| Saturday, January 5 |
| Future Oriole Ryan Minor is born in Canton, OH. |
| Wednesday, February 13 |
| Future Oriole Howie Clark is born in San Diego, CA. |
| Friday, March 8 |
| Future Oriole Mike Moriarty is born in Camden, NJ. |
| Tuesday, March 19 |
| Future Oriole Rocky Coppinger is born in ElPaso, TX. |
| Thursday, April 4 |
| » Major-league debuts: Jim Sundberg (Rangers) |
| Friday, April 5 |
| » Defeated Tigers (0-1), 3-2 | Memorial Stadium (1-0) | 1-0 | |
| » W: Jim Palmer (1-0) L: Mickey Lolich (0-1) S: Grant Jackson (1) | First | -- |
| Saturday, April 6 |
| » Lost to Tigers (1-1), 3-2 | Memorial Stadium (1-1) | 1-1 | |
| » W: John Hiller (1-0) L: Dave McNally (0-1) | Second | ½ out |
| Future Oriole Danny Clyburn is born in Lancaster, SC. |
| Sunday, April 7 |
| » Defeated Tigers (1-2), 5-1 | Memorial Stadium (2-1) | 2-1 | |
| » W: Ross Grimsley (1-0) L: Woodie Fryman (0-1) | Third | 1 out |
| » Lost to Tigers (2-2), 8-4 | Memorial Stadium (2-2) | 2-2 | |
| » W: John Hiller (2-0) L: Grant Jackson (0-1) | Third | 1 out |
| Thursday, April 11 |
| » Defeated Red Sox (1-2), 7-6 | Fenway Park (1-0) | 3-2 | |
| » W: Bob Reynolds (1-0) L: Diego Segui (1-1) | Third | 1 out |
| Friday, April 12 |
| » Defeated Brewers (3-2), 5-3 | County Stadium (1-0) | 4-2 | Won 2 |
| » W: Dave McNally (1-1) L: Jim Slaton (1-1) S: Grant Jackson (2) | First | -- |
| Saturday, April 13 |
| » Lost to Brewers (4-2), 3-2 | County Stadium (1-1) | 4-3 | |
| » W: Eduardo Rodriguez (1-0) L: Ross Grimsley (1-1) | Third | ½ out |
| Monday, April 15 |
| » Lost to Brewers (5-2), 6-1 | County Stadium (1-2) | 4-4 | Lost 2 |
| » W: Clyde Wright (2-0) L: Mike Cuellar (0-1) | Fourth | 1½ out |
| Wednesday, April 17 |
| » Defeated Tigers (4-7), 6-1 | Tiger Stadium (1-0) | 5-4 | |
| » W: Jim Palmer (2-0) L: Woodie Fryman (0-2) | Second | 1 out |
| Friday, April 19 |
| » Defeated Yankees (7-6), 5-3 | Memorial Stadium (3-2) | 6-4 | Won 2 |
| » W: Ross Grimsley (2-1) L: Steve Kline (2-1) S: Grant Jackson (3) | Second | ½ out |
| Saturday, April 20 |
| » Lost to Yankees (8-6), 4-3 | Memorial Stadium (3-3) | 6-5 | |
| » W: Mel Stottlemyre (3-1) L: Grant Jackson (0-2) | Fourth | 1½ out |
| Sunday, April 21 |
| » Defeated Yankees (8-7), 6-5 | Memorial Stadium (4-3) | 7-5 | |
| » W: Doyle Alexander (1-0) L: Tom Buskey (0-1) | Fourth | 1 out |
| » Lost to Yankees (9-7), 3-0 | Memorial Stadium (4-4) | 7-6 | |
| » W: Sam McDowell (1-1) L: Mike Cuellar (0-2) S: Fred Beene (1) | Fourth | 1 out |
| Tuesday, April 23 |
| » Defeated Angels (9-7), 4-3 | Memorial Stadium (5-4) | 8-6 | |
| » W: Bob Reynolds (2-0) L: Dave Sells (1-1) | Third | ½ out |
| Wednesday, April 24 |
| » Defeated Angels (9-8), 4-3 | Memorial Stadium (6-4) | 9-6 | Won 2 |
| » W: Dave McNally (2-1) L: Bill Singer (2-2) S: Bob Reynolds (1) | First | -- |
| Friday, April 26 |
| » Defeated Athletics (9-8), 6-5 | Memorial Stadium (7-4) | 10-6 | Won 3 |
| » W: Grant Jackson (1-2) L: Paul Lindblad (1-1) | First | -- |
| Saturday, April 27 |
| » Lost to Athletics (10-8), 11-5 | Memorial Stadium (7-5) | 10-7 | |
| » W: Catfish Hunter (4-1) L: Mike Cuellar (0-3) | Second | 1 out |
| Sunday, April 28 |
| » Defeated Athletics (10-9), 4-3 | Memorial Stadium (8-5) | 11-7 | |
| » W: Ross Grimsley (3-1) L: Ken Holtzman (1-3) S: Bob Reynolds (2) | First | -- |
| Monday, April 29 |
| » Major-league debuts: Jim Todd (Cubs) |
| Tuesday, April 30 |
| » Lost to White Sox (8-11), 2-1 | Comiskey Park I (0-1) | 11-8 | |
| » W: Stan Bahnsen (3-2) L: Jim Palmer (2-1) | First | -- |
| Wednesday, May 1 |
| » Lost to White Sox (9-11), 2-0 | Comiskey Park I (0-2) | 11-9 | Lost 2 |
| » W: Jim Kaat (3-1) L: Dave McNally (2-2) S: Terry Forster (3) | Third | 2 out |
| Friday, May 3 |
| » Lost to Angels (13-11), 2-0 | Anaheim Stadium (0-1) | 11-10 | Lost 3 |
| » W: Frank Tanana (3-2) L: Ross Grimsley (3-2) S: Rudy May (2) | Fourth | 2 out |
| Saturday, May 4 |
| » Lost to Angels (14-11), 3-1 | Anaheim Stadium (0-2) | 11-11 | Lost 4 |
| » W: Bill Singer (4-2) L: Jim Palmer (2-2) | Fourth | 2 out |
| Sunday, May 5 |
| » Lost to Angels (15-11), 8-7 | Anaheim Stadium (0-3) | 11-12 | Lost 5 |
| » W: Dick Selma (2-1) L: Grant Jackson (1-3) | Fourth | 2 out |
| Monday, May 6 |
| » Defeated Athletics (12-14), 6-3 | Oakland-Alameda County Stadium (1-0) | 12-12 | |
| » W: Mike Cuellar (1-3) L: Paul Lindblad (1-2) | Third | 2 out |
| Tuesday, May 7 |
| » Defeated Athletics (12-15), 9-3 | Oakland-Alameda County Stadium (2-0) | 13-12 | Won 2 |
| » W: Ross Grimsley (4-2) L: Ken Holtzman (2-4) | Second | 2 out |
| Wednesday, May 8 |
| » Lost to Athletics (13-15), 7-3 | Oakland-Alameda County Stadium (2-1) | 13-13 | |
| » W: Vida Blue (1-4) L: Jim Palmer (2-3) | Third | 2 out |
| Friday, May 10 |
| » Defeated Indians (15-14), 3-1 | Cleveland Stadium (1-0) | 14-13 | |
| » W: Dave McNally (3-2) L: Steve Kline (3-4) | Second | 2½ out |
| Saturday, May 11 |
| » Defeated Indians (15-15), 12-1 | Cleveland Stadium (2-0) | 15-13 | Won 2 |
| » W: Mike Cuellar (2-3) L: Fritz Peterson (2-1) | Second | 2½ out |
| Monday, May 13 |
| » Lost to Brewers (14-13), 9-4 | Memorial Stadium (8-6) | 15-14 | |
| » W: Ed Sprague (1-0) L: Ross Grimsley (4-3) S: Tom Murphy (3) | Second | 1 out |
| Tuesday, May 14 |
| » Lost to Brewers (15-13), 8-3 | Memorial Stadium (8-7) | 15-15 | Lost 2 |
| » W: Bill Champion (1-0) L: Jim Palmer (2-4) | Third | 1 out |
| Wednesday, May 15 |
| » Defeated Brewers (15-14), 6-5 | Memorial Stadium (9-7) | 16-15 | |
| » W: Bob Reynolds (3-0) L: Jim Slaton (4-4) | Second | 1 out |
| Friday, May 17 |
| » Defeated Red Sox (16-19), 6-0 | Memorial Stadium (10-7) | 17-15 | Won 2 |
| » W: Mike Cuellar (3-3) L: Bill Lee (4-4) | First | -- |
| Saturday, May 18 |
| » Lost to Red Sox (17-19), 10-2 | Memorial Stadium (10-8) | 17-16 | |
| » W: Luis Tiant (3-5) L: Ross Grimsley (4-4) | Third | 1 out |
| Sunday, May 19 |
| » Lost to Red Sox (18-19), 11-2 | Memorial Stadium (10-9) | 17-17 | Lost 2 |
| » W: Reggie Cleveland (2-4) L: Dave McNally (3-3) | Sixth | 1 out |
| » Lost to Red Sox (19-19), 6-4 | Memorial Stadium (10-10) | 17-18 | Lost 3 |
| » W: Dick Drago (3-1) L: Doyle Alexander (1-1) | Sixth | 1 out |
| Monday, May 20 |
| » Major-league debuts: Kent Tekulve (Pirates) |
| Tuesday, May 21 |
| » Defeated Indians (19-19), 7-1 | Memorial Stadium (11-10) | 18-18 | |
| » W: Mike Cuellar (4-3) L: Steve Kline (3-6) | Third | 1½ out |
| Wednesday, May 22 |
| » Defeated Indians (19-20), 1-0 | Memorial Stadium (12-10) | 19-18 | Won 2 |
| » W: Ross Grimsley (5-4) L: Tom Buskey (0-2) | Third | ½ out |
| Future Oriole John Bale is born in Cheverly, MD. |
| Thursday, May 23 |
| » Lost to Indians (20-20), 2-0 | Memorial Stadium (12-11) | 19-19 | |
| » W: Gaylord Perry (7-1) L: Jim Palmer (2-5) | Third | 1½ out |
| Friday, May 24 |
| » Defeated Yankees (20-24), 6-3 | Shea Stadium (1-0) | 20-19 | |
| » W: Dave McNally (4-3) L: Mel Stottlemyre (5-6) S: Bob Reynolds (3) | Third | 1 out |
| Saturday, May 25 |
| » Defeated Yankees (20-25), 5-1 | Shea Stadium (2-0) | 21-19 | Won 2 |
| » W: Mike Cuellar (5-3) L: Pat Dobson (3-7) | Second | ½ out |
| Sunday, May 26 |
| » Lost to Yankees (21-25), 6-5 | Shea Stadium (2-1) | 21-20 | |
| » W: Dick Tidrow (4-4) L: Ross Grimsley (5-5) S: Sparky Lyle (7) | Third | 1½ out |
| » Lost to Yankees (22-25), 7-5 | Shea Stadium (2-2) | 21-21 | Lost 2 |
| » W: Mike Wallace (2-0) L: Doyle Alexander (1-2) S: Cecil Upshaw (1) | Third | 1½ out |
| Monday, May 27 |
| » Lost to Royals (23-21), 9-1 | Royals Stadium (0-1) | 21-22 | Lost 3 |
| » W: Bruce Dal Canton (3-2) L: Jim Palmer (2-6) | Third | 2½ out |
| Tuesday, May 28 |
| » Lost to Royals (24-21), 9-5 | Royals Stadium (0-2) | 21-23 | Lost 4 |
| » W: Doug Bird (3-1) L: Bob Reynolds (3-1) | Fifth | 3½ out |
| Wednesday, May 29 |
| » Defeated Royals (24-22), 10-3 | Royals Stadium (1-2) | 22-23 | |
| » W: Mike Cuellar (6-3) L: Steve Busby (7-4) | Third | 3 out |
| Friday, May 31 |
| » Lost to Rangers (24-24), 7-6 | Arlington Stadium (0-1) | 22-24 | |
| » W: Steve Foucault (2-2) L: Bob Reynolds (3-2) | Third | 3 out |
| Saturday, June 1 |
| » Lost to Rangers (25-24), 4-2 | Arlington Stadium (0-2) | 22-25 | Lost 2 |
| » W: Jim Bibby (7-7) L: Dave McNally (4-4) S: Steve Foucault (3) | Fifth | 3½ out |
| Sunday, June 2 |
| » Defeated Rangers (25-25), 6-5 | Arlington Stadium (1-2) | 23-25 | |
| » W: Wayne Garland (1-0) L: Jackie Brown (3-2) | Fifth | 3½ out |
| Monday, June 3 |
| » Defeated Royals (25-25), 4-3 | Memorial Stadium (13-11) | 24-25 | Won 2 |
| » W: Doyle Alexander (2-2) L: Steve Busby (7-5) S: Grant Jackson (4) | Third | 2½ out |
| Tuesday, June 4 |
| » Lost to Royals (26-25), 8-0 | Memorial Stadium (13-12) | 24-26 | |
| » W: Al Fitzmorris (5-2) L: Ross Grimsley (5-6) | Fourth | 3½ out |
| Wednesday, June 5 |
| » Defeated Royals (26-26), 5-4 | Memorial Stadium (14-12) | 25-26 | |
| » W: Bob Reynolds (4-2) L: Doug Bird (3-2) | Fourth | 3½ out |
| Friday, June 7 |
| » Lost to Rangers (27-26), 5-3 | Memorial Stadium (14-13) | 25-27 | |
| » W: Steve Hargan (4-4) L: Jim Palmer (2-7) S: Steve Foucault (4) | Fourth | 3½ out |
| Future Oriole Chris Richard is born in San Diego, CA. |
| Saturday, June 8 |
| » Defeated Rangers (27-27), 6-4 | Memorial Stadium (15-13) | 26-27 | |
| » W: Mike Cuellar (7-3) L: Fergie Jenkins (7-6) S: Grant Jackson (5) | Fourth | 3 out |
| Sunday, June 9 |
| » Lost to Rangers (28-27), 3-2 | Memorial Stadium (15-14) | 26-28 | |
| » W: Jim Bibby (8-8) L: Ross Grimsley (5-7) S: Steve Foucault (5) | Sixth | 3½ out |
| Monday, June 10 |
| » Lost to Twins (23-29), 9-1 | Metropolitan Stadium (0-1) | 26-29 | Lost 2 |
| » W: Bill Butler (1-1) L: Dave McNally (4-5) S: Bill Hands (1) | Sixth | 4½ out |
| Tuesday, June 11 |
| » Defeated Twins (23-30), 4-2 | Metropolitan Stadium (1-1) | 27-29 | |
| » W: Jim Palmer (3-7) L: Bert Blyleven (5-8) S: Bob Reynolds (4) | Sixth | 4½ out |
| Wednesday, June 12 |
| » Defeated Twins (23-31), 4-3 | Metropolitan Stadium (2-1) | 28-29 | Won 2 |
| » W: Mike Cuellar (8-3) L: Vic Albury (2-5) | Sixth | 4½ out |
| Friday, June 14 |
| » Defeated White Sox (26-28), 2-1 | Memorial Stadium (16-14) | 29-29 | Won 3 |
| » W: Ross Grimsley (6-7) L: Terry Forster (3-5) | Fourth | 3½ out |
| Saturday, June 15 |
| » Defeated White Sox (26-29), 4-3 | Memorial Stadium (17-14) | 30-29 | Won 4 |
| » W: Dave McNally (5-5) L: Cy Acosta (0-2) | Third | 3½ out |
| Sunday, June 16 |
| » Lost to White Sox (27-29), 9-1 | Memorial Stadium (17-15) | 30-30 | |
| » W: Wilbur Wood (11-7) L: Jim Palmer (3-8) | Fifth | 4½ out |
| Monday, June 17 |
| » Defeated Twins (25-34), 1-0 | Memorial Stadium (18-15) | 31-30 | |
| » W: Mike Cuellar (9-3) L: Vic Albury (2-6) | Fifth | 3½ out |
| Tuesday, June 18 |
| » Defeated Twins (25-35), 10-1 | Memorial Stadium (19-15) | 32-30 | Won 2 |
| » W: Ross Grimsley (7-7) L: Joe Decker (7-5) | Third | 3½ out |
| Future Oriole Carlos Mendez is born in Caracas, Venezuela. |
| Wednesday, June 19 |
| » Defeated Twins (25-36), 6-5 | Memorial Stadium (20-15) | 33-30 | Won 3 |
| » W: Dave McNally (6-5) L: Bill Butler (1-2) S: Wayne Garland (1) | Second | 3½ out |
| Thursday, June 20 |
| » Lost to Brewers (30-31), 6-0 | County Stadium (1-3) | 33-31 | |
| » W: Ed Sprague (3-1) L: Doyle Alexander (2-3) | Third | 4 out |
| Friday, June 21 |
| » Lost to Brewers (31-31), 8-6 | County Stadium (1-4) | 33-32 | Lost 2 |
| » W: Jim Slaton (7-8) L: Wayne Garland (1-1) S: Tom Murphy (6) | Fourth | 4½ out |
| Saturday, June 22 |
| » Defeated Brewers (31-32), 7-2 | County Stadium (2-4) | 34-32 | |
| » W: Ross Grimsley (8-7) L: Kevin Kobel (3-6) | Fourth | 4 out |
| Sunday, June 23 |
| » Lost to Brewers (32-32), 9-4 | County Stadium (2-5) | 34-33 | |
| » W: Clyde Wright (6-9) L: Dave McNally (6-6) | Fourth | 5 out |
| Monday, June 24 |
| » Defeated Tigers (35-32), 3-1 | Memorial Stadium (21-15) | 35-33 | |
| » W: Doyle Alexander (3-3) L: Lerrin LaGrow (5-7) | Third | 5 out |
| Tuesday, June 25 |
| » Lost to Tigers (36-32), 2-0 | Memorial Stadium (21-16) | 35-34 | |
| » W: Mickey Lolich (10-7) L: Mike Cuellar (9-4) | Fourth | 5½ out |
| Wednesday, June 26 |
| » Defeated Tigers (36-33), 5-4 | Memorial Stadium (22-16) | 36-34 | |
| » W: Ross Grimsley (9-7) L: John Hiller (9-5) | Fourth | 4½ out |
| Saturday, June 29 |
| » Defeated Yankees (35-38), 2-0 | Memorial Stadium (23-16) | 37-34 | Won 2 |
| » W: Dave McNally (7-6) L: Dick Tidrow (5-8) | Third | 3½ out |
| Sunday, June 30 |
| » Defeated Yankees (35-39), 3-0 | Memorial Stadium (24-16) | 38-34 | Won 3 |
| » W: Mike Cuellar (10-4) L: Rudy May (1-2) | Third | 2½ out |
| Monday, July 1 |
| » Lost to Red Sox (42-32), 6-4 | Memorial Stadium (24-17) | 38-35 | |
| » W: Bill Lee (9-7) L: Doyle Alexander (3-4) S: Diego Segui (6) | Third | 3½ out |
| Tuesday, July 2 |
| » Lost to Red Sox (43-32), 9-6 | Memorial Stadium (24-18) | 38-36 | Lost 2 |
| » W: Diego Segui (5-4) L: Dave Johnson (0-1) | Fourth | 4½ out |
| » Major-league debuts: Dave Johnson (Orioles) |
| Wednesday, July 3 |
| » Defeated Red Sox (43-33), 9-2 | Fenway Park (2-0) | 39-36 | |
| » W: Doyle Alexander (4-4) L: Dick Drago (5-4) | Fourth | 2½ out |
| » Defeated Red Sox (43-34), 6-4 | Fenway Park (3-0) | 40-36 | Won 2 |
| » W: Wayne Garland (2-1) L: Reggie Cleveland (6-6) S: Dave McNally (1) | Fourth | 2½ out |
| » Major-league debuts: Tim Blackwell (Red Sox) |
| Thursday, July 4 |
| » Defeated Red Sox (43-35), 10-6 | Fenway Park (4-0) | 41-36 | Won 3 |
| » W: Jesse Jefferson (1-0) L: Luis Tiant (11-7) | Third | 1½ out |
| Friday, July 5 |
| » Lost to Athletics (46-35), 6-0 | Oakland-Alameda County Stadium (2-2) | 41-37 | |
| » W: Catfish Hunter (11-8) L: Mike Cuellar (10-5) | Fourth | 2½ out |
| Saturday, July 6 |
| » Defeated Athletics (46-36), 3-0 | Oakland-Alameda County Stadium (3-2) | 42-37 | |
| » W: Ross Grimsley (10-7) L: Dave Hamilton (5-2) | Third | 2½ out |
| Sunday, July 7 |
| » Defeated Athletics (46-37), 4-1 | Oakland-Alameda County Stadium (4-2) | 43-37 | Won 2 |
| » W: Dave McNally (8-6) L: Ken Holtzman (9-10) | Third | 2½ out |
| Monday, July 8 |
| » Defeated Angels (32-54), 6-5 | Anaheim Stadium (1-3) | 44-37 | Won 3 |
| » W: Wayne Garland (3-1) L: Andy Hassler (1-4) S: Dave Johnson (1) | Second | 1½ out |
| Tuesday, July 9 |
| » Defeated Angels (32-55), 3-1 | Anaheim Stadium (2-3) | 45-37 | Won 4 |
| » W: Mike Cuellar (11-5) L: Dick Lange (3-5) S: Bob Reynolds (5) | Second | ½ out |
| Wednesday, July 10 |
| » Defeated Angels (32-56), 9-1 | Anaheim Stadium (3-3) | 46-37 | Won 5 |
| » W: Ross Grimsley (11-7) L: Nolan Ryan (10-9) | Second | 1 out |
| Thursday, July 11 |
| » Lost to White Sox (41-43), 4-3 | Comiskey Park I (0-3) | 46-38 | |
| » W: Bart Johnson (2-0) L: Bob Reynolds (4-3) | Third | ½ out |
| Friday, July 12 |
| » Lost to White Sox (42-43), 4-3 | Comiskey Park I (0-4) | 46-39 | Lost 2 |
| » W: Rich Gossage (1-3) L: Doyle Alexander (4-5) | Third | 1 out |
| Saturday, July 13 |
| » Defeated White Sox (42-44), 2-1 | Comiskey Park I (1-4) | 47-39 | |
| » W: Mike Cuellar (12-5) L: Wilbur Wood (14-11) S: Grant Jackson (6) | Second | 1 out |
| Sunday, July 14 |
| » Lost to White Sox (43-44), 3-1 | Comiskey Park I (1-5) | 47-40 | |
| » W: Stan Bahnsen (8-11) L: Ross Grimsley (11-8) S: Rich Gossage (1) | Third | ½ out |
| Monday, July 15 |
| » Lost to Athletics (51-39), 6-4 | Memorial Stadium (24-19) | 47-41 | Lost 2 |
| » W: Blue Moon Odom (1-2) L: Wayne Garland (3-2) | Third | ½ out |
| Tuesday, July 16 |
| » Lost to Athletics (52-39), 4-3 | Memorial Stadium (24-20) | 47-42 | Lost 3 |
| » W: Ken Holtzman (10-11) L: Doyle Alexander (4-6) S: Rollie Fingers (8) | Third | ½ out |
| Wednesday, July 17 |
| » Lost to Athletics (53-39), 2-0 | Memorial Stadium (24-21) | 47-43 | Lost 4 |
| » W: Vida Blue (10-9) L: Mike Cuellar (12-6) S: Rollie Fingers (9) | Third | 1½ out |
| Friday, July 19 |
| » Defeated Angels (37-58), 5-4 | Memorial Stadium (25-21) | 48-43 | |
| » W: Don Hood (1-0) L: Skip Lockwood (2-4) | Second | 1 out |
| » Major-league debuts: Bruce Bochte (Angels) |
| Saturday, July 20 |
| » Lost to Angels (38-58), 2-0 | Memorial Stadium (25-22) | 48-44 | |
| » W: Nolan Ryan (12-9) L: Wayne Garland (3-3) | Second | ½ out |
| » Defeated Angels (38-59), 5-2 | Memorial Stadium (26-22) | 49-44 | |
| » W: Mike Cuellar (13-6) L: Ed Figueroa (1-2) | Second | ½ out |
| Sunday, July 21 |
| » Lost to Angels (39-59), 6-4 | Memorial Stadium (26-23) | 49-45 | |
| » W: Frank Tanana (6-13) L: Dave McNally (8-7) | Third | ½ out |
| Thursday, July 25 |
| » Lost to Indians (49-44), 8-7 | Cleveland Stadium (2-1) | 49-46 | Lost 2 |
| » W: Dick Bosman (3-0) L: Dave McNally (8-8) S: Tom Buskey (7) | Third | 2 out |
| » Lost to Indians (50-44), 5-4 | Cleveland Stadium (2-2) | 49-47 | Lost 3 |
| » W: Tom Hilgendorf (3-2) L: Bob Reynolds (4-4) | Third | 2 out |
| Friday, July 26 |
| » Defeated Indians (50-45), 9-5 | Cleveland Stadium (3-2) | 50-47 | |
| » W: Dave Johnson (1-1) L: Gaylord Perry (15-4) | Third | 1 out |
| Saturday, July 27 |
| » Lost to Brewers (48-50), 5-3 | Memorial Stadium (26-24) | 50-48 | |
| » W: Bill Champion (5-1) L: Wayne Garland (3-4) S: Tom Murphy (11) | Third | 2 out |
| Sunday, July 28 |
| » Lost to Brewers (49-50), 4-0 | Memorial Stadium (26-25) | 50-49 | Lost 2 |
| » W: Jim Slaton (8-11) L: Doyle Alexander (4-7) | Third | 3 out |
| Monday, July 29 |
| » Defeated Brewers (49-51), 6-2 | Memorial Stadium (27-25) | 51-49 | |
| » W: Ross Grimsley (12-8) L: Clyde Wright (8-14) | Third | 3 out |
| Tuesday, July 30 |
| » Lost to Indians (52-47), 8-6 | Memorial Stadium (27-26) | 51-50 | |
| » W: Dick Bosman (4-0) L: Mike Cuellar (13-7) | Third | 3 out |
| Wednesday, July 31 |
| » Defeated Indians (52-48), 7-4 | Memorial Stadium (28-26) | 52-50 | |
| » W: Dave McNally (9-8) L: Gaylord Perry (15-5) | Third | 3 out |
| Thursday, August 1 |
| » Lost to Red Sox (56-47), 11-3 | Fenway Park (4-1) | 52-51 | |
| » W: Bill Lee (12-9) L: Wayne Garland (3-5) | Third | 4 out |
| Friday, August 2 |
| » Lost to Red Sox (57-47), 7-5 | Fenway Park (4-2) | 52-52 | Lost 2 |
| » W: Juan Marichal (3-1) L: Doyle Alexander (4-8) | Third | 5 out |
| Saturday, August 3 |
| » Defeated Tigers (51-54), 6-2 | Tiger Stadium (2-0) | 53-52 | |
| » W: Ross Grimsley (13-8) L: Mickey Lolich (11-14) | Third | 4 out |
| Sunday, August 4 |
| » Lost to Tigers (52-54), 6-1 | Tiger Stadium (2-1) | 53-53 | |
| » W: Joe Coleman (10-9) L: Mike Cuellar (13-8) | Third | 4½ out |
| » Defeated Tigers (52-55), 9-3 | Tiger Stadium (3-1) | 54-53 | |
| » W: Dave McNally (10-8) L: Lerrin LaGrow (7-12) | Third | 4½ out |
| Monday, August 5 |
| » Defeated Tigers (52-56), 7-4 | Tiger Stadium (4-1) | 55-53 | Won 2 |
| » W: Wayne Garland (4-5) L: Woodie Fryman (5-7) S: Ross Grimsley (1) | Third | 3 out |
| » Defeated Tigers (52-57), 6-3 | Tiger Stadium (5-1) | 56-53 | Won 3 |
| » W: Doyle Alexander (5-8) L: Luke Walker (4-3) S: Grant Jackson (7) | Third | 3 out |
| Tuesday, August 6 |
| » Defeated Yankees (53-56), 4-1 | Shea Stadium (3-2) | 57-53 | Won 4 |
| » W: Dave Johnson (2-1) L: Dick Tidrow (8-9) S: Grant Jackson (8) | Third | 3½ out |
| Wednesday, August 7 |
| » Lost to Yankees (54-56), 4-3 | Shea Stadium (3-3) | 57-54 | |
| » W: Pat Dobson (10-13) L: Ross Grimsley (13-9) S: Cecil Upshaw (4) | Third | 4½ out |
| Friday, August 9 |
| » Lost to Twins (55-60), 6-2 | Metropolitan Stadium (2-2) | 57-55 | Lost 2 |
| » W: Bill Hands (4-4) L: Dave McNally (10-9) | Third | 5 out |
| Saturday, August 10 |
| » Lost to Twins (56-60), 5-1 | Metropolitan Stadium (2-3) | 57-56 | Lost 3 |
| » W: Bert Blyleven (11-13) L: Mike Cuellar (13-9) | Third | 5 out |
| Sunday, August 11 |
| » Lost to Twins (57-60), 5-4 | Metropolitan Stadium (2-4) | 57-57 | Lost 4 |
| » W: Dave Goltz (5-6) L: Ross Grimsley (13-10) S: Bill Campbell (16) | Third | 6 out |
| Tuesday, August 13 |
| » Defeated White Sox (58-57), 8-2 | Memorial Stadium (29-26) | 58-57 | |
| » W: Jim Palmer (4-8) L: Bart Johnson (4-1) S: Grant Jackson (9) | Third | 5½ out |
| Wednesday, August 14 |
| » Lost to White Sox (59-57), 5-4 | Memorial Stadium (29-27) | 58-58 | |
| » W: Terry Forster (7-7) L: Doyle Alexander (5-9) | Third | 5½ out |
| Thursday, August 15 |
| » Defeated White Sox (59-58), 2-1 | Memorial Stadium (30-27) | 59-58 | |
| » W: Mike Cuellar (14-9) L: Jim Kaat (13-10) | Third | 5 out |
| Friday, August 16 |
| » Defeated Royals (62-55), 1-0 | Memorial Stadium (31-27) | 60-58 | Won 2 |
| » W: Ross Grimsley (14-10) L: Bruce Dal Canton (7-6) | Third | 5 out |
| Saturday, August 17 |
| » Lost to Royals (63-55), 3-2 | Memorial Stadium (31-28) | 60-59 | |
| » W: Steve Mingori (2-2) L: Bob Reynolds (4-5) | Third | 5 out |
| Sunday, August 18 |
| » Defeated Royals (63-56), 1-0 | Memorial Stadium (32-28) | 61-59 | |
| » W: Dave McNally (11-9) L: Steve Busby (18-10) | Third | 5 out |
| Tuesday, August 20 |
| » Defeated Rangers (61-62), 2-1 | Memorial Stadium (33-28) | 62-59 | Won 2 |
| » W: Mike Cuellar (15-9) L: Jackie Brown (9-10) | Third | 5½ out |
| Wednesday, August 21 |
| » Lost to Rangers (62-62), 5-1 | Memorial Stadium (33-29) | 62-60 | |
| » W: Jim Bibby (18-14) L: Ross Grimsley (14-11) S: Steve Foucault (10) | Third | 6½ out |
| Thursday, August 22 |
| » Lost to Rangers (63-62), 6-2 | Memorial Stadium (33-30) | 62-61 | Lost 2 |
| » W: Fergie Jenkins (18-11) L: Jim Palmer (4-9) | Third | 7 out |
| Friday, August 23 |
| » Defeated Twins (60-66), 4-1 | Memorial Stadium (34-30) | 63-61 | |
| » W: Dave McNally (12-9) L: Dave Goltz (6-7) | Second | 7 out |
| Saturday, August 24 |
| » Lost to Twins (61-66), 9-5 | Memorial Stadium (34-31) | 63-62 | |
| » W: Ray Corbin (7-5) L: Mike Cuellar (15-10) S: Bill Campbell (18) | Third | 7 out |
| Sunday, August 25 |
| » Lost to Twins (62-66), 5-1 | Memorial Stadium (34-32) | 63-63 | Lost 2 |
| » W: Bert Blyleven (12-15) L: Ross Grimsley (14-12) | Third | 7 out |
| Tuesday, August 27 |
| » Lost to Rangers (66-63), 2-1 | Arlington Stadium (1-3) | 63-64 | Lost 3 |
| » W: Fergie Jenkins (19-11) L: Jim Palmer (4-10) | Fourth | 8 out |
| Wednesday, August 28 |
| » Lost to Rangers (67-63), 4-2 | Arlington Stadium (1-4) | 63-65 | Lost 4 |
| » W: Jackie Brown (10-10) L: Dave McNally (12-10) | Fourth | 8 out |
| Thursday, August 29 |
| » Defeated Rangers (67-64), 6-2 | Arlington Stadium (2-4) | 64-65 | |
| » W: Ross Grimsley (15-12) L: Jim Bibby (18-15) | Fourth | 8 out |
| Friday, August 30 |
| » Defeated Royals (69-62), 9-2 | Royals Stadium (2-2) | 65-65 | Won 2 |
| » W: Mike Cuellar (16-10) L: Bruce Dal Canton (8-7) | Fourth | 7 out |
| Future Oriole Kris Foster is born in Evanston, IL. |
| Saturday, August 31 |
| » Defeated Royals (69-63), 3-2 | Royals Stadium (3-2) | 66-65 | Won 3 |
| » W: Jim Palmer (5-10) L: Paul Splittorff (13-14) S: Grant Jackson (10) | Third | 6 out |
| Sunday, September 1 |
| » Defeated Royals (69-64), 7-1 | Royals Stadium (4-2) | 67-65 | Won 4 |
| » W: Dave McNally (13-10) L: Steve Busby (19-12) | Third | 5 out |
| » Major-league debuts: Aurelio Lopez (Royals) |
| Monday, September 2 |
| » Defeated Red Sox (72-61), 1-0 | Memorial Stadium (35-32) | 68-65 | Won 5 |
| » W: Ross Grimsley (16-12) L: Luis Tiant (20-10) | Third | 3 out |
| » Defeated Red Sox (72-62), 1-0 | Memorial Stadium (36-32) | 69-65 | Won 6 |
| » W: Mike Cuellar (17-10) L: Bill Lee (15-12) | Third | 3 out |
| Wednesday, September 4 |
| » Defeated Red Sox (72-63), 6-0 | Memorial Stadium (37-32) | 70-65 | Won 7 |
| » W: Jim Palmer (6-10) L: Roger Moret (7-8) | Second | 2 out |
| Thursday, September 5 |
| Future Oriole Calvin Maduro is born in Santa Cruz, Aruba. |
| Friday, September 6 |
| » Defeated Indians (67-67), 2-0 | Cleveland Stadium (4-2) | 71-65 | Won 8 |
| » W: Dave McNally (14-10) L: Fritz Peterson (8-11) | Second | 1½ out |
| » Defeated Indians (67-68), 1-0 | Cleveland Stadium (5-2) | 72-65 | Won 9 |
| » W: Mike Cuellar (18-10) L: Jim Kern (0-1) | Second | 1½ out |
| » Major-league debuts: Jim Kern (Indians) |
| Saturday, September 7 |
| » Defeated Indians (67-69), 3-2 | Cleveland Stadium (6-2) | 73-65 | Won 10 |
| » W: Ross Grimsley (17-12) L: Gaylord Perry (18-10) S: Bob Reynolds (6) | Second | 1 out |
| Sunday, September 8 |
| » Lost to Indians (68-69), 7-4 | Cleveland Stadium (6-3) | 73-66 | |
| » W: Jim Perry (15-10) L: Jim Palmer (6-11) S: Tom Buskey (15) | Second | 1 out |
| Monday, September 9 |
| » Defeated Brewers (67-75), 6-5 | County Stadium (3-5) | 74-66 | |
| » W: Bob Reynolds (5-5) L: Tom Murphy (7-7) S: Dave Johnson (2) | Second | 1 out |
| Tuesday, September 10 |
| » Lost to Brewers (68-75), 6-5 | County Stadium (3-6) | 74-67 | |
| » W: Tom Murphy (8-7) L: Grant Jackson (1-4) | Second | 2 out |
| » Major-league debuts: Sixto Lezcano (Brewers) |
| Wednesday, September 11 |
| » Defeated Yankees (76-66), 3-2 | Memorial Stadium (38-32) | 75-67 | |
| » W: Grant Jackson (2-4) L: Cecil Upshaw (1-6) | Second | 2 out |
| » Lost to Yankees (77-66), 5-1 | Memorial Stadium (38-33) | 75-68 | |
| » W: Larry Gura (3-0) L: Don Hood (1-1) | Second | 2 out |
| Thursday, September 12 |
| » Lost to Yankees (78-66), 3-0 | Memorial Stadium (38-34) | 75-69 | Lost 2 |
| » W: Mike Wallace (7-0) L: Jim Palmer (6-12) S: Dick Tidrow (1) | Third | 3 out |
| Friday, September 13 |
| » Defeated Indians (71-71), 3-2 | Memorial Stadium (39-34) | 76-69 | |
| » W: Mike Cuellar (19-10) L: Dick Bosman (6-4) | Third | 1½ out |
| » Defeated Indians (71-72), 8-6 | Memorial Stadium (40-34) | 77-69 | Won 2 |
| » W: Bob Reynolds (6-5) L: Tom Buskey (2-6) S: Grant Jackson (11) | Third | 1½ out |
| » Major-league debuts: Tim Nordbrook (Orioles) |
| Saturday, September 14 |
| » Defeated Indians (71-73), 7-1 | Memorial Stadium (41-34) | 78-69 | Won 3 |
| » W: Dave McNally (15-10) L: Fritz Peterson (9-12) | Second | 1½ out |
| Sunday, September 15 |
| » Lost to Indians (72-73), 1-0 | Memorial Stadium (41-35) | 78-70 | |
| » W: Gaylord Perry (20-10) L: Ross Grimsley (17-13) | Second | 2½ out |
| Tuesday, September 17 |
| » Defeated Yankees (80-68), 4-0 | Shea Stadium (4-3) | 79-70 | |
| » W: Jim Palmer (7-12) L: Doc Medich (18-14) | Second | 1½ out |
| Wednesday, September 18 |
| » Defeated Yankees (80-69), 10-4 | Shea Stadium (5-3) | 80-70 | Won 2 |
| » W: Mike Cuellar (20-10) L: Pat Dobson (16-15) | Second | ½ out |
| Thursday, September 19 |
| » Defeated Yankees (80-70), 7-0 | Shea Stadium (6-3) | 81-70 | Won 3 |
| » W: Dave McNally (16-10) L: Rudy May (6-4) | First | -- |
| Friday, September 20 |
| » Defeated Red Sox (77-73), 2-1 | Fenway Park (5-2) | 82-70 | Won 4 |
| » W: Ross Grimsley (18-13) L: Dick Drago (6-10) S: Grant Jackson (12) | First | -- |
| Saturday, September 21 |
| » Lost to Red Sox (78-73), 6-5 | Fenway Park (5-3) | 82-71 | |
| » W: Bill Lee (17-13) L: Dave Johnson (2-2) | Second | 1 out |
| Sunday, September 22 |
| » Defeated Red Sox (78-74), 7-2 | Fenway Park (6-3) | 83-71 | |
| » W: Mike Cuellar (21-10) L: Reggie Cleveland (11-14) | Second | 1 out |
| Tuesday, September 24 |
| » Defeated Tigers (71-83), 5-4 | Memorial Stadium (42-35) | 84-71 | Won 2 |
| » W: Bob Reynolds (7-5) L: John Hiller (17-12) | First | -- |
| Wednesday, September 25 |
| » Defeated Tigers (71-84), 5-4 | Memorial Stadium (43-35) | 85-71 | Won 3 |
| » W: Wayne Garland (5-5) L: Mickey Lolich (16-20) | First | -- |
| Friday, September 27 |
| » Defeated Brewers (75-83), 1-0 | Memorial Stadium (44-35) | 86-71 | Won 4 |
| » W: Grant Jackson (3-4) L: Tom Murphy (9-10) | First | -- |
| Future Oriole Radhames Dykhoff is born in Paradera, Aruba. |
| Saturday, September 28 |
| » Defeated Brewers (75-84), 7-1 | Memorial Stadium (45-35) | 87-71 | Won 5 |
| » W: Mike Cuellar (22-10) L: Bill Champion (11-4) | First | -- |
| Sunday, September 29 |
| » Defeated Brewers (75-85), 4-3 | Memorial Stadium (46-35) | 88-71 | Won 6 |
| » W: Grant Jackson (4-4) L: Jim Slaton (13-16) | First | -- |
| Monday, September 30 |
| » Defeated Tigers (72-88), 12-6 | Tiger Stadium (6-1) | 89-71 | Won 7 |
| » W: Grant Jackson (5-4) L: Mickey Lolich (16-21) | First | -- |
| Tuesday, October 1 |
| » Defeated Tigers (72-89), 7-6 | Tiger Stadium (7-1) | 90-71 | Won 8 |
| » W: Grant Jackson (6-4) L: John Hiller (17-14) S: Bob Reynolds (7) | First | -- |
| Wednesday, October 2 |
| » Defeated Tigers (72-90), 5-4 | Tiger Stadium (8-1) | 91-71 | Won 9 |
| » W: Doyle Alexander (6-9) L: Lerrin LaGrow (8-19) S: Don Hood (1) | First | -- |
Game information provided by Retrosheet (www.retrosheet.org) |