| Tuesday, January 1 |
| Future White Sox Kevin Beirne is born in Houston, TX. |
| Friday, January 18 |
| Former White Sox Pete Appleton dies in Trenton, NJ at the age of 70. |
| Monday, January 28 |
| Future White Sox Magglio Ordonez is born in Caracas, Venezuela. |
| Friday, February 1 |
| Former White Sox Claude Berry dies in Richmond, IN at the age of 94. |
| Tuesday, February 19 |
| Former White Sox Frank Miller dies in Allegan, MI at the age of 88. |
| Wednesday, February 20 |
| Future White Sox Tom Fordham is born in San Diego, CA. |
| Thursday, April 4 |
| » Major-league debuts: Jim Sundberg (Rangers) |
| Friday, April 5 |
| » Lost to Angels (1-0), 8-2 | Comiskey Park I (0-1) | 0-1 | |
| » W: Nolan Ryan (1-0) L: Wilbur Wood (0-1) | Second | 1 out |
| Saturday, April 6 |
| » Lost to Angels (2-0), 3-2 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » W: Dick Selma (1-0) L: Stan Bahnsen (0-1) | Third | 2 out |
| Sunday, April 7 |
| » Tied Angels, 4-4 | Comiskey Park I (0-2) | 0-2 | |
| » Starters: Bill Singer vs Jim Kaat | Fifth | 2 out |
| Tuesday, April 9 |
| » Lost to Twins (2-1), 3-1 | Metropolitan Stadium (0-1) | 0-3 | Lost 3 |
| » W: Bert Blyleven (1-0) L: Wilbur Wood (0-2) S: Bill Campbell (1) | Fifth | 2½ out |
| Wednesday, April 10 |
| » Lost to Twins (3-1), 6-5 | Metropolitan Stadium (0-2) | 0-4 | Lost 4 |
| » W: Ray Corbin (1-0) L: Terry Forster (0-1) S: Bill Campbell (2) | Fifth | 3 out |
| Thursday, April 11 |
| » Tied Twins, 4-4 | Metropolitan Stadium (0-2) | 0-4 | |
| » Starters: Jim Kaat vs Joe Decker | Sixth | 3½ out |
| Friday, April 12 |
| » Lost to Angels (5-1), 15-1 | Anaheim Stadium (0-1) | 0-5 | Lost 5 |
| » W: Nolan Ryan (2-1) L: Terry Forster (0-2) | Sixth | 4½ out |
| Saturday, April 13 |
| » Defeated Angels (5-2), 5-4 | Anaheim Stadium (1-1) | 1-5 | |
| » W: Wilbur Wood (1-2) L: Rudy May (0-1) | Fifth | 3½ out |
| Sunday, April 14 |
| » Lost to Angels (6-2), 6-3 | Anaheim Stadium (1-2) | 1-6 | |
| » W: Frank Tanana (2-0) L: Stan Bahnsen (0-2) S: Dick Selma (1) | Sixth | 4½ out |
| Monday, April 15 |
| » Lost to Athletics (5-4), 4-3 | Oakland-Alameda County Stadium (0-1) | 1-7 | Lost 2 |
| » W: Rollie Fingers (2-0) L: Terry Forster (0-3) | Sixth | 5½ out |
| Tuesday, April 16 |
| » Lost to Athletics (6-4), 4-3 | Oakland-Alameda County Stadium (0-2) | 1-8 | Lost 3 |
| » W: Paul Lindblad (1-0) L: Wilbur Wood (1-3) S: Rollie Fingers (1) | Sixth | 5½ out |
| Wednesday, April 17 |
| » Defeated Athletics (6-5), 5-3 | Oakland-Alameda County Stadium (1-2) | 2-8 | |
| » W: Stan Bahnsen (1-2) L: Vida Blue (0-2) | Fifth | 5½ out |
| Friday, April 19 |
| » Defeated Royals (3-6), 5-4 | Comiskey Park I (1-2) | 3-8 | Won 2 |
| » W: Jim Kaat (1-0) L: Bruce Dal Canton (1-1) S: Terry Forster (1) | Fifth | 4 out |
| Saturday, April 20 |
| » Lost to Royals (4-6), 7-3 | Comiskey Park I (1-3) | 3-9 | |
| » W: Paul Splittorff (1-1) L: Wilbur Wood (1-4) | Fifth | 4½ out |
| Sunday, April 21 |
| » Defeated Royals (4-7), 11-7 | Comiskey Park I (2-3) | 4-9 | |
| » W: Terry Forster (1-3) L: Steve Busby (2-2) | Fifth | 4 out |
| Tuesday, April 23 |
| » Defeated Brewers (7-5), 3-2 | Comiskey Park I (3-3) | 5-9 | Won 2 |
| » W: Jim Kaat (2-0) L: Jim Slaton (1-2) S: Cy Acosta (1) | Fifth | 3 out |
| Wednesday, April 24 |
| » Defeated Brewers (7-6), 7-2 | Comiskey Park I (4-3) | 6-9 | Won 3 |
| » W: Wilbur Wood (2-4) L: Clyde Wright (3-1) S: Terry Forster (2) | Fifth | 3 out |
| Friday, April 26 |
| » Defeated Tigers (6-10), 8-2 | Comiskey Park I (5-3) | 7-9 | Won 4 |
| » W: Stan Bahnsen (2-2) L: Mickey Lolich (0-4) | Fifth | 2½ out |
| Saturday, April 27 |
| » Lost to Tigers (7-10), 8-3 | Comiskey Park I (5-4) | 7-10 | |
| » W: Lerrin LaGrow (1-2) L: Jim Kaat (2-1) S: John Hiller (2) | Fifth | 3½ out |
| Sunday, April 28 |
| » Lost to Tigers (8-10), 6-4 | Comiskey Park I (5-5) | 7-11 | Lost 2 |
| » W: Joe Coleman (4-1) L: Wilbur Wood (2-5) S: John Hiller (3) | Sixth | 4 out |
| Monday, April 29 |
| » Major-league debuts: Jim Todd (Cubs) |
| Tuesday, April 30 |
| » Defeated Orioles (11-8), 2-1 | Comiskey Park I (6-5) | 8-11 | |
| » W: Stan Bahnsen (3-2) L: Jim Palmer (2-1) | Fifth | 4 out |
| Wednesday, May 1 |
| » Defeated Orioles (11-9), 2-0 | Comiskey Park I (7-5) | 9-11 | Won 2 |
| » W: Jim Kaat (3-1) L: Dave McNally (2-2) S: Terry Forster (3) | Fourth | 3 out |
| Friday, May 3 |
| » Defeated Brewers (10-9), 10-3 | County Stadium (1-0) | 10-11 | Won 3 |
| » W: Wilbur Wood (3-5) L: Clyde Wright (3-3) | Fourth | 2½ out |
| Saturday, May 4 |
| » Defeated Brewers (10-10), 4-2 | County Stadium (2-0) | 11-11 | Won 4 |
| » W: Stan Bahnsen (4-2) L: Jim Colborn (1-2) S: Terry Forster (4) | Third | 2½ out |
| Sunday, May 5 |
| » Defeated Brewers (10-11), 4-3 | County Stadium (3-0) | 12-11 | Won 5 |
| » W: Jim Kaat (4-1) L: Jim Slaton (3-3) S: Terry Forster (5) | Third | 2 out |
| Monday, May 6 |
| » Lost to Tigers (13-12), 5-4 | Tiger Stadium (0-1) | 12-12 | |
| » W: John Hiller (4-0) L: Cy Acosta (0-1) | Third | 2 out |
| Tuesday, May 7 |
| » Defeated Tigers (13-13), 1-0 | Tiger Stadium (1-1) | 13-12 | |
| » W: Wilbur Wood (4-5) L: Lerrin LaGrow (2-3) | Third | 1 out |
| Friday, May 10 |
| » Defeated Rangers (15-15), 8-7 | Arlington Stadium (1-0) | 14-12 | Won 2 |
| » W: Terry Forster (2-3) L: Steve Foucault (1-2) | First | -- |
| Saturday, May 11 |
| » Lost to Rangers (16-15), 3-2 | Arlington Stadium (1-1) | 14-13 | |
| » W: David Clyde (2-0) L: Jim Kaat (4-2) | First | -- |
| Sunday, May 12 |
| » Defeated Rangers (16-16), 5-4 | Arlington Stadium (2-1) | 15-13 | |
| » W: Wilbur Wood (5-5) L: Fergie Jenkins (6-3) S: Cy Acosta (2) | First | -- |
| Monday, May 13 |
| » Lost to Twins (13-15), 7-5 | Comiskey Park I (7-6) | 15-14 | |
| » W: Dave Goltz (1-0) L: Bill Moran (0-1) S: Bill Campbell (7) | Second | 1½ out |
| Wednesday, May 15 |
| » Defeated Twins (13-16), 1-0 | Comiskey Park I (8-6) | 16-14 | |
| » W: Stan Bahnsen (5-2) L: Bert Blyleven (3-5) | First | -- |
| Thursday, May 16 |
| » Defeated Athletics (18-17), 4-3 | Comiskey Park I (9-6) | 17-14 | Won 2 |
| » W: Wilbur Wood (6-5) L: Ken Holtzman (3-5) S: Terry Forster (6) | First | -- |
| Friday, May 17 |
| » Lost to Athletics (19-17), 10-4 | Comiskey Park I (9-7) | 17-15 | |
| » W: Dave Hamilton (2-0) L: Jim Kaat (4-3) | First | -- |
| Saturday, May 18 |
| » Defeated Athletics (19-18), 3-2 | Comiskey Park I (10-7) | 18-15 | |
| » W: Bill Moran (1-1) L: Vida Blue (2-5) S: Terry Forster (7) | First | -- |
| » Major-league debuts: Lamar Johnson (White Sox) |
| Sunday, May 19 |
| » Lost to Athletics (20-18), 8-3 | Comiskey Park I (10-8) | 18-16 | |
| » W: Catfish Hunter (7-3) L: Stan Bahnsen (5-3) | First | -- |
| Wednesday, May 22 |
| » Defeated Rangers (19-20), 6-2 | Comiskey Park I (11-8) | 19-16 | |
| » W: Wilbur Wood (7-5) L: Jim Bibby (5-7) | Second | 2½ out |
| » Lost to Rangers (20-20), 8-2 | Comiskey Park I (11-9) | 19-17 | |
| » W: Fergie Jenkins (7-4) L: Jim Kaat (4-4) | Second | 2½ out |
| Thursday, May 23 |
| » Defeated Rangers (20-21), 9-6 | Comiskey Park I (12-9) | 20-17 | |
| » W: Skip Pitlock (1-0) L: Lloyd Allen (0-1) S: Terry Forster (8) | Second | 2 out |
| Friday, May 24 |
| » Lost to Royals (20-21), 4-2 | Royals Stadium (0-1) | 20-18 | |
| » W: Paul Splittorff (5-4) L: Stan Bahnsen (5-4) | Second | 2 out |
| Saturday, May 25 |
| » Lost to Royals (21-21), 4-3 | Royals Stadium (0-2) | 20-19 | Lost 2 |
| » W: Doug Bird (2-1) L: Wilbur Wood (7-6) | Second | 2 out |
| Sunday, May 26 |
| » Lost to Royals (22-21), 4-1 | Royals Stadium (0-3) | 20-20 | Lost 3 |
| » W: Al Fitzmorris (4-2) L: Jim Kaat (4-5) | Third | 2 out |
| Monday, May 27 |
| » Defeated Yankees (22-26), 5-3 | Shea Stadium (1-0) | 21-20 | |
| » W: Skip Pitlock (2-0) L: Doc Medich (6-4) S: Terry Forster (9) | Third | 2 out |
| Tuesday, May 28 |
| » Lost to Yankees (23-26), 3-2 | Shea Stadium (1-1) | 21-21 | |
| » W: Sparky Lyle (2-0) L: Terry Forster (2-4) | Third | 2 out |
| Friday, May 31 |
| » Defeated Red Sox (25-22), 3-2 | Fenway Park (1-0) | 22-21 | |
| » W: Wilbur Wood (8-6) L: Bill Lee (6-5) S: Terry Forster (10) | Third | 2½ out |
| Saturday, June 1 |
| » Lost to Red Sox (26-22), 8-0 | Fenway Park (1-1) | 22-22 | |
| » W: Luis Tiant (6-5) L: Stan Bahnsen (5-5) | Fourth | 3½ out |
| Sunday, June 2 |
| » Lost to Red Sox (27-22), 9-7 | Fenway Park (1-2) | 22-23 | Lost 2 |
| » W: Reggie Cleveland (4-5) L: Jim Kaat (4-6) | Fourth | 4½ out |
| Tuesday, June 4 |
| » Defeated Yankees (25-28), 9-2 | Comiskey Park I (13-9) | 23-23 | |
| » W: Wilbur Wood (9-6) L: Pat Dobson (3-8) | Third | 4 out |
| Wednesday, June 5 |
| » Defeated Yankees (25-29), 7-6 | Comiskey Park I (14-9) | 24-23 | Won 2 |
| » W: Terry Forster (3-4) L: Cecil Upshaw (0-3) | Second | 4 out |
| Thursday, June 6 |
| » Lost to Yankees (26-29), 5-1 | Comiskey Park I (14-10) | 24-24 | |
| » W: Doc Medich (7-4) L: Stan Bahnsen (5-6) | Second | 4½ out |
| Friday, June 7 |
| » Defeated Red Sox (29-24), 8-6 | Comiskey Park I (15-10) | 25-24 | |
| » W: Jim Kaat (5-6) L: Roger Moret (0-1) S: Cy Acosta (3) | Second | 3½ out |
| » Major-league debuts: Joe Henderson (White Sox) |
| Saturday, June 8 |
| » Defeated Red Sox (29-25), 13-6 | Comiskey Park I (16-10) | 26-24 | Won 2 |
| » W: Wilbur Wood (10-6) L: Bob Veale (0-1) | Second | 2½ out |
| Sunday, June 9 |
| » Lost to Red Sox (30-25), 10-6 | Comiskey Park I (16-11) | 26-25 | |
| » W: Bill Lee (7-5) L: Skip Pitlock (2-1) | Second | 3½ out |
| Former White Sox Pat Caraway dies in ElPaso, TX at the age of 69. |
| Tuesday, June 11 |
| » Lost to Indians (28-26), 6-0 | Comiskey Park I (16-12) | 26-26 | Lost 2 |
| » W: Jim Perry (5-5) L: Stan Bahnsen (5-7) | Third | 3 out |
| Wednesday, June 12 |
| » Lost to Indians (29-26), 10-1 | Comiskey Park I (16-13) | 26-27 | Lost 3 |
| » W: Gaylord Perry (11-1) L: Wilbur Wood (10-7) | Fourth | 3 out |
| Friday, June 14 |
| » Lost to Orioles (29-29), 2-1 | Memorial Stadium (0-1) | 26-28 | Lost 4 |
| » W: Ross Grimsley (6-7) L: Terry Forster (3-5) | Fourth | 3 out |
| Saturday, June 15 |
| » Lost to Orioles (30-29), 4-3 | Memorial Stadium (0-2) | 26-29 | Lost 5 |
| » W: Dave McNally (5-5) L: Cy Acosta (0-2) | Fourth | 4 out |
| Sunday, June 16 |
| » Defeated Orioles (30-30), 9-1 | Memorial Stadium (1-2) | 27-29 | |
| » W: Wilbur Wood (11-7) L: Jim Palmer (3-8) | Fourth | 3 out |
| Monday, June 17 |
| » Lost to Indians (32-28), 4-3 | Cleveland Stadium (0-1) | 27-30 | |
| » W: Gaylord Perry (12-1) L: Cy Acosta (0-3) | Fourth | 4 out |
| Tuesday, June 18 |
| » Defeated Indians (32-29), 7-3 | Cleveland Stadium (1-1) | 28-30 | |
| » W: Jim Kaat (6-6) L: Bob Johnson (3-4) | Fourth | 3 out |
| Wednesday, June 19 |
| » Defeated Indians (32-30), 15-4 | Cleveland Stadium (2-1) | 29-30 | Won 2 |
| » W: Stan Bahnsen (6-7) L: Steve Arlin (1-8) S: Skip Pitlock (1) | Fourth | 3 out |
| Thursday, June 20 |
| » Lost to Twins (26-36), 3-2 | Metropolitan Stadium (0-3) | 29-31 | |
| » W: Ray Corbin (5-0) L: Wilbur Wood (11-8) S: Bill Campbell (10) | Fourth | 3 out |
| Friday, June 21 |
| » Defeated Twins (26-37), 11-7 | Metropolitan Stadium (1-3) | 30-31 | |
| » W: Joe Henderson (1-0) L: Dave Goltz (1-3) | Fourth | 3 out |
| Saturday, June 22 |
| » Defeated Twins (26-38), 3-1 | Metropolitan Stadium (2-3) | 31-31 | Won 2 |
| » W: Jim Kaat (7-6) L: Vic Albury (2-7) | Third | 3 out |
| Former White Sox Homer Blankenship dies in Longview, TX at the age of 72. |
| Sunday, June 23 |
| » Defeated Twins (26-39), 2-1 | Metropolitan Stadium (3-3) | 32-31 | Won 3 |
| » W: Stan Bahnsen (7-7) L: Joe Decker (7-6) | Third | 2½ out |
| » Lost to Twins (27-39), 4-3 | Metropolitan Stadium (3-4) | 32-32 | |
| » W: Bill Butler (2-2) L: Skip Pitlock (2-2) | Third | 2½ out |
| Monday, June 24 |
| » Defeated Royals (33-34), 3-1 | Royals Stadium (1-3) | 33-32 | |
| » W: Wilbur Wood (12-8) L: Steve Busby (9-7) S: Terry Forster (11) | Second | 2½ out |
| Tuesday, June 25 |
| » Defeated Royals (33-35), 10-9 | Royals Stadium (2-3) | 34-32 | Won 2 |
| » W: Terry Forster (4-5) L: Joe Hoerner (1-3) | Second | 2½ out |
| Wednesday, June 26 |
| » Lost to Royals (34-35), 2-1 | Royals Stadium (2-4) | 34-33 | |
| » W: Paul Splittorff (8-7) L: Rich Gossage (0-1) | Second | 3½ out |
| Thursday, June 27 |
| » Lost to Twins (30-40), 6-3 | Comiskey Park I (16-14) | 34-34 | Lost 2 |
| » W: Joe Decker (8-6) L: Stan Bahnsen (7-8) | Second | 3½ out |
| Friday, June 28 |
| » Lost to Twins (31-40), 10-3 | Comiskey Park I (16-15) | 34-35 | Lost 3 |
| » W: Bill Butler (3-2) L: Wilbur Wood (12-9) S: Dave Goltz (1) | Third | 4½ out |
| Saturday, June 29 |
| » Defeated Twins (31-41), 4-3 | Comiskey Park I (17-15) | 35-35 | |
| » W: Terry Forster (5-5) L: Bert Blyleven (6-10) | Second | 3½ out |
| Sunday, June 30 |
| » Defeated Twins (31-42), 8-3 | Comiskey Park I (18-15) | 36-35 | Won 2 |
| » W: Jim Kaat (8-6) L: Ray Corbin (5-1) | Third | 3 out |
| » Lost to Twins (32-42), 6-3 | Comiskey Park I (18-16) | 36-36 | |
| » W: Vic Albury (4-7) L: Rich Gossage (0-2) S: Bill Campbell (11) | Third | 3 out |
| Former White Sox Mule Haas dies in New Orleans, LA at the age of 71. |
| Monday, July 1 |
| » Lost to Royals (38-36), 9-0 | Comiskey Park I (18-17) | 36-37 | Lost 2 |
| » W: Bruce Dal Canton (4-4) L: Stan Bahnsen (7-9) | Fourth | 4 out |
| Tuesday, July 2 |
| » Defeated Royals (38-37), 4-1 | Comiskey Park I (19-17) | 37-37 | |
| » W: Wilbur Wood (13-9) L: Lindy McDaniel (1-3) | Third | 4 out |
| Wednesday, July 3 |
| » Lost to Royals (39-37), 5-3 | Comiskey Park I (19-18) | 37-38 | |
| » W: Paul Splittorff (9-7) L: Bill Moran (1-2) S: Doug Bird (4) | Fourth | 5 out |
| Thursday, July 4 |
| » Defeated Royals (39-38), 11-3 | Comiskey Park I (20-18) | 38-38 | |
| » W: Jim Kaat (9-6) L: Steve Busby (10-8) S: Terry Forster (12) | Third | 5 out |
| Friday, July 5 |
| » Lost to Tigers (42-37), 9-6 | Tiger Stadium (1-2) | 38-39 | |
| » W: Joe Coleman (7-9) L: Stan Bahnsen (7-10) | Fourth | 6½ out |
| » Lost to Tigers (43-37), 7-4 | Tiger Stadium (1-3) | 38-40 | Lost 2 |
| » W: Lerrin LaGrow (7-7) L: Bill Moran (1-3) | Fourth | 6½ out |
| Saturday, July 6 |
| » Defeated Tigers (43-38), 9-8 | Tiger Stadium (2-3) | 39-40 | |
| » W: Wilbur Wood (14-9) L: Luke Walker (4-1) S: Terry Forster (13) | Third | 5½ out |
| Sunday, July 7 |
| » Defeated Tigers (43-39), 3-1 | Tiger Stadium (3-3) | 40-40 | Won 2 |
| » W: Bart Johnson (1-0) L: Mickey Lolich (10-9) | Third | 4½ out |
| Monday, July 8 |
| » Lost to Brewers (41-41), 6-5 | County Stadium (3-1) | 40-41 | |
| » W: Bill Travers (2-0) L: Stan Bahnsen (7-11) | Third | 5½ out |
| Tuesday, July 9 |
| » Lost to Brewers (42-41), 6-5 | County Stadium (3-2) | 40-42 | Lost 2 |
| » W: Eduardo Rodriguez (6-2) L: Rich Gossage (0-3) | Third | 6½ out |
| Former White Sox Leo Mangum dies in Lima, OH at the age of 79. |
| Wednesday, July 10 |
| » Lost to Brewers (43-41), 6-1 | County Stadium (3-3) | 40-43 | Lost 3 |
| » W: Bill Champion (4-1) L: Wilbur Wood (14-10) | Third | 7 out |
| Thursday, July 11 |
| » Defeated Orioles (46-38), 4-3 | Comiskey Park I (21-18) | 41-43 | |
| » W: Bart Johnson (2-0) L: Bob Reynolds (4-3) | Third | 6½ out |
| Friday, July 12 |
| » Defeated Orioles (46-39), 4-3 | Comiskey Park I (22-18) | 42-43 | Won 2 |
| » W: Rich Gossage (1-3) L: Doyle Alexander (4-5) | Third | 5½ out |
| Saturday, July 13 |
| » Lost to Orioles (47-39), 2-1 | Comiskey Park I (22-19) | 42-44 | |
| » W: Mike Cuellar (12-5) L: Wilbur Wood (14-11) S: Grant Jackson (6) | Third | 5½ out |
| Sunday, July 14 |
| » Defeated Orioles (47-40), 3-1 | Comiskey Park I (23-19) | 43-44 | |
| » W: Stan Bahnsen (8-11) L: Ross Grimsley (11-8) S: Rich Gossage (1) | Third | 6 out |
| Monday, July 15 |
| » Defeated Tigers (44-45), 3-2 | Comiskey Park I (24-19) | 44-44 | Won 2 |
| » W: Rich Gossage (2-3) L: Lerrin LaGrow (7-8) | Third | 6 out |
| Tuesday, July 16 |
| » Defeated Tigers (44-46), 6-0 | Comiskey Park I (25-19) | 45-44 | Won 3 |
| » W: Jim Kaat (10-6) L: Mickey Lolich (10-11) | Third | 6 out |
| Wednesday, July 17 |
| » Defeated Tigers (44-47), 7-1 | Comiskey Park I (26-19) | 46-44 | Won 4 |
| » W: Wilbur Wood (15-11) L: Woodie Fryman (4-6) | Second | 6 out |
| Friday, July 19 |
| » Defeated Brewers (46-46), 7-3 | Comiskey Park I (27-19) | 47-44 | Won 5 |
| » W: Bart Johnson (3-0) L: Ed Sprague (7-2) S: Terry Forster (14) | Second | 5½ out |
| Saturday, July 20 |
| » Defeated Brewers (46-47), 3-2 | Comiskey Park I (28-19) | 48-44 | Won 6 |
| » W: Wilbur Wood (16-11) L: Clyde Wright (8-12) | Second | 4½ out |
| Sunday, July 21 |
| » Defeated Brewers (46-48), 6-2 | Comiskey Park I (29-19) | 49-44 | Won 7 |
| » W: Jim Kaat (11-6) L: Jim Colborn (6-7) S: Terry Forster (15) | Second | 5 out |
| » Lost to Brewers (47-48), 5-3 | Comiskey Park I (29-20) | 49-45 | |
| » W: Tom Murphy (3-4) L: Terry Forster (5-6) | Second | 5 out |
| Thursday, July 25 |
| » Lost to Rangers (48-50), 4-1 | Arlington Stadium (2-2) | 49-46 | Lost 2 |
| » W: Fergie Jenkins (13-9) L: Wilbur Wood (16-12) | Second | 6 out |
| Friday, July 26 |
| » Lost to Rangers (49-50), 10-6 | Arlington Stadium (2-3) | 49-47 | Lost 3 |
| » W: Jim Bibby (14-12) L: Jim Kaat (11-7) | Second | 7 out |
| Saturday, July 27 |
| » Defeated Rangers (49-51), 9-5 | Arlington Stadium (3-3) | 50-47 | |
| » W: Skip Pitlock (3-2) L: Steve Hargan (9-6) | Second | 6 out |
| Sunday, July 28 |
| » Lost to Athletics (58-42), 7-2 | Oakland-Alameda County Stadium (1-3) | 50-48 | |
| » W: Ken Holtzman (11-11) L: Stan Bahnsen (8-12) | Third | 8 out |
| » Lost to Athletics (59-42), 3-2 | Oakland-Alameda County Stadium (1-4) | 50-49 | Lost 2 |
| » W: Paul Lindblad (3-2) L: Lloyd Allen (0-2) S: Rollie Fingers (11) | Third | 8 out |
| Monday, July 29 |
| » Lost to Athletics (60-42), 11-9 | Oakland-Alameda County Stadium (1-5) | 50-50 | Lost 3 |
| » W: Paul Lindblad (4-2) L: Terry Forster (5-7) | Third | 9 out |
| Tuesday, July 30 |
| » Defeated Angels (40-64), 3-2 | Anaheim Stadium (2-2) | 51-50 | |
| » W: Jim Kaat (12-7) L: Nolan Ryan (13-11) S: Terry Forster (16) | Second | 9 out |
| Wednesday, July 31 |
| » Lost to Angels (41-64), 14-4 | Anaheim Stadium (2-3) | 51-51 | |
| » W: Luis Quintana (1-1) L: Skip Pitlock (3-3) | Third | 9 out |
| » Major-league debuts: Jim Otten (White Sox) |
| Thursday, August 1 |
| » Defeated Athletics (61-44), 7-3 | Comiskey Park I (30-20) | 52-51 | |
| » W: Stan Bahnsen (9-12) L: Ken Holtzman (11-12) | Third | 8 out |
| Friday, August 2 |
| » Lost to Athletics (62-44), 3-2 | Comiskey Park I (30-21) | 52-52 | |
| » W: Vida Blue (13-9) L: Wilbur Wood (16-13) | Third | 9 out |
| Saturday, August 3 |
| » Lost to Rangers (54-53), 12-5 | Comiskey Park I (30-22) | 52-53 | Lost 2 |
| » W: Jim Bibby (15-13) L: Jim Kaat (12-8) | Fourth | 9½ out |
| Sunday, August 4 |
| » Defeated Rangers (54-54), 6-3 | Comiskey Park I (31-22) | 53-53 | |
| » W: Bart Johnson (4-0) L: Steve Foucault (4-5) | Third | 8½ out |
| » Defeated Rangers (54-55), 13-10 | Comiskey Park I (32-22) | 54-53 | Won 2 |
| » W: Terry Forster (6-7) L: Steve Foucault (4-6) | Third | 8½ out |
| Monday, August 5 |
| » Lost to Rangers (55-55), 13-8 | Comiskey Park I (32-23) | 54-54 | |
| » W: Don Stanhouse (1-1) L: Stan Bahnsen (9-13) | Third | 9 out |
| Tuesday, August 6 |
| » Defeated Angels (43-68), 12-2 | Comiskey Park I (33-23) | 55-54 | |
| » W: Wilbur Wood (17-13) L: Andy Hassler (2-6) | Fourth | 8 out |
| Wednesday, August 7 |
| » Defeated Angels (43-69), 2-1 | Comiskey Park I (34-23) | 56-54 | Won 2 |
| » W: Jim Kaat (13-8) L: Nolan Ryan (14-12) | Third | 8 out |
| Thursday, August 8 |
| » Lost to Angels (44-69), 6-4 | Comiskey Park I (34-24) | 56-55 | |
| » W: Luis Quintana (2-1) L: Rich Gossage (2-4) S: Andy Hassler (1) | Third | 9 out |
| » Major-league debuts: Jack Kucek (White Sox) |
| Former White Sox Howie Pollet dies in Houston, TX at the age of 54. |
| Friday, August 9 |
| » Defeated Indians (57-52), 5-3 | Cleveland Stadium (3-1) | 57-55 | |
| » W: Stan Bahnsen (10-13) L: Gaylord Perry (15-7) S: Terry Forster (17) | Third | 8 out |
| Saturday, August 10 |
| » Defeated Indians (57-53), 5-1 | Cleveland Stadium (4-1) | 58-55 | Won 2 |
| » W: Wilbur Wood (18-13) L: Dick Bosman (5-1) | Third | 8 out |
| Sunday, August 11 |
| » Lost to Indians (58-53), 3-2 | Cleveland Stadium (4-2) | 58-56 | |
| » W: Jim Perry (12-8) L: Jim Kaat (13-9) S: Tom Buskey (12) | Fourth | 8 out |
| Tuesday, August 13 |
| » Lost to Orioles (58-57), 8-2 | Memorial Stadium (1-3) | 58-57 | Lost 2 |
| » W: Jim Palmer (4-8) L: Bart Johnson (4-1) S: Grant Jackson (9) | Third | 9½ out |
| Wednesday, August 14 |
| » Defeated Orioles (58-58), 5-4 | Memorial Stadium (2-3) | 59-57 | |
| » W: Terry Forster (7-7) L: Doyle Alexander (5-9) | Third | 8½ out |
| Thursday, August 15 |
| » Lost to Orioles (59-58), 2-1 | Memorial Stadium (2-4) | 59-58 | |
| » W: Mike Cuellar (14-9) L: Jim Kaat (13-10) | Third | 9 out |
| Friday, August 16 |
| » Lost to Yankees (58-59), 9-8 | Shea Stadium (1-2) | 59-59 | Lost 2 |
| » W: Sparky Lyle (7-3) L: Terry Forster (7-8) | Third | 8½ out |
| » Defeated Yankees (58-60), 4-2 | Shea Stadium (2-2) | 60-59 | |
| » W: Stan Bahnsen (11-13) L: Dick Tidrow (9-10) | Third | 8½ out |
| Saturday, August 17 |
| » Lost to Yankees (59-60), 2-1 | Shea Stadium (2-3) | 60-60 | |
| » W: Doc Medich (14-11) L: Bart Johnson (4-2) | Third | 8½ out |
| Future White Sox Jeff Liefer is born in Fontana, CA. |
| Sunday, August 18 |
| » Lost to Yankees (60-60), 9-4 | Shea Stadium (2-4) | 60-61 | Lost 2 |
| » W: Mike Wallace (6-0) L: Wilbur Wood (18-14) S: Sparky Lyle (12) | Fourth | 9½ out |
| » Major-league debuts: Francisco Barrios (White Sox) |
| Monday, August 19 |
| » Lost to Red Sox (67-54), 6-1 | Fenway Park (1-3) | 60-62 | Lost 3 |
| » W: Bill Lee (14-11) L: Jim Kaat (13-11) S: Diego Segui (8) | Fourth | 9½ out |
| » Major-league debuts: Jim Rice (Red Sox) |
| Tuesday, August 20 |
| » Lost to Red Sox (68-54), 8-3 | Fenway Park (1-4) | 60-63 | Lost 4 |
| » W: Dick Drago (6-7) L: Stan Bahnsen (11-14) | Fourth | 10½ out |
| Wednesday, August 21 |
| » Lost to Red Sox (69-54), 4-0 | Fenway Park (1-5) | 60-64 | Lost 5 |
| » W: Roger Moret (7-5) L: Wilbur Wood (18-15) | Fourth | 10½ out |
| Friday, August 23 |
| » Defeated Indians (61-59), 2-1 | Comiskey Park I (35-24) | 61-64 | |
| » W: Jim Kaat (14-11) L: Fritz Peterson (8-9) | Fourth | 9½ out |
| Saturday, August 24 |
| » Defeated Indians (61-60), 3-0 | Comiskey Park I (36-24) | 62-64 | Won 2 |
| » W: Bart Johnson (5-2) L: Gaylord Perry (16-9) | Fourth | 9½ out |
| Sunday, August 25 |
| » Defeated Indians (61-61), 8-5 | Comiskey Park I (37-24) | 63-64 | Won 3 |
| » W: Wilbur Wood (19-15) L: Dick Bosman (5-3) | Fourth | 9 out |
| » Defeated Indians (61-62), 8-5 | Comiskey Park I (38-24) | 64-64 | Won 4 |
| » W: Rich Gossage (3-4) L: Steve Arlin (3-12) S: Terry Forster (18) | Fourth | 9 out |
| Tuesday, August 27 |
| » Lost to Red Sox (71-56), 6-1 | Comiskey Park I (38-25) | 64-65 | |
| » W: Reggie Cleveland (9-12) L: Jim Kaat (14-12) | Fourth | 9½ out |
| Wednesday, August 28 |
| » Defeated Red Sox (71-57), 3-0 | Comiskey Park I (39-25) | 65-65 | |
| » W: Bart Johnson (6-2) L: Luis Tiant (20-9) | Fourth | 9½ out |
| Thursday, August 29 |
| » Lost to Red Sox (72-57), 3-2 | Comiskey Park I (39-26) | 65-66 | |
| » W: Bill Lee (15-11) L: Wilbur Wood (19-16) S: Diego Segui (9) | Fourth | 10 out |
| Friday, August 30 |
| » Lost to Yankees (68-62), 8-5 | Comiskey Park I (39-27) | 65-67 | Lost 2 |
| » W: Cecil Upshaw (1-5) L: Rich Gossage (3-5) | Fourth | 11 out |
| Saturday, August 31 |
| » Lost to Yankees (69-62), 18-6 | Comiskey Park I (39-28) | 65-68 | Lost 3 |
| » W: Doc Medich (16-12) L: Jim Kaat (14-13) S: Sparky Lyle (13) | Fourth | 11 out |
| Sunday, September 1 |
| » Lost to Yankees (70-62), 7-5 | Comiskey Park I (39-29) | 65-69 | Lost 4 |
| » W: Pat Dobson (14-14) L: Bart Johnson (6-3) | Fifth | 12 out |
| Monday, September 2 |
| » Defeated Royals (69-65), 6-4 | Royals Stadium (3-4) | 66-69 | |
| » W: Wilbur Wood (20-16) L: Doug Bird (6-4) | Fifth | 12 out |
| Tuesday, September 3 |
| » Defeated Royals (69-66), 2-1 | Royals Stadium (4-4) | 67-69 | Won 2 |
| » W: Jack Kucek (1-0) L: Bruce Dal Canton (8-8) S: Terry Forster (19) | Fourth | 12 out |
| Wednesday, September 4 |
| » Defeated Royals (69-67), 7-0 | Royals Stadium (5-4) | 68-69 | Won 3 |
| » W: Jim Kaat (15-13) L: Paul Splittorff (13-15) | Fourth | 11 out |
| » Major-league debuts: Dennis Leonard (Royals) |
| Thursday, September 5 |
| » Defeated Angels (53-85), 1-0 | Anaheim Stadium (3-3) | 69-69 | Won 4 |
| » W: Bart Johnson (7-3) L: Ed Figueroa (2-7) S: Terry Forster (20) | Fourth | 11 out |
| Friday, September 6 |
| » Lost to Angels (54-85), 4-2 | Anaheim Stadium (3-4) | 69-70 | |
| » W: Frank Tanana (10-17) L: Wilbur Wood (20-17) S: Orlando Pena (2) | Fourth | 11 out |
| Saturday, September 7 |
| » Lost to Angels (55-85), 3-1 | Anaheim Stadium (3-5) | 69-71 | Lost 2 |
| » W: Nolan Ryan (18-15) L: Jack Kucek (1-1) | Fourth | 11 out |
| Sunday, September 8 |
| » Defeated Angels (55-86), 1-0 | Anaheim Stadium (4-5) | 70-71 | |
| » W: Jim Kaat (16-13) L: Andy Hassler (4-10) S: Terry Forster (21) | Fourth | 10 out |
| Monday, September 9 |
| » Lost to Twins (70-71), 3-1 | Metropolitan Stadium (3-5) | 70-72 | |
| » W: Dave Goltz (8-8) L: Bart Johnson (7-4) | Fourth | 11½ out |
| Tuesday, September 10 |
| » Lost to Twins (71-71), 8-7 | Metropolitan Stadium (3-6) | 70-73 | Lost 2 |
| » W: Tom Johnson (1-0) L: Rich Gossage (3-6) | Fifth | 12 out |
| » Major-league debuts: Tom Johnson (Twins) |
| Wednesday, September 11 |
| » Lost to Rangers (76-68), 6-2 | Comiskey Park I (39-30) | 70-74 | Lost 3 |
| » W: Jim Bibby (19-16) L: Jack Kucek (1-2) | Fifth | 12 out |
| Thursday, September 12 |
| » Tied Rangers, 2-2 | Comiskey Park I (39-30) | 70-74 | |
| » Starters: Steve Hargan vs Stan Bahnsen | |
