| Tuesday, January 19 |
| Future Giant Jeff Juden is born in Salem, MA. |
| Sunday, January 24 |
| Future Giant Cory Bailey is born in Marion, IL. |
| Sunday, February 28 |
| Former Giant Lou Chiozza dies in Memphis, TN at the age of 61. |
| Wednesday, March 17 |
| Future Giant Bill Mueller is born in Maryland Heights, MO. |
| Sunday, April 4 |
| Former Giant Carl Mays dies in ElCajon, CA at the age of 80. |
| Tuesday, April 6 |
| » Defeated Padres (0-1), 4-0 | San Diego/Jack Murphy Stadium (1-0) | 1-0 | |
| » Starters: Juan Marichal vs Tom Phoebus | First | -- |
| Wednesday, April 7 |
| » Defeated Padres (0-2), 7-3 | San Diego/Jack Murphy Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Gaylord Perry vs Clay Kirby | First | -- |
| » Major-league debuts: Chris Speier (Giants) |
| Thursday, April 8 |
| » Lost to Padres (1-2), 7-6 | San Diego/Jack Murphy Stadium (2-1) | 2-1 | |
| » Starters: Steve Stone vs Steve Arlin | Third | ½ out |
| » Major-league debuts: Steve Stone (Giants) |
| Saturday, April 10 |
| » Defeated Cardinals (1-2), 6-4 | Busch Stadium II (1-0) | 3-1 | |
| » Starters: Frank Reberger vs Jerry Reuss | First | -- |
| Sunday, April 11 |
| » Lost to Cardinals (2-2), 4-2 | Busch Stadium II (1-1) | 3-2 | |
| » Starters: Rich Robertson vs Bob Gibson | Third | ½ out |
| » Defeated Cardinals (2-3), 7-2 | Busch Stadium II (2-1) | 4-2 | |
| » Starters: Juan Marichal vs Reggie Cleveland | Third | ½ out |
| Monday, April 12 |
| » Defeated Padres (3-4), 5-0 | Candlestick Park (1-0) | 5-2 | Won 2 |
| » Starters: Clay Kirby vs Gaylord Perry | First | -- |
| Wednesday, April 14 |
| » Defeated Astros (6-4), 2-1 | Candlestick Park (2-0) | 6-2 | Won 3 |
| » Starters: Tom Griffin vs Steve Stone | First | -- |
| Thursday, April 15 |
| » Defeated Astros (6-5), 4-3 | Candlestick Park (3-0) | 7-2 | Won 4 |
| » Starters: Larry Dierker vs Frank Reberger | First | -- |
| Friday, April 16 |
| » Defeated Cubs (4-6), 9-0 | Candlestick Park (4-0) | 8-2 | Won 5 |
| » Starters: Fergie Jenkins vs Juan Marichal | First | -- |
| Saturday, April 17 |
| » Defeated Cubs (4-7), 5-3 | Candlestick Park (5-0) | 9-2 | Won 6 |
| » Starters: Ken Holtzman vs Gaylord Perry | First | -- |
| Sunday, April 18 |
| » Defeated Cubs (4-8), 5-1 | Candlestick Park (6-0) | 10-2 | Won 7 |
| » Starters: Milt Pappas vs Steve Stone | First | -- |
| » Defeated Cubs (4-9), 8-1 | Candlestick Park (7-0) | 11-2 | Won 8 |
| » Starters: Bill Bonham vs Rich Robertson | First | -- |
| Monday, April 19 |
| » Defeated Cardinals (7-6), 4-2 | Candlestick Park (8-0) | 12-2 | Won 9 |
| » Starters: Jerry Reuss vs Frank Reberger | First | -- |
| Tuesday, April 20 |
| » Lost to Cardinals (8-6), 2-1 | Candlestick Park (8-1) | 12-3 | |
| » Starters: Reggie Cleveland vs Juan Marichal | First | -- |
| Wednesday, April 21 |
| » Lost to Cardinals (9-6), 5-3 | Candlestick Park (8-2) | 12-4 | Lost 2 |
| » Starters: Bob Gibson vs Gaylord Perry | First | -- |
| Friday, April 23 |
| » Defeated Pirates (9-7), 2-0 | Three Rivers Stadium (1-0) | 13-4 | |
| » Starters: Steve Stone vs Luke Walker | First | -- |
| Saturday, April 24 |
| » Defeated Pirates (9-8), 2-0 | Three Rivers Stadium (2-0) | 14-4 | Won 2 |
| » Starters: Ron Bryant vs Bob Johnson | First | -- |
| Sunday, April 25 |
| » Lost to Pirates (10-8), 6-2 | Three Rivers Stadium (2-1) | 14-5 | |
| » Starters: Juan Marichal vs Nelson Briles | First | -- |
| Tuesday, April 27 |
| » Defeated Braves (9-9), 6-5 | Atlanta-Fulton County Stadium (1-0) | 15-5 | |
| » Starters: Gaylord Perry vs Ron Reed | First | -- |
| Wednesday, April 28 |
| » Defeated Braves (9-10), 5-3 | Atlanta-Fulton County Stadium (2-0) | 16-5 | Won 2 |
| » Starters: Steve Stone vs Jim Nash | First | -- |
| Thursday, April 29 |
| » Defeated Braves (9-11), 5-2 | Atlanta-Fulton County Stadium (3-0) | 17-5 | Won 3 |
| » Starters: Ron Bryant vs Pat Jarvis | First | -- |
| Friday, April 30 |
| » Defeated Reds (8-12), 7-5 | Riverfront Stadium (1-0) | 18-5 | Won 4 |
| » Starters: Juan Marichal vs Jim Merritt | First | -- |
| Saturday, May 1 |
| » Lost to Reds (9-12), 3-2 | Riverfront Stadium (1-1) | 18-6 | |
| » Starters: Rich Robertson vs Don Gullett | First | -- |
| Sunday, May 2 |
| » Defeated Reds (9-13), 4-3 | Riverfront Stadium (2-1) | 19-6 | |
| » Starters: Gaylord Perry vs Gary Nolan | First | -- |
| Tuesday, May 4 |
| » Lost to Pirates (15-10), 10-2 | Candlestick Park (8-3) | 19-7 | |
| » Starters: Steve Blass vs Steve Stone | First | -- |
| Wednesday, May 5 |
| » Defeated Pirates (15-11), 2-1 | Candlestick Park (9-3) | 20-7 | |
| » Starters: Luke Walker vs Juan Marichal | First | -- |
| Friday, May 7 |
| » Defeated Braves (13-14), 4-3 | Candlestick Park (10-3) | 21-7 | Won 2 |
| » Starters: George Stone vs Gaylord Perry | First | -- |
| Saturday, May 8 |
| » Lost to Braves (14-14), 5-2 | Candlestick Park (10-4) | 21-8 | |
| » Starters: Ron Reed vs Ron Bryant | First | -- |
| Sunday, May 9 |
| » Defeated Braves (14-15), 5-2 | Candlestick Park (11-4) | 22-8 | |
| » Starters: Pat Jarvis vs Steve Stone | First | -- |
| » Lost to Braves (15-15), 6-5 | Candlestick Park (11-5) | 22-9 | |
| » Starters: Phil Niekro vs Rich Robertson | First | -- |
| Monday, May 10 |
| » Defeated Reds (11-18), 3-2 | Candlestick Park (12-5) | 23-9 | |
| » Starters: Wayne Simpson vs Juan Marichal | First | -- |
| Tuesday, May 11 |
| » Defeated Reds (11-19), 6-1 | Candlestick Park (13-5) | 24-9 | Won 2 |
| » Starters: Jim Merritt vs Gaylord Perry | First | -- |
| Wednesday, May 12 |
| » Defeated Reds (11-20), 7-2 | Candlestick Park (14-5) | 25-9 | Won 3 |
| » Starters: Don Gullett vs Ron Bryant | First | -- |
| Friday, May 14 |
| » Defeated Dodgers (17-18), 8-4 | Candlestick Park (15-5) | 26-9 | Won 4 |
| » Starters: Al Downing vs Steve Stone | First | -- |
| Saturday, May 15 |
| » Defeated Dodgers (17-19), 1-0 | Candlestick Park (16-5) | 27-9 | Won 5 |
| » Starters: Bill Singer vs Juan Marichal | First | -- |
| Sunday, May 16 |
| » Lost to Dodgers (18-19), 9-6 | Candlestick Park (16-6) | 27-10 | |
| » Starters: Claude Osteen vs Gaylord Perry | First | -- |
| Tuesday, May 18 |
| » Defeated Cubs (19-18), 7-3 | Wrigley Field (1-0) | 28-10 | |
| » Starters: Ron Bryant vs Milt Pappas | First | -- |
| Wednesday, May 19 |
| » Lost to Cubs (20-18), 9-5 | Wrigley Field (1-1) | 28-11 | |
| » Starters: Steve Stone vs Fergie Jenkins | First | -- |
| Thursday, May 20 |
| » Defeated Cubs (20-19), 8-7 | Wrigley Field (2-1) | 29-11 | |
| » Starters: Juan Marichal vs Ken Holtzman | First | -- |
| Friday, May 21 |
| » Lost to Astros (19-21), 4-1 | Astrodome (0-1) | 29-12 | |
| » Starters: Gaylord Perry vs Larry Dierker | First | -- |
| Saturday, May 22 |
| » Lost to Astros (20-21), 2-1 | Astrodome (0-2) | 29-13 | Lost 2 |
| » Starters: Rich Robertson vs Don Wilson | First | -- |
| Sunday, May 23 |
| » Defeated Astros (20-22), 7-4 | Astrodome (1-2) | 30-13 | |
| » Starters: Ron Bryant vs Tom Griffin | First | -- |
| Tuesday, May 25 |
| » Defeated Dodgers (21-23), 9-1 | Dodger Stadium (1-0) | 31-13 | Won 2 |
| » Starters: Juan Marichal vs Bill Singer | First | -- |
| Wednesday, May 26 |
| » Defeated Dodgers (21-24), 6-4 | Dodger Stadium (2-0) | 32-13 | Won 3 |
| » Starters: Gaylord Perry vs Claude Osteen | First | -- |
| Thursday, May 27 |
| » Lost to Dodgers (22-24), 5-1 | Dodger Stadium (2-1) | 32-14 | |
| » Starters: Ron Bryant vs Don Sutton | First | -- |
| Friday, May 28 |
| » Defeated Expos (18-20), 3-1 | Candlestick Park (17-6) | 33-14 | |
| » Starters: Steve Renko vs Steve Stone | First | -- |
| Saturday, May 29 |
| » Defeated Expos (18-21), 8-3 | Candlestick Park (18-6) | 34-14 | Won 2 |
| » Starters: Carl Morton vs Juan Marichal | First | -- |
| Sunday, May 30 |
| » Defeated Expos (18-22), 5-4 | Candlestick Park (19-6) | 35-14 | Won 3 |
| » Starters: Bill Stoneman vs Gaylord Perry | First | -- |
| » Defeated Expos (18-23), 8-7 | Candlestick Park (20-6) | 36-14 | Won 4 |
| » Starters: John Strohmayer vs Rich Robertson | First | -- |
| Monday, May 31 |
| » Defeated Mets (27-18), 2-1 | Candlestick Park (21-6) | 37-14 | Won 5 |
| » Starters: Jerry Koosman vs Ron Bryant | First | -- |
| Tuesday, June 1 |
| » Lost to Mets (28-18), 5-4 | Candlestick Park (21-7) | 37-15 | |
| » Starters: Gary Gentry vs Steve Stone | First | -- |
| Wednesday, June 2 |
| » Lost to Mets (29-18), 5-2 | Candlestick Park (21-8) | 37-16 | Lost 2 |
| » Starters: Jim McAndrew vs Juan Marichal | First | -- |
| Friday, June 4 |
| » Lost to Phillies (18-31), 5-3 | Candlestick Park (21-9) | 37-17 | Lost 3 |
| » Starters: Chris Short vs Gaylord Perry | First | -- |
| Saturday, June 5 |
| » Lost to Phillies (19-31), 5-3 | Candlestick Park (21-10) | 37-18 | Lost 4 |
| » Starters: Ken Reynolds vs Ron Bryant | First | -- |
| Sunday, June 6 |
| » Lost to Phillies (20-31), 1-0 | Candlestick Park (21-11) | 37-19 | Lost 5 |
| » Starters: Rick Wise vs Steve Stone | First | -- |
| » Defeated Phillies (20-32), 4-3 | Candlestick Park (22-11) | 38-19 | |
| » Starters: Barry Lersch vs Frank Reberger | First | -- |
| Tuesday, June 8 |
| » Lost to Expos (22-27), 10-3 | Parc Jarry (0-1) | 38-20 | |
| » Starters: Juan Marichal vs Bill Stoneman | First | -- |
| Wednesday, June 9 |
| » Lost to Expos (23-27), 4-0 | Parc Jarry (0-2) | 38-21 | Lost 2 |
| » Starters: Gaylord Perry vs Steve Renko | First | -- |
| Thursday, June 10 |
| » Lost to Expos (24-27), 3-1 | Parc Jarry (0-3) | 38-22 | Lost 3 |
| » Starters: Ron Bryant vs Carl Morton | First | -- |
| Friday, June 11 |
| » Defeated Mets (32-22), 3-2 | Shea Stadium (1-0) | 39-22 | |
| » Starters: Steve Stone vs Charlie Williams | First | -- |
| Saturday, June 12 |
| » Defeated Mets (32-23), 5-1 | Shea Stadium (2-0) | 40-22 | Won 2 |
| » Starters: Frank Reberger vs Ray Sadecki | First | -- |
| Sunday, June 13 |
| » Lost to Mets (33-23), 5-4 | Shea Stadium (2-1) | 40-23 | |
| » Starters: Juan Marichal vs Gary Gentry | First | -- |
| Monday, June 14 |
| » Lost to Phillies (24-35), 9-4 | Veteran's Stadium (0-1) | 40-24 | Lost 2 |
| » Starters: Gaylord Perry vs Rick Wise | First | -- |
| Tuesday, June 15 |
| » Defeated Phillies (24-36), 6-0 | Veteran's Stadium (1-1) | 41-24 | |
| » Starters: Ron Bryant vs Barry Lersch | First | -- |
| Wednesday, June 16 |
| » Lost to Phillies (25-36), 6-3 | Veteran's Stadium (1-2) | 41-25 | |
| » Starters: Steve Stone vs Jim Bunning | First | -- |
| Thursday, June 17 |
| » Major-league debuts: Burt Hooton (Cubs) |
| Friday, June 18 |
| » Defeated Padres (23-43), 7-3 | Candlestick Park (23-11) | 42-25 | |
| » Starters: Steve Arlin vs Juan Marichal | First | -- |
| » Defeated Padres (23-44), 10-9 | Candlestick Park (24-11) | 43-25 | Won 2 |
| » Starters: Tom Phoebus vs Frank Reberger | First | -- |
| Saturday, June 19 |
| » Defeated Padres (23-45), 7-4 | Candlestick Park (25-11) | 44-25 | Won 3 |
| » Starters: Clay Kirby vs Gaylord Perry | First | -- |
| Sunday, June 20 |
| » Defeated Padres (23-46), 6-2 | Candlestick Park (26-11) | 45-25 | Won 4 |
| » Starters: Fred Norman vs Ron Bryant | First | -- |
| » Defeated Padres (23-47), 2-0 | Candlestick Park (27-11) | 46-25 | Won 5 |
| » Starters: Dave Roberts vs Steve Stone | First | -- |
| Tuesday, June 22 |
| » Defeated Cubs (35-34), 2-0 | Candlestick Park (28-11) | 47-25 | Won 6 |
| » Starters: Fergie Jenkins vs John Cumberland | First | -- |
| Wednesday, June 23 |
| » Defeated Cubs (35-35), 5-2 | Candlestick Park (29-11) | 48-25 | Won 7 |
| » Starters: Milt Pappas vs Juan Marichal | First | -- |
| Friday, June 25 |
| » Lost to Astros (34-37), 5-4 | Astrodome (1-3) | 48-26 | |
| » Starters: Gaylord Perry vs Jack Billingham | First | -- |
| Saturday, June 26 |
| » Defeated Astros (34-38), 3-1 | Astrodome (2-3) | 49-26 | |
| » Starters: Ron Bryant vs Larry Dierker | First | -- |
| Sunday, June 27 |
| » Lost to Astros (35-38), 5-2 | Astrodome (2-4) | 49-27 | |
| » Starters: Steve Stone vs Ken Forsch | First | -- |
| Monday, June 28 |
| » Lost to Padres (27-51), 6-2 | San Diego/Jack Murphy Stadium (2-2) | 49-28 | Lost 2 |
| » Starters: Juan Marichal vs Clay Kirby | First | -- |
| Tuesday, June 29 |
| » Defeated Padres (27-52), 6-4 | San Diego/Jack Murphy Stadium (3-2) | 50-28 | |
| » Starters: John Cumberland vs Dave Roberts | First | -- |
| Wednesday, June 30 |
| » Lost to Padres (28-52), 2-1 | San Diego/Jack Murphy Stadium (3-3) | 50-29 | |
| » Starters: Gaylord Perry vs Steve Arlin | First | -- |
| Thursday, July 1 |
| » Defeated Cardinals (40-39), 8-7 | Candlestick Park (30-11) | 51-29 | |
| » Starters: Al Santorini vs Ron Bryant | First | -- |
| Friday, July 2 |
| » Lost to Cardinals (41-39), 7-2 | Candlestick Park (30-12) | 51-30 | |
| » Starters: Bob Gibson vs Steve Stone | First | -- |
| Saturday, July 3 |
| » Defeated Cardinals (41-40), 10-1 | Candlestick Park (31-12) | 52-30 | |
| » Starters: Steve Carlton vs John Cumberland | First | -- |
| Sunday, July 4 |
| » Lost to Dodgers (47-35), 14-4 | Candlestick Park (31-13) | 52-31 | |
| » Starters: Claude Osteen vs Juan Marichal | First | -- |
| Monday, July 5 |
| » Lost to Dodgers (48-35), 7-3 | Candlestick Park (31-14) | 52-32 | Lost 2 |
| » Starters: Don Sutton vs Gaylord Perry | First | -- |
| Tuesday, July 6 |
| » Lost to Astros (42-39), 5-2 | Candlestick Park (31-15) | 52-33 | Lost 3 |
| » Starters: Jack Billingham vs Ron Bryant | First | -- |
| Wednesday, July 7 |
| » Lost to Astros (43-39), 18-4 | Candlestick Park (31-16) | 52-34 | Lost 4 |
| » Starters: Larry Dierker vs Steve Stone | First | -- |
| Thursday, July 8 |
| » Defeated Astros (43-40), 4-2 | Candlestick Park (32-16) | 53-34 | |
| » Starters: Don Wilson vs John Cumberland | First | -- |
| Friday, July 9 |
| » Defeated Dodgers (48-40), 7-4 | Dodger Stadium (3-1) | 54-34 | Won 2 |
| » Starters: Juan Marichal vs Claude Osteen | First | -- |
| Saturday, July 10 |
| » Defeated Dodgers (48-41), 3-1 | Dodger Stadium (4-1) | 55-34 | Won 3 |
| » Starters: Gaylord Perry vs Don Sutton | First | -- |
| Sunday, July 11 |
| » Lost to Dodgers (49-41), 11-3 | Dodger Stadium (4-2) | 55-35 | |
| » Starters: Ron Bryant vs Al Downing | First | -- |
| Thursday, July 15 |
| » Lost to Reds (42-51), 2-1 | Riverfront Stadium (2-2) | 55-36 | Lost 2 |
| » Starters: John Cumberland vs Don Gullett | First | -- |
| Friday, July 16 |
| » Defeated Reds (42-52), 4-3 | Riverfront Stadium (3-2) | 56-36 | |
| » Starters: Gaylord Perry vs Gary Nolan | First | -- |
| Saturday, July 17 |
| » Lost to Reds (43-52), 3-2 | Riverfront Stadium (3-3) | 56-37 | |
| » Starters: Juan Marichal vs Jim McGlothlin | First | -- |
| Sunday, July 18 |
| » Defeated Braves (46-50), 5-4 | Atlanta-Fulton County Stadium (4-0) | 57-37 | |
| » Starters: Don Carrithers vs Jim Nash | First | -- |
| » Lost to Braves (47-50), 4-2 | Atlanta-Fulton County Stadium (4-1) | 57-38 | |
| » Starters: Steve Stone vs Tom Kelley | First | -- |
| Monday, July 19 |
| » Defeated Braves (47-51), 11-8 | Atlanta-Fulton County Stadium (5-1) | 58-38 | |
| » Starters: John Cumberland vs Steve Barber | First | -- |
| Tuesday, July 20 |
| » Lost to Pirates (63-32), 11-7 | Three Rivers Stadium (2-2) | 58-39 | |
| » Starters: Gaylord Perry vs Steve Blass | First | -- |
| Wednesday, July 21 |
| » Defeated Pirates (63-33), 8-4 | Three Rivers Stadium (3-2) | 59-39 | |
| » Starters: Ron Bryant vs Bob Johnson | First | -- |
| Thursday, July 22 |
| » Defeated Pirates (63-34), 8-7 | Three Rivers Stadium (4-2) | 60-39 | Won 2 |
| » Starters: Juan Marichal vs Dock Ellis | First | -- |
| Friday, July 23 |
| » Lost to Reds (47-54), 3-2 | Candlestick Park (32-17) | 60-40 | |
| » Starters: Ross Grimsley vs John Cumberland | First | -- |
| Saturday, July 24 |
| » Defeated Reds (47-55), 6-1 | Candlestick Park (33-17) | 61-40 | |
| » Starters: Wayne Simpson vs Don Carrithers | First | -- |
| Sunday, July 25 |
| » Defeated Reds (47-56), 7-3 | Candlestick Park (34-17) | 62-40 | Won 2 |
| » Starters: Gary Nolan vs Gaylord Perry | First | -- |
| » Lost to Reds (48-56), 5-2 | Candlestick Park (34-18) | 62-41 | |
| » Starters: Don Gullett vs Ron Bryant | First | -- |
| Former Giant Chief Meyers dies in San Bernardino, CA at the age of 91. |
| Tuesday, July 27 |
| » Lost to Braves (54-52), 4-3 | Candlestick Park (34-19) | 62-42 | Lost 2 |
| » Starters: Pat Jarvis vs Juan Marichal | First | -- |
| Wednesday, July 28 |
| » Defeated Braves (54-53), 2-1 | Candlestick Park (35-19) | 63-42 | |
| » Starters: George Stone vs John Cumberland | First | -- |
| Thursday, July 29 |
| » Lost to Braves (55-53), 4-2 | Candlestick Park (35-20) | 63-43 | |
| » Starters: Ron Reed vs Ron Bryant | First | -- |
| Friday, July 30 |
| » Defeated Pirates (67-38), 5-2 | Candlestick Park (36-20) | 64-43 | |
| » Starters: Bruce Kison vs Gaylord Perry | First | -- |
| Future Giant Calvin Murray is born in Dallas, TX. |
| Saturday, July 31 |
| » Defeated Pirates (67-39), 15-11 | Candlestick Park (37-20) | 65-43 | Won 2 |
| » Starters: Bob Johnson vs Don Carrithers | First | -- |
| » Major-league debuts: Jim Barr (Giants) |
| Sunday, August 1 |
| » Defeated Pirates (67-40), 11-7 | Candlestick Park (38-20) | 66-43 | Won 3 |
| » Starters: Bob Moose vs Juan Marichal | First | -- |
| » Defeated Pirates (67-41), 8-3 | Candlestick Park (39-20) | 67-43 | Won 4 |
| » Starters: Dock Ellis vs Frank Reberger | First | -- |
| Monday, August 2 |
| » Lost to Dodgers (58-51), 5-4 | Candlestick Park (39-21) | 67-44 | |
| » Starters: Claude Osteen vs John Cumberland | First | -- |
| Tuesday, August 3 |
| » Lost to Dodgers (59-51), 9-1 | Candlestick Park (39-22) | 67-45 | Lost 2 |
| » Starters: Doyle Alexander vs Ron Bryant | First | -- |
| Wednesday, August 4 |
| » Lost to Cardinals (61-50), 7-2 | Busch Stadium II (2-2) | 67-46 | Lost 3 |
| » Starters: Gaylord Perry vs Bob Gibson | First | -- |
| Thursday, August 5 |
| » Lost to Cardinals (62-50), 3-2 | Busch Stadium II (2-3) | 67-47 | Lost 4 |
| » Starters: Juan Marichal vs Reggie Cleveland | First | -- |
| Friday, August 6 |
| » Lost to Cardinals (63-50), 12-8 | Busch Stadium II (2-4) | 67-48 | Lost 5 |
| » Starters: John Cumberland vs Chris Zachary | First | -- |
| Saturday, August 7 |
| » Lost to Cubs (61-50), 6-5 | Wrigley Field (2-2) | 67-49 | Lost 6 |
| » Starters: Don Carrithers vs Fergie Jenkins | First | -- |
| Sunday, August 8 |
| » Defeated Cubs (61-51), 4-2 | Wrigley Field (3-2) | 68-49 | |
| » Starters: Gaylord Perry vs Bill Hands | First | -- |
| » Lost to Cubs (62-51), 8-0 | Wrigley Field (3-3) | 68-50 | |
| » Starters: Ron Bryant vs Milt Pappas | First | -- |
| Tuesday, August 10 |
| » Defeated Expos (45-70), 1-0 | Candlestick Park (40-22) | 69-50 | |
| » Starters: Bill Stoneman vs Juan Marichal | First | -- |
| Wednesday, August 11 |
| » Lost to Expos (46-70), 5-0 | Candlestick Park (40-23) | 69-51 | |
| » Starters: Steve Renko vs John Cumberland | First | -- |
| Friday, August 13 |
| » Defeated Mets (58-58), 7-3 | Candlestick Park (41-23) | 70-51 | |
| » Starters: Ray Sadecki vs Gaylord Perry | First | -- |
| Saturday, August 14 |
| » Defeated Mets (58-59), 6-5 | Candlestick Park (42-23) | 71-51 | Won 2 |
| » Starters: Jerry Koosman vs Don Carrithers | First | -- |
| Sunday, August 15 |
| » Defeated Mets (58-60), 6-1 | Candlestick Park (43-23) | 72-51 | Won 3 |
| » Starters: Jim McAndrew vs Juan Marichal | First | -- |
| Tuesday, August 17 |
| » Defeated Phillies (53-69), 5-1 | Candlestick Park (44-23) | 73-51 | Won 4 |
| » Starters: Ken Reynolds vs Gaylord Perry | First | -- |
| Wednesday, August 18 |
| » Defeated Phillies (53-70), 7-0 | Candlestick Park (45-23) | 74-51 | Won 5 |
| » Starters: Rick Wise vs John Cumberland | First | -- |
| Friday, August 20 |
| » Lost to Expos (51-71), 4-1 | Parc Jarry (0-4) | 74-52 | |
| » Starters: Juan Marichal vs Bill Stoneman | First | -- |
| Saturday, August 21 |
| » Lost to Expos (52-71), 4-3 | Parc Jarry (0-5) | 74-53 | Lost 2 |
| » Starters: Gaylord Perry vs Steve Renko | First | -- |
| Sunday, August 22 |
| » Lost to Expos (53-71), 6-3 | Parc Jarry (0-6) | 74-54 | Lost 3 |
| » Starters: John Cumberland vs Ernie McAnally | First | -- |
| Monday, August 23 |
| » Defeated Mets (62-63), 5-4 | Shea Stadium (3-1) | 75-54 | |
| » Starters: Don Carrithers vs Jim McAndrew | First | -- |
| Tuesday, August 24 |
| » Defeated Mets (62-64), 3-2 | Shea Stadium (4-1) | 76-54 | Won 2 |
| » Starters: Juan Marichal vs Ray Sadecki | First | -- |
| Wednesday, August 25 |
| » Lost to Mets (63-64), 5-1 | Shea Stadium (4-2) | 76-55 | |
| » Starters: Gaylord Perry vs Jerry Koosman | First | -- |
| Saturday, August 28 |
| » Defeated Phillies (56-74), 5-2 | Veteran's Stadium (2-2) | 77-55 | |
| » Starters: Don Carrithers vs Woodie Fryman | First | -- |
| » Lost to Phillies (57-74), 7-3 | Veteran's Stadium (2-3) | 77-56 | |
| » Starters: John Cumberland vs Rick Wise | First | -- |
| Sunday, August 29 |
| » Defeated Phillies (57-75), 8-3 | Veteran's Stadium (3-3) | 78-56 | |
| » Starters: Juan Marichal vs Ken Reynolds | First | -- |
| Tuesday, August 31 |
| » Defeated Braves (70-68), 9-0 | Candlestick Park (46-23) | 79-56 | Won 2 |
| » Starters: George Stone vs Gaylord Perry | First | -- |
| Wednesday, September 1 |
| » Defeated Braves (70-69), 4-0 | Candlestick Park (47-23) | 80-56 | Won 3 |
| » Starters: Ron Reed vs John Cumberland | First | -- |
| Thursday, September 2 |
| » Major-league debuts: Mike Anderson (Phillies) |
| Future Giant Rich Aurilia is born in Brooklyn, NY. |
| Friday, September 3 |
| » Defeated Astros (65-73), 16-6 | Candlestick Park (48-23) | 81-56 | Won 4 |
| » Starters: Wade Blasingame vs Juan Marichal | First | -- |
| Saturday, September 4 |
| » Defeated Astros (65-74), 1-0 | Candlestick Park (49-23) | 82-56 | Won 5 |
| » Starters: Ken Forsch vs Don Carrithers | First | -- |
| Sunday, September 5 |
| » Lost to Astros (66-74), 1-0 | Candlestick Park (49-24) | 82-57 | |
| » Starters: Jack Billingham vs Gaylord Perry | First | -- |
| » Lost to Astros (67-74), 5-3 | Candlestick Park (49-25) | 82-58 | Lost 2 |
| » Starters: J.R. Richard vs Jim Willoughby | First | -- |
| » Major-league debuts: Dave Rader and Jim Willoughby (Giants) J.R. Richard (Astros) |
| Monday, September 6 |
| » Lost to Dodgers (75-66), 5-2 | Dodger Stadium (4-3) | 82-59 | Lost 3 |
| » Starters: John Cumberland vs Don Sutton | First | -- |
| Tuesday, September 7 |
| » Lost to Dodgers (76-66), 9-3 | Dodger Stadium (4-4) | 82-60 | Lost 4 |
| » Starters: Ron Bryant vs Claude Osteen | First | -- |
| » Major-league debuts: Chris Arnold (Giants) |
| Wednesday, September 8 |
| » Lost to Dodgers (77-66), 3-0 | Dodger Stadium (4-5) | 82-61 | Lost 5 |
| » Starters: Juan Marichal vs Bill Singer | First | -- |
| Friday, September 10 |
| » Lost to Braves (73-72), 7-5 | Atlanta-Fulton County Stadium (5-2) | 82-62 | Lost 6 |
| » Starters: Gaylord Perry vs Phil Niekro | First | -- |
| Saturday, September 11 |
| » Lost to Braves (74-72), 5-4 | Atlanta-Fulton County Stadium (5-3) | 82-63 | Lost 7 |
| » Starters: Don Carrithers vs Tom Kelley | First | -- |
| Sunday, September 12 |
| » Defeated Braves (74-73), 6-1 | Atlanta-Fulton County Stadium (6-3) | 83-63 | |
| » Starters: John Cumberland vs George Stone | First | -- |
| Monday, September 13 |
| » Lost to Dodgers (81-66), 5-4 | Candlestick Park (49-26) | 83-64 | |
| » Starters: Bill Singer vs Juan Marichal | First | -- |
| Future Giant Armando Rios is born in Santurce, P.R. |
| Tuesday, September 14 |
| » Lost to Dodgers (82-66), 6-5 | Candlestick Park (49-27) | 83-65 | Lost 2 |
| » Starters: Al Downing vs Gaylord Perry | First | -- |
| Wednesday, September 15 |
| » Lost to Reds (73-78), 4-2 | Candlestick Park (49-28) | 83-66 | Lost 3 |
| » Starters: Jim McGlothlin vs Don Carrithers | First | -- |
| Thursday, September 16 |
| » Lost to Reds (74-78), 8-1 | Candlestick Park (49-29) | 83-67 | Lost 4 |
| » Starters: Ross Grimsley vs John Cumberland | First | -- |
| Friday, September 17 |
| » Defeated Padres (57-94), 7-5 | Candlestick Park (50-29) | 84-67 | |
| » Starters: Steve Arlin vs Juan Marichal | First | -- |
| Saturday, September 18 |
| » Lost to Padres (58-94), 2-1 | Candlestick Park (50-30) | 84-68 | |
| » Starters: Clay Kirby vs Gaylord Perry | First | -- |
| Sunday, September 19 |
| » Defeated Padres (58-95), 4-1 | Candlestick Park (51-30) | 85-68 | |
| » Starters: Dave Roberts vs Don Carrithers | First | -- |
| Tuesday, September 21 |
| » Lost to Astros (76-78), 3-1 | Astrodome (2-5) | 85-69 | |
| » Starters: John Cumberland vs Jack Billingham | First | -- |
| Wednesday, September 22 |
| » Defeated Astros (76-79), 3-1 | Astrodome (3-5) | 86-69 | |
| » Starters: Juan Marichal vs J.R. Richard | First | -- |
| Thursday, September 23 |
| » Defeated Astros (76-80), 2-1 | Astrodome (4-5) | 87-69 | Won 2 |
| » Starters: Gaylord Perry vs Don Wilson | First | -- |
| Friday, September 24 |
| » Lost to Reds (78-80), 6-5 | Riverfront Stadium (3-4) | 87-70 | |
| » Starters: Don Carrithers vs Ross Grimsley | First | -- |
| Saturday, September 25 |
| » Lost to Reds (79-80), 6-5 | Riverfront Stadium (3-5) | 87-71 | Lost 2 |
| » Starters: John Cumberland vs Don Gullett | First | -- |
| Sunday, September 26 |
| » Defeated Reds (79-81), 12-5 | Riverfront Stadium (4-5) | 88-71 | |
| » Starters: Juan Marichal vs Gary Nolan | First | -- |
| Tuesday, September 28 |
| » Defeated Padres (60-99), 7-1 | San Diego/Jack Murphy Stadium (4-3) | 89-71 | Won 2 |
| » Starters: Gaylord Perry vs Ed Acosta | First | -- |
| Future Giant Jamie Brewington is born in Greenville, NC. |
| Wednesday, September 29 |
| » Lost to Padres (61-99), 4-1 |
