| Wednesday, February 3 |
| Future Twin Scott Klingenbeck is born in Cincinnati, OH. |
| Friday, March 12 |
| Future Twin Greg Hansell is born in Bellflower, CA. |
| Tuesday, April 6 |
| » Lost to Brewers (1-0), 7-2 | Metropolitan Stadium (0-1) | 0-1 | |
| » Starters: Marty Pattin vs Jim Perry | Third | 1 out |
| » Major-league debuts: Steve Braun and Ray Corbin (Twins) |
| Wednesday, April 7 |
| » Defeated Brewers (1-1), 4-0 | Metropolitan Stadium (1-1) | 1-1 | |
| » Starters: Lew Krausse vs Bert Blyleven | Second | 1 out |
| Friday, April 9 |
| » Lost to White Sox (3-0), 3-2 | Comiskey Park I (0-1) | 1-2 | |
| » Starters: Tom Hall vs Tom Bradley | Fourth | 2 out |
| Saturday, April 10 |
| » Defeated White Sox (3-1), 5-3 | Comiskey Park I (1-1) | 2-2 | |
| » Starters: Jim Perry vs Tommy John | Third | 1 out |
| Sunday, April 11 |
| » Defeated White Sox (3-2), 6-0 | Comiskey Park I (2-1) | 3-2 | Won 2 |
| » Starters: Jim Kaat vs Bart Johnson | Second | ½ out |
| » Major-league debuts: Terry Forster (White Sox) |
| Monday, April 12 |
| » Defeated Royals (3-4), 2-0 | Municipal Stadium (1-0) | 4-2 | Won 3 |
| » Starters: Bert Blyleven vs Dick Drago | First | -- |
| Tuesday, April 13 |
| » Lost to Royals (4-4), 5-3 | Municipal Stadium (1-1) | 4-3 | |
| » Starters: Steve Barber vs Mike Hedlund | First | -- |
| Wednesday, April 14 |
| » Lost to Athletics (5-4), 6-1 | Metropolitan Stadium (1-2) | 4-4 | Lost 2 |
| » Starters: Diego Segui vs Tom Hall | Third | ½ out |
| Thursday, April 15 |
| » Lost to Athletics (6-4), 4-3 | Metropolitan Stadium (1-3) | 4-5 | Lost 3 |
| » Starters: Catfish Hunter vs Jim Kaat | Fourth | 1½ out |
| Friday, April 16 |
| » Lost to Angels (6-4), 4-1 | Metropolitan Stadium (1-4) | 4-6 | Lost 4 |
| » Starters: Rudy May vs Jim Perry | Fourth | 2½ out |
| Saturday, April 17 |
| » Lost to Angels (7-4), 4-3 | Metropolitan Stadium (1-5) | 4-7 | Lost 5 |
| » Starters: Andy Messersmith vs Bert Blyleven | Fifth | 3 out |
| Sunday, April 18 |
| » Lost to Angels (8-4), 5-4 | Metropolitan Stadium (1-6) | 4-8 | Lost 6 |
| » Starters: Clyde Wright vs Tom Hall | Fifth | 4 out |
| Monday, April 19 |
| » Defeated Royals (6-8), 9-8 | Metropolitan Stadium (2-6) | 5-8 | |
| » Starters: Jim Rooker vs Jim Kaat | Fifth | 3½ out |
| Tuesday, April 20 |
| » Defeated Royals (6-9), 5-4 | Metropolitan Stadium (3-6) | 6-8 | Won 2 |
| » Starters: Bruce DalCanton vs Jim Perry | Fourth | 3½ out |
| Friday, April 23 |
| » Lost to Yankees (6-8), 7-3 | Yankee Stadium (0-1) | 6-9 | |
| » Starters: Bert Blyleven vs Steve Kline | Fifth | 5½ out |
| Saturday, April 24 |
| » Defeated Yankees (6-9), 11-8 | Yankee Stadium (1-1) | 7-9 | |
| » Starters: Tom Hall vs Stan Bahnsen | Fifth | 5½ out |
| Sunday, April 25 |
| » Defeated Yankees (6-10), 8-0 | Yankee Stadium (2-1) | 8-9 | Won 2 |
| » Starters: Jim Kaat vs Fritz Peterson | Third | 4½ out |
| Monday, April 26 |
| » Defeated Senators (10-8), 7-2 | Robert F. Kennedy Stadium (1-0) | 9-9 | Won 3 |
| » Starters: Jim Perry vs Jim Shellenback | Third | 4½ out |
| Tuesday, April 27 |
| » Lost to Senators (11-8), 2-0 | Robert F. Kennedy Stadium (1-1) | 9-10 | |
| » Starters: Bert Blyleven vs Denny McLain | Fourth | 4½ out |
| Wednesday, April 28 |
| » Lost to Senators (12-8), 4-3 | Robert F. Kennedy Stadium (1-2) | 9-11 | Lost 2 |
| » Starters: Tom Hall vs Casey Cox | Fourth | 5½ out |
| Friday, April 30 |
| » Lost to Red Sox (12-7), 4-3 | Fenway Park (0-1) | 9-12 | Lost 3 |
| » Starters: Jim Kaat vs Mike Nagy | Fourth | 6 out |
| Saturday, May 1 |
| » Defeated Red Sox (12-8), 7-3 | Fenway Park (1-1) | 10-12 | |
| » Starters: Jim Perry vs Gary Peters | Fourth | 5 out |
| Sunday, May 2 |
| » Lost to Red Sox (13-8), 1-0 | Fenway Park (1-2) | 10-13 | |
| » Starters: Bert Blyleven vs Ray Culp | Fifth | 6 out |
| » Lost to Red Sox (14-8), 9-8 | Fenway Park (1-3) | 10-14 | Lost 2 |
| » Starters: Steve Barber vs Sonny Siebert | Fifth | 6 out |
| Tuesday, May 4 |
| » Defeated Yankees (10-12), 6-5 | Metropolitan Stadium (4-6) | 11-14 | |
| » Starters: Steve Kline vs Jim Kaat | Fourth | 5 out |
| Wednesday, May 5 |
| » Defeated Yankees (10-13), 5-3 | Metropolitan Stadium (5-6) | 12-14 | Won 2 |
| » Starters: Stan Bahnsen vs Jim Perry | Third | 5 out |
| Thursday, May 6 |
| » Defeated Yankees (10-14), 5-3 | Metropolitan Stadium (6-6) | 13-14 | Won 3 |
| » Starters: Mel Stottlemyre vs Tom Hall | Fourth | 4½ out |
| Friday, May 7 |
| » Lost to Senators (13-14), 6-5 | Metropolitan Stadium (6-7) | 13-15 | |
| » Starters: Casey Cox vs Bert Blyleven | Fourth | 5 out |
| Saturday, May 8 |
| » Defeated Senators (13-15), 9-2 | Metropolitan Stadium (7-7) | 14-15 | |
| » Starters: Dick Bosman vs Jim Kaat | Fourth | 4½ out |
| Sunday, May 9 |
| » Defeated Senators (13-16), 6-5 | Metropolitan Stadium (8-7) | 15-15 | Won 2 |
| » Starters: Denny McLain vs Jim Perry | Fourth | 5 out |
| Tuesday, May 11 |
| » Lost to Red Sox (19-9), 5-4 | Metropolitan Stadium (8-8) | 15-16 | |
| » Starters: Gary Peters vs Tom Hall | Fourth | 5 out |
| Wednesday, May 12 |
| » Defeated Red Sox (19-10), 1-0 | Metropolitan Stadium (9-8) | 16-16 | |
| » Starters: Ray Culp vs Bert Blyleven | Second | 5 out |
| Friday, May 14 |
| » Defeated White Sox (12-19), 4-3 | Metropolitan Stadium (10-8) | 17-16 | Won 2 |
| » Starters: Wilbur Wood vs Jim Kaat | Second | 5½ out |
| Saturday, May 15 |
| » Lost to White Sox (13-19), 8-2 | Metropolitan Stadium (10-9) | 17-17 | |
| » Starters: Bart Johnson vs Jim Perry | Second | 5½ out |
| Sunday, May 16 |
| » Defeated White Sox (13-20), 6-2 | Metropolitan Stadium (11-9) | 18-17 | |
| » Starters: Tom Bradley vs Pete Hamm | Second | 5 out |
| Monday, May 17 |
| » Defeated Angels (18-20), 3-2 | Anaheim Stadium (1-0) | 19-17 | Won 2 |
| » Starters: Bert Blyleven vs Rudy May | Second | 4½ out |
| Tuesday, May 18 |
| » Lost to Angels (19-20), 3-1 | Anaheim Stadium (1-1) | 19-18 | |
| » Starters: Jim Kaat vs Tom Murphy | Second | 5½ out |
| Future Twin Rich Garces is born in Maracay, Venezuela. |
| Wednesday, May 19 |
| » Defeated Angels (19-21), 12-6 | Anaheim Stadium (2-1) | 20-18 | |
| » Starters: Jim Perry vs Andy Messersmith | Second | 5½ out |
| » Major-league debuts: Jim Strickland (Twins) |
| Thursday, May 20 |
| » Lost to Angels (20-21), 1-0 | Anaheim Stadium (2-2) | 20-19 | |
| » Starters: Pete Hamm vs Clyde Wright | Second | 6½ out |
| Friday, May 21 |
| » Defeated Athletics (28-15), 10-1 | Oakland-Alameda County Stadium (1-0) | 21-19 | |
| » Starters: Bert Blyleven vs Blue Moon Odom | Second | 5½ out |
| Saturday, May 22 |
| » Lost to Athletics (29-15), 5-1 | Oakland-Alameda County Stadium (1-1) | 21-20 | |
| » Starters: Jim Kaat vs Catfish Hunter | Second | 6½ out |
| Sunday, May 23 |
| » Lost to Athletics (30-15), 3-1 | Oakland-Alameda County Stadium (1-2) | 21-21 | Lost 2 |
| » Starters: Jim Perry vs Vida Blue | Second | 7½ out |
| Tuesday, May 25 |
| » Defeated Brewers (16-22), 8-5 | County Stadium (1-0) | 22-21 | |
| » Starters: Pete Hamm vs Lew Krausse | Second | 7½ out |
| Wednesday, May 26 |
| » Defeated Brewers (16-23), 4-1 | County Stadium (2-0) | 23-21 | Won 2 |
| » Starters: Bert Blyleven vs Skip Lockwood | Second | 6½ out |
| Thursday, May 27 |
| » Lost to Brewers (17-23), 5-3 | County Stadium (2-1) | 23-22 | |
| » Starters: Jim Kaat vs Marty Pattin | Second | 7 out |
| Friday, May 28 |
| » Defeated Orioles (24-18), 7-6 | Metropolitan Stadium (12-9) | 24-22 | |
| » Starters: Dave McNally vs Jim Perry | Second | 6 out |
| Saturday, May 29 |
| » Lost to Orioles (25-18), 11-8 | Metropolitan Stadium (12-10) | 24-23 | |
| » Starters: Pat Dobson vs Pete Hamm | Second | 7 out |
| Sunday, May 30 |
| » Lost to Orioles (26-18), 6-5 | Metropolitan Stadium (12-11) | 24-24 | Lost 2 |
| » Starters: Mike Cuellar vs Bert Blyleven | Second | 7½ out |
| Monday, May 31 |
| » Defeated Tigers (26-22), 6-2 | Metropolitan Stadium (13-11) | 25-24 | |
| » Starters: Mickey Lolich vs Jim Kaat | Third | 7 out |
| Tuesday, June 1 |
| » Defeated Tigers (26-23), 3-1 | Metropolitan Stadium (14-11) | 26-24 | Won 2 |
| » Starters: Les Cain vs Jim Perry | Third | 7 out |
| Wednesday, June 2 |
| » Lost to Tigers (27-23), 5-4 | Metropolitan Stadium (14-12) | 26-25 | |
| » Starters: Joe Coleman vs Pete Hamm | Third | 7½ out |
| Friday, June 4 |
| » Lost to Indians (22-27), 4-2 | Metropolitan Stadium (14-13) | 26-26 | Lost 2 |
| » Starters: Alan Foster vs Bert Blyleven | Third | 8½ out |
| Saturday, June 5 |
| » Lost to Indians (23-27), 10-2 | Metropolitan Stadium (14-14) | 26-27 | Lost 3 |
| » Starters: Ray Lamb vs Jim Kaat | Third | 9½ out |
| Sunday, June 6 |
| » Defeated Indians (23-28), 4-3 | Metropolitan Stadium (15-14) | 27-27 | |
| » Starters: Steve Dunning vs Jim Perry | Third | 9½ out |
| Tuesday, June 8 |
| » Lost to Orioles (32-19), 8-2 | Memorial Stadium (0-1) | 27-28 | |
| » Starters: Bert Blyleven vs Pat Dobson | Third | 9½ out |
| Wednesday, June 9 |
| » Lost to Orioles (33-19), 2-1 | Memorial Stadium (0-2) | 27-29 | Lost 2 |
| » Starters: Jim Kaat vs Mike Cuellar | Third | 10½ out |
| Thursday, June 10 |
| » Lost to Orioles (34-19), 12-0 | Memorial Stadium (0-3) | 27-30 | Lost 3 |
| » Starters: Jim Perry vs Jim Palmer | Third | 11 out |
| Friday, June 11 |
| » Lost to Tigers (32-25), 4-1 | Tiger Stadium (0-1) | 27-31 | Lost 4 |
| » Starters: Bert Blyleven vs Mike Kilkenny | Fourth | 11 out |
| Saturday, June 12 |
| » Defeated Tigers (32-26), 5-4 | Tiger Stadium (1-1) | 28-31 | |
| » Starters: Stan Williams vs Mickey Lolich | Third | 11 out |
| Sunday, June 13 |
| » Lost to Tigers (33-26), 9-5 | Tiger Stadium (1-2) | 28-32 | |
| » Starters: Jim Kaat vs Les Cain | Third | 11 out |
| Monday, June 14 |
| » Defeated Indians (28-30), 3-1 | Cleveland Stadium (1-0) | 29-32 | |
| » Starters: Jim Perry vs Alan Foster | Third | 10½ out |
| Tuesday, June 15 |
| » Defeated Indians (28-31), 5-3 | Cleveland Stadium (2-0) | 30-32 | Won 2 |
| » Starters: Bert Blyleven vs Ray Lamb | Third | 10½ out |
| Wednesday, June 16 |
| » Defeated Indians (28-32), 3-2 | Cleveland Stadium (3-0) | 31-32 | Won 3 |
| » Starters: Jim Kaat vs Steve Dunning | Third | 10½ out |
| Thursday, June 17 |
| » Defeated White Sox (22-36), 7-6 | Metropolitan Stadium (16-14) | 32-32 | Won 4 |
| » Starters: Tommy John vs Ray Corbin | Third | 10 out |
| Friday, June 18 |
| » Defeated White Sox (22-37), 4-3 | Metropolitan Stadium (17-14) | 33-32 | Won 5 |
| » Starters: Tom Bradley vs Jim Perry | Third | 10 out |
| Saturday, June 19 |
| » Defeated White Sox (22-38), 2-1 | Metropolitan Stadium (18-14) | 34-32 | Won 6 |
| » Starters: Wilbur Wood vs Bert Blyleven | Third | 10 out |
| Sunday, June 20 |
| » Lost to White Sox (23-38), 18-8 | Metropolitan Stadium (18-15) | 34-33 | |
| » Starters: Joe Horlen vs Jim Kaat | Third | 10½ out |
| » Major-league debuts: Stan Perzanowski (White Sox) |
| Monday, June 21 |
| » Lost to Athletics (45-22), 3-2 | Metropolitan Stadium (18-16) | 34-34 | Lost 2 |
| » Starters: Vida Blue vs Ray Corbin | Third | 11½ out |
| Tuesday, June 22 |
| » Defeated Athletics (45-23), 10-1 | Metropolitan Stadium (19-16) | 35-34 | |
| » Starters: Catfish Hunter vs Jim Perry | Third | 10½ out |
| Wednesday, June 23 |
| » Lost to Athletics (46-23), 8-3 | Metropolitan Stadium (19-17) | 35-35 | |
| » Starters: Blue Moon Odom vs Bert Blyleven | Third | 11½ out |
| Friday, June 25 |
| » Lost to Brewers (27-39), 3-1 | Metropolitan Stadium (19-18) | 35-36 | Lost 2 |
| » Starters: Skip Lockwood vs Ray Corbin | Third | 12½ out |
| Saturday, June 26 |
| » Lost to Brewers (28-39), 5-0 | Metropolitan Stadium (19-19) | 35-37 | Lost 3 |
| » Starters: Marty Pattin vs Jim Perry | Third | 13½ out |
| Sunday, June 27 |
| » Defeated Brewers (28-40), 2-1 | Metropolitan Stadium (20-19) | 36-37 | |
| » Starters: Marcelino Lopez vs Jim Kaat | Third | 13½ out |
| » Lost to Brewers (29-40), 8-5 | Metropolitan Stadium (20-20) | 36-38 | |
| » Starters: Bill Parsons vs Steve Luebber | Third | 13½ out |
| » Major-league debuts: Steve Luebber (Twins) |
| Monday, June 28 |
| » Lost to Athletics (50-24), 6-4 | Oakland-Alameda County Stadium (1-3) | 36-39 | Lost 2 |
| » Starters: Bert Blyleven vs Chuck Dobson | Third | 14½ out |
| Tuesday, June 29 |
| » Defeated Athletics (50-25), 5-3 | Oakland-Alameda County Stadium (2-3) | 37-39 | |
| » Starters: Ray Corbin vs Vida Blue | Third | 13½ out |
| Wednesday, June 30 |
| » Defeated Athletics (50-26), 10-4 | Oakland-Alameda County Stadium (3-3) | 38-39 | Won 2 |
| » Starters: Jim Perry vs Catfish Hunter | Third | 12½ out |
| Friday, July 2 |
| » Lost to Brewers (32-43), 5-0 | County Stadium (2-2) | 38-40 | |
| » Starters: Bert Blyleven vs Bill Parsons | Third | 12½ out |
| Saturday, July 3 |
| » Defeated Brewers (32-44), 7-1 | County Stadium (3-2) | 39-40 | |
| » Starters: Jim Kaat vs Marcelino Lopez | Third | 12½ out |
| Sunday, July 4 |
| » Lost to Brewers (33-44), 4-0 | County Stadium (3-3) | 39-41 | |
| » Starters: Steve Luebber vs Jim Slaton | Third | 13½ out |
| Monday, July 5 |
| » Lost to Brewers (34-44), 2-1 | County Stadium (3-4) | 39-42 | Lost 2 |
| » Starters: Jim Perry vs Skip Lockwood | Third | 13½ out |
| Tuesday, July 6 |
| » Lost to Angels (38-48), 7-5 | Metropolitan Stadium (20-21) | 39-43 | Lost 3 |
| » Starters: Andy Messersmith vs Bert Blyleven | Third | 14½ out |
| Wednesday, July 7 |
| » Lost to Angels (39-48), 3-1 | Metropolitan Stadium (20-22) | 39-44 | Lost 4 |
| » Starters: Rickey Clark vs Jim Kaat | Third | 14½ out |
| Thursday, July 8 |
| » Lost to Angels (40-48), 7-4 | Metropolitan Stadium (20-23) | 39-45 | Lost 5 |
| » Starters: Tom Murphy vs Steve Luebber | Third | 15½ out |
| Friday, July 9 |
| » Lost to Royals (43-39), 6-3 | Metropolitan Stadium (20-24) | 39-46 | Lost 6 |
| » Starters: Mike Hedlund vs Jim Perry | Third | 16½ out |
| Sunday, July 11 |
| » Defeated Royals (43-40), 6-5 | Metropolitan Stadium (21-24) | 40-46 | |
| » Starters: Bruce DalCanton vs Jim Kaat | Third | 15 out |
| » Defeated Royals (43-41), 7-1 | Metropolitan Stadium (22-24) | 41-46 | Won 2 |
| » Starters: Dick Drago vs Ray Corbin | Third | 15 out |
| Thursday, July 15 |
| » Lost to Red Sox (50-37), 3-0 | Fenway Park (1-4) | 41-47 | |
| » Starters: Jim Perry vs Luis Tiant | Third | 16 out |
| Future Twin James Baldwin is born in Southern Pines, NC. |
| Friday, July 16 |
| » Lost to Red Sox (51-37), 9-4 | Fenway Park (1-5) | 41-48 | Lost 2 |
| » Starters: Bert Blyleven vs Sonny Siebert | Third | 17 out |
| Saturday, July 17 |
| » Defeated Senators (35-54), 5-3 | Robert F. Kennedy Stadium (2-2) | 42-48 | |
| » Starters: Jim Kaat vs Jim Shellenback | Third | 16 out |
| Sunday, July 18 |
| » Lost to Senators (36-54), 3-2 | Robert F. Kennedy Stadium (2-3) | 42-49 | |
| » Starters: Steve Luebber vs Bill Gogolewski | Fourth | 16 out |
| Monday, July 19 |
| » Lost to Senators (37-54), 5-2 | Robert F. Kennedy Stadium (2-4) | 42-50 | Lost 2 |
| » Starters: Jim Perry vs Jackie Brown | Fourth | 16 out |
| Tuesday, July 20 |
| » Lost to Yankees (46-50), 6-5 | Yankee Stadium (2-2) | 42-51 | Lost 3 |
| » Starters: Bert Blyleven vs Stan Bahnsen | Fourth | 17 out |
| Wednesday, July 21 |
| » Defeated Yankees (46-51), 2-1 | Yankee Stadium (3-2) | 43-51 | |
| » Starters: Jim Kaat vs Steve Kline | Fourth | 17 out |
| Thursday, July 22 |
| » Lost to Yankees (47-51), 13-4 | Yankee Stadium (3-3) | 43-52 | |
| » Starters: Ray Corbin vs Fritz Peterson | Fourth | 17½ out |
| Friday, July 23 |
| » Lost to Red Sox (56-39), 8-6 | Metropolitan Stadium (22-25) | 43-53 | Lost 2 |
| » Starters: Ray Culp vs Steve Luebber | Fourth | 18½ out |
| Saturday, July 24 |
| » Lost to Red Sox (57-39), 6-3 | Metropolitan Stadium (22-26) | 43-54 | Lost 3 |
| » Starters: Gary Peters vs Jim Perry | Fourth | 19½ out |
| Sunday, July 25 |
| » Defeated Red Sox (57-40), 6-2 | Metropolitan Stadium (23-26) | 44-54 | |
| » Starters: Luis Tiant vs Bert Blyleven | Fifth | 19 out |
| Monday, July 26 |
| » Defeated Red Sox (57-41), 2-1 | Metropolitan Stadium (24-26) | 45-54 | Won 2 |
| » Starters: Sonny Siebert vs Jim Kaat | Fourth | 18½ out |
| Tuesday, July 27 |
| » Defeated Senators (40-59), 4-2 | Metropolitan Stadium (25-26) | 46-54 | Won 3 |
| » Starters: Jim Shellenback vs Steve Luebber | Fourth | 17 out |
| Future Twin Shane Bowers is born in Glendora, CA. |
| Wednesday, July 28 |
| » Lost to Senators (41-59), 7-1 | Metropolitan Stadium (25-27) | 46-55 | |
| » Starters: Bill Gogolewski vs Jim Perry | Fifth | 17 out |
| Friday, July 30 |
| » Lost to Yankees (52-54), 11-9 | Metropolitan Stadium (25-28) | 46-56 | Lost 2 |
| » Starters: Stan Bahnsen vs Jim Kaat | Fifth | 17 out |
| Saturday, July 31 |
| » Defeated Yankees (52-55), 5-4 | Metropolitan Stadium (26-28) | 47-56 | |
| » Starters: Steve Kline vs Bert Blyleven | Fifth | 17 out |
| Sunday, August 1 |
| » Defeated Yankees (52-56), 10-7 | Metropolitan Stadium (27-28) | 48-56 | Won 2 |
| » Starters: Mel Stottlemyre vs Steve Luebber | Fourth | 17½ out |
| Monday, August 2 |
| » Lost to White Sox (50-57), 7-5 | Comiskey Park I (2-2) | 48-57 | |
| » Starters: Jim Perry vs Tom Bradley | Fifth | 18½ out |
| » Major-league debuts: Bob Gebhard (Twins) |
| Tuesday, August 3 |
| » Defeated White Sox (50-58), 4-3 | Comiskey Park I (3-2) | 49-57 | |
| » Starters: Jim Kaat vs Joe Horlen | Fifth | 18½ out |
| Wednesday, August 4 |
| » Lost to Royals (53-52), 2-1 | Municipal Stadium (1-2) | 49-58 | |
| » Starters: Bert Blyleven vs Dick Drago | Fifth | 20 out |
| » Lost to Royals (54-52), 3-0 | Municipal Stadium (1-3) | 49-59 | Lost 2 |
| » Starters: Ray Corbin vs Al Fitzmorris | Fifth | 20 out |
| Thursday, August 5 |
| » Lost to Royals (55-52), 7-4 | Municipal Stadium (1-4) | 49-60 | Lost 3 |
| » Starters: Tom Hall vs Roger Nelson | Fifth | 21 out |
| Future Twin Carlos Pulido is born in Caracas, Venezuela. |
| Friday, August 6 |
| » Lost to Angels (54-60), 2-0 | Anaheim Stadium (2-3) | 49-61 | Lost 4 |
| » Starters: Jim Perry vs Andy Messersmith | Fifth | 21 out |
| Saturday, August 7 |
| » Defeated Angels (54-61), 7-1 | Anaheim Stadium (3-3) | 50-61 | |
| » Starters: Jim Kaat vs Rudy May | Fifth | 21 out |
| Sunday, August 8 |
| » Defeated Angels (54-62), 2-1 | Anaheim Stadium (4-3) | 51-61 | Won 2 |
| » Starters: Bert Blyleven vs Tom Murphy | Fifth | 19½ out |
| Tuesday, August 10 |
| » Lost to Orioles (68-42), 4-3 | Metropolitan Stadium (27-29) | 51-62 | |
| » Starters: Mike Cuellar vs Tom Hall | Fifth | 21 out |
| Wednesday, August 11 |
| » Lost to Orioles (69-42), 9-6 | Metropolitan Stadium (27-30) | 51-63 | Lost 2 |
| » Starters: Pat Dobson vs Jim Perry | Fifth | 22 out |
| Thursday, August 12 |
| » Lost to Orioles (70-42), 8-2 | Metropolitan Stadium (27-31) | 51-64 | Lost 3 |
| » Starters: Jim Palmer vs Jim Kaat | Fifth | 23 out |
| Friday, August 13 |
| » Defeated Tigers (64-53), 4-3 | Metropolitan Stadium (28-31) | 52-64 | |
| » Starters: Les Cain vs Bert Blyleven | Fifth | 23 out |
| Saturday, August 14 |
| » Defeated Tigers (64-54), 9-4 | Metropolitan Stadium (29-31) | 53-64 | Won 2 |
| » Starters: Joe Coleman vs Steve Luebber | Fifth | 23 out |
| Sunday, August 15 |
| » Lost to Tigers (65-54), 7-5 | Metropolitan Stadium (29-32) | 53-65 | |
| » Starters: Mike Kilkenny vs Jim Perry | Fifth | 24 out |
| Monday, August 16 |
| » Defeated Indians (48-73), 11-2 | Metropolitan Stadium (30-32) | 54-65 | |
| » Starters: Ray Lamb vs Jim Kaat | Fifth | 23½ out |
| Tuesday, August 17 |
| » Lost to Indians (49-73), 3-2 | Metropolitan Stadium (30-33) | 54-66 | |
| » Starters: Mike Paul vs Bert Blyleven | Fifth | 23½ out |
| Wednesday, August 18 |
| » Defeated Indians (49-74), 4-2 | Metropolitan Stadium (31-33) | 55-66 | |
| » Starters: Steve Dunning vs Steve Luebber | Fifth | 22½ out |
| Friday, August 20 |
| » Defeated Orioles (74-45), 8-5 | Memorial Stadium (1-3) | 56-66 | Won 2 |
| » Starters: Jim Perry vs Pat Dobson | Fifth | 21½ out |
| Saturday, August 21 |
| » Lost to Orioles (75-45), 4-1 | Memorial Stadium (1-4) | 56-67 | |
| » Starters: Jim Kaat vs Jim Palmer | Fifth | 22½ out |
| Sunday, August 22 |
| » Lost to Orioles (76-45), 6-3 | Memorial Stadium (1-5) | 56-68 | Lost 2 |
| » Starters: Bert Blyleven vs Dave McNally | Fifth | 24 out |
| Monday, August 23 |
| » Lost to Tigers (68-58), 4-2 | Tiger Stadium (1-3) | 56-69 | Lost 3 |
| » Starters: Steve Luebber vs Les Cain | Fifth | 25 out |
| Tuesday, August 24 |
| » Defeated Tigers (68-59), 3-1 | Tiger Stadium (2-3) | 57-69 | |
| » Starters: Jim Perry vs Joe Niekro | Fifth | 24 out |
| Wednesday, August 25 |
| » Lost to Tigers (69-59), 6-2 | Tiger Stadium (2-4) | 57-70 | |
| » Starters: Jim Kaat vs Mickey Lolich | Fifth | 24 out |
| Friday, August 27 |
| » Defeated Indians (51-79), 8-4 | Cleveland Stadium (4-0) | 58-70 | |
| » Starters: Bert Blyleven vs Steve Dunning | Fifth | 24 out |
| Saturday, August 28 |
| » Lost to Indians (52-79), 9-8 | Cleveland Stadium (4-1) | 58-71 | |
| » Starters: Steve Luebber vs Alan Foster | Fifth | 25 out |
| Sunday, August 29 |
| » Defeated Indians (52-80), 6-5 | Cleveland Stadium (5-1) | 59-71 | |
| » Starters: Jim Perry vs Sam McDowell | Fifth | 25½ out |
| Tuesday, August 31 |
| » Defeated White Sox (63-70), 4-3 | Metropolitan Stadium (32-33) | 60-71 | Won 2 |
| » Starters: Tom Bradley vs Jim Kaat | Fifth | 25½ out |
| Wednesday, September 1 |
| » Lost to White Sox (64-70), 2-0 | Metropolitan Stadium (32-34) | 60-72 | |
| » Starters: Wilbur Wood vs Bert Blyleven | Fifth | 26½ out |
| Friday, September 3 |
| » Defeated Athletics (88-48), 9-4 | Metropolitan Stadium (33-34) | 61-72 | |
| » Starters: Diego Segui vs Jim Perry | Fifth | 24½ out |
| » Defeated Athletics (88-49), 2-1 | Metropolitan Stadium (34-34) | 62-72 | Won 2 |
| » Starters: Vida Blue vs Ray Corbin | Fifth | 24½ out |
| » Major-league debuts: Eric Soderholm (Twins) Dwain Anderson (Athletics) |
| Saturday, September 4 |
| » Lost to Athletics (89-49), 5-4 | Metropolitan Stadium (34-35) | 62-73 | |
| » Starters: Catfish Hunter vs Jim Kaat | Fifth | 25½ out |
| Sunday, September 5 |
| » Defeated Athletics (89-50), 7-3 | Metropolitan Stadium (35-35) | 63-73 | |
| » Starters: Blue Moon Odom vs Bert Blyleven | Fourth | 24½ out |
| Monday, September 6 |
| » Lost to White Sox (66-73), 6-3 | Comiskey Park I (3-3) | 63-74 | |
| » Starters: Tom Hall vs Bart Johnson | Fourth | 24 out |
| » Defeated White Sox (66-74), 10-3 | Comiskey Park I (4-3) | 64-74 | |
| » Starters: Pete Hamm vs Rich Hinton | Fourth | 24 out |
| Tuesday, September 7 |
| » Lost to White Sox (67-74), 8-7 | Comiskey Park I (4-4) | 64-75 | |
| » Starters: Jim Perry vs Tommy John | Fifth | 24 out |
| Wednesday, September 8 |
| » Defeated White Sox (67-75), 3-1 | Comiskey Park I (5-4) | 65-75 | |
| » Starters: Jim Kaat vs Wilbur Wood | Fifth | 24 out |
| Friday, September 10 |
| » Lost to Athletics (91-52), 5-4 | Oakland-Alameda County Stadium (3-4) | 65-76 | |
| » Starters: Bert Blyleven vs Blue Moon Odom | Fifth | 25 out |
| Saturday, September 11 |
| » Lost to Athletics (92-52), 5-3 | Oakland-Alameda County Stadium (3-5) | 65-77 | Lost 2 |
| » Starters: Ray Corbin vs Chuck Dobson | Fifth | 26 out |
| Sunday, September 12 |
| » Defeated Athletics (92-53), 7-5 | Oakland-Alameda County Stadium (4-5) | 66-77 | |
| » Starters: Jim Perry vs Vida Blue | Fifth | 25 out |
| Monday, September 13 |
| » Lost to Angels (69-78), 3-2 | Anaheim Stadium (4-4) | 66-78 | |
| » Starters: Pete Hamm vs Rudy May | Fifth | 25½ out |
| » Defeated Angels (69-79), 1-0 | Anaheim Stadium (5-4) | 67-78 | |
| » Starters: Jim Kaat vs Tom Murphy | Fifth | 25½ out |
| Future Twin Brent Brede is born in Belleville, IL. |
| Wednesday, September 15 |
| » Defeated Brewers (64-84), 1-0 | County Stadium (4-4) | 68-78 | Won 2 |
| » Starters: Bert Blyleven vs Skip Lockwood | Fourth | 24½ out |
| Thursday, September 16 |
| » Defeated Brewers (64-85), 7-3 | County Stadium (5-4) | 69-78 | Won 3 |
| » Starters: Ray Corbin vs Lew Krausse | Fifth | 24 out |
| Friday, September 17 |
| » Lost to Royals (80-70), 2-1 | Metropolitan Stadium (35-36) | 69-79 | |
| » Starters: Mike Hedlund vs Jim Perry | Fifth | 25 out |
| Saturday, September 18 |
| » Lost to Royals (81-70), 4-2 | Metropolitan Stadium (35-37) | 69-80 | Lost 2 |
| » Starters: Al Fitzmorris vs Jim Kaat | Fifth | 26 out |
| Sunday, September 19 |
| » Defeated Royals (81-71), 6-3 | Metropolitan Stadium (36-37) | 70-80 | |
| » Starters: Paul Splittorff vs Bert Blyleven | Fifth | 26½ out |
| » Lost to Royals (82-71), 5-2 | Metropolitan Stadium (36-38) | 70-81 | |
| » Starters: Monty Montgomery vs Pete Hamm | Fifth | 26½ out |
| Monday, September 20 |
| » Lost to Brewers (65-88), 3-0 | Metropolitan Stadium (36-39) | 70-82 | Lost 2 |
| » Starters: Skip Lockwood vs Ray Corbin | Fifth | 27 out |
| Tuesday, September 21 |
| » Lost to Brewers (66-88), 4-2 | Metropolitan Stadium (36-40) | 70-83 | Lost 3 |
| » Starters: Lew Krausse vs Jim Perry | Fifth | 26½ out |
| Saturday, September 25 |
| » Defeated Royals (84-72), 7-2 | Municipal Stadium (2-4) | 71-83 | |
| » Starters: Bert Blyleven vs Al Fitzmorris | Fifth | 24½ out |
| » Defeated Royals (84-73), 7-0 | Municipal Stadium (3-4) | 72-83 | Won 2 |
| » Starters: Jim Kaat vs Paul Splittorff | Fifth | 24½ out |
| Sunday, September 26 |
| » Defeated Royals (84-74), 6-2 | Municipal Stadium (4-4) | 73-83 | Won 3 |
| » Starters: Jim Perry vs Dick Drago | Fourth | 25 out |
| » Lost to Royals (85-74), 5-3 | Municipal Stadium (4-5) | 73-84 | |
| » Starters: Steve Luebber vs Monty Montgomery | Fourth | 25 out |
| Tuesday, September 28 |
| » Lost to Angels (75-85), 6-2 | Metropolitan Stadium (36-41) | 73-85 | Lost 2 |
| » Starters: Andy Messersmith vs Tom Hall | Fifth | 26 out |
| Wednesday, September 29 |
| » Defeated Angels (75-86), 1-0 | Metropolitan Stadium (37-41) | 74-85 | |
| » Starters: Clyde Wright vs Bert Blyleven | Fifth | 26 out |
| Thursday, September 30 |
| » Lost to Angels (76-86), 3-2 | Metropolitan Stadium (37-42) | 74-86 | |
| » Starters: Rudy May vs Jim Kaat | Fifth | 26½ out |
| Tuesday, October 12 |
| Future Twin Tony Fiore is born in Oak Park, IL. |
| Thursday, October 14 |
| Future Twin Midre Cummings is born in St. Croix, V.I. |
| Wednesday, November 3 |
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