| Sunday, January 17 |
| Future Cub Tyler Houston is born in Long Beach, CA. |
| Tuesday, February 16 |
| Future Cub Mike Hubbard is born in Lynchburg, VA. |
| Friday, February 19 |
| Future Cub Miguel Batista is born in Santo Domingo, D.R. |
| Saturday, March 20 |
| Future Cub Manny Alexander is born in San Pedro de Macoris, D.R. |
| Tuesday, April 6 |
| » Defeated Cardinals (0-1), 2-1 | Wrigley Field (1-0) | 1-0 | |
| » Starters: Bob Gibson vs Fergie Jenkins | First | -- |
| Wednesday, April 7 |
| » Lost to Cardinals (1-1), 14-3 | Wrigley Field (1-1) | 1-1 | |
| » Starters: Steve Carlton vs Bill Hands | Second | ½ out |
| » Major-league debuts: Bill Bonham and Hal Breeden (Cubs) |
| Thursday, April 8 |
| » Lost to Astros (3-1), 7-3 | Astrodome (0-1) | 1-2 | Lost 2 |
| » Starters: Ken Holtzman vs Jack Billingham | Third | 1½ out |
| Friday, April 9 |
| » Defeated Astros (3-2), 6-0 | Astrodome (1-1) | 2-2 | |
| » Starters: Milt Pappas vs Tom Griffin | Third | 1½ out |
| Saturday, April 10 |
| » Lost to Astros (4-2), 2-1 | Astrodome (1-2) | 2-3 | |
| » Starters: Fergie Jenkins vs Larry Dierker | Third | 1½ out |
| Sunday, April 11 |
| » Lost to Astros (5-2), 7-4 | Astrodome (1-3) | 2-4 | Lost 2 |
| » Starters: Bill Hands vs Don Wilson | Fifth | 2 out |
| Monday, April 12 |
| » Lost to Dodgers (3-4), 4-3 | Dodger Stadium (0-1) | 2-5 | Lost 3 |
| » Starters: Ken Holtzman vs Sandy Vance | Fifth | 2½ out |
| Tuesday, April 13 |
| » Defeated Dodgers (3-5), 3-2 | Dodger Stadium (1-1) | 3-5 | |
| » Starters: Milt Pappas vs Bill Singer | Fifth | 2½ out |
| Thursday, April 15 |
| » Defeated Padres (3-5), 4-3 | San Diego/Jack Murphy Stadium (1-0) | 4-5 | Won 2 |
| » Starters: Bill Hands vs Steve Arlin | Third | 1½ out |
| Friday, April 16 |
| » Lost to Giants (8-2), 9-0 | Candlestick Park (0-1) | 4-6 | |
| » Starters: Fergie Jenkins vs Juan Marichal | Fifth | 2 out |
| Former Cub Ron Northey dies in Pittsburgh, PA at the age of 51. |
| Saturday, April 17 |
| » Lost to Giants (9-2), 5-3 | Candlestick Park (0-2) | 4-7 | Lost 2 |
| » Starters: Ken Holtzman vs Gaylord Perry | Fifth | 2½ out |
| Sunday, April 18 |
| » Lost to Giants (10-2), 5-1 | Candlestick Park (0-3) | 4-8 | Lost 3 |
| » Starters: Milt Pappas vs Steve Stone | Fourth | 3½ out |
| » Lost to Giants (11-2), 8-1 | Candlestick Park (0-4) | 4-9 | Lost 4 |
| » Starters: Bill Bonham vs Rich Robertson | Fourth | 3½ out |
| Tuesday, April 20 |
| » Defeated Astros (8-7), 3-1 | Wrigley Field (2-1) | 5-9 | |
| » Starters: Tom Griffin vs Fergie Jenkins | Sixth | 3 out |
| » Major-league debuts: Rich Chiles (Astros) |
| Thursday, April 22 |
| » Lost to Astros (9-7), 6-1 | Wrigley Field (2-2) | 5-10 | |
| » Starters: Larry Dierker vs Bill Hands | Sixth | 4½ out |
| Friday, April 23 |
| » Lost to Mets (7-5), 7-6 | Wrigley Field (2-3) | 5-11 | Lost 2 |
| » Starters: Jerry Koosman vs Ken Holtzman | Sixth | 4 out |
| » Major-league debuts: Charlie Williams (Mets) |
| Saturday, April 24 |
| » Defeated Mets (7-6), 7-5 | Wrigley Field (3-3) | 6-11 | |
| » Starters: Gary Gentry vs Milt Pappas | Sixth | 4 out |
| Sunday, April 25 |
| » Defeated Mets (7-7), 9-3 | Wrigley Field (4-3) | 7-11 | Won 2 |
| » Starters: Jim McAndrew vs Fergie Jenkins | Fifth | 4 out |
| Wednesday, April 28 |
| » Defeated Expos (8-5), 3-2 | Wrigley Field (5-3) | 8-11 | Won 3 |
| » Starters: Carl Morton vs Bill Hands | Fifth | 3 out |
| Thursday, April 29 |
| » Lost to Expos (9-5), 7-6 | Wrigley Field (5-4) | 8-12 | |
| » Starters: Ernie McAnally vs Ken Holtzman | Fifth | 4 out |
| Friday, April 30 |
| » Lost to Phillies (7-12), 1-0 | Wrigley Field (5-5) | 8-13 | Lost 2 |
| » Starters: Chris Short vs Milt Pappas | Fifth | 5 out |
| Saturday, May 1 |
| » Defeated Phillies (7-13), 7-4 | Wrigley Field (6-5) | 9-13 | |
| » Starters: Rick Wise vs Fergie Jenkins | Fifth | 4 out |
| Sunday, May 2 |
| » Defeated Phillies (7-14), 7-1 | Wrigley Field (7-5) | 10-13 | Won 2 |
| » Starters: Jim Bunning vs Bill Hands | Fifth | 4 out |
| Monday, May 3 |
| » Lost to Mets (14-8), 3-2 | Shea Stadium (0-1) | 10-14 | |
| » Starters: Ken Holtzman vs Gary Gentry | Fifth | 5 out |
| Tuesday, May 4 |
| » Lost to Mets (15-8), 2-1 | Shea Stadium (0-2) | 10-15 | Lost 2 |
| » Starters: Milt Pappas vs Nolan Ryan | Fifth | 6 out |
| Future Cub Joe Borowski is born in Bayonne, NJ. |
| Wednesday, May 5 |
| » Defeated Mets (15-9), 5-4 | Shea Stadium (1-2) | 11-15 | |
| » Starters: Fergie Jenkins vs Jim McAndrew | Fifth | 5 out |
| Friday, May 7 |
| » Lost to Expos (11-8), 3-1 | Parc Jarry (0-1) | 11-16 | |
| » Starters: Bill Hands vs Carl Morton | Fifth | 6 out |
| Saturday, May 8 |
| » Defeated Expos (11-9), 3-0 | Parc Jarry (1-1) | 12-16 | |
| » Starters: Ken Holtzman vs Ernie McAnally | Fifth | 5½ out |
| Sunday, May 9 |
| » Lost to Expos (12-9), 7-3 | Parc Jarry (1-2) | 12-17 | |
| » Starters: Milt Pappas vs Bill Stoneman | Fifth | 6½ out |
| Monday, May 10 |
| » Defeated Phillies (9-18), 3-0 | Veteran's Stadium (1-0) | 13-17 | |
| » Starters: Fergie Jenkins vs Chris Short | Fifth | 6½ out |
| Tuesday, May 11 |
| » Defeated Phillies (9-19), 6-2 | Veteran's Stadium (2-0) | 14-17 | Won 2 |
| » Starters: Bill Hands vs Rick Wise | Fifth | 6½ out |
| Wednesday, May 12 |
| » Defeated Phillies (9-20), 9-4 | Veteran's Stadium (3-0) | 15-17 | Won 3 |
| » Starters: Ken Holtzman vs Jim Bunning | Fifth | 5½ out |
| Friday, May 14 |
| » Defeated Padres (10-22), 3-2 | Wrigley Field (8-5) | 16-17 | Won 4 |
| » Starters: Steve Arlin vs Milt Pappas | Fifth | 5½ out |
| Saturday, May 15 |
| » Defeated Padres (10-23), 6-4 | Wrigley Field (9-5) | 17-17 | Won 5 |
| » Starters: Tom Phoebus vs Fergie Jenkins | Fourth | 5½ out |
| Sunday, May 16 |
| » Defeated Padres (10-24), 9-8 | Wrigley Field (10-5) | 18-17 | Won 6 |
| » Starters: Danny Coombs vs Bill Hands | Fourth | 4 out |
| » Defeated Padres (10-25), 6-4 | Wrigley Field (11-5) | 19-17 | Won 7 |
| » Starters: Clay Kirby vs Ken Holtzman | Fourth | 4 out |
| » Major-league debuts: Ray Newman (Cubs) |
| Tuesday, May 18 |
| » Lost to Giants (28-10), 7-3 | Wrigley Field (11-6) | 19-18 | |
| » Starters: Ron Bryant vs Milt Pappas | Fourth | 3½ out |
| Future Cub Rich Garces is born in Maracay, Venezuela. |
| Wednesday, May 19 |
| » Defeated Giants (28-11), 9-5 | Wrigley Field (12-6) | 20-18 | |
| » Starters: Steve Stone vs Fergie Jenkins | Fourth | 3½ out |
| Thursday, May 20 |
| » Lost to Giants (29-11), 8-7 | Wrigley Field (12-7) | 20-19 | |
| » Starters: Juan Marichal vs Ken Holtzman | Fourth | 3½ out |
| Friday, May 21 |
| » Lost to Dodgers (20-21), 8-1 | Wrigley Field (12-8) | 20-20 | Lost 2 |
| » Starters: Claude Osteen vs Bill Hands | Fourth | 4½ out |
| Saturday, May 22 |
| » Defeated Dodgers (20-22), 5-2 | Wrigley Field (13-8) | 21-20 | |
| » Starters: Don Sutton vs Milt Pappas | Third | 3½ out |
| Sunday, May 23 |
| » Lost to Dodgers (21-22), 4-3 | Wrigley Field (13-9) | 21-21 | |
| » Starters: Al Downing vs Fergie Jenkins | Fourth | 4½ out |
| Tuesday, May 25 |
| » Lost to Cardinals (26-17), 4-2 | Busch Stadium II (0-1) | 21-22 | Lost 2 |
| » Starters: Bill Hands vs Steve Carlton | Fourth | 5½ out |
| Wednesday, May 26 |
| » Lost to Cardinals (27-17), 9-4 | Busch Stadium II (0-2) | 21-23 | Lost 3 |
| » Starters: Ken Holtzman vs Jerry Reuss | Fifth | 6 out |
| Thursday, May 27 |
| » Lost to Cardinals (28-17), 10-0 | Busch Stadium II (0-3) | 21-24 | Lost 4 |
| » Starters: Fergie Jenkins vs Chris Zachary | Fifth | 7 out |
| Former Cub Jack Doscher dies in Park Ridge, NJ at the age of 91. |
| Friday, May 28 |
| » Defeated Pirates (26-19), 4-2 | Three Rivers Stadium (1-0) | 22-24 | |
| » Starters: Milt Pappas vs Luke Walker | Fourth | 7 out |
| Saturday, May 29 |
| » Lost to Pirates (27-19), 9-4 | Three Rivers Stadium (1-1) | 22-25 | |
| » Starters: Bill Hands vs Bob Johnson | Fourth | 8 out |
| Sunday, May 30 |
| » Lost to Pirates (28-19), 10-0 | Three Rivers Stadium (1-2) | 22-26 | Lost 2 |
| » Starters: Ken Holtzman vs Bob Moose | Fourth | 9 out |
| Monday, May 31 |
| » Lost to Pirates (29-19), 6-0 | Three Rivers Stadium (1-3) | 22-27 | Lost 3 |
| » Starters: Fergie Jenkins vs Steve Blass | Fourth | 10 out |
| Wednesday, June 2 |
| » Defeated Reds (20-30), 6-3 | Riverfront Stadium (1-0) | 23-27 | |
| » Starters: Bill Hands vs Milt Wilcox | Fourth | 8 out |
| » Defeated Reds (20-31), 4-1 | Riverfront Stadium (2-0) | 24-27 | Won 2 |
| » Starters: Joe Decker vs Don Gullett | Fourth | 8 out |
| Thursday, June 3 |
| » Defeated Reds (20-32), 1-0 | Riverfront Stadium (3-0) | 25-27 | Won 3 |
| » Starters: Ken Holtzman vs Gary Nolan | Fourth | 8 out |
| Friday, June 4 |
| » Defeated Braves (24-30), 11-0 | Atlanta-Fulton County Stadium (1-0) | 26-27 | Won 4 |
| » Starters: Fergie Jenkins vs Phil Niekro | Fourth | 6½ out |
| Saturday, June 5 |
| » Lost to Braves (25-30), 6-4 | Atlanta-Fulton County Stadium (1-1) | 26-28 | |
| » Starters: Bill Bonham vs George Stone | Fourth | 8 out |
| Sunday, June 6 |
| » Defeated Braves (25-31), 6-3 | Atlanta-Fulton County Stadium (2-1) | 27-28 | |
| » Starters: Bill Hands vs Jim Nash | Fourth | 7 out |
| Monday, June 7 |
| » Lost to Pirates (34-21), 11-6 | Wrigley Field (13-10) | 27-29 | |
| » Starters: Nelson Briles vs Milt Pappas | Fourth | 8 out |
| Tuesday, June 8 |
| » Defeated Pirates (34-22), 1-0 | Wrigley Field (14-10) | 28-29 | |
| » Starters: Jim Nelson vs Ken Holtzman | Fourth | 7 out |
| Wednesday, June 9 |
| » Defeated Pirates (34-23), 3-1 | Wrigley Field (15-10) | 29-29 | Won 2 |
| » Starters: Bob Moose vs Fergie Jenkins | Fourth | 6 out |
| Friday, June 11 |
| » Lost to Reds (24-34), 4-3 | Wrigley Field (15-11) | 29-30 | |
| » Starters: Don Gullett vs Bill Hands | Fourth | 7 out |
| Saturday, June 12 |
| » Defeated Reds (24-35), 5-2 | Wrigley Field (16-11) | 30-30 | |
| » Starters: Jim McGlothlin vs Ken Holtzman | Fourth | 7 out |
| Sunday, June 13 |
| » Lost to Reds (25-35), 4-3 | Wrigley Field (16-12) | 30-31 | |
| » Starters: Gary Nolan vs Fergie Jenkins | Fourth | 8 out |
| Monday, June 14 |
| » Defeated Braves (29-35), 3-2 | Wrigley Field (17-12) | 31-31 | |
| » Starters: Phil Niekro vs Phil Regan | Fourth | 7 out |
| Tuesday, June 15 |
| » Defeated Braves (29-36), 3-1 | Wrigley Field (18-12) | 32-31 | Won 2 |
| » Starters: Tom Kelley vs Bill Hands | Fourth | 7 out |
| Wednesday, June 16 |
| » Lost to Braves (30-36), 6-5 | Wrigley Field (18-13) | 32-32 | |
| » Starters: Jim Nash vs Ken Holtzman | Fourth | 8 out |
| Thursday, June 17 |
| » Defeated Cardinals (36-30), 7-6 | Wrigley Field (19-13) | 33-32 | |
| » Starters: Steve Carlton vs Burt Hooton | Fourth | 7½ out |
| » Major-league debuts: Burt Hooton (Cubs) |
| Friday, June 18 |
| » Defeated Cardinals (36-31), 15-5 | Wrigley Field (20-13) | 34-32 | Won 2 |
| » Starters: Jerry Reuss vs Milt Pappas | Fourth | 7½ out |
| Saturday, June 19 |
| » Defeated Cardinals (36-32), 7-1 | Wrigley Field (21-13) | 35-32 | Won 3 |
| » Starters: Reggie Cleveland vs Bill Hands | Fourth | 6½ out |
| Sunday, June 20 |
| » Lost to Cardinals (37-32), 5-4 | Wrigley Field (21-14) | 35-33 | |
| » Starters: Al Santorini vs Ken Holtzman | Fourth | 8 out |
| Tuesday, June 22 |
| » Lost to Giants (47-25), 2-0 | Candlestick Park (0-5) | 35-34 | Lost 2 |
| » Starters: Fergie Jenkins vs John Cumberland | Fourth | 8½ out |
| Future Cub Brant Brown is born in Porterville, CA. |
| Wednesday, June 23 |
| » Lost to Giants (48-25), 5-2 | Candlestick Park (0-6) | 35-35 | Lost 3 |
| » Starters: Milt Pappas vs Juan Marichal | Fourth | 9½ out |
| Friday, June 25 |
| » Defeated Cardinals (39-35), 12-0 | Busch Stadium II (1-3) | 36-35 | |
| » Starters: Bill Hands vs Al Santorini | Fourth | 9½ out |
| Saturday, June 26 |
| » Defeated Cardinals (39-36), 5-1 | Busch Stadium II (2-3) | 37-35 | Won 2 |
| » Starters: Ken Holtzman vs Bob Gibson | Fourth | 9½ out |
| Sunday, June 27 |
| » Defeated Cardinals (39-37), 4-1 | Busch Stadium II (3-3) | 38-35 | Won 3 |
| » Starters: Fergie Jenkins vs Steve Carlton | Third | 9 out |
| Monday, June 28 |
| » Lost to Dodgers (43-33), 6-4 | Wrigley Field (21-15) | 38-36 | |
| » Starters: Al Downing vs Milt Pappas | Third | 10 out |
| Tuesday, June 29 |
| » Defeated Dodgers (43-34), 3-2 | Wrigley Field (22-15) | 39-36 | |
| » Starters: Bob O'Brien vs Bill Hands | Third | 9 out |
| Wednesday, June 30 |
| » Defeated Dodgers (43-35), 10-5 | Wrigley Field (23-15) | 40-36 | Won 2 |
| » Starters: Claude Osteen vs Ken Holtzman | Third | 8 out |
| Friday, July 2 |
| » Lost to Pirates (51-29), 5-1 | Wrigley Field (23-16) | 40-37 | |
| » Starters: Bob Moose vs Fergie Jenkins | Third | 9½ out |
| Saturday, July 3 |
| » Defeated Pirates (51-30), 3-1 | Wrigley Field (24-16) | 41-37 | |
| » Starters: Bob Johnson vs Milt Pappas | Third | 8½ out |
| Sunday, July 4 |
| » Defeated Pirates (51-31), 9-7 | Wrigley Field (25-16) | 42-37 | Won 2 |
| » Starters: Bruce Kison vs Bill Hands | Third | 7½ out |
| » Major-league debuts: Bruce Kison (Pirates) |
| Monday, July 5 |
| » Lost to Pirates (52-31), 6-2 | Wrigley Field (25-17) | 42-38 | |
| » Starters: Steve Blass vs Ken Holtzman | Third | 8½ out |
| Tuesday, July 6 |
| » Defeated Dodgers (48-36), 3-1 | Dodger Stadium (2-1) | 43-38 | |
| » Starters: Fergie Jenkins vs Bob O'Brien | Third | 8½ out |
| Wednesday, July 7 |
| » Defeated Dodgers (48-37), 6-5 | Dodger Stadium (3-1) | 44-38 | Won 2 |
| » Starters: Milt Pappas vs Al Downing | Third | 8 out |
| » Defeated Dodgers (48-38), 4-3 | Dodger Stadium (4-1) | 45-38 | Won 3 |
| » Starters: Juan Pizarro vs Doyle Alexander | Third | 8 out |
| Thursday, July 8 |
| » Defeated Dodgers (48-39), 4-2 | Dodger Stadium (5-1) | 46-38 | Won 4 |
| » Starters: Ken Holtzman vs Joe Moeller | Third | 8 out |
| Friday, July 9 |
| » Lost to Padres (31-56), 1-0 | San Diego/Jack Murphy Stadium (1-1) | 46-39 | |
| » Starters: Bill Hands vs Dave Roberts | Third | 9½ out |
| » Lost to Padres (32-56), 7-2 | San Diego/Jack Murphy Stadium (1-2) | 46-40 | Lost 2 |
| » Starters: Joe Decker vs Steve Arlin | Third | 9½ out |
| Saturday, July 10 |
| » Defeated Padres (32-57), 3-1 | San Diego/Jack Murphy Stadium (2-2) | 47-40 | |
| » Starters: Fergie Jenkins vs Fred Norman | Third | 9½ out |
| Sunday, July 11 |
| » Defeated Padres (32-58), 2-0 | San Diego/Jack Murphy Stadium (3-2) | 48-40 | Won 2 |
| » Starters: Milt Pappas vs Tom Phoebus | Second | 9½ out |
| » Lost to Padres (33-58), 7-5 | San Diego/Jack Murphy Stadium (3-3) | 48-41 | |
| » Starters: Juan Pizarro vs Clay Kirby | Second | 9½ out |
| Thursday, July 15 |
| » Defeated Phillies (39-51), 7-6 | Wrigley Field (26-17) | 49-41 | |
| » Starters: Rick Wise vs Ken Holtzman | Second | 9½ out |
| Friday, July 16 |
| » Defeated Phillies (39-52), 11-2 | Wrigley Field (27-17) | 50-41 | Won 2 |
| » Starters: Chris Short vs Fergie Jenkins | Second | 9½ out |
| Saturday, July 17 |
| » Lost to Phillies (40-52), 5-2 | Wrigley Field (27-18) | 50-42 | |
| » Starters: Woodie Fryman vs Bill Hands | Second | 10½ out |
| Sunday, July 18 |
| » Defeated Expos (36-57), 8-4 | Wrigley Field (28-18) | 51-42 | |
| » Starters: Dan McGinn vs Milt Pappas | Second | 11 out |
| Monday, July 19 |
| » Lost to Expos (37-57), 5-3 | Wrigley Field (28-19) | 51-43 | |
| » Starters: John Strohmayer vs Ken Holtzman | Second | 11 out |
| Tuesday, July 20 |
| » Defeated Mets (48-44), 4-2 | Wrigley Field (29-19) | 52-43 | |
| » Starters: Gary Gentry vs Fergie Jenkins | Second | 11 out |
| Wednesday, July 21 |
| » Defeated Mets (48-45), 11-7 | Wrigley Field (30-19) | 53-43 | Won 2 |
| » Starters: Charlie Williams vs Bill Hands | Second | 10 out |
| Thursday, July 22 |
| » Lost to Mets (49-45), 5-1 | Wrigley Field (30-20) | 53-44 | |
| » Starters: Tom Seaver vs Milt Pappas | Second | 10 out |
| Friday, July 23 |
| » Lost to Phillies (43-56), 4-3 | Veteran's Stadium (3-1) | 53-45 | Lost 2 |
| » Starters: Ken Holtzman vs Ken Reynolds | Second | 11 out |
| Saturday, July 24 |
| » Defeated Phillies (43-57), 2-1 | Veteran's Stadium (4-1) | 54-45 | |
| » Starters: Fergie Jenkins vs Rick Wise | Second | 11 out |
| Sunday, July 25 |
| » Lost to Phillies (44-57), 2-1 | Veteran's Stadium (4-2) | 54-46 | |
| » Starters: Bill Hands vs Chris Short | Second | 10½ out |
| Monday, July 26 |
| » Defeated Expos (40-62), 5-2 | Parc Jarry (2-2) | 55-46 | |
| » Starters: Milt Pappas vs Steve Renko | Second | 10 out |
| Tuesday, July 27 |
| » Lost to Expos (41-62), 6-1 | Parc Jarry (2-3) | 55-47 | |
| » Starters: Ken Holtzman vs Ernie McAnally | Second | 10 out |
| Wednesday, July 28 |
| » Defeated Expos (41-63), 10-2 | Parc Jarry (3-3) | 56-47 | |
| » Starters: Fergie Jenkins vs Carl Morton | Second | 10 out |
| Friday, July 30 |
| » Lost to Mets (53-49), 4-0 | Shea Stadium (1-3) | 56-48 | |
| » Starters: Bill Hands vs Gary Gentry | Third | 10½ out |
| Saturday, July 31 |
| » Lost to Mets (54-49), 5-2 | Shea Stadium (1-4) | 56-49 | Lost 2 |
| » Starters: Milt Pappas vs Ray Sadecki | Third | 10½ out |
| Sunday, August 1 |
| » Defeated Mets (54-50), 3-2 | Shea Stadium (2-4) | 57-49 | |
| » Starters: Juan Pizarro vs Tom Seaver | Third | 9 out |
| Monday, August 2 |
| » Lost to Astros (55-53), 2-1 | Astrodome (1-4) | 57-50 | |
| » Starters: Fergie Jenkins vs Don Wilson | Third | 9½ out |
| Tuesday, August 3 |
| » Defeated Astros (55-54), 5-0 | Astrodome (2-4) | 58-50 | |
| » Starters: Bill Hands vs Larry Dierker | Third | 9½ out |
| Wednesday, August 4 |
| » Defeated Padres (40-73), 3-0 | Wrigley Field (31-20) | 59-50 | Won 2 |
| » Starters: Fred Norman vs Milt Pappas | Third | 8½ out |
| Thursday, August 5 |
| » Defeated Padres (40-74), 3-0 | Wrigley Field (32-20) | 60-50 | Won 3 |
| » Starters: Clay Kirby vs Juan Pizarro | Third | 8½ out |
| Saturday, August 7 |
| » Defeated Giants (67-49), 6-5 | Wrigley Field (33-20) | 61-50 | Won 4 |
| » Starters: Don Carrithers vs Fergie Jenkins | Third | 7 out |
| Sunday, August 8 |
| » Lost to Giants (68-49), 4-2 | Wrigley Field (33-21) | 61-51 | |
| » Starters: Gaylord Perry vs Bill Hands | Third | 7 out |
| » Defeated Giants (68-50), 8-0 | Wrigley Field (34-21) | 62-51 | |
| » Starters: Ron Bryant vs Milt Pappas | Third | 7 out |
| Monday, August 9 |
| Future Cub Ben Van Ryn is born in Fort Wayne, IN. |
| Tuesday, August 10 |
| » Defeated Pirates (70-46), 2-1 | Three Rivers Stadium (2-3) | 63-51 | Won 2 |
| » Starters: Juan Pizarro vs Bruce Kison | Second | 6 out |
| Wednesday, August 11 |
| » Lost to Pirates (71-46), 3-2 | Three Rivers Stadium (2-4) | 63-52 | |
| » Starters: Fergie Jenkins vs Dock Ellis | Second | 7 out |
| Friday, August 13 |
| » Lost to Reds (56-64), 8-2 | Riverfront Stadium (3-1) | 63-53 | Lost 2 |
| » Starters: Bill Hands vs Don Gullett | Third | 6½ out |
| Saturday, August 14 |
| » Defeated Reds (56-65), 3-1 | Riverfront Stadium (4-1) | 64-53 | |
| » Starters: Milt Pappas vs Jim McGlothlin | Third | 5½ out |
| Sunday, August 15 |
| » Lost to Reds (57-65), 5-1 | Riverfront Stadium (4-2) | 64-54 | |
| » Starters: Juan Pizarro vs Ross Grimsley | Third | 5½ out |
| Monday, August 16 |
| » Defeated Braves (64-61), 3-0 | Atlanta-Fulton County Stadium (3-1) | 65-54 | |
| » Starters: Fergie Jenkins vs Tom Kelley | Third | 5½ out |
| Tuesday, August 17 |
| » Lost to Braves (65-61), 5-4 | Atlanta-Fulton County Stadium (3-2) | 65-55 | |
| » Starters: Bill Hands vs Ron Reed | Third | 5½ out |
| Wednesday, August 18 |
| » Defeated Braves (65-62), 7-2 | Atlanta-Fulton County Stadium (4-2) | 66-55 | |
| » Starters: Milt Pappas vs Phil Niekro | Second | 5½ out |
| Friday, August 20 |
| » Defeated Astros (61-63), 3-2 | Wrigley Field (35-21) | 67-55 | Won 2 |
| » Starters: Ron Cook vs Fergie Jenkins | Second | 4½ out |
| » Defeated Astros (61-64), 5-4 | Wrigley Field (36-21) | 68-55 | Won 3 |
| » Starters: Ken Forsch vs Ken Holtzman | Second | 4½ out |
| » Major-league debuts: Gene Hiser (Cubs) |
| Saturday, August 21 |
| » Lost to Astros (62-64), 3-0 | Wrigley Field (36-22) | 68-56 | |
| » Starters: Jack Billingham vs Bill Hands | Second | 4½ out |
| Sunday, August 22 |
| » Lost to Astros (63-64), 4-3 | Wrigley Field (36-23) | 68-57 | Lost 2 |
| » Starters: Wade Blasingame vs Milt Pappas | Second | 4½ out |
| Monday, August 23 |
| » Defeated Reds (63-67), 6-3 | Wrigley Field (37-23) | 69-57 | |
| » Starters: Don Gullett vs Juan Pizarro | Second | 5 out |
| Tuesday, August 24 |
| » Lost to Reds (64-67), 5-4 | Wrigley Field (37-24) | 69-58 | |
| » Starters: Jim McGlothlin vs Fergie Jenkins | Third | 5 out |
| Wednesday, August 25 |
| » Lost to Reds (65-67), 9-4 | Wrigley Field (37-25) | 69-59 | Lost 2 |
| » Starters: Ross Grimsley vs Bill Hands | Third | 6 out |
| Friday, August 27 |
| » Defeated Braves (68-67), 3-0 | Wrigley Field (38-25) | 70-59 | |
| » Starters: Ron Reed vs Milt Pappas | Third | 6 out |
| Saturday, August 28 |
| » Lost to Braves (69-67), 4-3 | Wrigley Field (38-26) | 70-60 | |
| » Starters: Phil Niekro vs Fergie Jenkins | Third | 6 out |
| Future Cub Shane Andrews is born in Dallas, TX. |
| Sunday, August 29 |
| » Lost to Braves (70-67), 5-4 | Wrigley Field (38-27) | 70-61 | Lost 2 |
| » Starters: Tom Kelley vs Juan Pizarro | Third | 7 out |
| Monday, August 30 |
| » Lost to Expos (56-74), 6-2 | Wrigley Field (38-28) | 70-62 | Lost 3 |
| » Starters: Steve Renko vs Bill Hands | Third | 8 out |
| Tuesday, August 31 |
| » Defeated Expos (56-75), 7-6 | Wrigley Field (39-28) | 71-62 | |
| » Starters: Carl Morton vs Milt Pappas | Third | 8½ out |
| » Lost to Expos (57-75), 11-2 | Wrigley Field (39-29) | 71-63 | |
| » Starters: John Strohmayer vs Ken Holtzman | Third | 8½ out |
| Wednesday, September 1 |
| » Defeated Expos (57-76), 5-2 | Wrigley Field (40-29) | 72-63 | |
| » Starters: Bill Stoneman vs Fergie Jenkins | Third | 8½ out |
| Thursday, September 2 |
| » Lost to Expos (58-76), 9-5 | Wrigley Field (40-30) | 72-64 | |
| » Starters: Ernie McAnally vs Juan Pizarro | Third | 9 out |
| Friday, September 3 |
| » Lost to Cardinals (77-61), 6-1 | Busch Stadium II (3-4) | 72-65 | Lost 2 |
| » Starters: Bill Hands vs Reggie Cleveland | Third | 9 out |
| » Major-league debuts: Billy North (Cubs) |
| Saturday, September 4 |
| » Defeated Cardinals (77-62), 7-5 | Busch Stadium II (4-4) | 73-65 | |
| » Starters: Milt Pappas vs Steve Carlton | Third | 9 out |
| Sunday, September 5 |
| » Lost to Cardinals (78-62), 12-5 | Busch Stadium II (4-5) | 73-66 | |
| » Starters: Fergie Jenkins vs Jerry Reuss | Third | 10 out |
| Monday, September 6 |
| » Lost to Pirates (85-57), 4-1 | Three Rivers Stadium (2-5) | 73-67 | Lost 2 |
| » Starters: Juan Pizarro vs Nelson Briles | Third | 12 out |
| » Lost to Pirates (86-57), 10-5 | Three Rivers Stadium (2-6) | 73-68 | Lost 3 |
| » Starters: Ken Holtzman vs Luke Walker | Third | 12 out |
| » Major-league debuts: Pat Bourque (Cubs) |
| Wednesday, September 8 |
| » Lost to Pirates (87-57), 10-1 | Three Rivers Stadium (2-7) | 73-69 | Lost 4 |
| » Starters: Milt Pappas vs Steve Blass | Third | 13 out |
| » Major-league debuts: Richie Zisk (Pirates) |
| Friday, September 10 |
| » Lost to Cardinals (81-63), 8-7 | Wrigley Field (40-31) | 73-70 | Lost 5 |
| » Starters: Steve Carlton vs Fergie Jenkins | Fourth | 13 out |
| Saturday, September 11 |
| » Defeated Cardinals (81-64), 7-0 | Wrigley Field (41-31) | 74-70 | |
| » Starters: Jerry Reuss vs Juan Pizarro | Fourth | 12 out |
| Sunday, September 12 |
| » Lost to Cardinals (82-64), 4-0 | Wrigley Field (41-32) | 74-71 | |
| » Starters: Bob Gibson vs Ken Holtzman | Fourth | 13 out |
| Monday, September 13 |
| » Lost to Pirates (89-59), 5-1 | Wrigley Field (41-33) | 74-72 | Lost 2 |
| » Starters: Steve Blass vs Milt Pappas | Fourth | 14 out |
| Tuesday, September 14 |
| » Lost to Pirates (90-59), 4-3 | Wrigley Field (41-34) | 74-73 | Lost 3 |
| » Starters: Bob Johnson vs Fergie Jenkins | Fourth | 15 out |
| Wednesday, September 15 |
| » Defeated Mets (77-71), 6-2 | Shea Stadium (3-4) | 75-73 | |
| » Starters: Bill Hands vs Jerry Koosman | Fourth | 14½ out |
| » Defeated Mets (77-72), 3-2 | Shea Stadium (4-4) | 76-73 | Won 2 |
| » Starters: Burt Hooton vs Tug McGraw | Fourth | 14½ out |
| » Major-league debuts: Buzz Capra, John Milner and Don Rose (Mets) |
| Future Cub Jason Hardtke is born in Milwaukee, WI. |
| Thursday, September 16 |
| » Defeated Mets (77-73), 1-0 | Shea Stadium (5-4) | 77-73 | Won 3 |
| » Starters: Juan Pizarro vs Tom Seaver | Third | 14½ out |
| Friday, September 17 |
| » Defeated Phillies (61-90), 4-3 | Veteran's Stadium (5-2) | 78-73 | Won 4 |
| » Starters: Joe Decker vs Ken Reynolds | Third | 13½ out |
| Former Cub Hack Miller dies in Oakland, CA at the age of 78. |
| Saturday, September 18 |
| » Lost to Phillies (62-90), 4-3 | Veteran's Stadium (5-3) | 78-74 | |
| » Starters: Milt Pappas vs Rick Wise | Third | 14½ out |
| Sunday, September 19 |
| » Defeated Phillies (62-91), 6-3 | Veteran's Stadium (6-3) | 79-74 |
