| Friday, February 14 |
| Future Pirate Damaso Marte is born in Santo Domingo, D.R. |
| Wednesday, March 26 |
| Former Pirate Harley Young dies in Jacksonville, FL at the age of 92. |
| Friday, March 28 |
| Future Pirate Steve Sparks is born in Mobile, AL. |
| Monday, April 7 |
| » Major-league debuts: Jerry Remy (Angels) |
| Tuesday, April 8 |
| » Major-league debuts: Jim Umbarger (Rangers) Lyman Bostock (Twins) |
| Thursday, April 10 |
| » Defeated Cubs (0-1), 8-4 | Wrigley Field (1-0) | 1-0 | |
| » W: Dave Giusti (1-0) L: Ken Frailing (0-1) | First | -- |
| Future Pirate Mike Lincoln is born in Carmichael, CA. |
| Friday, April 11 |
| » Defeated Mets (1-2), 4-3 | Three Rivers Stadium (1-0) | 2-0 | Won 2 |
| » W: Larry Demery (1-0) L: Rick Baldwin (0-1) | First | -- |
| Sunday, April 13 |
| » Defeated Mets (1-3), 5-3 | Three Rivers Stadium (2-0) | 3-0 | Won 3 |
| » W: Bruce Kison (1-0) L: Tom Seaver (1-1) | First | -- |
| Monday, April 14 |
| » Lost to Cubs (4-1), 4-2 | Three Rivers Stadium (2-1) | 3-1 | |
| » W: Rick Reuschel (1-0) L: Bob Moose (0-1) S: Darold Knowles (1) | Second | ½ out |
| Wednesday, April 16 |
| » Lost to Expos (2-5), 5-0 | Three Rivers Stadium (2-2) | 3-2 | Lost 2 |
| » W: Woodie Fryman (1-0) L: Dock Ellis (0-1) | Third | 1½ out |
| Thursday, April 17 |
| » Lost to Expos (3-5), 7-4 | Three Rivers Stadium (2-3) | 3-3 | Lost 3 |
| » W: Dave McNally (2-0) L: Jerry Reuss (0-1) | Third | 2½ out |
| » Major-league debuts: Bombo Rivera (Expos) |
| Friday, April 18 |
| » Lost to Cardinals (6-3), 5-4 | Busch Stadium II (0-1) | 3-4 | Lost 4 |
| » W: Ray Sadecki (1-0) L: Sam McDowell (0-1) | Fourth | 3 out |
| Saturday, April 19 |
| » Defeated Cardinals (6-4), 7-1 | Busch Stadium II (1-1) | 4-4 | |
| » W: Jim Rooker (1-0) L: Bob Forsch (1-2) | Third | 3 out |
| Sunday, April 20 |
| » Defeated Cardinals (6-5), 5-0 | Busch Stadium II (2-1) | 5-4 | Won 2 |
| » W: Ken Brett (1-0) L: John Denny (2-1) S: Dave Giusti (1) | Second | 1½ out |
| Tuesday, April 22 |
| » Lost to Expos (4-7), 4-3 | Parc Jarry (0-1) | 5-5 | |
| » W: Dave McNally (3-0) L: Dock Ellis (0-2) S: Dale Murray (2) | Third | 1½ out |
| Wednesday, April 23 |
| » Lost to Expos (5-7), 5-0 | Parc Jarry (0-2) | 5-6 | Lost 2 |
| » W: Woodie Fryman (2-0) L: Jerry Reuss (0-2) | Fourth | 2½ out |
| Friday, April 25 |
| » Defeated Phillies (6-8), 3-2 | Three Rivers Stadium (3-3) | 6-6 | |
| » W: Bruce Kison (2-0) L: Steve Carlton (0-3) S: Dave Giusti (2) | Third | 3 out |
| Saturday, April 26 |
| » Defeated Phillies (6-9), 7-3 | Three Rivers Stadium (4-3) | 7-6 | Won 2 |
| » W: Jim Rooker (2-0) L: Wayne Twitchell (1-3) | Second | 3 out |
| Sunday, April 27 |
| » Defeated Phillies (6-10), 2-0 | Three Rivers Stadium (5-3) | 8-6 | Won 3 |
| » W: Dock Ellis (1-2) L: Tom Underwood (2-2) | Second | 2½ out |
| Tuesday, April 29 |
| » Lost to Cardinals (7-9), 3-0 | Three Rivers Stadium (5-4) | 8-7 | |
| » W: Lynn McGlothen (2-1) L: Ken Brett (1-1) | Third | 2½ out |
| Wednesday, April 30 |
| » Defeated Cardinals (7-10), 5-0 | Three Rivers Stadium (6-4) | 9-7 | |
| » W: Jerry Reuss (1-2) L: Bob Gibson (0-3) | Second | 2½ out |
| Friday, May 2 |
| » Lost to Phillies (9-10), 9-5 | Veteran's Stadium (0-1) | 9-8 | |
| » W: Wayne Twitchell (2-3) L: Bruce Kison (2-1) S: Tug McGraw (1) | Third | 3 out |
| Saturday, May 3 |
| » Lost to Phillies (10-10), 6-2 | Veteran's Stadium (0-2) | 9-9 | Lost 2 |
| » W: Tom Underwood (3-2) L: Jim Rooker (2-1) S: Gene Garber (2) | Fourth | 4½ out |
| » Lost to Phillies (11-10), 4-3 | Veteran's Stadium (0-3) | 9-10 | Lost 3 |
| » W: Tug McGraw (1-0) L: Ramon Hernandez (0-1) | Fourth | 4½ out |
| Tuesday, May 6 |
| » Defeated Mets (10-10), 2-1 | Shea Stadium (1-0) | 10-10 | |
| » W: Ken Brett (2-1) L: Tom Seaver (3-3) | Second | 3½ out |
| Wednesday, May 7 |
| » Defeated Mets (10-11), 6-1 | Shea Stadium (2-0) | 11-10 | Won 2 |
| » W: Jerry Reuss (2-2) L: Jon Matlack (2-3) | Second | 3½ out |
| Thursday, May 8 |
| » Defeated Mets (10-12), 4-2 | Shea Stadium (3-0) | 12-10 | Won 3 |
| » W: Bruce Kison (3-1) L: Jerry Koosman (2-1) | Second | 3 out |
| Friday, May 9 |
| » Defeated Dodgers (19-11), 11-3 | Three Rivers Stadium (7-4) | 13-10 | Won 4 |
| » W: Dock Ellis (2-2) L: Mike Marshall (2-2) S: Dave Giusti (3) | Second | 3 out |
| Saturday, May 10 |
| » Lost to Dodgers (20-11), 6-2 | Three Rivers Stadium (7-5) | 13-11 | |
| » W: Doug Rau (5-1) L: Jim Rooker (2-2) | Second | 4 out |
| Sunday, May 11 |
| » Lost to Dodgers (21-11), 7-0 | Three Rivers Stadium (7-6) | 13-12 | Lost 2 |
| » W: Don Sutton (7-1) L: Ken Brett (2-2) | Second | 4 out |
| Tuesday, May 13 |
| » Defeated Padres (15-17), 2-0 | Three Rivers Stadium (8-6) | 14-12 | |
| » W: Jerry Reuss (3-2) L: Dan Spillner (2-4) | Second | 4 out |
| Wednesday, May 14 |
| » Defeated Padres (15-18), 5-4 | Three Rivers Stadium (9-6) | 15-12 | Won 2 |
| » W: Sam McDowell (1-1) L: Bill Greif (0-1) | Second | 3 out |
| Thursday, May 15 |
| Former Pirate Johnny Gooch dies in Nashville, TN at the age of 78. |
| Friday, May 16 |
| » Defeated Dodgers (23-13), 3-2 | Dodger Stadium (1-0) | 16-12 | Won 3 |
| » W: Dave Giusti (2-0) L: Don Sutton (7-2) | Second | 2½ out |
| Saturday, May 17 |
| » Lost to Dodgers (24-13), 4-3 | Dodger Stadium (1-1) | 16-13 | |
| » W: Andy Messersmith (6-0) L: Ramon Hernandez (0-2) | Third | 2½ out |
| Sunday, May 18 |
| » Defeated Dodgers (24-14), 7-2 | Dodger Stadium (2-1) | 17-13 | |
| » W: Ken Brett (3-2) L: Burt Hooton (1-4) | Third | 2½ out |
| Monday, May 19 |
| » Lost to Giants (17-19), 6-4 | Candlestick Park (0-1) | 17-14 | |
| » W: Mike Caldwell (1-5) L: Jerry Reuss (3-3) | Third | 2½ out |
| Tuesday, May 20 |
| » Lost to Giants (18-19), 12-4 | Candlestick Park (0-2) | 17-15 | Lost 2 |
| » W: Ed Halicki (1-0) L: Dock Ellis (2-3) | Third | 3½ out |
| Wednesday, May 21 |
| » Lost to Giants (19-19), 2-1 | Candlestick Park (0-3) | 17-16 | Lost 3 |
| » W: Jim Barr (5-3) L: Dave Giusti (2-1) | Third | 3½ out |
| Thursday, May 22 |
| » Defeated Padres (20-20), 4-2 | San Diego/Jack Murphy Stadium (1-0) | 18-16 | |
| » W: Jim Rooker (3-2) L: Dave Freisleben (3-4) S: Dave Giusti (4) | Third | 2½ out |
| Friday, May 23 |
| » Lost to Padres (21-20), 4-3 | San Diego/Jack Murphy Stadium (1-1) | 18-17 | |
| » W: Danny Frisella (1-0) L: Dave Giusti (2-2) | Fourth | 2½ out |
| Saturday, May 24 |
| » Lost to Padres (22-20), 5-0 | San Diego/Jack Murphy Stadium (1-2) | 18-18 | Lost 2 |
| » W: Randy Jones (6-2) L: Jerry Reuss (3-4) | Fourth | 2½ out |
| Sunday, May 25 |
| » Defeated Padres (22-21), 6-5 | San Diego/Jack Murphy Stadium (2-2) | 19-18 | |
| » W: Ramon Hernandez (1-2) L: Danny Frisella (1-1) S: Larry Demery (1) | Second | 1½ out |
| Monday, May 26 |
| » Defeated Astros (18-29), 10-2 | Three Rivers Stadium (10-6) | 20-18 | Won 2 |
| » W: Bruce Kison (4-1) L: J.R. Richard (3-3) | Third | 1½ out |
| Tuesday, May 27 |
| » Defeated Astros (18-30), 6-5 | Three Rivers Stadium (11-6) | 21-18 | Won 3 |
| » W: Larry Demery (2-0) L: Joe Niekro (1-1) | Second | 1½ out |
| Wednesday, May 28 |
| » Defeated Astros (18-31), 3-0 | Three Rivers Stadium (12-6) | 22-18 | Won 4 |
| » W: Ken Brett (4-2) L: Dave Roberts (3-5) | Second | 1½ out |
| Friday, May 30 |
| » Defeated Braves (23-26), 2-1 | Three Rivers Stadium (13-6) | 23-18 | Won 5 |
| » W: Jerry Reuss (4-4) L: Buzz Capra (4-6) | First | -- |
| Saturday, May 31 |
| » Defeated Braves (23-27), 11-4 | Three Rivers Stadium (14-6) | 24-18 | Won 6 |
| » W: Bruce Kison (5-1) L: Roric Harrison (3-4) | First | -- |
| Sunday, June 1 |
| » Lost to Braves (24-27), 5-2 | Three Rivers Stadium (14-7) | 24-19 | |
| » W: Phil Niekro (6-4) L: Jim Rooker (3-3) | Second | 1½ out |
| Tuesday, June 3 |
| » Lost to Reds (30-21), 8-4 | Three Rivers Stadium (14-8) | 24-20 | Lost 2 |
| » W: Gary Nolan (5-3) L: Bob Moose (0-2) | Second | 1½ out |
| Wednesday, June 4 |
| » Defeated Reds (30-22), 2-1 | Three Rivers Stadium (15-8) | 25-20 | |
| » W: Jerry Reuss (5-4) L: Fred Norman (2-2) S: Ramon Hernandez (1) | Second | 1½ out |
| Friday, June 6 |
| » Defeated Giants (25-25), 7-2 | Three Rivers Stadium (16-8) | 26-20 | Won 2 |
| » W: Bruce Kison (6-1) L: Jim Barr (6-4) | First | -- |
| Saturday, June 7 |
| » Defeated Giants (25-26), 7-6 | Three Rivers Stadium (17-8) | 27-20 | Won 3 |
| » W: Ramon Hernandez (2-2) L: Tommy Toms (0-1) S: Dave Giusti (5) | First | -- |
| Sunday, June 8 |
| » Lost to Giants (26-26), 3-1 | Three Rivers Stadium (17-9) | 27-21 | |
| » W: Ed Halicki (2-1) L: John Candelaria (0-1) | First | -- |
| » Lost to Giants (27-26), 4-2 | Three Rivers Stadium (17-10) | 27-22 | Lost 2 |
| » W: Gary Lavelle (4-1) L: Larry Demery (2-1) S: Randy Moffitt (3) | First | -- |
| » Major-league debuts: John Candelaria (Pirates) |
| Monday, June 9 |
| » Defeated Reds (34-23), 9-2 | Riverfront Stadium (1-0) | 28-22 | |
| » W: Jerry Reuss (6-4) L: Fred Norman (2-3) | First | -- |
| Tuesday, June 10 |
| » Defeated Reds (34-24), 9-5 | Riverfront Stadium (2-0) | 29-22 | Won 2 |
| » W: Sam McDowell (2-1) L: Pat Darcy (1-3) S: Ramon Hernandez (2) | First | -- |
| Wednesday, June 11 |
| » Lost to Astros (22-40), 5-1 | Astrodome (0-1) | 29-23 | |
| » W: Larry Dierker (6-6) L: Bruce Kison (6-2) | First | -- |
| Thursday, June 12 |
| » Defeated Astros (22-41), 4-2 | Astrodome (1-1) | 30-23 | |
| » W: Dock Ellis (3-3) L: Dave Roberts (3-8) S: Larry Demery (2) | First | -- |
| Friday, June 13 |
| » Defeated Braves (28-33), 8-3 | Atlanta-Fulton County Stadium (1-0) | 31-23 | Won 2 |
| » W: Jim Rooker (4-3) L: Blue Moon Odom (1-4) | First | -- |
| Saturday, June 14 |
| » Defeated Braves (28-34), 2-1 | Atlanta-Fulton County Stadium (2-0) | 32-23 | Won 3 |
| » W: Jerry Reuss (7-4) L: Mike Thompson (0-1) S: Dave Giusti (6) | First | -- |
| Sunday, June 15 |
| » Defeated Braves (28-35), 8-6 | Atlanta-Fulton County Stadium (3-0) | 33-23 | Won 4 |
| » W: Larry Demery (3-1) L: Elias Sosa (0-5) | First | -- |
| Monday, June 16 |
| » Defeated Cardinals (27-30), 10-4 | Three Rivers Stadium (18-10) | 34-23 | Won 5 |
| » W: Bruce Kison (7-2) L: Ron Bryant (0-1) | First | -- |
| Tuesday, June 17 |
| » Lost to Cardinals (28-30), 7-4 | Three Rivers Stadium (18-11) | 34-24 | |
| » W: Lynn McGlothen (7-5) L: Dock Ellis (3-4) S: Mike Garman (3) | First | -- |
| Former Pirate Sid Gordon dies in New York, NY at the age of 58. |
| Wednesday, June 18 |
| » Defeated Cardinals (28-31), 9-3 | Three Rivers Stadium (19-11) | 35-24 | |
| » W: Jim Rooker (5-3) L: Ron Reed (7-6) | First | -- |
| » Major-league debuts: Mike Barlow (Cardinals) |
| Thursday, June 19 |
| » Defeated Cardinals (28-32), 5-0 | Three Rivers Stadium (20-11) | 36-24 | Won 2 |
| » W: Jerry Reuss (8-4) L: Jack Curtis (4-5) | First | -- |
| Friday, June 20 |
| » Defeated Mets (32-28), 5-1 | Shea Stadium (4-0) | 37-24 | Won 3 |
| » W: John Candelaria (1-1) L: Tom Hall (1-1) | First | -- |
| Saturday, June 21 |
| » Defeated Mets (32-29), 7-3 | Shea Stadium (5-0) | 38-24 | Won 4 |
| » W: Ramon Hernandez (3-2) L: Harry Parker (2-3) | First | -- |
| Sunday, June 22 |
| » Defeated Mets (32-30), 2-0 | Shea Stadium (6-0) | 39-24 | Won 5 |
| » W: Dock Ellis (4-4) L: Randy Tate (2-6) | First | -- |
| Monday, June 23 |
| » Lost to Phillies (37-31), 6-5 | Veteran's Stadium (0-4) | 39-25 | |
| » W: Tom Hilgendorf (1-0) L: Larry Demery (3-2) S: Gene Garber (3) | First | -- |
| Tuesday, June 24 |
| » Lost to Phillies (38-31), 6-3 | Veteran's Stadium (0-5) | 39-26 | Lost 2 |
| » W: Larry Christenson (2-1) L: Jerry Reuss (8-5) S: Tug McGraw (7) | First | -- |
| » Lost to Phillies (39-31), 8-1 | Veteran's Stadium (0-6) | 39-27 | Lost 3 |
| » W: Tom Underwood (8-5) L: Bruce Kison (7-3) | First | -- |
| Wednesday, June 25 |
| » Lost to Phillies (40-31), 7-6 | Veteran's Stadium (0-7) | 39-28 | Lost 4 |
| » W: Ron Schueler (2-1) L: Dave Giusti (2-3) | First | -- |
| Thursday, June 26 |
| » Defeated Cubs (35-36), 5-2 | Three Rivers Stadium (21-11) | 40-28 | |
| » W: John Candelaria (2-1) L: Ken Frailing (2-4) | First | -- |
| Friday, June 27 |
| » Defeated Cubs (35-37), 5-1 | Three Rivers Stadium (22-11) | 41-28 | Won 2 |
| » W: Dock Ellis (5-4) L: Geoff Zahn (2-6) | First | -- |
| » Defeated Cubs (35-38), 5-3 | Three Rivers Stadium (23-11) | 42-28 | Won 3 |
| » W: Ramon Hernandez (4-2) L: Darold Knowles (2-4) S: Dave Giusti (7) | First | -- |
| Saturday, June 28 |
| » Lost to Cubs (36-38), 1-0 | Three Rivers Stadium (23-12) | 42-29 | |
| » W: Bill Bonham (8-5) L: Jim Rooker (5-4) | First | -- |
| Sunday, June 29 |
| » Defeated Cubs (36-39), 4-3 | Three Rivers Stadium (24-12) | 43-29 | |
| » W: Dave Giusti (3-3) L: Rick Reuschel (5-8) | First | -- |
| » Defeated Cubs (36-40), 7-0 | Three Rivers Stadium (25-12) | 44-29 | Won 2 |
| » W: Jerry Reuss (9-5) L: Tom Dettore (1-1) | First | -- |
| Monday, June 30 |
| » Defeated Expos (31-40), 5-3 | Parc Jarry (1-2) | 45-29 | Won 3 |
| » W: Larry Demery (4-2) L: Dennis Blair (5-9) S: Kent Tekulve (1) | First | -- |
| Tuesday, July 1 |
| » Defeated Expos (31-41), 10-4 | Parc Jarry (2-2) | 46-29 | Won 4 |
| » W: John Candelaria (3-1) L: Woodie Fryman (6-5) | First | -- |
| Thursday, July 3 |
| » Defeated Expos (31-42), 5-1 | Parc Jarry (3-2) | 47-29 | Won 5 |
| » W: Dock Ellis (6-4) L: Steve Rogers (5-6) | First | -- |
| Friday, July 4 |
| » Lost to Cubs (38-43), 6-1 | Wrigley Field (1-1) | 47-30 | |
| » W: Steve Stone (6-3) L: Bruce Kison (7-4) | First | -- |
| » Lost to Cubs (39-43), 2-1 | Wrigley Field (1-2) | 47-31 | Lost 2 |
| » W: Darold Knowles (3-4) L: Jerry Reuss (9-6) | First | -- |
| Saturday, July 5 |
| » Defeated Cubs (39-44), 5-4 | Wrigley Field (2-2) | 48-31 | |
| » W: Jim Rooker (6-4) L: Ray Burris (7-6) S: Ramon Hernandez (3) | First | -- |
| Sunday, July 6 |
| » Defeated Cubs (39-45), 18-12 | Wrigley Field (3-2) | 49-31 | Won 2 |
| » W: Ramon Hernandez (5-2) L: Ken Frailing (2-5) | First | -- |
| Monday, July 7 |
| » Defeated Cubs (39-46), 5-0 | Wrigley Field (4-2) | 50-31 | Won 3 |
| » W: Ken Brett (5-2) L: Rick Reuschel (5-10) S: Dave Giusti (8) | First | -- |
| Tuesday, July 8 |
| » Lost to Dodgers (48-38), 3-0 | Three Rivers Stadium (25-13) | 50-32 | |
| » W: Don Sutton (13-8) L: Dock Ellis (6-5) S: Mike Marshall (6) | First | -- |
| Wednesday, July 9 |
| » Defeated Dodgers (48-39), 3-2 | Three Rivers Stadium (26-13) | 51-32 | |
| » W: Bruce Kison (8-4) L: Andy Messersmith (12-6) S: Dave Giusti (9) | First | -- |
| Thursday, July 10 |
| » Defeated Dodgers (48-40), 4-1 | Three Rivers Stadium (27-13) | 52-32 | Won 2 |
| » W: Jerry Reuss (10-6) L: Burt Hooton (6-9) S: Dave Giusti (10) | First | -- |
| Friday, July 11 |
| » Defeated Padres (40-47), 6-2 | Three Rivers Stadium (28-13) | 53-32 | Won 3 |
| » W: Jim Rooker (7-4) L: Rich Folkers (3-7) S: Dave Giusti (11) | First | -- |
| » Defeated Padres (40-48), 5-0 | Three Rivers Stadium (29-13) | 54-32 | Won 4 |
| » W: John Candelaria (4-1) L: Joe McIntosh (7-8) | First | -- |
| Saturday, July 12 |
| » Defeated Padres (40-49), 6-4 | Three Rivers Stadium (30-13) | 55-32 | Won 5 |
| » W: Ramon Hernandez (6-2) L: Randy Jones (11-6) S: Larry Demery (3) | First | -- |
| Sunday, July 13 |
| » Lost to Padres (41-49), 7-5 | Three Rivers Stadium (30-14) | 55-33 | |
| » W: Brent Strom (5-2) L: Dock Ellis (6-6) S: Dan Spillner (1) | First | -- |
| Thursday, July 17 |
| » Defeated Dodgers (49-43), 5-2 | Dodger Stadium (3-1) | 56-33 | |
| » W: Bruce Kison (9-4) L: Andy Messersmith (12-7) S: Dave Giusti (12) | First | -- |
| Friday, July 18 |
| » Lost to Dodgers (50-43), 4-3 | Dodger Stadium (3-2) | 56-34 | |
| » W: Mike Marshall (5-6) L: Larry Demery (4-3) | First | -- |
| Saturday, July 19 |
| » Defeated Dodgers (50-44), 5-3 | Dodger Stadium (4-2) | 57-34 | |
| » W: Dave Giusti (4-3) L: Mike Marshall (5-7) | First | -- |
| Sunday, July 20 |
| » Lost to Giants (44-48), 2-1 | Candlestick Park (0-4) | 57-35 | |
| » W: Ed Halicki (4-6) L: Jim Rooker (7-5) | First | -- |
| » Defeated Giants (44-49), 7-1 | Candlestick Park (1-4) | 58-35 | |
| » W: Ken Brett (6-2) L: Mike Caldwell (5-10) | First | -- |
| Monday, July 21 |
| » Lost to Giants (45-49), 7-2 | Candlestick Park (1-5) | 58-36 | |
| » W: Jim Barr (7-8) L: John Candelaria (4-2) | First | -- |
| Tuesday, July 22 |
| » Lost to Padres (44-53), 1-0 | San Diego/Jack Murphy Stadium (2-3) | 58-37 | Lost 2 |
| » W: Randy Jones (12-6) L: Bruce Kison (9-5) | First | -- |
| Wednesday, July 23 |
| » Defeated Padres (44-54), 8-1 | San Diego/Jack Murphy Stadium (3-3) | 59-37 | |
| » W: Dock Ellis (7-6) L: Dave Freisleben (4-10) | First | -- |
| Friday, July 25 |
| » Defeated Expos (39-54), 6-1 | Three Rivers Stadium (31-14) | 60-37 | Won 2 |
| » W: Jerry Reuss (11-6) L: Don DeMola (3-5) | First | -- |
| Saturday, July 26 |
| » Lost to Expos (40-54), 5-2 | Three Rivers Stadium (31-15) | 60-38 | |
| » W: Steve Rogers (7-7) L: Jim Rooker (7-6) | First | -- |
| Sunday, July 27 |
| » Defeated Expos (40-55), 4-1 | Three Rivers Stadium (32-15) | 61-38 | |
| » W: Ken Brett (7-2) L: Fred Scherman (1-4) S: Larry Demery (4) | First | -- |
| » Defeated Expos (40-56), 5-3 | Three Rivers Stadium (33-15) | 62-38 | Won 2 |
| » W: Dave Giusti (5-3) L: Dan Warthen (4-4) | First | -- |
| Monday, July 28 |
| » Lost to Phillies (58-44), 5-2 | Three Rivers Stadium (33-16) | 62-39 | |
| » W: Larry Christenson (6-2) L: Bruce Kison (9-6) | First | -- |
| Tuesday, July 29 |
| » Lost to Phillies (59-44), 5-1 | Three Rivers Stadium (33-17) | 62-40 | Lost 2 |
| » W: Tom Underwood (11-7) L: Dock Ellis (7-7) | First | -- |
| » Major-league debuts: Willie Randolph (Pirates) |
| Wednesday, July 30 |
| » Defeated Phillies (59-45), 8-1 | Three Rivers Stadium (34-17) | 63-40 | |
| » W: Jerry Reuss (12-6) L: Steve Carlton (10-8) | First | -- |
| Thursday, July 31 |
| » Lost to Mets (54-48), 6-2 | Three Rivers Stadium (34-18) | 63-41 | |
| » W: Jerry Koosman (10-8) L: Jim Rooker (7-7) | First | -- |
| Friday, August 1 |
| » Lost to Mets (55-48), 4-2 | Three Rivers Stadium (34-19) | 63-42 | Lost 2 |
| » W: George Stone (3-2) L: Ken Brett (7-3) S: Bob Apodaca (9) | First | -- |
| » Major-league debuts: Craig Reynolds (Pirates) |
| Saturday, August 2 |
| » Lost to Mets (56-48), 6-0 | Three Rivers Stadium (34-20) | 63-43 | Lost 3 |
| » W: Jon Matlack (13-8) L: Bruce Kison (9-7) | First | -- |
| Sunday, August 3 |
| » Defeated Mets (56-49), 5-4 | Three Rivers Stadium (35-20) | 64-43 | |
| » W: Larry Demery (5-3) L: Bob Apodaca (1-2) | First | -- |
| » Defeated Mets (56-50), 4-3 | Three Rivers Stadium (36-20) | 65-43 | Won 2 |
| » W: John Candelaria (5-2) L: Hank Webb (3-4) | First | -- |
| Monday, August 4 |
| » Lost to Cardinals (56-53), 5-4 | Busch Stadium II (2-2) | 65-44 | |
| » W: Jack Curtis (8-8) L: Jerry Reuss (12-7) S: Al Hrabosky (15) | First | -- |
| Tuesday, August 5 |
| » Defeated Cardinals (56-54), 6-1 | Busch Stadium II (3-2) | 66-44 | |
| » W: Jim Rooker (8-7) L: Eric Rasmussen (1-2) | First | -- |
| Wednesday, August 6 |
| » Lost to Cardinals (57-54), 4-2 | Busch Stadium II (3-3) | 66-45 | |
| » W: John Denny (6-3) L: Ken Brett (7-4) S: Al Hrabosky (16) | First | -- |
| Thursday, August 7 |
| » Lost to Astros (41-75), 6-1 | Astrodome (1-2) | 66-46 | Lost 2 |
| » W: Dave Roberts (7-12) L: Bruce Kison (9-8) | First | -- |
| Friday, August 8 |
| » Lost to Astros (42-75), 5-3 | Astrodome (1-3) | 66-47 | Lost 3 |
| » W: Jim Crawford (2-3) L: Kent Tekulve (0-1) | First | -- |
| Saturday, August 9 |
| » Lost to Astros (43-75), 5-0 | Astrodome (1-4) | 66-48 | Lost 4 |
| » W: Joe Niekro (4-4) L: Jerry Reuss (12-8) | First | -- |
| Sunday, August 10 |
| » Lost to Astros (44-75), 5-3 | Astrodome (1-5) | 66-49 | Lost 5 |
| » W: J.R. Richard (8-7) L: Jim Rooker (8-8) S: Mike Cosgrove (4) | First | -- |
| Monday, August 11 |
| » Defeated Braves (51-66), 8-1 | Atlanta-Fulton County Stadium (4-0) | 67-49 | |
| » W: John Candelaria (6-2) L: Jamie Easterly (1-5) S: Kent Tekulve (2) | First | -- |
| Tuesday, August 12 |
| » Lost to Braves (52-66), 3-2 | Atlanta-Fulton County Stadium (4-1) | 67-50 | |
| » W: Carl Morton (15-12) L: Bruce Kison (9-9) S: Tom House (10) | First | -- |
| Wednesday, August 13 |
| » Lost to Braves (53-66), 4-3 | Atlanta-Fulton County Stadium (4-2) | 67-51 | Lost 2 |
| » W: Tom House (6-4) L: Ken Brett (7-5) | First | -- |
| Thursday, August 14 |
| » Lost to Reds (79-39), 6-1 | Riverfront Stadium (2-1) | 67-52 | Lost 3 |
| » W: Gary Nolan (11-6) L: Jerry Reuss (12-9) | First | -- |
| Friday, August 15 |
| » Lost to Reds (80-39), 8-3 | Riverfront Stadium (2-2) | 67-53 | Lost 4 |
| » W: Fred Norman (8-3) L: Jim Rooker (8-9) | First | -- |
| Saturday, August 16 |
| » Lost to Reds (81-39), 5-3 | Riverfront Stadium (2-3) | 67-54 | Lost 5 |
| » W: Jack Billingham (14-5) L: John Candelaria (6-3) S: Rawly Eastwick (13) | First | -- |
| Sunday, August 17 |
| » Lost to Reds (82-39), 3-1 | Riverfront Stadium (2-4) | 67-55 | Lost 6 |
| » W: Pat Darcy (9-5) L: Bruce Kison (9-10) S: Rawly Eastwick (14) | First | -- |
| Tuesday, August 19 |
| » Defeated Giants (61-63), 4-0 | Three Rivers Stadium (37-20) | 68-55 | |
| » W: Jerry Reuss (13-9) L: Jim Barr (11-10) | First | -- |
| Wednesday, August 20 |
| » Defeated Giants (61-64), 3-1 | Three Rivers Stadium (38-20) | 69-55 | Won 2 |
| » W: Jim Rooker (9-9) L: Ed Halicki (7-10) S: Dave Giusti (13) | First | -- |
| Friday, August 22 |
| » Defeated Reds (83-42), 7-2 | Three Rivers Stadium (39-20) | 70-55 | Won 3 |
| » W: Larry Demery (6-3) L: Jack Billingham (14-6) | First | -- |
| » Defeated Reds (83-43), 4-2 | Three Rivers Stadium (40-20) | 71-55 | Won 4 |
| » W: John Candelaria (7-3) L: Will McEnaney (4-2) S: Dave Giusti (14) | First | -- |
| Saturday, August 23 |
| » Lost to Reds (84-43), 12-7 | Three Rivers Stadium (40-21) | 71-56 | |
| » W: Clay Kirby (9-4) L: Bruce Kison (9-11) S: Rawly Eastwick (16) | First | -- |
| Sunday, August 24 |
| » Defeated Reds (84-44), 5-1 | Three Rivers Stadium (41-21) | 72-56 | |
| » W: Jerry Reuss (14-9) L: Gary Nolan (11-8) | First | -- |
| Monday, August 25 |
| » Defeated Braves (57-74), 4-0 | Three Rivers Stadium (42-21) | 73-56 | Won 2 |
| » W: Jim Rooker (10-9) L: Mike Thompson (0-5) | First | -- |
| Tuesday, August 26 |
| » Defeated Braves (57-75), 8-2 | Three Rivers Stadium (43-21) | 74-56 | Won 3 |
| » W: Larry Demery (7-3) L: Jamie Easterly (1-7) | First | -- |
| Wednesday, August 27 |
| » Lost to Braves (58-75), 6-2 | Three Rivers Stadium (43-22) | 74-57 | |
| » W: Phil Niekro (13-12) L: John Candelaria (7-4) | First | -- |
| Saturday, August 30 |
| » Lost to Astros (52-84), 7-4 | Three Rivers Stadium (43-23) | 74-58 | Lost 2 |
| » W: Larry Dierker (13-13) L: Jerry Reuss (14-10) | First | -- |
| Sunday, August 31 |
| » Defeated Astros (52-85), 9-6 | Three Rivers Stadium (44-23) | 75-58 | |
| » W: Bruce Kison (10-11) L: Jose Sosa (0-3) S: Dave Giusti (15) | First | -- |
| Monday, September 1 |
| » Lost to Mets (72-64), 3-0 | Shea Stadium (6-1) | 75-59 | |
| » W: Tom Seaver (20-7) L: John Candelaria (7-5) | First | -- |
| Tuesday, September 2 |
| » Defeated Mets (72-65), 8-4 | Shea Stadium (7-1) | 76-59 | |
| » W: Kent Tekulve (1-1) L: Jerry Koosman (11-12) S: Dave Giusti (16) | First | -- |
| Wednesday, September 3 |
| » Defeated Mets (72-66), 3-1 | Shea Stadium (8-1) | 77-59 | Won 2 |
| » W: Jerry Reuss (15-10) L: Jon Matlack (16-9) | First | -- |
| Friday, September 5 |
| » Lost to Expos (61-76), 4-3 | Parc Jarry (3-3) | 77-60 | |
| » W: Chuck Taylor (2-2) L: Kent Tekulve (1-2) | First | -- |
| » Defeated Expos (61-77), 5-2 | Parc Jarry (4-3) | 78-60 | |
| » W: Jim Rooker (11-9) L: Steve Renko (5-11) S: Ramon Hernandez (4) | First | -- |
| Saturday, September 6 |
| » Defeated Expos (61-78), 12-5 | Parc Jarry (5-3) | 79-60 | Won 2 |
| » W: Ken Brett (8-5) L: Dale Murray (10-8) | First | -- |
| » Major-league debuts: Omar Moreno (Pirates) |
| Sunday, September 7 |
| » Defeated Expos (61-79), 6-0 | Parc Jarry (6-3) | 80-60 | Won 3 |
| » W: Jerry Reuss (16-10) L: Dennis Blair (8-15) | First | -- |
| Monday, September 8 |
| » Defeated Cubs (67-77), 4-1 | Three Rivers Stadium (45-23) | 81-60 | Won 4 |
| » W: Dock Ellis (8-7) L: Willie Prall (0-1) S: Ramon Hernandez (5) | First | -- |
| Tuesday, September 9 |
| » Lost to Cubs (68-77), 6-5 | Three Rivers Stadium (45-24) | 81-61 | |
| » W: Bill Bonham (13-13) L: Larry Demery (7-4) S: Paul Reuschel (5) | First | -- |
| Wednesday, September 10 |
| » Defeated Mets (73-72), 8-4 | Three Rivers Stadium (46-24) | 82-61 | |
| » W: Jim Rooker (12-9) L: Tom Seaver (21-8) | First | -- |
| Thursday, September 11 |
| » Lost to Mets (74-72), 7-0 | Three Rivers Stadium (46-25) | 82-62 | |
| » W: Jerry Koosman (12-13) L: Jerry Reuss (16-11) | First | -- |
| » Major-league debuts: Odell Jones (Pirates) |
| Friday, September 12 |
| » Defeated Expos (64-82), 6-3 | Three Rivers Stadium (47-25) | 83-62 | |
| » W: Bob Moose (1-2) L: Don Carrithers (3-3) | First | -- |
| Saturday, September 13 |
| » Lost to Expos (65-82), 5-2 | Three Rivers Stadium (47-26) | 83-63 | |
| » W: Dan Warthen (7-6) L: Dock Ellis (8-8) S: Woodie Fryman (2) | First | -- |
| Sunday, September 14 |
| » Defeated Expos (65-83), 4-3 | Three Rivers Stadium (48-26) | 84-63 | |
| » W: Ramon Hernandez (7-2) L: Woodie Fryman (8-11) S: Dave Giusti (17) | First | -- |
| Monday, September 15 |
| » Lost to Cubs (72-78), 6-5 | Wrigley Field (4-3) | 84-64 | |
| » W: Darold Knowles (6-6) L: Dave Giusti (5-4) | First | -- |
| » Defeated Cubs (72-79), 9-1 | Wrigley Field (5-3) | 85-64 | |
| » W: Jim Rooker (13-9) L: Willie Prall (0-2) | First | -- |
| Tuesday, September 16 |
| » Defeated Cubs (72-80), 22-0 | Wrigley Field (6-3) | 86-64 | Won 2 |
| » W: John Candelaria (8-5) L: Rick Reuschel (10-16) | First | -- |
| Wednesday, September 17 |
|