| Thursday, January 7 |
| Future Athletic Frank Menechino is born in Staten Island, NY. |
| Friday, January 8 |
| Future Athletic Jason Giambi is born in West Covina, CA. |
| Thursday, January 21 |
| Future Athletic Johnny Guzman is born in Hatillo Palma, D.R. |
| Friday, March 5 |
| Future Athletic Brian Lesher is born in Wilrijk, Belgium. |
| Monday, April 5 |
| » Lost to Senators (1-0), 8-0 | Robert F. Kennedy Stadium (0-1) | 0-1 | |
| » Starters: Vida Blue vs Dick Bosman | Second | ½ out |
| Wednesday, April 7 |
| » Lost to White Sox (1-0), 6-5 | Oakland-Alameda County Stadium (0-1) | 0-2 | Lost 2 |
| » Starters: Tommy John vs Catfish Hunter | Third | 2½ out |
| » Lost to White Sox (2-0), 12-4 | Oakland-Alameda County Stadium (0-2) | 0-3 | Lost 3 |
| » Starters: Bart Johnson vs Rollie Fingers | Third | 2½ out |
| » Major-league debuts: Lee Richard (White Sox) |
| Friday, April 9 |
| » Defeated Royals (2-2), 5-0 | Oakland-Alameda County Stadium (1-2) | 1-3 | |
| » Starters: Jim Rooker vs Vida Blue | Fifth | 2½ out |
| Saturday, April 10 |
| » Defeated Royals (2-3), 5-4 | Oakland-Alameda County Stadium (2-2) | 2-3 | Won 2 |
| » Starters: Bruce DalCanton vs Diego Segui | Fourth | 1½ out |
| Sunday, April 11 |
| » Lost to Royals (3-3), 10-5 | Oakland-Alameda County Stadium (2-3) | 2-4 | |
| » Starters: Al Fitzmorris vs Catfish Hunter | Fourth | 2 out |
| Monday, April 12 |
| » Defeated Brewers (3-2), 5-0 | County Stadium (1-0) | 3-4 | |
| » Starters: Rollie Fingers vs Lew Krausse | Fourth | 1½ out |
| » Major-league debuts: Ron Theobald (Brewers) |
| Tuesday, April 13 |
| » Defeated Brewers (3-3), 2-0 | County Stadium (2-0) | 4-4 | Won 2 |
| » Starters: Vida Blue vs Bill Parsons | Third | ½ out |
| » Major-league debuts: Rick Auerbach and Bill Parsons (Brewers) |
| Wednesday, April 14 |
| » Defeated Twins (4-4), 6-1 | Metropolitan Stadium (1-0) | 5-4 | Won 3 |
| » Starters: Diego Segui vs Tom Hall | Second | 1 out |
| Thursday, April 15 |
| » Defeated Twins (4-5), 4-3 | Metropolitan Stadium (2-0) | 6-4 | Won 4 |
| » Starters: Catfish Hunter vs Jim Kaat | Second | 1 out |
| Friday, April 16 |
| » Defeated White Sox (3-7), 5-4 | Comiskey Park I (1-0) | 7-4 | Won 5 |
| » Starters: Rob Gardner vs Wilbur Wood | First | -- |
| Saturday, April 17 |
| » Lost to White Sox (4-7), 4-0 | Comiskey Park I (1-1) | 7-5 | |
| » Starters: Rollie Fingers vs Tom Bradley | Second | ½ out |
| Sunday, April 18 |
| » Defeated White Sox (4-8), 11-2 | Comiskey Park I (2-1) | 8-5 | |
| » Starters: Vida Blue vs Tommy John | Second | 1 out |
| » Defeated White Sox (4-9), 6-1 | Comiskey Park I (3-1) | 9-5 | Won 2 |
| » Starters: Diego Segui vs Terry Forster | Second | 1 out |
| Tuesday, April 20 |
| » Defeated Angels (8-5), 4-0 | Anaheim Stadium (1-0) | 10-5 | Won 3 |
| » Starters: Catfish Hunter vs Tom Murphy | First | -- |
| Wednesday, April 21 |
| » Defeated Angels (8-6), 4-2 | Anaheim Stadium (2-0) | 11-5 | Won 4 |
| » Starters: Rollie Fingers vs Rudy May | First | -- |
| Thursday, April 22 |
| » Defeated Angels (8-7), 7-3 | Anaheim Stadium (3-0) | 12-5 | Won 5 |
| » Starters: Vida Blue vs Andy Messersmith | First | -- |
| Friday, April 23 |
| » Defeated Tigers (6-8), 9-2 | Oakland-Alameda County Stadium (3-3) | 13-5 | Won 6 |
| » Starters: Dean Chance vs Diego Segui | First | -- |
| Saturday, April 24 |
| » Defeated Tigers (6-9), 5-4 | Oakland-Alameda County Stadium (4-3) | 14-5 | Won 7 |
| » Starters: Joe Coleman vs Catfish Hunter | First | -- |
| Sunday, April 25 |
| » Lost to Tigers (7-9), 10-2 | Oakland-Alameda County Stadium (4-4) | 14-6 | |
| » Starters: Mickey Lolich vs Rollie Fingers | First | -- |
| Monday, April 26 |
| » Defeated Orioles (10-6), 1-0 | Oakland-Alameda County Stadium (5-4) | 15-6 | |
| » Starters: Pat Dobson vs Vida Blue | First | -- |
| Tuesday, April 27 |
| » Lost to Orioles (11-6), 6-2 | Oakland-Alameda County Stadium (5-5) | 15-7 | |
| » Starters: Dave McNally vs Diego Segui | First | -- |
| Wednesday, April 28 |
| » Defeated Orioles (11-7), 5-4 | Oakland-Alameda County Stadium (6-5) | 16-7 | |
| » Starters: Mike Cuellar vs Catfish Hunter | First | -- |
| Thursday, April 29 |
| » Lost to Orioles (12-7), 3-2 | Oakland-Alameda County Stadium (6-6) | 16-8 | |
| » Starters: Jim Palmer vs Rollie Fingers | First | -- |
| Friday, April 30 |
| » Defeated Indians (6-14), 3-1 | Oakland-Alameda County Stadium (7-6) | 17-8 | |
| » Starters: Steve Hargan vs Vida Blue | First | -- |
| Saturday, May 1 |
| » Lost to Indians (7-14), 2-1 | Oakland-Alameda County Stadium (7-7) | 17-9 | |
| » Starters: Steve Dunning vs Diego Segui | First | -- |
| Sunday, May 2 |
| » Defeated Indians (7-15), 8-5 | Oakland-Alameda County Stadium (8-7) | 18-9 | |
| » Starters: Sam McDowell vs Catfish Hunter | First | -- |
| » Lost to Indians (8-15), 7-3 | Oakland-Alameda County Stadium (8-8) | 18-10 | |
| » Starters: Ray Lamb vs Chuck Dobson | First | -- |
| Tuesday, May 4 |
| » Lost to Tigers (11-12), 6-5 | Tiger Stadium (0-1) | 18-11 | Lost 2 |
| » Starters: Rollie Fingers vs Joe Coleman | First | -- |
| Wednesday, May 5 |
| » Defeated Tigers (11-13), 5-0 | Tiger Stadium (1-1) | 19-11 | |
| » Starters: Vida Blue vs Dean Chance | First | -- |
| Sunday, May 9 |
| » Defeated Orioles (16-10), 6-2 | Memorial Stadium (1-0) | 20-11 | Won 2 |
| » Starters: Catfish Hunter vs Mike Cuellar | First | -- |
| » Defeated Orioles (16-11), 2-1 | Memorial Stadium (2-0) | 21-11 | Won 3 |
| » Starters: Vida Blue vs Jim Palmer | First | -- |
| Tuesday, May 11 |
| » Lost to Indians (10-19), 7-5 | Cleveland Stadium (0-1) | 21-12 | |
| » Starters: Diego Segui vs Steve Dunning | First | -- |
| Wednesday, May 12 |
| » Defeated Indians (10-20), 8-1 | Cleveland Stadium (1-1) | 22-12 | |
| » Starters: Chuck Dobson vs Sam McDowell | First | -- |
| Thursday, May 13 |
| » Defeated Royals (16-17), 6-3 | Municipal Stadium (1-0) | 23-12 | Won 2 |
| » Starters: Catfish Hunter vs Wally Bunker | First | -- |
| Friday, May 14 |
| » Defeated Royals (16-18), 5-3 | Municipal Stadium (2-0) | 24-12 | Won 3 |
| » Starters: Vida Blue vs Ken Wright | First | -- |
| Saturday, May 15 |
| » Lost to Royals (17-18), 5-4 | Municipal Stadium (2-1) | 24-13 | |
| » Starters: Rollie Fingers vs Bruce DalCanton | First | -- |
| Sunday, May 16 |
| » Defeated Royals (17-19), 4-2 | Municipal Stadium (3-1) | 25-13 | |
| » Starters: Chuck Dobson vs Dick Drago | First | -- |
| » Lost to Royals (18-19), 10-4 | Municipal Stadium (3-2) | 25-14 | |
| » Starters: Blue Moon Odom vs Mike McCormick | First | -- |
| Tuesday, May 18 |
| » Defeated Brewers (14-19), 5-2 | Oakland-Alameda County Stadium (9-8) | 26-14 | |
| » Starters: Marty Pattin vs Catfish Hunter | First | -- |
| Wednesday, May 19 |
| » Defeated Brewers (14-20), 3-0 | Oakland-Alameda County Stadium (10-8) | 27-14 | Won 2 |
| » Starters: Bill Parsons vs Vida Blue | First | -- |
| Thursday, May 20 |
| » Defeated Brewers (14-21), 7-3 | Oakland-Alameda County Stadium (11-8) | 28-14 | Won 3 |
| » Starters: Lew Krausse vs Chuck Dobson | First | -- |
| Friday, May 21 |
| » Lost to Twins (21-19), 10-1 | Oakland-Alameda County Stadium (11-9) | 28-15 | |
| » Starters: Bert Blyleven vs Blue Moon Odom | First | -- |
| Saturday, May 22 |
| » Defeated Twins (21-20), 5-1 | Oakland-Alameda County Stadium (12-9) | 29-15 | |
| » Starters: Jim Kaat vs Catfish Hunter | First | -- |
| Sunday, May 23 |
| » Defeated Twins (21-21), 3-1 | Oakland-Alameda County Stadium (13-9) | 30-15 | Won 2 |
| » Starters: Jim Perry vs Vida Blue | First | -- |
| Tuesday, May 25 |
| » Defeated Angels (21-24), 7-5 | Oakland-Alameda County Stadium (14-9) | 31-15 | Won 3 |
| » Starters: Clyde Wright vs Chuck Dobson | First | -- |
| Wednesday, May 26 |
| » Lost to Angels (22-24), 7-5 | Oakland-Alameda County Stadium (14-10) | 31-16 | |
| » Starters: Tom Murphy vs Catfish Hunter | First | -- |
| Friday, May 28 |
| » Lost to Red Sox (29-15), 4-3 | Fenway Park (0-1) | 31-17 | Lost 2 |
| » Starters: Vida Blue vs Sonny Siebert | First | -- |
| Saturday, May 29 |
| » Defeated Red Sox (29-16), 12-8 | Fenway Park (1-1) | 32-17 | |
| » Starters: Chuck Dobson vs Jim Lonborg | First | -- |
| Monday, May 31 |
| » Lost to Yankees (21-25), 5-3 | Yankee Stadium (0-1) | 32-18 | |
| » Starters: Catfish Hunter vs Fritz Peterson | First | -- |
| » Defeated Yankees (21-26), 6-3 | Yankee Stadium (1-1) | 33-18 | |
| » Starters: Blue Moon Odom vs Mike Kekich | First | -- |
| Tuesday, June 1 |
| » Defeated Yankees (21-27), 5-2 | Yankee Stadium (2-1) | 34-18 | Won 2 |
| » Starters: Vida Blue vs Steve Kline | First | -- |
| Thursday, June 3 |
| Future Athletic Izzy Molina is born in New York, NY. |
| Friday, June 4 |
| » Defeated Senators (19-31), 5-3 | Robert F. Kennedy Stadium (1-1) | 35-18 | Won 3 |
| » Starters: Chuck Dobson vs Jerry Janeski | First | -- |
| Saturday, June 5 |
| » Defeated Senators (19-32), 6-1 | Robert F. Kennedy Stadium (2-1) | 36-18 | Won 4 |
| » Starters: Catfish Hunter vs Dick Bosman | First | -- |
| Sunday, June 6 |
| » Defeated Senators (19-33), 8-1 | Robert F. Kennedy Stadium (3-1) | 37-18 | Won 5 |
| » Starters: Vida Blue vs Denny McLain | First | -- |
| Tuesday, June 8 |
| » Lost to Red Sox (32-22), 5-1 | Oakland-Alameda County Stadium (14-11) | 37-19 | |
| » Starters: Ray Culp vs Blue Moon Odom | First | -- |
| Wednesday, June 9 |
| » Defeated Red Sox (32-23), 6-1 | Oakland-Alameda County Stadium (15-11) | 38-19 | |
| » Starters: Gary Peters vs Chuck Dobson | First | -- |
| Friday, June 11 |
| » Lost to Yankees (26-31), 6-4 | Oakland-Alameda County Stadium (15-12) | 38-20 | |
| » Starters: Steve Kline vs Catfish Hunter | First | -- |
| Saturday, June 12 |
| » Defeated Yankees (26-32), 13-3 | Oakland-Alameda County Stadium (16-12) | 39-20 | |
| » Starters: Mel Stottlemyre vs Vida Blue | First | -- |
| Sunday, June 13 |
| » Lost to Yankees (27-32), 5-1 | Oakland-Alameda County Stadium (16-13) | 39-21 | |
| » Starters: Fritz Peterson vs Blue Moon Odom | First | -- |
| Tuesday, June 15 |
| » Defeated Senators (21-37), 8-2 | Oakland-Alameda County Stadium (17-13) | 40-21 | |
| » Starters: Jerry Janeski vs Chuck Dobson | First | -- |
| Wednesday, June 16 |
| » Defeated Senators (21-38), 5-1 | Oakland-Alameda County Stadium (18-13) | 41-21 | Won 2 |
| » Starters: Denny McLain vs Vida Blue | First | -- |
| » Major-league debuts: Lenny Randle (Senators) |
| Friday, June 18 |
| » Defeated Brewers (22-36), 6-2 | County Stadium (3-0) | 42-21 | Won 3 |
| » Starters: Catfish Hunter vs Skip Lockwood | First | -- |
| » Major-league debuts: Rob Ellis (Brewers) |
| Saturday, June 19 |
| » Defeated Brewers (22-37), 2-0 | County Stadium (4-0) | 43-21 | Won 4 |
| » Starters: Blue Moon Odom vs Bill Parsons | First | -- |
| Sunday, June 20 |
| » Defeated Brewers (22-38), 11-4 | County Stadium (5-0) | 44-21 | Won 5 |
| » Starters: Chuck Dobson vs Jim Slaton | First | -- |
| » Lost to Brewers (23-38), 7-4 | County Stadium (5-1) | 44-22 | |
| » Starters: Diego Segui vs Marcelino Lopez | First | -- |
| Monday, June 21 |
| » Defeated Twins (34-34), 3-2 | Metropolitan Stadium (3-0) | 45-22 | |
| » Starters: Vida Blue vs Ray Corbin | First | -- |
| Tuesday, June 22 |
| » Lost to Twins (35-34), 10-1 | Metropolitan Stadium (3-1) | 45-23 | |
| » Starters: Catfish Hunter vs Jim Perry | First | -- |
| Wednesday, June 23 |
| » Defeated Twins (35-35), 8-3 | Metropolitan Stadium (4-1) | 46-23 | |
| » Starters: Blue Moon Odom vs Bert Blyleven | First | -- |
| Friday, June 25 |
| » Defeated Royals (35-31), 7-0 | Oakland-Alameda County Stadium (19-13) | 47-23 | Won 2 |
| » Starters: Mike Hedlund vs Vida Blue | First | -- |
| Saturday, June 26 |
| » Defeated Royals (35-32), 4-2 | Oakland-Alameda County Stadium (20-13) | 48-23 | Won 3 |
| » Starters: Bruce DalCanton vs Catfish Hunter | First | -- |
| Sunday, June 27 |
| » Defeated Royals (35-33), 3-0 | Oakland-Alameda County Stadium (21-13) | 49-23 | Won 4 |
| » Starters: Dick Drago vs Blue Moon Odom | First | -- |
| » Lost to Royals (36-33), 6-3 | Oakland-Alameda County Stadium (21-14) | 49-24 | |
| » Starters: Bill Butler vs Diego Segui | First | -- |
| Monday, June 28 |
| » Defeated Twins (36-39), 6-4 | Oakland-Alameda County Stadium (22-14) | 50-24 | |
| » Starters: Bert Blyleven vs Chuck Dobson | First | -- |
| Future Athletic Ron Mahay is born in Crestwood, IL. |
| Tuesday, June 29 |
| » Lost to Twins (37-39), 5-3 | Oakland-Alameda County Stadium (22-15) | 50-25 | |
| » Starters: Ray Corbin vs Vida Blue | First | -- |
| Wednesday, June 30 |
| » Lost to Twins (38-39), 10-4 | Oakland-Alameda County Stadium (22-16) | 50-26 | Lost 2 |
| » Starters: Jim Perry vs Catfish Hunter | First | -- |
| Friday, July 2 |
| » Lost to Angels (36-46), 1-0 | Anaheim Stadium (3-1) | 50-27 | Lost 3 |
| » Starters: Blue Moon Odom vs Rickey Clark | First | -- |
| Saturday, July 3 |
| » Defeated Angels (36-47), 5-3 | Anaheim Stadium (4-1) | 51-27 | |
| » Starters: Chuck Dobson vs Clyde Wright | First | -- |
| Sunday, July 4 |
| » Defeated Angels (36-48), 2-1 | Anaheim Stadium (5-1) | 52-27 | Won 2 |
| » Starters: Vida Blue vs Tom Murphy | First | -- |
| Monday, July 5 |
| » Lost to Angels (37-48), 2-1 | Anaheim Stadium (5-2) | 52-28 | |
| » Starters: Catfish Hunter vs Rudy May | First | -- |
| Tuesday, July 6 |
| » Defeated White Sox (34-45), 9-4 | Comiskey Park I (4-1) | 53-28 | |
| » Starters: Diego Segui vs Jim Magnuson | First | -- |
| Wednesday, July 7 |
| » Lost to White Sox (35-45), 2-1 | Comiskey Park I (4-2) | 53-29 | |
| » Starters: Blue Moon Odom vs Tommy John | First | -- |
| Thursday, July 8 |
| » Defeated White Sox (35-46), 4-2 | Comiskey Park I (5-2) | 54-29 | |
| » Starters: Chuck Dobson vs Wilbur Wood | First | -- |
| Friday, July 9 |
| » Defeated Angels (40-49), 1-0 | Oakland-Alameda County Stadium (23-16) | 55-29 | Won 2 |
| » Starters: Rudy May vs Vida Blue | First | -- |
| Saturday, July 10 |
| » Lost to Angels (41-49), 3-0 | Oakland-Alameda County Stadium (23-17) | 55-30 | |
| » Starters: Andy Messersmith vs Catfish Hunter | First | -- |
| Sunday, July 11 |
| » Defeated Angels (41-50), 3-2 | Oakland-Alameda County Stadium (24-17) | 56-30 | |
| » Starters: Rickey Clark vs Diego Segui | First | -- |
| » Lost to Angels (42-50), 6-3 | Oakland-Alameda County Stadium (24-18) | 56-31 | |
| » Starters: Clyde Wright vs Blue Moon Odom | First | -- |
| Thursday, July 15 |
| » Defeated Tigers (47-40), 8-7 | Oakland-Alameda County Stadium (25-18) | 57-31 | |
| » Starters: Mickey Lolich vs Chuck Dobson | First | -- |
| Friday, July 16 |
| » Defeated Tigers (47-41), 4-0 | Oakland-Alameda County Stadium (26-18) | 58-31 | Won 2 |
| » Starters: Les Cain vs Vida Blue | First | -- |
| Saturday, July 17 |
| » Lost to Tigers (48-41), 2-1 | Oakland-Alameda County Stadium (26-19) | 58-32 | |
| » Starters: Joe Coleman vs Catfish Hunter | First | -- |
| Sunday, July 18 |
| » Lost to Orioles (57-34), 7-3 | Oakland-Alameda County Stadium (26-20) | 58-33 | Lost 2 |
| » Starters: Grant Jackson vs Blue Moon Odom | First | -- |
| Monday, July 19 |
| » Lost to Orioles (58-34), 4-2 | Oakland-Alameda County Stadium (26-21) | 58-34 | Lost 3 |
| » Starters: Pat Dobson vs Diego Segui | First | -- |
| Tuesday, July 20 |
| » Defeated Indians (40-55), 6-3 | Oakland-Alameda County Stadium (27-21) | 59-34 | |
| » Starters: Ray Lamb vs Chuck Dobson | First | -- |
| Wednesday, July 21 |
| » Defeated Indians (40-56), 4-3 | Oakland-Alameda County Stadium (28-21) | 60-34 | Won 2 |
| » Starters: Steve Dunning vs Vida Blue | First | -- |
| Friday, July 23 |
| » Defeated Tigers (50-46), 9-7 | Tiger Stadium (2-1) | 61-34 | Won 3 |
| » Starters: Catfish Hunter vs Mickey Lolich | First | -- |
| Saturday, July 24 |
| » Defeated Tigers (50-47), 7-2 | Tiger Stadium (3-1) | 62-34 | Won 4 |
| » Starters: Blue Moon Odom vs Les Cain | First | -- |
| Sunday, July 25 |
| » Lost to Tigers (51-47), 7-4 | Tiger Stadium (3-2) | 62-35 | |
| » Starters: Chuck Dobson vs Joe Coleman | First | -- |
| » Defeated Tigers (51-48), 6-1 | Tiger Stadium (4-2) | 63-35 | |
| » Starters: Vida Blue vs Bill Denehy | First | -- |
| Tuesday, July 27 |
| » Lost to Orioles (61-38), 1-0 | Memorial Stadium (2-1) | 63-36 | |
| » Starters: Catfish Hunter vs Pat Dobson | First | -- |
| » Lost to Orioles (62-38), 6-4 | Memorial Stadium (2-2) | 63-37 | Lost 2 |
| » Starters: Diego Segui vs Grant Jackson | First | -- |
| Wednesday, July 28 |
| » Lost to Orioles (63-38), 3-2 | Memorial Stadium (2-3) | 63-38 | Lost 3 |
| » Starters: Blue Moon Odom vs Mike Cuellar | First | -- |
| Friday, July 30 |
| » Lost to Indians (43-61), 4-1 | Cleveland Stadium (1-2) | 63-39 | Lost 4 |
| » Starters: Vida Blue vs Alan Foster | First | -- |
| Saturday, July 31 |
| » Defeated Indians (43-62), 9-1 | Cleveland Stadium (2-2) | 64-39 | |
| » Starters: Chuck Dobson vs Steve Dunning | First | -- |
| Sunday, August 1 |
| » Defeated Indians (43-63), 7-3 | Cleveland Stadium (3-2) | 65-39 | Won 2 |
| » Starters: Catfish Hunter vs Steve Hargan | First | -- |
| » Defeated Indians (43-64), 4-2 | Cleveland Stadium (4-2) | 66-39 | Won 3 |
| » Starters: Blue Moon Odom vs Vince Colbert | First | -- |
| Monday, August 2 |
| » Defeated Royals (52-51), 2-1 | Municipal Stadium (4-2) | 67-39 | Won 4 |
| » Starters: Diego Segui vs Paul Splittorff | First | -- |
| Tuesday, August 3 |
| » Defeated Royals (52-52), 7-5 | Municipal Stadium (5-2) | 68-39 | Won 5 |
| » Starters: Vida Blue vs Ken Wright | First | -- |
| Wednesday, August 4 |
| » Defeated Brewers (46-62), 6-5 | Oakland-Alameda County Stadium (29-21) | 69-39 | Won 6 |
| » Starters: Marcelino Lopez vs Chuck Dobson | First | -- |
| Thursday, August 5 |
| » Defeated Brewers (46-63), 2-1 | Oakland-Alameda County Stadium (30-21) | 70-39 | Won 7 |
| » Starters: Bill Parsons vs Catfish Hunter | First | -- |
| Friday, August 6 |
| » Lost to White Sox (53-58), 7-0 | Oakland-Alameda County Stadium (30-22) | 70-40 | |
| » Starters: Tom Bradley vs Blue Moon Odom | First | -- |
| Saturday, August 7 |
| » Defeated White Sox (53-59), 1-0 | Oakland-Alameda County Stadium (31-22) | 71-40 | |
| » Starters: Joe Horlen vs Vida Blue | First | -- |
| Sunday, August 8 |
| » Lost to White Sox (54-59), 9-7 | Oakland-Alameda County Stadium (31-23) | 71-41 | |
| » Starters: Tommy John vs Chuck Dobson | First | -- |
| » Lost to White Sox (55-59), 3-1 | Oakland-Alameda County Stadium (31-24) | 71-42 | Lost 2 |
| » Starters: Wilbur Wood vs Diego Segui | First | -- |
| Tuesday, August 10 |
| » Defeated Red Sox (64-50), 6-5 | Fenway Park (2-1) | 72-42 | |
| » Starters: Catfish Hunter vs Gary Peters | First | -- |
| » Defeated Red Sox (64-51), 7-5 | Fenway Park (3-1) | 73-42 | Won 2 |
| » Starters: Blue Moon Odom vs Ray Culp | First | -- |
| Future Athletic Sal Fasano is born in Chicago, IL. |
| Wednesday, August 11 |
| » Defeated Red Sox (64-52), 5-3 | Fenway Park (4-1) | 74-42 | Won 3 |
| » Starters: Vida Blue vs Sonny Siebert | First | -- |
| Thursday, August 12 |
| » Defeated Red Sox (64-53), 9-2 | Fenway Park (5-1) | 75-42 | Won 4 |
| » Starters: Diego Segui vs Ken Brett | First | -- |
| Friday, August 13 |
| » Defeated Yankees (60-59), 5-2 | Yankee Stadium (3-1) | 76-42 | Won 5 |
| » Starters: Chuck Dobson vs Mel Stottlemyre | First | -- |
| Saturday, August 14 |
| » Defeated Yankees (60-60), 1-0 | Yankee Stadium (4-1) | 77-42 | Won 6 |
| » Starters: Catfish Hunter vs Steve Kline | First | -- |
| Sunday, August 15 |
| » Defeated Yankees (60-61), 6-4 | Yankee Stadium (5-1) | 78-42 | Won 7 |
| » Starters: Vida Blue vs Stan Bahnsen | First | -- |
| Tuesday, August 17 |
| » Lost to Senators (50-70), 8-1 | Robert F. Kennedy Stadium (3-2) | 78-43 | |
| » Starters: Blue Moon Odom vs Bill Gogolewski | First | -- |
| Wednesday, August 18 |
| » Lost to Senators (51-70), 10-3 | Robert F. Kennedy Stadium (3-3) | 78-44 | Lost 2 |
| » Starters: Chuck Dobson vs Pete Broberg | First | -- |
| Friday, August 20 |
| » Lost to Red Sox (67-57), 1-0 | Oakland-Alameda County Stadium (31-25) | 78-45 | Lost 3 |
| » Starters: Gary Peters vs Vida Blue | First | -- |
| Saturday, August 21 |
| » Defeated Red Sox (67-58), 4-1 | Oakland-Alameda County Stadium (32-25) | 79-45 | |
| » Starters: Ray Culp vs Catfish Hunter | First | -- |
| Sunday, August 22 |
| » Defeated Red Sox (67-59), 9-3 | Oakland-Alameda County Stadium (33-25) | 80-45 | Won 2 |
| » Starters: Roger Moret vs Blue Moon Odom | First | -- |
| » Defeated Red Sox (67-60), 2-1 | Oakland-Alameda County Stadium (34-25) | 81-45 | Won 3 |
| » Starters: Sonny Siebert vs Diego Segui | First | -- |
| Monday, August 23 |
| » Defeated Yankees (63-65), 8-2 | Oakland-Alameda County Stadium (35-25) | 82-45 | Won 4 |
| » Starters: Mike Kekich vs Chuck Dobson | First | -- |
| Tuesday, August 24 |
| » Lost to Yankees (64-65), 1-0 | Oakland-Alameda County Stadium (35-26) | 82-46 | |
| » Starters: Mel Stottlemyre vs Vida Blue | First | -- |
| Wednesday, August 25 |
| » Lost to Yankees (65-65), 4-2 | Oakland-Alameda County Stadium (35-27) | 82-47 | Lost 2 |
| » Starters: Steve Kline vs Catfish Hunter | First | -- |
| Friday, August 27 |
| » Defeated Senators (55-74), 6-2 | Oakland-Alameda County Stadium (36-27) | 83-47 | |
| » Starters: Bill Gogolewski vs Blue Moon Odom | First | -- |
| Saturday, August 28 |
| » Defeated Senators (55-75), 10-6 | Oakland-Alameda County Stadium (37-27) | 84-47 | Won 2 |
| » Starters: Mike Thompson vs Chuck Dobson | First | -- |
| Sunday, August 29 |
| » Defeated Senators (55-76), 4-3 | Oakland-Alameda County Stadium (38-27) | 85-47 | Won 3 |
| » Starters: Pete Broberg vs Vida Blue | First | -- |
| » Defeated Senators (55-77), 9-0 | Oakland-Alameda County Stadium (39-27) | 86-47 | Won 4 |
| » Starters: Denny McLain vs Catfish Hunter | First | -- |
| Tuesday, August 31 |
| » Defeated Angels (63-72), 4-1 | Anaheim Stadium (6-2) | 87-47 | Won 5 |
| » Starters: Blue Moon Odom vs Tom Murphy | First | -- |
| Wednesday, September 1 |
| » Defeated Angels (63-73), 7-0 | Anaheim Stadium (7-2) | 88-47 | Won 6 |
| » Starters: Chuck Dobson vs Andy Messersmith | First | -- |
| Friday, September 3 |
| » Lost to Twins (61-72), 9-4 | Metropolitan Stadium (4-2) | 88-48 | |
| » Starters: Diego Segui vs Jim Perry | First | -- |
| » Lost to Twins (62-72), 2-1 | Metropolitan Stadium (4-3) | 88-49 | Lost 2 |
| » Starters: Vida Blue vs Ray Corbin | First | -- |
| » Major-league debuts: Eric Soderholm (Twins) Dwain Anderson (Athletics) |
| Saturday, September 4 |
| » Defeated Twins (62-73), 5-4 | Metropolitan Stadium (5-3) | 89-49 | |
| » Starters: Catfish Hunter vs Jim Kaat | First | -- |
| Sunday, September 5 |
| » Lost to Twins (63-73), 7-3 | Metropolitan Stadium (5-4) | 89-50 | |
| » Starters: Blue Moon Odom vs Bert Blyleven | First | -- |
| Monday, September 6 |
| » Lost to Angels (65-75), 4-2 | Oakland-Alameda County Stadium (39-28) | 89-51 | Lost 2 |
| » Starters: Andy Messersmith vs Chuck Dobson | First | -- |
| Tuesday, September 7 |
| » Lost to Angels (66-75), 6-1 | Oakland-Alameda County Stadium (39-29) | 89-52 | Lost 3 |
| » Starters: Clyde Wright vs Vida Blue | First | -- |
| Wednesday, September 8 |
| » Defeated Angels (66-76), 1-0 | Oakland-Alameda County Stadium (40-29) | 90-52 | |
| » Starters: Rudy May vs Catfish Hunter | First | -- |
| Friday, September 10 |
| » Defeated Twins (65-76), 5-4 | Oakland-Alameda County Stadium (41-29) | 91-52 | Won 2 |
| » Starters: Bert Blyleven vs Blue Moon Odom | First | -- |
| Saturday, September 11 |
| » Defeated Twins (65-77), 5-3 | Oakland-Alameda County Stadium (42-29) | 92-52 | Won 3 |
| » Starters: Ray Corbin vs Chuck Dobson | First | -- |
| Sunday, September 12 |
| » Lost to Twins (66-77), 7-5 | Oakland-Alameda County Stadium (42-30) | 92-53 | |
| » Starters: Jim Perry vs Vida Blue | First | -- |
| Monday, September 13 |
| » Defeated Royals (78-68), 2-1 | Municipal Stadium (6-2) | 93-53 | |
| » Starters: Catfish Hunter vs Al Fitzmorris | First | -- |
| Tuesday, September 14 |
| » Lost to Royals (79-68), 2-0 | Municipal Stadium (6-3) | 93-54 | |
| » Starters: Diego Segui vs Paul Splittorff | First | -- |
| » Major-league debuts: Monty Montgomery (Royals) |
| Wednesday, September 15 |
| » Defeated White Sox (69-79), 3-2 | Comiskey Park I (6-2) | 94-54 | |
| » Starters: Chuck Dobson vs Wilbur Wood | First | -- |
| » Lost to White Sox (70-79), 7-3 | Comiskey Park I (6-3) | 94-55 | |
| » Starters: Blue Moon Odom vs Tommy John | First | -- |
| Friday, September 17 |
| » Defeated Brewers (64-86), 6-5 | County Stadium (6-1) | 95-55 | |
| » Starters: Vida Blue vs Marty Pattin | First | -- |
| Saturday, September 18 |
| » Defeated Brewers (64-87), 4-2 | County Stadium (7-1) | 96-55 | Won 2 |
| » Starters: Catfish Hunter vs Jim Slaton | First | -- |
| Sunday, September 19 |
| » Defeated Brewers (64-88), 6-2 | County Stadium (8-1) | 97-55 | Won 3 |
| » Starters: Diego Segui vs Bill Parsons | First | -- |
| Tuesday, September 21 |
| » Lost to White Sox (73-80), 5-1 | Oakland-Alameda County Stadium (42-31) | 97-56 | |
| » Starters: Bart Johnson vs Chuck Dobson | First | -- |
| » Lost to White Sox (74-80), 6-2 | Oakland-Alameda County Stadium (42-32) | 97-57 | Lost 2 |
| » Starters: Tommy John vs Blue Moon Odom | First | -- |
| Wednesday, September 22 |
| » Lost to White Sox (75-80), 3-0 | Oakland-Alameda County Stadium (42-33) | 97-58 | Lost 3 |
| » Starters: Tom Bradley vs Vida Blue | First | -- |
| Thursday, September 23 |
| » Defeated Brewers (66-89), 5-4 | Oakland-Alameda County Stadium (43-33) | 98-58 | |
| » Starters: Marty Pattin vs Catfish Hunter | First | -- |
| Friday, September 24 |
| » Lost to Brewers (67-89), 1-0 | Oakland-Alameda County Stadium (43-34) | 98-59 | |
| » Starters: Jim Slaton vs Diego Segui | First | -- |
| Saturday, September 25 |
| » Lost to Brewers (68-89), 8-6 | Oakland-Alameda County Stadium (43-35) | 98-60 | Lost 2 |
| » Starters: Bill Parsons vs Chuck Dobson | First | -- |
| Sunday, September 26 |
| » Defeated Brewers (68-90), 7-0 | Oakland-Alameda County Stadium (44-35) | 99-60 | |
| » Starters: Skip Lockwood vs Vida Blue | First | -- |
| Tuesday, September 28 |
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