | Second | 1 out |
| Wednesday, June 1 |
| » Lost to Cubs (29-16), 4-3 | Busch Stadium II (17-12) | 28-19 | |
| » W: Guillermo Hernandez (2-1) L: Buddy Schultz (3-1) | Third | 2 out |
| Friday, June 3 |
| » Lost to Expos (19-28), 2-0 | Stade Olympique (0-1) | 28-20 | Lost 2 |
| » W: Steve Rogers (7-4) L: Eric Rasmussen (3-7) | Third | 2 out |
| Saturday, June 4 |
| » Lost to Expos (20-28), 8-7 | Stade Olympique (0-2) | 28-21 | Lost 3 |
| » W: Bill Atkinson (3-1) L: John Urrea (1-3) | Third | 3 out |
| Sunday, June 5 |
| » Lost to Expos (21-28), 7-5 | Stade Olympique (0-3) | 28-22 | Lost 4 |
| » W: Don Stanhouse (4-7) L: Clay Carroll (2-1) S: Joe Kerrigan (3) | Third | 3 out |
| Monday, June 6 |
| » Defeated Padres (25-32), 4-3 | Busch Stadium II (18-12) | 29-22 | |
| » W: Clay Carroll (3-1) L: Dave Tomlin (1-3) | Third | 3 out |
| Tuesday, June 7 |
| » Lost to Padres (26-32), 9-5 | Busch Stadium II (18-13) | 29-23 | |
| » W: Bob Owchinko (1-0) L: Larry Dierker (1-2) S: Rollie Fingers (14) | Third | 4 out |
| Wednesday, June 8 |
| » Defeated Padres (26-33), 3-0 | Busch Stadium II (19-13) | 30-23 | |
| » W: Eric Rasmussen (4-7) L: Randy Jones (4-6) | Third | 3 out |
| Thursday, June 9 |
| » Defeated Dodgers (37-19), 6-3 | Busch Stadium II (20-13) | 31-23 | Won 2 |
| » W: Bob Forsch (8-2) L: Rick Rhoden (8-3) S: Al Hrabosky (6) | Third | 3 out |
| Friday, June 10 |
| » Defeated Dodgers (37-20), 8-7 | Busch Stadium II (21-13) | 32-23 | Won 3 |
| » W: Clay Carroll (4-1) L: Stan Wall (1-2) | Third | 3 out |
| Saturday, June 11 |
| » Lost to Dodgers (38-20), 9-8 | Busch Stadium II (21-14) | 32-24 | |
| » W: Mike Garman (3-0) L: John Denny (7-1) S: Charlie Hough (16) | Third | 4 out |
| Sunday, June 12 |
| » Defeated Dodgers (38-21), 5-2 | Busch Stadium II (22-14) | 33-24 | |
| » W: Eric Rasmussen (5-7) L: Tommy John (6-4) | Third | 4 out |
| Tuesday, June 14 |
| » Lost to Giants (27-34), 7-1 | Candlestick Park (0-1) | 33-25 | |
| » W: Ed Halicki (6-5) L: Bob Forsch (8-3) | Third | 5 out |
| Wednesday, June 15 |
| » Defeated Giants (27-35), 9-6 | Candlestick Park (1-1) | 34-25 | |
| » W: John Urrea (2-3) L: Randy Moffitt (1-4) | Second | 5 out |
| Thursday, June 16 |
| » Lost to Giants (28-35), 5-1 | Candlestick Park (1-2) | 34-26 | |
| » W: Jim Barr (8-5) L: Larry Dierker (1-3) | Second | 5 out |
| Friday, June 17 |
| » Lost to Padres (29-38), 4-3 | San Diego/Jack Murphy Stadium (0-1) | 34-27 | Lost 2 |
| » W: John D'Acquisto (1-1) L: John Denny (7-2) S: Rollie Fingers (16) | Second | 6 out |
| Saturday, June 18 |
| » Lost to Padres (30-38), 4-1 | San Diego/Jack Murphy Stadium (0-2) | 34-28 | Lost 3 |
| » W: Tom Griffin (5-4) L: Eric Rasmussen (5-8) S: Dave Tomlin (3) | Second | 6 out |
| Sunday, June 19 |
| » Lost to Padres (31-38), 6-2 | San Diego/Jack Murphy Stadium (0-3) | 34-29 | Lost 4 |
| » W: Bob Owchinko (2-1) L: Bob Forsch (8-4) | Third | 6 out |
| Monday, June 20 |
| » Lost to Dodgers (44-22), 9-3 | Dodger Stadium (0-1) | 34-30 | Lost 5 |
| » W: Rick Rhoden (10-3) L: Pete Falcone (2-6) | Fourth | 7 out |
| Tuesday, June 21 |
| » Defeated Dodgers (44-23), 4-3 | Dodger Stadium (1-1) | 35-30 | |
| » W: Al Hrabosky (2-2) L: Charlie Hough (4-5) | Fourth | 7 out |
| Wednesday, June 22 |
| » Lost to Dodgers (45-23), 12-1 | Dodger Stadium (1-2) | 35-31 | |
| » W: Burt Hooton (5-3) L: Tom Underwood (3-3) | Fourth | 8 out |
| Friday, June 24 |
| » Defeated Phillies (36-30), 7-1 | Busch Stadium II (23-14) | 36-31 | |
| » W: Eric Rasmussen (6-8) L: Jim Lonborg (1-1) | Fourth | 8 out |
| Saturday, June 25 |
| » Defeated Phillies (36-31), 3-2 | Busch Stadium II (24-14) | 37-31 | Won 2 |
| » W: Bob Forsch (9-4) L: Steve Carlton (9-4) S: Rawly Eastwick (8) | Third | 8 out |
| Sunday, June 26 |
| » Lost to Phillies (37-31), 2-0 | Busch Stadium II (24-15) | 37-32 | |
| » W: Jim Kaat (3-5) L: Larry Dierker (1-4) S: Gene Garber (9) | Fourth | 9 out |
| Former Cardinal Jack Berly dies in Houston, TX at the age of 75. |
| Monday, June 27 |
| » Defeated Pirates (38-31), 6-1 | Busch Stadium II (25-15) | 38-32 | |
| » W: Pete Falcone (3-6) L: Jerry Reuss (3-8) | Third | 9 out |
| Tuesday, June 28 |
| » Defeated Pirates (38-32), 6-1 | Busch Stadium II (26-15) | 39-32 | Won 2 |
| » W: Buddy Schultz (4-1) L: Terry Forster (1-2) | Third | 8½ out |
| » Defeated Pirates (38-33), 13-3 | Busch Stadium II (27-15) | 40-32 | Won 3 |
| » W: Tom Underwood (4-3) L: Grant Jackson (0-2) | Third | 8½ out |
| Wednesday, June 29 |
| » Lost to Pirates (39-33), 9-1 | Busch Stadium II (27-16) | 40-33 | |
| » W: Bruce Kison (6-3) L: Eric Rasmussen (6-9) | Third | 8½ out |
| Thursday, June 30 |
| » Defeated Cubs (47-24), 2-1 | Busch Stadium II (28-16) | 41-33 | |
| » W: Rawly Eastwick (3-2) L: Guillermo Hernandez (3-3) | Third | 7½ out |
| Friday, July 1 |
| » Defeated Cubs (47-25), 3-1 | Busch Stadium II (29-16) | 42-33 | Won 2 |
| » W: Larry Dierker (2-4) L: Mike Krukow (7-5) S: Rawly Eastwick (9) | Third | 6½ out |
| Saturday, July 2 |
| » Defeated Cubs (47-26), 10-3 | Busch Stadium II (30-16) | 43-33 | Won 3 |
| » W: Pete Falcone (4-6) L: Bill Bonham (8-7) | Third | 5½ out |
| Sunday, July 3 |
| » Lost to Cubs (48-26), 4-0 | Busch Stadium II (30-17) | 43-34 | |
| » W: Bruce Sutter (4-1) L: Eric Rasmussen (6-10) | Third | 6½ out |
| Monday, July 4 |
| » Lost to Pirates (40-37), 5-2 | Three Rivers Stadium (3-1) | 43-35 | Lost 2 |
| » W: Jim Rooker (6-5) L: Tom Underwood (4-4) S: Rich Gossage (14) | Third | 6½ out |
| » Lost to Pirates (41-37), 4-3 | Three Rivers Stadium (3-2) | 43-36 | Lost 3 |
| » W: Kent Tekulve (6-1) L: Rawly Eastwick (3-3) | Third | 6½ out |
| Tuesday, July 5 |
| » Defeated Pirates (41-38), 7-3 | Three Rivers Stadium (4-2) | 44-36 | |
| » W: Bob Forsch (10-4) L: John Candelaria (8-3) | Third | 5½ out |
| Wednesday, July 6 |
| » Lost to Pirates (42-38), 11-8 | Three Rivers Stadium (4-3) | 44-37 | |
| » W: Kent Tekulve (7-1) L: Al Hrabosky (2-3) | Third | 6½ out |
| Thursday, July 7 |
| » Lost to Cubs (50-29), 2-0 | Wrigley Field (1-2) | 44-38 | Lost 2 |
| » W: Rick Reuschel (12-2) L: Larry Dierker (2-5) | Third | 7½ out |
| Friday, July 8 |
| » Lost to Cubs (51-29), 7-6 | Wrigley Field (1-3) | 44-39 | Lost 3 |
| » W: Paul Reuschel (3-1) L: Rawly Eastwick (3-4) S: Bruce Sutter (23) | Fourth | 8½ out |
| Saturday, July 9 |
| » Defeated Cubs (51-30), 4-3 | Wrigley Field (2-3) | 45-39 | |
| » W: Tom Underwood (5-4) L: Steve Renko (0-1) S: Clay Carroll (3) | Fourth | 7½ out |
| Sunday, July 10 |
| » Defeated Cubs (51-31), 8-3 | Wrigley Field (3-3) | 46-39 | Won 2 |
| » W: Bob Forsch (11-4) L: Bill Bonham (9-8) | Fourth | 7½ out |
| » Lost to Cubs (52-31), 4-3 | Wrigley Field (3-4) | 46-40 | |
| » W: Bruce Sutter (5-1) L: Al Hrabosky (2-4) | Fourth | 7½ out |
| Tuesday, July 12 |
| » Lost to Phillies (48-36), 5-4 | Veteran's Stadium (1-3) | 46-41 | Lost 2 |
| » W: Randy Lerch (6-2) L: Rawly Eastwick (3-5) | Fourth | 7½ out |
| Wednesday, July 13 |
| » Lost to Phillies (49-36), 5-2 | Veteran's Stadium (1-4) | 46-42 | Lost 3 |
| » W: Steve Carlton (12-4) L: Tom Underwood (5-5) S: Tug McGraw (3) | Fourth | 8 out |
| Thursday, July 14 |
| » Defeated Phillies (49-37), 7-6 | Veteran's Stadium (2-4) | 47-42 | |
| » W: Rawly Eastwick (4-5) L: Tug McGraw (3-1) S: Al Hrabosky (7) | Fourth | 7½ out |
| Friday, July 15 |
| » Lost to Expos (40-47), 7-6 | Stade Olympique (0-4) | 47-43 | |
| » W: Bill Atkinson (5-2) L: Tom Underwood (5-6) | Fourth | 7 out |
| Saturday, July 16 |
| » Lost to Expos (41-47), 3-0 | Stade Olympique (0-5) | 47-44 | Lost 2 |
| » W: Stan Bahnsen (6-4) L: Larry Dierker (2-6) | Fourth | 8 out |
| Former Cardinal Milt Stock dies in Fairhope, AL at the age of 85. |
| Sunday, July 17 |
| » Lost to Expos (42-47), 8-7 | Stade Olympique (0-6) | 47-45 | Lost 3 |
| » W: Bill Atkinson (6-2) L: Rawly Eastwick (4-6) | Fourth | 8 out |
| Thursday, July 21 |
| » Defeated Astros (43-51), 4-0 | Busch Stadium II (31-17) | 48-45 | |
| » W: Bob Forsch (12-4) L: J.R. Richard (9-7) | Fourth | 8 out |
| Friday, July 22 |
| » Lost to Astros (44-51), 4-2 | Busch Stadium II (31-18) | 48-46 | |
| » W: Mark Lemongello (3-11) L: Clay Carroll (4-2) | Fourth | 9 out |
| Saturday, July 23 |
| » Defeated Astros (44-52), 4-3 | Busch Stadium II (32-18) | 49-46 | |
| » W: Rawly Eastwick (5-6) L: Bo McLaughlin (3-4) | Fourth | 8 out |
| Sunday, July 24 |
| » Defeated Reds (48-45), 3-0 | Busch Stadium II (33-18) | 50-46 | Won 2 |
| » W: Eric Rasmussen (7-10) L: Paul Moskau (1-2) | Fourth | 6½ out |
| Monday, July 25 |
| » Defeated Reds (48-46), 9-8 | Busch Stadium II (34-18) | 51-46 | Won 3 |
| » W: Buddy Schultz (5-1) L: Jack Billingham (8-7) S: Butch Metzger (1) | Fourth | 6½ out |
| Tuesday, July 26 |
| » Defeated Braves (35-62), 4-2 | Busch Stadium II (35-18) | 52-46 | Won 4 |
| » W: Bob Forsch (13-4) L: Dick Ruthven (3-7) S: Buddy Schultz (1) | Fourth | 6½ out |
| Wednesday, July 27 |
| » Defeated Braves (35-63), 5-3 | Busch Stadium II (36-18) | 53-46 | Won 5 |
| » W: Al Hrabosky (3-4) L: Rick Camp (6-3) S: Butch Metzger (2) | Fourth | 6 out |
| Thursday, July 28 |
| » Defeated Braves (35-64), 3-0 | Busch Stadium II (37-18) | 54-46 | Won 6 |
| » W: John Urrea (3-3) L: Buzz Capra (2-8) | Fourth | 6 out |
| Friday, July 29 |
| » Lost to Reds (50-49), 6-5 | Riverfront Stadium (1-2) | 54-47 | |
| » W: Paul Moskau (2-2) L: Rawly Eastwick (5-7) S: Pedro Borbon (8) | Fourth | 5½ out |
| » Defeated Reds (50-50), 10-3 | Riverfront Stadium (2-2) | 55-47 | |
| » W: Eric Rasmussen (8-10) L: Jack Billingham (8-9) | Fourth | 5½ out |
| Saturday, July 30 |
| » Defeated Reds (50-51), 4-1 | Riverfront Stadium (3-2) | 56-47 | Won 2 |
| » W: Butch Metzger (2-0) L: Fred Norman (9-8) S: Al Hrabosky (8) | Fourth | 4½ out |
| Sunday, July 31 |
| » Lost to Reds (51-51), 6-2 | Riverfront Stadium (3-3) | 56-48 | |
| » W: Doug Capilla (3-3) L: Bob Forsch (13-5) S: Pedro Borbon (9) | Fourth | 5½ out |
| Monday, August 1 |
| » Defeated Braves (37-66), 6-5 | Atlanta-Fulton County Stadium (3-1) | 57-48 | |
| » W: Tom Underwood (6-6) L: Max Leon (4-4) S: Butch Metzger (3) | Fourth | 4½ out |
| Tuesday, August 2 |
| » Defeated Braves (37-67), 6-4 | Atlanta-Fulton County Stadium (4-1) | 58-48 | Won 2 |
| » W: Butch Metzger (3-0) L: Phil Niekro (10-13) S: Clay Carroll (4) | Fourth | 4½ out |
| Wednesday, August 3 |
| » Defeated Braves (37-68), 5-1 | Atlanta-Fulton County Stadium (5-1) | 59-48 | Won 3 |
| » W: Eric Rasmussen (9-10) L: Dick Ruthven (3-8) | Fourth | 3½ out |
| Friday, August 5 |
| » Lost to Astros (51-58), 5-4 | Astrodome (1-2) | 59-49 | |
| » W: J.R. Richard (10-9) L: John Denny (7-3) S: Joe Sambito (4) | Fourth | 4 out |
| Saturday, August 6 |
| » Defeated Astros (51-59), 3-1 | Astrodome (2-2) | 60-49 | |
| » W: Bob Forsch (14-5) L: Mark Lemongello (4-13) S: Butch Metzger (4) | Fourth | 4½ out |
| » Lost to Astros (52-59), 4-1 | Astrodome (2-3) | 60-50 | |
| » W: Tom Dixon (1-0) L: Tom Underwood (6-7) | Fourth | 4½ out |
| Sunday, August 7 |
| » Defeated Astros (52-60), 5-2 | Astrodome (3-3) | 61-50 | |
| » W: John Urrea (4-3) L: Dan Larson (0-6) S: Butch Metzger (5) | Fourth | 4½ out |
| Monday, August 8 |
| » Defeated Mets (46-63), 4-2 | Shea Stadium (3-1) | 62-50 | Won 2 |
| » W: Al Hrabosky (4-4) L: Jerry Koosman (8-13) | Fourth | 4 out |
| Tuesday, August 9 |
| » Lost to Mets (47-63), 4-1 | Shea Stadium (3-2) | 62-51 | |
| » W: Nino Espinosa (6-8) L: John Denny (7-4) | Fourth | 4½ out |
| Wednesday, August 10 |
| » Defeated Mets (47-64), 3-1 | Shea Stadium (4-2) | 63-51 | |
| » W: Tom Underwood (7-7) L: Craig Swan (7-7) S: Butch Metzger (6) | Fourth | 5 out |
| Friday, August 12 |
| » Defeated Expos (52-63), 2-1 | Busch Stadium II (38-18) | 64-51 | Won 2 |
| » W: Al Hrabosky (5-4) L: Will McEnaney (2-5) | Fourth | 5½ out |
| Saturday, August 13 |
| » Defeated Expos (52-64), 1-0 | Busch Stadium II (39-18) | 65-51 | Won 3 |
| » W: Butch Metzger (4-0) L: Don Stanhouse (8-9) | Fourth | 5½ out |
| Sunday, August 14 |
| » Lost to Expos (53-64), 6-2 | Busch Stadium II (39-19) | 65-52 | |
| » W: Steve Rogers (13-11) L: Eric Rasmussen (9-11) | Fourth | 7 out |
| Monday, August 15 |
| » Lost to Mets (48-69), 7-4 | Busch Stadium II (39-20) | 65-53 | Lost 2 |
| » W: Craig Swan (8-7) L: John Denny (7-5) S: Bob Apodaca (4) | Fourth | 7½ out |
| Tuesday, August 16 |
| » Lost to Mets (49-69), 5-1 | Busch Stadium II (39-21) | 65-54 | Lost 3 |
| » W: Pat Zachry (6-12) L: Tom Underwood (7-8) | Fourth | 8½ out |
| Wednesday, August 17 |
| » Defeated Mets (49-70), 2-0 | Busch Stadium II (40-21) | 66-54 | |
| » W: Bob Forsch (15-5) L: Jerry Koosman (8-15) | Fourth | 7½ out |
| Friday, August 19 |
| » Defeated Padres (54-71), 12-4 | Busch Stadium II (41-21) | 67-54 | Won 2 |
| » W: John Urrea (5-3) L: Dave Freisleben (5-7) | Fourth | 8 out |
| Saturday, August 20 |
| » Defeated Padres (54-72), 7-1 | Busch Stadium II (42-21) | 68-54 | Won 3 |
| » W: Eric Rasmussen (10-11) L: Randy Jones (5-10) | Fourth | 8 out |
| Future Cardinal Josh Pearce is born in Yakima, WA. |
| Sunday, August 21 |
| » Lost to Padres (55-72), 7-0 | Busch Stadium II (42-22) | 68-55 | |
| » W: Bob Owchinko (6-8) L: Tom Underwood (7-9) | Fourth | 9 out |
| Monday, August 22 |
| » Defeated Dodgers (74-50), 8-6 | Busch Stadium II (43-22) | 69-55 | |
| » W: Al Hrabosky (6-4) L: Charlie Hough (5-10) | Fourth | 9 out |
| » Major-league debuts: Ken Oberkfell (Cardinals) |
| Tuesday, August 23 |
| » Defeated Dodgers (74-51), 2-1 | Busch Stadium II (44-22) | 70-55 | Won 2 |
| » W: Bob Forsch (16-5) L: Don Sutton (11-8) | Fourth | 9 out |
| Former Cardinal Bubber Jonnard dies in New York, NY at the age of 80. |
| Wednesday, August 24 |
| » Defeated Giants (58-70), 3-2 | Busch Stadium II (45-22) | 71-55 | Won 3 |
| » W: John Urrea (6-3) L: Ed Halicki (11-10) S: Al Hrabosky (9) | Third | 8 out |
| Thursday, August 25 |
| » Lost to Giants (59-70), 4-2 | Busch Stadium II (45-23) | 71-56 | |
| » W: John Montefusco (7-9) L: Butch Metzger (4-1) S: Randy Moffitt (10) | Third | 8 out |
| Friday, August 26 |
| » Lost to Dodgers (76-52), 5-4 | Dodger Stadium (1-3) | 71-57 | Lost 2 |
| » W: Rick Rhoden (15-8) L: Eric Rasmussen (10-12) S: Mike Garman (8) | Fourth | 8 out |
| Saturday, August 27 |
| » Lost to Dodgers (77-52), 4-3 | Dodger Stadium (1-4) | 71-58 | Lost 3 |
| » W: Elias Sosa (1-2) L: Butch Metzger (4-2) | Fourth | 8 out |
| » Major-league debuts: Rafael Landestoy (Dodgers) |
| Sunday, August 28 |
| » Lost to Dodgers (78-52), 11-0 | Dodger Stadium (1-5) | 71-59 | Lost 4 |
| » W: Don Sutton (12-8) L: Bob Forsch (16-6) | Fourth | 8 out |
| Monday, August 29 |
| » Lost to Padres (57-76), 4-3 | San Diego/Jack Murphy Stadium (0-4) | 71-60 | Lost 5 |
| » W: Dave Freisleben (6-7) L: Al Hrabosky (6-5) S: Rollie Fingers (29) | Fourth | 9 out |
| Tuesday, August 30 |
| » Lost to Padres (58-76), 7-4 | San Diego/Jack Murphy Stadium (0-5) | 71-61 | Lost 6 |
| » W: Bob Owchinko (7-9) L: Eric Rasmussen (10-13) S: Dan Spillner (6) | Fourth | 10 out |
| Wednesday, August 31 |
| » Lost to Padres (59-76), 2-1 | San Diego/Jack Murphy Stadium (0-6) | 71-62 | Lost 7 |
| » W: Bob Shirley (9-16) L: Tom Underwood (7-10) S: Rollie Fingers (30) | Fourth | 11 out |
| Friday, September 2 |
| » Defeated Giants (62-73), 6-4 | Candlestick Park (2-2) | 72-62 | |
| » W: Buddy Schultz (6-1) L: Randy Moffitt (3-7) S: Butch Metzger (7) | Fourth | 11 out |
| Saturday, September 3 |
| » Lost to Giants (63-73), 6-5 | Candlestick Park (2-3) | 72-63 | |
| » W: Dave Heaverlo (4-1) L: Pete Falcone (4-7) | Fourth | 12 out |
| Sunday, September 4 |
| » Defeated Giants (63-74), 8-2 | Candlestick Park (3-3) | 73-63 | |
| » W: John Urrea (7-3) L: John Montefusco (7-11) | Third | 11 out |
| Monday, September 5 |
| » Lost to Cubs (74-62), 4-2 | Wrigley Field (3-5) | 73-64 | |
| » W: Dave Roberts (5-11) L: Eric Rasmussen (10-14) | Fourth | 11½ out |
| Tuesday, September 6 |
| » Defeated Cubs (74-63), 3-1 | Wrigley Field (4-5) | 74-64 | |
| » W: Tom Underwood (8-10) L: Guillermo Hernandez (7-6) | Fourth | 10½ out |
| Wednesday, September 7 |
| » Lost to Pirates (80-60), 5-4 | Three Rivers Stadium (4-4) | 74-65 | |
| » W: Terry Forster (4-4) L: John Denny (7-6) S: Kent Tekulve (6) | Fourth | 11½ out |
| Thursday, September 8 |
| » Lost to Pirates (81-60), 9-5 | Three Rivers Stadium (4-5) | 74-66 | Lost 2 |
| » W: Larry Demery (6-4) L: Rawly Eastwick (5-8) S: Rich Gossage (20) | Fourth | 12½ out |
| Friday, September 9 |
| » Lost to Phillies (87-53), 11-4 | Veteran's Stadium (2-5) | 74-67 | Lost 3 |
| » W: Steve Carlton (21-8) L: John Urrea (7-4) | Fourth | 13½ out |
| Saturday, September 10 |
| » Lost to Phillies (88-53), 3-1 | Veteran's Stadium (2-6) | 74-68 | Lost 4 |
| » W: Randy Lerch (8-5) L: Eric Rasmussen (10-15) | Fourth | 14½ out |
| Sunday, September 11 |
| » Lost to Phillies (89-53), 6-5 | Veteran's Stadium (2-7) | 74-69 | Lost 5 |
| » W: Warren Brusstar (5-2) L: John Sutton (0-1) S: Gene Garber (15) | Fourth | 15½ out |
| Monday, September 12 |
| » Defeated Cubs (76-67), 11-9 | Busch Stadium II (46-23) | 75-69 | |
| » W: John Sutton (1-1) L: Bruce Sutter (7-2) | Fourth | 15½ out |
| Tuesday, September 13 |
| » Defeated Cubs (76-68), 3-1 | Busch Stadium II (47-23) | 76-69 | Won 2 |
| » W: Bob Forsch (17-6) L: Ray Burris (13-15) S: Pete Falcone (1) | Third | 14½ out |
| Thursday, September 15 |
| » Lost to Pirates (84-63), 4-3 | Busch Stadium II (47-24) | 76-70 | |
| » W: John Candelaria (17-5) L: Eric Rasmussen (10-16) S: Rich Gossage (22) | Third | 14½ out |
| » Defeated Pirates (84-64), 10-7 | Busch Stadium II (48-24) | 77-70 | |
| » W: John Sutton (2-1) L: Larry Demery (6-5) S: Rawly Eastwick (10) | Third | 14½ out |
| Friday, September 16 |
| » Lost to Phillies (92-55), 12-6 | Busch Stadium II (48-25) | 77-71 | |
| » W: Warren Brusstar (6-2) L: John Denny (7-7) S: Gene Garber (16) | Fourth | 15½ out |
