| Tuesday, March 6 |
| Future Tiger Roberto Duran is born in Moca, D.R. |
| Thursday, March 8 |
| Future Tiger Justin Thompson is born in San Antonio, TX. |
| Friday, March 9 |
| Future Tiger C.J. Nitkowski is born in Suffern, NY. |
| Thursday, April 5 |
| » Major-league debuts: Gene Locklear (Reds) |
| Saturday, April 7 |
| » Lost to Indians (1-0), 2-1 | Cleveland Stadium (0-1) | 0-1 | |
| » Starters: Mickey Lolich vs Gaylord Perry | Third | 1½ out |
| Sunday, April 8 |
| » Defeated Indians (1-1), 4-0 | Cleveland Stadium (1-1) | 1-1 | |
| » Starters: Joe Coleman vs Dick Tidrow | Third | 1½ out |
| Wednesday, April 11 |
| » Lost to Orioles (3-0), 3-1 | Tiger Stadium (0-1) | 1-2 | |
| » Starters: Jim Palmer vs Woodie Fryman | Third | 2 out |
| Thursday, April 12 |
| » Lost to Orioles (4-0), 1-0 | Tiger Stadium (0-2) | 1-3 | Lost 2 |
| » Starters: Dave McNally vs Mickey Lolich | Fifth | 3 out |
| Friday, April 13 |
| » Defeated Indians (2-4), 4-3 | Tiger Stadium (1-2) | 2-3 | |
| » Starters: Brent Strom vs Joe Coleman | Third | 2 out |
| Saturday, April 14 |
| » Defeated Indians (2-5), 8-2 | Tiger Stadium (2-2) | 3-3 | Won 2 |
| » Starters: Steve Dunning vs Jim Perry | Third | 2 out |
| Sunday, April 15 |
| » Lost to Indians (3-5), 7-0 | Tiger Stadium (2-3) | 3-4 | |
| » Starters: Gaylord Perry vs Tom Timmermann | Third | 2 out |
| » Major-league debuts: Dave Lemanczyk (Tigers) |
| Monday, April 16 |
| » Defeated Red Sox (4-2), 9-7 | Fenway Park (1-0) | 4-4 | |
| » Starters: Mickey Lolich vs Marty Pattin | Third | 2 out |
| Tuesday, April 17 |
| » Defeated Red Sox (4-3), 6-3 | Fenway Park (2-0) | 5-4 | Won 2 |
| » Starters: Joe Coleman vs Lynn McGlothen | Third | 2 out |
| Wednesday, April 18 |
| » Defeated Red Sox (4-4), 7-1 | Fenway Park (3-0) | 6-4 | Won 3 |
| » Starters: Jim Perry vs Luis Tiant | Second | 1 out |
| Thursday, April 19 |
| » Defeated Red Sox (4-5), 11-7 | Fenway Park (4-0) | 7-4 | Won 4 |
| » Starters: Woodie Fryman vs John Curtis | First | -- |
| Friday, April 20 |
| » Lost to Orioles (8-4), 6-5 | Memorial Stadium (0-1) | 7-5 | |
| » Starters: Mickey Lolich vs Doyle Alexander | Second | 1 out |
| Saturday, April 21 |
| » Defeated Orioles (8-5), 3-1 | Memorial Stadium (1-1) | 8-5 | |
| » Starters: Joe Coleman vs Dave McNally | First | -- |
| Sunday, April 22 |
| » Lost to Orioles (9-5), 5-3 | Memorial Stadium (1-2) | 8-6 | |
| » Starters: Jim Perry vs Mike Cuellar | Second | 1 out |
| Tuesday, April 24 |
| » Lost to Rangers (3-8), 2-1 | Arlington Stadium (0-1) | 8-7 | Lost 2 |
| » Starters: Mickey Lolich vs Mike Paul | Third | 1 out |
| Wednesday, April 25 |
| » Lost to Rangers (4-8), 4-1 | Arlington Stadium (0-2) | 8-8 | Lost 3 |
| » Starters: Joe Coleman vs Rich Hand | Third | 1 out |
| Thursday, April 26 |
| » Defeated Rangers (4-9), 3-2 | Arlington Stadium (1-2) | 9-8 | |
| » Starters: Woodie Fryman vs Pete Broberg | Third | ½ out |
| Friday, April 27 |
| » Lost to Royals (12-7), 3-0 | Tiger Stadium (2-4) | 9-9 | |
| » Starters: Steve Busby vs Jim Perry | Third | ½ out |
| Saturday, April 28 |
| » Lost to Royals (13-7), 7-4 | Tiger Stadium (2-5) | 9-10 | Lost 2 |
| » Starters: Paul Splittorff vs Mickey Lolich | Third | 1½ out |
| Sunday, April 29 |
| » Defeated Royals (13-8), 6-1 | Tiger Stadium (3-5) | 10-10 | |
| » Starters: Wayne Simpson vs Joe Coleman | Third | ½ out |
| » Major-league debuts: Doug Bird (Royals) |
| Tuesday, May 1 |
| » Lost to Angels (10-8), 6-2 | Tiger Stadium (3-6) | 10-11 | |
| » Starters: Bill Singer vs Woodie Fryman | Third | 1 out |
| Wednesday, May 2 |
| » Lost to Angels (11-8), 5-3 | Tiger Stadium (3-7) | 10-12 | Lost 2 |
| » Starters: Nolan Ryan vs Mickey Lolich | Third | 1 out |
| Friday, May 4 |
| » Defeated Rangers (7-12), 5-1 | Tiger Stadium (4-7) | 11-12 | |
| » Starters: Dick Bosman vs Jim Perry | First | -- |
| Saturday, May 5 |
| » Defeated Rangers (7-13), 2-0 | Tiger Stadium (5-7) | 12-12 | Won 2 |
| » Starters: Mike Paul vs Joe Coleman | First | -- |
| Sunday, May 6 |
| » Lost to Rangers (8-13), 7-2 | Tiger Stadium (5-8) | 12-13 | |
| » Starters: Rich Hand vs Mickey Lolich | First | -- |
| Tuesday, May 8 |
| » Lost to Royals (17-10), 7-2 | Royals Stadium (0-1) | 12-14 | Lost 2 |
| » Starters: Woodie Fryman vs Paul Splittorff | Second | ½ out |
| Wednesday, May 9 |
| » Defeated Royals (17-11), 4-1 | Royals Stadium (1-1) | 13-14 | |
| » Starters: Jim Perry vs Steve Busby | First | -- |
| Thursday, May 10 |
| » Lost to Royals (18-11), 8-2 | Royals Stadium (1-2) | 13-15 | |
| » Starters: Joe Coleman vs Dick Drago | Second | 1½ out |
| Friday, May 11 |
| » Defeated Brewers (12-14), 6-5 | Tiger Stadium (6-8) | 14-15 | |
| » Starters: Jerry Bell vs Mickey Lolich | First | -- |
| Saturday, May 12 |
| » Lost to Brewers (13-14), 6-2 | Tiger Stadium (6-9) | 14-16 | |
| » Starters: Jim Slaton vs Woodie Fryman | Second | 1½ out |
| Sunday, May 13 |
| » Lost to Brewers (14-14), 6-5 | Tiger Stadium (6-10) | 14-17 | Lost 2 |
| » Starters: Jim Colborn vs Jim Perry | Fourth | 1½ out |
| Monday, May 14 |
| » Defeated Yankees (14-17), 8-0 | Yankee Stadium (1-0) | 15-17 | |
| » Starters: Joe Coleman vs Fritz Peterson | Second | 1½ out |
| Wednesday, May 16 |
| » Defeated Red Sox (14-16), 6-5 | Tiger Stadium (7-10) | 16-17 | Won 2 |
| » Starters: Luis Tiant vs Mickey Lolich | First | -- |
| Thursday, May 17 |
| » Defeated Red Sox (14-17), 1-0 | Tiger Stadium (8-10) | 17-17 | Won 3 |
| » Starters: John Curtis vs Jim Perry | First | -- |
| Friday, May 18 |
| » Defeated Red Sox (14-18), 5-4 | Tiger Stadium (9-10) | 18-17 | Won 4 |
| » Starters: Marty Pattin vs Woodie Fryman | First | -- |
| Saturday, May 19 |
| » Defeated Brewers (16-18), 4-2 | County Stadium (1-0) | 19-17 | Won 5 |
| » Starters: Joe Coleman vs Jerry Bell | First | -- |
| Sunday, May 20 |
| » Lost to Brewers (17-18), 1-0 | County Stadium (1-1) | 19-18 | |
| » Starters: Mickey Lolich vs Bill Parsons | First | -- |
| » Defeated Brewers (17-19), 5-3 | County Stadium (2-1) | 20-18 | |
| » Starters: Jim Perry vs Gary Ryerson | First | -- |
| Monday, May 21 |
| Former Tiger Herm Wehmeier dies in Dallas, TX at the age of 47. |
| Tuesday, May 22 |
| » Lost to Yankees (19-20), 7-2 | Tiger Stadium (9-11) | 20-19 | |
| » Starters: Mel Stottlemyre vs Woodie Fryman | First | -- |
| Wednesday, May 23 |
| » Lost to Yankees (20-20), 6-5 | Tiger Stadium (9-12) | 20-20 | Lost 2 |
| » Starters: Fritz Peterson vs Joe Coleman | First | -- |
| Thursday, May 24 |
| » Defeated Yankees (20-21), 4-0 | Tiger Stadium (10-12) | 21-20 | |
| » Starters: Doc Medich vs Mickey Lolich | First | -- |
| Friday, May 25 |
| » Defeated Athletics (23-20), 1-0 | Tiger Stadium (11-12) | 22-20 | Won 2 |
| » Starters: Catfish Hunter vs Jim Perry | First | -- |
| Saturday, May 26 |
| » Defeated Athletics (23-21), 8-5 | Tiger Stadium (12-12) | 23-20 | Won 3 |
| » Starters: Ken Holtzman vs Woodie Fryman | First | -- |
| Monday, May 28 |
| » Defeated Athletics (23-22), 4-3 | Tiger Stadium (13-12) | 24-20 | Won 4 |
| » Starters: Blue Moon Odom vs Joe Coleman | First | -- |
| Tuesday, May 29 |
| Future Tiger Trever Miller is born in Louisville, KY. |
| Wednesday, May 30 |
| » Defeated White Sox (26-15), 8-3 | Comiskey Park I (1-0) | 25-20 | Won 5 |
| » Starters: Mickey Lolich vs Stan Bahnsen | First | -- |
| Thursday, May 31 |
| » Lost to White Sox (27-15), 10-2 | Comiskey Park I (1-1) | 25-21 | |
| » Starters: Jim Perry vs Eddie Fisher | First | -- |
| » Major-league debuts: Brian Downing (White Sox) |
| Friday, June 1 |
| » Defeated Twins (25-20), 8-3 | Metropolitan Stadium (1-0) | 26-21 | |
| » Starters: Joe Coleman vs Jim Kaat | First | -- |
| Saturday, June 2 |
| » Lost to Twins (26-20), 3-2 | Metropolitan Stadium (1-1) | 26-22 | |
| » Starters: Woodie Fryman vs Bert Blyleven | First | -- |
| Sunday, June 3 |
| » Defeated Twins (26-21), 8-2 | Metropolitan Stadium (2-1) | 27-22 | |
| » Starters: Mickey Lolich vs Bill Hands | First | -- |
| Tuesday, June 5 |
| » Defeated Angels (25-23), 5-2 | Anaheim Stadium (1-0) | 28-22 | Won 2 |
| » Starters: Jim Perry vs Rich Hand | First | -- |
| Wednesday, June 6 |
| » Lost to Angels (26-23), 7-4 | Anaheim Stadium (1-1) | 28-23 | |
| » Starters: Joe Coleman vs Bill Singer | First | -- |
| Thursday, June 7 |
| » Lost to Angels (27-23), 3-0 | Anaheim Stadium (1-2) | 28-24 | Lost 2 |
| » Starters: Woodie Fryman vs Nolan Ryan | First | -- |
| Friday, June 8 |
| » Defeated Athletics (27-28), 4-1 | Oakland-Alameda County Stadium (1-0) | 29-24 | |
| » Starters: Mickey Lolich vs Vida Blue | First | -- |
| Saturday, June 9 |
| » Lost to Athletics (28-28), 4-0 | Oakland-Alameda County Stadium (1-1) | 29-25 | |
| » Starters: Jim Perry vs Ken Holtzman | Second | ½ out |
| Sunday, June 10 |
| » Lost to Athletics (29-28), 5-0 | Oakland-Alameda County Stadium (1-2) | 29-26 | Lost 2 |
| » Starters: Joe Coleman vs Catfish Hunter | Second | ½ out |
| Tuesday, June 12 |
| » Defeated White Sox (31-22), 6-5 | Tiger Stadium (14-12) | 30-26 | |
| » Starters: Wilbur Wood vs Woodie Fryman | First | -- |
| Wednesday, June 13 |
| » Lost to White Sox (32-22), 10-2 | Tiger Stadium (14-13) | 30-27 | |
| » Starters: Stan Bahnsen vs Mickey Lolich | Second | ½ out |
| Friday, June 15 |
| » Lost to Twins (31-25), 13-6 | Tiger Stadium (14-14) | 30-28 | Lost 2 |
| » Starters: Dick Woodson vs Jim Perry | Fourth | 1 out |
| Saturday, June 16 |
| » Lost to Twins (32-25), 5-0 | Tiger Stadium (14-15) | 30-29 | Lost 3 |
| » Starters: Bert Blyleven vs Joe Coleman | Fourth | 2 out |
| Sunday, June 17 |
| » Defeated Twins (32-26), 6-0 | Tiger Stadium (15-15) | 31-29 | |
| » Starters: Joe Decker vs Mickey Lolich | Fourth | 2 out |
| Monday, June 18 |
| » Defeated Indians (22-41), 5-1 | Cleveland Stadium (2-1) | 32-29 | Won 2 |
| » Starters: Jim Perry vs Brent Strom | Third | 2 out |
| Tuesday, June 19 |
| » Lost to Indians (23-41), 8-7 | Cleveland Stadium (2-2) | 32-30 | |
| » Starters: Woodie Fryman vs Dick Tidrow | Fourth | 1½ out |
| Wednesday, June 20 |
| » Lost to Indians (24-41), 7-6 | Cleveland Stadium (2-3) | 32-31 | Lost 2 |
| » Starters: Joe Coleman vs Dick Bosman | Fourth | 2 out |
| Thursday, June 21 |
| » Lost to Yankees (36-30), 5-1 | Yankee Stadium (1-1) | 32-32 | Lost 3 |
| » Starters: Mickey Lolich vs Pat Dobson | Fourth | 3 out |
| Friday, June 22 |
| » Lost to Yankees (37-30), 5-4 | Yankee Stadium (1-2) | 32-33 | Lost 4 |
| » Starters: Jim Perry vs Fritz Peterson | Fifth | 4 out |
| Saturday, June 23 |
| » Lost to Yankees (38-30), 3-2 | Yankee Stadium (1-3) | 32-34 | Lost 5 |
| » Starters: Woodie Fryman vs Sam McDowell | Fifth | 5 out |
| Sunday, June 24 |
| » Lost to Yankees (39-30), 3-2 | Yankee Stadium (1-4) | 32-35 | Lost 6 |
| » Starters: Joe Coleman vs Steve Kline | Fifth | 7 out |
| » Lost to Yankees (40-30), 2-1 | Yankee Stadium (1-5) | 32-36 | Lost 7 |
| » Starters: Mickey Lolich vs Doc Medich | Fifth | 7 out |
| Monday, June 25 |
| » Lost to Red Sox (34-33), 2-1 | Fenway Park (4-1) | 32-37 | Lost 8 |
| » Starters: Jim Perry vs Bill Lee | Fifth | 7 out |
| Tuesday, June 26 |
| » Defeated Red Sox (34-34), 4-1 | Fenway Park (5-1) | 33-37 | |
| » Starters: Mike Strahler vs Luis Tiant | Fifth | 7 out |
| Wednesday, June 27 |
| » Defeated Brewers (37-34), 6-3 | Tiger Stadium (16-15) | 34-37 | Won 2 |
| » Starters: Jim Slaton vs Joe Coleman | Fifth | 5½ out |
| » Defeated Brewers (37-35), 5-4 | Tiger Stadium (17-15) | 35-37 | Won 3 |
| » Starters: Eduardo Rodriguez vs Woodie Fryman | Fifth | 5½ out |
| Thursday, June 28 |
| » Defeated Brewers (37-36), 8-6 | Tiger Stadium (18-15) | 36-37 | Won 4 |
| » Starters: Chris Short vs Mickey Lolich | Fifth | 4½ out |
| Friday, June 29 |
| » Lost to Orioles (37-30), 9-2 | Tiger Stadium (18-16) | 36-38 | |
| » Starters: Doyle Alexander vs Jim Perry | Fifth | 5½ out |
| Saturday, June 30 |
| » Defeated Orioles (37-31), 4-1 | Tiger Stadium (19-16) | 37-38 | |
| » Starters: Mike Cuellar vs Mike Strahler | Fifth | 5½ out |
| Sunday, July 1 |
| » Defeated Orioles (37-32), 5-3 | Tiger Stadium (20-16) | 38-38 | Won 2 |
| » Starters: Jim Palmer vs Joe Coleman | Fourth | 5½ out |
| » Defeated Orioles (37-33), 1-0 | Tiger Stadium (21-16) | 39-38 | Won 3 |
| » Starters: Dave McNally vs Mickey Lolich | Fourth | 5½ out |
| Monday, July 2 |
| » Defeated Indians (27-51), 4-3 | Cleveland Stadium (3-3) | 40-38 | Won 4 |
| » Starters: Woodie Fryman vs Dick Tidrow | Third | 4½ out |
| Tuesday, July 3 |
| » Defeated Indians (27-52), 5-4 | Cleveland Stadium (4-3) | 41-38 | Won 5 |
| » Starters: Jim Perry vs Gaylord Perry | Third | 4½ out |
| » Major-league debuts: Alan Ashby (Indians) |
| Wednesday, July 4 |
| » Lost to Indians (28-52), 5-2 | Tiger Stadium (21-17) | 41-39 | |
| » Starters: Milt Wilcox vs Mike Strahler | Fourth | 4 out |
| Thursday, July 5 |
| » Defeated Indians (28-53), 7-5 | Tiger Stadium (22-17) | 42-39 | |
| » Starters: Brent Strom vs Mickey Lolich | Third | 3 out |
| Friday, July 6 |
| » Lost to Royals (46-40), 12-1 | Royals Stadium (1-3) | 42-40 | |
| » Starters: Joe Coleman vs Steve Busby | Fourth | 4 out |
| Saturday, July 7 |
| » Lost to Royals (47-40), 5-2 | Royals Stadium (1-4) | 42-41 | Lost 2 |
| » Starters: Jim Perry vs Ken Wright | Fourth | 3½ out |
| Sunday, July 8 |
| » Defeated Royals (47-41), 3-0 | Royals Stadium (2-4) | 43-41 | |
| » Starters: Mike Strahler vs Dick Drago | Fourth | 3½ out |
| Monday, July 9 |
| » Lost to Rangers (30-53), 9-7 | Tiger Stadium (22-18) | 43-42 | |
| » Starters: Steve Dunning vs Mickey Lolich | Fourth | 3½ out |
| Tuesday, July 10 |
| » Defeated Rangers (30-54), 5-4 | Tiger Stadium (23-18) | 44-42 | |
| » Starters: Sonny Siebert vs Joe Coleman | Fourth | 2½ out |
| Wednesday, July 11 |
| » Defeated Rangers (30-55), 14-2 | Tiger Stadium (24-18) | 45-42 | Won 2 |
| » Starters: Lloyd Allen vs Jim Perry | Fourth | 2½ out |
| Thursday, July 12 |
| » Defeated Angels (45-41), 7-6 | Tiger Stadium (25-18) | 46-42 | Won 3 |
| » Starters: Bill Singer vs Mickey Lolich | Fourth | 2½ out |
| Friday, July 13 |
| » Defeated Angels (45-42), 8-2 | Tiger Stadium (26-18) | 47-42 | Won 4 |
| » Starters: Clyde Wright vs Mike Strahler | Fourth | 2½ out |
| Saturday, July 14 |
| » Defeated Angels (45-43), 2-1 | Tiger Stadium (27-18) | 48-42 | Won 5 |
| » Starters: Rudy May vs Joe Coleman | Fourth | 1½ out |
| Sunday, July 15 |
| » Lost to Angels (46-43), 6-0 | Tiger Stadium (27-19) | 48-43 | |
| » Starters: Nolan Ryan vs Jim Perry | Fourth | 2½ out |
| Monday, July 16 |
| » Lost to Royals (51-45), 10-2 | Tiger Stadium (27-20) | 48-44 | Lost 2 |
| » Starters: Dick Drago vs Mike Strahler | Fourth | 3 out |
| Tuesday, July 17 |
| » Lost to Royals (52-45), 4-3 | Tiger Stadium (27-21) | 48-45 | Lost 3 |
| » Starters: Al Fitzmorris vs Mickey Lolich | Fourth | 4½ out |
| Wednesday, July 18 |
| » Defeated Royals (52-46), 14-4 | Tiger Stadium (28-21) | 49-45 | |
| » Starters: Steve Busby vs Joe Coleman | Fourth | 3½ out |
| Friday, July 20 |
| » Lost to Rangers (32-61), 8-6 | Arlington Stadium (1-3) | 49-46 | |
| » Starters: Jim Perry vs Jim Merritt | Fourth | 5 out |
| Saturday, July 21 |
| » Lost to Rangers (33-61), 4-3 | Arlington Stadium (1-4) | 49-47 | Lost 2 |
| » Starters: Mickey Lolich vs David Clyde | Fourth | 5½ out |
| Sunday, July 22 |
| » Lost to Rangers (34-61), 4-3 | Arlington Stadium (1-5) | 49-48 | Lost 3 |
| » Starters: Joe Coleman vs Jim Bibby | Fourth | 6 out |
| Thursday, July 26 |
| » Defeated Red Sox (52-45), 6-5 | Tiger Stadium (29-21) | 50-48 | |
| » Starters: Luis Tiant vs Mickey Lolich | Fourth | 6 out |
| Friday, July 27 |
| » Defeated Red Sox (52-46), 4-2 | Tiger Stadium (30-21) | 51-48 | Won 2 |
| » Starters: Bill Lee vs Jim Perry | Fourth | 6 out |
| Saturday, July 28 |
| » Defeated Orioles (54-43), 3-2 | Memorial Stadium (2-2) | 52-48 | Won 3 |
| » Starters: Joe Coleman vs Mike Cuellar | Fourth | 5 out |
| Sunday, July 29 |
| » Defeated Orioles (54-44), 8-3 | Memorial Stadium (3-2) | 53-48 | Won 4 |
| » Starters: Mike Strahler vs Don Hood | Third | 3½ out |
| Monday, July 30 |
| » Defeated Orioles (54-45), 4-3 | Memorial Stadium (4-2) | 54-48 | Won 5 |
| » Starters: Mickey Lolich vs Jesse Jefferson | Third | 2½ out |
| Tuesday, July 31 |
| » Defeated Brewers (50-52), 6-5 | County Stadium (3-1) | 55-48 | Won 6 |
| » Starters: Jim Perry vs Jim Colborn | Third | 2 out |
| » Defeated Brewers (50-53), 9-4 | County Stadium (4-1) | 56-48 | Won 7 |
| » Starters: Woodie Fryman vs Jim Slaton | Third | 2 out |
| Wednesday, August 1 |
| » Defeated Brewers (50-54), 2-1 | County Stadium (5-1) | 57-48 | Won 8 |
| » Starters: Joe Coleman vs Skip Lockwood | Third | 2 out |
| Thursday, August 2 |
| » Lost to Brewers (51-54), 6-3 | County Stadium (5-2) | 57-49 | |
| » Starters: Mike Strahler vs Jerry Bell | Third | 2 out |
| Friday, August 3 |
| » Defeated Yankees (60-51), 7-2 | Tiger Stadium (31-21) | 58-49 | |
| » Starters: Sam McDowell vs Mickey Lolich | Second | 1½ out |
| Saturday, August 4 |
| » Lost to Yankees (61-51), 3-2 | Tiger Stadium (31-22) | 58-50 | |
| » Starters: Fritz Peterson vs Woodie Fryman | Third | 1½ out |
| Sunday, August 5 |
| » Defeated Yankees (61-52), 8-6 | Tiger Stadium (32-22) | 59-50 | |
| » Starters: Pat Dobson vs Joe Coleman | Second | 1½ out |
| » Major-league debuts: Tom Buskey (Yankees) |
| Monday, August 6 |
| » Defeated Yankees (61-53), 5-4 | Tiger Stadium (33-22) | 60-50 | Won 2 |
| » Starters: Mel Stottlemyre vs Mike Strahler | First | -- |
| Tuesday, August 7 |
| » Lost to Athletics (64-48), 8-4 | Tiger Stadium (33-23) | 60-51 | |
| » Starters: Vida Blue vs Mickey Lolich | First | -- |
| » Defeated Athletics (64-49), 2-0 | Tiger Stadium (34-23) | 61-51 | |
| » Starters: Paul Lindblad vs Jim Perry | First | -- |
| Former Tiger Wilbur Cooper dies in Encino, CA at the age of 82. |
| Wednesday, August 8 |
| » Defeated Athletics (64-50), 3-2 | Tiger Stadium (35-23) | 62-51 | Won 2 |
| » Starters: Ken Holtzman vs Woodie Fryman | First | -- |
| Thursday, August 9 |
| » Lost to White Sox (57-58), 5-4 | Tiger Stadium (35-24) | 62-52 | |
| » Starters: Terry Forster vs Joe Coleman | Second | 1½ out |
| Friday, August 10 |
| » Defeated White Sox (57-59), 7-3 | Tiger Stadium (36-24) | 63-52 | |
| » Starters: Steve Stone vs Mike Strahler | First | -- |
| Saturday, August 11 |
| » Defeated White Sox (57-60), 4-2 | Tiger Stadium (37-24) | 64-52 | Won 2 |
| » Starters: Wilbur Wood vs Mickey Lolich | First | -- |
| Sunday, August 12 |
| » Defeated White Sox (57-61), 6-2 | Tiger Stadium (38-24) | 65-52 | Won 3 |
| » Starters: Stan Bahnsen vs Jim Perry | First | -- |
| Monday, August 13 |
| » Defeated Twins (56-60), 9-3 | Metropolitan Stadium (3-1) | 66-52 | Won 4 |
| » Starters: Woodie Fryman vs Bert Blyleven | First | -- |
| Tuesday, August 14 |
| » Lost to Twins (57-60), 12-1 | Metropolitan Stadium (3-2) | 66-53 | |
| » Starters: Joe Coleman vs Dave Goltz | First | -- |
| » Major-league debuts: Tom Veryzer (Tigers) |
| Wednesday, August 15 |
| » Lost to Twins (58-60), 9-7 | Metropolitan Stadium (3-3) | 66-54 | Lost 2 |
| » Starters: Mickey Lolich vs Joe Decker | Second | 1½ out |
| Friday, August 17 |
| » Lost to Angels (55-63), 10-2 | Anaheim Stadium (1-3) | 66-55 | Lost 3 |
| » Starters: Woodie Fryman vs Nolan Ryan | Second | 1½ out |
| Saturday, August 18 |
| » Lost to Angels (56-63), 4-1 | Anaheim Stadium (1-4) | 66-56 | Lost 4 |
| » Starters: Joe Coleman vs Bill Singer | Second | 2½ out |
| Sunday, August 19 |
| » Defeated Angels (56-64), 4-3 | Anaheim Stadium (2-4) | 67-56 | |
| » Starters: Mickey Lolich vs Clyde Wright | Second | 2½ out |
| Monday, August 20 |
| » Lost to Athletics (73-51), 7-2 | Oakland-Alameda County Stadium (1-3) | 67-57 | |
| » Starters: Jim Perry vs Vida Blue | Second | 3½ out |
| Tuesday, August 21 |
| » Defeated Athletics (73-52), 6-4 | Oakland-Alameda County Stadium (2-3) | 68-57 | |
| » Starters: Woodie Fryman vs Ken Holtzman | Second | 3½ out |
| Wednesday, August 22 |
| » Lost to Athletics (74-52), 7-3 | Oakland-Alameda County Stadium (2-4) | 68-58 | |
| » Starters: Joe Coleman vs Blue Moon Odom | Third | 4½ out |
| Former Tiger George Cutshaw dies in San Diego, CA at the age of 87. |
| Thursday, August 23 |
| Former Tiger Gene Ford dies in Dunedin, FL at the age of 93. |
| Friday, August 24 |
| » Defeated White Sox (59-68), 6-5 | Comiskey Park I (2-1) | 69-58 | |
| » Starters: Mickey Lolich vs Wilbur Wood | Third | 4½ out |
| Saturday, August 25 |
| » Defeated White Sox (59-69), 4-2 | Comiskey Park I (3-1) | 70-58 | Won 2 |
| » Starters: Jim Perry vs Stan Bahnsen | Third | 4½ out |
| Sunday, August 26 |
| » Lost to White Sox (60-69), 4-1 | Comiskey Park I (3-2) | 70-59 | |
| » Starters: Joe Coleman vs Jim Kaat | Third | 6 out |
| » Lost to White Sox (61-69), 3-1 | Comiskey Park I (3-3) | 70-60 | Lost 2 |
| » Starters: Woodie Fryman vs Terry Forster | Third | 6 out |
| Monday, August 27 |
| » Lost to Twins (61-68), 5-3 | Tiger Stadium (38-25) | 70-61 | Lost 3 |
| » Starters: Danny Fife vs Mike Strahler | Third | 7 out |
| Tuesday, August 28 |
| » Lost to Twins (62-68), 5-0 | Tiger Stadium (38-26) | 70-62 | Lost 4 |
| » Starters: Joe Decker vs Mickey Lolich | Third | 7 out |
| Wednesday, August 29 |
| » Defeated Twins (62-69), 9-5 | Tiger Stadium (39-26) | 71-62 | |
| » Starters: Dave Goltz vs Jim Perry | Third | 7 out |
| Thursday, August 30 |
| » Lost to Indians (56-78), 3-0 | Tiger Stadium (39-27) | 71-63 | |
| » Starters: Gaylord Perry vs Joe Coleman | Third | 7½ out |
| Friday, August 31 |
| » Lost to Indians (57-78), 6-3 | Tiger Stadium (39-28) | 71-64 | Lost 2 |
| » Manager: Joe Schultz |
| » Starters: Mike Kekich vs Mickey Lolich | Third | 7½ out |
| Saturday, September 1 |
| » Lost to Indians (58-78), 5-4 | Tiger Stadium (39-29) | 71-65 | Lost 3 |
| » Starters: Tom Timmermann vs Woodie Fryman | Third | 8½ out |
| Sunday, September 2 |
| » Defeated Indians (58-79), 2-1 | Tiger Stadium (40-29) | 72-65 | |
| » Starters: Dick Tidrow vs Jim Perry | Third | 8½ out |
| Monday, September 3 |
| » Lost to Yankees (70-68), 4-3 | Tiger Stadium (40-30) | 72-66 | |
| » Starters: Doc Medich vs Joe Coleman | Third | 9 out |
| Tuesday, September 4 |
| » Defeated Yankees (70-69), 2-1 | Tiger Stadium (41-30) | 73-66 | |
| » Starters: Mel Stottlemyre vs Mickey Lolich | Third | 8 out |
| » Major-league debuts: Otto Velez (Yankees) |
| Wednesday, September 5 |
| » Defeated Indians (60-81), 7-3 | Cleveland Stadium (5-3) | 74-66 | Won 2 |
| » Starters: Lerrin LaGrow vs Tom Timmermann | Third | 7 out |
| Thursday, September 6 |
| » Lost to Indians (61-81), 10-4 | Cleveland Stadium (5-4) | 74-67 | |
| » Starters: Woodie Fryman vs Dick Tidrow | Third | 7½ out |
| Friday, September 7 |
| » Lost to Red Sox (78-63), 11-3 | Fenway Park (5-2) | 74-68 | Lost 2 |
| » Starters: Jim Perry vs Marty Pattin | Third | 8½ out |
| Future Tiger Jarrod Patterson is born in Montgomery, AL. |
| Saturday, September 8 |
| » Defeated Red Sox (78-64), 6-1 | Fenway Park (6-2) | 75-68 | |
| » Starters: Joe Coleman vs Bill Lee | Third | 8½ out |
| Sunday, September 9 |
| » Defeated Red Sox (78-65), 5-4 | Fenway Park (7-2) | 76-68 | Won 2 |
| » Starters: Mickey Lolich vs John Curtis | Third | 8 out |
| Monday, September 10 |
| » Lost to Brewers (70-73), 6-5 | County Stadium (5-3) | 76-69 | |
| » Starters: Lerrin LaGrow vs Jim Colborn | Third | 8 out |
| Former Tiger Roy Johnson dies in Tacoma, WA at the age of 71. |
| Tuesday, September 11 |
| » Defeated Brewers (70-74), 4-2 | County Stadium (6-3) | 77-69 | |
| » Starters: Woodie Fryman vs Jim Slaton | Third | 8 out |
| Former Tiger Del Baker dies in San Antonio, TX at the age of 82. |
| Wednesday, September 12 |
| Former Tiger Bernie Boland dies in Detroit, MI at the age of 82. |
| Friday, September 14 |
| » Defeated Brewers (70-78), 2-1 | Tiger Stadium (42-30) | 78-69 | Won 2 |
| » Starters: Jim Colborn vs Mickey Lolich | Third | 9 out |
| Saturday, September 15 |
| » Defeated Brewers (70-79), 4-3 | Tiger Stadium (43-30) | 79-69 | Won 3 |
| » Starters: Jim Slaton vs Joe Coleman | Third | 8 out |
| Sunday, September 16 |
| » Lost to Brewers (71-79), 5-3 | Tiger Stadium (43-31) | 79-70 | |
| » Starters: Eduardo Rodriguez vs Woodie Fryman | Third | 8½ out |
| Tuesday, September 18 |
| » Lost to Orioles (89-61), 6-2 | Tiger Stadium (43-32) | 79-71 | Lost 2 |
| » Starters: Jesse Jefferson vs Mickey Lolich | Third | 10 out |
| Wednesday, September 19 |
| » Defeated Orioles (89-62), 10-1 | Tiger Stadium (44-32) | 80-71 | |
| » Starters: Dave McNally vs Joe Coleman | Third | 9 out |
| Thursday, September 20 |
| » Lost to Orioles (90-62), 9-0 | Tiger Stadium (44-33) | 80-72 | |
| » Starters: Jim Palmer vs Woodie Fryman | Third | 10 out |
| » Major-league debuts: Gary Ignasiak (Tigers) |
| Friday, September 21 |
| » Defeated Red Sox (83-70), 5-1 | Tiger Stadium (45-33) | 81-72 | |
| » Starters: Roger Moret vs Jim Perry | Third | 10 out |
| Saturday, September 22 |
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