| Saturday, January 10 |
| Future Cardinal Adam Kennedy is born in Riverside, CA. |
| Friday, April 9 |
| » Defeated Cubs (0-1), 5-0 | Busch Stadium II (1-0) | 1-0 | |
| » W: Lynn McGlothen (1-0) L: Ray Burris (0-1) | First | -- |
| Saturday, April 10 |
| » Lost to Cubs (1-1), 4-3 | Busch Stadium II (1-1) | 1-1 | |
| » W: Bill Bonham (1-0) L: Eric Rasmussen (0-1) S: Darold Knowles (1) | Third | 1 out |
| » Major-league debuts: Mike Proly (Cardinals) |
| Sunday, April 11 |
| » Lost to Cubs (2-1), 8-5 | Busch Stadium II (1-2) | 1-2 | Lost 2 |
| » W: Darold Knowles (1-0) L: Jack Curtis (0-1) | Third | 1½ out |
| Tuesday, April 13 |
| » Lost to Pirates (3-0), 14-4 | Three Rivers Stadium (0-1) | 1-3 | Lost 3 |
| » W: Jerry Reuss (1-0) L: Pete Falcone (0-1) | Fifth | 2½ out |
| Thursday, April 15 |
| » Lost to Pirates (4-0), 9-3 | Three Rivers Stadium (0-2) | 1-4 | Lost 4 |
| » W: Jim Rooker (1-0) L: Lynn McGlothen (1-1) S: Ramon Hernandez (1) | Sixth | 3½ out |
| Saturday, April 17 |
| » Defeated Expos (2-4), 4-3 | Busch Stadium II (2-2) | 2-4 | |
| » W: Eric Rasmussen (1-1) L: Fred Scherman (1-1) | Fifth | 3 out |
| Sunday, April 18 |
| » Defeated Expos (2-5), 2-1 | Busch Stadium II (3-2) | 3-4 | Won 2 |
| » W: John Denny (1-0) L: Dan Warthen (0-1) S: Mike Wallace (1) | Fifth | 3 out |
| Monday, April 19 |
| » Lost to Mets (5-5), 4-3 | Busch Stadium II (3-3) | 3-5 | |
| » W: Bob Apodaca (1-0) L: Mike Wallace (0-1) | Fifth | 3½ out |
| Tuesday, April 20 |
| » Lost to Mets (6-5), 8-0 | Busch Stadium II (3-4) | 3-6 | Lost 2 |
| » W: Jon Matlack (2-0) L: Lynn McGlothen (1-2) | Sixth | 3½ out |
| Wednesday, April 21 |
| » Defeated Mets (6-6), 7-4 | Busch Stadium II (4-4) | 4-6 | |
| » W: Eric Rasmussen (2-1) L: Mickey Lolich (0-3) S: Al Hrabosky (1) | Fifth | 2½ out |
| Friday, April 23 |
| » Lost to Padres (6-6), 5-1 | San Diego/Jack Murphy Stadium (0-1) | 4-7 | |
| » W: Randy Jones (4-0) L: John Denny (1-1) | Sixth | 2½ out |
| Saturday, April 24 |
| » Lost to Padres (7-6), 4-3 | San Diego/Jack Murphy Stadium (0-2) | 4-8 | Lost 2 |
| » W: Butch Metzger (2-0) L: Eric Rasmussen (2-2) | Sixth | 3 out |
| Sunday, April 25 |
| » Defeated Padres (7-7), 3-1 | San Diego/Jack Murphy Stadium (1-2) | 5-8 | |
| » W: Jack Curtis (1-1) L: Dan Spillner (0-3) | Fifth | 2½ out |
| Monday, April 26 |
| » Defeated Giants (7-7), 15-7 | Candlestick Park (1-0) | 6-8 | Won 2 |
| » W: Mike Wallace (1-1) L: Greg Minton (0-1) S: Al Hrabosky (2) | Fourth | 2 out |
| Tuesday, April 27 |
| » Defeated Giants (7-8), 7-1 | Candlestick Park (2-0) | 7-8 | Won 3 |
| » W: Lynn McGlothen (2-2) L: John D'Acquisto (0-1) | Fourth | 2 out |
| Wednesday, April 28 |
| » Defeated Giants (7-9), 4-2 | Candlestick Park (3-0) | 8-8 | Won 4 |
| » W: Mike Proly (1-0) L: Mike Caldwell (0-3) S: Danny Frisella (1) | Third | 2 out |
| Thursday, April 29 |
| » Lost to Dodgers (9-9), 4-0 | Dodger Stadium (0-1) | 8-9 | |
| » W: Don Sutton (2-3) L: Pete Falcone (0-2) | Third | 3 out |
| Friday, April 30 |
| » Lost to Dodgers (10-9), 5-1 | Dodger Stadium (0-2) | 8-10 | Lost 2 |
| » W: Rick Rhoden (2-0) L: Jack Curtis (1-2) | Fifth | 4 out |
| Saturday, May 1 |
| » Lost to Dodgers (11-9), 4-3 | Dodger Stadium (0-3) | 8-11 | Lost 3 |
| » W: Mike Marshall (1-1) L: Al Hrabosky (0-1) | Fifth | 4½ out |
| Sunday, May 2 |
| » Lost to Dodgers (12-9), 3-1 | Dodger Stadium (0-4) | 8-12 | Lost 4 |
| » W: Doug Rau (4-0) L: Lynn McGlothen (2-3) | Fifth | 4½ out |
| Tuesday, May 4 |
| » Defeated Braves (8-13), 8-7 | Atlanta-Fulton County Stadium (1-0) | 9-12 | |
| » W: Eric Rasmussen (3-2) L: Adrian Devine (0-1) | Fifth | 4½ out |
| Wednesday, May 5 |
| » Defeated Braves (8-14), 4-0 | Atlanta-Fulton County Stadium (2-0) | 10-12 | Won 2 |
| » W: Pete Falcone (1-2) L: Dick Ruthven (3-3) S: Al Hrabosky (3) | Fifth | 4½ out |
| Thursday, May 6 |
| » Defeated Braves (8-15), 5-4 | Atlanta-Fulton County Stadium (3-0) | 11-12 | Won 3 |
| » W: Jack Curtis (2-2) L: Carl Morton (0-4) S: Al Hrabosky (4) | Fourth | 4 out |
| Friday, May 7 |
| » Lost to Astros (13-13), 3-1 | Busch Stadium II (4-5) | 11-13 | |
| » W: J.R. Richard (5-1) L: Bob Forsch (0-1) | Fourth | 5 out |
| Saturday, May 8 |
| » Defeated Astros (13-14), 5-1 | Busch Stadium II (5-5) | 12-13 | |
| » W: Lynn McGlothen (3-3) L: Mike Cosgrove (1-1) | Fourth | 5 out |
| Sunday, May 9 |
| » Lost to Astros (14-14), 10-5 | Busch Stadium II (5-6) | 12-14 | |
| » W: Larry Dierker (4-3) L: John Denny (1-2) | Fourth | 5 out |
| Monday, May 10 |
| » Lost to Dodgers (16-11), 4-3 | Busch Stadium II (5-7) | 12-15 | Lost 2 |
| » W: Mike Marshall (2-1) L: Eric Rasmussen (3-3) | Fourth | 5½ out |
| Tuesday, May 11 |
| » Lost to Dodgers (17-11), 4-0 | Busch Stadium II (5-8) | 12-16 | Lost 3 |
| » W: Don Sutton (4-3) L: Jack Curtis (2-3) | Fourth | 6½ out |
| Wednesday, May 12 |
| » Lost to Dodgers (18-11), 6-3 | Busch Stadium II (5-9) | 12-17 | Lost 4 |
| » W: Mike Marshall (3-1) L: Eric Rasmussen (3-4) | Fifth | 6½ out |
| Friday, May 14 |
| » Defeated Giants (10-20), 3-1 | Busch Stadium II (6-9) | 13-17 | |
| » W: Lynn McGlothen (4-3) L: John Montefusco (4-2) S: Al Hrabosky (5) | Fourth | 6½ out |
| Saturday, May 15 |
| » Lost to Giants (11-20), 2-0 | Busch Stadium II (6-10) | 13-18 | |
| » W: Gary Lavelle (2-1) L: Al Hrabosky (0-2) | Fourth | 7½ out |
| Future Cardinal Jason Karnuth is born in LaGrange, IL. |
| Sunday, May 16 |
| » Defeated Giants (11-21), 9-3 | Busch Stadium II (7-10) | 14-18 | |
| » W: Pete Falcone (2-2) L: Ed Halicki (2-6) | Fourth | 7½ out |
| Monday, May 17 |
| » Lost to Pirates (18-12), 2-1 | Busch Stadium II (7-11) | 14-19 | |
| » W: Bruce Kison (3-3) L: Jack Curtis (2-4) S: Bob Moose (5) | Fifth | 8 out |
| Tuesday, May 18 |
| » Lost to Pirates (19-12), 4-1 | Busch Stadium II (7-12) | 14-20 | Lost 2 |
| » W: Jim Rooker (5-1) L: Al Hrabosky (0-3) | Sixth | 8½ out |
| Wednesday, May 19 |
| » Lost to Pirates (20-12), 7-6 | Busch Stadium II (7-13) | 14-21 | Lost 3 |
| » W: Ramon Hernandez (1-0) L: Eric Rasmussen (3-5) S: Bob Moose (6) | Sixth | 9½ out |
| Thursday, May 20 |
| » Defeated Pirates (20-13), 4-1 | Busch Stadium II (8-13) | 15-21 | |
| » W: John Denny (2-2) L: Doc Medich (3-4) | Sixth | 9½ out |
| Friday, May 21 |
| » Lost to Phillies (22-8), 2-1 | Veteran's Stadium (0-1) | 15-22 | |
| » W: Steve Carlton (4-1) L: Pete Falcone (2-3) | Sixth | 10½ out |
| Saturday, May 22 |
| » Defeated Phillies (22-9), 7-6 | Veteran's Stadium (1-1) | 16-22 | |
| » W: Al Hrabosky (1-3) L: Tug McGraw (2-3) | Fifth | 9½ out |
| Sunday, May 23 |
| » Lost to Phillies (23-9), 3-2 | Veteran's Stadium (1-2) | 16-23 | |
| » W: Tug McGraw (3-3) L: Al Hrabosky (1-4) | Sixth | 10½ out |
| Tuesday, May 25 |
| » Defeated Cubs (16-22), 5-2 | Wrigley Field (1-0) | 17-23 | |
| » W: Lynn McGlothen (5-3) L: Ray Burris (1-6) | Fifth | 11 out |
| Wednesday, May 26 |
| » Lost to Cubs (17-22), 4-2 | Wrigley Field (1-1) | 17-24 | |
| » W: Rick Reuschel (4-3) L: John Denny (2-3) S: Darold Knowles (4) | Sixth | 12 out |
| Thursday, May 27 |
| » Lost to Cubs (18-22), 2-1 | Wrigley Field (1-2) | 17-25 | Lost 2 |
| » W: Steve Renko (1-1) L: Pete Falcone (2-4) S: Darold Knowles (5) | Sixth | 12 out |
| Friday, May 28 |
| » Defeated Mets (23-21), 6-0 | Shea Stadium (1-0) | 18-25 | |
| » W: Jack Curtis (3-4) L: Craig Swan (2-4) | Sixth | 12 out |
| » Major-league debuts: Bob Myrick (Mets) |
| Saturday, May 29 |
| » Defeated Mets (23-22), 3-2 | Shea Stadium (2-0) | 19-25 | Won 2 |
| » W: Al Hrabosky (2-4) L: Ken Sanders (1-1) | Fifth | 12 out |
| Sunday, May 30 |
| » Defeated Mets (23-23), 6-5 | Shea Stadium (3-0) | 20-25 | Won 3 |
| » W: Al Hrabosky (3-4) L: Skip Lockwood (2-2) | Fifth | 12 out |
| Tuesday, June 1 |
| » Defeated Expos (16-24), 6-2 | Parc Jarry (1-0) | 21-25 | Won 4 |
| » W: Pete Falcone (3-4) L: Dan Warthen (1-5) | Fourth | 12 out |
| Wednesday, June 2 |
| » Lost to Phillies (32-11), 4-1 | Busch Stadium II (8-14) | 21-26 | |
| » W: Tom Underwood (2-1) L: Jack Curtis (3-5) | Fifth | 13 out |
| Thursday, June 3 |
| » Defeated Phillies (32-12), 7-1 | Busch Stadium II (9-14) | 22-26 | |
| » W: Bob Forsch (1-1) L: Larry Christenson (6-2) | Fifth | 12 out |
| Friday, June 4 |
| » Lost to Reds (30-19), 11-2 | Busch Stadium II (9-15) | 22-27 | |
| » W: Gary Nolan (4-3) L: Lynn McGlothen (5-4) | Fifth | 12 out |
| Saturday, June 5 |
| » Lost to Reds (31-19), 5-1 | Busch Stadium II (9-16) | 22-28 | Lost 2 |
| » W: Don Gullett (4-2) L: John Denny (2-4) | Fifth | 12 out |
| Sunday, June 6 |
| » Lost to Reds (32-19), 13-2 | Busch Stadium II (9-17) | 22-29 | Lost 3 |
| » W: Pat Zachry (5-1) L: Pete Falcone (3-5) | Fourth | 13 out |
| Monday, June 7 |
| » Defeated Astros (27-29), 7-6 | Astrodome (1-0) | 23-29 | |
| » W: Jack Curtis (4-5) L: Joe Niekro (3-6) S: Al Hrabosky (6) | Fourth | 13 out |
| Tuesday, June 8 |
| » Lost to Astros (28-29), 2-0 | Astrodome (1-1) | 23-30 | |
| » W: Larry Dierker (6-5) L: Bob Forsch (1-2) | Fourth | 14 out |
| Wednesday, June 9 |
| » Lost to Astros (29-29), 5-2 | Astrodome (1-2) | 23-31 | Lost 2 |
| » W: J.R. Richard (7-5) L: Lynn McGlothen (5-5) | Fourth | 14 out |
| Friday, June 11 |
| » Lost to Reds (36-20), 8-7 | Riverfront Stadium (0-1) | 23-32 | Lost 3 |
| » W: Rawly Eastwick (4-3) L: Al Hrabosky (3-5) | Fifth | 15½ out |
| Former Cardinal Jim Konstanty dies in Oneonta, NY at the age of 60. |
| Saturday, June 12 |
| » Defeated Reds (36-21), 5-4 | Riverfront Stadium (1-1) | 24-32 | |
| » W: Pete Falcone (4-5) L: Jack Billingham (5-4) S: Bill Greif (1) | Fifth | 15½ out |
| Sunday, June 13 |
| » Lost to Reds (37-21), 4-0 | Riverfront Stadium (1-2) | 24-33 | |
| » W: Fred Norman (4-1) L: Jack Curtis (4-6) S: Will McEnaney (3) | Fifth | 14½ out |
| » Defeated Reds (37-22), 12-9 | Riverfront Stadium (2-2) | 25-33 | |
| » W: Bob Forsch (2-2) L: Santo Alcala (6-2) | Fifth | 14½ out |
| Monday, June 14 |
| » Lost to Braves (23-34), 5-2 | Busch Stadium II (9-18) | 25-34 | |
| » W: Andy Messersmith (5-5) L: Lynn McGlothen (5-6) | Fifth | 15 out |
| Tuesday, June 15 |
| » Lost to Braves (24-34), 5-4 | Busch Stadium II (9-19) | 25-35 | Lost 2 |
| » W: Dick Ruthven (7-6) L: Eric Rasmussen (3-6) S: Mike Beard (1) | Fifth | 16 out |
| Wednesday, June 16 |
| » Defeated Braves (24-35), 4-3 | Busch Stadium II (10-19) | 26-35 | |
| » W: Al Hrabosky (4-5) L: Mike Beard (0-1) | Fifth | 16 out |
| Friday, June 18 |
| » Defeated Padres (33-28), 7-4 | Busch Stadium II (11-19) | 27-35 | Won 2 |
| » W: Pete Falcone (5-5) L: Randy Jones (12-3) | Fifth | 16½ out |
| Saturday, June 19 |
| » Defeated Padres (33-29), 1-0 | Busch Stadium II (12-19) | 28-35 | Won 3 |
| » W: Jack Curtis (5-6) L: Brent Strom (6-6) S: Bill Greif (2) | Fourth | 15½ out |
| Sunday, June 20 |
| » Lost to Padres (34-29), 5-4 | Busch Stadium II (12-20) | 28-36 | |
| » W: Dan Spillner (2-6) L: Bill Greif (1-4) S: Ken Reynolds (1) | Fourth | 16½ out |
| Former Cardinal Blix Donnelly dies in Olivia, MN at the age of 63. Former Cardinal Lou Klein dies in Metairie, LA at the age of 58. |
| Monday, June 21 |
| » Defeated Mets (33-36), 7-2 | Busch Stadium II (13-20) | 29-36 | |
| » W: Lynn McGlothen (6-6) L: Jerry Koosman (6-6) S: Al Hrabosky (7) | Fourth | 16½ out |
| Tuesday, June 22 |
| » Defeated Mets (33-37), 3-0 | Busch Stadium II (14-20) | 30-36 | Won 2 |
| » W: John Denny (3-4) L: Craig Swan (3-7) | Fourth | 15½ out |
| Wednesday, June 23 |
| » Lost to Mets (34-37), 5-4 | Busch Stadium II (14-21) | 30-37 | |
| » W: Tom Seaver (8-5) L: Pete Falcone (5-6) | Fourth | 16½ out |
| Former Cardinal Lon Warneke dies in Hot Springs, AR at the age of 68. |
| Friday, June 25 |
| » Lost to Phillies (47-19), 12-4 | Veteran's Stadium (1-3) | 30-38 | Lost 2 |
| » W: Larry Christenson (8-3) L: Jack Curtis (5-7) | Fourth | 18 out |
| Saturday, June 26 |
| » Defeated Phillies (47-20), 3-2 | Veteran's Stadium (2-3) | 31-38 | |
| » W: Al Hrabosky (5-5) L: Tug McGraw (4-4) | Fourth | 17 out |
| Sunday, June 27 |
| » Lost to Phillies (48-20), 6-2 | Veteran's Stadium (2-4) | 31-39 | |
| » W: Jim Lonborg (10-4) L: Lynn McGlothen (6-7) S: Ron Reed (1) | Fourth | 18 out |
| Monday, June 28 |
| » Lost to Mets (38-37), 5-4 | Shea Stadium (3-1) | 31-40 | Lost 2 |
| » W: Skip Lockwood (4-2) L: Bill Greif (1-5) S: Bob Apodaca (2) | Fourth | 19 out |
| Tuesday, June 29 |
| » Lost to Mets (39-37), 2-0 | Shea Stadium (3-2) | 31-41 | Lost 3 |
| » W: Mickey Lolich (4-9) L: Pete Falcone (5-7) | Fourth | 20 out |
| Thursday, July 1 |
| » Lost to Mets (40-37), 13-0 | Shea Stadium (3-3) | 31-42 | Lost 4 |
| » W: Jon Matlack (10-2) L: Bob Forsch (2-3) | Fourth | 20½ out |
| Friday, July 2 |
| » Defeated Expos (24-44), 3-0 | Busch Stadium II (15-21) | 32-42 | |
| » W: Lynn McGlothen (7-7) L: Woodie Fryman (8-6) | Fourth | 19½ out |
| Saturday, July 3 |
| » Defeated Expos (24-45), 9-0 | Busch Stadium II (16-21) | 33-42 | Won 2 |
| » W: John Denny (4-4) L: Steve Rogers (2-6) | Fourth | 19½ out |
| Sunday, July 4 |
| » Lost to Expos (25-45), 4-3 | Busch Stadium II (16-22) | 33-43 | |
| » W: Don Stanhouse (6-3) L: Pete Falcone (5-8) S: Dale Murray (8) | Fourth | 20 out |
| Monday, July 5 |
| » Lost to Giants (33-49), 6-4 | Busch Stadium II (16-23) | 33-44 | Lost 2 |
| » W: Gary Lavelle (3-4) L: Eric Rasmussen (3-7) | Fourth | 20 out |
| Tuesday, July 6 |
| » Defeated Giants (33-50), 13-7 | Busch Stadium II (17-23) | 34-44 | |
| » W: Bob Forsch (3-3) L: Ed Halicki (7-11) | Fourth | 19 out |
| Wednesday, July 7 |
| » Lost to Giants (34-50), 3-2 | Busch Stadium II (17-24) | 34-45 | |
| » W: Gary Lavelle (4-4) L: Lynn McGlothen (7-8) | Fourth | 19 out |
| Friday, July 9 |
| » Defeated Dodgers (46-38), 4-3 | Busch Stadium II (18-24) | 35-45 | |
| » W: Bill Greif (2-5) L: Elias Sosa (4-5) | Fourth | 19 out |
| Saturday, July 10 |
| » Defeated Dodgers (46-39), 6-3 | Busch Stadium II (19-24) | 36-45 | Won 2 |
| » W: Pete Falcone (6-8) L: Tommy John (5-6) | Fourth | 19½ out |
| Sunday, July 11 |
| » Lost to Dodgers (47-39), 9-6 | Busch Stadium II (19-25) | 36-46 | |
| » W: Don Sutton (9-8) L: Bob Forsch (3-4) | Fourth | 20½ out |
| Thursday, July 15 |
| » Defeated Padres (43-45), 2-1 | San Diego/Jack Murphy Stadium (2-2) | 37-46 | |
| » W: Bob Forsch (4-4) L: Brent Strom (8-10) S: Al Hrabosky (8) | Fourth | 20½ out |
| Friday, July 16 |
| » Defeated Padres (43-46), 4-2 | San Diego/Jack Murphy Stadium (3-2) | 38-46 | Won 2 |
| » W: Lynn McGlothen (8-8) L: Randy Jones (16-4) S: Al Hrabosky (9) | Fourth | 19½ out |
| Saturday, July 17 |
| » Defeated Padres (43-47), 7-1 | San Diego/Jack Murphy Stadium (4-2) | 39-46 | Won 3 |
| » W: John Denny (5-4) L: Dave Freisleben (6-6) | Fourth | 18½ out |
| Sunday, July 18 |
| » Lost to Giants (38-53), 5-4 | Candlestick Park (3-1) | 39-47 | |
| » W: Jim Barr (7-6) L: Pete Falcone (6-9) S: Gary Lavelle (9) | Fourth | 19 out |
| » Defeated Giants (38-54), 5-4 | Candlestick Park (4-1) | 40-47 | |
| » W: Mike Wallace (2-1) L: Dave Heaverlo (3-1) | Fourth | 19 out |
| Monday, July 19 |
| » Lost to Giants (39-54), 5-3 | Candlestick Park (4-2) | 40-48 | |
| » W: John D'Acquisto (1-5) L: Bob Forsch (4-5) | Fourth | 20 out |
| Tuesday, July 20 |
| » Lost to Dodgers (51-41), 3-2 | Dodger Stadium (0-5) | 40-49 | Lost 2 |
| » W: Doug Rau (9-6) L: Lynn McGlothen (8-9) | Fourth | 20 out |
| Wednesday, July 21 |
| » Lost to Dodgers (52-41), 7-6 | Dodger Stadium (0-6) | 40-50 | Lost 3 |
| » W: Charlie Hough (8-4) L: Al Hrabosky (5-6) | Fourth | 21 out |
| Future Cardinal Luis Saturria is born in San Pedro de Macoris, D.R. |
| Thursday, July 22 |
| » Lost to Cubs (38-54), 8-4 | Busch Stadium II (19-26) | 40-51 | Lost 4 |
| » W: Steve Stone (2-2) L: Pete Falcone (6-10) S: Joe Coleman (2) | Fourth | 22 out |
| Friday, July 23 |
| » Lost to Cubs (39-54), 4-3 | Busch Stadium II (19-27) | 40-52 | Lost 5 |
| » W: Ray Burris (5-11) L: Eric Rasmussen (3-8) S: Bruce Sutter (4) | Fourth | 23 out |
| Saturday, July 24 |
| » Defeated Cubs (39-55), 12-3 | Busch Stadium II (20-27) | 41-52 | |
| » W: Bob Forsch (5-5) L: Bill Bonham (6-9) | Fourth | 22½ out |
| Sunday, July 25 |
| » Defeated Cubs (39-56), 4-3 | Busch Stadium II (21-27) | 42-52 | Won 2 |
| » W: Lynn McGlothen (9-9) L: Rick Reuschel (9-8) S: Al Hrabosky (10) | Fourth | 22½ out |
| Tuesday, July 27 |
| » Lost to Pirates (53-43), 3-1 | Busch Stadium II (21-28) | 42-53 | |
| » W: Bruce Kison (8-6) L: Pete Falcone (6-11) | Fourth | 23 out |
| Wednesday, July 28 |
| » Lost to Expos (33-60), 3-0 | Busch Stadium II (21-29) | 42-54 | Lost 2 |
| » W: Woodie Fryman (9-8) L: Eric Rasmussen (3-9) S: Dale Murray (11) | Fourth | 23 out |
| Friday, July 30 |
| » Lost to Cubs (42-59), 7-6 | Wrigley Field (1-3) | 42-55 | Lost 3 |
| » W: Paul Reuschel (2-2) L: Bob Forsch (5-6) S: Darold Knowles (9) | Fourth | 23½ out |
| Former Cardinal Jack Knight dies in San Antonio, TX at the age of 82. |
| Saturday, July 31 |
| » Lost to Cubs (43-59), 6-2 | Wrigley Field (1-4) | 42-56 | Lost 4 |
| » W: Steve Renko (4-6) L: Lynn McGlothen (9-10) | Fourth | 24½ out |
| Sunday, August 1 |
| » Lost to Cubs (44-59), 2-1 | Wrigley Field (1-5) | 42-57 | Lost 5 |
| » W: Ray Burris (7-11) L: John Denny (5-5) | Fifth | 26 out |
| Future Cardinal Kevin Joseph is born in Camp Hill, PA. |
| Monday, August 2 |
| » Defeated Pirates (56-46), 4-0 | Three Rivers Stadium (1-2) | 43-57 | |
| » W: Pete Falcone (7-11) L: Doc Medich (5-10) | Fifth | 25 out |
| Tuesday, August 3 |
| » Lost to Pirates (57-46), 2-1 | Three Rivers Stadium (1-3) | 43-58 | |
| » W: Jim Rooker (9-5) L: Bill Greif (2-6) | Fifth | 25 out |
| » Defeated Pirates (57-47), 4-2 | Three Rivers Stadium (2-3) | 44-58 | |
| » W: Al Hrabosky (6-6) L: Dave Giusti (1-3) S: Mike Wallace (2) | Fifth | 25 out |
| Wednesday, August 4 |
| » Lost to Pirates (58-47), 2-1 | Three Rivers Stadium (2-4) | 44-59 | |
| » W: Dave Giusti (2-3) L: Mike Wallace (2-2) | Fifth | 26 out |
| Thursday, August 5 |
| » Lost to Phillies (72-34), 5-2 | Busch Stadium II (21-30) | 44-60 | Lost 2 |
| » W: Wayne Twitchell (2-0) L: Lynn McGlothen (9-11) | Fifth | 27 out |
| Friday, August 6 |
| » Defeated Phillies (72-35), 6-2 | Busch Stadium II (22-30) | 45-60 | |
| » W: John Denny (6-5) L: Jim Lonborg (12-7) S: Al Hrabosky (11) | Fifth | 26 out |
| Saturday, August 7 |
| » Defeated Phillies (72-36), 4-1 | Busch Stadium II (23-30) | 46-60 | Won 2 |
| » W: Pete Falcone (8-11) L: Jim Kaat (10-7) S: Al Hrabosky (12) | Fifth | 25 out |
| Sunday, August 8 |
| » Lost to Phillies (73-36), 3-2 | Busch Stadium II (23-31) | 46-61 | |
| » W: Steve Carlton (13-4) L: Bill Greif (2-7) S: Ron Reed (9) | Fifth | 26 out |
| Monday, August 9 |
| » Lost to Astros (57-58), 13-4 | Busch Stadium II (23-32) | 46-62 | Lost 2 |
| » W: Dan Larson (2-3) L: Bob Forsch (5-7) | Fifth | 26½ out |
| » Major-league debuts: Garry Templeton (Cardinals) |
| Tuesday, August 10 |
| » Defeated Astros (57-59), 8-1 | Busch Stadium II (24-32) | 47-62 | |
| » W: Lynn McGlothen (10-11) L: Bo McLaughlin (1-2) | Fifth | 25½ out |
| Wednesday, August 11 |
| » Lost to Astros (58-59), 8-1 | Busch Stadium II (24-33) | 47-63 | |
| » W: Larry Dierker (12-10) L: John Denny (6-6) | Fifth | 26½ out |
| Friday, August 13 |
| » Defeated Braves (53-63), 8-0 | Atlanta-Fulton County Stadium (4-0) | 48-63 | |
| » W: Pete Falcone (9-11) L: Dick Ruthven (13-10) | Fifth | 25 out |
| Saturday, August 14 |
| » Defeated Braves (53-64), 4-0 | Atlanta-Fulton County Stadium (5-0) | 49-63 | Won 2 |
| » W: Eric Rasmussen (4-9) L: Andy Messersmith (11-10) | Fifth | 25 out |
| Sunday, August 15 |
| » Lost to Braves (54-64), 3-2 | Atlanta-Fulton County Stadium (5-1) | 49-64 | |
| » W: Phil Niekro (13-8) L: Bob Forsch (5-8) | Fifth | 25 out |
| Monday, August 16 |
| » Lost to Padres (60-62), 11-7 | Busch Stadium II (24-34) | 49-65 | Lost 2 |
| » W: Dave Freisleben (8-10) L: Bill Greif (2-8) | Fifth | 25½ out |
| Tuesday, August 17 |
| » Defeated Padres (60-63), 9-4 | Busch Stadium II (25-34) | 50-65 | |
| » W: John Denny (7-6) L: Brent Strom (10-13) S: Jack Curtis (1) | Fifth | 25½ out |
| Wednesday, August 18 |
| » Defeated Padres (60-64), 5-4 | Busch Stadium II (26-34) | 51-65 | Won 2 |
| » W: Pete Falcone (10-11) L: Randy Jones (19-8) S: Bill Greif (3) | Fifth | 25½ out |
| Friday, August 20 |
| » Defeated Braves (56-67), 6-4 | Busch Stadium II (27-34) | 52-65 | Won 3 |
| » W: Eric Rasmussen (5-9) L: Phil Niekro (13-9) S: Bill Greif (4) | Fifth | 25 out |
| Saturday, August 21 |
| » Lost to Braves (57-67), 6-2 | Busch Stadium II (27-35) | 52-66 | |
| » W: Carl Morton (4-9) L: Bob Forsch (5-9) S: Adrian Devine (5) | Fifth | 26 out |
| Sunday, August 22 |
| » Defeated Braves (57-68), 8-0 | Busch Stadium II (28-35) | 53-66 | |
| » W: Lynn McGlothen (11-11) L: Frank LaCorte (1-7) | Fifth | 26 out |
| Monday, August 23 |
| » Defeated Reds (80-46), 9-5 | Riverfront Stadium (3-2) | 54-66 | Won 2 |
| » W: John Denny (8-6) L: Jack Billingham (11-9) | Fourth | 26 out |
| Tuesday, August 24 |
| » Defeated Reds (80-47), 4-1 | Riverfront Stadium (4-2) | 55-66 | Won 3 |
| » W: Pete Falcone (11-11) L: Pat Zachry (11-5) | Fourth | 26 out |
| Friday, August 27 |
| » Lost to Astros (63-68), 2-1 | Astrodome (1-3) | 55-67 | |
| » W: Bo McLaughlin (2-2) L: Eric Rasmussen (5-10) | Fourth | 26 out |
| Saturday, August 28 |
| » Lost to Astros (64-68), 4-3 | Astrodome (1-4) | 55-68 | Lost 2 |
| » W: Larry Dierker (13-12) L: Bob Forsch (5-10) | Fifth | 26 out |
| Sunday, August 29 |
| » Lost to Astros (65-68), 6-0 | Astrodome (1-5) | 55-69 | Lost 3 |
| » W: Joe Sambito (2-1) L: Lynn McGlothen (11-12) | Fifth | 26 out |
| Monday, August 30 |
| » Defeated Reds (83-49), 7-1 | Busch Stadium II (29-35) | 56-69 | |
| » W: John Denny (9-6) L: Will McEnaney (2-5) | Fifth | 25 out |
| Tuesday, August 31 |
| » Lost to Reds (84-49), 6-5 | Busch Stadium II (29-36) | 56-70 | |
| » W: Pedro Borbon (4-2) L: Pete Falcone (11-12) S: Rawly Eastwick (19) | Fifth | 25 out |
| Wednesday, September 1 |
| » Defeated Reds (84-50), 1-0 | Busch Stadium II (30-36) | 57-70 | |
| » W: Al Hrabosky (7-6) L: Rawly Eastwick (9-5) | Fifth | 24 out |
| Friday, September 3 |
| » Lost to Cubs (62-72), 8-5 | Wrigley Field (1-6) | 57-71 | |
| » W: Bruce Sutter (4-3) L: Eddie Solomon (0-1) | Fifth | 24 out |
| Saturday, September 4 |
| » Lost to Cubs (63-72), 5-1 | Wrigley Field (1-7) | 57-72 | Lost 2 |
| » W: Steve Renko (7-7) L: Lynn McGlothen (11-13) S: Bruce Sutter (9) | Fifth | 24 out |
| Sunday, September 5 |
| » Defeated Cubs (63-73), 1-0 | Wrigley Field (2-7) | 58-72 | |
| » W: Al Hrabosky (8-6) L: Joe Coleman (3-12) | Fifth | 24 out |
| Monday, September 6 |
| » Defeated Expos (44-87), 3-1 | Parc Jarry (2-0) | 59-72 | Won 2 |
| » W: Pete Falcone (12-12) L: Steve Rogers (6-14) | Fifth | 23 out |
| » Lost to Expos (45-87), 3-2 | Parc Jarry (2-1) | 59-73 | |
| » W: Chuck Taylor (2-2) L: Jack Curtis (5-8) | Fifth | 23 out |
| Tuesday, September 7 |
| » Defeated Expos (45-88), 7-4 | Parc Jarry (3-1) | 60-73 | |
| » W: Mike Wallace (3-2) L: Chuck Taylor (2-3) S: Bill Greif (5) | Fifth | 22½ out |
| Wednesday, September 8 |
| » Lost to Expos (46-88), 7-5 | Busch Stadium II (30-37) | 60-74 | |
| » W: Joe Kerrigan (1-4) L: Jack Curtis (5-9) S: Dale Murray (12) | Fifth | 23 out |
| » Lost to Expos (47-88), 8-7 | Busch Stadium II (30-38) | 60-75 | Lost 2 |
| » W: Joe Kerrigan (2-4) L: Tom Walker (0-1) S: Woodie Fryman (1) | Fifth | 23 out |
| Thursday, September 9 |
| » Defeated Expos (47-89), 6-1 | Busch Stadium II (31-38) | 61-75 | |
| » W: Lynn McGlothen (12-13) L: Don Carrithers (6-12) | Fifth | 23 out |
| Friday, September 10 |
| » Lost to Mets (73-66), 4-3 | Busch Stadium II (31-39) | 61-76 | |
| » W: Mickey Lolich (8-12) L: John Denny (9-7) S: Bob Apodaca (4) | Fifth | 23 out |
| Saturday, September 11 |
| » Lost to Mets (74-66), 4-1 | Busch Stadium II (31-40) | 61-77 | Lost 2 |
| » W: Jerry Koosman (19-8) L: Pete Falcone (12-13) | Fifth | 23 out |
| Sunday, September 12 |
| » Defeated Mets (74-67), 6-5 | Busch Stadium II (32-40) | 62-77 | |
| » W: Doug Capilla (1-0) L: Bob Apodaca (2-7) S: Tom Walker (1) | Fifth | 23 out |
| » Major-league debuts: Doug Capilla (Cardinals) |
| Monday, September 13 |
| » Defeated Cubs (65-79), 4-3 | Busch Stadium II (33-40) | 63-77 | Won 2 |
| » W: Bob Forsch (6-10) L: Bill Bonham (8-12) | Fifth | 23 out |
| Tuesday, September 14 |
| » Lost to Cubs (66-79), 6-3 | Busch Stadium II (33-41) | 63-78 | |
| » W: Rick Reuschel (13-10) L: Lynn McGlothen (12-14) | Fifth | 24 out |
| Wednesday, September 15 |
| » Defeated Mets (76-68), 7-0 | Shea Stadium (4-3) | 64-78 | |
| » W: John Denny (10-7) L: Mickey Lolich (8-13) | Fifth | 22½ out |
| » Defeated Mets (76-69), 4-1 | Shea Stadium (5-3) | 65-78 | Won 2 |
| » W: Jack Curtis (6-9) L: Nino Espinosa (3-4) | Fifth | 22½ out |
| Thursday, September 16 |
| » Lost to Mets (77-69), 4-1 | Shea Stadium (5-4) | 65-79 | |
| » W: Jerry Koosman (20-8) L: Pete Falcone (12-14) | Fifth | 22½ out |
| Friday, September 17 |
| » Lost to Expos (50-94), 9-5 | Parc Jarry (3-2) | 65-80 | Lost 2 |
| » W: Gerry Hannahs (1-0) L: Eric Rasmussen (5-11) | Fifth | 22½ out |
| Saturday, September 18 |
| » Defeated Expos (50-95), 4-1 | Parc Jarry (4-2) | 66-80 | |
| » W: Bob Forsch (7-10) L: Don Stanhouse (8-11) S: Tom Walker (2) | Fourth | 22 out |
| » Defeated Expos (50-96), 7-4 | Parc Jarry (5-2) | 67-80 | Won 2 |
| » W: Eddie Solomon (1-1) L: Joe Keener (0-1) S: Tom Walker (3) | Fourth | 22 out |
| Sunday, September 19 |
| » Defeated Expos (50-97), 9-7 | Parc Jarry (6-2) | 68-80 | Won 3 |
| » W: Tom Walker (1-1) L: Joe Kerrigan (2-5) S: Bill Greif (6) | Fifth | 21½ out |
| » Lost to Expos (51-97), 1-0 | Parc Jarry (6-3) | 68-81 | |
| » W: Woodie Fryman (13-11) L: Lerrin LaGrow (0-1) | Fifth | 21½ out |
| Tuesday, September 21 |
| » Lost to Phillies (90-59), 5-1 | Veteran's Stadium (2-5) | 68-82 | Lost 2 |
| » W: Tom Underwood (10-5) L: John Denny (10-8) S: Tug McGraw (10) | Fifth | 22½ out |
| Wednesday, September 22 |
| » Lost to Phillies (91-59), 9-4 | Veteran's Stadium (2-6) | 68-83 | Lost 3 |
| » W: Gene Garber (8-3) L: Tom Walker (1-2) | Fifth | 23½ out |
| Thursday, September 23 |
| » Lost to Phillies (92-59), 7-3 | Veteran's Stadium (2-7) | 68-84 | Lost 4 |
| » W: Steve Carlton (19-6) L: Eric Rasmussen (5-12) | Fifth | 24½ out |
| Friday, September 24 |
| » Defeated Pirates (87-67), 10-6 | Busch Stadium II (34-41) | 69-84 | |
| » W: Bob Forsch (8-10) L: John Candelaria (15-7) | Fifth | 24½ out |
| » Lost to Pirates (88-67), 11-1 | Busch Stadium II (34-42) | 69-85 | |
| » W: Jim Rooker (14-8) L: Jack Curtis (6-10) | Fifth | 24½ out |
| Saturday, September 25 |
| » Defeated Pirates (88-68), 3-0 | Busch Stadium II (35-42) | 70-85 | |
| » W: Lynn McGlothen (13-14) L: Jerry Reuss (13-9) | Fifth | 24½ out |
| Sunday, September 26 |
| » Defeated Pirates (88-69), 5-2 | Busch Stadium II (36-42) | 71-85 | Won 2 |
| » W: John Denny (11-8) L: Bruce Kison (14-9) S: Al Hrabosky (13) | Fourth | 25 out |
| Monday, September 27 |
| » Lost to Phillies (97-60), 9-1 | Busch Stadium II (36-43) | 71-86 | |
| » W: Jim Kaat (12-14) L: Pete Falcone (12-15) S: Randy Lerch (1) | Fourth | 26 out |
| » Major-league debuts: Bill Nahorodny (Phillies) |
| Future Cardinal Bo Hart is born in Creswell, OR. |
| Tuesday, September 28 |
| » Defeated Phillies (97-61), 5-3 | Busch Stadium II (37-43) | 72-86 | |
| » W: Eric Rasmussen (6-12) L: Steve Carlton (19-7) | Fourth | 25 out |
| Wednesday, September 29 |
| » Lost to Phillies (98-61), 6-5 | Busch Stadium II (37-44) | 72-87 | |
| » W: Tug McGraw (7-6) L: Jack Curtis (6-11) S: Wayne Twitchell (1) | Fourth | 26 out |
| Saturday, October 2 |
| » Lost to Pirates (90-70), 8-0 | Three Rivers Stadium (2-5) | 72-88 | Lost 2 |
| » W: John Candelaria (16-7) L: Lynn McGlothen (13-15) | Fifth | 27½ out |
| Sunday, October 3 |
| » Lost to Pirates (91-70), 1-0 | Three Rivers Stadium (2-6) | 72-89 | Lost 3 |
| » W: Jim Rooker (15-8) L: John Denny (11-9) | Fifth | 29 out |
| » Lost to Pirates (92-70), 1-0 | Three Rivers Stadium (2-7) | 72-90 | Lost 4 |
| » W: Jerry Reuss (14-9) L: Pete Falcone (12-16) | Fifth | 29 out |
| Friday, November 19 |
| Former Cardinal Frank Kellert dies in Oklahoma City, OK at the age of 53. |
| Wednesday, December 1 |
| Former Cardinal George Earnshaw dies in Little Rock, AR at the age of 77. |
| Friday, December 10 |
| Former Cardinal Vic Keen dies in Salisbury, MD at the age of 78. |
Game information provided by Retrosheet (www.retrosheet.org) |