| Thursday, April 5 |
| » Major-league debuts: Gene Locklear (Reds) |
| Friday, April 6 |
| » Lost to Twins (1-0), 8-3 | Oakland-Alameda County Stadium (0-1) | 0-1 | |
| » Starters: Bert Blyleven vs Catfish Hunter | Third | 1 out |
| Saturday, April 7 |
| » Lost to Twins (2-0), 5-3 | Oakland-Alameda County Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Bill Hands vs Blue Moon Odom | Fifth | 2 out |
| Sunday, April 8 |
| » Lost to Twins (3-0), 4-2 | Oakland-Alameda County Stadium (0-3) | 0-3 | Lost 3 |
| » Starters: Jim Kaat vs Ken Holtzman | Sixth | 3 out |
| Wednesday, April 11 |
| » Defeated White Sox (1-1), 12-2 | Comiskey Park I (1-0) | 1-3 | |
| » Starters: Vida Blue vs Wilbur Wood | Fourth | 2½ out |
| Thursday, April 12 |
| » Lost to White Sox (2-1), 6-3 | Comiskey Park I (1-1) | 1-4 | |
| » Starters: Darold Knowles vs Stan Bahnsen | Fifth | 2½ out |
| Friday, April 13 |
| » Lost to Twins (4-2), 8-4 | Metropolitan Stadium (0-1) | 1-5 | Lost 2 |
| » Starters: Blue Moon Odom vs Jim Kaat | Sixth | 3½ out |
| Saturday, April 14 |
| » Defeated Twins (4-3), 2-1 | Metropolitan Stadium (1-1) | 2-5 | |
| » Starters: Ken Holtzman vs Bert Blyleven | Fifth | 3½ out |
| » Major-league debuts: Jerry Terrell (Twins) |
| Tuesday, April 17 |
| » Lost to Royals (8-2), 5-4 | Royals Stadium (0-1) | 2-6 | |
| » Starters: Vida Blue vs Wayne Simpson | Fifth | 5 out |
| Wednesday, April 18 |
| » Defeated Royals (8-3), 7-6 | Royals Stadium (1-1) | 3-6 | |
| » Starters: Catfish Hunter vs Dick Drago | Fourth | 4 out |
| Thursday, April 19 |
| » Lost to Royals (9-3), 16-8 | Royals Stadium (1-2) | 3-7 | |
| » Starters: Blue Moon Odom vs Paul Splittorff | Fourth | 5 out |
| Friday, April 20 |
| » Defeated Angels (4-5), 4-3 | Oakland-Alameda County Stadium (1-3) | 4-7 | |
| » Starters: Clyde Wright vs Ken Holtzman | Fifth | 4 out |
| Saturday, April 21 |
| » Lost to Angels (5-5), 4-2 | Oakland-Alameda County Stadium (1-4) | 4-8 | |
| » Starters: Bill Singer vs Vida Blue | Fifth | 4½ out |
| Sunday, April 22 |
| » Defeated Angels (5-6), 3-2 | Oakland-Alameda County Stadium (2-4) | 5-8 | |
| » Starters: Nolan Ryan vs Catfish Hunter | Fifth | 4 out |
| Monday, April 23 |
| » Lost to Angels (6-6), 4-0 | Oakland-Alameda County Stadium (2-5) | 5-9 | |
| » Starters: Rudy May vs Blue Moon Odom | Fifth | 4½ out |
| Tuesday, April 24 |
| » Defeated Indians (6-10), 4-0 | Oakland-Alameda County Stadium (3-5) | 6-9 | |
| » Starters: Gaylord Perry vs Ken Holtzman | Fifth | 4 out |
| Wednesday, April 25 |
| » Lost to Indians (7-10), 1-0 | Oakland-Alameda County Stadium (3-6) | 6-10 | |
| » Starters: Dick Tidrow vs Rollie Fingers | Fifth | 4½ out |
| Thursday, April 26 |
| » Defeated Indians (7-11), 3-2 | Oakland-Alameda County Stadium (4-6) | 7-10 | |
| » Starters: Brent Strom vs Catfish Hunter | Fifth | 3½ out |
| Friday, April 27 |
| » Defeated Orioles (9-8), 4-3 | Oakland-Alameda County Stadium (5-6) | 8-10 | Won 2 |
| » Starters: Mike Cuellar vs Blue Moon Odom | Fifth | 3 out |
| Saturday, April 28 |
| » Lost to Orioles (10-8), 2-1 | Oakland-Alameda County Stadium (5-7) | 8-11 | |
| » Starters: Jim Palmer vs Ken Holtzman | Fifth | 4½ out |
| Sunday, April 29 |
| » Defeated Orioles (10-9), 4-3 | Oakland-Alameda County Stadium (6-7) | 9-11 | |
| » Starters: Dave McNally vs Catfish Hunter | Fourth | 3½ out |
| Tuesday, May 1 |
| » Lost to Brewers (10-9), 4-3 | County Stadium (0-1) | 9-12 | |
| » Starters: Blue Moon Odom vs Jim Colborn | Fifth | 4½ out |
| Wednesday, May 2 |
| » Defeated Brewers (10-10), 7-3 | County Stadium (1-1) | 10-12 | |
| » Starters: Ken Holtzman vs Jerry Bell | Fifth | 4½ out |
| Friday, May 4 |
| » Defeated Indians (10-13), 11-4 | Cleveland Stadium (1-0) | 11-12 | Won 2 |
| » Starters: Catfish Hunter vs Gaylord Perry | Fifth | 4½ out |
| Saturday, May 5 |
| » Lost to Indians (11-13), 6-5 | Cleveland Stadium (1-1) | 11-13 | |
| » Starters: Blue Moon Odom vs Milt Wilcox | Fifth | 5½ out |
| Sunday, May 6 |
| » Defeated Indians (11-14), 12-0 | Cleveland Stadium (2-1) | 12-13 | |
| » Starters: Ken Holtzman vs Dick Tidrow | Fifth | 5 out |
| » Defeated Indians (11-15), 7-3 | Cleveland Stadium (3-1) | 13-13 | Won 2 |
| » Starters: Vida Blue vs Brent Strom | Fifth | 5 out |
| Monday, May 7 |
| » Lost to Orioles (12-13), 8-2 | Memorial Stadium (0-1) | 13-14 | |
| » Starters: Rollie Fingers vs Doyle Alexander | Fifth | 5 out |
| Wednesday, May 9 |
| » Defeated Orioles (12-14), 4-3 | Memorial Stadium (1-1) | 14-14 | |
| » Starters: Catfish Hunter vs Dave McNally | Fourth | 5 out |
| Thursday, May 10 |
| » Defeated Rangers (9-15), 17-2 | Arlington Stadium (1-0) | 15-14 | Won 2 |
| » Starters: Ken Holtzman vs Mike Paul | Fourth | 5 out |
| Friday, May 11 |
| » Defeated Rangers (9-16), 4-3 | Arlington Stadium (2-0) | 16-14 | Won 3 |
| » Starters: Vida Blue vs Rich Hand | Third | 5 out |
| Saturday, May 12 |
| » Defeated Rangers (9-17), 4-2 | Arlington Stadium (3-0) | 17-14 | Won 4 |
| » Starters: Blue Moon Odom vs Pete Broberg | Third | 4 out |
| Sunday, May 13 |
| » Lost to Rangers (10-17), 7-2 | Arlington Stadium (3-1) | 17-15 | |
| » Starters: Catfish Hunter vs Sonny Siebert | Fourth | 4 out |
| Monday, May 14 |
| » Defeated White Sox (18-9), 5-1 | Oakland-Alameda County Stadium (7-7) | 18-15 | |
| » Starters: Wilbur Wood vs Ken Holtzman | Fourth | 3 out |
| Future Athletic Brad Rigby is born in Milwaukee, WI. |
| Tuesday, May 15 |
| » Lost to White Sox (19-9), 6-5 | Oakland-Alameda County Stadium (7-8) | 18-16 | |
| » Starters: Stan Bahnsen vs Vida Blue | Fourth | 4 out |
| Wednesday, May 16 |
| » Lost to Angels (18-13), 7-2 | Anaheim Stadium (0-1) | 18-17 | Lost 2 |
| » Starters: Blue Moon Odom vs Clyde Wright | Fourth | 4 out |
| Thursday, May 17 |
| » Defeated Angels (18-14), 4-0 | Anaheim Stadium (1-1) | 19-17 | |
| » Starters: Catfish Hunter vs Rudy May | Fourth | 4 out |
| Friday, May 18 |
| » Defeated Royals (21-16), 5-4 | Oakland-Alameda County Stadium (8-8) | 20-17 | Won 2 |
| » Starters: Steve Busby vs Ken Holtzman | Fourth | 3 out |
| Saturday, May 19 |
| » Lost to Royals (22-16), 5-2 | Oakland-Alameda County Stadium (8-9) | 20-18 | |
| » Starters: Dick Drago vs Vida Blue | Fourth | 3 out |
| Sunday, May 20 |
| » Lost to Royals (23-16), 8-2 | Oakland-Alameda County Stadium (8-10) | 20-19 | Lost 2 |
| » Starters: Paul Splittorff vs Blue Moon Odom | Fifth | 3½ out |
| Monday, May 21 |
| » Defeated Royals (23-17), 5-0 | Oakland-Alameda County Stadium (9-10) | 21-19 | |
| » Starters: Bruce DalCanton vs Catfish Hunter | Fourth | 3 out |
| Tuesday, May 22 |
| » Defeated Rangers (12-24), 4-1 | Oakland-Alameda County Stadium (10-10) | 22-19 | Won 2 |
| » Starters: Sonny Siebert vs Ken Holtzman | Fourth | 3 out |
| Wednesday, May 23 |
| » Defeated Rangers (12-25), 8-6 | Oakland-Alameda County Stadium (11-10) | 23-19 | Won 3 |
| » Starters: Pete Broberg vs Vida Blue | Third | 3 out |
| Friday, May 25 |
| » Lost to Tigers (22-20), 1-0 | Tiger Stadium (0-1) | 23-20 | |
| » Starters: Catfish Hunter vs Jim Perry | Fifth | 3½ out |
| Saturday, May 26 |
| » Lost to Tigers (23-20), 8-5 | Tiger Stadium (0-2) | 23-21 | Lost 2 |
| » Starters: Ken Holtzman vs Woodie Fryman | Fifth | 4 out |
| Former Athletic Chicken Hawks dies in San Rafael, CA at the age of 78. |
| Monday, May 28 |
| » Lost to Tigers (24-20), 4-3 | Tiger Stadium (0-3) | 23-22 | Lost 3 |
| » Starters: Blue Moon Odom vs Joe Coleman | Fifth | 5½ out |
| Tuesday, May 29 |
| » Lost to Yankees (23-22), 7-1 | Yankee Stadium (0-1) | 23-23 | Lost 4 |
| » Starters: Catfish Hunter vs Fritz Peterson | Fourth | 6 out |
| Wednesday, May 30 |
| » Lost to Yankees (24-22), 4-3 | Yankee Stadium (0-2) | 23-24 | Lost 5 |
| » Starters: Vida Blue vs Doc Medich | Fifth | 6 out |
| Thursday, May 31 |
| » Defeated Yankees (24-23), 6-0 | Yankee Stadium (1-2) | 24-24 | |
| » Starters: Ken Holtzman vs Mel Stottlemyre | Fifth | 6 out |
| Friday, June 1 |
| » Lost to Red Sox (21-23), 6-2 | Fenway Park (0-1) | 24-25 | |
| » Starters: Dave Hamilton vs Marty Pattin | Fourth | 6 out |
| Saturday, June 2 |
| » Defeated Red Sox (21-24), 3-1 | Fenway Park (1-1) | 25-25 | |
| » Starters: Catfish Hunter vs Bill Lee | Fifth | 5 out |
| Sunday, June 3 |
| » Defeated Red Sox (21-25), 12-1 | Fenway Park (2-1) | 26-25 | Won 2 |
| » Starters: Vida Blue vs Luis Tiant | Fifth | 4 out |
| Monday, June 4 |
| » Lost to Brewers (23-26), 2-0 | Oakland-Alameda County Stadium (11-11) | 26-26 | |
| » Starters: Jim Colborn vs Ken Holtzman | Fifth | 4½ out |
| Tuesday, June 5 |
| » Lost to Brewers (24-26), 5-4 | Oakland-Alameda County Stadium (11-12) | 26-27 | Lost 2 |
| » Starters: Chris Short vs Dave Hamilton | Fifth | 4½ out |
| Wednesday, June 6 |
| » Defeated Brewers (24-27), 11-1 | Oakland-Alameda County Stadium (12-12) | 27-27 | |
| » Starters: Jim Slaton vs Catfish Hunter | Fifth | 3½ out |
| Friday, June 8 |
| » Lost to Tigers (29-24), 4-1 | Oakland-Alameda County Stadium (12-13) | 27-28 | |
| » Starters: Mickey Lolich vs Vida Blue | Fifth | 5 out |
| Saturday, June 9 |
| » Defeated Tigers (29-25), 4-0 | Oakland-Alameda County Stadium (13-13) | 28-28 | |
| » Starters: Jim Perry vs Ken Holtzman | Fifth | 5 out |
| Sunday, June 10 |
| » Defeated Tigers (29-26), 5-0 | Oakland-Alameda County Stadium (14-13) | 29-28 | Won 2 |
| » Starters: Joe Coleman vs Catfish Hunter | Fourth | 4½ out |
| Tuesday, June 12 |
| » Defeated Yankees (30-27), 4-2 | Oakland-Alameda County Stadium (15-13) | 30-28 | Won 3 |
| » Starters: Steve Kline vs Vida Blue | Fourth | 3½ out |
| Wednesday, June 13 |
| » Lost to Yankees (31-27), 8-3 | Oakland-Alameda County Stadium (15-14) | 30-29 | |
| » Starters: Fritz Peterson vs Ken Holtzman | Fifth | 4½ out |
| Thursday, June 14 |
| » Defeated Yankees (31-28), 3-0 | Oakland-Alameda County Stadium (16-14) | 31-29 | |
| » Starters: Doc Medich vs Dave Hamilton | Fourth | 4 out |
| Friday, June 15 |
| » Defeated Red Sox (27-29), 8-3 | Oakland-Alameda County Stadium (17-14) | 32-29 | Won 2 |
| » Starters: Marty Pattin vs Catfish Hunter | Third | 3 out |
| Saturday, June 16 |
| » Defeated Red Sox (27-30), 4-3 | Oakland-Alameda County Stadium (18-14) | 33-29 | Won 3 |
| » Starters: Bill Lee vs Vida Blue | Third | 3 out |
| Sunday, June 17 |
| » Lost to Red Sox (28-30), 4-2 | Oakland-Alameda County Stadium (18-15) | 33-30 | |
| » Starters: Luis Tiant vs Ken Holtzman | Fourth | 3 out |
| Monday, June 18 |
| » Defeated Royals (36-31), 9-5 | Royals Stadium (2-2) | 34-30 | |
| » Starters: Dave Hamilton vs Mark Littell | Fourth | 3 out |
| Tuesday, June 19 |
| » Defeated Royals (36-32), 11-6 | Royals Stadium (3-2) | 35-30 | Won 2 |
| » Starters: Catfish Hunter vs Paul Splittorff | Third | 2½ out |
| Wednesday, June 20 |
| » Lost to Royals (37-32), 5-4 | Royals Stadium (3-3) | 35-31 | |
| » Starters: Vida Blue vs Steve Busby | Fourth | 3 out |
| Thursday, June 21 |
| » Lost to White Sox (34-27), 2-0 | Comiskey Park I (1-2) | 35-32 | Lost 2 |
| » Starters: Ken Holtzman vs Stan Bahnsen | Fourth | 3 out |
| Friday, June 22 |
| » Defeated White Sox (34-28), 7-1 | Comiskey Park I (2-2) | 36-32 | |
| » Starters: Dave Hamilton vs Wilbur Wood | Fourth | 3 out |
| Saturday, June 23 |
| » Defeated White Sox (34-29), 14-3 | Comiskey Park I (3-2) | 37-32 | Won 2 |
| » Starters: Catfish Hunter vs Eddie Fisher | Second | 3 out |
| Sunday, June 24 |
| » Defeated White Sox (34-30), 7-0 | Comiskey Park I (4-2) | 38-32 | Won 3 |
| » Starters: Vida Blue vs Steve Stone | Third | 1 out |
| » Lost to White Sox (35-30), 11-1 | Comiskey Park I (4-3) | 38-33 | |
| » Starters: Blue Moon Odom vs Bart Johnson | Third | 1 out |
| Future Athletic Rob Ryan is born in Havre, MT. |
| Monday, June 25 |
| » Lost to Rangers (23-42), 4-2 | Arlington Stadium (3-2) | 38-34 | Lost 2 |
| » Starters: Ken Holtzman vs Sonny Siebert | Fourth | 3 out |
| Tuesday, June 26 |
| » Defeated Rangers (23-43), 6-2 | Arlington Stadium (4-2) | 39-34 | |
| » Starters: Dave Hamilton vs Jim Merritt | Third | 1½ out |
| Wednesday, June 27 |
| » Defeated Royals (40-36), 3-2 | Oakland-Alameda County Stadium (19-15) | 40-34 | Won 2 |
| » Starters: Paul Splittorff vs Catfish Hunter | Second | 1½ out |
| Thursday, June 28 |
| » Defeated Royals (40-37), 3-2 | Oakland-Alameda County Stadium (20-15) | 41-34 | Won 3 |
| » Starters: Steve Busby vs Vida Blue | First | -- |
| Future Athletic Jose Flores is born in New York, NY. |
| Friday, June 29 |
| » Lost to White Sox (38-32), 4-3 | Oakland-Alameda County Stadium (20-16) | 41-35 | |
| » Starters: Stan Bahnsen vs Ken Holtzman | Second | 3 out |
| Saturday, June 30 |
| » Defeated White Sox (38-33), 3-2 | Oakland-Alameda County Stadium (21-16) | 42-35 | |
| » Starters: Wilbur Wood vs Dave Hamilton | First | -- |
| Sunday, July 1 |
| » Defeated White Sox (38-34), 6-4 | Oakland-Alameda County Stadium (22-16) | 43-35 | Won 2 |
| » Starters: Eddie Fisher vs Catfish Hunter | First | -- |
| » Defeated White Sox (38-35), 3-0 | Oakland-Alameda County Stadium (23-16) | 44-35 | Won 3 |
| » Starters: Bart Johnson vs Blue Moon Odom | First | -- |
| Monday, July 2 |
| » Lost to Angels (40-36), 4-2 | Oakland-Alameda County Stadium (23-17) | 44-36 | |
| » Starters: Nolan Ryan vs Vida Blue | Second | 3 out |
| Tuesday, July 3 |
| » Defeated Angels (40-37), 3-0 | Oakland-Alameda County Stadium (24-17) | 45-36 | |
| » Starters: Rudy May vs Ken Holtzman | First | -- |
| Wednesday, July 4 |
| » Lost to Angels (41-37), 3-1 | Oakland-Alameda County Stadium (24-18) | 45-37 | |
| » Starters: Bill Singer vs Dave Hamilton | First | -- |
| Friday, July 6 |
| » Defeated Orioles (40-35), 7-5 | Memorial Stadium (2-1) | 46-37 | |
| » Starters: Catfish Hunter vs Jim Palmer | First | -- |
| » Lost to Orioles (41-35), 5-3 | Memorial Stadium (2-2) | 46-38 | |
| » Starters: Vida Blue vs Dave McNally | First | -- |
| Former Athletic Wickey McAvoy dies in Rochester, NY at the age of 79. |
| Saturday, July 7 |
| » Defeated Orioles (41-36), 5-4 | Memorial Stadium (3-2) | 47-38 | |
| » Starters: Ken Holtzman vs Mike Cuellar | First | -- |
| Sunday, July 8 |
| » Defeated Orioles (41-37), 6-5 | Memorial Stadium (4-2) | 48-38 | Won 2 |
| » Starters: Dave Hamilton vs Jesse Jefferson | First | -- |
| Tuesday, July 10 |
| » Lost to Indians (30-56), 7-5 | Cleveland Stadium (3-2) | 48-39 | |
| » Starters: Blue Moon Odom vs Dick Tidrow | First | -- |
| Wednesday, July 11 |
| » Defeated Indians (30-57), 9-3 | Cleveland Stadium (4-2) | 49-39 | |
| » Starters: Catfish Hunter vs Gaylord Perry | First | -- |
| Thursday, July 12 |
| » Defeated Brewers (43-44), 8-4 | County Stadium (2-1) | 50-39 | Won 2 |
| » Starters: Vida Blue vs Jim Slaton | First | -- |
| Friday, July 13 |
| » Defeated Brewers (43-45), 13-4 | County Stadium (3-1) | 51-39 | Won 3 |
| » Starters: Ken Holtzman vs Skip Lockwood | First | -- |
| Saturday, July 14 |
| » Lost to Brewers (44-45), 5-1 | County Stadium (3-2) | 51-40 | |
| » Starters: Dave Hamilton vs Jim Colborn | First | -- |
| Sunday, July 15 |
| » Defeated Brewers (44-46), 8-5 | County Stadium (4-2) | 52-40 | |
| » Starters: Blue Moon Odom vs Jerry Bell | First | -- |
| Monday, July 16 |
| » Lost to Orioles (47-39), 7-5 | Oakland-Alameda County Stadium (24-19) | 52-41 | |
| » Starters: Jesse Jefferson vs Catfish Hunter | First | -- |
| » Major-league debuts: Don Hood (Orioles) |
| Tuesday, July 17 |
| » Defeated Orioles (47-40), 3-1 | Oakland-Alameda County Stadium (25-19) | 53-41 | |
| » Starters: Dave McNally vs Vida Blue | First | -- |
| Wednesday, July 18 |
| » Lost to Orioles (48-40), 5-2 | Oakland-Alameda County Stadium (25-20) | 53-42 | |
| » Starters: Jim Palmer vs Ken Holtzman | First | -- |
| Friday, July 20 |
| » Defeated Indians (35-61), 6-5 | Oakland-Alameda County Stadium (26-20) | 54-42 | |
| » Starters: Gaylord Perry vs Catfish Hunter | First | -- |
| Saturday, July 21 |
| » Defeated Indians (35-62), 5-2 | Oakland-Alameda County Stadium (27-20) | 55-42 | Won 2 |
| » Starters: Milt Wilcox vs Vida Blue | First | -- |
| Sunday, July 22 |
| » Defeated Indians (35-63), 5-2 | Oakland-Alameda County Stadium (28-20) | 56-42 | Won 3 |
| » Starters: Dick Bosman vs Ken Holtzman | First | -- |
| Thursday, July 26 |
| » Lost to Twins (50-47), 5-1 | Metropolitan Stadium (1-2) | 56-43 | |
| » Starters: Vida Blue vs Dick Woodson | First | -- |
| » Lost to Twins (51-47), 7-5 | Metropolitan Stadium (1-3) | 56-44 | Lost 2 |
| » Starters: Ken Holtzman vs Jim Kaat | First | -- |
| Friday, July 27 |
| » Lost to Twins (52-47), 8-2 | Metropolitan Stadium (1-4) | 56-45 | Lost 3 |
| » Starters: Dave Hamilton vs Bert Blyleven | First | -- |
| Saturday, July 28 |
| » Defeated Rangers (37-62), 6-4 | Oakland-Alameda County Stadium (29-20) | 57-45 | |
| » Starters: Steve Dunning vs Blue Moon Odom | First | -- |
| Sunday, July 29 |
| » Lost to Rangers (38-62), 3-0 | Oakland-Alameda County Stadium (29-21) | 57-46 | |
| » Starters: Jackie Brown vs Paul Lindblad | First | -- |
| » Defeated Rangers (38-63), 7-4 | Oakland-Alameda County Stadium (30-21) | 58-46 | |
| » Starters: Don Durham vs Glenn Abbott | First | -- |
| Monday, July 30 |
| » Lost to Rangers (39-63), 6-0 | Oakland-Alameda County Stadium (30-22) | 58-47 | |
| » Starters: Jim Bibby vs Vida Blue | First | -- |
| Tuesday, July 31 |
| » Defeated Twins (53-50), 4-3 | Oakland-Alameda County Stadium (31-22) | 59-47 | |
| » Starters: Dick Woodson vs Ken Holtzman | First | -- |
| Wednesday, August 1 |
| » Defeated Twins (53-51), 6-2 | Oakland-Alameda County Stadium (32-22) | 60-47 | Won 2 |
| » Starters: Bert Blyleven vs Catfish Hunter | First | -- |
| Thursday, August 2 |
| » Lost to Twins (54-51), 6-3 | Oakland-Alameda County Stadium (32-23) | 60-48 | |
| » Starters: Joe Decker vs Paul Lindblad | Second | 1 out |
| Friday, August 3 |
| » Defeated Angels (51-55), 2-1 | Anaheim Stadium (2-1) | 61-48 | |
| » Starters: Vida Blue vs Bill Singer | Second | 1 out |
| Future Athletic Blake Stein is born in McComb, MS. |
| Saturday, August 4 |
| » Defeated Angels (51-56), 3-2 | Anaheim Stadium (3-1) | 62-48 | Won 2 |
| » Starters: Ken Holtzman vs Clyde Wright | Second | 1 out |
| Sunday, August 5 |
| » Defeated Angels (51-57), 6-2 | Anaheim Stadium (4-1) | 63-48 | Won 3 |
| » Starters: Darold Knowles vs Rudy May | First | -- |
| Tuesday, August 7 |
| » Defeated Tigers (60-51), 8-4 | Tiger Stadium (1-3) | 64-48 | Won 4 |
| » Starters: Vida Blue vs Mickey Lolich | Second | ½ out |
| » Lost to Tigers (61-51), 2-0 | Tiger Stadium (1-4) | 64-49 | |
| » Starters: Paul Lindblad vs Jim Perry | Second | ½ out |
| Wednesday, August 8 |
| » Lost to Tigers (62-51), 3-2 | Tiger Stadium (1-5) | 64-50 | Lost 2 |
| » Starters: Ken Holtzman vs Woodie Fryman | Second | ½ out |
| Friday, August 10 |
| » Lost to Yankees (64-54), 10-9 | Yankee Stadium (1-3) | 64-51 | Lost 3 |
| » Starters: Darold Knowles vs Pat Dobson | Second | 2 out |
| Saturday, August 11 |
| » Defeated Yankees (64-55), 7-3 | Yankee Stadium (2-3) | 65-51 | |
| » Starters: Vida Blue vs Mel Stottlemyre | Second | 2 out |
| Sunday, August 12 |
| » Defeated Yankees (64-56), 13-12 | Yankee Stadium (3-3) | 66-51 | Won 2 |
| » Starters: Ken Holtzman vs Sam McDowell | Second | 1 out |
| Monday, August 13 |
| » Defeated Red Sox (62-55), 3-1 | Fenway Park (3-1) | 67-51 | Won 3 |
| » Starters: Blue Moon Odom vs Luis Tiant | Second | ½ out |
| Tuesday, August 14 |
| » Defeated Red Sox (62-56), 1-0 | Fenway Park (4-1) | 68-51 | Won 4 |
| » Starters: Darold Knowles vs Bill Lee | Second | ½ out |
| Thursday, August 16 |
| » Defeated Red Sox (62-57), 6-3 | Fenway Park (5-1) | 69-51 | Won 5 |
| » Starters: Vida Blue vs John Curtis | First | -- |
| Friday, August 17 |
| » Defeated Brewers (59-60), 3-2 | Oakland-Alameda County Stadium (33-23) | 70-51 | Won 6 |
| » Starters: Jim Colborn vs Ken Holtzman | First | -- |
| Saturday, August 18 |
| » Defeated Brewers (59-61), 6-3 | Oakland-Alameda County Stadium (34-23) | 71-51 | Won 7 |
| » Starters: Jim Slaton vs Blue Moon Odom | First | -- |
| Sunday, August 19 |
| » Defeated Brewers (59-62), 6-4 | Oakland-Alameda County Stadium (35-23) | 72-51 | Won 8 |
| » Starters: Bill Parsons vs Catfish Hunter | First | -- |
| Monday, August 20 |
| » Defeated Tigers (67-57), 7-2 | Oakland-Alameda County Stadium (36-23) | 73-51 | Won 9 |
| » Starters: Jim Perry vs Vida Blue | First | -- |
| Tuesday, August 21 |
| » Lost to Tigers (68-57), 6-4 | Oakland-Alameda County Stadium (36-24) | 73-52 | |
| » Starters: Woodie Fryman vs Ken Holtzman | First | -- |
| Wednesday, August 22 |
| » Defeated Tigers (68-58), 7-3 | Oakland-Alameda County Stadium (37-24) | 74-52 | |
| » Starters: Joe Coleman vs Blue Moon Odom | First | -- |
| Friday, August 24 |
| » Defeated Yankees (68-62), 5-1 | Oakland-Alameda County Stadium (38-24) | 75-52 | Won 2 |
| » Starters: Doc Medich vs Catfish Hunter | First | -- |
| Saturday, August 25 |
| » Defeated Yankees (68-63), 2-0 | Oakland-Alameda County Stadium (39-24) | 76-52 | Won 3 |
| » Starters: Pat Dobson vs Vida Blue | First | -- |
| Sunday, August 26 |
| » Defeated Yankees (68-64), 1-0 | Oakland-Alameda County Stadium (40-24) | 77-52 | Won 4 |
| » Starters: Mel Stottlemyre vs Ken Holtzman | First | -- |
| Monday, August 27 |
| » Lost to Red Sox (71-58), 5-2 | Oakland-Alameda County Stadium (40-25) | 77-53 | |
| » Starters: Roger Moret vs Blue Moon Odom | First | -- |
| Tuesday, August 28 |
| » Defeated Red Sox (71-59), 6-1 | Oakland-Alameda County Stadium (41-25) | 78-53 | |
| » Starters: Dick Pole vs Catfish Hunter | First | -- |
| Wednesday, August 29 |
| » Lost to Red Sox (72-59), 6-4 | Oakland-Alameda County Stadium (41-26) | 78-54 | |
| » Starters: Bill Lee vs Vida Blue | First | -- |
| Friday, August 31 |
| » Defeated Royals (74-60), 10-7 | Royals Stadium (4-3) | 79-54 | |
| » Starters: Ken Holtzman vs Paul Splittorff | First | -- |
| Saturday, September 1 |
| » Lost to Royals (75-60), 10-9 | Royals Stadium (4-4) | 79-55 | |
| » Starters: Catfish Hunter vs Al Fitzmorris | First | -- |
| » Major-league debuts: Tom Poquette (Royals) |
| Sunday, September 2 |
| » Lost to Royals (76-60), 6-5 | Royals Stadium (4-5) | 79-56 | Lost 2 |
| » Starters: Vida Blue vs Steve Busby | First | -- |
| Monday, September 3 |
| » Lost to Angels (62-70), 3-1 | Anaheim Stadium (4-2) | 79-57 | Lost 3 |
| » Starters: Blue Moon Odom vs Nolan Ryan | First | -- |
| Tuesday, September 4 |
| » Defeated Angels (62-71), 4-3 | Anaheim Stadium (5-2) | 80-57 | |
| » Starters: Ken Holtzman vs Bill Singer | First | -- |
| » Major-league debuts: Dave Chalk (Angels) |
| Wednesday, September 5 |
| » Defeated Angels (62-72), 11-8 | Anaheim Stadium (6-2) | 81-57 | Won 2 |
| » Starters: Catfish Hunter vs Rudy May | First | -- |
| Thursday, September 6 |
| » Defeated Angels (62-73), 6-4 | Anaheim Stadium (7-2) | 82-57 | Won 3 |
| » Starters: Vida Blue vs Clyde Wright | First | -- |
| Friday, September 7 |
| » Lost to Rangers (48-91), 10-8 | Arlington Stadium (4-3) | 82-58 | |
| » Starters: Blue Moon Odom vs David Clyde | First | -- |
| » Major-league debuts: Bill Madlock (Rangers) |
| Saturday, September 8 |
| » Lost to Rangers (49-91), 4-3 | Arlington Stadium (4-4) | 82-59 | Lost 2 |
| » Starters: Ken Holtzman vs Rick Henninger | First | -- |
| Sunday, September 9 |
| » Lost to Rangers (50-91), 5-3 | Arlington Stadium (4-5) | 82-60 | Lost 3 |
| » Starters: Catfish Hunter vs Jim Bibby | First | -- |
| Monday, September 10 |
| » Defeated Royals (78-65), 13-0 | Oakland-Alameda County Stadium (42-26) | 83-60 | |
| » Starters: Steve Busby vs Vida Blue | First | -- |
| Tuesday, September 11 |
| » Defeated Royals (78-66), 3-1 | Oakland-Alameda County Stadium (43-26) | 84-60 | Won 2 |
| » Starters: Gene Garber vs Glenn Abbott | First | -- |
| Wednesday, September 12 |
| » Lost to Royals (79-66), 5-0 | Oakland-Alameda County Stadium (43-27) | 84-61 | |
| » Starters: Paul Splittorff vs Ken Holtzman | First | -- |
| Friday, September 14 |
| » Defeated Rangers (51-94), 5-1 | Oakland-Alameda County Stadium (44-27) | 85-61 | |
| » Starters: Jim Bibby vs Catfish Hunter | First | -- |
| Saturday, September 15 |
| » Defeated Rangers (51-95), 3-1 | Oakland-Alameda County Stadium (45-27) | 86-61 | Won 2 |
| » Starters: Pete Broberg vs Vida Blue | First | -- |
| Sunday, September 16 |
| » Defeated Rangers (51-96), 9-4 | Oakland-Alameda County Stadium (46-27) | 87-61 | Won 3 |
| » Starters: Steve Dunning vs Glenn Abbott | First | -- |
| Monday, September 17 |
| » Defeated Angels (69-78), 3-2 | Oakland-Alameda County Stadium (47-27) | 88-61 | Won 4 |
| » Starters: Rich Hand vs Ken Holtzman | First | -- |
| Tuesday, September 18 |
| » Defeated Angels (69-79), 5-4 | Oakland-Alameda County Stadium (48-27) | 89-61 | Won 5 |
| » Starters: Andy Hassler vs Catfish Hunter | First | -- |
| Wednesday, September 19 |
| » Defeated Twins (73-77), 3-0 | Metropolitan Stadium (2-4) | 90-61 | Won 6 |
| » Starters: Vida Blue vs Joe Decker | First | -- |
| Thursday, September 20 |
| » Lost to Twins (74-77), 4-3 | Metropolitan Stadium (2-5) | 90-62 | |
| » Starters: Blue Moon Odom vs Bill Hands | First | -- |
| » Lost to Twins (75-77), 5-4 | Metropolitan Stadium (2-6) | 90-63 | Lost 2 |
| » Starters: Darold Knowles vs Danny Fife | First | -- |
| Friday, September 21 |
| » Lost to Twins (76-77), 8-3 | Metropolitan Stadium (2-7) | 90-64 | Lost 3 |
| » Starters: Ken Holtzman vs Ray Corbin | First | -- |
| Saturday, September 22 |
| » Defeated White Sox (75-80), 9-3 | Comiskey Park I (5-3) | 91-64 | |
| » Starters: Catfish Hunter vs Stan Bahnsen | First | -- |
| Sunday, September 23 |
| » Defeated White Sox (75-81), 10-5 | Comiskey Park I (6-3) | 92-64 | Won 2 |
| » Starters: Vida Blue vs Wilbur Wood | First | -- |
| Monday, September 24 |
| » Lost to Twins (78-78), 7-6 | Oakland-Alameda County Stadium (48-28) | 92-65 | |
| » Starters: Danny Fife vs Blue Moon Odom | First | -- |
| Tuesday, September 25 |
| » Lost to Twins (79-78), 9-4 | Oakland-Alameda County Stadium (48-29) | 92-66 | Lost 2 |
| » Starters: Ray Corbin vs Chuck Dobson | First | -- |
| Wednesday, September 26 |
| » Lost to Twins (80-78), 4-1 | Oakland-Alameda County Stadium (48-30) | 92-67 | Lost 3 |
| » Starters: Bert Blyleven vs Catfish Hunter | First | -- |
| Friday, September 28 |
| » Defeated White Sox (76-84), 4-1 | Oakland-Alameda County Stadium (49-30) | 93-67 | |
| » Starters: Jim McGlothlin vs Vida Blue | First | -- |
| Saturday, September 29 |
| » Defeated White Sox (76-85), 7-5 | Oakland-Alameda County Stadium (50-30) | 94-67 | Won 2 |
| » Starters: Terry Forster vs Ken Holtzman | First | -- |
| Sunday, September 30 |
| » Lost to White Sox (77-85), 1-0 | Oakland-Alameda County Stadium (50-31) | 94-68 | |
| » Starters: Steve Stone vs Catfish Hunter | First | -- |
| Friday, October 5 |
| Future Athletic Brett Laxton is born in Stratford, NJ. |
| Monday, November 5 |
| Future Athletic Johnny Damon is born in Fort Riley, KS. |
| Thursday, November 29 |
| Former Athletic Tom Hamilton dies in Tyler, TX at the age of 49. |
| Sunday, December 9 |
| Future Athletic Tony Batista is born in Puerto Plata, D.R. |
Game information provided by Retrosheet (www.retrosheet.org) |