| Tuesday, January 11 |
| Future Royal Jermaine Allensworth is born in Anderson, IN. |
| Saturday, April 15 |
| » Defeated White Sox (0-1), 2-1 | Municipal Stadium (1-0) | 1-0 | |
| » Starters: Wilbur Wood vs Dick Drago | First | -- |
| » Major-league debuts: Jorge Orta (White Sox) |
| Sunday, April 16 |
| » Defeated White Sox (0-2), 2-1 | Municipal Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Stan Bahnsen vs Paul Splittorff | First | -- |
| » Defeated White Sox (0-3), 4-3 | Municipal Stadium (3-0) | 3-0 | Won 3 |
| » Starters: Tom Bradley vs Monty Montgomery | First | -- |
| » Major-league debuts: Goose Gossage (White Sox) |
| Tuesday, April 18 |
| » Lost to Athletics (2-1), 3-2 | Oakland-Alameda County Stadium (0-1) | 3-1 | |
| » Starters: Mike Hedlund vs Denny McLain | First | -- |
| Wednesday, April 19 |
| » Lost to Athletics (3-1), 4-0 | Oakland-Alameda County Stadium (0-2) | 3-2 | Lost 2 |
| » Starters: Dick Drago vs Ken Holtzman | Third | 1½ out |
| » Lost to Athletics (4-1), 3-1 | Oakland-Alameda County Stadium (0-3) | 3-3 | Lost 3 |
| » Starters: Bruce DalCanton vs Catfish Hunter | Third | 1½ out |
| Saturday, April 22 |
| » Lost to White Sox (3-3), 1-0 | Comiskey Park I (0-1) | 3-4 | Lost 4 |
| » Starters: Paul Splittorff vs Wilbur Wood | Fifth | 2½ out |
| » Lost to White Sox (4-3), 3-2 | Comiskey Park I (0-2) | 3-5 | Lost 5 |
| » Starters: Monty Montgomery vs Tom Bradley | Fifth | 2½ out |
| Sunday, April 23 |
| » Lost to White Sox (5-3), 3-2 | Comiskey Park I (0-3) | 3-6 | Lost 6 |
| » Starters: Mike Hedlund vs Stan Bahnsen | Fifth | 2½ out |
| Tuesday, April 25 |
| » Defeated Orioles (5-4), 3-0 | Municipal Stadium (4-0) | 4-6 | |
| » Starters: Pat Dobson vs Dick Drago | Fifth | 2½ out |
| Wednesday, April 26 |
| » Defeated Orioles (5-5), 5-3 | Municipal Stadium (5-0) | 5-6 | Won 2 |
| » Starters: Dave McNally vs Bruce DalCanton | Fifth | 2 out |
| Friday, April 28 |
| » Defeated Indians (4-6), 4-0 | Municipal Stadium (6-0) | 6-6 | Won 3 |
| » Starters: Gaylord Perry vs Paul Splittorff | Fifth | 2 out |
| Saturday, April 29 |
| » Lost to Indians (5-6), 3-1 | Municipal Stadium (6-1) | 6-7 | |
| » Starters: Milt Wilcox vs Monty Montgomery | Fourth | 3 out |
| Sunday, April 30 |
| » Lost to Indians (6-6), 5-3 | Municipal Stadium (6-2) | 6-8 | Lost 2 |
| » Starters: Dick Tidrow vs Dick Drago | Fifth | 3½ out |
| Tuesday, May 2 |
| » Defeated Tigers (7-5), 6-3 | Tiger Stadium (1-0) | 7-8 | |
| » Starters: Bruce DalCanton vs Tom Timmermann | Fifth | 3 out |
| Wednesday, May 3 |
| » Lost to Tigers (8-5), 6-1 | Tiger Stadium (1-1) | 7-9 | |
| » Starters: Paul Splittorff vs Mickey Lolich | Fifth | 4 out |
| Friday, May 5 |
| » Lost to Orioles (9-6), 3-2 | Memorial Stadium (0-1) | 7-10 | Lost 2 |
| » Starters: Mike Hedlund vs Jim Palmer | Fifth | 5 out |
| Saturday, May 6 |
| » Defeated Orioles (9-7), 9-1 | Memorial Stadium (1-1) | 8-10 | |
| » Starters: Dick Drago vs Mike Cuellar | Fifth | 5 out |
| » Major-league debuts: Mickey Scott (Orioles) |
| Sunday, May 7 |
| » Lost to Orioles (10-7), 5-4 | Memorial Stadium (1-2) | 8-11 | |
| » Starters: Bruce DalCanton vs Pat Dobson | Fifth | 6 out |
| Tuesday, May 9 |
| » Lost to Indians (11-7), 2-1 | Cleveland Stadium (0-1) | 8-12 | Lost 2 |
| » Starters: Paul Splittorff vs Dick Tidrow | Fifth | 6½ out |
| Wednesday, May 10 |
| » Lost to Indians (12-7), 7-2 | Cleveland Stadium (0-2) | 8-13 | Lost 3 |
| » Starters: Mike Hedlund vs Gaylord Perry | Fifth | 7½ out |
| Saturday, May 13 |
| » Lost to Tigers (12-7), 3-1 | Municipal Stadium (6-3) | 8-14 | Lost 4 |
| » Starters: Mickey Lolich vs Dick Drago | Fifth | 8 out |
| Sunday, May 14 |
| » Lost to Tigers (13-7), 3-2 | Municipal Stadium (6-4) | 8-15 | Lost 5 |
| » Starters: Joe Coleman vs Al Fitzmorris | Sixth | 8½ out |
| » Defeated Tigers (13-8), 8-4 | Municipal Stadium (7-4) | 9-15 | |
| » Starters: Chuck Seelbach vs Paul Splittorff | Sixth | 8½ out |
| Monday, May 15 |
| » Defeated Rangers (10-14), 5-4 | Municipal Stadium (8-4) | 10-15 | Won 2 |
| » Starters: Pete Broberg vs Mike Hedlund | Fifth | 7½ out |
| Tuesday, May 16 |
| » Defeated Rangers (10-15), 5-0 | Municipal Stadium (9-4) | 11-15 | Won 3 |
| » Starters: Rich Hand vs Jim Rooker | Fourth | 6½ out |
| Wednesday, May 17 |
| » Lost to Rangers (11-15), 4-3 | Municipal Stadium (9-5) | 11-16 | |
| » Starters: Dick Bosman vs Dick Drago | Fifth | 7½ out |
| Thursday, May 18 |
| Future Royal Jaime Bluma is born in Beaufort, SC. |
| Friday, May 19 |
| » Defeated Athletics (15-10), 16-1 | Municipal Stadium (10-5) | 12-16 | |
| » Starters: Blue Moon Odom vs Paul Splittorff | Fifth | 6½ out |
| Saturday, May 20 |
| » Lost to Athletics (16-10), 8-5 | Municipal Stadium (10-6) | 12-17 | |
| » Starters: Diego Segui vs Al Fitzmorris | Fifth | 6½ out |
| Sunday, May 21 |
| » Lost to Athletics (17-10), 5-2 | Municipal Stadium (10-7) | 12-18 | Lost 2 |
| » Starters: Ken Holtzman vs Mike Hedlund | Fifth | 7 out |
| Wednesday, May 24 |
| » Lost to Twins (18-11), 1-0 | Municipal Stadium (10-8) | 12-19 | Lost 3 |
| » Starters: Jim Kaat vs Dick Drago | Fifth | 9 out |
| Thursday, May 25 |
| » Defeated Angels (12-22), 5-2 | Anaheim Stadium (1-0) | 13-19 | |
| » Starters: Paul Splittorff vs Rudy May | Fourth | 8½ out |
| Friday, May 26 |
| » Lost to Angels (13-22), 10-5 | Anaheim Stadium (1-1) | 13-20 | |
| » Starters: Jim Rooker vs Nolan Ryan | Fourth | 8½ out |
| Saturday, May 27 |
| » Lost to Angels (14-22), 4-2 | Anaheim Stadium (1-2) | 13-21 | Lost 2 |
| » Starters: Tom Murphy vs Rickey Clark | Sixth | 9 out |
| Sunday, May 28 |
| » Lost to Angels (15-22), 4-2 | Anaheim Stadium (1-3) | 13-22 | Lost 3 |
| » Starters: Dick Drago vs Clyde Wright | Sixth | 10 out |
| Tuesday, May 30 |
| » Lost to Twins (22-12), 3-2 | Metropolitan Stadium (0-1) | 13-23 | Lost 4 |
| » Starters: Paul Splittorff vs Jim Perry | Fifth | 11 out |
| Wednesday, May 31 |
| » Lost to Twins (23-12), 3-2 | Metropolitan Stadium (0-2) | 13-24 | Lost 5 |
| » Starters: Jim Rooker vs Bert Blyleven | Sixth | 12 out |
| Thursday, June 1 |
| » Defeated Twins (23-13), 5-3 | Metropolitan Stadium (1-2) | 14-24 | |
| » Starters: Tom Murphy vs Dick Woodson | Sixth | 11½ out |
| Friday, June 2 |
| » Defeated Red Sox (16-20), 9-1 | Municipal Stadium (11-8) | 15-24 | Won 2 |
| » Starters: Lew Krausse vs Dick Drago | Sixth | 10½ out |
| Saturday, June 3 |
| » Defeated Red Sox (16-21), 10-4 | Municipal Stadium (12-8) | 16-24 | Won 3 |
| » Starters: Marty Pattin vs Paul Splittorff | Fifth | 10½ out |
| Sunday, June 4 |
| » Defeated Red Sox (16-22), 7-5 | Municipal Stadium (13-8) | 17-24 | Won 4 |
| » Starters: Ray Culp vs Jim Rooker | Sixth | 11½ out |
| » Lost to Red Sox (17-22), 4-0 | Municipal Stadium (13-9) | 17-25 | |
| » Starters: John Curtis vs Mike Hedlund | Sixth | 11½ out |
| Tuesday, June 6 |
| » Defeated Brewers (15-24), 4-2 | Municipal Stadium (14-9) | 18-25 | |
| » Starters: Ken Brett vs Tom Murphy | Sixth | 12 out |
| Wednesday, June 7 |
| » Defeated Brewers (15-25), 5-4 | Municipal Stadium (15-9) | 19-25 | Won 2 |
| » Starters: Jim Lonborg vs Dick Drago | Fifth | 12 out |
| Thursday, June 8 |
| » Lost to Brewers (16-25), 4-3 | Municipal Stadium (15-10) | 19-26 | |
| » Starters: Bill Parsons vs Paul Splittorff | Sixth | 12½ out |
| Friday, June 9 |
| » Defeated Yankees (19-27), 1-0 | Municipal Stadium (16-10) | 20-26 | |
| » Starters: Mike Kekich vs Jim Rooker | Fifth | 12½ out |
| Saturday, June 10 |
| » Lost to Yankees (20-27), 8-4 | Municipal Stadium (16-11) | 20-27 | |
| » Starters: Fritz Peterson vs Tom Murphy | Fifth | 13½ out |
| Sunday, June 11 |
| » Defeated Yankees (20-28), 1-0 | Municipal Stadium (17-11) | 21-27 | |
| » Starters: Steve Kline vs Dick Drago | Fifth | 12½ out |
| Tuesday, June 13 |
| » Defeated Red Sox (20-25), 4-2 | Fenway Park (1-0) | 22-27 | Won 2 |
| » Starters: Paul Splittorff vs Marty Pattin | Fifth | 11 out |
| Future Royal Darrell May is born in San Bernardino, CA. |
| Wednesday, June 14 |
| » Lost to Red Sox (21-25), 11-3 | Fenway Park (1-1) | 22-28 | |
| » Starters: Jim Rooker vs John Curtis | Fifth | 11 out |
| Thursday, June 15 |
| » Defeated Red Sox (21-26), 13-9 | Fenway Park (2-1) | 23-28 | |
| » Starters: Tom Murphy vs Sonny Siebert | Fifth | 10½ out |
| » Major-league debuts: Don Newhauser (Red Sox) |
| Friday, June 16 |
| » Defeated Brewers (16-33), 3-2 | County Stadium (1-0) | 24-28 | Won 2 |
| » Starters: Dick Drago vs Jim Lonborg | Fifth | 10½ out |
| Saturday, June 17 |
| » Defeated Brewers (16-34), 6-3 | County Stadium (2-0) | 25-28 | Won 3 |
| » Starters: Paul Splittorff vs Bill Parsons | Fourth | 10½ out |
| Sunday, June 18 |
| » Lost to Brewers (17-34), 3-0 | County Stadium (2-1) | 25-29 | |
| » Starters: Jim Rooker vs Skip Lockwood | Fourth | 11½ out |
| Tuesday, June 20 |
| » Lost to Yankees (25-29), 4-2 | Yankee Stadium (0-1) | 25-30 | Lost 2 |
| » Starters: Dick Drago vs Mike Kekich | Fourth | 13 out |
| Friday, June 23 |
| » Defeated Twins (30-25), 5-0 | Municipal Stadium (18-11) | 26-30 | |
| » Starters: Jim Perry vs Paul Splittorff | Fifth | 11½ out |
| Saturday, June 24 |
| » Lost to Twins (31-25), 4-1 | Municipal Stadium (18-12) | 26-31 | |
| » Starters: Jim Kaat vs Jim Rooker | Fifth | 11½ out |
| Sunday, June 25 |
| » Lost to Twins (32-25), 5-3 | Municipal Stadium (18-13) | 26-32 | Lost 2 |
| » Starters: Bert Blyleven vs Dick Drago | Fifth | 12½ out |
| » Defeated Twins (32-26), 8-3 | Municipal Stadium (19-13) | 27-32 | |
| » Starters: Dick Woodson vs Tom Murphy | Fifth | 12½ out |
| Monday, June 26 |
| » Defeated White Sox (36-25), 4-1 | Municipal Stadium (20-13) | 28-32 | Won 2 |
| » Starters: Wilbur Wood vs Bruce DalCanton | Fourth | 12½ out |
| Tuesday, June 27 |
| » Defeated White Sox (36-26), 6-4 | Municipal Stadium (21-13) | 29-32 | Won 3 |
| » Starters: Stan Bahnsen vs Paul Splittorff | Fourth | 12½ out |
| Thursday, June 29 |
| » Defeated Twins (34-28), 5-3 | Metropolitan Stadium (2-2) | 30-32 | Won 4 |
| » Starters: Dick Drago vs Bert Blyleven | Fourth | 11 out |
| » Defeated Twins (34-29), 12-4 | Metropolitan Stadium (3-2) | 31-32 | Won 5 |
| » Starters: Mike Hedlund vs Dick Woodson | Fourth | 11 out |
| Friday, June 30 |
| » Lost to Twins (35-29), 2-0 | Metropolitan Stadium (3-3) | 31-33 | |
| » Starters: Roger Nelson vs Ray Corbin | Fourth | 11 out |
| Saturday, July 1 |
| » Defeated Rangers (27-39), 3-2 | Municipal Stadium (22-13) | 32-33 | |
| » Starters: Bill Gogolewski vs Paul Splittorff | Fourth | 10 out |
| Sunday, July 2 |
| » Lost to Rangers (28-39), 7-5 | Municipal Stadium (22-14) | 32-34 | |
| » Starters: Dick Bosman vs Bruce DalCanton | Fourth | 10½ out |
| » Defeated Rangers (28-40), 8-3 | Municipal Stadium (23-14) | 33-34 | |
| » Starters: Pete Broberg vs Jim Rooker | Fourth | 10½ out |
| Monday, July 3 |
| » Lost to Rangers (29-40), 2-1 | Municipal Stadium (23-15) | 33-35 | |
| » Starters: Mike Paul vs Dick Drago | Fourth | 11½ out |
| Tuesday, July 4 |
| » Defeated Tigers (37-31), 1-0 | Municipal Stadium (24-15) | 34-35 | |
| » Starters: Bill Slayback vs Roger Nelson | Fourth | 11½ out |
| Wednesday, July 5 |
| » Defeated Tigers (37-32), 8-2 | Municipal Stadium (25-15) | 35-35 | Won 2 |
| » Starters: Mickey Lolich vs Paul Splittorff | Fourth | 10½ out |
| Thursday, July 6 |
| » Lost to Tigers (38-32), 7-0 | Municipal Stadium (25-16) | 35-36 | |
| » Starters: Joe Coleman vs Jim Rooker | Fourth | 10½ out |
| Friday, July 7 |
| » Defeated Indians (30-40), 6-3 | Cleveland Stadium (1-2) | 36-36 | |
| » Starters: Dick Drago vs Milt Wilcox | Fourth | 9½ out |
| Saturday, July 8 |
| » Lost to Indians (31-40), 2-1 | Cleveland Stadium (1-3) | 36-37 | |
| » Starters: Roger Nelson vs Mike Kilkenny | Fourth | 10½ out |
| Sunday, July 9 |
| » Defeated Indians (31-41), 6-4 | Cleveland Stadium (2-3) | 37-37 | |
| » Starters: Paul Splittorff vs Vince Colbert | Third | 10 out |
| » Defeated Indians (31-42), 8-5 | Cleveland Stadium (3-3) | 38-37 | Won 2 |
| » Starters: Mike Hedlund vs Ed Farmer | Third | 10 out |
| Monday, July 10 |
| » Defeated Orioles (40-35), 3-2 | Memorial Stadium (2-2) | 39-37 | Won 3 |
| » Starters: Bruce DalCanton vs Mike Cuellar | Fourth | 9 out |
| Tuesday, July 11 |
| » Lost to Orioles (41-35), 2-1 | Memorial Stadium (2-3) | 39-38 | |
| » Starters: Dick Drago vs Jim Palmer | Fourth | 9 out |
| Wednesday, July 12 |
| » Defeated Orioles (41-36), 11-4 | Memorial Stadium (3-3) | 40-38 | |
| » Starters: Roger Nelson vs Pat Dobson | Third | 8 out |
| Thursday, July 13 |
| » Lost to Tigers (44-34), 6-4 | Tiger Stadium (1-2) | 40-39 | |
| » Starters: Paul Splittorff vs Mickey Lolich | Fourth | 8½ out |
| Friday, July 14 |
| » Defeated Tigers (44-35), 1-0 | Tiger Stadium (2-2) | 41-39 | |
| » Starters: Bruce DalCanton vs Joe Coleman | Fourth | 9 out |
| Saturday, July 15 |
| » Lost to Tigers (45-35), 5-3 | Tiger Stadium (2-3) | 41-40 | |
| » Starters: Dick Drago vs Tom Timmermann | Fourth | 10 out |
| Future Royal Wilson Delgado is born in San Cristobal, D.R. |
| Sunday, July 16 |
| » Lost to Tigers (46-35), 2-0 | Tiger Stadium (2-4) | 41-41 | Lost 2 |
| » Starters: Roger Nelson vs Bill Slayback | Fourth | 11 out |
| Tuesday, July 18 |
| » Defeated Indians (34-47), 6-5 | Municipal Stadium (26-16) | 42-41 | |
| » Starters: Milt Wilcox vs Paul Splittorff | Fourth | 10 out |
| » Defeated Indians (34-48), 11-8 | Municipal Stadium (27-16) | 43-41 | Won 2 |
| » Starters: Vince Colbert vs Bruce DalCanton | Fourth | 10 out |
| Wednesday, July 19 |
| » Lost to Indians (35-48), 6-1 | Municipal Stadium (27-17) | 43-42 | |
| » Starters: Gaylord Perry vs Dick Drago | Fourth | 11 out |
| Thursday, July 20 |
| » Lost to Orioles (48-37), 8-5 | Municipal Stadium (27-18) | 43-43 | Lost 2 |
| » Starters: Jim Palmer vs Roger Nelson | Fourth | 10½ out |
| Friday, July 21 |
| » Lost to Orioles (49-37), 7-6 | Municipal Stadium (27-19) | 43-44 | Lost 3 |
| » Starters: Pat Dobson vs Bruce DalCanton | Fourth | 10½ out |
| Saturday, July 22 |
| » Defeated Orioles (49-38), 8-5 | Municipal Stadium (28-19) | 44-44 | |
| » Starters: Dave McNally vs Paul Splittorff | Fourth | 10 out |
| Sunday, July 23 |
| » Lost to Orioles (50-38), 8-4 | Municipal Stadium (28-20) | 44-45 | |
| » Starters: Mike Cuellar vs Dick Drago | Fourth | 11 out |
| Thursday, July 27 |
| » Lost to White Sox (50-41), 7-3 | Comiskey Park I (0-4) | 44-46 | Lost 2 |
| » Starters: Paul Splittorff vs Wilbur Wood | Fourth | 11½ out |
| » Defeated White Sox (50-42), 3-0 | Comiskey Park I (1-4) | 45-46 | |
| » Starters: Roger Nelson vs Stan Bahnsen | Fourth | 11½ out |
| Friday, July 28 |
| » Lost to White Sox (51-42), 5-0 | Comiskey Park I (1-5) | 45-47 | |
| » Starters: Dick Drago vs Tom Bradley | Fourth | 11½ out |
| Saturday, July 29 |
| » Lost to White Sox (52-42), 4-3 | Comiskey Park I (1-6) | 45-48 | Lost 2 |
| » Starters: Bruce DalCanton vs Dave Lemonds | Fourth | 12½ out |
| Sunday, July 30 |
| » Lost to Angels (44-52), 4-3 | Anaheim Stadium (1-4) | 45-49 | Lost 3 |
| » Starters: Mike Hedlund vs Andy Messersmith | Fourth | 12 out |
| Monday, July 31 |
| » Defeated Angels (44-53), 1-0 | Anaheim Stadium (2-4) | 46-49 | |
| » Starters: Roger Nelson vs Nolan Ryan | Fourth | 12 out |
| Tuesday, August 1 |
| » Lost to Athletics (60-38), 4-0 | Oakland-Alameda County Stadium (0-4) | 46-50 | |
| » Starters: Paul Splittorff vs Ken Holtzman | Fourth | 13 out |
| Wednesday, August 2 |
| » Lost to Athletics (61-38), 5-0 | Oakland-Alameda County Stadium (0-5) | 46-51 | Lost 2 |
| » Starters: Dick Drago vs Catfish Hunter | Fourth | 14 out |
| Friday, August 4 |
| » Lost to Angels (45-55), 6-5 | Municipal Stadium (28-21) | 46-52 | Lost 3 |
| » Starters: Nolan Ryan vs Bruce DalCanton | Fourth | 14 out |
| Saturday, August 5 |
| » Defeated Angels (45-56), 2-1 | Municipal Stadium (29-21) | 47-52 | |
| » Starters: Rudy May vs Mike Hedlund | Fourth | 13 out |
| Sunday, August 6 |
| » Lost to Angels (46-56), 4-3 | Municipal Stadium (29-22) | 47-53 | |
| » Starters: Steve Barber vs Roger Nelson | Fourth | 14 out |
| » Lost to Angels (47-56), 3-2 | Municipal Stadium (29-23) | 47-54 | Lost 2 |
| » Starters: Clyde Wright vs Paul Splittorff | Fourth | 14 out |
| Monday, August 7 |
| » Defeated Athletics (62-42), 4-2 | Municipal Stadium (30-23) | 48-54 | |
| » Starters: Catfish Hunter vs Dick Drago | Fourth | 13 out |
| Tuesday, August 8 |
| » Defeated Athletics (62-43), 4-3 | Municipal Stadium (31-23) | 49-54 | Won 2 |
| » Starters: Blue Moon Odom vs Bruce DalCanton | Fourth | 12 out |
| Wednesday, August 9 |
| » Defeated Athletics (62-44), 5-2 | Municipal Stadium (32-23) | 50-54 | Won 3 |
| » Starters: Vida Blue vs Mike Hedlund | Fourth | 11 out |
| Friday, August 11 |
| » Defeated Rangers (42-65), 2-0 | Arlington Stadium (1-0) | 51-54 | Won 4 |
| » Starters: Roger Nelson vs Rich Hand | Fourth | 10½ out |
| Saturday, August 12 |
| » Lost to Rangers (43-65), 3-0 | Arlington Stadium (1-1) | 51-55 | |
| » Starters: Paul Splittorff vs Mike Paul | Fourth | 10½ out |
| Sunday, August 13 |
| » Lost to Rangers (44-65), 13-4 | Arlington Stadium (1-2) | 51-56 | Lost 2 |
| » Starters: Dick Drago vs Dick Bosman | Fourth | 11½ out |
| Monday, August 14 |
| » Defeated Yankees (58-51), 3-0 | Municipal Stadium (33-23) | 52-56 | |
| » Starters: Steve Kline vs Bruce DalCanton | Fourth | 11½ out |
| Tuesday, August 15 |
| » Defeated Yankees (58-52), 7-6 | Municipal Stadium (34-23) | 53-56 | Won 2 |
| » Starters: Mike Kekich vs Mike Hedlund | Fourth | 11 out |
| Wednesday, August 16 |
| » Defeated Yankees (58-53), 3-2 | Municipal Stadium (35-23) | 54-56 | Won 3 |
| » Starters: Fritz Peterson vs Roger Nelson | Fourth | 11 out |
| Friday, August 18 |
| » Lost to Brewers (44-69), 7-2 | Municipal Stadium (35-24) | 54-57 | |
| » Starters: Jim Lonborg vs Paul Splittorff | Fourth | 12 out |
| Saturday, August 19 |
| » Defeated Brewers (44-70), 2-1 | Municipal Stadium (36-24) | 55-57 | |
| » Starters: Skip Lockwood vs Dick Drago | Fourth | 11 out |
| Future Royal Jed Hansen is born in Tacoma, WA. |
| Sunday, August 20 |
| » Lost to Brewers (45-70), 2-1 | Municipal Stadium (36-25) | 55-58 | |
| » Starters: Jim Colborn vs Bruce DalCanton | Third | 11 out |
| Tuesday, August 22 |
| » Lost to Red Sox (59-56), 10-7 | Municipal Stadium (36-26) | 55-59 | Lost 2 |
| » Starters: Marty Pattin vs Mike Hedlund | Fourth | 12½ out |
| Wednesday, August 23 |
| » Defeated Red Sox (59-57), 3-0 | Municipal Stadium (37-26) | 56-59 | |
| » Starters: Sonny Siebert vs Roger Nelson | Fourth | 12 out |
| Friday, August 25 |
| » Lost to Yankees (61-56), 4-1 | Yankee Stadium (0-2) | 56-60 | |
| » Starters: Paul Splittorff vs Steve Kline | Fourth | 12 out |
| » Defeated Yankees (61-57), 5-1 | Yankee Stadium (1-2) | 57-60 | |
| » Starters: Mike Jackson vs Mike Kekich | Fourth | 12 out |
| Saturday, August 26 |
| » Defeated Yankees (61-58), 6-3 | Yankee Stadium (2-2) | 58-60 | Won 2 |
| » Starters: Dick Drago vs Rob Gardner | Fourth | 11½ out |
| Sunday, August 27 |
| » Lost to Yankees (62-58), 7-6 | Yankee Stadium (2-3) | 58-61 | |
| » Starters: Bruce DalCanton vs Mel Stottlemyre | Fourth | 12 out |
| » Lost to Yankees (63-58), 9-8 | Yankee Stadium (2-4) | 58-62 | Lost 2 |
| » Starters: Mike Hedlund vs Fritz Peterson | Fourth | 12 out |
| Monday, August 28 |
| Future Royal Jay Witasick is born in Baltimore, MD. |
| Tuesday, August 29 |
| » Defeated Brewers (48-74), 6-4 | County Stadium (3-1) | 59-62 | |
| » Starters: Roger Nelson vs Gary Ryerson | Fourth | 12 out |
| Wednesday, August 30 |
| » Defeated Brewers (48-75), 6-2 | County Stadium (4-1) | 60-62 | Won 2 |
| » Starters: Paul Splittorff vs Jim Lonborg | Fourth | 12 out |
| Thursday, August 31 |
| » Lost to Brewers (49-75), 7-3 | County Stadium (4-2) | 60-63 | |
| » Starters: Mike Jackson vs Skip Lockwood | Fourth | 12½ out |
| Friday, September 1 |
| » Lost to Red Sox (65-58), 1-0 | Fenway Park (2-2) | 60-64 | Lost 2 |
| » Starters: Dick Drago vs Marty Pattin | Fourth | 13½ out |
| » Major-league debuts: Jim Wohlford (Royals) |
| Saturday, September 2 |
| » Lost to Red Sox (66-58), 5-3 | Fenway Park (2-3) | 60-65 | Lost 3 |
| » Starters: Mike Hedlund vs Sonny Siebert | Fourth | 13½ out |
| Monday, September 4 |
| » Defeated Rangers (50-79), 4-3 | Arlington Stadium (2-2) | 61-65 | |
| » Starters: Roger Nelson vs Don Stanhouse | Fourth | 13½ out |
| Tuesday, September 5 |
| » Defeated Rangers (50-80), 7-2 | Arlington Stadium (3-2) | 62-65 | Won 2 |
| » Starters: Paul Splittorff vs Rich Hand | Fourth | 13 out |
| Wednesday, September 6 |
| » Lost to Angels (61-69), 3-1 | Municipal Stadium (37-27) | 62-66 | |
| » Starters: Rudy May vs Mike Jackson | Fourth | 14 out |
| » Major-league debuts: Doug Howard (Angels) |
| Thursday, September 7 |
| » Defeated Angels (61-70), 6-0 | Municipal Stadium (38-27) | 63-66 | |
| » Starters: Andy Messersmith vs Monty Montgomery | Fourth | 13 out |
| Friday, September 8 |
| » Defeated Twins (66-64), 5-0 | Municipal Stadium (39-27) | 64-66 | Won 2 |
| » Starters: Bert Blyleven vs Tom Murphy | Fourth | 12½ out |
| » Defeated Twins (66-65), 3-2 | Municipal Stadium (40-27) | 65-66 | Won 3 |
| » Starters: Ray Corbin vs Steve Busby | Fourth | 12½ out |
| » Major-league debuts: Steve Busby (Royals) |
| Saturday, September 9 |
| » Lost to Twins (67-65), 3-2 | Municipal Stadium (40-28) | 65-67 | |
| » Starters: Dave Goltz vs Roger Nelson | Fourth | 12½ out |
| Sunday, September 10 |
| » Defeated Twins (67-66), 3-1 | Municipal Stadium (41-28) | 66-67 | |
| » Starters: Dick Woodson vs Dick Drago | Fourth | 12½ out |
| » Major-league debuts: Mike Adams (Twins) |
| Monday, September 11 |
| » Lost to White Sox (77-59), 2-1 | Municipal Stadium (41-29) | 66-68 | |
| » Starters: Tom Bradley vs Paul Splittorff | Fourth | 12 out |
| Tuesday, September 12 |
| » Lost to White Sox (78-59), 6-0 | Municipal Stadium (41-30) | 66-69 | Lost 2 |
| » Starters: Stan Bahnsen vs Monty Montgomery | Fourth | 13 out |
| Wednesday, September 13 |
| » Defeated White Sox (78-60), 6-4 | Municipal Stadium (42-30) | 67-69 | |
| » Starters: Wilbur Wood vs Steve Busby | Fourth | 13 out |
| Future Royal Chan Perry is born in Live Oak, FL. |
| Friday, September 15 |
| » Lost to Twins (70-68), 4-3 | Metropolitan Stadium (3-4) | 67-70 | |
| » Starters: Roger Nelson vs Dick Woodson | Fourth | 14 out |
| Saturday, September 16 |
| » Lost to Twins (71-68), 11-1 | Metropolitan Stadium (3-5) | 67-71 | Lost 2 |
| » Starters: Dick Drago vs Bert Blyleven | Fourth | 15 out |
| Sunday, September 17 |
| » Defeated Twins (71-69), 10-6 | Metropolitan Stadium (4-5) | 68-71 | |
| » Starters: Paul Splittorff vs Jim Perry | Fourth | 15 out |
| Tuesday, September 19 |
| » Defeated Angels (67-75), 7-2 | Anaheim Stadium (3-4) | 69-71 | Won 2 |
| » Starters: Monty Montgomery vs Clyde Wright | Fourth | 14 out |
| Wednesday, September 20 |
| » Defeated Angels (67-76), 9-2 | Anaheim Stadium (4-4) | 70-71 | Won 3 |
| » Starters: Steve Busby vs Rudy May | Fourth | 14 out |
| Thursday, September 21 |
| » Lost to Angels (68-76), 4-2 | Anaheim Stadium (4-5) | 70-72 | |
| » Starters: Roger Nelson vs Nolan Ryan | Fourth | 14½ out |
| Friday, September 22 |
| » Defeated Athletics (85-59), 5-3 | Oakland-Alameda County Stadium (1-5) | 71-72 | |
| » Starters: Dick Drago vs Vida Blue | Fourth | 13½ out |
| Saturday, September 23 |
| » Lost to Athletics (86-59), 2-1 | Oakland-Alameda County Stadium (1-6) | 71-73 | |
| » Starters: Paul Splittorff vs Catfish Hunter | Fourth | 14½ out |
| Sunday, September 24 |
| » Defeated Athletics (86-60), 4-2 | Oakland-Alameda County Stadium (2-6) | 72-73 | |
| » Starters: Monty Montgomery vs Blue Moon Odom | Fourth | 14½ out |
| » Lost to Athletics (87-60), 2-1 | Oakland-Alameda County Stadium (2-7) | 72-74 | |
| » Starters: Tom Murphy vs Dave Hamilton | Fourth | 14½ out |
| Tuesday, September 26 |
| » Defeated White Sox (83-64), 2-1 | Comiskey Park I (2-6) | 73-74 | |
| » Starters: Steve Busby vs Stan Bahnsen | Fourth | 14 out |
| Wednesday, September 27 |
| » Defeated White Sox (83-65), 4-2 | Comiskey Park I (3-6) | 74-74 | Won 2 |
| » Starters: Roger Nelson vs Wilbur Wood | Fourth | 14½ out |
| Thursday, September 28 |
| » Lost to Red Sox (82-67), 3-1 | Fenway Park (2-4) | 74-75 | |
| » Starters: Dick Drago vs John Curtis | Fourth | 15½ out |
| Friday, September 29 |
| » Defeated Athletics (90-61), 9-2 | Municipal Stadium (43-30) | 75-75 | |
| » Starters: Vida Blue vs Paul Splittorff | Fourth | 14½ out |
| Saturday, September 30 |
| » Lost to Athletics (91-61), 10-5 | Municipal Stadium (43-31) | 75-76 | |
| » Starters: Joe Horlen vs Monty Montgomery | Fourth | 15½ out |
| Sunday, October 1 |
| » Lost to Athletics (92-61), 4-2 | Municipal Stadium (43-32) | 75-77 | Lost 2 |
| » Starters: Ken Holtzman vs Tom Murphy | Fourth | 16½ out |
| Tuesday, October 3 |
| » Lost to Rangers (54-99), 3-0 | Municipal Stadium (43-33) | 75-78 | Lost 3 |
| » Starters: Mike Paul vs Steve Busby | Fourth | 16½ out |
| Wednesday, October 4 |
| » Defeated Rangers (54-100), 4-0 | Municipal Stadium (44-33) | 76-78 | |
| » Starters: Don Stanhouse vs Roger Nelson | Fourth | 16½ out |
| Thursday, October 5 |
| Future Royal Yamil Benitez is born in San Juan, P.R. Future Royal Aaron Guiel is born in Vancouver, BC. |
| Saturday, November 11 |
| Future Royal Danny Rios is born in Madrid, Spain. |
Game information provided by Retrosheet (www.retrosheet.org) |