| Wednesday, January 2 |
| Former Cardinal Gordon Slade dies in Long Beach, CA at the age of 70. |
| Wednesday, February 27 |
| Future Cardinal Cliff Politte is born in St. Louis, MO. |
| Thursday, April 4 |
| » Major-league debuts: Jim Sundberg (Rangers) |
| Friday, April 5 |
| » Defeated Pirates (0-1), 6-5 | Busch Stadium II (1-0) | 1-0 | |
| » W: Al Hrabosky (1-0) L: Dave Giusti (0-1) | First | -- |
| Saturday, April 6 |
| » Defeated Pirates (0-2), 8-0 | Busch Stadium II (2-0) | 2-0 | Won 2 |
| » W: Sonny Siebert (1-0) L: Bob Moose (0-1) | First | -- |
| Wednesday, April 10 |
| » Lost to Mets (2-1), 3-2 | Shea Stadium (0-1) | 2-1 | |
| » W: Jerry Koosman (1-0) L: Jack Curtis (0-1) S: Bob Apodaca (1) | Third | ½ out |
| Thursday, April 11 |
| » Defeated Mets (2-2), 8-7 | Shea Stadium (1-1) | 3-1 | |
| » W: Mike Garman (1-0) L: Craig Swan (0-1) | Second | 1½ out |
| » Defeated Mets (2-3), 4-3 | Shea Stadium (2-1) | 4-1 | Won 2 |
| » W: Rich Folkers (1-0) L: Bob Apodaca (0-1) | Second | 1½ out |
| » Major-league debuts: Stan Papi (Cardinals) |
| Friday, April 12 |
| » Defeated Pirates (0-5), 7-6 | Three Rivers Stadium (1-0) | 5-1 | Won 3 |
| » W: Mike Garman (2-0) L: Bruce Kison (0-1) S: Rich Folkers (1) | Second | 2 out |
| Saturday, April 13 |
| » Defeated Pirates (0-6), 6-4 | Three Rivers Stadium (2-0) | 6-1 | Won 4 |
| » W: Lynn McGlothen (1-0) L: Jim Rooker (0-1) S: Pete Richert (1) | First | -- |
| Sunday, April 14 |
| » Lost to Pirates (1-6), 8-4 | Three Rivers Stadium (2-1) | 6-2 | |
| » W: Bob Moose (1-1) L: Mike Thompson (0-1) | First | -- |
| » Defeated Pirates (1-7), 6-5 | Three Rivers Stadium (3-1) | 7-2 | |
| » W: Jack Curtis (1-1) L: Ken Brett (0-1) S: Rich Folkers (2) | First | -- |
| Monday, April 15 |
| » Lost to Phillies (5-3), 3-2 | Veteran's Stadium (0-1) | 7-3 | |
| » W: Dick Ruthven (1-0) L: Alan Foster (0-1) S: Mac Scarce (1) | Second | 3 out |
| Tuesday, April 16 |
| » Lost to Phillies (6-3), 10-3 | Veteran's Stadium (0-2) | 7-4 | Lost 2 |
| » W: Steve Carlton (1-0) L: Bob Gibson (0-1) | Third | 3 out |
| Wednesday, April 17 |
| » Lost to Phillies (7-3), 12-5 | Veteran's Stadium (0-3) | 7-5 | Lost 3 |
| » W: George Culver (1-0) L: Sonny Siebert (1-1) | Third | 3 out |
| Thursday, April 18 |
| » Defeated Phillies (7-4), 6-2 | Veteran's Stadium (1-3) | 8-5 | |
| » W: Lynn McGlothen (2-0) L: Ron Schueler (0-2) | Fourth | 3 out |
| Friday, April 19 |
| » Lost to Expos (7-1), 5-4 | Busch Stadium II (2-1) | 8-6 | |
| » W: Ernie McAnally (1-1) L: Jack Curtis (1-2) S: Chuck Taylor (2) | Third | 3 out |
| Saturday, April 20 |
| » Defeated Expos (7-2), 10-4 | Busch Stadium II (3-1) | 9-6 | |
| » W: Alan Foster (1-1) L: Steve Renko (1-1) | Third | 3 out |
| Sunday, April 21 |
| » Lost to Expos (8-2), 9-5 | Busch Stadium II (3-2) | 9-7 | |
| » W: Steve Rogers (3-0) L: Bob Gibson (0-2) | Third | 3 out |
| Tuesday, April 23 |
| » Defeated Astros (10-8), 8-2 | Busch Stadium II (4-2) | 10-7 | |
| » W: Sonny Siebert (2-1) L: Doug Konieczny (0-2) | Third | 3 out |
| Wednesday, April 24 |
| » Lost to Astros (11-8), 9-4 | Busch Stadium II (4-3) | 10-8 | |
| » W: Dave Roberts (3-2) L: Lynn McGlothen (2-1) | Third | 3½ out |
| Friday, April 26 |
| » Lost to Reds (10-7), 4-3 | Busch Stadium II (4-4) | 10-9 | Lost 2 |
| » W: Don Gullett (2-1) L: Jack Curtis (1-3) S: Pedro Borbon (3) | Second | 3 out |
| Saturday, April 27 |
| » Defeated Reds (10-8), 4-3 | Busch Stadium II (5-4) | 11-9 | |
| » W: Orlando Pena (1-0) L: Pedro Borbon (1-1) | Second | 3 out |
| Sunday, April 28 |
| » Defeated Reds (10-9), 9-2 | Busch Stadium II (6-4) | 12-9 | Won 2 |
| » W: Bob Gibson (1-2) L: Clay Kirby (1-3) | Second | 3 out |
| Monday, April 29 |
| » Major-league debuts: Jim Todd (Cubs) |
| Tuesday, April 30 |
| » Defeated Braves (11-12), 7-2 | Busch Stadium II (7-4) | 13-9 | Won 3 |
| » W: Lynn McGlothen (3-1) L: Ron Reed (4-2) | First | -- |
| Wednesday, May 1 |
| » Lost to Braves (12-12), 6-5 | Busch Stadium II (7-5) | 13-10 | |
| » W: Carl Morton (3-2) L: Mike Garman (2-1) | First | -- |
| Friday, May 3 |
| » Lost to Astros (16-10), 4-1 | Astrodome (0-1) | 13-11 | Lost 2 |
| » W: Claude Osteen (4-2) L: Alan Foster (1-2) | First | -- |
| Saturday, May 4 |
| » Lost to Astros (17-10), 3-2 | Astrodome (0-2) | 13-12 | Lost 3 |
| » W: Dave Roberts (5-2) L: Sonny Siebert (2-2) S: Ken Forsch (3) | Second | 3½ out |
| Future Cardinal Miguel Cairo is born in Anaco, Venezuela. |
| Sunday, May 5 |
| » Defeated Astros (17-11), 3-1 | Astrodome (1-2) | 14-12 | |
| » W: Bob Gibson (2-2) L: Larry Dierker (2-1) | First | -- |
| Tuesday, May 7 |
| » Defeated Reds (12-12), 1-0 | Riverfront Stadium (1-0) | 15-12 | Won 2 |
| » W: Lynn McGlothen (4-1) L: Fred Norman (1-3) | First | -- |
| Wednesday, May 8 |
| » Defeated Reds (12-13), 2-0 | Riverfront Stadium (2-0) | 16-12 | Won 3 |
| » W: Jack Curtis (2-3) L: Don Gullett (2-3) | First | -- |
| Friday, May 10 |
| » Lost to Expos (11-11), 5-4 | Parc Jarry (0-1) | 16-13 | |
| » W: Steve Rogers (5-1) L: Alan Foster (1-3) | First | -- |
| Saturday, May 11 |
| » Lost to Expos (12-11), 3-1 | Parc Jarry (0-2) | 16-14 | Lost 2 |
| » W: Steve Renko (2-4) L: Sonny Siebert (2-3) | First | -- |
| Monday, May 13 |
| » Lost to Mets (14-18), 5-3 | Busch Stadium II (7-6) | 16-15 | Lost 3 |
| » W: Bob Apodaca (1-2) L: Bob Gibson (2-3) S: Harry Parker (1) | Third | 1 out |
| Wednesday, May 15 |
| » Defeated Mets (14-19), 10-1 | Busch Stadium II (8-6) | 17-15 | |
| » W: Lynn McGlothen (5-1) L: Jerry Koosman (4-1) | Second | 3½ out |
| Former Cardinal Lou North dies in Shelton, CT at the age of 83. |
| Thursday, May 16 |
| » Lost to Mets (15-19), 6-4 | Busch Stadium II (8-7) | 17-16 | |
| » W: George Stone (1-3) L: Jack Curtis (2-4) | Third | 3½ out |
| Friday, May 17 |
| » Defeated Cubs (13-18), 9-8 | Busch Stadium II (9-7) | 18-16 | |
| » W: Orlando Pena (2-0) L: Bill Bonham (2-7) | First | -- |
| Saturday, May 18 |
| » Defeated Cubs (13-19), 11-2 | Busch Stadium II (10-7) | 19-16 | Won 2 |
| » W: Sonny Siebert (3-3) L: Rick Reuschel (3-2) | First | -- |
| Sunday, May 19 |
| » Defeated Cubs (13-20), 6-5 | Busch Stadium II (11-7) | 20-16 | Won 3 |
| » W: Bob Gibson (3-3) L: Bill Bonham (2-8) S: Al Hrabosky (1) | First | -- |
| Monday, May 20 |
| » Lost to Phillies (21-17), 2-1 | Busch Stadium II (11-8) | 20-17 | |
| » W: Steve Carlton (5-3) L: Lynn McGlothen (5-2) | Third | ½ out |
| Tuesday, May 21 |
| » Lost to Phillies (22-17), 4-2 | Busch Stadium II (11-9) | 20-18 | Lost 2 |
| » W: Ed Farmer (2-0) L: Jack Curtis (2-5) S: Mac Scarce (3) | Third | 1½ out |
| Wednesday, May 22 |
| » Lost to Phillies (23-17), 7-1 | Busch Stadium II (11-10) | 20-19 | Lost 3 |
| » W: Ron Schueler (3-3) L: Alan Foster (1-4) | Third | 2½ out |
| Former Cardinal Ernie White dies in Augusta, GA at the age of 58. |
| Friday, May 24 |
| » Defeated Cubs (15-22), 1-0 | Wrigley Field (1-0) | 21-19 | |
| » W: Sonny Siebert (4-3) L: Rick Reuschel (3-3) | Third | 1½ out |
| Saturday, May 25 |
| » Lost to Cubs (16-22), 5-4 | Wrigley Field (1-1) | 21-20 | |
| » W: Bill Bonham (3-8) L: Bob Gibson (3-4) S: Dave LaRoche (1) | Third | 3 out |
| Sunday, May 26 |
| » Defeated Cubs (16-23), 7-1 | Wrigley Field (2-1) | 22-20 | |
| » W: Lynn McGlothen (6-2) L: Burt Hooton (2-4) | Third | 2 out |
| Monday, May 27 |
| » Defeated Dodgers (33-14), 7-2 | Busch Stadium II (12-10) | 23-20 | Won 2 |
| » W: Jack Curtis (3-5) L: Andy Messersmith (4-1) | Third | 1 out |
| Tuesday, May 28 |
| » Lost to Dodgers (34-14), 11-5 | Busch Stadium II (12-11) | 23-21 | |
| » W: Charlie Hough (5-1) L: Alan Foster (1-5) | Third | 1 out |
| Wednesday, May 29 |
| » Lost to Dodgers (35-14), 5-2 | Busch Stadium II (12-12) | 23-22 | Lost 2 |
| » W: Tommy John (8-1) L: Bob Gibson (3-5) S: Mike Marshall (7) | Third | 1 out |
| Friday, May 31 |
| » Defeated Padres (18-36), 5-0 | Busch Stadium II (13-12) | 24-22 | |
| » W: Sonny Siebert (5-3) L: Steve Arlin (1-7) | First | -- |
| Saturday, June 1 |
| » Defeated Padres (18-37), 3-0 | Busch Stadium II (14-12) | 25-22 | Won 2 |
| » W: Lynn McGlothen (7-2) L: Randy Jones (3-9) | First | -- |
| Sunday, June 2 |
| » Defeated Padres (18-38), 9-6 | Busch Stadium II (15-12) | 26-22 | Won 3 |
| » W: Orlando Pena (3-0) L: Vicente Romo (1-2) | First | -- |
| Tuesday, June 4 |
| » Lost to Giants (28-27), 5-3 | Candlestick Park (0-1) | 26-23 | |
| » W: Tom Bradley (6-4) L: Bob Gibson (3-6) S: Elias Sosa (1) | Second | 1½ out |
| Wednesday, June 5 |
| » Defeated Giants (28-28), 4-1 | Candlestick Park (1-1) | 27-23 | |
| » W: Sonny Siebert (6-3) L: Ron Bryant (2-5) S: Orlando Pena (1) | Second | 1½ out |
| Thursday, June 6 |
| » Lost to Giants (29-28), 9-5 | Candlestick Park (1-2) | 27-24 | |
| » W: Jim Barr (2-3) L: Lynn McGlothen (7-3) S: Elias Sosa (2) | Second | 1 out |
| Friday, June 7 |
| » Lost to Padres (21-39), 1-0 | San Diego/Jack Murphy Stadium (0-1) | 27-25 | Lost 2 |
| » W: Dave Freisleben (4-2) L: Jack Curtis (3-6) | Second | 1 out |
| Future Cardinal Chris Richard is born in San Diego, CA. |
| Saturday, June 8 |
| » Lost to Padres (22-39), 4-3 | San Diego/Jack Murphy Stadium (0-2) | 27-26 | Lost 3 |
| » W: Dan Spillner (2-1) L: Mike Thompson (0-2) S: Vicente Romo (7) | Second | 2 out |
| Sunday, June 9 |
| » Lost to Padres (23-39), 6-5 | San Diego/Jack Murphy Stadium (0-3) | 27-27 | Lost 4 |
| » W: Dave Tomlin (1-0) L: Mike Garman (2-2) S: Steve Arlin (1) | Second | 2 out |
| Future Cardinal Scarborough Green is born in Creve Coeur, MO. |
| Monday, June 10 |
| » Defeated Dodgers (42-17), 4-2 | Dodger Stadium (1-0) | 28-27 | |
| » W: Orlando Pena (4-0) L: Charlie Hough (6-2) | Second | 2 out |
| Tuesday, June 11 |
| » Defeated Dodgers (42-18), 1-0 | Dodger Stadium (2-0) | 29-27 | Won 2 |
| » W: Lynn McGlothen (8-3) L: Andy Messersmith (6-2) S: Al Hrabosky (2) | Second | 1 out |
| Wednesday, June 12 |
| » Defeated Dodgers (42-19), 6-3 | Dodger Stadium (3-0) | 30-27 | Won 3 |
| » W: Jack Curtis (4-6) L: Don Sutton (6-5) | Second | 1 out |
| Friday, June 14 |
| » Lost to Braves (34-26), 6-1 | Atlanta-Fulton County Stadium (0-1) | 30-28 | |
| » W: Roric Harrison (5-7) L: Bob Gibson (3-7) | Second | 1 out |
| Saturday, June 15 |
| » Lost to Braves (35-26), 7-1 | Atlanta-Fulton County Stadium (0-2) | 30-29 | Lost 2 |
| » W: Buzz Capra (6-2) L: Sonny Siebert (6-4) | Second | 2 out |
| Sunday, June 16 |
| » Defeated Braves (35-27), 6-3 | Atlanta-Fulton County Stadium (1-2) | 31-29 | |
| » W: Lynn McGlothen (9-3) L: Carl Morton (8-6) | Second | 1 out |
| Monday, June 17 |
| » Lost to Giants (32-35), 3-0 | Busch Stadium II (15-13) | 31-30 | |
| » W: Jim Barr (4-3) L: Jack Curtis (4-7) | Second | 2 out |
| Tuesday, June 18 |
| » Defeated Giants (32-36), 3-0 | Busch Stadium II (16-13) | 32-30 | |
| » W: Alan Foster (2-5) L: Ron Bryant (2-8) | Second | 1 out |
| Wednesday, June 19 |
| » Lost to Giants (33-36), 5-4 | Busch Stadium II (16-14) | 32-31 | |
| » W: John D'Acquisto (5-6) L: Bob Gibson (3-8) S: Steve Barber (1) | Third | 2 out |
| Friday, June 21 |
| » Defeated Expos (30-29), 5-1 | Busch Stadium II (17-14) | 33-31 | |
| » W: Sonny Siebert (7-4) L: Steve Renko (4-7) | Second | 1½ out |
| Saturday, June 22 |
| » Defeated Expos (30-30), 4-3 | Busch Stadium II (18-14) | 34-31 | Won 2 |
| » W: Lynn McGlothen (10-3) L: Steve Rogers (7-8) S: Mike Garman (1) | Second | 2 out |
| Sunday, June 23 |
| » Lost to Expos (31-30), 4-2 | Busch Stadium II (18-15) | 34-32 | |
| » W: Chuck Taylor (3-1) L: Al Hrabosky (1-1) | Second | 1½ out |
| Monday, June 24 |
| » Defeated Pirates (28-38), 3-1 | Busch Stadium II (19-15) | 35-32 | |
| » W: Alan Foster (3-5) L: Jerry Reuss (6-5) S: Mike Garman (2) | Second | 1 out |
| » Defeated Pirates (28-39), 4-0 | Busch Stadium II (20-15) | 36-32 | Won 2 |
| » W: Bob Gibson (4-8) L: Larry Demery (0-3) | Second | 1 out |
| Tuesday, June 25 |
| » Defeated Pirates (28-40), 8-7 | Busch Stadium II (21-15) | 37-32 | Won 3 |
| » W: Al Hrabosky (2-1) L: Daryl Patterson (1-1) S: Jack Curtis (1) | First | -- |
| Wednesday, June 26 |
| » Lost to Pirates (29-40), 7-2 | Busch Stadium II (21-16) | 37-33 | |
| » W: Jim Rooker (4-6) L: Sonny Siebert (7-5) | First | -- |
| Thursday, June 27 |
| » Defeated Mets (29-42), 6-1 | Shea Stadium (3-1) | 38-33 | |
| » W: Lynn McGlothen (11-3) L: Ray Sadecki (4-3) | First | -- |
| Saturday, June 29 |
| » Lost to Mets (30-42), 4-0 | Shea Stadium (3-2) | 38-34 | |
| » W: Jon Matlack (6-5) L: Jack Curtis (4-8) | First | -- |
| Sunday, June 30 |
| » Defeated Mets (30-43), 5-2 | Shea Stadium (4-2) | 39-34 | |
| » W: Alan Foster (4-5) L: Jerry Koosman (8-5) S: Al Hrabosky (3) | First | -- |
| » Defeated Mets (30-44), 5-3 | Shea Stadium (5-2) | 40-34 | Won 2 |
| » W: Orlando Pena (5-0) L: Tug McGraw (0-4) | First | -- |
| Tuesday, July 2 |
| » Lost to Cubs (32-42), 4-3 | Busch Stadium II (21-17) | 40-35 | |
| » W: Jim Todd (2-1) L: Sonny Siebert (7-6) S: Oscar Zamora (3) | First | -- |
| Wednesday, July 3 |
| » Defeated Cubs (32-43), 5-0 | Busch Stadium II (22-17) | 41-35 | |
| » W: Lynn McGlothen (12-3) L: Rick Reuschel (7-6) | First | -- |
| Thursday, July 4 |
| » Lost to Cubs (33-43), 3-2 | Busch Stadium II (22-18) | 41-36 | |
| » W: Steve Stone (3-2) L: Jack Curtis (4-9) S: Oscar Zamora (4) | First | -- |
| Friday, July 5 |
| » Defeated Reds (45-35), 3-2 | Riverfront Stadium (3-0) | 42-36 | |
| » W: Rich Folkers (2-0) L: Fred Norman (8-7) S: Mike Garman (3) | First | -- |
| Former Cardinal Duster Mails dies in San Francisco, CA at the age of 80. |
| Saturday, July 6 |
| » Defeated Reds (45-36), 3-1 | Riverfront Stadium (4-0) | 43-36 | Won 2 |
| » W: Bob Gibson (5-8) L: Clay Kirby (6-5) | First | -- |
| Sunday, July 7 |
| » Lost to Reds (46-36), 2-1 | Riverfront Stadium (4-1) | 43-37 | |
| » W: Tom Carroll (1-0) L: Bob Forsch (0-1) S: Will McEnaney (1) | First | -- |
| » Lost to Reds (47-36), 11-2 | Riverfront Stadium (4-2) | 43-38 | Lost 2 |
| » W: Don Gullett (9-6) L: Mike Thompson (0-3) | First | -- |
| » Major-league debuts: Tom Carroll (Reds) Bob Forsch (Cardinals) |
| Monday, July 8 |
| » Lost to Astros (44-41), 4-1 | Astrodome (1-3) | 43-39 | Lost 3 |
| » W: Tom Griffin (10-3) L: Lynn McGlothen (12-4) | First | -- |
| Tuesday, July 9 |
| » Lost to Astros (45-41), 5-2 | Astrodome (1-4) | 43-40 | Lost 4 |
| » W: Dave Roberts (6-7) L: Jack Curtis (4-10) | First | -- |
| Wednesday, July 10 |
| » Lost to Astros (46-41), 3-2 | Astrodome (1-5) | 43-41 | Lost 5 |
| » W: Mike Cosgrove (5-0) L: Orlando Pena (5-1) | First | -- |
| Friday, July 12 |
| » Lost to Braves (47-42), 7-3 | Busch Stadium II (22-19) | 43-42 | Lost 6 |
| » W: Joe Niekro (1-1) L: Bob Gibson (5-9) | First | -- |
| » Defeated Braves (47-43), 10-0 | Busch Stadium II (23-19) | 44-42 | |
| » W: Bob Forsch (1-1) L: Buzz Capra (9-4) | First | -- |
| Saturday, July 13 |
| » Lost to Braves (48-43), 8-1 | Busch Stadium II (23-20) | 44-43 | |
| » W: Ron Reed (6-4) L: Lynn McGlothen (12-5) | First | -- |
| Sunday, July 14 |
| » Lost to Braves (49-43), 7-0 | Busch Stadium II (23-21) | 44-44 | Lost 2 |
| » W: Phil Niekro (9-8) L: Ray Bare (0-1) | Second | 1½ out |
| Monday, July 15 |
| » Lost to Reds (54-38), 3-0 | Busch Stadium II (23-22) | 44-45 | Lost 3 |
| » W: Clay Kirby (7-5) L: Alan Foster (4-6) | Second | 2 out |
| Tuesday, July 16 |
| » Lost to Reds (55-38), 12-7 | Busch Stadium II (23-23) | 44-46 | Lost 4 |
| » W: Don Gullett (11-6) L: Bob Forsch (1-2) | Third | 2 out |
| Wednesday, July 17 |
| » Lost to Reds (56-38), 6-4 | Busch Stadium II (23-24) | 44-47 | Lost 5 |
| » W: Will McEnaney (1-0) L: Rich Folkers (2-1) S: Pedro Borbon (12) | Third | 2 out |
| Former Cardinal Dizzy Dean dies in Reno, NV at the age of 65. |
| Thursday, July 18 |
| » Lost to Astros (50-44), 8-2 | Busch Stadium II (23-25) | 44-48 | Lost 6 |
| » W: Claude Osteen (9-7) L: Lynn McGlothen (12-6) | Third | 3 out |
| Friday, July 19 |
| » Lost to Astros (51-44), 5-1 | Busch Stadium II (23-26) | 44-49 | Lost 7 |
| » W: Tom Griffin (11-3) L: Ray Bare (0-2) | Third | 3 out |
| Saturday, July 20 |
| » Defeated Astros (51-45), 6-5 | Busch Stadium II (24-26) | 45-49 | |
| » W: Al Hrabosky (3-1) L: Mike Cosgrove (5-1) | Third | 3 out |
| Sunday, July 21 |
| » Defeated Astros (51-46), 9-1 | Busch Stadium II (25-26) | 46-49 | Won 2 |
| » W: Bob Forsch (2-2) L: Larry Dierker (6-6) | Third | 3 out |
| Thursday, July 25 |
| » Defeated Mets (40-53), 4-3 | Busch Stadium II (26-26) | 47-49 | Won 3 |
| » W: Rich Folkers (3-1) L: Jack Aker (1-2) | Second | 2½ out |
| » Defeated Mets (40-54), 4-1 | Busch Stadium II (27-26) | 48-49 | Won 4 |
| » W: Alan Foster (5-6) L: Jon Matlack (9-7) | Second | 2½ out |
| Friday, July 26 |
| » Lost to Mets (41-54), 3-0 | Busch Stadium II (27-27) | 48-50 | |
| » W: Tom Seaver (7-6) L: Lynn McGlothen (12-7) | Second | 2½ out |
| Saturday, July 27 |
| » Defeated Cubs (42-54), 3-2 | Wrigley Field (3-1) | 49-50 | |
| » W: Bob Forsch (3-2) L: Bill Bonham (9-12) | Second | 3 out |
| Sunday, July 28 |
| » Defeated Cubs (42-55), 5-4 | Wrigley Field (4-1) | 50-50 | Won 2 |
| » W: Al Hrabosky (4-1) L: Ken Frailing (5-8) S: Mike Garman (4) | Second | 2 out |
| Monday, July 29 |
| » Defeated Cubs (42-56), 11-4 | Wrigley Field (5-1) | 51-50 | Won 3 |
| » W: Jack Curtis (5-10) L: Burt Hooton (3-10) | Second | 2 out |
| Tuesday, July 30 |
| » Defeated Phillies (53-49), 4-3 | Veteran's Stadium (2-3) | 52-50 | Won 4 |
| » W: Al Hrabosky (5-1) L: Jesus Hernaiz (2-2) | Second | 1 out |
| Wednesday, July 31 |
| » Defeated Phillies (53-50), 9-8 | Veteran's Stadium (3-3) | 53-50 | Won 5 |
| » W: Bob Gibson (6-9) L: Dick Ruthven (4-8) S: Al Hrabosky (4) | First | -- |
| Thursday, August 1 |
| » Defeated Pirates (50-55), 5-2 | Three Rivers Stadium (4-1) | 54-50 | Won 6 |
| » W: Rich Folkers (4-1) L: Dave Giusti (5-4) | First | -- |
| Friday, August 2 |
| » Lost to Pirates (51-55), 3-2 | Three Rivers Stadium (4-2) | 54-51 | |
| » W: Ramon Hernandez (1-1) L: Orlando Pena (5-2) | First | -- |
| Saturday, August 3 |
| » Defeated Phillies (54-52), 4-3 | Busch Stadium II (28-27) | 55-51 | |
| » W: Mike Garman (3-2) L: Jim Lonborg (12-11) | First | -- |
| Sunday, August 4 |
| » Lost to Phillies (55-52), 6-1 | Busch Stadium II (28-28) | 55-52 | |
| » W: Ron Schueler (6-11) L: Alan Foster (5-7) | First | -- |
| » Defeated Phillies (55-53), 11-0 | Busch Stadium II (29-28) | 56-52 | |
| » W: Jack Curtis (6-10) L: Dick Ruthven (4-9) | First | -- |
| Monday, August 5 |
| » Defeated Phillies (55-54), 3-2 | Busch Stadium II (30-28) | 57-52 | Won 2 |
| » W: Mike Garman (4-2) L: Pete Richert (1-1) | First | -- |
| Tuesday, August 6 |
| » Defeated Expos (50-57), 5-4 | Parc Jarry (1-2) | 58-52 | Won 3 |
| » W: Lynn McGlothen (13-7) L: Mike Torrez (9-8) S: Al Hrabosky (5) | First | -- |
| » Defeated Expos (50-58), 9-4 | Parc Jarry (2-2) | 59-52 | Won 4 |
| » W: Rich Folkers (5-1) L: Steve Rogers (11-14) | First | -- |
| Wednesday, August 7 |
| » Lost to Expos (51-58), 7-5 | Parc Jarry (2-3) | 59-53 | |
| » W: Steve Renko (8-11) L: Bob Forsch (3-3) | First | -- |
| Thursday, August 8 |
| » Lost to Expos (52-58), 3-2 | Parc Jarry (2-4) | 59-54 | Lost 2 |
| » W: Don Carrithers (2-1) L: Jack Curtis (6-11) | First | -- |
| Former Cardinal Howie Pollet dies in Houston, TX at the age of 54. |
| Friday, August 9 |
| » Defeated Dodgers (73-40), 5-3 | Busch Stadium II (31-28) | 60-54 | |
| » W: Alan Foster (6-7) L: Geoff Zahn (2-2) S: Al Hrabosky (6) | First | -- |
| Future Cardinal Matt Morris is born in Middletown, NY. |
| Saturday, August 10 |
| » Lost to Dodgers (74-40), 6-2 | Busch Stadium II (31-29) | 60-55 | |
| » W: Doug Rau (12-6) L: Bob Gibson (6-10) S: Mike Marshall (17) | First | -- |
| Sunday, August 11 |
| » Lost to Dodgers (75-40), 3-1 | Busch Stadium II (31-30) | 60-56 | Lost 2 |
| » W: Don Sutton (10-8) L: Lynn McGlothen (13-8) | First | -- |
| Monday, August 12 |
| » Defeated Padres (46-71), 6-5 | Busch Stadium II (32-30) | 61-56 | |
| » W: Al Hrabosky (6-1) L: Bill Laxton (0-1) | First | -- |
| Tuesday, August 13 |
| » Lost to Padres (47-71), 2-1 | Busch Stadium II (32-31) | 61-57 | |
| » W: Lowell Palmer (2-4) L: Sonny Siebert (7-7) | First | -- |
| Wednesday, August 14 |
| » Defeated Padres (47-72), 5-1 | Busch Stadium II (33-31) | 62-57 | |
| » W: Alan Foster (7-7) L: Randy Jones (7-17) | First | -- |
| Friday, August 16 |
| » Defeated Giants (54-66), 2-1 | Busch Stadium II (34-31) | 63-57 | Won 2 |
| » W: Bob Gibson (7-10) L: John D'Acquisto (9-11) | First | -- |
| Saturday, August 17 |
| » Defeated Giants (54-67), 5-3 | Busch Stadium II (35-31) | 64-57 | Won 3 |
| » W: Mike Garman (5-2) L: Randy Moffitt (4-6) | First | -- |
| Sunday, August 18 |
| » Defeated Giants (54-68), 4-1 | Busch Stadium II (36-31) | 65-57 | Won 4 |
| » W: Jack Curtis (7-11) L: Tom Bradley (7-11) | First | -- |
| Monday, August 19 |
| » Lost to Braves (65-56), 11-6 | Atlanta-Fulton County Stadium (1-3) | 65-58 | |
| » W: Joe Niekro (2-2) L: Claude Osteen (9-10) S: Max Leon (2) | First | -- |
| Tuesday, August 20 |
| » Lost to Braves (66-56), 8-6 | Atlanta-Fulton County Stadium (1-4) | 65-59 | Lost 2 |
| » W: Phil Niekro (14-10) L: Alan Foster (7-8) S: Tom House (8) | First | -- |
| Wednesday, August 21 |
| » Lost to Braves (67-56), 5-4 | Atlanta-Fulton County Stadium (1-5) | 65-60 | Lost 3 |
| » W: Buzz Capra (11-6) L: Bob Gibson (7-11) | First | -- |
| Friday, August 23 |
| » Defeated Dodgers (78-47), 2-1 | Dodger Stadium (4-0) | 66-60 | |
| » W: Lynn McGlothen (14-8) L: Mike Marshall (12-9) S: Mike Garman (5) | First | -- |
| Saturday, August 24 |
| » Lost to Dodgers (79-47), 3-0 | Dodger Stadium (4-1) | 66-61 | |
| » W: Don Sutton (12-9) L: Jack Curtis (7-12) | First | -- |
| Sunday, August 25 |
| » Lost to Dodgers (80-47), 9-3 | Dodger Stadium (4-2) | 66-62 | Lost 2 |
| » W: Andy Messersmith (15-5) L: Alan Foster (7-9) S: Mike Marshall (19) | Second | ½ out |
| Tuesday, August 27 |
| » Lost to Padres (50-79), 3-1 | San Diego/Jack Murphy Stadium (0-4) | 66-63 | Lost 3 |
| » W: Dan Spillner (6-8) L: Bob Gibson (7-12) | Second | 1½ out |
| Wednesday, August 28 |
| » Defeated Padres (50-80), 5-1 | San Diego/Jack Murphy Stadium (1-4) | 67-63 | |
| » W: Lynn McGlothen (15-8) L: Bill Greif (6-16) | Second | 1½ out |
| Thursday, August 29 |
| » Defeated Padres (50-81), 3-1 | San Diego/Jack Murphy Stadium (2-4) | 68-63 | Won 2 |
| » W: Jack Curtis (8-12) L: Larry Hardy (7-4) | Second | ½ out |
| Friday, August 30 |
| » Lost to Giants (59-73), 8-2 | Candlestick Park (1-3) | 68-64 | |
| » W: Mike Caldwell (13-3) L: Sonny Siebert (7-8) | Second | 1½ out |
| » Major-league debuts: Keith Hernandez (Cardinals) |
| Saturday, August 31 |
| » Lost to Giants (60-73), 3-2 | Candlestick Park (1-4) | 68-65 | Lost 2 |
| » W: John D'Acquisto (10-12) L: Bob Forsch (3-4) S: John Morris (1) | Second | 2½ out |
| Sunday, September 1 |
| » Defeated Giants (60-74), 8-1 | Candlestick Park (2-4) | 69-65 | |
| » W: Bob Gibson (8-12) L: Ed Halicki (1-8) | Second | 1½ out |
| Tuesday, September 3 |
| » Defeated Expos (61-71), 5-1 | Busch Stadium II (37-31) | 70-65 | Won 2 |
| » W: Lynn McGlothen (16-8) L: Tom Walker (2-5) | Second | 2 out |
| » Defeated Expos (61-72), 8-4 | Busch Stadium II (38-31) | 71-65 | Won 3 |
| » W: Mike Garman (6-2) L: Steve Rogers (12-19) | Second | 2 out |
| Wednesday, September 4 |
| » Defeated Expos (61-73), 5-4 | Busch Stadium II (39-31) | 72-65 | Won 4 |
| » W: Rich Folkers (6-1) L: Chuck Taylor (6-2) S: Al Hrabosky (7) | Second | 1½ out |
| » Major-league debuts: Larry Herndon (Cardinals) |
| Friday, September 6 |
| » Defeated Mets (63-72), 3-0 | Busch Stadium II (40-31) | 73-65 | Won 5 |
| » W: Bob Forsch (4-4) L: Jerry Koosman (13-9) | Second | 1½ out |
| Saturday, September 7 |
| » Defeated Mets (63-73), 2-1 | Busch Stadium II (41-31) | 74-65 | Won 6 |
| » W: Bob Gibson (9-12) L: Jon Matlack (12-11) | Second | 1½ out |
| Sunday, September 8 |
| » Lost to Mets (64-73), 5-3 | Busch Stadium II (41-32) | 74-66 | |
| » W: Tom Seaver (10-8) L: Lynn McGlothen (16-9) | Second | 2½ out |
| Monday, September 9 |
| » Lost to Phillies (70-71), 2-0 | Busch Stadium II (41-33) | 74-67 | Lost 2 |
| » W: Jim Lonborg (15-11) L: Jack Curtis (8-13) | Second | 2½ out |
| Tuesday, September 10 |
| » Lost to Phillies (71-71), 8-2 | Busch Stadium II (41-34) | 74-68 | Lost 3 |
| » W: Dick Ruthven (9-11) L: Alan Foster (7-10) | Second | 3½ out |
| » Major-league debuts: Jerry Mumphrey (Cardinals) |
| Wednesday, September 11 |
| » Defeated Mets (65-75), 4-3 | Shea Stadium (6-2) | 75-68 | |
| » W: Sonny Siebert (8-8) L: Hank Webb (0-1) | Second | 2½ out |
| » Major-league debuts: Bruce Boisclair (Mets) |
| Thursday, September 12 |
| » Defeated Mets (65-76), 12-5 | Shea Stadium (7-2) | 76-68 | Won 2 |
| » W: Bob Gibson (10-12) L: Jon Matlack (12-12) S: Al Hrabosky (8) | Second | 1½ out |
| » Major-league debuts: John Denny (Cardinals) |
| Friday, September 13 |
| » Defeated Phillies (73-72), 7-3 | Veteran's Stadium (4-3) | 77-68 | Won 3 |
| » W: Ray Bare (1-2) L: Jesus Hernaiz (2-3) | Second | ½ out |
| Saturday, September 14 |
| » Defeated Phillies (73-73), 9-2 | Veteran's Stadium (5-3) | 78-68 | Won 4 |
| » W: Jack Curtis (9-13) L: Dick Ruthven (9-12) | First | -- |
| Sunday, September 15 |
| » Defeated Phillies (73-74), 3-1 | Veteran's Stadium (6-3) | 79-68 | Won 5 |
| » W: Bob Forsch (5-4) L: Steve Carlton (14-12) S: Al Hrabosky (9) | First | -- |
| Tuesday, September 17 |
| » Defeated |