| Sunday, February 1 |
| Future Cub Phil Norton is born in Texarkana, TX. |
| Wednesday, March 17 |
| Future Cub Scott Downs is born in Louisville, KY. |
| Monday, April 5 |
| Future Cub Ross Gload is born in Brooklyn, NY. |
| Friday, April 9 |
| » Lost to Cardinals (1-0), 5-0 | Busch Stadium II (0-1) | 0-1 | |
| » W: Lynn McGlothen (1-0) L: Ray Burris (0-1) | Third | 1 out |
| Saturday, April 10 |
| » Defeated Cardinals (1-1), 4-3 | Busch Stadium II (1-1) | 1-1 | |
| » W: Bill Bonham (1-0) L: Eric Rasmussen (0-1) S: Darold Knowles (1) | Third | 1 out |
| » Major-league debuts: Mike Proly (Cardinals) |
| Sunday, April 11 |
| » Defeated Cardinals (1-2), 8-5 | Busch Stadium II (2-1) | 2-1 | Won 2 |
| » W: Darold Knowles (1-0) L: Jack Curtis (0-1) | Second | ½ out |
| Tuesday, April 13 |
| » Defeated Mets (2-2), 5-4 | Wrigley Field (1-0) | 3-1 | Won 3 |
| » W: Mike Garman (1-0) L: Skip Lockwood (0-1) | Second | ½ out |
| Wednesday, April 14 |
| » Defeated Mets (2-3), 6-5 | Wrigley Field (2-0) | 4-1 | Won 4 |
| » W: Buddy Schultz (1-0) L: Hank Webb (0-1) S: Mike Garman (1) | Second | 1 out |
| Future Cub Kyle Farnsworth is born in Wichita, KS. |
| Thursday, April 15 |
| » Lost to Mets (3-3), 10-8 | Wrigley Field (2-1) | 4-2 | |
| » W: Skip Lockwood (1-1) L: Tom Dettore (0-1) | Second | 1 out |
| Saturday, April 17 |
| » Lost to Phillies (2-3), 18-16 | Wrigley Field (2-2) | 4-3 | Lost 2 |
| » W: Tug McGraw (1-1) L: Darold Knowles (1-1) S: Jim Lonborg (1) | Second | 1½ out |
| Sunday, April 18 |
| » Lost to Phillies (3-3), 8-5 | Wrigley Field (2-3) | 4-4 | Lost 3 |
| » W: Larry Christenson (1-0) L: Ray Burris (0-2) S: Gene Garber (1) | Third | 2½ out |
| Monday, April 19 |
| » Lost to Expos (3-5), 4-3 | Wrigley Field (2-4) | 4-5 | Lost 4 |
| » W: Steve Rogers (1-2) L: Bill Bonham (1-1) S: Wayne Granger (2) | Fourth | 3 out |
| Wednesday, April 21 |
| » Lost to Expos (4-5), 12-6 | Wrigley Field (2-5) | 4-6 | Lost 5 |
| » W: Woodie Fryman (2-1) L: Geoff Zahn (0-1) | Fifth | 2½ out |
| Thursday, April 22 |
| » Defeated Expos (4-6), 5-4 | Wrigley Field (3-5) | 5-6 | |
| » W: Oscar Zamora (1-0) L: Dale Murray (0-1) | Fourth | 2 out |
| Friday, April 23 |
| » Defeated Dodgers (3-9), 4-3 | Dodger Stadium (1-0) | 6-6 | Won 2 |
| » W: Paul Reuschel (1-0) L: Al Downing (0-1) | Third | 1 out |
| Saturday, April 24 |
| » Lost to Dodgers (4-9), 2-1 | Dodger Stadium (1-1) | 6-7 | |
| » W: Don Sutton (1-3) L: Bill Bonham (1-2) | Fourth | 1½ out |
| Sunday, April 25 |
| » Lost to Dodgers (5-9), 5-4 | Dodger Stadium (1-2) | 6-8 | Lost 2 |
| » W: Charlie Hough (1-0) L: Mike Garman (1-1) | Fourth | 2 out |
| Monday, April 26 |
| » Lost to Padres (8-7), 6-2 | San Diego/Jack Murphy Stadium (0-1) | 6-9 | Lost 3 |
| » W: Bill Greif (1-1) L: Rick Reuschel (0-1) S: Butch Metzger (1) | Fifth | 2½ out |
| Tuesday, April 27 |
| » Defeated Padres (8-8), 4-2 | San Diego/Jack Murphy Stadium (1-1) | 7-9 | |
| » W: Ray Burris (1-2) L: Dave Wehrmeister (0-3) S: Buddy Schultz (1) | Fifth | 2½ out |
| Wednesday, April 28 |
| » Defeated Padres (8-9), 8-5 | San Diego/Jack Murphy Stadium (2-1) | 8-9 | Won 2 |
| » W: Bill Bonham (2-2) L: Randy Jones (4-1) S: Buddy Schultz (2) | Fourth | 2½ out |
| Thursday, April 29 |
| » Lost to Padres (9-9), 9-5 | San Diego/Jack Murphy Stadium (2-2) | 8-10 | |
| » W: Butch Metzger (3-0) L: Mike Garman (1-2) | Fifth | 3½ out |
| Friday, April 30 |
| » Defeated Giants (7-10), 5-2 | Candlestick Park (1-0) | 9-10 | |
| » W: Rick Reuschel (1-1) L: Ed Halicki (2-3) | Fourth | 3½ out |
| Saturday, May 1 |
| » Lost to Giants (8-10), 3-1 | Candlestick Park (1-1) | 9-11 | |
| » W: Gary Lavelle (1-0) L: Buddy Schultz (1-1) | Fourth | 4 out |
| Sunday, May 2 |
| » Defeated Giants (8-11), 6-5 | Candlestick Park (2-1) | 10-11 | |
| » W: Ken Frailing (1-0) L: Gary Lavelle (1-1) | Fourth | 2½ out |
| » Defeated Giants (8-12), 6-5 | Candlestick Park (3-1) | 11-11 | Won 2 |
| » W: Darold Knowles (2-1) L: Greg Minton (0-2) S: Rick Reuschel (1) | Fourth | 2½ out |
| Tuesday, May 4 |
| » Lost to Dodgers (13-9), 9-6 | Wrigley Field (3-6) | 11-12 | |
| » W: Burt Hooton (2-2) L: Rick Reuschel (1-2) S: Mike Marshall (4) | Fourth | 3½ out |
| Wednesday, May 5 |
| » Lost to Dodgers (14-9), 14-12 | Wrigley Field (3-7) | 11-13 | Lost 2 |
| » W: Don Sutton (3-3) L: Ray Burris (1-3) S: Mike Marshall (5) | Fourth | 4½ out |
| Friday, May 7 |
| » Lost to Reds (13-10), 3-1 | Wrigley Field (3-8) | 11-14 | Lost 3 |
| » W: Jack Billingham (3-2) L: Ken Frailing (1-1) S: Rawly Eastwick (3) | Fifth | 5½ out |
| Saturday, May 8 |
| » Lost to Reds (14-10), 14-4 | Wrigley Field (3-9) | 11-15 | Lost 4 |
| » W: Santo Alcala (1-0) L: Rick Reuschel (1-3) | Fifth | 6½ out |
| Sunday, May 9 |
| » Lost to Reds (15-10), 14-2 | Wrigley Field (3-10) | 11-16 | Lost 5 |
| » W: Pat Zachry (1-0) L: Ray Burris (1-4) | Fifth | 6½ out |
| » Major-league debuts: Bruce Sutter (Cubs) |
| Tuesday, May 11 |
| » Defeated Giants (9-18), 4-0 | Wrigley Field (4-10) | 12-16 | |
| » W: Oscar Zamora (2-0) L: Ed Halicki (2-5) | Fourth | 6½ out |
| Wednesday, May 12 |
| » Defeated Giants (9-19), 1-0 | Wrigley Field (5-10) | 13-16 | Won 2 |
| » W: Mike Garman (2-2) L: Randy Moffitt (1-1) | Fourth | 5½ out |
| Thursday, May 13 |
| » Lost to Giants (10-19), 9-5 | Wrigley Field (5-11) | 13-17 | |
| » W: Randy Moffitt (2-1) L: Bruce Sutter (0-1) | Fourth | 6 out |
| Friday, May 14 |
| » Lost to Padres (15-14), 7-4 | Wrigley Field (5-12) | 13-18 | Lost 2 |
| » W: Brent Strom (4-1) L: Paul Reuschel (1-1) S: Butch Metzger (4) | Fifth | 7 out |
| Sunday, May 16 |
| » Defeated Padres (15-15), 6-5 | Wrigley Field (6-12) | 14-18 | |
| » W: Rick Reuschel (2-3) L: Bill Greif (1-3) S: Darold Knowles (2) | Fourth | 7½ out |
| Thursday, May 20 |
| » Lost to Expos (13-17), 3-0 | Parc Jarry (0-1) | 14-19 | |
| » W: Woodie Fryman (5-2) L: Ray Burris (1-5) S: Dale Murray (3) | Fifth | 9 out |
| Friday, May 21 |
| » Defeated Pirates (20-14), 5-4 | Three Rivers Stadium (1-0) | 15-19 | |
| » W: Rick Reuschel (3-3) L: Larry Demery (1-1) S: Darold Knowles (3) | Fourth | 9 out |
| Saturday, May 22 |
| » Lost to Pirates (21-14), 4-3 | Three Rivers Stadium (1-1) | 15-20 | |
| » W: Bob Moose (1-0) L: Paul Reuschel (1-2) | Fourth | 9 out |
| Sunday, May 23 |
| » Defeated Pirates (21-15), 6-5 | Three Rivers Stadium (2-1) | 16-20 | |
| » W: Oscar Zamora (3-0) L: Kent Tekulve (0-1) S: Bruce Sutter (1) | Fourth | 9½ out |
| » Lost to Pirates (22-15), 9-1 | Three Rivers Stadium (2-2) | 16-21 | |
| » W: Jerry Reuss (5-3) L: Mike Garman (2-3) | Fourth | 9½ out |
| Tuesday, May 25 |
| » Lost to Cardinals (17-23), 5-2 | Wrigley Field (6-13) | 16-22 | Lost 2 |
| » W: Lynn McGlothen (5-3) L: Ray Burris (1-6) | Sixth | 11 out |
| Wednesday, May 26 |
| » Defeated Cardinals (17-24), 4-2 | Wrigley Field (7-13) | 17-22 | |
| » W: Rick Reuschel (4-3) L: John Denny (2-3) S: Darold Knowles (4) | Fifth | 11 out |
| Thursday, May 27 |
| » Defeated Cardinals (17-25), 2-1 | Wrigley Field (8-13) | 18-22 | Won 2 |
| » W: Steve Renko (1-1) L: Pete Falcone (2-4) S: Darold Knowles (5) | Fourth | 10 out |
| Friday, May 28 |
| » Major-league debuts: Bob Myrick (Mets) |
| Saturday, May 29 |
| » Defeated Pirates (23-18), 4-1 | Wrigley Field (9-13) | 19-22 | Won 3 |
| » W: Bill Bonham (3-2) L: Bruce Kison (3-4) S: Oscar Zamora (1) | Fourth | 10½ out |
| Sunday, May 30 |
| » Lost to Pirates (24-18), 4-2 | Wrigley Field (9-14) | 19-23 | |
| » W: Jim Rooker (6-1) L: Ray Burris (1-7) | Fourth | 11½ out |
| Monday, May 31 |
| » Defeated Phillies (29-11), 7-5 | Veteran's Stadium (1-0) | 20-23 | |
| » W: Rick Reuschel (5-3) L: Steve Carlton (5-2) S: Bruce Sutter (2) | Fourth | 11½ out |
| » Lost to Phillies (30-11), 4-1 | Veteran's Stadium (1-1) | 20-24 | |
| » W: Jim Kaat (3-2) L: Mike Garman (2-4) | Fourth | 11½ out |
| Tuesday, June 1 |
| » Lost to Phillies (31-11), 6-1 | Veteran's Stadium (1-2) | 20-25 | Lost 2 |
| » W: Ron Reed (4-1) L: Steve Renko (1-2) | Fifth | 12½ out |
| Wednesday, June 2 |
| » Defeated Mets (24-26), 5-3 | Shea Stadium (1-0) | 21-25 | |
| » W: Bill Bonham (4-2) L: Craig Swan (2-5) | Fourth | 12½ out |
| Thursday, June 3 |
| » Defeated Mets (24-27), 2-1 | Shea Stadium (2-0) | 22-25 | Won 2 |
| » W: Ray Burris (2-7) L: Mickey Lolich (2-7) S: Oscar Zamora (2) | Fourth | 11½ out |
| Friday, June 4 |
| » Lost to Astros (24-28), 1-0 | Astrodome (0-1) | 22-26 | |
| » W: Mike Cosgrove (2-3) L: Rick Reuschel (5-4) | Fourth | 11½ out |
| Saturday, June 5 |
| » Lost to Astros (25-28), 4-3 | Astrodome (0-2) | 22-27 | Lost 2 |
| » W: J.R. Richard (6-5) L: Oscar Zamora (3-1) S: Ken Forsch (12) | Fourth | 11½ out |
| Sunday, June 6 |
| » Lost to Astros (26-28), 2-0 | Astrodome (0-3) | 22-28 | Lost 3 |
| » W: Joaquin Andujar (2-2) L: Bill Bonham (4-3) | Fourth | 13 out |
| » Lost to Astros (27-28), 5-1 | Astrodome (0-4) | 22-29 | Lost 4 |
| » W: Gil Rondon (2-1) L: Ken Frailing (1-2) S: Gene Pentz (2) | Fourth | 13 out |
| Tuesday, June 8 |
| » Lost to Braves (21-30), 7-3 | Wrigley Field (9-15) | 22-30 | Lost 5 |
| » W: Phil Niekro (4-4) L: Ray Burris (2-8) S: Adrian Devine (1) | Fifth | 14½ out |
| Wednesday, June 9 |
| » Lost to Braves (22-30), 2-0 | Wrigley Field (9-16) | 22-31 | Lost 6 |
| » W: Andy Messersmith (4-5) L: Joe Coleman (2-6) | Fifth | 14½ out |
| Thursday, June 10 |
| » Defeated Braves (22-31), 7-6 | Wrigley Field (10-16) | 23-31 | |
| » W: Steve Renko (2-2) L: Dick Ruthven (6-6) S: Oscar Zamora (3) | Fourth | 14½ out |
| Friday, June 11 |
| » Defeated Astros (29-30), 8-3 | Wrigley Field (11-16) | 24-31 | Won 2 |
| » W: Bill Bonham (5-3) L: Mike Cosgrove (2-4) S: Paul Reuschel (1) | Fourth | 14½ out |
| Saturday, June 12 |
| » Defeated Astros (29-31), 5-2 | Wrigley Field (12-16) | 25-31 | Won 3 |
| » W: Rick Reuschel (6-4) L: Joaquin Andujar (2-3) S: Darold Knowles (6) | Fourth | 14½ out |
| Sunday, June 13 |
| » Defeated Astros (29-32), 8-3 | Wrigley Field (13-16) | 26-31 | Won 4 |
| » W: Ray Burris (3-8) L: Larry Dierker (6-6) S: Paul Reuschel (2) | Fourth | 13 out |
| Monday, June 14 |
| » Lost to Reds (38-22), 3-2 | Riverfront Stadium (0-1) | 26-32 | |
| » W: Gary Nolan (6-3) L: Oscar Zamora (3-2) | Fourth | 13½ out |
| Tuesday, June 15 |
| » Lost to Reds (39-22), 6-4 | Riverfront Stadium (0-2) | 26-33 | Lost 2 |
| » W: Don Gullett (6-2) L: Darold Knowles (2-2) S: Rawly Eastwick (7) | Fourth | 14½ out |
| Wednesday, June 16 |
| » Defeated Reds (39-23), 5-3 | Riverfront Stadium (1-2) | 27-33 | |
| » W: Bill Bonham (6-3) L: Pat Zachry (5-2) | Fourth | 14½ out |
| Friday, June 18 |
| » Defeated Braves (24-36), 6-4 | Atlanta-Fulton County Stadium (1-0) | 28-33 | Won 2 |
| » W: Rick Reuschel (7-4) L: Carl Morton (0-6) S: Darold Knowles (7) | Fourth | 15 out |
| Saturday, June 19 |
| » Lost to Braves (25-36), 9-3 | Atlanta-Fulton County Stadium (1-1) | 28-34 | |
| » W: Andy Messersmith (6-5) L: Ray Burris (3-9) | Fourth | 15½ out |
| » Lost to Braves (26-36), 12-5 | Atlanta-Fulton County Stadium (1-2) | 28-35 | Lost 2 |
| » W: Phil Niekro (5-4) L: Joe Coleman (2-7) | Fourth | 15½ out |
| Sunday, June 20 |
| » Lost to Braves (27-36), 5-0 | Atlanta-Fulton County Stadium (1-3) | 28-36 | Lost 3 |
| » W: Dick Ruthven (8-6) L: Steve Renko (2-3) | Fourth | 16½ out |
| Tuesday, June 22 |
| » Lost to Pirates (36-26), 10-7 | Wrigley Field (13-17) | 28-37 | Lost 4 |
| » W: Larry Demery (4-1) L: Darold Knowles (2-3) S: Ramon Hernandez (3) | Fifth | 17 out |
| Wednesday, June 23 |
| » Defeated Pirates (36-27), 6-5 | Wrigley Field (14-17) | 29-37 | |
| » W: Oscar Zamora (4-2) L: Bob Moose (3-3) | Fifth | 17 out |
| Former Cub Lon Warneke dies in Hot Springs, AR at the age of 68. |
| Thursday, June 24 |
| » Defeated Pirates (36-28), 2-1 | Wrigley Field (15-17) | 30-37 | Won 2 |
| » W: Oscar Zamora (5-2) L: Rick Langford (0-1) | Fourth | 17 out |
| Friday, June 25 |
| » Lost to Mets (35-37), 7-4 | Wrigley Field (15-18) | 30-38 | |
| » W: Jon Matlack (9-2) L: Ray Burris (3-10) | Fourth | 18 out |
| Saturday, June 26 |
| » Lost to Mets (36-37), 10-2 | Wrigley Field (15-19) | 30-39 | Lost 2 |
| » W: Jerry Koosman (7-6) L: Bill Bonham (6-4) | Fifth | 18 out |
| Sunday, June 27 |
| » Lost to Mets (37-37), 13-3 | Wrigley Field (15-20) | 30-40 | Lost 3 |
| » W: Craig Swan (4-7) L: Rick Reuschel (7-5) | Fifth | 19 out |
| Monday, June 28 |
| » Lost to Pirates (39-29), 9-2 | Three Rivers Stadium (2-3) | 30-41 | Lost 4 |
| » W: Jim Rooker (7-3) L: Joe Coleman (2-8) | Fifth | 20 out |
| Tuesday, June 29 |
| » Lost to Pirates (40-29), 10-1 | Three Rivers Stadium (2-4) | 30-42 | Lost 5 |
| » W: John Candelaria (7-4) L: Steve Renko (2-4) | Fifth | 21 out |
| Wednesday, June 30 |
| » Lost to Pirates (41-29), 7-5 | Three Rivers Stadium (2-5) | 30-43 | Lost 6 |
| » W: Bruce Kison (6-4) L: Bill Bonham (6-5) S: Bob Moose (9) | Fifth | 21½ out |
| Friday, July 2 |
| » Lost to Mets (41-37), 2-1 | Shea Stadium (2-1) | 30-44 | Lost 7 |
| » W: Jerry Koosman (8-6) L: Joe Coleman (2-9) | Fifth | 21½ out |
| Saturday, July 3 |
| » Lost to Mets (42-37), 3-2 | Shea Stadium (2-2) | 30-45 | Lost 8 |
| » W: Skip Lockwood (5-2) L: Rick Reuschel (7-6) | Fifth | 22½ out |
| Sunday, July 4 |
| » Lost to Mets (43-37), 9-4 | Shea Stadium (2-3) | 30-46 | Lost 9 |
| » W: Craig Swan (5-7) L: Bill Bonham (6-6) S: Skip Lockwood (9) | Fifth | 22½ out |
| » Defeated Mets (43-38), 4-2 | Shea Stadium (3-3) | 31-46 | |
| » W: Ray Burris (4-10) L: Mickey Lolich (4-10) | Fifth | 22½ out |
| Monday, July 5 |
| » Defeated Padres (42-38), 1-0 | Wrigley Field (16-20) | 32-46 | Won 2 |
| » W: Steve Renko (3-4) L: Brent Strom (8-8) S: Joe Coleman (1) | Fifth | 21½ out |
| Tuesday, July 6 |
| » Defeated Padres (42-39), 4-0 | Wrigley Field (17-20) | 33-46 | Won 3 |
| » W: Steve Stone (1-0) L: Alan Foster (3-5) S: Bruce Sutter (3) | Fifth | 20½ out |
| Wednesday, July 7 |
| » Defeated Padres (42-40), 10-0 | Wrigley Field (18-20) | 34-46 | Won 4 |
| » W: Rick Reuschel (8-6) L: Dave Freisleben (6-4) | Fifth | 19½ out |
| Thursday, July 8 |
| » Lost to Padres (43-40), 6-3 | Wrigley Field (18-21) | 34-47 | |
| » W: Randy Jones (16-3) L: Bill Bonham (6-7) | Fifth | 20 out |
| Friday, July 9 |
| » Defeated Giants (34-51), 5-3 | Wrigley Field (19-21) | 35-47 | |
| » W: Bruce Sutter (1-1) L: Rob Dressler (2-7) | Fifth | 20 out |
| Saturday, July 10 |
| » Defeated Giants (34-52), 8-6 | Wrigley Field (20-21) | 36-47 | Won 2 |
| » W: Darold Knowles (3-3) L: Randy Moffitt (4-3) | Fifth | 20½ out |
| Sunday, July 11 |
| » Lost to Giants (35-52), 2-0 | Wrigley Field (20-22) | 36-48 | |
| » W: Ed Halicki (8-11) L: Steve Stone (1-1) | Fifth | 21½ out |
| Thursday, July 15 |
| » Lost to Dodgers (48-39), 5-2 | Dodger Stadium (1-3) | 36-49 | Lost 2 |
| » W: Doug Rau (8-6) L: Rick Reuschel (8-7) | Fifth | 22½ out |
| Friday, July 16 |
| » Lost to Dodgers (49-39), 4-1 | Dodger Stadium (1-4) | 36-50 | Lost 3 |
| » W: Don Sutton (10-8) L: Steve Renko (3-5) | Fifth | 22½ out |
| Saturday, July 17 |
| » Lost to Dodgers (50-39), 5-4 | Dodger Stadium (1-5) | 36-51 | Lost 4 |
| » W: Rick Rhoden (9-0) L: Steve Stone (1-2) | Fifth | 22½ out |
| Sunday, July 18 |
| » Lost to Padres (44-47), 2-1 | San Diego/Jack Murphy Stadium (2-3) | 36-52 | Lost 5 |
| » W: Butch Metzger (6-0) L: Ray Burris (4-11) | Fifth | 23½ out |
| Monday, July 19 |
| » Lost to Padres (45-47), 3-2 | San Diego/Jack Murphy Stadium (2-4) | 36-53 | Lost 6 |
| » W: Brent Strom (9-10) L: Bill Bonham (6-8) | Fifth | 24½ out |
| Tuesday, July 20 |
| » Defeated Giants (39-55), 3-2 | Candlestick Park (4-1) | 37-53 | |
| » W: Rick Reuschel (9-7) L: Ed Halicki (9-12) S: Darold Knowles (8) | Fifth | 23½ out |
| Wednesday, July 21 |
| » Lost to Giants (40-55), 2-1 | Candlestick Park (4-2) | 37-54 | |
| » W: John Montefusco (9-8) L: Bruce Sutter (1-2) | Fifth | 24½ out |
| Thursday, July 22 |
| » Defeated Cardinals (40-51), 8-4 | Busch Stadium II (3-1) | 38-54 | |
| » W: Steve Stone (2-2) L: Pete Falcone (6-10) S: Joe Coleman (2) | Fifth | 24½ out |
| Friday, July 23 |
| » Defeated Cardinals (40-52), 4-3 | Busch Stadium II (4-1) | 39-54 | Won 2 |
| » W: Ray Burris (5-11) L: Eric Rasmussen (3-8) S: Bruce Sutter (4) | Fifth | 24½ out |
| Saturday, July 24 |
| » Lost to Cardinals (41-52), 12-3 | Busch Stadium II (4-2) | 39-55 | |
| » W: Bob Forsch (5-5) L: Bill Bonham (6-9) | Fifth | 25 out |
| Sunday, July 25 |
| » Lost to Cardinals (42-52), 4-3 | Busch Stadium II (4-3) | 39-56 | Lost 2 |
| » W: Lynn McGlothen (9-9) L: Rick Reuschel (9-8) S: Al Hrabosky (10) | Fifth | 26 out |
| Monday, July 26 |
| » Lost to Expos (31-59), 2-1 | Wrigley Field (20-23) | 39-57 | Lost 3 |
| » W: Don Stanhouse (7-4) L: Steve Stone (2-3) | Fifth | 27½ out |
| » Lost to Expos (32-59), 3-1 | Wrigley Field (20-24) | 39-58 | Lost 4 |
| » W: Steve Dunning (1-4) L: Steve Renko (3-6) S: Dale Murray (10) | Fifth | 27½ out |
| Tuesday, July 27 |
| » Defeated Expos (32-60), 5-0 | Wrigley Field (21-24) | 40-58 | |
| » W: Ray Burris (6-11) L: Steve Rogers (3-10) | Fifth | 26½ out |
| Wednesday, July 28 |
| » Defeated Phillies (65-31), 5-2 | Veteran's Stadium (2-2) | 41-58 | Won 2 |
| » W: Bruce Sutter (2-2) L: Ron Reed (8-4) | Fifth | 25½ out |
| Thursday, July 29 |
| » Lost to Phillies (66-31), 3-2 | Veteran's Stadium (2-3) | 41-59 | |
| » W: Gene Garber (5-2) L: Darold Knowles (3-4) | Fifth | 26½ out |
| Friday, July 30 |
| » Defeated Cardinals (42-55), 7-6 | Wrigley Field (22-24) | 42-59 | |
| » W: Paul Reuschel (2-2) L: Bob Forsch (5-6) S: Darold Knowles (9) | Fifth | 25½ out |
| Saturday, July 31 |
| » Defeated Cardinals (42-56), 6-2 | Wrigley Field (23-24) | 43-59 | Won 2 |
| » W: Steve Renko (4-6) L: Lynn McGlothen (9-10) | Fifth | 25½ out |
| Sunday, August 1 |
| » Defeated Cardinals (42-57), 2-1 | Wrigley Field (24-24) | 44-59 | Won 3 |
| » W: Ray Burris (7-11) L: John Denny (5-5) | Fourth | 26 out |
| Monday, August 2 |
| » Defeated Phillies (69-33), 4-2 | Wrigley Field (25-24) | 45-59 | Won 4 |
| » W: Bill Bonham (7-9) L: Jim Lonborg (12-6) S: Joe Coleman (3) | Fourth | 25 out |
| Tuesday, August 3 |
| » Defeated Phillies (69-34), 4-0 | Wrigley Field (26-24) | 46-59 | Won 5 |
| » W: Rick Reuschel (10-8) L: Jim Kaat (10-6) | Fourth | 25 out |
| » Lost to Phillies (70-34), 8-5 | Wrigley Field (26-25) | 46-60 | |
| » W: Steve Carlton (12-4) L: Steve Stone (2-4) S: Ron Reed (8) | Fourth | 25 out |
| Wednesday, August 4 |
| » Lost to Phillies (71-34), 7-5 | Wrigley Field (26-26) | 46-61 | Lost 2 |
| » W: Gene Garber (7-2) L: Joe Coleman (2-10) | Fourth | 26 out |
| Thursday, August 5 |
| » Defeated Expos (36-64), 4-3 | Parc Jarry (1-1) | 47-61 | |
| » W: Ray Burris (8-11) L: Don Stanhouse (7-5) S: Bruce Sutter (5) | Fourth | 26 out |
| Friday, August 6 |
| » Defeated Expos (36-65), 6-5 | Parc Jarry (2-1) | 48-61 | Won 2 |
| » W: Paul Reuschel (3-2) L: Chuck Taylor (1-1) | Fourth | 24½ out |
| » Defeated Expos (36-66), 1-0 | Parc Jarry (3-1) | 49-61 | Won 3 |
| » W: Steve Stone (3-4) L: Joe Kerrigan (0-3) | Fourth | 24½ out |
| Saturday, August 7 |
| » Defeated Expos (36-67), 4-3 | Parc Jarry (4-1) | 50-61 | Won 4 |
| » W: Darold Knowles (4-4) L: Joe Kerrigan (0-4) | Fourth | 24 out |
| » Lost to Expos (37-67), 7-2 | Parc Jarry (4-2) | 50-62 | |
| » W: Steve Dunning (2-4) L: Oscar Zamora (5-3) | Fourth | 24 out |
| Sunday, August 8 |
| » Defeated Expos (37-68), 7-1 | Parc Jarry (5-2) | 51-62 | |
| » W: Steve Renko (5-6) L: Chip Lang (1-2) | Fourth | 24 out |
| Monday, August 9 |
| » Major-league debuts: Garry Templeton (Cardinals) |
| Tuesday, August 10 |
| » Defeated Reds (73-40), 6-3 | Wrigley Field (27-26) | 52-62 | Won 2 |
| » W: Ray Burris (9-11) L: Gary Nolan (10-7) S: Bruce Sutter (6) | Fourth | 23 out |
| Wednesday, August 11 |
| » Lost to Reds (74-40), 13-10 | Wrigley Field (27-27) | 52-63 | |
| » W: Pat Zachry (11-3) L: Darold Knowles (4-5) | Fourth | 24 out |
| Thursday, August 12 |
| » Lost to Reds (75-40), 8-3 | Wrigley Field (27-28) | 52-64 | Lost 2 |
| » W: Manny Sarmiento (2-0) L: Bruce Sutter (2-3) S: Rawly Eastwick (15) | Fourth | 24 out |
| Friday, August 13 |
| » Defeated Dodgers (61-53), 3-2 | Wrigley Field (28-28) | 53-64 | |
| » W: Joe Coleman (3-10) L: Charlie Hough (9-5) | Fourth | 23½ out |
| » Lost to Dodgers (62-53), 8-7 | Wrigley Field (28-29) | 53-65 | |
| » W: Al Downing (1-1) L: Darold Knowles (4-6) | Fourth | 23½ out |
| Saturday, August 14 |
| » Defeated Dodgers (62-54), 2-0 | Wrigley Field (29-29) | 54-65 | |
| » W: Ray Burris (10-11) L: Doug Rau (10-10) | Fourth | 23½ out |
| Sunday, August 15 |
| » Lost to Dodgers (63-54), 3-2 | Wrigley Field (29-30) | 54-66 | |
| » W: Don Sutton (14-9) L: Bill Bonham (7-10) | Fourth | 23½ out |
| Monday, August 16 |
| » Defeated Astros (58-64), 5-3 | Astrodome (1-4) | 55-66 | |
| » W: Bruce Sutter (3-3) L: Larry Dierker (12-11) | Fourth | 23 out |
| Tuesday, August 17 |
| » Lost to Astros (59-64), 8-1 | Astrodome (1-5) | 55-67 | |
| » W: J.R. Richard (14-12) L: Steve Stone (3-5) | Fourth | 24 out |
| Friday, August 20 |
| » Lost to Reds (79-44), 4-3 | Riverfront Stadium (1-3) | 55-68 | Lost 2 |
| » W: Gary Nolan (11-8) L: Ray Burris (10-12) S: Rawly Eastwick (17) | Fourth | 25 out |
| Saturday, August 21 |
| » Defeated Reds (79-45), 3-2 | Riverfront Stadium (2-3) | 56-68 | |
| » W: Rick Reuschel (11-8) L: Fred Norman (11-4) S: Bruce Sutter (7) | Fourth | 25 out |
| Sunday, August 22 |
| » Lost to Reds (80-45), 4-3 | Riverfront Stadium (2-4) | 56-69 | |
| » W: Manny Sarmiento (3-1) L: Joe Coleman (3-11) S: Rawly Eastwick (18) | Fourth | 26 out |
| Monday, August 23 |
| Future Cub Cole Liniak is born in Encinitas, CA. |
| Tuesday, August 24 |
| » Lost to Astros (61-67), 4-3 | Wrigley Field (29-31) | 56-70 | Lost 2 |
| » W: Joaquin Andujar (7-9) L: Steve Renko (5-7) S: Bo McLaughlin (1) | Fifth | 27½ out |
| Wednesday, August 25 |
| » Defeated Astros (61-68), 5-1 | Wrigley Field (30-31) | 57-70 | |
| » W: Ray Burris (11-12) L: Dan Larson (3-5) | Fifth | 26½ out |
| Thursday, August 26 |
| » Lost to Astros (62-68), 5-3 | Wrigley Field (30-32) | 57-71 | |
| » W: J.R. Richard (15-13) L: Rick Reuschel (11-9) S: Ken Forsch (17) | Fifth | 27½ out |
| Friday, August 27 |
| » Defeated Braves (58-71), 9-4 | Wrigley Field (31-32) | 58-71 | |
| » W: Bill Bonham (8-10) L: Frank LaCorte (1-8) | Fifth | 26½ out |
| Saturday, August 28 |
| » Defeated Braves (58-72), 5-2 | Wrigley Field (32-32) | 59-71 | Won 2 |
| » W: Steve Renko (6-7) L: Dick Ruthven (13-13) S: Bruce Sutter (8) | Fourth | 25½ out |
| Sunday, August 29 |
| » Defeated Braves (58-73), 3-2 | Wrigley Field (33-32) | 60-71 | Won 3 |
| » W: Ray Burris (12-12) L: Phil Niekro (14-10) | Fourth | 24½ out |
| Tuesday, August 31 |
| » Lost to Braves (59-73), 5-3 | Atlanta-Fulton County Stadium (1-4) | 60-72 | |
| » W: Frank LaCorte (2-8) L: Rick Reuschel (11-10) S: Adrian Devine (6) | Fourth | 24 out |
| Wednesday, September 1 |
| » Defeated Braves (59-74), 7-5 | Atlanta-Fulton County Stadium (2-4) | 61-72 | |
| » W: Darold Knowles (5-6) L: Buzz Capra (0-1) S: Paul Reuschel (3) | Fourth | 23 out |
| Friday, September 3 |
| » Defeated Cardinals (57-71), 8-5 | Wrigley Field (34-32) | 62-72 | Won 2 |
| » W: Bruce Sutter (4-3) L: Eddie Solomon (0-1) | Fourth | 22 out |
| Saturday, September 4 |
| » Defeated Cardinals (57-72), 5-1 | Wrigley Field (35-32) | 63-72 | Won 3 |
| » W: Steve Renko (7-7) L: Lynn McGlothen (11-13) S: Bruce Sutter (9) | Fourth | 21 out |
| Sunday, September 5 |
| » Lost to Cardinals (58-72), 1-0 | Wrigley Field (35-33) | 63-73 | |
| » W: Al Hrabosky (8-6) L: Joe Coleman (3-12) | Fourth | 22 out |
| Monday, September 6 |
| » Lost to Mets (70-66), 7-4 | Wrigley Field (35-34) | 63-74 | Lost 2 |
| » W: Jerry Koosman (18-8) L: Steve Stone (3-6) | Fourth | 21½ out |
| » Major-league debuts: Mike Krukow (Cubs) |
| Tuesday, September 7 |
| » Lost to Mets (71-66), 11-0 | Wrigley Field (35-35) | 63-75 | Lost 3 |
| » W: Jon Matlack (15-8) L: Ray Burris (12-13) | Fourth | 22 out |
| » Major-league debuts: Lee Mazzilli (Mets) |
| Wednesday, September 8 |
| » Lost to Mets (72-66), 11-5 | Wrigley Field (35-36) | 63-76 | Lost 4 |
| » W: Tom Seaver (12-10) L: Steve Renko (7-8) S: Skip Lockwood (16) | Fourth | 22 out |
| Thursday, September 9 |
| » Lost to Phillies (85-53), 4-2 | Veteran's Stadium (2-4) | 63-77 | Lost 5 |
| » W: Jim Lonborg (15-9) L: Bill Bonham (8-11) | Fourth | 23 out |
| » Major-league debuts: Rick Bosetti (Phillies) |
| Friday, September 10 |
| » Defeated Phillies (85-54), 3-2 | Veteran's Stadium (3-4) | 64-77 | |
| » W: Rick Reuschel (12-10) L: Jim Kaat (11-12) | Fourth | 22 out |
| Saturday, September 11 |
| » Defeated Phillies (85-55), 4-1 | Veteran's Stadium (4-4) | 65-77 | Won 2 |
| » W: Bruce Sutter (5-3) L: Ron Reed (8-5) S: Joe Coleman (4) | Fourth | 21 out |
| Sunday, September 12 |
| » Lost to Phillies (86-55), 8-0 | Veteran's Stadium (4-5) | 65-78 | |
| » W: Larry Christenson (12-8) L: Steve Renko (7-9) S: Tug McGraw (9) | Fourth | 22 out |
| Monday, September 13 |
| » Lost to Cardinals (63-77), 4-3 | Busch Stadium II (4-4) | 65-79 | Lost 2 |
| » W: Bob Forsch (6-10) L: Bill Bonham (8-12) | Fourth | 23 out |
| Tuesday, September 14 |
| » Defeated Cardinals (63-78), 6-3 | Busch Stadium II (5-4) | 66-79 | |
| » W: Rick Reuschel (13-10) L: Lynn McGlothen (12-14) | Fourth | 23 out |
| Wednesday, September 15 |
| » Defeated Expos (48-94), 2-0 | Parc Jarry (6-2) | 67-79 | Won 2 |
| » W: Ray Burris (13-13) L: Steve Rogers (6-16) | Fourth | 22 out |
| Thursday, September 16 |
| » Lost to Expos (49-94), 4-3 | Parc Jarry (6-3) | 67-80 | |
| » W: Larry Landreth (1-0) L: Steve Renko (7-10) S: Dale Murray (13) | Fourth | 22 out |
| Friday, September 17 |
| » Defeated Phillies (88-58), 4-3 | Wrigley Field (36-36) | 68-80 | |
| » W: Bruce Sutter (6-3) L: Ron Reed (8-7) | Fourth | 21 out |
| Saturday, September 18 |
| » Lost to Phillies (89-58), 4-1 | Wrigley Field (36-37) | 68-81 | |
| » W: Steve Carlton (18-6) L: Rick Reuschel (13-11) | Fifth | 22 out |
| Sunday, September 19 |
| » Defeated Phillies (89-59), 1-0 | Wrigley Field (37-37) | 69-81 | |
| » W: Ray Burris (14-13) L: Jim Lonborg (16-10) | Fourth | 21 out |
| Tuesday, September 21 |
| » Lost to Pirates (86-64), 4-3 | Wrigley Field (37-38) |