| Friday, April 9 |
| » Defeated Red Sox (0-1), 1-0 | Memorial Stadium (1-0) | 1-0 | |
| » W: Jim Palmer (1-0) L: Fergie Jenkins (0-1) S: Dyar Miller (1) | First | -- |
| Saturday, April 10 |
| » Defeated Red Sox (0-2), 5-1 | Memorial Stadium (2-0) | 2-0 | Won 2 |
| » W: Ken Holtzman (1-0) L: Tom House (0-1) | First | -- |
| Sunday, April 11 |
| » Lost to Red Sox (1-2), 6-2 | Memorial Stadium (2-1) | 2-1 | |
| » W: Luis Tiant (1-0) L: Mike Cuellar (0-1) | Second | 1 out |
| Monday, April 12 |
| » Lost to Yankees (2-1), 3-0 | Memorial Stadium (2-2) | 2-2 | Lost 2 |
| » W: Catfish Hunter (1-1) L: Ross Grimsley (0-1) | Fourth | 1½ out |
| Tuesday, April 13 |
| » Lost to Yankees (3-1), 7-1 | Memorial Stadium (2-3) | 2-3 | Lost 3 |
| » W: Dock Ellis (1-0) L: Jim Palmer (1-1) | Fifth | 1½ out |
| » Major-league debuts: Andres Mora (Orioles) |
| Saturday, April 17 |
| » Defeated Athletics (3-4), 6-1 | Oakland-Alameda County Stadium (1-0) | 3-3 | |
| » W: Jim Palmer (2-1) L: Mike Torrez (1-2) | Fourth | 2 out |
| Sunday, April 18 |
| » Lost to Athletics (4-4), 2-1 | Oakland-Alameda County Stadium (1-1) | 3-4 | |
| » W: Rollie Fingers (1-0) L: Dyar Miller (0-1) | Fourth | 2 out |
| Monday, April 19 |
| » Lost to Angels (4-6), 9-4 | Anaheim Stadium (0-1) | 3-5 | Lost 2 |
| » W: Frank Tanana (1-1) L: Mike Cuellar (0-2) | Fifth | 2½ out |
| Tuesday, April 20 |
| » Lost to Angels (5-6), 5-0 | Anaheim Stadium (0-2) | 3-6 | Lost 3 |
| » W: Nolan Ryan (2-1) L: Doyle Alexander (0-1) | Fifth | 3½ out |
| Wednesday, April 21 |
| » Defeated Angels (5-7), 5-1 | Anaheim Stadium (1-2) | 4-6 | |
| » W: Jim Palmer (3-1) L: Don Kirkwood (0-2) S: Dyar Miller (2) | Sixth | 3½ out |
| Saturday, April 24 |
| » Lost to Twins (4-7), 2-1 | Metropolitan Stadium (0-1) | 4-7 | |
| » W: Bill Campbell (2-1) L: Grant Jackson (0-1) | Sixth | 4 out |
| Sunday, April 25 |
| » Lost to Twins (5-7), 7-2 | Metropolitan Stadium (0-2) | 4-8 | Lost 2 |
| » W: Tom Burgmeier (1-0) L: Jim Palmer (3-2) | Sixth | 4½ out |
| Tuesday, April 27 |
| » Defeated Angels (5-10), 3-2 | Memorial Stadium (3-3) | 5-8 | |
| » W: Grant Jackson (1-1) L: Dick Drago (0-1) | Fifth | 4½ out |
| Wednesday, April 28 |
| » Defeated Angels (5-11), 4-2 | Memorial Stadium (4-3) | 6-8 | Won 2 |
| » W: Ken Holtzman (2-0) L: Gary Ross (0-3) | Sixth | 4 out |
| Friday, April 30 |
| » Lost to Athletics (9-8), 11-1 | Memorial Stadium (4-4) | 6-9 | |
| » W: Mike Torrez (3-3) L: Jim Palmer (3-3) | Fifth | 5 out |
| Sunday, May 2 |
| » Lost to Athletics (10-8), 6-2 | Memorial Stadium (4-5) | 6-10 | Lost 2 |
| » W: Vida Blue (2-3) L: Ross Grimsley (0-2) | Fifth | 4 out |
| » Defeated Athletics (10-9), 4-3 | Memorial Stadium (5-5) | 7-10 | |
| » W: Wayne Garland (1-0) L: Glenn Abbott (0-1) | Fifth | 4 out |
| Tuesday, May 4 |
| » Lost to White Sox (6-8), 3-1 | Memorial Stadium (5-6) | 7-11 | |
| » W: Wilbur Wood (3-3) L: Ken Holtzman (2-1) | Fifth | 5 out |
| Wednesday, May 5 |
| » Defeated White Sox (6-9), 2-0 | Memorial Stadium (6-6) | 8-11 | |
| » W: Jim Palmer (4-3) L: Rich Gossage (1-2) | Fifth | 5 out |
| Friday, May 7 |
| » Defeated Royals (9-8), 4-3 | Memorial Stadium (7-6) | 9-11 | Won 2 |
| » W: Wayne Garland (2-0) L: Marty Pattin (0-3) | Fifth | 5½ out |
| Saturday, May 8 |
| » Lost to Royals (10-8), 6-3 | Memorial Stadium (7-7) | 9-12 | |
| » W: Dennis Leonard (1-1) L: Ken Holtzman (2-2) S: Doug Bird (2) | Fifth | 6½ out |
| Sunday, May 9 |
| » Lost to Royals (11-8), 7-4 | Memorial Stadium (7-8) | 9-13 | Lost 2 |
| » W: Mark Littell (1-0) L: Jim Palmer (4-4) | Fifth | 6½ out |
| Tuesday, May 11 |
| » Defeated Brewers (10-8), 5-2 | County Stadium (1-0) | 10-13 | |
| » W: Mike Cuellar (1-2) L: Jim Colborn (2-3) S: Wayne Garland (1) | Fifth | 5½ out |
| Wednesday, May 12 |
| » Defeated Brewers (10-9), 8-6 | County Stadium (2-0) | 11-13 | Won 2 |
| » W: Doyle Alexander (1-1) L: Jerry Augustine (0-1) | Fourth | 5½ out |
| Thursday, May 13 |
| » Defeated Brewers (10-10), 5-3 | County Stadium (3-0) | 12-13 | Won 3 |
| » W: Jim Palmer (5-4) L: Bill Travers (2-2) | Fourth | 4½ out |
| Friday, May 14 |
| » Defeated Yankees (16-9), 6-2 | Yankee Stadium (1-0) | 13-13 | Won 4 |
| » W: Ross Grimsley (1-2) L: Catfish Hunter (3-5) S: Grant Jackson (1) | Third | 3½ out |
| Saturday, May 15 |
| » Lost to Yankees (17-9), 7-3 | Yankee Stadium (1-1) | 13-14 | |
| » W: Ed Figueroa (3-2) L: Mike Cuellar (1-3) S: Sparky Lyle (7) | Third | 4½ out |
| Future Oriole Eric DuBose is born in Bradenton, FL. |
| Sunday, May 16 |
| » Defeated Yankees (17-10), 7-0 | Yankee Stadium (2-1) | 14-14 | |
| » W: Ken Holtzman (3-2) L: Dock Ellis (4-1) | Third | 3½ out |
| Monday, May 17 |
| » Defeated Brewers (11-13), 4-3 | Memorial Stadium (8-8) | 15-14 | Won 2 |
| » W: Dyar Miller (1-1) L: Eduardo Rodriguez (1-3) | Second | 3 out |
| Wednesday, May 19 |
| » Defeated Brewers (11-14), 5-3 | Memorial Stadium (9-8) | 16-14 | Won 3 |
| » W: Mike Cuellar (2-3) L: Jim Colborn (2-4) S: Grant Jackson (2) | Second | 3½ out |
| Future Oriole Chris Fussell is born in Oregon, OH. |
| Friday, May 21 |
| » Defeated Tigers (13-16), 8-5 | Memorial Stadium (10-8) | 17-14 | Won 4 |
| » W: Doyle Alexander (2-1) L: Ray Bare (2-4) | Second | 3 out |
| Saturday, May 22 |
| » Defeated Tigers (13-17), 8-4 | Memorial Stadium (11-8) | 18-14 | Won 5 |
| » W: Wayne Garland (3-0) L: Jim Crawford (0-3) | Second | 3 out |
| Sunday, May 23 |
| » Lost to Tigers (14-17), 10-6 | Memorial Stadium (11-9) | 18-15 | |
| » W: John Hiller (2-3) L: Dyar Miller (1-2) | Second | 3 out |
| Monday, May 24 |
| » Lost to Indians (16-19), 4-0 | Memorial Stadium (11-10) | 18-16 | Lost 2 |
| » W: Dennis Eckersley (3-2) L: Mike Cuellar (2-4) | Second | 4 out |
| Tuesday, May 25 |
| » Lost to Indians (17-19), 3-1 | Memorial Stadium (11-11) | 18-17 | Lost 3 |
| » W: Pat Dobson (4-5) L: Jim Palmer (5-5) | Second | 4 out |
| Wednesday, May 26 |
| » Defeated Tigers (14-20), 6-0 | Tiger Stadium (1-0) | 19-17 | |
| » W: Doyle Alexander (3-1) L: Bill Laxton (0-2) | Second | 4½ out |
| » Lost to Tigers (15-20), 6-2 | Tiger Stadium (1-1) | 19-18 | |
| » W: Ray Bare (3-4) L: Ross Grimsley (1-3) S: John Hiller (4) | Second | 4½ out |
| Thursday, May 27 |
| » Defeated Tigers (15-21), 4-3 | Tiger Stadium (2-1) | 20-18 | |
| » W: Ken Holtzman (4-2) L: Joe Coleman (2-4) S: Dyar Miller (3) | Second | 3½ out |
| Friday, May 28 |
| » Defeated Red Sox (18-20), 4-1 | Fenway Park (1-0) | 21-18 | Won 2 |
| » W: Wayne Garland (4-0) L: Reggie Cleveland (3-1) S: Grant Jackson (3) | Second | 3½ out |
| Saturday, May 29 |
| » Defeated Red Sox (18-21), 7-2 | Fenway Park (2-0) | 22-18 | Won 3 |
| » W: Jim Palmer (6-5) L: Luis Tiant (6-3) | Second | 2½ out |
| Future Oriole Jerry Hairston is born in Naperville, IL. |
| Sunday, May 30 |
| » Lost to Red Sox (19-21), 3-1 | Fenway Park (2-1) | 22-19 | |
| » W: Rick Wise (3-3) L: Doyle Alexander (3-2) | Second | 3½ out |
| Monday, May 31 |
| » Lost to Indians (20-21), 4-1 | Cleveland Stadium (0-1) | 22-20 | Lost 2 |
| » W: Jim Kern (3-2) L: Ken Holtzman (4-3) S: Stan Thomas (2) | Second | 5 out |
| » Lost to Indians (21-21), 4-3 | Cleveland Stadium (0-2) | 22-21 | Lost 3 |
| » W: Pat Dobson (5-5) L: Mike Cuellar (2-5) S: Dave LaRoche (5) | Second | 5 out |
| Wednesday, June 2 |
| » Defeated Indians (21-22), 2-0 | Cleveland Stadium (1-2) | 23-21 | |
| » W: Wayne Garland (5-0) L: Tom Buskey (2-3) | Second | 5 out |
| Friday, June 4 |
| » Lost to Twins (22-23), 8-6 | Memorial Stadium (11-12) | 23-22 | |
| » W: Bill Campbell (6-2) L: Mike Flanagan (0-1) | Second | 4½ out |
| Saturday, June 5 |
| » Defeated Twins (22-24), 5-1 | Memorial Stadium (12-12) | 24-22 | |
| » W: Ken Holtzman (5-3) L: Joe Decker (2-4) | Second | 3½ out |
| Sunday, June 6 |
| » Lost to Twins (23-24), 3-2 | Memorial Stadium (12-13) | 24-23 | |
| » W: Bill Singer (5-1) L: Jim Palmer (6-6) | Second | 4½ out |
| » Lost to Twins (24-24), 11-6 | Memorial Stadium (12-14) | 24-24 | Lost 2 |
| » W: Jim Hughes (2-6) L: Mike Cuellar (2-6) S: Bill Campbell (5) | Second | 4½ out |
| Monday, June 7 |
| » Lost to Rangers (28-20), 6-4 | Memorial Stadium (12-15) | 24-25 | Lost 3 |
| » W: Jim Umbarger (6-4) L: Ross Grimsley (1-4) S: Steve Foucault (3) | Second | 5 out |
| Tuesday, June 8 |
| » Lost to Rangers (29-20), 6-3 | Memorial Stadium (12-16) | 24-26 | Lost 4 |
| » W: Fritz Peterson (1-3) L: Doyle Alexander (3-3) S: Steve Foucault (4) | Second | 6 out |
| Wednesday, June 9 |
| » Lost to Rangers (30-20), 4-1 | Memorial Stadium (12-17) | 24-27 | Lost 5 |
| » W: Gaylord Perry (6-4) L: Ken Holtzman (5-4) | Third | 7 out |
| Thursday, June 10 |
| » Lost to Royals (33-19), 7-0 | Royals Stadium (0-1) | 24-28 | Lost 6 |
| » W: Paul Splittorff (5-6) L: Jim Palmer (6-7) | Third | 7 out |
| Friday, June 11 |
| » Lost to Royals (34-19), 4-0 | Royals Stadium (0-2) | 24-29 | Lost 7 |
| » W: Doug Bird (7-1) L: Mike Cuellar (2-7) S: Mark Littell (6) | Fourth | 8 out |
| Saturday, June 12 |
| » Lost to Royals (35-19), 7-6 | Royals Stadium (0-3) | 24-30 | Lost 8 |
| » W: Steve Busby (3-1) L: Doyle Alexander (3-4) S: Marty Pattin (5) | Fifth | 8 out |
| Sunday, June 13 |
| » Lost to Royals (36-19), 8-4 | Royals Stadium (0-4) | 24-31 | Lost 9 |
| » W: Dennis Leonard (6-2) L: Mike Flanagan (0-2) | Fifth | 8 out |
| Tuesday, June 15 |
| » Defeated White Sox (27-27), 4-0 | Comiskey Park I (1-0) | 25-31 | |
| » W: Jim Palmer (7-7) L: Rich Gossage (5-4) | Fourth | 8 out |
| Wednesday, June 16 |
| » Defeated White Sox (27-28), 10-2 | Comiskey Park I (2-0) | 26-31 | Won 2 |
| » W: Mike Cuellar (3-7) L: Francisco Barrios (1-2) | Fourth | 8 out |
| » Major-league debuts: Kevin Bell (White Sox) |
| Thursday, June 17 |
| » Defeated Rangers (33-23), 4-1 | Arlington Stadium (1-0) | 27-31 | Won 3 |
| » W: Wayne Garland (6-0) L: Nelson Briles (6-3) S: Dave Pagan (1) | Fourth | 8 out |
| Friday, June 18 |
| » Defeated Rangers (33-24), 9-4 | Arlington Stadium (2-0) | 28-31 | Won 4 |
| » W: Rudy May (5-3) L: Jim Umbarger (7-5) | Third | 8 out |
| Saturday, June 19 |
| » Defeated Rangers (33-25), 8-4 | Arlington Stadium (3-0) | 29-31 | Won 5 |
| » W: Jim Palmer (8-7) L: Steve Foucault (5-3) | Fourth | 8 out |
| Sunday, June 20 |
| » Defeated Rangers (33-26), 2-0 | Arlington Stadium (4-0) | 30-31 | Won 6 |
| » W: Mike Cuellar (4-7) L: Gaylord Perry (7-5) | Fourth | 8 out |
| Monday, June 21 |
| » Defeated Red Sox (29-31), 2-0 | Memorial Stadium (13-17) | 31-31 | Won 7 |
| » W: Wayne Garland (7-0) L: Luis Tiant (8-5) | Third | 8 out |
| Tuesday, June 22 |
| » Lost to Red Sox (30-31), 6-5 | Memorial Stadium (13-18) | 31-32 | |
| » W: Reggie Cleveland (4-2) L: Dave Pagan (1-2) | Fourth | 8 out |
| Wednesday, June 23 |
| » Defeated Red Sox (30-32), 3-2 | Memorial Stadium (14-18) | 32-32 | |
| » W: Jim Palmer (9-7) L: Jim Willoughby (1-4) | Third | 7 out |
| Friday, June 25 |
| » Lost to Indians (33-31), 6-5 | Memorial Stadium (14-19) | 32-33 | |
| » W: Stan Thomas (1-1) L: Dave Pagan (1-3) | Third | 8½ out |
| Saturday, June 26 |
| » Defeated Indians (33-32), 2-1 | Memorial Stadium (15-19) | 33-33 | |
| » W: Wayne Garland (8-0) L: Dennis Eckersley (3-7) | Third | 8½ out |
| Sunday, June 27 |
| » Lost to Indians (34-32), 6-3 | Memorial Stadium (15-20) | 33-34 | |
| » W: Pat Dobson (9-5) L: Rudy May (5-4) S: Jim Kern (4) | Third | 9½ out |
| » Defeated Indians (34-33), 6-2 | Memorial Stadium (16-20) | 34-34 | |
| » W: Ross Grimsley (2-4) L: Rick Waits (2-2) S: Tippy Martinez (3) | Third | 9½ out |
| Monday, June 28 |
| » Lost to Red Sox (32-35), 12-8 | Fenway Park (2-2) | 34-35 | |
| » W: Fergie Jenkins (6-8) L: Mike Flanagan (0-3) | Third | 9½ out |
| Tuesday, June 29 |
| » Lost to Red Sox (33-35), 2-0 | Fenway Park (2-3) | 34-36 | Lost 2 |
| » W: Rick Wise (6-5) L: Mike Cuellar (4-8) | Fourth | 9½ out |
| Wednesday, June 30 |
| » Lost to Red Sox (34-35), 6-4 | Fenway Park (2-4) | 34-37 | Lost 3 |
| » W: Jim Willoughby (2-4) L: Wayne Garland (8-1) | Fourth | 10 out |
| Thursday, July 1 |
| » Lost to Tigers (35-35), 2-0 | Memorial Stadium (16-21) | 34-38 | Lost 4 |
| » W: Dave Roberts (8-6) L: Rudy May (5-5) | Fifth | 10 out |
| Friday, July 2 |
| » Defeated Tigers (35-36), 2-1 | Memorial Stadium (17-21) | 35-38 | |
| » W: Jim Palmer (10-7) L: Vern Ruhle (5-4) | Fourth | 10 out |
| Saturday, July 3 |
| » Lost to Tigers (36-36), 4-0 | Tiger Stadium (2-2) | 35-39 | |
| » W: Mark Fidrych (9-1) L: Mike Cuellar (4-9) | Fifth | 11 out |
| Sunday, July 4 |
| » Defeated Tigers (36-37), 7-4 | Tiger Stadium (3-2) | 36-39 | |
| » W: Wayne Garland (9-1) L: John Hiller (6-4) | Fourth | 11 out |
| Monday, July 5 |
| » Lost to Athletics (39-40), 4-1 | Oakland-Alameda County Stadium (1-2) | 36-40 | |
| » W: Mike Torrez (7-9) L: Rudy May (5-6) S: Rollie Fingers (11) | Fourth | 11 out |
| Future Oriole Jay Spurgeon is born in West Covina, CA. |
| Tuesday, July 6 |
| » Lost to Athletics (40-40), 2-0 | Oakland-Alameda County Stadium (1-3) | 36-41 | Lost 2 |
| » W: Vida Blue (7-7) L: Jim Palmer (10-8) | Fourth | 11½ out |
| Wednesday, July 7 |
| » Lost to Athletics (41-40), 5-3 | Oakland-Alameda County Stadium (1-4) | 36-42 | Lost 3 |
| » W: Paul Mitchell (4-5) L: Mike Cuellar (4-10) S: Rollie Fingers (12) | Fourth | 11½ out |
| Thursday, July 8 |
| » Defeated Athletics (41-41), 9-6 | Oakland-Alameda County Stadium (2-4) | 37-42 | |
| » W: Wayne Garland (10-1) L: Paul Lindblad (4-2) S: Dyar Miller (4) | Fifth | 11½ out |
| Friday, July 9 |
| » Defeated Angels (35-50), 4-3 | Anaheim Stadium (2-2) | 38-42 | Won 2 |
| » W: Rudy May (6-6) L: Frank Tanana (10-6) S: Tippy Martinez (4) | Fifth | 11½ out |
| Saturday, July 10 |
| » Defeated Angels (35-51), 5-2 | Anaheim Stadium (3-2) | 39-42 | Won 3 |
| » W: Jim Palmer (11-8) L: Gary Ross (6-10) | Fourth | 10½ out |
| Sunday, July 11 |
| » Defeated Angels (35-52), 3-1 | Anaheim Stadium (4-2) | 40-42 | Won 4 |
| » W: Dave Pagan (2-3) L: Nolan Ryan (7-10) S: Tippy Martinez (5) | Third | 10½ out |
| Thursday, July 15 |
| » Defeated Angels (35-53), 4-0 | Memorial Stadium (18-21) | 41-42 | Won 5 |
| » W: Jim Palmer (12-8) L: Gary Ross (6-11) | Third | 11 out |
| Friday, July 16 |
| » Defeated Angels (35-54), 5-4 | Memorial Stadium (19-21) | 42-42 | Won 6 |
| » W: Wayne Garland (11-1) L: Nolan Ryan (7-11) S: Dyar Miller (5) | Second | 11 out |
| Saturday, July 17 |
| » Lost to Angels (36-54), 7-3 | Memorial Stadium (19-22) | 42-43 | |
| » W: Frank Tanana (11-6) L: Rudy May (6-7) | Second | 12 out |
| Sunday, July 18 |
| » Lost to Angels (37-54), 8-6 | Memorial Stadium (19-23) | 42-44 | Lost 2 |
| » W: Dick Drago (3-7) L: Mike Cuellar (4-11) | Third | 12 out |
| Monday, July 19 |
| » Defeated Royals (56-33), 4-3 | Royals Stadium (1-4) | 43-44 | |
| » W: Jim Palmer (13-8) L: Dennis Leonard (10-4) S: Tippy Martinez (6) | Third | 12 out |
| Tuesday, July 20 |
| » Defeated Royals (56-34), 10-3 | Royals Stadium (2-4) | 44-44 | Won 2 |
| » W: Wayne Garland (12-1) L: Doug Bird (9-3) | Second | 12 out |
| Wednesday, July 21 |
| » Defeated Rangers (46-44), 6-4 | Arlington Stadium (5-0) | 45-44 | Won 3 |
| » W: Tippy Martinez (3-0) L: Joe Hoerner (0-3) S: Fred Holdsworth (1) | Second | 12 out |
| Thursday, July 22 |
| » Defeated Rangers (46-45), 4-3 | Arlington Stadium (6-0) | 46-44 | Won 4 |
| » W: Fred Holdsworth (1-0) L: Gaylord Perry (9-8) | Second | 11 out |
| Friday, July 23 |
| » Lost to Brewers (38-50), 4-3 | Memorial Stadium (19-24) | 46-45 | |
| » W: Jim Slaton (11-8) L: Tippy Martinez (3-1) S: Danny Frisella (7) | Third | 12 out |
| Saturday, July 24 |
| » Lost to Brewers (39-50), 4-1 | Memorial Stadium (19-25) | 46-46 | Lost 2 |
| » W: Eduardo Rodriguez (3-6) L: Mike Cuellar (4-12) S: Bill Castro (2) | Third | 13½ out |
| » Lost to Brewers (40-50), 5-0 | Memorial Stadium (19-26) | 46-47 | Lost 3 |
| » W: Jerry Augustine (4-7) L: Wayne Garland (12-2) | Third | 13½ out |
| Sunday, July 25 |
| » Lost to Brewers (41-50), 3-1 | Memorial Stadium (19-27) | 46-48 | Lost 4 |
| » W: Bill Travers (12-7) L: Dave Pagan (2-4) | Third | 14½ out |
| Monday, July 26 |
| » Defeated Yankees (60-34), 3-1 | Memorial Stadium (20-27) | 47-48 | |
| » W: Ross Grimsley (3-4) L: Catfish Hunter (12-9) | Third | 13½ out |
| Tuesday, July 27 |
| » Defeated Yankees (60-35), 4-1 | Memorial Stadium (21-27) | 48-48 | Won 2 |
| » W: Jim Palmer (14-8) L: Dock Ellis (11-5) | Second | 12½ out |
| Wednesday, July 28 |
| » Defeated Yankees (60-36), 4-3 | Memorial Stadium (22-27) | 49-48 | Won 3 |
| » W: Tippy Martinez (4-1) L: Doyle Alexander (5-7) | Second | 11½ out |
| Thursday, July 29 |
| » Defeated Tigers (47-50), 1-0 | Tiger Stadium (4-2) | 50-48 | Won 4 |
| » W: Rudy May (7-7) L: Mark Fidrych (11-3) | Second | 11 out |
| Friday, July 30 |
| » Defeated Tigers (47-51), 7-3 | Tiger Stadium (5-2) | 51-48 | Won 5 |
| » W: Ross Grimsley (4-4) L: Vern Ruhle (6-8) | Second | 11 out |
| Saturday, July 31 |
| » Lost to Tigers (48-51), 5-4 | Memorial Stadium (22-28) | 51-49 | |
| » W: Dave Lemanczyk (3-2) L: Jim Palmer (14-9) S: John Hiller (10) | Second | 10½ out |
| Sunday, August 1 |
| » Defeated Tigers (48-52), 4-3 | Memorial Stadium (23-28) | 52-49 | |
| » W: Fred Holdsworth (2-0) L: John Hiller (10-5) | Second | 9½ out |
| Monday, August 2 |
| » Lost to Brewers (44-55), 7-1 | County Stadium (3-1) | 52-50 | |
| » W: Jim Colborn (7-11) L: Rudy May (7-8) | Second | 10½ out |
| Tuesday, August 3 |
| » Lost to Brewers (45-55), 4-2 | County Stadium (3-2) | 52-51 | Lost 2 |
| » W: Eduardo Rodriguez (4-7) L: Ross Grimsley (4-5) | Second | 11½ out |
| Wednesday, August 4 |
| » Lost to Indians (52-51), 3-0 | Cleveland Stadium (1-3) | 52-52 | Lost 3 |
| » W: Rick Waits (5-5) L: Jim Palmer (14-10) | Third | 12 out |
| Thursday, August 5 |
| » Defeated Indians (52-52), 6-2 | Cleveland Stadium (2-3) | 53-52 | |
| » W: Wayne Garland (13-2) L: Jim Bibby (7-4) | Second | 11 out |
| Saturday, August 7 |
| » Defeated Yankees (64-42), 7-4 | Yankee Stadium (3-1) | 54-52 | Won 2 |
| » W: Rudy May (8-8) L: Doyle Alexander (6-8) | Second | 10 out |
| Sunday, August 8 |
| » Defeated Yankees (64-43), 8-5 | Yankee Stadium (4-1) | 55-52 | Won 3 |
| » W: Ross Grimsley (5-5) L: Catfish Hunter (12-12) S: Mike Cuellar (1) | Second | 9 out |
| Monday, August 9 |
| » Major-league debuts: Garry Templeton (Cardinals) |
| Tuesday, August 10 |
| » Defeated Twins (55-56), 2-0 | Memorial Stadium (24-28) | 56-52 | Won 4 |
| » W: Jim Palmer (15-10) L: Dave Goltz (9-11) | Second | 8½ out |
| Wednesday, August 11 |
| » Lost to Twins (56-56), 2-0 | Memorial Stadium (24-29) | 56-53 | |
| » W: Bill Singer (9-8) L: Wayne Garland (13-3) | Second | 9½ out |
| Friday, August 13 |
| » Lost to White Sox (49-63), 5-2 | Memorial Stadium (24-30) | 56-54 | Lost 2 |
| » W: Rich Gossage (7-11) L: Rudy May (8-9) S: Dave Hamilton (7) | Second | 11 out |
| Saturday, August 14 |
| » Defeated White Sox (49-64), 8-6 | Memorial Stadium (25-30) | 57-54 | |
| » W: Jim Palmer (16-10) L: Terry Forster (2-9) S: Fred Holdsworth (2) | Second | 10½ out |
| » Defeated White Sox (49-65), 6-5 | Memorial Stadium (26-30) | 58-54 | Won 2 |
| » W: Dyar Miller (2-2) L: Ken Brett (6-8) S: Tippy Martinez (7) | Second | 10½ out |
| Sunday, August 15 |
| » Defeated White Sox (49-66), 3-0 | Memorial Stadium (27-30) | 59-54 | Won 3 |
| » W: Wayne Garland (14-3) L: Francisco Barrios (3-6) | Second | 9½ out |
| Monday, August 16 |
| » Defeated Twins (57-60), 8-4 | Metropolitan Stadium (1-2) | 60-54 | Won 4 |
| » W: Ross Grimsley (6-5) L: Steve Luebber (3-4) | Second | 9½ out |
| Tuesday, August 17 |
| » Defeated Twins (57-61), 10-3 | Metropolitan Stadium (2-2) | 61-54 | Won 5 |
| » W: Rudy May (9-9) L: Tom Johnson (1-1) | Second | 9½ out |
| Wednesday, August 18 |
| » Lost to Twins (58-61), 5-1 | Metropolitan Stadium (2-3) | 61-55 | |
| » W: Dave Goltz (10-12) L: Jim Palmer (16-11) S: Bill Campbell (14) | Second | 10½ out |
| Thursday, August 19 |
| » Lost to Twins (59-61), 5-4 | Metropolitan Stadium (2-4) | 61-56 | Lost 2 |
| » W: Bill Singer (10-8) L: Dave Pagan (2-5) S: Bill Campbell (15) | Second | 11 out |
| Friday, August 20 |
| » Defeated White Sox (52-69), 6-4 | Comiskey Park I (3-0) | 62-56 | |
| » W: Wayne Garland (15-3) L: Francisco Barrios (3-7) | Second | 10 out |
| Future Oriole Eugene Kingsale is born in Solito, Aruba. |
| Saturday, August 21 |
| » Lost to White Sox (53-69), 11-10 | Comiskey Park I (3-1) | 62-57 | |
| » W: Dave Hamilton (5-5) L: Mike Cuellar (4-13) | Second | 10 out |
| Sunday, August 22 |
| » Defeated White Sox (53-70), 6-2 | Comiskey Park I (4-1) | 63-57 | |
| » W: Jim Palmer (17-11) L: Ken Kravec (0-1) | Second | 9½ out |
| » Lost to White Sox (54-70), 7-3 | Comiskey Park I (4-2) | 63-58 | |
| » W: Pete Vuckovich (7-3) L: Ross Grimsley (6-6) S: Francisco Barrios (3) | Second | 9½ out |
| Monday, August 23 |
| » Lost to Athletics (67-57), 3-0 | Memorial Stadium (27-31) | 63-59 | Lost 2 |
| » W: Vida Blue (12-11) L: Mike Flanagan (0-4) | Second | 10½ out |
| Tuesday, August 24 |
| » Lost to Athletics (68-57), 5-4 | Memorial Stadium (27-32) | 63-60 | Lost 3 |
| » W: Stan Bahnsen (7-3) L: Wayne Garland (15-4) S: Paul Lindblad (4) | Second | 11½ out |
| Wednesday, August 25 |
| » Defeated Athletics (68-58), 9-4 | Memorial Stadium (28-32) | 64-60 | |
| » W: Rudy May (10-9) L: Paul Mitchell (8-6) | Second | 11½ out |
| Friday, August 27 |
| » Defeated Rangers (58-69), 3-0 | Memorial Stadium (29-32) | 65-60 | Won 2 |
| » W: Jim Palmer (18-11) L: Gaylord Perry (12-11) | Second | 11½ out |
| Saturday, August 28 |
| » Defeated Rangers (58-70), 6-4 | Memorial Stadium (30-32) | 66-60 | Won 3 |
| » W: Fred Holdsworth (3-0) L: Steve Hargan (5-6) | Second | 11½ out |
| Sunday, August 29 |
| » Lost to Rangers (59-70), 11-0 | Memorial Stadium (30-33) | 66-61 | |
| » W: Jim Umbarger (9-10) L: Wayne Garland (15-5) | Second | 11½ out |
| Monday, August 30 |
| » Defeated Royals (78-52), 3-2 | Memorial Stadium (31-33) | 67-61 | |
| » W: Rudy May (11-9) L: Andy Hassler (4-8) | Second | 11½ out |
| Tuesday, August 31 |
| » Defeated Royals (78-53), 4-3 | Memorial Stadium (32-33) | 68-61 | Won 2 |
| » W: Jim Palmer (19-11) L: Marty Pattin (6-11) S: Dyar Miller (6) | Second | 11½ out |
| Wednesday, September 1 |
| » Defeated Royals (78-54), 7-1 | Memorial Stadium (33-33) | 69-61 | Won 3 |
| » W: Mike Flanagan (1-4) L: Doug Bird (11-7) | Second | 10½ out |
| Friday, September 3 |
| » Lost to Yankees (80-50), 3-1 | Memorial Stadium (33-34) | 69-62 | |
| » W: Dock Ellis (14-6) L: Wayne Garland (15-6) S: Dick Tidrow (5) | Second | 11½ out |
| Saturday, September 4 |
| » Lost to Yankees (81-50), 4-2 | Memorial Stadium (33-35) | 69-63 | Lost 2 |
| » W: Ken Holtzman (12-8) L: Jim Palmer (19-12) S: Dick Tidrow (6) | Second | 11½ out |
| » Defeated Yankees (81-51), 6-2 | Memorial Stadium (34-35) | 70-63 | |
| » W: Rudy May (12-9) L: Ed Figueroa (16-8) | Second | 11½ out |
| Sunday, September 5 |
| » Defeated Yankees (81-52), 5-3 | Memorial Stadium (35-35) | 71-63 | Won 2 |
| » W: Ross Grimsley (7-6) L: Catfish Hunter (14-14) S: Tippy Martinez (8) | Second | 10½ out |
| Monday, September 6 |
| » Lost to Tigers (63-72), 5-4 | Tiger Stadium (5-3) | 71-64 | |
| » W: Dave Roberts (13-14) L: Dyar Miller (2-3) | Second | 11½ out |
| Tuesday, September 7 |
| » Defeated Tigers (63-73), 5-3 | Tiger Stadium (6-3) | 72-64 | |
| » W: Wayne Garland (16-6) L: Mark Fidrych (15-8) | Second | 11½ out |
| Wednesday, September 8 |
| » Defeated Indians (70-68), 3-1 | Memorial Stadium (36-35) | 73-64 | Won 2 |
| » W: Jim Palmer (20-12) L: Dennis Eckersley (10-12) | Second | 11½ out |
| Thursday, September 9 |
| » Lost to Indians (71-68), 4-3 | Memorial Stadium (36-36) | 73-65 | |
| » W: Pat Dobson (14-11) L: Rudy May (12-10) S: Dave LaRoche (17) | Second | 12½ out |
| Friday, September 10 |
| » Defeated Indians (71-69), 4-3 | Memorial Stadium (37-36) | 74-65 | |
| » W: Ross Grimsley (8-6) L: Rick Waits (7-6) S: Dyar Miller (7) | Second | 12½ out |
| Saturday, September 11 |
| » Defeated Brewers (62-77), 5-1 | County Stadium (4-2) | 75-65 | Won 2 |
| » W: Wayne Garland (17-6) L: Eduardo Rodriguez (5-12) | Second | 11 out |
| » Defeated Brewers (62-78), 3-2 | County Stadium (5-2) | 76-65 | Won 3 |
| » W: Mike Flanagan (2-4) L: Jim Colborn (8-14) | Second | 11 out |
| » Major-league debuts: Rich Dauer and Kiko Garcia (Orioles) |
| Sunday, September 12 |
| » Defeated Brewers (62-79), 3-1 | County Stadium (6-2) | 77-65 | Won 4 |
| » W: Jim Palmer (21-12) L: Jerry Augustine (8-11) | Second | 10½ out |
| Monday, September 13 |
| » Defeated Brewers (62-80), 5-3 | County Stadium (7-2) | 78-65 | Won 5 |
| » W: Fred Holdsworth (4-0) L: Bill Castro (4-5) | Second | 9½ out |
| Tuesday, September 14 |
| » Defeated Tigers (67-77), 9-7 | Memorial Stadium (38-36) | 79-65 | Won 6 |
| » W: Dennis Martinez (1-0) L: John Hiller (11-8) | Second | 9½ out |
| » Major-league debuts: Dennis Martinez (Orioles) |
| Wednesday, September 15 |
| » Defeated Tigers (67-78), 1-0 | Memorial Stadium (39-36) | 80-65 | Won 7 |
| » W: Wayne Garland (18-6) L: Dave Roberts (14-15) | Second | 9½ out |
| Saturday, September 18 |
| » Lost to Indians (74-72), 5-1 | Cleveland Stadium (2-4) | 80-66 | |
| » W: Stan Thomas (4-3) L: Jim Palmer (21-13) S: Jim Kern (14) | Second | 10½ out |
| » Defeated Indians (74-73), 3-2 | Cleveland Stadium (3-4) | 81-66 | |
| » W: Rudy May (13-10) L: Jim Bibby (12-6) S: Tippy Martinez (9) | Second | 10½ out |
| Sunday, September 19 |
| » Lost to Indians (75-73), 5-4 | Cleveland Stadium (3-5) | 81-67 | |
| » W: Pat Dobson (15-12) L: Wayne Garland (18-7) S: Dave LaRoche (20) | Second | 12 out |
| » Lost to Indians (76-73), 3-2 | Cleveland Stadium (3-6) | 81-68 | Lost 2 |
| » W: Jim Kern (10-7) L: Dyar Miller (2-4) | Second | 12 out |
| » Major-league debuts: Scott McGregor (Orioles) |
| Tuesday, September 21 |
| » Defeated Yankees (92-57), 11-8 | Yankee Stadium (5-1) | 82-68 | |
| » W: Tippy Martinez (5-1) L: Dick Tidrow (4-5) | Second | 10½ out |
| Wednesday, September 22 |
| » Defeated Yankees (92-58), 2-0 | Yankee Stadium (6-1) | 83-68 | Won 2 |
| » W: Jim Palmer (22-13) L: Dock Ellis (16-8) | Second | 8½ out |
| » Defeated Yankees (92-59), 5-2 | Yankee Stadium (7-1) | 84-68 | Won 3 |
| » W: Rudy May (14-10) L: Ed Figueroa (19-9) S: Tippy Martinez (10) | Second | 8½ out |
| Thursday, September 23 |
| » Defeated Yankees (92-60), 2-1 | Yankee Stadium (8-1) | 85-68 | Won 4 |
| » W: Mike Flanagan (3-4) L: Catfish Hunter (16-15) | Second | 7½ out |
| Frida |