| Saturday, January 23 |
| Future Oriole Charlie Greene is born in Miami, FL. |
| Wednesday, February 3 |
| Future Oriole Scott Klingenbeck is born in Cincinnati, OH. |
| Thursday, March 4 |
| Future Oriole Nerio Rodriguez is born in San Pedro de Macoris, D.R. |
| Friday, March 5 |
| Future Oriole Jeffrey Hammonds is born in Plainfield, NJ. Future Oriole Jose Mercedes is born in El Seybo, D.R. |
| Saturday, March 20 |
| Future Oriole Manny Alexander is born in San Pedro de Macoris, D.R. |
| Friday, March 26 |
| Future Oriole Jesus Tavarez is born in Santo Domingo, D.R. |
| Tuesday, April 6 |
| » Major-league debuts: Steve Braun and Ray Corbin (Twins) |
| Wednesday, April 7 |
| » Defeated Senators (1-1), 3-2 | Memorial Stadium (1-0) | 1-0 | |
| » Starters: Casey Cox vs Dave McNally | First | -- |
| Friday, April 9 |
| » Defeated Tigers (1-1), 6-5 | Memorial Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Joe Niekro vs Mike Cuellar | First | -- |
| » Major-league debuts: Jim Foor (Tigers) |
| Saturday, April 10 |
| » Defeated Tigers (1-2), 2-1 | Memorial Stadium (3-0) | 3-0 | Won 3 |
| » Starters: Mickey Lolich vs Jim Palmer | First | -- |
| Future Oriole Al Reyes is born in San Cristobal, D.R. |
| Sunday, April 11 |
| » Lost to Tigers (2-2), 5-4 | Memorial Stadium (3-1) | 3-1 | |
| » Starters: Dean Chance vs Pat Dobson | First | -- |
| » Defeated Tigers (2-3), 9-3 | Memorial Stadium (4-1) | 4-1 | |
| » Starters: Mike Kilkenny vs Dave McNally | First | -- |
| Monday, April 12 |
| » Major-league debuts: Ron Theobald (Brewers) |
| Tuesday, April 13 |
| » Major-league debuts: Rick Auerbach and Bill Parsons (Brewers) |
| Wednesday, April 14 |
| » Defeated Indians (3-2), 3-0 | Cleveland Stadium (1-0) | 5-1 | Won 2 |
| » Starters: Mike Cuellar vs Sam McDowell | First | -- |
| Future Oriole Gregg Zaun is born in Glendale, CA. |
| Thursday, April 15 |
| » Defeated Indians (3-3), 6-4 | Cleveland Stadium (2-0) | 6-1 | Won 3 |
| » Starters: Jim Palmer vs Alan Foster | First | -- |
| Friday, April 16 |
| » Defeated Yankees (4-5), 6-1 | Memorial Stadium (5-1) | 7-1 | Won 4 |
| » Starters: Steve Kline vs Pat Dobson | First | -- |
| Saturday, April 17 |
| » Lost to Yankees (5-5), 5-3 | Memorial Stadium (5-2) | 7-2 | |
| » Starters: Mike Kekich vs Dave McNally | First | -- |
| Sunday, April 18 |
| » Defeated Yankees (5-6), 11-6 | Memorial Stadium (6-2) | 8-2 | |
| » Starters: Stan Bahnsen vs Mike Cuellar | First | -- |
| Tuesday, April 20 |
| » Lost to Tigers (5-7), 7-6 | Tiger Stadium (0-1) | 8-3 | |
| » Starters: Jim Palmer vs Joe Niekro | First | -- |
| Wednesday, April 21 |
| » Lost to Tigers (6-7), 5-1 | Tiger Stadium (0-2) | 8-4 | Lost 2 |
| » Starters: Pat Dobson vs Mickey Lolich | First | -- |
| Friday, April 23 |
| » Defeated Angels (8-8), 8-2 | Anaheim Stadium (1-0) | 9-4 | |
| » Starters: Dave McNally vs Clyde Wright | First | -- |
| Saturday, April 24 |
| » Lost to Angels (9-8), 7-4 | Anaheim Stadium (1-1) | 9-5 | |
| » Starters: Mike Cuellar vs Tom Murphy | First | -- |
| Sunday, April 25 |
| » Defeated Angels (9-9), 7-1 | Anaheim Stadium (2-1) | 10-5 | |
| » Starters: Jim Palmer vs Jim Maloney | First | -- |
| Monday, April 26 |
| » Lost to Athletics (15-6), 1-0 | Oakland-Alameda County Stadium (0-1) | 10-6 | |
| » Starters: Pat Dobson vs Vida Blue | First | -- |
| Tuesday, April 27 |
| » Defeated Athletics (15-7), 6-2 | Oakland-Alameda County Stadium (1-1) | 11-6 | |
| » Starters: Dave McNally vs Diego Segui | First | -- |
| Wednesday, April 28 |
| » Lost to Athletics (16-7), 5-4 | Oakland-Alameda County Stadium (1-2) | 11-7 | |
| » Starters: Mike Cuellar vs Catfish Hunter | First | -- |
| Thursday, April 29 |
| » Defeated Athletics (16-8), 3-2 | Oakland-Alameda County Stadium (2-2) | 12-7 | |
| » Starters: Jim Palmer vs Rollie Fingers | First | -- |
| Friday, April 30 |
| » Lost to Royals (11-11), 5-4 | Municipal Stadium (0-1) | 12-8 | |
| » Starters: Pat Dobson vs Mike Hedlund | Second | ½ out |
| Saturday, May 1 |
| » Lost to Royals (12-11), 5-2 | Municipal Stadium (0-2) | 12-9 | Lost 2 |
| » Starters: Dave McNally vs Wally Bunker | Second | ½ out |
| Sunday, May 2 |
| » Defeated Royals (12-12), 5-3 | Municipal Stadium (1-2) | 13-9 | |
| » Starters: Mike Cuellar vs Ken Wright | Second | 1 out |
| Future Oriole Brent Bowers is born in Oak Lawn, IL. |
| Tuesday, May 4 |
| » Defeated Angels (14-12), 4-1 | Memorial Stadium (7-2) | 14-9 | Won 2 |
| » Starters: Tom Murphy vs Jim Palmer | Second | 1 out |
| Future Oriole Joe Borowski is born in Bayonne, NJ. |
| Thursday, May 6 |
| » Defeated Angels (14-13), 3-1 | Memorial Stadium (8-2) | 15-9 | Won 3 |
| » Starters: Andy Messersmith vs Dave McNally | Second | ½ out |
| » Defeated Angels (14-14), 3-1 | Memorial Stadium (9-2) | 16-9 | Won 4 |
| » Starters: Jim Maloney vs Pat Dobson | Second | ½ out |
| Sunday, May 9 |
| » Lost to Athletics (20-11), 6-2 | Memorial Stadium (9-3) | 16-10 | |
| » Starters: Catfish Hunter vs Mike Cuellar | Second | 2 out |
| » Lost to Athletics (21-11), 2-1 | Memorial Stadium (9-4) | 16-11 | Lost 2 |
| » Starters: Vida Blue vs Jim Palmer | Second | 2 out |
| Monday, May 10 |
| » Lost to Royals (16-14), 4-1 | Memorial Stadium (9-5) | 16-12 | Lost 3 |
| » Starters: Bruce DalCanton vs Dave McNally | Second | 2½ out |
| Tuesday, May 11 |
| » Defeated Royals (16-15), 5-4 | Memorial Stadium (10-5) | 17-12 | |
| » Starters: Dick Drago vs Pat Dobson | Second | 2½ out |
| Future Oriole Kerry Ligtenberg is born in Rapid City, SD. |
| Wednesday, May 12 |
| » Defeated Royals (16-16), 6-0 | Memorial Stadium (11-5) | 18-12 | Won 2 |
| » Starters: Mike Hedlund vs Mike Cuellar | Second | 1½ out |
| Friday, May 14 |
| » Lost to Red Sox (20-10), 2-0 | Fenway Park (0-1) | 18-13 | |
| » Starters: Jim Palmer vs Sonny Siebert | Second | 2½ out |
| Saturday, May 15 |
| » Defeated Red Sox (20-11), 7-4 | Fenway Park (1-1) | 19-13 | |
| » Starters: Dave McNally vs Mike Nagy | Second | 1½ out |
| Monday, May 17 |
| » Lost to Yankees (16-16), 6-3 | Yankee Stadium (0-1) | 19-14 | |
| » Starters: Pat Dobson vs Mel Stottlemyre | Second | 2½ out |
| Tuesday, May 18 |
| » Defeated Yankees (16-17), 6-2 | Yankee Stadium (1-1) | 20-14 | |
| » Starters: Mike Cuellar vs Fritz Peterson | Second | 2½ out |
| Wednesday, May 19 |
| » Defeated Senators (15-22), 4-1 | Robert F. Kennedy Stadium (1-0) | 21-14 | Won 2 |
| » Starters: Jim Palmer vs Mike Thompson | Second | 2½ out |
| » Major-league debuts: Mike Thompson (Senators) |
| Friday, May 21 |
| » Lost to Red Sox (25-11), 8-4 | Memorial Stadium (11-6) | 21-15 | |
| » Starters: Jim Lonborg vs Pat Dobson | Second | 4 out |
| Saturday, May 22 |
| » Defeated Red Sox (25-12), 5-2 | Memorial Stadium (12-6) | 22-15 | |
| » Starters: Ray Culp vs Mike Cuellar | Second | 3 out |
| Sunday, May 23 |
| » Defeated Red Sox (25-13), 12-3 | Memorial Stadium (13-6) | 23-15 | Won 2 |
| » Starters: Gary Peters vs Jim Palmer | Second | 3 out |
| » Lost to Red Sox (26-13), 2-1 | Memorial Stadium (13-7) | 23-16 | |
| » Starters: Sonny Siebert vs Dave McNally | Second | 3 out |
| Wednesday, May 26 |
| » Defeated Indians (17-24), 3-2 | Memorial Stadium (14-7) | 24-16 | |
| » Starters: Rich Hand vs Mike Cuellar | Second | 2 out |
| Thursday, May 27 |
| » Lost to Indians (18-24), 10-5 | Memorial Stadium (14-8) | 24-17 | |
| » Starters: Steve Dunning vs Jim Palmer | Second | 3 out |
| Friday, May 28 |
| » Lost to Twins (24-22), 7-6 | Metropolitan Stadium (0-1) | 24-18 | Lost 2 |
| » Starters: Dave McNally vs Jim Perry | Second | 4 out |
| Saturday, May 29 |
| » Defeated Twins (24-23), 11-8 | Metropolitan Stadium (1-1) | 25-18 | |
| » Starters: Pat Dobson vs Pete Hamm | Second | 3 out |
| Sunday, May 30 |
| » Defeated Twins (24-24), 6-5 | Metropolitan Stadium (2-1) | 26-18 | Won 2 |
| » Starters: Mike Cuellar vs Bert Blyleven | Second | 2½ out |
| Monday, May 31 |
| » Lost to White Sox (18-25), 1-0 | Comiskey Park I (0-1) | 26-19 | |
| » Starters: Jim Palmer vs Tommy John | Second | 1½ out |
| » Defeated White Sox (18-26), 11-3 | Comiskey Park I (1-1) | 27-19 | |
| » Starters: Dave McNally vs Joe Horlen | Second | 1½ out |
| Wednesday, June 2 |
| » Defeated White Sox (18-27), 3-2 | Comiskey Park I (2-1) | 28-19 | Won 2 |
| » Starters: Pat Dobson vs Tom Bradley | First | -- |
| Thursday, June 3 |
| Future Oriole Aaron Ledesma is born in Union City, CA. |
| Friday, June 4 |
| » Defeated Brewers (20-27), 2-0 | County Stadium (1-0) | 29-19 | Won 3 |
| » Starters: Mike Cuellar vs Lew Krausse | Second | 1½ out |
| Saturday, June 5 |
| » Defeated Brewers (20-28), 12-4 | County Stadium (2-0) | 30-19 | Won 4 |
| » Starters: Jim Palmer vs Skip Lockwood | First | -- |
| Sunday, June 6 |
| » Defeated Brewers (20-29), 4-3 | County Stadium (3-0) | 31-19 | Won 5 |
| » Starters: Dave McNally vs Marty Pattin | First | -- |
| Tuesday, June 8 |
| » Defeated Twins (27-28), 8-2 | Memorial Stadium (15-8) | 32-19 | Won 6 |
| » Starters: Bert Blyleven vs Pat Dobson | First | -- |
| Wednesday, June 9 |
| » Defeated Twins (27-29), 2-1 | Memorial Stadium (16-8) | 33-19 | Won 7 |
| » Starters: Jim Kaat vs Mike Cuellar | First | -- |
| Thursday, June 10 |
| » Defeated Twins (27-30), 12-0 | Memorial Stadium (17-8) | 34-19 | Won 8 |
| » Starters: Jim Perry vs Jim Palmer | First | -- |
| Friday, June 11 |
| » Defeated White Sox (20-32), 8-5 | Memorial Stadium (18-8) | 35-19 | Won 9 |
| » Starters: Joe Horlen vs Dave McNally | First | -- |
| Saturday, June 12 |
| » Lost to White Sox (21-32), 7-3 | Memorial Stadium (18-9) | 35-20 | |
| » Starters: Wilbur Wood vs Pat Dobson | First | -- |
| Sunday, June 13 |
| » Defeated White Sox (21-33), 2-1 | Memorial Stadium (19-9) | 36-20 | |
| » Starters: Tommy John vs Mike Cuellar | First | -- |
| Tuesday, June 15 |
| » Lost to Brewers (22-34), 6-5 | Memorial Stadium (19-10) | 36-21 | |
| » Starters: Lew Krausse vs Jim Palmer | First | -- |
| Wednesday, June 16 |
| » Defeated Brewers (22-35), 8-3 | Memorial Stadium (20-10) | 37-21 | |
| » Starters: Marty Pattin vs Dave McNally | First | -- |
| Thursday, June 17 |
| » Defeated Yankees (29-34), 3-1 | Memorial Stadium (21-10) | 38-21 | Won 2 |
| » Starters: Mel Stottlemyre vs Pat Dobson | First | -- |
| Friday, June 18 |
| » Defeated Yankees (29-35), 6-4 | Memorial Stadium (22-10) | 39-21 | Won 3 |
| » Starters: Fritz Peterson vs Mike Cuellar | First | -- |
| Saturday, June 19 |
| » Lost to Yankees (30-35), 6-4 | Memorial Stadium (22-11) | 39-22 | |
| » Starters: Mike Kekich vs Jim Palmer | First | -- |
| Sunday, June 20 |
| » Defeated Yankees (30-36), 10-4 | Memorial Stadium (23-11) | 40-22 | |
| » Starters: Steve Kline vs Dave McNally | First | -- |
| Monday, June 21 |
| » Defeated Senators (23-40), 7-2 | Robert F. Kennedy Stadium (2-0) | 41-22 | Won 2 |
| » Starters: Pat Dobson vs Denny McLain | First | -- |
| Tuesday, June 22 |
| » Lost to Senators (24-40), 8-6 | Robert F. Kennedy Stadium (2-1) | 41-23 | |
| » Starters: Mike Cuellar vs Jerry Janeski | First | -- |
| » Defeated Senators (24-41), 2-0 | Robert F. Kennedy Stadium (3-1) | 42-23 | |
| » Starters: Grant Jackson vs Jim Shellenback | First | -- |
| Future Oriole Brian Sackinsky is born in Pittsburgh, PA. |
| Wednesday, June 23 |
| » Defeated Senators (24-42), 7-5 | Robert F. Kennedy Stadium (4-1) | 43-23 | Won 2 |
| » Starters: Jim Palmer vs Dick Bosman | First | -- |
| Thursday, June 24 |
| » Defeated Senators (24-43), 6-1 | Robert F. Kennedy Stadium (5-1) | 44-23 | Won 3 |
| » Starters: Dave McNally vs Jackie Brown | First | -- |
| Friday, June 25 |
| » Defeated Red Sox (37-31), 7-3 | Fenway Park (2-1) | 45-23 | Won 4 |
| » Starters: Pat Dobson vs Jim Lonborg | First | -- |
| Saturday, June 26 |
| » Lost to Red Sox (38-31), 3-2 | Fenway Park (2-2) | 45-24 | |
| » Starters: Mike Cuellar vs Gary Peters | First | -- |
| » Lost to Red Sox (39-31), 10-2 | Fenway Park (2-3) | 45-25 | Lost 2 |
| » Starters: Grant Jackson vs Sonny Siebert | First | -- |
| Sunday, June 27 |
| » Lost to Red Sox (40-31), 3-1 | Fenway Park (2-4) | 45-26 | Lost 3 |
| » Starters: Jim Palmer vs Ray Culp | First | -- |
| Monday, June 28 |
| » Lost to Tigers (42-32), 9-4 | Memorial Stadium (23-12) | 45-27 | Lost 4 |
| » Starters: Mickey Lolich vs Dave McNally | First | -- |
| Tuesday, June 29 |
| » Defeated Tigers (42-33), 15-6 | Memorial Stadium (24-12) | 46-27 | |
| » Starters: Les Cain vs Pat Dobson | First | -- |
| » Major-league debuts: Chuck Seelbach (Tigers) |
| Wednesday, June 30 |
| » Lost to Indians (35-40), 5-4 | Cleveland Stadium (2-1) | 46-28 | |
| » Starters: Mike Cuellar vs Steve Dunning | First | -- |
| » Defeated Indians (35-41), 4-3 | Cleveland Stadium (3-1) | 47-28 | |
| » Starters: Grant Jackson vs Steve Hargan | First | -- |
| Thursday, July 1 |
| » Lost to Indians (36-41), 3-2 | Cleveland Stadium (3-2) | 47-29 | |
| » Starters: Jim Palmer vs Sam McDowell | First | -- |
| Friday, July 2 |
| » Lost to Tigers (43-35), 3-1 | Tiger Stadium (0-3) | 47-30 | Lost 2 |
| » Starters: Dave McNally vs Mickey Lolich | First | -- |
| Saturday, July 3 |
| » Defeated Tigers (43-36), 8-1 | Tiger Stadium (1-3) | 48-30 | |
| » Starters: Pat Dobson vs Les Cain | First | -- |
| Sunday, July 4 |
| » Defeated Tigers (43-37), 3-2 | Tiger Stadium (2-3) | 49-30 | Won 2 |
| » Starters: Mike Cuellar vs Joe Coleman | First | -- |
| Tuesday, July 6 |
| » Defeated Senators (32-48), 6-2 | Memorial Stadium (25-12) | 50-30 | Won 3 |
| » Starters: Jim Shellenback vs Dave McNally | First | -- |
| » Lost to Senators (33-48), 3-2 | Memorial Stadium (25-13) | 50-31 | |
| » Starters: Bill Gogolewski vs Grant Jackson | First | -- |
| Wednesday, July 7 |
| » Defeated Senators (33-49), 4-0 | Memorial Stadium (26-13) | 51-31 | |
| » Starters: Dick Bosman vs Pat Dobson | First | -- |
| Thursday, July 8 |
| » Defeated Senators (33-50), 7-3 | Memorial Stadium (27-13) | 52-31 | Won 2 |
| » Starters: Jackie Brown vs Mike Cuellar | First | -- |
| Friday, July 9 |
| » Defeated Indians (37-49), 4-1 | Memorial Stadium (28-13) | 53-31 | Won 3 |
| » Starters: Steve Dunning vs Jim Palmer | First | -- |
| Saturday, July 10 |
| » Defeated Indians (37-50), 11-3 | Memorial Stadium (29-13) | 54-31 | Won 4 |
| » Starters: Sam McDowell vs Grant Jackson | First | -- |
| » Lost to Indians (38-50), 3-2 | Memorial Stadium (29-14) | 54-32 | |
| » Starters: Mike Paul vs Dave Boswell | First | -- |
| Sunday, July 11 |
| » Defeated Indians (38-51), 7-1 | Memorial Stadium (30-14) | 55-32 | |
| » Starters: Ed Farmer vs Pat Dobson | First | -- |
| Thursday, July 15 |
| » Defeated Angels (42-51), 4-3 | Anaheim Stadium (3-1) | 56-32 | Won 2 |
| » Starters: Pat Dobson vs Andy Messersmith | First | -- |
| Friday, July 16 |
| » Lost to Angels (43-51), 5-4 | Anaheim Stadium (3-2) | 56-33 | |
| » Starters: Mike Cuellar vs Clyde Wright | First | -- |
| Saturday, July 17 |
| » Lost to Angels (44-51), 10-3 | Anaheim Stadium (3-3) | 56-34 | Lost 2 |
| » Starters: Jim Palmer vs Tom Murphy | First | -- |
| Sunday, July 18 |
| » Defeated Athletics (58-33), 7-3 | Oakland-Alameda County Stadium (3-2) | 57-34 | |
| » Starters: Grant Jackson vs Blue Moon Odom | First | -- |
| Monday, July 19 |
| » Defeated Athletics (58-34), 4-2 | Oakland-Alameda County Stadium (4-2) | 58-34 | Won 2 |
| » Starters: Pat Dobson vs Diego Segui | First | -- |
| Tuesday, July 20 |
| » Lost to Royals (48-43), 7-1 | Municipal Stadium (1-3) | 58-35 | |
| » Starters: Mike Cuellar vs Dick Drago | First | -- |
| Future Oriole Charles Johnson is born in Fort Pierce, FL. |
| Wednesday, July 21 |
| » Lost to Royals (49-43), 7-2 | Municipal Stadium (1-4) | 58-36 | Lost 2 |
| » Starters: Jim Palmer vs Al Fitzmorris | First | -- |
| Thursday, July 22 |
| » Defeated Royals (49-44), 4-0 | Municipal Stadium (2-4) | 59-36 | |
| » Starters: Dave Leonhard vs Mike Hedlund | First | -- |
| Friday, July 23 |
| » Defeated Angels (47-54), 4-3 | Memorial Stadium (31-14) | 60-36 | Won 2 |
| » Starters: Rudy May vs Pat Dobson | First | -- |
| Sunday, July 25 |
| » Lost to Angels (48-54), 6-2 | Memorial Stadium (31-15) | 60-37 | |
| » Starters: Andy Messersmith vs Mike Cuellar | First | -- |
| » Lost to Angels (49-54), 9-6 | Memorial Stadium (31-16) | 60-38 | Lost 2 |
| » Starters: Rickey Clark vs Jim Palmer | First | -- |
| Tuesday, July 27 |
| » Defeated Athletics (63-36), 1-0 | Memorial Stadium (32-16) | 61-38 | |
| » Starters: Catfish Hunter vs Pat Dobson | First | -- |
| » Defeated Athletics (63-37), 6-4 | Memorial Stadium (33-16) | 62-38 | Won 2 |
| » Starters: Diego Segui vs Grant Jackson | First | -- |
| Wednesday, July 28 |
| » Defeated Athletics (63-38), 3-2 | Memorial Stadium (34-16) | 63-38 | Won 3 |
| » Starters: Blue Moon Odom vs Mike Cuellar | First | -- |
| Friday, July 30 |
| » Defeated Royals (52-49), 1-0 | Memorial Stadium (35-16) | 64-38 | Won 4 |
| » Starters: Dick Drago vs Jim Palmer | First | -- |
| Saturday, July 31 |
| » Defeated Royals (52-50), 4-0 | Memorial Stadium (36-16) | 65-38 | Won 5 |
| » Starters: Bruce DalCanton vs Pat Dobson | First | -- |
| Sunday, August 1 |
| Future Oriole Travis Driskill is born in Omaha, NE. |
| Monday, August 2 |
| » Lost to Red Sox (62-45), 7-4 | Memorial Stadium (36-17) | 65-39 | |
| » Starters: Luis Tiant vs Dave Leonhard | First | -- |
| Wednesday, August 4 |
| » Defeated Red Sox (62-46), 5-4 | Memorial Stadium (37-17) | 66-39 | |
| » Starters: Jim Lonborg vs Jim Palmer | First | -- |
| Thursday, August 5 |
| » Lost to Yankees (56-56), 5-0 | Yankee Stadium (1-2) | 66-40 | |
| » Starters: Mike Cuellar vs Mel Stottlemyre | First | -- |
| Friday, August 6 |
| » Lost to Yankees (57-56), 12-3 | Yankee Stadium (1-3) | 66-41 | Lost 2 |
| » Starters: Pat Dobson vs Fritz Peterson | First | -- |
| Saturday, August 7 |
| » Defeated Yankees (57-57), 3-1 | Yankee Stadium (2-3) | 67-41 | |
| » Starters: Jim Palmer vs Mike Kekich | First | -- |
| Sunday, August 8 |
| » Lost to Yankees (58-57), 2-1 | Yankee Stadium (2-4) | 67-42 | |
| » Starters: Grant Jackson vs Steve Kline | First | -- |
| Tuesday, August 10 |
| » Defeated Twins (51-62), 4-3 | Metropolitan Stadium (3-1) | 68-42 | |
| » Starters: Mike Cuellar vs Tom Hall | First | -- |
| Wednesday, August 11 |
| » Defeated Twins (51-63), 9-6 | Metropolitan Stadium (4-1) | 69-42 | Won 2 |
| » Starters: Pat Dobson vs Jim Perry | First | -- |
| Thursday, August 12 |
| » Defeated Twins (51-64), 8-2 | Metropolitan Stadium (5-1) | 70-42 | Won 3 |
| » Starters: Jim Palmer vs Jim Kaat | First | -- |
| Friday, August 13 |
| » Defeated White Sox (55-63), 12-1 | Comiskey Park I (3-1) | 71-42 | Won 4 |
| » Starters: Dave McNally vs Tommy John | First | -- |
| Saturday, August 14 |
| » Lost to White Sox (56-63), 2-0 | Comiskey Park I (3-2) | 71-43 | |
| » Starters: Mike Cuellar vs Tom Bradley | First | -- |
| Sunday, August 15 |
| » Lost to White Sox (57-63), 2-1 | Comiskey Park I (3-3) | 71-44 | Lost 2 |
| » Starters: Pat Dobson vs Wilbur Wood | First | -- |
| Monday, August 16 |
| » Defeated Brewers (51-68), 3-2 | County Stadium (4-0) | 72-44 | |
| » Starters: Jim Palmer vs Skip Lockwood | First | -- |
| Tuesday, August 17 |
| » Defeated Brewers (51-69), 3-2 | County Stadium (5-0) | 73-44 | Won 2 |
| » Starters: Dave McNally vs Marty Pattin | First | -- |
| Wednesday, August 18 |
| » Defeated Brewers (51-70), 6-4 | County Stadium (6-0) | 74-44 | Won 3 |
| » Starters: Mike Cuellar vs Jim Slaton | First | -- |
| Friday, August 20 |
| » Lost to Twins (56-66), 8-5 | Memorial Stadium (37-18) | 74-45 | |
| » Starters: Jim Perry vs Pat Dobson | First | -- |
| Saturday, August 21 |
| » Defeated Twins (56-67), 4-1 | Memorial Stadium (38-18) | 75-45 | |
| » Starters: Jim Kaat vs Jim Palmer | First | -- |
| Sunday, August 22 |
| » Defeated Twins (56-68), 6-3 | Memorial Stadium (39-18) | 76-45 | Won 2 |
| » Starters: Bert Blyleven vs Dave McNally | First | -- |
| Tuesday, August 24 |
| » Defeated White Sox (62-65), 1-0 | Memorial Stadium (40-18) | 77-45 | Won 3 |
| » Starters: Tom Bradley vs Mike Cuellar | First | -- |
| Wednesday, August 25 |
| » Defeated White Sox (62-66), 6-3 | Memorial Stadium (41-18) | 78-45 | Won 4 |
| » Starters: Wilbur Wood vs Pat Dobson | First | -- |
| Thursday, August 26 |
| » Defeated White Sox (62-67), 8-7 | Memorial Stadium (42-18) | 79-45 | Won 5 |
| » Starters: Joe Horlen vs Jim Palmer | First | -- |
| Saturday, August 28 |
| » Defeated Brewers (54-74), 9-4 | Memorial Stadium (43-18) | 80-45 | Won 6 |
| » Starters: Marty Pattin vs Dave McNally | First | -- |
| » Lost to Brewers (55-74), 3-0 | Memorial Stadium (43-19) | 80-46 | |
| » Starters: Lew Krausse vs Mike Cuellar | First | -- |
| Sunday, August 29 |
| » Defeated Brewers (55-75), 3-2 | Memorial Stadium (44-19) | 81-46 | |
| » Starters: Bill Parsons vs Pat Dobson | First | -- |
| » Lost to Brewers (56-75), 4-1 | Memorial Stadium (44-20) | 81-47 | |
| » Starters: Jim Slaton vs Dave Leonhard | First | -- |
| Tuesday, August 31 |
| » Lost to Red Sox (70-64), 4-3 | Fenway Park (2-5) | 81-48 | Lost 2 |
| » Starters: Jim Palmer vs Gary Peters | First | -- |
| Wednesday, September 1 |
| » Defeated Red Sox (70-65), 8-2 | Fenway Park (3-5) | 82-48 | |
| » Starters: Mike Cuellar vs Ray Culp | First | -- |
| Thursday, September 2 |
| » Lost to Red Sox (71-65), 3-0 | Fenway Park (3-6) | 82-49 | |
| » Starters: Pat Dobson vs Sonny Siebert | First | -- |
| Friday, September 3 |
| » Defeated Senators (57-79), 4-2 | Robert F. Kennedy Stadium (6-1) | 83-49 | |
| » Starters: Dave McNally vs Pete Broberg | First | -- |
| Saturday, September 4 |
| » Defeated Senators (57-80), 6-2 | Robert F. Kennedy Stadium (7-1) | 84-49 | Won 2 |
| » Starters: Jim Palmer vs Denny McLain | First | -- |
| Sunday, September 5 |
| » Lost to Senators (58-80), 5-3 | Robert F. Kennedy Stadium (7-2) | 84-50 | |
| » Starters: Mike Cuellar vs Dick Bosman | First | -- |
| Monday, September 6 |
| » Defeated Indians (54-86), 10-5 | Memorial Stadium (45-20) | 85-50 | |
| » Starters: Mike Paul vs Pat Dobson | First | -- |
| » Lost to Indians (55-86), 1-0 | Memorial Stadium (45-21) | 85-51 | |
| » Starters: Vince Colbert vs Dave Leonhard | First | -- |
| Tuesday, September 7 |
| » Defeated Indians (55-87), 3-1 | Memorial Stadium (46-21) | 86-51 | |
| » Starters: Sam McDowell vs Dave McNally | First | -- |
| Thursday, September 9 |
| » Defeated Senators (58-84), 4-2 | Memorial Stadium (47-21) | 87-51 | Won 2 |
| » Starters: Denny McLain vs Jim Palmer | First | -- |
| Friday, September 10 |
| » Defeated Senators (58-85), 7-1 | Memorial Stadium (48-21) | 88-51 | Won 3 |
| » Starters: Dick Bosman vs Mike Cuellar | First | -- |
| Monday, September 13 |
| » Defeated Tigers (81-65), 9-1 | Memorial Stadium (49-21) | 89-51 | Won 4 |
| » Starters: Mike Kilkenny vs Dave McNally | First | -- |
| » Lost to Tigers (82-65), 10-5 | Memorial Stadium (49-22) | 89-52 | |
| » Starters: Joe Niekro vs Pat Dobson | First | -- |
| Tuesday, September 14 |
| » Lost to Tigers (83-65), 6-1 | Memorial Stadium (49-23) | 89-53 | Lost 2 |
| » Starters: Mickey Lolich vs Jim Palmer | First | -- |
| Wednesday, September 15 |
| » Lost to Yankees (75-73), 4-2 | Memorial Stadium (49-24) | 89-54 | Lost 3 |
| » Starters: Steve Kline vs Mike Cuellar | First | -- |
| Thursday, September 16 |
| » Defeated Yankees (75-74), 6-2 | Memorial Stadium (50-24) | 90-54 | |
| » Starters: Mike Kekich vs Pat Dobson | First | -- |
| Friday, September 17 |
| » Lost to Tigers (86-65), 9-4 | Tiger Stadium (2-4) | 90-55 | |
| » Starters: Dave McNally vs Tom Timmermann | First | -- |
| » Lost to Tigers (87-65), 5-3 | Tiger Stadium (2-5) | 90-56 | Lost 2 |
| » Starters: Dave Leonhard vs Fred Scherman | First | -- |
| Saturday, September 18 |
| » Lost to Tigers (88-65), 2-1 | Tiger Stadium (2-6) | 90-57 | Lost 3 |
| » Starters: Jim Palmer vs Mickey Lolich | First | -- |
| Sunday, September 19 |
| » Defeated Tigers (88-66), 8-1 | Tiger Stadium (3-6) | 91-57 | |
| » Starters: Mike Cuellar vs Joe Coleman | First | -- |
| Monday, September 20 |
| » Defeated Yankees (79-75), 8-4 | Yankee Stadium (3-4) | 92-57 | Won 2 |
| » Starters: Pat Dobson vs Mike Kekich | First | -- |
| » Major-league debuts: Rusty Torres (Yankees) |
| Tuesday, September 21 |
| » Defeated Yankees (79-76), 5-0 | Yankee Stadium (4-4) | 93-57 | Won 3 |
| » Starters: Dave McNally vs Fritz Peterson | First | -- |
| Wednesday, September 22 |
| » Defeated Yankees (79-77), 10-1 | Yankee Stadium (5-4) | 94-57 | Won 4 |
| » Starters: Jim Palmer vs Stan Bahnsen | First | -- |
| Thursday, September 23 |
| Future Oriole Willie Greene is born in Milledgeville, GA. |
| Friday, September 24 |
| » Defeated Indians (58-98), 9-2 | Cleveland Stadium (4-2) | 95-57 | Won 5 |
| » Starters: Mike Cuellar vs Sam McDowell | First | -- |
| » Defeated Indians (58-99), 7-0 | Cleveland Stadium (5-2) | 96-57 | Won 6 |
| » Starters: Pat Dobson vs Mike Paul | First | -- |
| Saturday, September 25 |
| » Defeated Indians (58-100), 6-4 | Cleveland Stadium (6-2) | 97-57 | Won 7 |
| » Starters: Dave Leonhard vs Steve Dunning | First | -- |
| Sunday, September 26 |
| » Defeated Indians (58-101), 5-0 | Cleveland Stadium (7-2) | 98-57 | Won 8 |
| » Starters: Jim Palmer vs Alan Foster | First | -- |
| Tuesday, September 28 |
| » Defeated Red Sox (85-75), 10-2 | Memorial Stadium (51-24) | 99-57 | Won 9 |
| » Starters: Ray Culp vs Dave McNally | First | -- |
| » Defeated Red Sox (85-76), 5-4 | Memorial Stadium (52-24) | 100-57 | Won 10 |
| » Starters: Gary Peters vs Mike Cuellar | First | -- |
| Wednesday, September 29 |
| » Defeated Red Sox (85-77), 1-0 | Memorial Stadium (53-24) | 101-57 | Won 11 |
| » Starters: Mike Garman vs Grant Jackson | First | -- |
| Friday, November 5 |
| Former Oriole Sam Jones dies in Morgantown, WV at the age of 46. |
Game information provided by Retrosheet (www.retrosheet.org) |