| Friday, January 1 |
| Former Tiger Harry Rice dies in Portland, OR at the age of 70. |
| Tuesday, January 19 |
| Future Tiger Phil Nevin is born in Fullerton, CA. |
| Thursday, January 28 |
| Future Tiger Kevin Tolar is born in Panama City, FL. |
| Wednesday, February 17 |
| Future Tiger Danny Patterson is born in San Gabriel, CA. |
| Friday, March 5 |
| Future Tiger Brian Hunter is born in Portland, OR. |
| Thursday, March 11 |
| Former Tiger Clyde Barfoot dies in Highland Park, CA at the age of 80. |
| Tuesday, April 6 |
| » Defeated Indians (0-1), 8-2 | Tiger Stadium (1-0) | 1-0 | |
| » Starters: Steve Hargan vs Mickey Lolich | First | -- |
| Friday, April 9 |
| » Lost to Orioles (2-0), 6-5 | Memorial Stadium (0-1) | 1-1 | |
| » Starters: Joe Niekro vs Mike Cuellar | Third | 1 out |
| » Major-league debuts: Jim Foor (Tigers) |
| Saturday, April 10 |
| » Lost to Orioles (3-0), 2-1 | Memorial Stadium (0-2) | 1-2 | Lost 2 |
| » Starters: Mickey Lolich vs Jim Palmer | Fourth | 2 out |
| Sunday, April 11 |
| » Defeated Orioles (3-1), 5-4 | Memorial Stadium (1-2) | 2-2 | |
| » Starters: Dean Chance vs Pat Dobson | Fourth | 2 out |
| » Lost to Orioles (4-1), 9-3 | Memorial Stadium (1-3) | 2-3 | |
| » Starters: Mike Kilkenny vs Dave McNally | Fourth | 2 out |
| Monday, April 12 |
| Former Tiger Ed Lafitte dies in Jenkintown, PA at the age of 86. |
| Tuesday, April 13 |
| » Lost to Yankees (3-3), 5-2 | Yankee Stadium (0-1) | 2-4 | Lost 2 |
| » Starters: Joe Niekro vs Stan Bahnsen | Fifth | 2½ out |
| Wednesday, April 14 |
| » Lost to Yankees (4-3), 8-4 | Yankee Stadium (0-2) | 2-5 | Lost 3 |
| » Starters: Mickey Lolich vs Fritz Peterson | Sixth | 3½ out |
| Thursday, April 15 |
| » Defeated Yankees (4-4), 3-2 | Yankee Stadium (1-2) | 3-5 | |
| » Starters: Dean Chance vs Mel Stottlemyre | Sixth | 3½ out |
| Friday, April 16 |
| » Lost to Red Sox (4-4), 5-3 | Tiger Stadium (1-1) | 3-6 | |
| » Starters: Gary Peters vs Joe Niekro | Fifth | 4½ out |
| Saturday, April 17 |
| » Defeated Red Sox (4-5), 10-9 | Tiger Stadium (2-1) | 4-6 | |
| » Starters: Ray Culp vs Mickey Lolich | Fifth | 3½ out |
| Sunday, April 18 |
| » Lost to Red Sox (5-5), 1-0 | Tiger Stadium (2-2) | 4-7 | |
| » Starters: Sonny Siebert vs Dean Chance | Sixth | 4½ out |
| Monday, April 19 |
| Future Tiger Sean Whiteside is born in Lakeland, FL. |
| Tuesday, April 20 |
| » Defeated Orioles (8-3), 7-6 | Tiger Stadium (3-2) | 5-7 | |
| » Starters: Jim Palmer vs Joe Niekro | Fifth | 3½ out |
| Wednesday, April 21 |
| » Defeated Orioles (8-4), 5-1 | Tiger Stadium (4-2) | 6-7 | Won 2 |
| » Starters: Pat Dobson vs Mickey Lolich | Fourth | 2½ out |
| Friday, April 23 |
| » Lost to Athletics (13-5), 9-2 | Oakland-Alameda County Stadium (0-1) | 6-8 | |
| » Starters: Dean Chance vs Diego Segui | Fourth | 3½ out |
| Saturday, April 24 |
| » Lost to Athletics (14-5), 5-4 | Oakland-Alameda County Stadium (0-2) | 6-9 | Lost 2 |
| » Starters: Joe Coleman vs Catfish Hunter | Fourth | 3½ out |
| Sunday, April 25 |
| » Defeated Athletics (14-6), 10-2 | Oakland-Alameda County Stadium (1-2) | 7-9 | |
| » Starters: Mickey Lolich vs Rollie Fingers | Fourth | 3½ out |
| Monday, April 26 |
| » Defeated Royals (9-10), 8-3 | Municipal Stadium (1-0) | 8-9 | Won 2 |
| » Starters: Joe Niekro vs Jim Rooker | Third | 2½ out |
| Tuesday, April 27 |
| » Lost to Royals (10-10), 8-1 | Municipal Stadium (1-1) | 8-10 | |
| » Starters: Dean Chance vs Bruce DalCanton | Fourth | 3½ out |
| Wednesday, April 28 |
| » Defeated Royals (10-11), 2-1 | Municipal Stadium (2-1) | 9-10 | |
| » Starters: Mickey Lolich vs Dick Drago | Third | 2½ out |
| Friday, April 30 |
| » Defeated Angels (12-11), 7-4 | Anaheim Stadium (1-0) | 10-10 | Won 2 |
| » Starters: Joe Coleman vs Rudy May | Fourth | 2½ out |
| Saturday, May 1 |
| » Lost to Angels (13-11), 9-1 | Anaheim Stadium (1-1) | 10-11 | |
| » Starters: Dean Chance vs Andy Messersmith | Fourth | 2½ out |
| Sunday, May 2 |
| » Lost to Angels (14-11), 4-3 | Anaheim Stadium (1-2) | 10-12 | Lost 2 |
| » Starters: Mickey Lolich vs Clyde Wright | Fifth | 4 out |
| Tuesday, May 4 |
| » Defeated Athletics (18-11), 6-5 | Tiger Stadium (5-2) | 11-12 | |
| » Starters: Rollie Fingers vs Joe Coleman | Fourth | 4 out |
| Future Tiger Brian Maxcy is born in Amory, MS. |
| Wednesday, May 5 |
| » Lost to Athletics (19-11), 5-0 | Tiger Stadium (5-3) | 11-13 | |
| » Starters: Vida Blue vs Dean Chance | Fourth | 4½ out |
| Friday, May 7 |
| » Defeated Royals (14-13), 3-1 | Tiger Stadium (6-3) | 12-13 | |
| » Starters: Mike Hedlund vs Mickey Lolich | Fourth | 5 out |
| Saturday, May 8 |
| » Defeated Royals (14-14), 2-1 | Tiger Stadium (7-3) | 13-13 | Won 2 |
| » Starters: Wally Bunker vs Joe Coleman | Third | 5 out |
| Sunday, May 9 |
| » Lost to Royals (15-14), 6-2 | Tiger Stadium (7-4) | 13-14 | |
| » Starters: Ken Wright vs Joe Niekro | Third | 5 out |
| Monday, May 10 |
| » Defeated Angels (16-16), 5-2 | Tiger Stadium (8-4) | 14-14 | |
| » Starters: Andy Messersmith vs Dean Chance | Third | 4½ out |
| Tuesday, May 11 |
| » Lost to Angels (17-16), 5-0 | Tiger Stadium (8-5) | 14-15 | |
| » Starters: Clyde Wright vs Mickey Lolich | Third | 5½ out |
| Wednesday, May 12 |
| » Defeated Angels (17-17), 8-1 | Tiger Stadium (9-5) | 15-15 | |
| » Starters: Rudy May vs Joe Coleman | Fourth | 4½ out |
| Former Tiger Heinie Manush dies in Sarasota, FL at the age of 70. |
| Friday, May 14 |
| » Lost to Senators (14-18), 3-2 | Robert F. Kennedy Stadium (0-1) | 15-16 | |
| » Starters: Bill Zepp vs Denny McLain | Fourth | 5½ out |
| Saturday, May 15 |
| » Lost to Senators (15-18), 4-3 | Robert F. Kennedy Stadium (0-2) | 15-17 | Lost 2 |
| » Starters: Mickey Lolich vs Jerry Janeski | Fourth | 5½ out |
| Former Tiger Goose Goslin dies in Bridgeton, NJ at the age of 71. |
| Sunday, May 16 |
| » Defeated Senators (15-19), 5-4 | Robert F. Kennedy Stadium (1-2) | 16-17 | |
| » Starters: Joe Coleman vs Casey Cox | Third | 5 out |
| Monday, May 17 |
| » Lost to Red Sox (21-11), 3-2 | Fenway Park (0-1) | 16-18 | |
| » Starters: Dean Chance vs Ray Culp | Fourth | 6 out |
| Tuesday, May 18 |
| » Lost to Red Sox (22-11), 5-3 | Fenway Park (0-2) | 16-19 | Lost 2 |
| » Starters: Bill Zepp vs Gary Peters | Fourth | 7 out |
| Wednesday, May 19 |
| » Defeated Indians (14-21), 12-1 | Cleveland Stadium (1-0) | 17-19 | |
| » Starters: Mickey Lolich vs Ray Lamb | Third | 7 out |
| Thursday, May 20 |
| » Defeated Indians (14-22), 5-3 | Cleveland Stadium (2-0) | 18-19 | Won 2 |
| » Starters: Joe Coleman vs Alan Foster | Third | 7 out |
| Friday, May 21 |
| » Defeated Senators (15-23), 1-0 | Tiger Stadium (10-5) | 19-19 | Won 3 |
| » Starters: Jerry Janeski vs Dean Chance | Third | 7 out |
| Saturday, May 22 |
| » Defeated Senators (15-24), 3-1 | Tiger Stadium (11-5) | 20-19 | Won 4 |
| » Starters: Dick Bosman vs Bill Zepp | Third | 6 out |
| Sunday, May 23 |
| » Defeated Senators (15-25), 5-0 | Tiger Stadium (12-5) | 21-19 | Won 5 |
| » Starters: Denny McLain vs Mickey Lolich | Third | 5 out |
| » Defeated Senators (15-26), 11-0 | Tiger Stadium (13-5) | 22-19 | Won 6 |
| » Starters: Mike Thompson vs Les Cain | Third | 5 out |
| Tuesday, May 25 |
| » Defeated Yankees (17-23), 7-4 | Tiger Stadium (14-5) | 23-19 | Won 7 |
| » Starters: Stan Bahnsen vs Joe Coleman | Third | 3½ out |
| Wednesday, May 26 |
| » Lost to Yankees (18-23), 2-1 | Tiger Stadium (14-6) | 23-20 | |
| » Starters: Mel Stottlemyre vs Mike Kilkenny | Third | 4½ out |
| Thursday, May 27 |
| » Defeated Yankees (18-24), 4-3 | Tiger Stadium (15-6) | 24-20 | |
| » Starters: Fritz Peterson vs Mickey Lolich | Third | 4½ out |
| Friday, May 28 |
| » Defeated Brewers (17-24), 6-3 | County Stadium (1-0) | 25-20 | Won 2 |
| » Starters: Les Cain vs Bill Parsons | Third | 4½ out |
| Saturday, May 29 |
| » Lost to Brewers (18-24), 9-2 | County Stadium (1-1) | 25-21 | |
| » Starters: Joe Coleman vs Lew Krausse | Third | 4½ out |
| Sunday, May 30 |
| » Defeated Brewers (18-25), 9-5 | County Stadium (2-1) | 26-21 | |
| » Starters: Dean Chance vs John Morris | Third | 4 out |
| Monday, May 31 |
| » Lost to Twins (25-24), 6-2 | Metropolitan Stadium (0-1) | 26-22 | |
| » Starters: Mickey Lolich vs Jim Kaat | Third | 3½ out |
| Tuesday, June 1 |
| » Lost to Twins (26-24), 3-1 | Metropolitan Stadium (0-2) | 26-23 | Lost 2 |
| » Starters: Les Cain vs Jim Perry | Third | 3½ out |
| Wednesday, June 2 |
| » Defeated Twins (26-25), 5-4 | Metropolitan Stadium (1-2) | 27-23 | |
| » Starters: Joe Coleman vs Pete Hamm | Third | 2½ out |
| Friday, June 4 |
| » Lost to White Sox (19-27), 3-2 | Comiskey Park I (0-1) | 27-24 | |
| » Starters: Mickey Lolich vs Wilbur Wood | Third | 4 out |
| Saturday, June 5 |
| » Defeated White Sox (19-28), 7-3 | Comiskey Park I (1-1) | 28-24 | |
| » Starters: Les Cain vs Tommy John | Third | 3½ out |
| Sunday, June 6 |
| » Lost to White Sox (20-28), 8-2 | Comiskey Park I (1-2) | 28-25 | |
| » Starters: Joe Coleman vs Tom Bradley | Third | 4½ out |
| Tuesday, June 8 |
| » Defeated Brewers (20-30), 8-3 | Tiger Stadium (16-6) | 29-25 | |
| » Starters: Bill Parsons vs Mickey Lolich | Third | 4½ out |
| Wednesday, June 9 |
| » Defeated Brewers (20-31), 3-0 | Tiger Stadium (17-6) | 30-25 | Won 2 |
| » Starters: Lew Krausse vs Les Cain | Third | 4½ out |
| Thursday, June 10 |
| » Defeated Brewers (20-32), 3-2 | Tiger Stadium (18-6) | 31-25 | Won 3 |
| » Starters: Skip Lockwood vs Joe Coleman | Third | 4½ out |
| Friday, June 11 |
| » Defeated Twins (27-31), 4-1 | Tiger Stadium (19-6) | 32-25 | Won 4 |
| » Starters: Bert Blyleven vs Mike Kilkenny | Third | 4½ out |
| Saturday, June 12 |
| » Lost to Twins (28-31), 5-4 | Tiger Stadium (19-7) | 32-26 | |
| » Starters: Stan Williams vs Mickey Lolich | Third | 4½ out |
| Sunday, June 13 |
| » Defeated Twins (28-32), 9-5 | Tiger Stadium (20-7) | 33-26 | |
| » Starters: Jim Kaat vs Les Cain | Second | 4½ out |
| Monday, June 14 |
| » Defeated White Sox (21-34), 4-3 | Tiger Stadium (21-7) | 34-26 | Won 2 |
| » Starters: Tom Bradley vs Joe Coleman | Second | 4 out |
| Tuesday, June 15 |
| » Lost to White Sox (22-34), 6-1 | Tiger Stadium (21-8) | 34-27 | |
| » Starters: Joe Horlen vs Mike Kilkenny | Second | 4 out |
| Wednesday, June 16 |
| » Defeated White Sox (22-35), 6-5 | Tiger Stadium (22-8) | 35-27 | |
| » Starters: Terry Forster vs Mickey Lolich | Second | 4 out |
| Future Tiger Chris Gomez is born in Los Angeles, CA. Future Tiger Fernando Hernandez is born in Santiago, D.R. |
| Thursday, June 17 |
| » Defeated Indians (28-33), 4-3 | Cleveland Stadium (3-0) | 36-27 | Won 2 |
| » Starters: Les Cain vs Sam McDowell | Second | 4 out |
| Friday, June 18 |
| » Lost to Indians (29-33), 7-0 | Cleveland Stadium (3-1) | 36-28 | |
| » Starters: Joe Coleman vs Rich Hand | Second | 5 out |
| Saturday, June 19 |
| » Defeated Indians (29-34), 5-3 | Cleveland Stadium (4-1) | 37-28 | |
| » Starters: Dean Chance vs Alan Foster | Second | 4 out |
| Sunday, June 20 |
| » Lost to Indians (30-34), 7-6 | Cleveland Stadium (4-2) | 37-29 | |
| » Starters: Mickey Lolich vs Steve Dunning | Second | 5 out |
| » Game at Cleveland Stadium interrupted in the 8th inning with the score of Indians 7, Tigers 6. Completed on September 28. |
| Tuesday, June 22 |
| » Defeated Yankees (30-37), 7-4 | Yankee Stadium (2-2) | 38-29 | |
| » Starters: Les Cain vs Mel Stottlemyre | Second | 5½ out |
| » Lost to Yankees (31-37), 2-1 | Yankee Stadium (2-3) | 38-30 | |
| » Starters: Joe Coleman vs Stan Bahnsen | Second | 5½ out |
| Wednesday, June 23 |
| » Lost to Yankees (32-37), 6-5 | Yankee Stadium (2-4) | 38-31 | Lost 2 |
| » Starters: Mike Kilkenny vs Fritz Peterson | Third | 6½ out |
| Thursday, June 24 |
| » Defeated Indians (31-37), 3-0 | Tiger Stadium (23-8) | 39-31 | |
| » Starters: Alan Foster vs Mickey Lolich | Second | 6½ out |
| Friday, June 25 |
| » Defeated Indians (31-38), 6-1 | Tiger Stadium (24-8) | 40-31 | Won 2 |
| » Starters: Steve Dunning vs Bill Gilbreth | Second | 6½ out |
| » Major-league debuts: Bill Gilbreth (Tigers) |
| Saturday, June 26 |
| » Defeated Indians (31-39), 1-0 | Tiger Stadium (25-8) | 41-31 | Won 3 |
| » Starters: Steve Hargan vs Joe Coleman | Second | 5 out |
| Sunday, June 27 |
| » Lost to Indians (32-39), 3-1 | Tiger Stadium (25-9) | 41-32 | |
| » Starters: Sam McDowell vs Mike Kilkenny | Third | 5 out |
| Monday, June 28 |
| » Defeated Orioles (45-27), 9-4 | Memorial Stadium (2-3) | 42-32 | |
| » Starters: Mickey Lolich vs Dave McNally | Third | 4 out |
| Future Tiger Greg Keagle is born in Corning, NY. |
| Tuesday, June 29 |
| » Lost to Orioles (46-27), 15-6 | Memorial Stadium (2-4) | 42-33 | |
| » Starters: Les Cain vs Pat Dobson | Third | 5 out |
| » Major-league debuts: Chuck Seelbach (Tigers) |
| Wednesday, June 30 |
| » Lost to Red Sox (43-31), 6-4 | Tiger Stadium (25-10) | 42-34 | Lost 2 |
| » Starters: Gary Peters vs Joe Coleman | Third | 5½ out |
| Thursday, July 1 |
| » Lost to Red Sox (44-31), 8-7 | Tiger Stadium (25-11) | 42-35 | Lost 3 |
| » Starters: Sonny Siebert vs Bill Gilbreth | Third | 5½ out |
| » Major-league debuts: Buddy Hunter (Red Sox) |
| Future Tiger Jamie Walker is born in McMinnville, TN. |
| Friday, July 2 |
| » Defeated Orioles (47-30), 3-1 | Tiger Stadium (26-11) | 43-35 | |
| » Starters: Dave McNally vs Mickey Lolich | Third | 4½ out |
| Saturday, July 3 |
| » Lost to Orioles (48-30), 8-1 | Tiger Stadium (26-12) | 43-36 | |
| » Starters: Pat Dobson vs Les Cain | Third | 5½ out |
| Sunday, July 4 |
| » Lost to Orioles (49-30), 3-2 | Tiger Stadium (26-13) | 43-37 | Lost 2 |
| » Starters: Mike Cuellar vs Joe Coleman | Third | 6½ out |
| Tuesday, July 6 |
| » Defeated Yankees (37-46), 12-7 | Tiger Stadium (27-13) | 44-37 | |
| » Starters: Stan Bahnsen vs Mickey Lolich | Third | 6 out |
| Wednesday, July 7 |
| » Lost to Yankees (38-46), 5-3 | Tiger Stadium (27-14) | 44-38 | |
| » Starters: Fritz Peterson vs Mike Kilkenny | Third | 7 out |
| Thursday, July 8 |
| » Defeated Yankees (38-47), 3-1 | Tiger Stadium (28-14) | 45-38 | |
| » Starters: Steve Kline vs Bill Gilbreth | Third | 7 out |
| Friday, July 9 |
| » Defeated Senators (33-51), 1-0 | Robert F. Kennedy Stadium (2-2) | 46-38 | Won 2 |
| » Starters: Joe Coleman vs Pete Broberg | Third | 7 out |
| Saturday, July 10 |
| » Defeated Senators (33-52), 4-2 | Robert F. Kennedy Stadium (3-2) | 47-38 | Won 3 |
| » Starters: Mickey Lolich vs Denny McLain | Third | 6½ out |
| Sunday, July 11 |
| » Lost to Senators (34-52), 4-3 | Robert F. Kennedy Stadium (3-3) | 47-39 | |
| » Starters: Dean Chance vs Bill Gogolewski | Third | 7½ out |
| Thursday, July 15 |
| » Lost to Athletics (57-31), 8-7 | Oakland-Alameda County Stadium (1-3) | 47-40 | Lost 2 |
| » Starters: Mickey Lolich vs Chuck Dobson | Third | 8½ out |
| Friday, July 16 |
| » Lost to Athletics (58-31), 4-0 | Oakland-Alameda County Stadium (1-4) | 47-41 | Lost 3 |
| » Starters: Les Cain vs Vida Blue | Third | 8½ out |
| Saturday, July 17 |
| » Defeated Athletics (58-32), 2-1 | Oakland-Alameda County Stadium (2-4) | 48-41 | |
| » Starters: Joe Coleman vs Catfish Hunter | Third | 7½ out |
| Sunday, July 18 |
| » Lost to Royals (46-42), 8-2 | Municipal Stadium (2-2) | 48-42 | |
| » Starters: Bill Gilbreth vs Paul Splittorff | Third | 9 out |
| » Lost to Royals (47-42), 4-3 | Municipal Stadium (2-3) | 48-43 | Lost 2 |
| » Starters: Joe Niekro vs Bill Butler | Third | 9 out |
| Monday, July 19 |
| » Defeated Royals (47-43), 5-2 | Municipal Stadium (3-3) | 49-43 | |
| » Starters: Mickey Lolich vs Jim Rooker | Third | 9 out |
| Tuesday, July 20 |
| » Lost to Angels (46-52), 2-0 | Anaheim Stadium (1-3) | 49-44 | |
| » Starters: Les Cain vs Andy Messersmith | Third | 9 out |
| Wednesday, July 21 |
| » Defeated Angels (46-53), 6-3 | Anaheim Stadium (2-3) | 50-44 | |
| » Starters: Joe Coleman vs Clyde Wright | Third | 8½ out |
| » Lost to Angels (47-53), 7-6 | Anaheim Stadium (2-4) | 50-45 | |
| » Starters: Dean Chance vs Tom Murphy | Third | 8½ out |
| Friday, July 23 |
| » Lost to Athletics (61-34), 9-7 | Tiger Stadium (28-15) | 50-46 | Lost 2 |
| » Starters: Catfish Hunter vs Mickey Lolich | Third | 10 out |
| Saturday, July 24 |
| » Lost to Athletics (62-34), 7-2 | Tiger Stadium (28-16) | 50-47 | Lost 3 |
| » Starters: Blue Moon Odom vs Les Cain | Third | 10½ out |
| Sunday, July 25 |
| » Defeated Athletics (62-35), 7-4 | Tiger Stadium (29-16) | 51-47 | |
| » Starters: Chuck Dobson vs Joe Coleman | Third | 9½ out |
| » Lost to Athletics (63-35), 6-1 | Tiger Stadium (29-17) | 51-48 | |
| » Starters: Vida Blue vs Bill Denehy | Third | 9½ out |
| Monday, July 26 |
| Former Tiger Chick Lathers dies in Petoskey, MI at the age of 83. |
| Tuesday, July 27 |
| » Defeated Royals (52-46), 5-4 | Tiger Stadium (30-17) | 52-48 | |
| » Starters: Mike Hedlund vs Mickey Lolich | Third | 10 out |
| Wednesday, July 28 |
| » Defeated Royals (52-47), 8-7 | Tiger Stadium (31-17) | 53-48 | Won 2 |
| » Starters: Paul Splittorff vs Les Cain | Third | 10 out |
| Thursday, July 29 |
| » Defeated Royals (52-48), 10-9 | Tiger Stadium (32-17) | 54-48 | Won 3 |
| » Starters: Bill Butler vs Joe Coleman | Third | 9½ out |
| Friday, July 30 |
| » Defeated Angels (51-56), 4-3 | Tiger Stadium (33-17) | 55-48 | Won 4 |
| » Starters: Andy Messersmith vs Joe Niekro | Third | 9½ out |
| Saturday, July 31 |
| » Lost to Angels (52-56), 3-2 | Tiger Stadium (33-18) | 55-49 | |
| » Starters: Clyde Wright vs Mickey Lolich | Third | 10½ out |
| Sunday, August 1 |
| » Defeated Angels (52-57), 4-3 | Tiger Stadium (34-18) | 56-49 | |
| » Starters: Rickey Clark vs Les Cain | Third | 10 out |
| Monday, August 2 |
| » Defeated Senators (43-62), 11-7 | Tiger Stadium (35-18) | 57-49 | Won 2 |
| » Starters: Pete Broberg vs Joe Coleman | Third | 9 out |
| Tuesday, August 3 |
| » Lost to Senators (44-62), 4-2 | Tiger Stadium (35-19) | 57-50 | |
| » Starters: Denny McLain vs Joe Niekro | Third | 9½ out |
| Wednesday, August 4 |
| » Defeated Senators (44-63), 2-1 | Tiger Stadium (36-19) | 58-50 | |
| » Starters: Dick Bosman vs Mickey Lolich | Third | 9½ out |
| Thursday, August 5 |
| » Lost to Red Sox (63-46), 5-4 | Fenway Park (0-3) | 58-51 | |
| » Starters: Les Cain vs Gary Peters | Third | 9½ out |
| Friday, August 6 |
| » Defeated Red Sox (63-47), 2-0 | Fenway Park (1-3) | 59-51 | |
| » Starters: Joe Coleman vs Ray Culp | Third | 8½ out |
| Saturday, August 7 |
| » Defeated Red Sox (63-48), 12-8 | Fenway Park (2-3) | 60-51 | Won 2 |
| » Starters: Joe Niekro vs Sonny Siebert | Third | 8½ out |
| Sunday, August 8 |
| » Defeated Red Sox (63-49), 8-2 | Fenway Park (3-3) | 61-51 | Won 3 |
| » Starters: Mickey Lolich vs Luis Tiant | Third | 7½ out |
| Monday, August 9 |
| » Lost to Red Sox (64-49), 12-11 | Fenway Park (3-4) | 61-52 | |
| » Starters: Les Cain vs Jim Lonborg | Third | 8 out |
| Tuesday, August 10 |
| » Defeated Brewers (48-65), 12-3 | County Stadium (3-1) | 62-52 | |
| » Starters: Joe Coleman vs Bill Parsons | Third | 8 out |
| Wednesday, August 11 |
| » Defeated Brewers (48-66), 2-1 | County Stadium (4-1) | 63-52 | Won 2 |
| » Starters: Joe Niekro vs Skip Lockwood | Third | 8 out |
| Thursday, August 12 |
| » Defeated Brewers (48-67), 4-3 | County Stadium (5-1) | 64-52 | Won 3 |
| » Starters: Mickey Lolich vs Marty Pattin | Second | 8 out |
| Friday, August 13 |
| » Lost to Twins (52-64), 4-3 | Metropolitan Stadium (1-3) | 64-53 | |
| » Starters: Les Cain vs Bert Blyleven | Second | 9 out |
| Saturday, August 14 |
| » Lost to Twins (53-64), 9-4 | Metropolitan Stadium (1-4) | 64-54 | Lost 2 |
| » Starters: Joe Coleman vs Steve Luebber | Second | 9 out |
| Sunday, August 15 |
| » Defeated Twins (53-65), 7-5 | Metropolitan Stadium (2-4) | 65-54 | |
| » Starters: Mike Kilkenny vs Jim Perry | Second | 8 out |
| Tuesday, August 17 |
| » Lost to White Sox (58-63), 6-5 | Comiskey Park I (1-3) | 65-55 | |
| » Starters: Mickey Lolich vs Tommy John | Second | 10 out |
| » Lost to White Sox (59-63), 4-1 | Comiskey Park I (1-4) | 65-56 | Lost 2 |
| » Starters: Les Cain vs Joe Horlen | Second | 10 out |
| Wednesday, August 18 |
| » Lost to White Sox (60-63), 4-2 | Comiskey Park I (1-5) | 65-57 | Lost 3 |
| » Starters: Joe Coleman vs Wilbur Wood | Third | 11 out |
| Friday, August 20 |
| » Defeated Brewers (51-71), 3-2 | Tiger Stadium (37-19) | 66-57 | |
| » Starters: Bill Parsons vs Joe Niekro | Third | 10 out |
| Saturday, August 21 |
| » Defeated Brewers (51-72), 7-2 | Tiger Stadium (38-19) | 67-57 | Won 2 |
| » Starters: Skip Lockwood vs Mickey Lolich | Second | 10 out |
| Sunday, August 22 |
| » Lost to Brewers (52-72), 2-1 | Tiger Stadium (38-20) | 67-58 | |
| » Starters: Marty Pattin vs Joe Coleman | Second | 11 out |
| Monday, August 23 |
| » Defeated Twins (56-69), 4-2 | Tiger Stadium (39-20) | 68-58 | |
| » Starters: Steve Luebber vs Les Cain | Second | 10½ out |
| Future Tiger Allen McDill is born in Greenville, MS. |
| Tuesday, August 24 |
| » Lost to Twins (57-69), 3-1 | Tiger Stadium (39-21) | 68-59 | |
| » Starters: Jim Perry vs Joe Niekro | Second | 11½ out |
| Wednesday, August 25 |
| » Defeated Twins (57-70), 6-2 | Tiger Stadium (40-21) | 69-59 | |
| » Starters: Jim Kaat vs Mickey Lolich | Second | 11½ out |
| Friday, August 27 |
| » Defeated White Sox (62-68), 4-2 | Tiger Stadium (41-21) | 70-59 | Won 2 |
| » Starters: Rich Hinton vs Joe Coleman | Second | 11½ out |
| Saturday, August 28 |
| » Defeated White Sox (62-69), 5-4 | Tiger Stadium (42-21) | 71-59 | Won 3 |
| » Starters: Tom Bradley vs Les Cain | Second | 11 out |
| Sunday, August 29 |
| » Lost to White Sox (63-69), 6-2 | Tiger Stadium (42-22) | 71-60 | |
| » Starters: Wilbur Wood vs Mickey Lolich | Second | 11½ out |
| Tuesday, August 31 |
| » Defeated Indians (52-81), 6-1 | Tiger Stadium (43-22) | 72-60 | |
| » Starters: Ed Farmer vs Joe Coleman | Second | 11 out |
| » Lost to Indians (53-81), 6-3 | Tiger Stadium (43-23) | 72-61 | |
| » Starters: Vince Colbert vs Joe Niekro | Second | 11 out |
| Wednesday, September 1 |
| » Defeated Indians (53-82), 4-3 | Tiger Stadium (44-23) | 73-61 | |
| » Starters: Mike Paul vs Les Cain | Second | 11 out |
| Thursday, September 2 |
| » Defeated Indians (53-83), 7-0 | Tiger Stadium (45-23) | 74-61 | Won 2 |
| » Starters: Steve Dunning vs Mickey Lolich | Second | 10 out |
| Friday, September 3 |
| » Defeated Yankees (67-70), 3-1 | Yankee Stadium (3-4) | 75-61 | Won 3 |
| » Starters: Mike Kilkenny vs Fritz Peterson | Second | 10 out |
| Saturday, September 4 |
| » Defeated Yankees (67-71), 9-1 | Yankee Stadium (4-4) | 76-61 | Won 4 |
| » Starters: Joe Coleman vs Al Closter | Second | 10 out |
| » Major-league debuts: Marvin Lane (Tigers) |
| Sunday, September 5 |
| » Lost to Yankees (68-71), 6-5 | Yankee Stadium (4-5) | 76-62 | |
| » Starters: Les Cain vs Mike Kekich | Second | 10 out |
| Monday, September 6 |
| » Defeated Senators (58-81), 3-0 | Robert F. Kennedy Stadium (4-3) | 77-62 | |
| » Starters: Mickey Lolich vs Bill Gogolewski | Second | 9½ out |
| Tuesday, September 7 |
| » Defeated Senators (58-82), 3-2 | Robert F. Kennedy Stadium (5-3) | 78-62 | Won 2 |
| » Starters: Joe Coleman vs Mike Thompson | Second | 9½ out |
| Wednesday, September 8 |
| » Defeated Senators (58-83), 5-3 | Robert F. Kennedy Stadium (6-3) | 79-62 | Won 3 |
| » Starters: Mike Kilkenny vs Pete Broberg | Second | 9 out |
| Thursday, September 9 |
| » Lost to Red Sox (75-69), 12-6 | Tiger Stadium (45-24) | 79-63 | |
| » Starters: Jim Lonborg vs Bill Gilbreth | Second | 10 out |
| Friday, September 10 |
| » Lost to Red Sox (76-69), 6-1 | Tiger Stadium (45-25) | 79-64 | Lost 2 |
| » Starters: Gary Peters vs Mickey Lolich | Second | 11 out |
| Saturday, September 11 |
| » Defeated Red Sox (76-70), 1-0 | Tiger Stadium (46-25) | 80-64 | |
| » Starters: Ray Culp vs Joe Coleman | Second | 10½ out |
| Sunday, September 12 |
| » Defeated Red Sox (76-71), 3-2 | Tiger Stadium (47-25) | 81-64 | Won 2 |
| » Starters: John Curtis vs Les Cain | Second | 10 out |
| Monday, September 13 |
| » Lost to Orioles (89-51), 9-1 | Memorial Stadium (2-5) | 81-65 | |
| » Starters: Mike Kilkenny vs Dave McNally | Second | 10 out |
| » Defeated Orioles (89-52), 10-5 | Memorial Stadium (3-5) | 82-65 | |
| » Starters: Joe Niekro vs Pat Dobson | Second | 10 out |
| Tuesday, September 14 |
| » Defeated Orioles (89-53), 6-1 | Memorial Stadium (4-5) | 83-65 | Won 2 |
| » Starters: Mickey Lolich vs Jim Palmer | Second | 9 out |
| Wednesday, September 15 |
| » Defeated Senators (58-87), 4-2 | Tiger Stadium (48-25) | 84-65 | Won 3 |
| » Starters: Denny McLain vs Joe Coleman | Second | 8 out |
| Thursday, September 16 |
| » Defeated Senators (58-88), 3-1 | Tiger Stadium (49-25) | 85-65 | Won 4 |
| » Starters: Dick Bosman vs Les Cain | Second | 8 out |
| Friday, September 17 |
| » Defeated Orioles (90-55), 9-4 | Tiger Stadium (50-25) | 86-65 | Won 5 |
| » Starters: Dave McNally vs Tom Timmermann | Second | 6 out |
| » Defeated Orioles (90-56), 5-3 | Tiger Stadium (51-25) | 87-65 | Won 6 |
| » Starters: Dave Leonhard vs Fred Scherman | Second | 6 out |
| Saturday, September 18 |
| » Defeated Orioles (90-57), 2-1 | Tiger Stadium (52-25) | 88-65 | Won 7 |
| » Starters: Jim Palmer vs Mickey Lolich | Second | 5 out |
| Sunday, September 19 |
| » Lost to Orioles (91-57), 8-1 | Tiger Stadium (52-26) | 88-66 | |
| » Starters: Mike Cuellar vs Joe Coleman | Second | 6 out |
| Monday, September 20 |
| » Major-league debuts: Rusty Torres (Yankees) |
| Tuesday, September 21 |
| » Lost to Red Sox (81-74), 3-2 | Fenway Park (3-5) | 88-67 | Lost 2 |
| » Starters: Tom Timmermann vs Jim Lonborg | Second | 7½ out |
| Wednesday, September 22 |
| » Lost to Red Sox (82-74), 3-2 | Fenway Park (3-6) | 88-68 | Lost 3 |
| » Starters: Mickey Lolich vs Mike Garman | Second | 8½ out |
| Friday, September 24 |
| » Defeated Yankees (79-78), 8-5 | Tiger Stadium (53-26) | 89-68 | |
| » Starters: Mel Stottlemyre vs Joe Coleman | Second | 9 out |
| Saturday, September 25 |
| » Defeated Yankees (79-79), 10-7 | Tiger Stadium (54-26) | 90-68 | Won 2 |
| » Starters: Mike Kekich vs Les Cain | Second | 9 out |
| Sunday, September 26 |
| » Lost to Yankees (80-79), 3-2 | Tiger Stadium (54-27) | 90-69 | |
| » Starters: Fritz Peterson vs Mickey Lolich | Second | 10 out |
| Tuesday, September 28 |
| » Defeated Indians (58-102), 4-2 | Cleveland Stadium (5-2) | 91-69 | |
| » Starters: Joe Coleman vs Steve Hargan | Second | 11 out |
| » Lost to Indians (59-102), 8-7 | Cleveland Stadium (5-3) | 91-70 | |
| » Starters: Bill Zepp vs Ed Farmer | Second | 11 out |
| Wednesday, September 29 |
| » Lost to Indians (60-102), 2-1 | Cleveland Stadium (5-4) | 91-71 | Lost 2 |
| » Starters: Mickey Lolich vs Vince Colbert | Second | 12 out |
| Sunday, October 3 |
| Future Tiger Tim Hyers is born in Atlanta, GA. |
| Friday, November 5 |
| Former Tiger Sam Jones dies in Morgantown, WV at the age of 46. |
| Saturday, November 6 |
| Future Tiger Bubba Trammell is born in Knoxville, TN. |
| Wednesday, November 10 |
| Future Tiger Terry Pearson is born in Tuscaloosa, AL. |
| Monday, November 15 |
| Future Tiger Ryan Jackson is born in Orlando, FL. Future Tiger Todd Steverson is born in Los Angeles, CA. |
| Wednesday, November 17 |
| Future Tiger Billy McMillon is born in Otero, NM. |
| Thursday, December 9 |
| Future Tiger Todd Van Poppel is born in Hinsdale, IL. |
| Tuesday, December 28 |
| Future Tiger Melvin Nieves is born in San Juan, P.R. |
| Friday, December 31 |
| Future Tiger Brian Moehler is born in Rockingham, NC. |
Game information provided by Retrosheet (www.retrosheet.org) |