| Monday, January 15 |
| Future Giant Wayne Gomes is born in Hampton, VA. |
| Sunday, January 28 |
| Future Giant Jacob Cruz is born in Oxnard, CA. |
| Thursday, February 8 |
| Former Giant Roy Spencer dies in Port Charlotte, FL at the age of 73. |
| Sunday, February 18 |
| Future Giant Shawn Estes is born in San Bernardino, CA. |
| Monday, March 5 |
| Future Giant Felipe Crespo is born in Rio Piedras, P.R. |
| Monday, March 12 |
| Former Giant Frankie Frisch dies in Wilmington, DE at the age of 75. |
| Thursday, April 5 |
| » Defeated Reds (0-1), 4-1 | Riverfront Stadium (1-0) | 1-0 | |
| » Starters: Juan Marichal vs Don Gullett | First | -- |
| » Major-league debuts: Gene Locklear (Reds) |
| Former Giant Tex Jeanes dies in Longview, TX at the age of 73. |
| Saturday, April 7 |
| » Defeated Reds (0-2), 7-5 | Riverfront Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Jim Willoughby vs Jack Billingham | First | -- |
| Sunday, April 8 |
| » Lost to Reds (1-2), 3-1 | Riverfront Stadium (2-1) | 2-1 | |
| » Starters: Tom Bradley vs Ross Grimsley | First | -- |
| Monday, April 9 |
| » Defeated Padres (2-2), 2-1 | Candlestick Park (1-0) | 3-1 | |
| » Starters: Mike Caldwell vs Ron Bryant | First | -- |
| » Major-league debuts: Rich Troedson (Padres) |
| Tuesday, April 10 |
| » Defeated Padres (2-3), 11-2 | Candlestick Park (2-0) | 4-1 | Won 2 |
| » Starters: Mike Corkins vs Juan Marichal | First | -- |
| Wednesday, April 11 |
| » Defeated Astros (4-2), 5-4 | Candlestick Park (3-0) | 5-1 | Won 3 |
| » Starters: Tom Griffin vs Jim Willoughby | First | -- |
| Thursday, April 12 |
| » Defeated Astros (4-3), 9-3 | Candlestick Park (4-0) | 6-1 | Won 4 |
| » Starters: Ken Forsch vs Tom Bradley | First | -- |
| Friday, April 13 |
| » Defeated Reds (4-3), 5-4 | Candlestick Park (5-0) | 7-1 | Won 5 |
| » Starters: Ross Grimsley vs Ron Bryant | First | -- |
| » Major-league debuts: Mike Sadek (Giants) |
| Saturday, April 14 |
| » Lost to Reds (5-3), 3-0 | Candlestick Park (5-1) | 7-2 | |
| » Starters: Roger Nelson vs Jim Barr | First | -- |
| Sunday, April 15 |
| » Lost to Reds (6-3), 11-0 | Candlestick Park (5-2) | 7-3 | Lost 2 |
| » Starters: Don Gullett vs Juan Marichal | Second | ½ out |
| » Lost to Reds (7-3), 7-3 | Candlestick Park (5-3) | 7-4 | Lost 3 |
| » Starters: Jim McGlothlin vs Jim Willoughby | Second | ½ out |
| » Major-league debuts: Mike Phillips (Giants) |
| Tuesday, April 17 |
| » Defeated Braves (3-7), 15-2 | Candlestick Park (6-3) | 8-4 | |
| » Starters: Pat Dobson vs Tom Bradley | Second | ½ out |
| » Defeated Braves (3-8), 2-0 | Candlestick Park (7-3) | 9-4 | Won 2 |
| » Starters: Ron Reed vs Ron Bryant | Second | ½ out |
| Former Giant Vic Aldridge dies in Terre Haute, IN at the age of 80. |
| Wednesday, April 18 |
| » Defeated Braves (3-9), 4-3 | Candlestick Park (8-3) | 10-4 | Won 3 |
| » Starters: Carl Morton vs Sam McDowell | First | -- |
| Thursday, April 19 |
| » Defeated Dodgers (6-8), 8-6 | Dodger Stadium (1-0) | 11-4 | Won 4 |
| » Starters: Jim Willoughby vs Claude Osteen | First | -- |
| Friday, April 20 |
| » Defeated Dodgers (6-9), 7-3 | Dodger Stadium (2-0) | 12-4 | Won 5 |
| » Starters: Juan Marichal vs Al Downing | First | -- |
| Saturday, April 21 |
| » Lost to Dodgers (7-9), 1-0 | Dodger Stadium (2-1) | 12-5 | |
| » Starters: Ron Bryant vs Don Sutton | First | -- |
| Sunday, April 22 |
| » Defeated Dodgers (7-10), 4-2 | Dodger Stadium (3-1) | 13-5 | |
| » Starters: Jim Barr vs Andy Messersmith | First | -- |
| Tuesday, April 24 |
| » Defeated Cubs (9-6), 4-2 | Wrigley Field (1-0) | 14-5 | Won 2 |
| » Starters: Jim Willoughby vs Rick Reuschel | First | -- |
| Wednesday, April 25 |
| » Defeated Cubs (9-7), 5-0 | Wrigley Field (2-0) | 15-5 | Won 3 |
| » Starters: Juan Marichal vs Fergie Jenkins | First | -- |
| Thursday, April 26 |
| » Defeated Cubs (9-8), 7-3 | Wrigley Field (3-0) | 16-5 | Won 4 |
| » Starters: Ron Bryant vs Burt Hooton | First | -- |
| Friday, April 27 |
| » Defeated Cardinals (2-14), 5-0 | Busch Stadium II (1-0) | 17-5 | Won 5 |
| » Starters: Jim Barr vs Bob Gibson | First | -- |
| Saturday, April 28 |
| » Defeated Cardinals (2-15), 1-0 | Busch Stadium II (2-0) | 18-5 | Won 6 |
| » Starters: Jim Willoughby vs Reggie Cleveland | First | -- |
| Sunday, April 29 |
| » Lost to Cardinals (3-15), 8-3 | Busch Stadium II (2-1) | 18-6 | |
| » Starters: Juan Marichal vs Rick Wise | First | -- |
| Tuesday, May 1 |
| » Defeated Pirates (8-8), 8-7 | Candlestick Park (9-3) | 19-6 | |
| » Starters: Bob Moose vs Ron Bryant | First | -- |
| Wednesday, May 2 |
| » Lost to Pirates (9-8), 2-1 | Candlestick Park (9-4) | 19-7 | |
| » Starters: Luke Walker vs Jim Barr | First | -- |
| Thursday, May 3 |
| » Lost to Pirates (10-8), 14-5 | Candlestick Park (9-5) | 19-8 | Lost 2 |
| » Starters: Nelson Briles vs Jim Willoughby | First | -- |
| Friday, May 4 |
| » Defeated Cubs (14-10), 5-4 | Candlestick Park (10-5) | 20-8 | |
| » Starters: Fergie Jenkins vs Juan Marichal | First | -- |
| Saturday, May 5 |
| » Lost to Cubs (15-10), 7-4 | Candlestick Park (10-6) | 20-9 | |
| » Starters: Burt Hooton vs Ron Bryant | First | -- |
| Sunday, May 6 |
| » Defeated Cubs (15-11), 11-9 | Candlestick Park (11-6) | 21-9 | |
| » Starters: Milt Pappas vs Jim Barr | First | -- |
| » Defeated Cubs (15-12), 4-3 | Candlestick Park (12-6) | 22-9 | Won 2 |
| » Starters: Larry Gura vs Jim Willoughby | First | -- |
| Tuesday, May 8 |
| » Defeated Cardinals (5-20), 9-7 | Candlestick Park (13-6) | 23-9 | Won 3 |
| » Starters: Bob Gibson vs Jim Barr | First | -- |
| Wednesday, May 9 |
| » Lost to Cardinals (6-20), 3-1 | Candlestick Park (13-7) | 23-10 | |
| » Starters: Reggie Cleveland vs Ron Bryant | First | -- |
| Thursday, May 10 |
| » Defeated Cardinals (6-21), 6-3 | Candlestick Park (14-7) | 24-10 | |
| » Starters: Rick Wise vs Sam McDowell | First | -- |
| Friday, May 11 |
| » Lost to Dodgers (18-14), 3-2 | Candlestick Park (14-8) | 24-11 | |
| » Starters: Al Downing vs Juan Marichal | First | -- |
| Saturday, May 12 |
| » Defeated Dodgers (18-15), 5-4 | Candlestick Park (15-8) | 25-11 | |
| » Starters: Don Sutton vs Jim Willoughby | First | -- |
| Sunday, May 13 |
| » Lost to Dodgers (19-15), 15-3 | Candlestick Park (15-9) | 25-12 | |
| » Starters: Andy Messersmith vs Jim Barr | First | -- |
| Monday, May 14 |
| » Lost to Padres (13-22), 7-1 | San Diego/Jack Murphy Stadium (0-1) | 25-13 | Lost 2 |
| » Starters: Tom Bradley vs Mike Corkins | First | -- |
| Tuesday, May 15 |
| » Defeated Padres (13-23), 4-2 | San Diego/Jack Murphy Stadium (1-1) | 26-13 | |
| » Starters: Ron Bryant vs Vicente Romo | First | -- |
| Wednesday, May 16 |
| » Lost to Padres (14-23), 4-1 | San Diego/Jack Murphy Stadium (1-2) | 26-14 | |
| » Starters: Juan Marichal vs Mike Caldwell | First | -- |
| Friday, May 18 |
| » Lost to Astros (24-15), 3-1 | Astrodome (0-1) | 26-15 | Lost 2 |
| » Starters: Jim Willoughby vs Dave Roberts | First | -- |
| Saturday, May 19 |
| » Lost to Astros (25-15), 2-1 | Astrodome (0-2) | 26-16 | Lost 3 |
| » Starters: Jim Barr vs Don Wilson | Second | 1 out |
| Sunday, May 20 |
| » Lost to Astros (26-15), 8-7 | Astrodome (0-3) | 26-17 | Lost 4 |
| » Starters: Tom Bradley vs Jerry Reuss | Second | 1 out |
| Monday, May 21 |
| » Defeated Astros (26-16), 9-4 | Astrodome (1-3) | 27-17 | |
| » Starters: Ron Bryant vs Ken Forsch | Second | 1 out |
| Tuesday, May 22 |
| » Defeated Braves (16-23), 7-3 | Atlanta-Fulton County Stadium (1-0) | 28-17 | Won 2 |
| » Starters: Juan Marichal vs Pat Dobson | First | -- |
| Future Giant Julian Tavarez is born in Santiago, D.R. |
| Thursday, May 24 |
| » Lost to Braves (17-23), 2-1 | Atlanta-Fulton County Stadium (1-1) | 28-18 | |
| » Starters: Sam McDowell vs Carl Morton | Second | 2½ out |
| Friday, May 25 |
| » Lost to Expos (17-19), 5-2 | Candlestick Park (15-10) | 28-19 | Lost 2 |
| » Starters: Mike Torrez vs Jim Barr | Second | 1 out |
| Saturday, May 26 |
| » Defeated Expos (17-20), 10-3 | Candlestick Park (16-10) | 29-19 | |
| » Starters: Balor Moore vs Tom Bradley | First | -- |
| Sunday, May 27 |
| » Defeated Expos (17-21), 6-3 | Candlestick Park (17-10) | 30-19 | Won 2 |
| » Starters: Steve Renko vs Ron Bryant | First | -- |
| Monday, May 28 |
| » Defeated Mets (20-21), 6-5 | Candlestick Park (18-10) | 31-19 | Won 3 |
| » Starters: Tommy Moore vs Juan Marichal | First | -- |
| Tuesday, May 29 |
| » Lost to Mets (21-21), 5-2 | Candlestick Park (18-11) | 31-20 | |
| » Starters: Tom Seaver vs Jim Barr | First | -- |
| Wednesday, May 30 |
| » Defeated Mets (21-22), 3-2 | Candlestick Park (19-11) | 32-20 | |
| » Starters: Jon Matlack vs Tom Bradley | First | -- |
| Friday, June 1 |
| » Defeated Phillies (19-28), 2-1 | Candlestick Park (20-11) | 33-20 | Won 2 |
| » Starters: Wayne Twitchell vs Ron Bryant | First | -- |
| Saturday, June 2 |
| » Defeated Phillies (19-29), 11-7 | Candlestick Park (21-11) | 34-20 | Won 3 |
| » Starters: Dick Ruthven vs Juan Marichal | First | -- |
| Former Giant Lore Bader dies in LeRoy, KS at the age of 86. |
| Sunday, June 3 |
| » Defeated Phillies (19-30), 5-4 | Candlestick Park (22-11) | 35-20 | Won 4 |
| » Starters: Ken Brett vs Jim Barr | First | -- |
| Monday, June 4 |
| » Defeated Pirates (23-23), 7-2 | Three Rivers Stadium (1-0) | 36-20 | Won 5 |
| » Starters: Tom Bradley vs Bob Moose | First | -- |
| Tuesday, June 5 |
| » Defeated Pirates (23-24), 3-2 | Three Rivers Stadium (2-0) | 37-20 | Won 6 |
| » Starters: Ron Bryant vs Nelson Briles | First | -- |
| Wednesday, June 6 |
| » Defeated Pirates (23-25), 9-7 | Three Rivers Stadium (3-0) | 38-20 | Won 7 |
| » Starters: Juan Marichal vs Steve Blass | First | -- |
| Friday, June 8 |
| » Lost to Expos (23-25), 17-3 | Parc Jarry (0-1) | 38-21 | |
| » Starters: Jim Barr vs Steve Renko | First | -- |
| Saturday, June 9 |
| » Lost to Expos (24-25), 9-6 | Parc Jarry (0-2) | 38-22 | Lost 2 |
| » Starters: Tom Bradley vs Ernie McAnally | First | -- |
| Sunday, June 10 |
| » Lost to Expos (25-25), 7-6 | Parc Jarry (0-3) | 38-23 | Lost 3 |
| » Starters: Jim Willoughby vs Bill Stoneman | First | -- |
| Monday, June 11 |
| » Defeated Mets (23-29), 2-1 | Shea Stadium (1-0) | 39-23 | |
| » Starters: Ron Bryant vs George Stone | First | -- |
| Tuesday, June 12 |
| » Lost to Mets (24-29), 5-4 | Shea Stadium (1-1) | 39-24 | |
| » Starters: Juan Marichal vs Jim McAndrew | First | -- |
| Wednesday, June 13 |
| » Lost to Mets (25-29), 3-1 | Shea Stadium (1-2) | 39-25 | Lost 2 |
| » Starters: Tom Bradley vs Tom Seaver | First | -- |
| » Major-league debuts: Ron Hodges (Mets) |
| Thursday, June 14 |
| Former Giant Fred Johnson dies in Kerrville, TX at the age of 80. |
| Friday, June 15 |
| » Defeated Phillies (24-35), 4-3 | Veteran's Stadium (1-0) | 40-25 | |
| » Starters: Ron Bryant vs Wayne Twitchell | First | -- |
| Saturday, June 16 |
| » Lost to Phillies (25-35), 5-4 | Veteran's Stadium (1-1) | 40-26 | |
| » Starters: Juan Marichal vs Dick Ruthven | First | -- |
| Sunday, June 17 |
| » Lost to Phillies (26-35), 11-7 | Veteran's Stadium (1-2) | 40-27 | Lost 2 |
| » Starters: Tom Bradley vs Steve Carlton | Second | 1½ out |
| Tuesday, June 19 |
| » Lost to Reds (35-29), 4-0 | Candlestick Park (22-12) | 40-28 | Lost 3 |
| » Starters: Fred Norman vs Ron Bryant | Second | 2 out |
| Wednesday, June 20 |
| » Lost to Reds (36-29), 7-5 | Candlestick Park (22-13) | 40-29 | Lost 4 |
| » Starters: Don Gullett vs Elias Sosa | Second | 3 out |
| Thursday, June 21 |
| » Defeated Reds (36-30), 7-1 | Candlestick Park (23-13) | 41-29 | |
| » Starters: Jack Billingham vs Tom Bradley | Second | 3 out |
| Friday, June 22 |
| » Defeated Astros (38-32), 5-1 | Candlestick Park (24-13) | 42-29 | Won 2 |
| » Starters: Don Wilson vs Jim Barr | Second | 3 out |
| Saturday, June 23 |
| » Lost to Astros (39-32), 6-3 | Candlestick Park (24-14) | 42-30 | |
| » Starters: Jerry Reuss vs Ron Bryant | Second | 3½ out |
| Sunday, June 24 |
| » Lost to Astros (40-32), 7-6 | Candlestick Park (24-15) | 42-31 | Lost 2 |
| » Starters: Dave Roberts vs Charlie Williams | Second | 5 out |
| » Lost to Astros (41-32), 8-3 | Candlestick Park (24-16) | 42-32 | Lost 3 |
| » Starters: J.R. Richard vs Don Carrithers | Second | 5 out |
| Tuesday, June 26 |
| » Lost to Braves (31-42), 9-2 | Candlestick Park (24-17) | 42-33 | Lost 4 |
| » Starters: Ron Schueler vs Tom Bradley | Second | 6½ out |
| Wednesday, June 27 |
| » Defeated Braves (31-43), 6-5 | Candlestick Park (25-17) | 43-33 | |
| » Starters: Adrian Devine vs Ron Bryant | Second | 6 out |
| » Major-league debuts: Adrian Devine (Braves) |
| Thursday, June 28 |
| » Defeated Astros (43-34), 2-1 | Astrodome (2-3) | 44-33 | Won 2 |
| » Starters: Jim Barr vs Dave Roberts | Second | 5½ out |
| Friday, June 29 |
| » Defeated Astros (43-35), 14-3 | Astrodome (3-3) | 45-33 | Won 3 |
| » Starters: Charlie Williams vs J.R. Richard | Second | 5½ out |
| Saturday, June 30 |
| » Lost to Braves (33-45), 5-2 | Atlanta-Fulton County Stadium (1-2) | 45-34 | |
| » Starters: Tom Bradley vs Roric Harrison | Second | 6½ out |
| Sunday, July 1 |
| » Defeated Braves (33-46), 14-6 | Atlanta-Fulton County Stadium (2-2) | 46-34 | |
| » Starters: Ron Bryant vs Ron Schueler | Second | 5½ out |
| » Lost to Braves (34-46), 8-7 | Atlanta-Fulton County Stadium (2-3) | 46-35 | |
| » Starters: Don Carrithers vs Phil Niekro | Second | 5½ out |
| Monday, July 2 |
| » Defeated Braves (34-47), 9-5 | Atlanta-Fulton County Stadium (3-3) | 47-35 | |
| » Starters: Jim Barr vs Jimmy Freeman | Second | 4½ out |
| Tuesday, July 3 |
| » Lost to Reds (43-37), 6-3 | Riverfront Stadium (2-2) | 47-36 | |
| » Starters: Juan Marichal vs Jack Billingham | Second | 4½ out |
| Wednesday, July 4 |
| » Defeated Reds (43-38), 6-2 | Riverfront Stadium (3-2) | 48-36 | |
| » Starters: Tom Bradley vs Tom Hall | Second | 3½ out |
| Future Giant Jay Canizaro is born in Beaumont, TX. |
| Thursday, July 5 |
| » Lost to Reds (44-38), 4-3 | Riverfront Stadium (3-3) | 48-37 | |
| » Starters: Ron Bryant vs Ross Grimsley | Second | 3½ out |
| Friday, July 6 |
| » Lost to Cardinals (42-39), 3-2 | Candlestick Park (25-18) | 48-38 | Lost 2 |
| » Starters: Bob Gibson vs Jim Barr | Second | 4½ out |
| Saturday, July 7 |
| » Lost to Cardinals (43-39), 6-1 | Candlestick Park (25-19) | 48-39 | Lost 3 |
| » Starters: Reggie Cleveland vs Don Carrithers | Second | 5½ out |
| Sunday, July 8 |
| » Defeated Cardinals (43-40), 5-4 | Candlestick Park (26-19) | 49-39 | |
| » Starters: Rick Wise vs Tom Bradley | Second | 5½ out |
| Tuesday, July 10 |
| » Lost to Cubs (51-37), 4-2 | Candlestick Park (26-20) | 49-40 | |
| » Starters: Rick Reuschel vs Ron Bryant | Third | 5½ out |
| Wednesday, July 11 |
| » Defeated Cubs (51-38), 7-3 | Candlestick Park (27-20) | 50-40 | |
| » Starters: Milt Pappas vs Jim Barr | Third | 5½ out |
| Friday, July 13 |
| » Defeated Pirates (40-46), 5-2 | Candlestick Park (28-20) | 51-40 | Won 2 |
| » Starters: Dock Ellis vs Tom Bradley | Second | 6 out |
| Saturday, July 14 |
| » Lost to Pirates (41-46), 7-2 | Candlestick Park (28-21) | 51-41 | |
| » Starters: Jim Rooker vs Ron Bryant | Second | 7 out |
| Sunday, July 15 |
| » Defeated Pirates (41-47), 12-0 | Candlestick Park (29-21) | 52-41 | |
| » Starters: Bob Moose vs Juan Marichal | Second | 7 out |
| Monday, July 16 |
| » Lost to Cardinals (48-42), 3-2 | Busch Stadium II (2-2) | 52-42 | |
| » Starters: Jim Barr vs Bob Gibson | Third | 8 out |
| Tuesday, July 17 |
| » Lost to Cardinals (49-42), 2-1 | Busch Stadium II (2-3) | 52-43 | Lost 2 |
| » Starters: Tom Bradley vs Rich Folkers | Third | 9 out |
| Wednesday, July 18 |
| » Defeated Cardinals (49-43), 8-3 | Busch Stadium II (3-3) | 53-43 | |
| » Starters: Ron Bryant vs Rick Wise | Third | 8 out |
| Friday, July 20 |
| » Defeated Cubs (52-44), 5-4 | Wrigley Field (4-0) | 54-43 | Won 2 |
| » Starters: Juan Marichal vs Rick Reuschel | Third | 8½ out |
| Saturday, July 21 |
| » Defeated Cubs (52-45), 3-1 | Wrigley Field (5-0) | 55-43 | Won 3 |
| » Starters: Jim Barr vs Larry Gura | Third | 7½ out |
| Sunday, July 22 |
| » Defeated Cubs (52-46), 4-1 | Wrigley Field (6-0) | 56-43 | Won 4 |
| » Starters: Tom Bradley vs Fergie Jenkins | Third | 6½ out |
| Thursday, July 26 |
| » Defeated Padres (33-66), 10-2 | Candlestick Park (30-21) | 57-43 | Won 5 |
| » Starters: Steve Arlin vs Ron Bryant | Second | 6 out |
| » Defeated Padres (33-67), 6-5 | Candlestick Park (31-21) | 58-43 | Won 6 |
| » Starters: Clay Kirby vs Jim Willoughby | Second | 6 out |
| Friday, July 27 |
| » Lost to Padres (34-67), 6-2 | Candlestick Park (31-22) | 58-44 | |
| » Starters: Bill Greif vs Juan Marichal | Third | 6 out |
| Saturday, July 28 |
| » Defeated Dodgers (64-39), 5-0 | Dodger Stadium (4-1) | 59-44 | |
| » Starters: Jim Barr vs Don Sutton | Third | 5 out |
| Sunday, July 29 |
| » Lost to Dodgers (65-39), 6-2 | Dodger Stadium (4-2) | 59-45 | |
| » Starters: Tom Bradley vs Andy Messersmith | Third | 6 out |
| Monday, July 30 |
| » Lost to Dodgers (66-39), 5-2 | Dodger Stadium (4-3) | 59-46 | Lost 2 |
| » Starters: Ron Bryant vs Claude Osteen | Third | 7 out |
| Tuesday, July 31 |
| » Defeated Padres (35-70), 5-1 | San Diego/Jack Murphy Stadium (2-2) | 60-46 | |
| » Starters: Juan Marichal vs Steve Arlin | Third | 6 out |
| Wednesday, August 1 |
| » Lost to Padres (36-70), 6-5 | San Diego/Jack Murphy Stadium (2-3) | 60-47 | |
| » Starters: Jim Barr vs Clay Kirby | Third | 6 out |
| Friday, August 3 |
| » Lost to Dodgers (68-41), 3-0 | Candlestick Park (31-23) | 60-48 | Lost 2 |
| » Starters: Andy Messersmith vs Tom Bradley | Third | 7½ out |
| Saturday, August 4 |
| » Defeated Dodgers (68-42), 3-2 | Candlestick Park (32-23) | 61-48 | |
| » Starters: Claude Osteen vs Ron Bryant | Third | 6½ out |
| » Major-league debuts: Bruce Miller (Giants) |
| Sunday, August 5 |
| » Lost to Dodgers (69-42), 4-3 | Candlestick Park (32-24) | 61-49 | |
| » Starters: Tommy John vs Juan Marichal | Third | 7½ out |
| » Major-league debuts: Steve Ontiveros (Giants) |
| Tuesday, August 7 |
| » Lost to Expos (55-56), 2-1 | Candlestick Park (32-25) | 61-50 | Lost 2 |
| » Starters: Steve Renko vs Tom Bradley | Third | 9 out |
| Wednesday, August 8 |
| » Defeated Expos (55-57), 2-1 | Candlestick Park (33-25) | 62-50 | |
| » Starters: Steve Rogers vs Ron Bryant | Third | 8 out |
| Thursday, August 9 |
| » Lost to Expos (56-57), 5-3 | Candlestick Park (33-26) | 62-51 | |
| » Starters: Mike Torrez vs Jim Barr | Third | 9 out |
| Friday, August 10 |
| » Lost to Mets (52-61), 7-1 | Candlestick Park (33-27) | 62-52 | Lost 2 |
| » Starters: Tom Seaver vs Juan Marichal | Third | 9 out |
| Saturday, August 11 |
| » Defeated Mets (52-62), 8-7 | Candlestick Park (34-27) | 63-52 | |
| » Starters: George Stone vs Tom Bradley | Third | 8 out |
| Sunday, August 12 |
| » Defeated Mets (52-63), 4-1 | Candlestick Park (35-27) | 64-52 | Won 2 |
| » Starters: Ray Sadecki vs Ron Bryant | Third | 8 out |
| Tuesday, August 14 |
| » Lost to Phillies (55-63), 4-3 | Candlestick Park (35-28) | 64-53 | |
| » Starters: Jim Lonborg vs Jim Barr | Third | 9½ out |
| Wednesday, August 15 |
| » Defeated Phillies (55-64), 11-2 | Candlestick Park (36-28) | 65-53 | |
| » Starters: Wayne Twitchell vs Juan Marichal | Third | 9½ out |
| Thursday, August 16 |
| » Defeated Phillies (55-65), 2-1 | Candlestick Park (37-28) | 66-53 | Won 2 |
| » Starters: Ken Brett vs Tom Bradley | Third | 9 out |
| Friday, August 17 |
| » Defeated Pirates (57-61), 5-3 | Three Rivers Stadium (4-0) | 67-53 | Won 3 |
| » Starters: Ron Bryant vs Bob Moose | Third | 8 out |
| Saturday, August 18 |
| » Lost to Pirates (58-61), 6-5 | Three Rivers Stadium (4-1) | 67-54 | |
| » Starters: Jim Barr vs Nelson Briles | Third | 8 out |
| Sunday, August 19 |
| » Lost to Pirates (59-61), 5-0 | Three Rivers Stadium (4-2) | 67-55 | Lost 2 |
| » Starters: Juan Marichal vs Jim Rooker | Third | 9 out |
| Monday, August 20 |
| » Defeated Expos (59-64), 6-4 | Parc Jarry (1-3) | 68-55 | |
| » Starters: Tom Bradley vs Mike Torrez | Third | 8½ out |
| Tuesday, August 21 |
| » Defeated Expos (59-65), 3-1 | Parc Jarry (2-3) | 69-55 | Won 2 |
| » Starters: Ron Bryant vs Steve Renko | Third | 7½ out |
| Wednesday, August 22 |
| » Defeated Expos (59-66), 3-2 | Parc Jarry (3-3) | 70-55 | Won 3 |
| » Starters: Jim Barr vs Steve Rogers | Third | 6½ out |
| Thursday, August 23 |
| » Major-league debuts: Matt Alexander (Cubs) |
| Friday, August 24 |
| » Lost to Mets (58-68), 1-0 | Shea Stadium (1-3) | 70-56 | |
| » Starters: Juan Marichal vs Jerry Koosman | Third | 8 out |
| Saturday, August 25 |
| » Defeated Mets (58-69), 1-0 | Shea Stadium (2-3) | 71-56 | |
| » Starters: Tom Bradley vs Tom Seaver | Third | 8 out |
| Future Giant Dante Powell is born in Long Beach, CA. |
| Sunday, August 26 |
| » Defeated Mets (58-70), 5-4 | Shea Stadium (3-3) | 72-56 | Won 2 |
| » Starters: Ron Bryant vs Ray Sadecki | Third | 8 out |
| Monday, August 27 |
| » Lost to Phillies (60-70), 7-4 | Veteran's Stadium (1-3) | 72-57 | |
| » Starters: Jim Barr vs Jim Lonborg | Third | 8 out |
| Tuesday, August 28 |
| » Lost to Phillies (61-70), 1-0 | Veteran's Stadium (1-4) | 72-58 | Lost 2 |
| » Starters: Juan Marichal vs Wayne Twitchell | Third | 9 out |
| Wednesday, August 29 |
| » Defeated Phillies (61-71), 3-1 | Veteran's Stadium (2-4) | 73-58 | |
| » Starters: Tom Bradley vs Ken Brett | Third | 8 out |
| Friday, August 31 |
| » Lost to Braves (65-70), 10-4 | Candlestick Park (37-29) | 73-59 | |
| » Starters: Roric Harrison vs Ron Bryant | Third | 8½ out |
| Saturday, September 1 |
| » Defeated Braves (65-71), 5-4 | Candlestick Park (38-29) | 74-59 | |
| » Starters: Phil Niekro vs Jim Barr | Third | 7½ out |
| Sunday, September 2 |
| » Defeated Braves (65-72), 5-4 | Candlestick Park (39-29) | 75-59 | Won 2 |
| » Starters: Ron Schueler vs Juan Marichal | Third | 6 out |
| » Defeated Braves (65-73), 11-3 | Candlestick Park (40-29) | 76-59 | Won 3 |
| » Starters: Carl Morton vs John D'Acquisto | Third | 6 out |
| » Major-league debuts: John D'Acquisto (Giants) |
| Monday, September 3 |
| » Defeated Dodgers (83-55), 11-8 | Candlestick Park (41-29) | 77-59 | Won 4 |
| » Starters: Tommy John vs Tom Bradley | Second | 5 out |
| Tuesday, September 4 |
| » Defeated Dodgers (83-56), 3-1 | Candlestick Park (42-29) | 78-59 | Won 5 |
| » Starters: Al Downing vs Ron Bryant | Third | 5 out |
| Future Giant Aaron Fultz is born in Memphis, TN. |
| Wednesday, September 5 |
| » Defeated Dodgers (83-57), 7-0 | Candlestick Park (43-29) | 79-59 | Won 6 |
| » Starters: Doug Rau vs Jim Barr | Third | 5 out |
| Friday, September 7 |
| » Defeated Astros (71-72), 9-6 | Candlestick Park (44-29) | 80-59 | Won 7 |
| » Starters: Dave Roberts vs Tom Bradley | Third | 4 out |
| Saturday, September 8 |
| » Lost to Astros (72-72), 9-7 | Candlestick Park (44-30) | 80-60 | |
| » Starters: J.R. Richard vs Ron Bryant | Third | 4 out |
| Sunday, September 9 |
| » Lost to Astros (73-72), 5-4 | Candlestick Park (44-31) | 80-61 | Lost 2 |
| » Starters: Jerry Reuss vs Jim Barr | Third | 5½ out |
| Monday, September 10 |
| » Lost to Braves (70-76), 10-4 | Atlanta-Fulton County Stadium (3-4) | 80-62 | Lost 3 |
| » Starters: Juan Marichal vs Wenty Ford | Third | 6 out |
| » Major-league debuts: Wenty Ford (Braves) |
| Tuesday, September 11 |
| » Lost to Braves (71-76), 6-5 | Atlanta-Fulton County Stadium (3-5) | 80-63 | Lost 4 |
| » Starters: Tom Bradley vs Ron Schueler | Third | 7 out |
| Wednesday, September 12 |
| » Lost to Braves (72-76), 10-4 | Atlanta-Fulton County Stadium (3-6) | 80-64 | Lost 5 |
| » Starters: Ron Bryant vs Carl Morton | Third | 8 out |
| Thursday, September 13 |
| » Defeated Padres (53-92), 8-6 | San Diego/Jack Murphy Stadium (3-3) | 81-64 | |
| » Starters: Jim Barr vs Steve Arlin | Third | 7½ out |
| Former Giant Johnny McCarthy dies in Mundelein, IL at the age of 64. |
| Friday, September 14 |
| » Lost to Padres (54-92), 4-3 | San Diego/Jack Murphy Stadium (3-4) | 81-65 | |
| » Starters: Juan Marichal vs Clay Kirby | Third | 8½ out |
| Saturday, September 15 |
| » Defeated Padres (54-93), 5-2 | San Diego/Jack Murphy Stadium (4-4) | 82-65 | |
| » Starters: Tom Bradley vs Rich Troedson | Third | 8½ out |
| Sunday, September 16 |
| » Defeated Padres (54-94), 9-4 | San Diego/Jack Murphy Stadium (5-4) | 83-65 | Won 2 |
| » Starters: Ron Bryant vs Bill Greif | Third | 8½ out |
| Monday, September 17 |
| » Lost to Dodgers (87-64), 7-2 | Dodger Stadium (4-4) | 83-66 | |
| » Starters: Jim Barr vs Don Sutton | Third | 8½ out |
| Tuesday, September 18 |
| » Lost to Dodgers (88-64), 3-1 | Dodger Stadium (4-5) | 83-67 | Lost 2 |
| » Starters: Juan Marichal vs Tommy John | Third | 9½ out |
| Wednesday, September 19 |
| » Lost to Reds (94-58), 5-1 | Candlestick Park (44-32) | 83-68 | Lost 3 |
| » Starters: Fred Norman vs Tom Bradley | Third | 10½ out |
| Thursday, September 20 |
| » Defeated Reds (94-59), 7-5 | Candlestick Park (45-32) | 84-68 | |
| » Starters: Ross Grimsley vs Ron Bryant | Third | 9½ out |
| Friday, September 21 |
| » Lost to Padres (57-96), 3-1 | Candlestick Park (45-33) | 84-69 | |
| » Starters: Bill Greif vs Jim Barr | Third | 10 out |
| » Defeated Padres (57-97), 7-2 | Candlestick Park (46-33) | 85-69 | |
| » Starters: Randy Jones vs John D'Acquisto | Third | 10 out |
| Saturday, September 22 |
| » Defeated Padres (57-98), 5-2 | Candlestick Park (47-33) | 86-69 | Won 2 |
| » Starters: Steve Arlin vs Juan Marichal | Third | 10 out |
| Sunday, September 23 |
| » Lost to Padres (58-98), 11-9 | Candlestick Park (47-34) | 86-70 | |
| » Starters: Clay Kirby vs Tom Bradley | Third | 10 out |
| Monday, September 24 |
| » Lost to Astros (79-79), 10-6 | Astrodome (3-4) | 86-71 | Lost 2 |
| » Starters: Ron Bryant vs Jerry Reuss | Third | 11 out |
| Tuesday, September 25 |
| » Lost to Astros (80-79), 5-1 | Astrodome (3-5) | 86-72 | Lost 3 |
| » |
