| Friday, January 23 |
| Former Senator Pep Conroy dies in Chicago, IL at the age of 72. |
| Monday, April 6 |
| » Lost to Tigers (1-0), 5-0 | Robert F. Kennedy Stadium (0-1) | 0-1 | |
| » Starters: Mickey Lolich vs Dick Bosman | Third | 1 out |
| » Major-league debuts: Dick Such (Senators) |
| Tuesday, April 7 |
| » Defeated Tigers (1-1), 14-4 | Robert F. Kennedy Stadium (1-1) | 1-1 | |
| » Starters: Earl Wilson vs Casey Cox | Second | ½ out |
| » Major-league debuts: Elliott Maddox (Tigers) |
| Wednesday, April 8 |
| » Lost to Tigers (2-1), 3-0 | Robert F. Kennedy Stadium (1-2) | 1-2 | |
| » Starters: Joe Niekro vs George Brunet | Fourth | 1½ out |
| Friday, April 10 |
| » Lost to Red Sox (2-1), 4-1 | Robert F. Kennedy Stadium (1-3) | 1-3 | Lost 2 |
| » Starters: Jim Lonborg vs Joe Coleman | Fifth | 3 out |
| Saturday, April 11 |
| » Defeated Red Sox (2-2), 4-3 | Robert F. Kennedy Stadium (2-3) | 2-3 | |
| » Starters: Sonny Siebert vs Dick Bosman | Third | 3 out |
| Sunday, April 12 |
| » Defeated Red Sox (2-3), 6-5 | Robert F. Kennedy Stadium (3-3) | 3-3 | Won 2 |
| » Starters: Gary Peters vs Casey Cox | Second | 2 out |
| Former Senator Red Shannon dies in Jersey City, NJ at the age of 74. |
| Monday, April 13 |
| » Major-league debuts: Jim Johnson (Giants) |
| Thursday, April 16 |
| » Defeated Orioles (5-2), 4-2 | Memorial Stadium (1-0) | 4-3 | Won 3 |
| » Starters: Joe Coleman vs Jim Palmer | Third | 1 out |
| Saturday, April 18 |
| » Lost to Indians (3-6), 9-4 | Cleveland Stadium (0-1) | 4-4 | |
| » Starters: Dick Bosman vs Sam McDowell | Third | 2 out |
| Monday, April 20 |
| » Lost to Yankees (5-8), 11-2 | Robert F. Kennedy Stadium (3-4) | 4-5 | Lost 2 |
| » Starters: Stan Bahnsen vs George Brunet | Fourth | 2½ out |
| Tuesday, April 21 |
| » Defeated Yankees (5-9), 7-5 | Robert F. Kennedy Stadium (4-4) | 5-5 | |
| » Starters: Mel Stottlemyre vs Casey Cox | Third | 2½ out |
| Wednesday, April 22 |
| » Defeated Yankees (5-10), 2-1 | Robert F. Kennedy Stadium (5-4) | 6-5 | Won 2 |
| » Starters: Fritz Peterson vs Joe Coleman | Third | 2½ out |
| Thursday, April 23 |
| » Lost to Yankees (6-10), 11-6 | Robert F. Kennedy Stadium (5-5) | 6-6 | |
| » Starters: Bill Burbach vs Jim Shellenback | Third | 3 out |
| Friday, April 24 |
| » Defeated Angels (10-5), 5-3 | Robert F. Kennedy Stadium (6-5) | 7-6 | |
| » Starters: Andy Messersmith vs Dick Bosman | Third | 3 out |
| Saturday, April 25 |
| » Lost to Angels (11-5), 5-3 | Robert F. Kennedy Stadium (6-6) | 7-7 | |
| » Starters: Rudy May vs George Brunet | Third | 3 out |
| Sunday, April 26 |
| » Lost to Angels (12-5), 3-2 | Robert F. Kennedy Stadium (6-7) | 7-8 | Lost 2 |
| » Starters: Tom Murphy vs Casey Cox | Third | 3½ out |
| Monday, April 27 |
| » Defeated Brewers (5-12), 6-5 | Robert F. Kennedy Stadium (7-7) | 8-8 | |
| » Starters: Marty Pattin vs Joe Coleman | Third | 3 out |
| Tuesday, April 28 |
| » Defeated Brewers (5-13), 9-6 | Robert F. Kennedy Stadium (8-7) | 9-8 | Won 2 |
| » Starters: George Lauzerique vs Jim Shellenback | Third | 3 out |
| Wednesday, April 29 |
| » Defeated Brewers (5-14), 4-0 | Robert F. Kennedy Stadium (9-7) | 10-8 | Won 3 |
| » Starters: Lew Krausse vs Dick Bosman | Third | 3 out |
| Thursday, April 30 |
| » Defeated Brewers (5-15), 12-2 | Robert F. Kennedy Stadium (10-7) | 11-8 | Won 4 |
| » Starters: Bobby Bolin vs George Brunet | Third | 2 out |
| Former Senator Chick Gagnon dies in Wilmington, DE at the age of 73. |
| Friday, May 1 |
| » Lost to Athletics (9-12), 12-5 | Robert F. Kennedy Stadium (10-8) | 11-9 | |
| » Starters: Catfish Hunter vs Casey Cox | Fourth | 3 out |
| Saturday, May 2 |
| » Lost to Athletics (10-12), 6-3 | Robert F. Kennedy Stadium (10-9) | 11-10 | Lost 2 |
| » Starters: Al Downing vs Joe Coleman | Fourth | 3 out |
| Sunday, May 3 |
| » Lost to Athletics (11-12), 3-1 | Robert F. Kennedy Stadium (10-10) | 11-11 | Lost 3 |
| » Starters: Blue Moon Odom vs Dick Bosman | Fourth | 2½ out |
| » Defeated Athletics (11-13), 6-4 | Robert F. Kennedy Stadium (11-10) | 12-11 | |
| » Starters: Chuck Dobson vs Jim Shellenback | Fourth | 2½ out |
| Tuesday, May 5 |
| » Defeated Angels (14-9), 6-1 | Anaheim Stadium (1-0) | 13-11 | Won 2 |
| » Starters: George Brunet vs Andy Messersmith | Third | 2½ out |
| Wednesday, May 6 |
| » Lost to Angels (15-9), 4-2 | Anaheim Stadium (1-1) | 13-12 | |
| » Starters: Casey Cox vs Rudy May | Fourth | 3½ out |
| Thursday, May 7 |
| » Lost to Angels (16-9), 8-0 | Anaheim Stadium (1-2) | 13-13 | Lost 2 |
| » Starters: Joe Coleman vs Tom Murphy | Fifth | 4½ out |
| Saturday, May 9 |
| » Lost to Brewers (8-20), 3-2 | County Stadium (0-1) | 13-14 | Lost 3 |
| » Starters: Dick Bosman vs John Morris | Fifth | 6 out |
| Sunday, May 10 |
| » Lost to Brewers (9-20), 6-5 | County Stadium (0-2) | 13-15 | Lost 4 |
| » Starters: George Brunet vs Gene Brabender | Fifth | 8 out |
| » Lost to Brewers (10-20), 7-6 | County Stadium (0-3) | 13-16 | Lost 5 |
| » Starters: Casey Cox vs Skip Lockwood | Fifth | 8 out |
| Tuesday, May 12 |
| » Lost to Athletics (15-16), 5-3 | Oakland-Alameda County Stadium (0-1) | 13-17 | Lost 6 |
| » Starters: Joe Coleman vs Chuck Dobson | Fifth | 9 out |
| Wednesday, May 13 |
| » Lost to Athletics (16-16), 8-1 | Oakland-Alameda County Stadium (0-2) | 13-18 | Lost 7 |
| » Starters: Jim Shellenback vs Blue Moon Odom | Fifth | 9 out |
| Friday, May 15 |
| » Lost to Orioles (23-9), 4-3 | Robert F. Kennedy Stadium (11-11) | 13-19 | Lost 8 |
| » Starters: Tom Phoebus vs Dick Bosman | Fifth | 10 out |
| Saturday, May 16 |
| » Lost to Orioles (24-9), 4-3 | Robert F. Kennedy Stadium (11-12) | 13-20 | Lost 9 |
| » Starters: Dave McNally vs Casey Cox | Fifth | 11 out |
| Former Senator Dutch Ruether dies in Phoenix, AZ at the age of 77. |
| Monday, May 18 |
| » Defeated Indians (11-19), 7-3 | Robert F. Kennedy Stadium (12-12) | 14-20 | |
| » Starters: Rich Hand vs George Brunet | Fifth | 10 out |
| Tuesday, May 19 |
| » Defeated Indians (11-20), 3-1 | Robert F. Kennedy Stadium (13-12) | 15-20 | Won 2 |
| » Starters: Barry Moore vs Joe Coleman | Fifth | 10 out |
| » Major-league debuts: Vince Colbert (Indians) |
| Wednesday, May 20 |
| » Defeated Yankees (20-18), 2-0 | Yankee Stadium (1-0) | 16-20 | Won 3 |
| » Starters: Dick Bosman vs Stan Bahnsen | Fifth | 9 out |
| Thursday, May 21 |
| » Lost to Yankees (21-18), 2-0 | Yankee Stadium (1-1) | 16-21 | |
| » Starters: Dick Such vs Mel Stottlemyre | Fifth | 9½ out |
| Friday, May 22 |
| » Lost to Tigers (18-18), 3-2 | Tiger Stadium (0-1) | 16-22 | Lost 2 |
| » Starters: Jim Hannan vs Joe Niekro | Fifth | 10½ out |
| Saturday, May 23 |
| » Defeated Tigers (18-19), 6-5 | Tiger Stadium (1-1) | 17-22 | |
| » Starters: George Brunet vs Mike Kilkenny | Fourth | 10½ out |
| Sunday, May 24 |
| » Defeated Tigers (18-20), 6-4 | Tiger Stadium (2-1) | 18-22 | Won 2 |
| » Starters: Joe Coleman vs Mickey Lolich | Fourth | 10 out |
| Monday, May 25 |
| » Lost to Red Sox (18-22), 5-3 | Fenway Park (0-1) | 18-23 | |
| » Starters: Dick Bosman vs Bill Lee | Fifth | 11 out |
| Tuesday, May 26 |
| » Defeated Red Sox (18-23), 7-5 | Fenway Park (1-1) | 19-23 | |
| » Starters: Joe Grzenda vs Gary Peters | Fourth | 11 out |
| Wednesday, May 27 |
| » Defeated Red Sox (18-24), 7-5 | Fenway Park (2-1) | 20-23 | Won 2 |
| » Starters: Jim Hannan vs Ray Culp | Fourth | 11 out |
| Friday, May 29 |
| » Defeated Royals (18-26), 5-4 | Robert F. Kennedy Stadium (14-12) | 21-23 | Won 3 |
| » Starters: Jim Rooker vs Joe Coleman | Fourth | 11 out |
| Saturday, May 30 |
| » Defeated Royals (18-27), 3-2 | Robert F. Kennedy Stadium (15-12) | 22-23 | Won 4 |
| » Starters: Bill Butler vs Dick Bosman | Third | 10 out |
| Sunday, May 31 |
| » Lost to Royals (19-27), 6-5 | Robert F. Kennedy Stadium (15-13) | 22-24 | |
| » Starters: Dave Morehead vs Casey Cox | Third | 10 out |
| Tuesday, June 2 |
| » Defeated White Sox (18-30), 4-3 | Robert F. Kennedy Stadium (16-13) | 23-24 | |
| » Starters: Joe Horlen vs George Brunet | Third | 10 out |
| Wednesday, June 3 |
| » Defeated White Sox (18-31), 5-4 | Robert F. Kennedy Stadium (17-13) | 24-24 | Won 2 |
| » Starters: Tommy John vs Joe Coleman | Third | 9 out |
| Thursday, June 4 |
| » Lost to White Sox (19-31), 7-3 | Robert F. Kennedy Stadium (17-14) | 24-25 | |
| » Starters: Jerry Crider vs Dick Bosman | Third | 9 out |
| Friday, June 5 |
| » Lost to Twins (32-15), 2-1 | Robert F. Kennedy Stadium (17-15) | 24-26 | Lost 2 |
| » Starters: Bert Blyleven vs Casey Cox | Third | 10 out |
| » Major-league debuts: Bert Blyleven (Twins) |
| Saturday, June 6 |
| » Lost to Twins (33-15), 4-2 | Robert F. Kennedy Stadium (17-16) | 24-27 | Lost 3 |
| » Starters: Jim Perry vs Jim Hannan | Fifth | 10 out |
| Sunday, June 7 |
| » Lost to Twins (34-15), 10-9 | Robert F. Kennedy Stadium (17-17) | 24-28 | Lost 4 |
| » Starters: Dave Boswell vs George Brunet | Fifth | 11 out |
| Tuesday, June 9 |
| » Lost to Royals (20-33), 8-1 | Municipal Stadium (0-1) | 24-29 | Lost 5 |
| » Starters: Casey Cox vs Dick Drago | Fourth | 11 out |
| Wednesday, June 10 |
| » Defeated Royals (20-34), 8-1 | Municipal Stadium (1-1) | 25-29 | |
| » Starters: Joe Coleman vs Jim Rooker | Fourth | 11 out |
| Friday, June 12 |
| » Lost to White Sox (22-35), 6-0 | Comiskey Park I (0-1) | 25-30 | |
| » Starters: George Brunet vs Tommy John | Fifth | 11½ out |
| Saturday, June 13 |
| » Defeated White Sox (22-36), 12-7 | Comiskey Park I (1-1) | 26-30 | |
| » Starters: Joe Grzenda vs Jerry Janeski | Fifth | 10½ out |
| Sunday, June 14 |
| » Defeated White Sox (22-37), 8-4 | Comiskey Park I (2-1) | 27-30 | Won 2 |
| » Starters: Dick Bosman vs Joe Horlen | Fifth | 10 out |
| » Defeated White Sox (22-38), 5-3 | Comiskey Park I (3-1) | 28-30 | Won 3 |
| » Starters: Casey Cox vs Jerry Crider | Fifth | 10 out |
| Monday, June 15 |
| » Lost to Twins (37-18), 5-3 | Metropolitan Stadium (0-1) | 28-31 | |
| » Starters: Joe Coleman vs Dave Boswell | Fifth | 10 out |
| Tuesday, June 16 |
| » Lost to Twins (38-18), 7-3 | Metropolitan Stadium (0-2) | 28-32 | Lost 2 |
| » Starters: Joe Grzenda vs Jim Perry | Fifth | 10½ out |
| Wednesday, June 17 |
| » Defeated Twins (38-19), 3-1 | Metropolitan Stadium (1-2) | 29-32 | |
| » Starters: George Brunet vs Jim Kaat | Fifth | 9½ out |
| Thursday, June 18 |
| » Lost to Indians (27-32), 6-3 | Cleveland Stadium (0-2) | 29-33 | |
| » Starters: Jim Hannan vs Mike Paul | Fifth | 10 out |
| Friday, June 19 |
| » Lost to Orioles (40-23), 12-10 | Memorial Stadium (1-1) | 29-34 | Lost 2 |
| » Starters: Dick Bosman vs Jim Palmer | Sixth | 12 out |
| » Lost to Orioles (41-23), 3-2 | Memorial Stadium (1-2) | 29-35 | Lost 3 |
| » Starters: Casey Cox vs Jim Hardin | Sixth | 12 out |
| Saturday, June 20 |
| » Lost to Orioles (42-23), 5-4 | Memorial Stadium (1-3) | 29-36 | Lost 4 |
| » Starters: Joe Coleman vs Mike Cuellar | Sixth | 13 out |
| Sunday, June 21 |
| » Lost to Orioles (43-23), 4-2 | Memorial Stadium (1-4) | 29-37 | Lost 5 |
| » Starters: Dick Such vs Dave McNally | Sixth | 14 out |
| Tuesday, June 23 |
| » Defeated Tigers (33-31), 6-2 | Robert F. Kennedy Stadium (18-17) | 30-37 | |
| » Starters: Mickey Lolich vs George Brunet | Sixth | 13½ out |
| Wednesday, June 24 |
| » Lost to Tigers (34-31), 3-2 | Robert F. Kennedy Stadium (18-18) | 30-38 | |
| » Starters: Earl Wilson vs Casey Cox | Sixth | 13½ out |
| Thursday, June 25 |
| » Lost to Tigers (35-31), 2-1 | Robert F. Kennedy Stadium (18-19) | 30-39 | Lost 2 |
| » Starters: Les Cain vs Dick Bosman | Sixth | 14½ out |
| Friday, June 26 |
| » Lost to Orioles (46-25), 12-2 | Robert F. Kennedy Stadium (18-20) | 30-40 | Lost 3 |
| » Starters: Dave McNally vs Joe Coleman | Sixth | 15½ out |
| Saturday, June 27 |
| » Defeated Orioles (46-26), 5-3 | Robert F. Kennedy Stadium (19-20) | 31-40 | |
| » Starters: Jim Palmer vs Dick Such | Sixth | 14½ out |
| Sunday, June 28 |
| » Defeated Orioles (46-27), 4-3 | Robert F. Kennedy Stadium (20-20) | 32-40 | Won 2 |
| » Starters: Jim Hardin vs George Brunet | Sixth | 13½ out |
| Monday, June 29 |
| » Defeated Orioles (46-28), 5-3 | Robert F. Kennedy Stadium (21-20) | 33-40 | Won 3 |
| » Starters: Mike Cuellar vs Casey Cox | Sixth | 12½ out |
| » Major-league debuts: Bobby Grich (Orioles) |
| Tuesday, June 30 |
| » Defeated Red Sox (34-36), 3-1 | Fenway Park (3-1) | 34-40 | Won 4 |
| » Starters: Dick Bosman vs Sonny Siebert | Fifth | 12½ out |
| Wednesday, July 1 |
| » Lost to Red Sox (35-36), 6-5 | Fenway Park (3-2) | 34-41 | |
| » Starters: Joe Coleman vs Mike Nagy | Fifth | 13½ out |
| Thursday, July 2 |
| » Lost to Red Sox (36-36), 5-0 | Fenway Park (3-3) | 34-42 | Lost 2 |
| » Starters: Dick Such vs Gary Peters | Sixth | 13½ out |
| » Major-league debuts: Jackie Brown (Senators) |
| Friday, July 3 |
| » Defeated Yankees (43-33), 4-3 | Yankee Stadium (2-1) | 35-42 | |
| » Starters: George Brunet vs Stan Bahnsen | Fifth | 13½ out |
| Saturday, July 4 |
| » Lost to Yankees (44-33), 4-2 | Yankee Stadium (2-2) | 35-43 | |
| » Starters: Casey Cox vs John Cumberland | Fifth | 13½ out |
| Sunday, July 5 |
| » Defeated Yankees (44-34), 7-3 | Yankee Stadium (3-2) | 36-43 | |
| » Starters: Dick Bosman vs Fritz Peterson | Fifth | 13 out |
| » Defeated Yankees (44-35), 7-3 | Yankee Stadium (4-2) | 37-43 | Won 2 |
| » Starters: Jim Shellenback vs Gary Waslewski | Fifth | 13 out |
| » Major-league debuts: Bobby Mitchell (Yankees) Tom Grieve (Senators) |
| Monday, July 6 |
| » Lost to Indians (34-44), 6-4 | Cleveland Stadium (0-3) | 37-44 | |
| » Starters: Joe Coleman vs Sam McDowell | Fifth | 13½ out |
| Tuesday, July 7 |
| » Lost to Indians (35-44), 7-3 | Cleveland Stadium (0-4) | 37-45 | Lost 2 |
| » Starters: Jim Hannan vs Dick Ellsworth | Sixth | 15 out |
| » Lost to Indians (36-44), 7-5 | Cleveland Stadium (0-5) | 37-46 | Lost 3 |
| » Starters: Dick Such vs Mike Paul | Sixth | 15 out |
| Wednesday, July 8 |
| » Lost to Indians (37-44), 6-5 | Cleveland Stadium (0-6) | 37-47 | Lost 4 |
| » Starters: George Brunet vs Steve Dunning | Sixth | 16 out |
| Thursday, July 9 |
| » Defeated Indians (37-45), 9-3 | Cleveland Stadium (1-6) | 38-47 | |
| » Starters: Casey Cox vs Rick Austin | Sixth | 15 out |
| Friday, July 10 |
| » Defeated Yankees (45-38), 2-1 | Robert F. Kennedy Stadium (22-20) | 39-47 | Won 2 |
| » Starters: Steve Kline vs Dick Bosman | Fifth | 14 out |
| » Major-league debuts: Steve Kline (Yankees) |
| Saturday, July 11 |
| » Lost to Yankees (46-38), 3-1 | Robert F. Kennedy Stadium (22-21) | 39-48 | |
| » Starters: Stan Bahnsen vs Jim Shellenback | Sixth | 15 out |
| Sunday, July 12 |
| » Defeated Yankees (46-39), 7-3 | Robert F. Kennedy Stadium (23-21) | 40-48 | |
| » Starters: Mel Stottlemyre vs Jim Hannan | Fifth | 14½ out |
| Thursday, July 16 |
| » Lost to Angels (52-35), 3-2 | Robert F. Kennedy Stadium (23-22) | 40-49 | |
| » Starters: Andy Messersmith vs Dick Bosman | Fifth | 15½ out |
| Friday, July 17 |
| » Lost to Angels (53-35), 10-0 | Robert F. Kennedy Stadium (23-23) | 40-50 | Lost 2 |
| » Starters: Clyde Wright vs Casey Cox | Sixth | 15½ out |
| Saturday, July 18 |
| » Defeated Angels (53-36), 4-0 | Robert F. Kennedy Stadium (24-23) | 41-50 | |
| » Starters: Tom Bradley vs George Brunet | Sixth | 14½ out |
| Sunday, July 19 |
| » Defeated Brewers (33-60), 4-3 | Robert F. Kennedy Stadium (25-23) | 42-50 | Won 2 |
| » Starters: Marty Pattin vs Jim Shellenback | Sixth | 14 out |
| Monday, July 20 |
| » Defeated Brewers (33-61), 2-0 | Robert F. Kennedy Stadium (26-23) | 43-50 | Won 3 |
| » Starters: Al Downing vs Jim Hannan | Sixth | 14 out |
| » Major-league debuts: Jeff Burroughs (Senators) |
| Tuesday, July 21 |
| » Lost to Athletics (50-44), 4-0 | Robert F. Kennedy Stadium (26-24) | 43-51 | |
| » Starters: Diego Segui vs Dick Bosman | Sixth | 15 out |
| Wednesday, July 22 |
| » Lost to Athletics (51-44), 4-3 | Robert F. Kennedy Stadium (26-25) | 43-52 | Lost 2 |
| » Starters: Catfish Hunter vs Casey Cox | Sixth | 16 out |
| Friday, July 24 |
| » Defeated Angels (57-40), 9-8 | Anaheim Stadium (2-2) | 44-52 | |
| » Starters: George Brunet vs Andy Messersmith | Sixth | 15½ out |
| Saturday, July 25 |
| » Defeated Angels (57-41), 5-0 | Anaheim Stadium (3-2) | 45-52 | Won 2 |
| » Starters: Jim Shellenback vs Clyde Wright | Fifth | 15½ out |
| Sunday, July 26 |
| » Lost to Angels (58-41), 11-10 | Anaheim Stadium (3-3) | 45-53 | |
| » Starters: Casey Cox vs Tom Murphy | Sixth | 16½ out |
| Tuesday, July 28 |
| » Lost to Brewers (37-63), 5-1 | County Stadium (0-4) | 45-54 | Lost 2 |
| » Starters: Jim Hannan vs Al Downing | Sixth | 17 out |
| Wednesday, July 29 |
| » Defeated Brewers (37-64), 4-2 | County Stadium (1-4) | 46-54 | |
| » Starters: Dick Bosman vs Lew Krausse | Sixth | 16 out |
| Thursday, July 30 |
| » Lost to Brewers (38-64), 6-2 | County Stadium (1-5) | 46-55 | |
| » Starters: George Brunet vs Marty Pattin | Sixth | 16½ out |
| Friday, July 31 |
| » Lost to Athletics (57-45), 5-4 | Oakland-Alameda County Stadium (0-3) | 46-56 | Lost 2 |
| » Starters: Jim Shellenback vs Rollie Fingers | Sixth | 17½ out |
| Saturday, August 1 |
| » Lost to Athletics (58-45), 5-0 | Oakland-Alameda County Stadium (0-4) | 46-57 | Lost 3 |
| » Starters: Casey Cox vs Chuck Dobson | Fifth | 18½ out |
| Sunday, August 2 |
| » Defeated Athletics (58-46), 6-2 | Oakland-Alameda County Stadium (1-4) | 47-57 | |
| » Starters: Jim Hannan vs Diego Segui | Fifth | 19 out |
| » Lost to Athletics (59-46), 1-0 | Oakland-Alameda County Stadium (1-5) | 47-58 | |
| » Starters: Joe Coleman vs Rollie Fingers | Fifth | 19 out |
| Monday, August 3 |
| » Defeated Tigers (57-48), 4-0 | Tiger Stadium (3-1) | 48-58 | |
| » Starters: Dick Bosman vs Mike Kilkenny | Sixth | 18½ out |
| Tuesday, August 4 |
| » Defeated Tigers (57-49), 4-1 | Tiger Stadium (4-1) | 49-58 | Won 2 |
| » Starters: George Brunet vs Denny McLain | Sixth | 18½ out |
| Wednesday, August 5 |
| » Lost to Tigers (58-49), 3-1 | Tiger Stadium (4-2) | 49-59 | |
| » Starters: Jim Shellenback vs Mickey Lolich | Sixth | 19½ out |
| Thursday, August 6 |
| » Defeated Red Sox (53-53), 5-2 | Robert F. Kennedy Stadium (27-25) | 50-59 | |
| » Starters: Gary Peters vs Casey Cox | Sixth | 19 out |
| Friday, August 7 |
| » Lost to Red Sox (54-53), 3-1 | Robert F. Kennedy Stadium (27-26) | 50-60 | |
| » Starters: Cal Koonce vs Jim Hannan | Sixth | 19 out |
| Saturday, August 8 |
| » Lost to Indians (55-57), 4-2 | Robert F. Kennedy Stadium (27-27) | 50-61 | Lost 2 |
| » Starters: Steve Hargan vs Dick Bosman | Sixth | 20 out |
| Sunday, August 9 |
| » Defeated Indians (55-58), 7-3 | Robert F. Kennedy Stadium (28-27) | 51-61 | |
| » Starters: Sam McDowell vs Joe Coleman | Sixth | 20 out |
| » Lost to Indians (56-58), 6-3 | Robert F. Kennedy Stadium (28-28) | 51-62 | |
| » Starters: Rick Austin vs Jackie Brown | Sixth | 20 out |
| Tuesday, August 11 |
| » Defeated Twins (69-42), 3-2 | Robert F. Kennedy Stadium (29-28) | 52-62 | |
| » Starters: Jim Perry vs Casey Cox | Sixth | 20 out |
| Wednesday, August 12 |
| » Defeated Twins (69-43), 5-3 | Robert F. Kennedy Stadium (30-28) | 53-62 | Won 2 |
| » Starters: Luis Tiant vs Jim Hannan | Sixth | 20 out |
| Thursday, August 13 |
| » Defeated Twins (69-44), 1-0 | Robert F. Kennedy Stadium (31-28) | 54-62 | Won 3 |
| » Starters: Jim Kaat vs Dick Bosman | Sixth | 19 out |
| Friday, August 14 |
| » Defeated White Sox (43-77), 6-5 | Robert F. Kennedy Stadium (32-28) | 55-62 | Won 4 |
| » Starters: Tommy John vs Joe Coleman | Sixth | 18 out |
| Saturday, August 15 |
| » Defeated White Sox (43-78), 4-2 | Robert F. Kennedy Stadium (33-28) | 56-62 | Won 5 |
| » Starters: Barry Moore vs Jackie Brown | Sixth | 18 out |
| Sunday, August 16 |
| » Defeated White Sox (43-79), 2-1 | Robert F. Kennedy Stadium (34-28) | 57-62 | Won 6 |
| » Starters: Jerry Janeski vs Casey Cox | Fifth | 18 out |
| Monday, August 17 |
| » Defeated Royals (44-76), 7-0 | Robert F. Kennedy Stadium (35-28) | 58-62 | Won 7 |
| » Starters: Bob Johnson vs Jim Hannan | Fifth | 18 out |
| Tuesday, August 18 |
| » Lost to Royals (45-76), 12-8 | Robert F. Kennedy Stadium (35-29) | 58-63 | |
| » Starters: Al Fitzmorris vs Dick Bosman | Fifth | 19 out |
| Wednesday, August 19 |
| » Lost to Royals (46-76), 2-1 | Robert F. Kennedy Stadium (35-30) | 58-64 | Lost 2 |
| » Starters: Dick Drago vs Joe Coleman | Fifth | 20 out |
| Friday, August 21 |
| » Lost to Twins (73-48), 4-3 | Metropolitan Stadium (1-3) | 58-65 | Lost 3 |
| » Starters: Casey Cox vs Bert Blyleven | Sixth | 21 out |
| Saturday, August 22 |
| » Defeated Twins (73-49), 5-4 | Metropolitan Stadium (2-3) | 59-65 | |
| » Starters: Jim Hannan vs Jim Kaat | Sixth | 20 out |
| Sunday, August 23 |
| » Defeated Twins (73-50), 11-1 | Metropolitan Stadium (3-3) | 60-65 | Won 2 |
| » Starters: Dick Bosman vs Jim Perry | Sixth | 20 out |
| Tuesday, August 25 |
| » Lost to White Sox (47-83), 4-3 | Comiskey Park I (3-2) | 60-66 | |
| » Starters: Joe Coleman vs Barry Moore | Sixth | 21 out |
| Wednesday, August 26 |
| » Lost to White Sox (48-83), 3-1 | Comiskey Park I (3-3) | 60-67 | Lost 2 |
| » Starters: Casey Cox vs Jerry Janeski | Sixth | 22 out |
| Friday, August 28 |
| » Defeated Royals (49-80), 2-1 | Municipal Stadium (2-1) | 61-67 | |
| » Starters: Dick Bosman vs Bob Johnson | Sixth | 22½ out |
| » Lost to Royals (50-80), 3-1 | Municipal Stadium (2-2) | 61-68 | |
| » Starters: Jim Hannan vs Jim Rooker | Sixth | 22½ out |
| Saturday, August 29 |
| » Defeated Royals (50-81), 11-4 | Municipal Stadium (3-2) | 62-68 | |
| » Starters: Jim Shellenback vs Al Fitzmorris | Sixth | 22½ out |
| Sunday, August 30 |
| » Lost to Royals (51-81), 4-3 | Municipal Stadium (3-3) | 62-69 | |
| » Starters: Joe Coleman vs Dick Drago | Sixth | 22½ out |
| Monday, August 31 |
| » Defeated Indians (64-69), 5-4 | Robert F. Kennedy Stadium (36-30) | 63-69 | |
| » Starters: Steve Dunning vs Casey Cox | Sixth | 22½ out |
| Tuesday, September 1 |
| » Lost to Indians (65-69), 4-3 | Robert F. Kennedy Stadium (36-31) | 63-70 | |
| » Starters: Mike Paul vs Jackie Brown | Sixth | 22½ out |
| Former Senator Ben Spencer dies in Finksburg, MD at the age of 81. |
| Wednesday, September 2 |
| » Defeated Indians (65-70), 4-1 | Robert F. Kennedy Stadium (37-31) | 64-70 | |
| » Starters: Sam McDowell vs Dick Bosman | Sixth | 21½ out |
| » Major-league debuts: John Lowenstein (Indians) |
| Thursday, September 3 |
| » Lost to Indians (66-70), 4-2 | Robert F. Kennedy Stadium (37-32) | 64-71 | |
| » Starters: Steve Hargan vs Jim Hannan | Sixth | 22½ out |
| » Major-league debuts: Bill Gogolewski (Senators) |
| Friday, September 4 |
| » Lost to Tigers (72-65), 6-3 | Robert F. Kennedy Stadium (37-33) | 64-72 | Lost 2 |
| » Starters: Mickey Lolich vs Joe Coleman | Sixth | 23½ out |
| Saturday, September 5 |
| » Defeated Tigers (72-66), 3-2 | Robert F. Kennedy Stadium (38-33) | 65-72 | |
| » Starters: Mike Kilkenny vs Casey Cox | Sixth | 23½ out |
| Sunday, September 6 |
| » Lost to Tigers (73-66), 8-7 | Robert F. Kennedy Stadium (38-34) | 65-73 | |
| » Starters: Les Cain vs Jackie Brown | Sixth | 23½ out |
| Monday, September 7 |
| » Lost to Yankees (80-60), 4-3 | Robert F. Kennedy Stadium (38-35) | 65-74 | Lost 2 |
| » Starters: Mike Kekich vs Dick Bosman | Sixth | 23½ out |
| Tuesday, September 8 |
| » Lost to Yankees (81-60), 7-3 | Robert F. Kennedy Stadium (38-36) | 65-75 | Lost 3 |
| » Starters: Mel Stottlemyre vs Jim Shellenback | Sixth | 24½ out |
| Wednesday, September 9 |
| » Defeated Indians (67-76), 5-4 | Cleveland Stadium (2-6) | 66-75 | |
| » Starters: Joe Coleman vs Rich Hand | Fifth | 24½ out |
| Thursday, September 10 |
| » Lost to Indians (68-76), 13-4 | Cleveland Stadium (2-7) | 66-76 | |
| » Starters: Casey Cox vs Steve Dunning | Sixth | 25½ out |
| Friday, September 11 |
| » Defeated Tigers (74-70), 4-2 | Tiger Stadium (5-2) | 67-76 | |
| » Starters: Bill Gogolewski vs Joe Niekro | Sixth | 25½ out |
| Saturday, September 12 |
| » Lost to Tigers (75-70), 6-4 | Tiger Stadium (5-3) | 67-77 | |
| » Starters: Dick Bosman vs Mickey Lolich | Fifth | 26½ out |
| Sunday, September 13 |
| » Defeated Tigers (75-71), 10-0 | Tiger Stadium (6-3) | 68-77 | |
| » Starters: Joe Coleman vs Mike Kilkenny | Fifth | 26½ out |
| Tuesday, September 15 |
| » Lost to Orioles (96-51), 6-2 | Robert F. Kennedy Stadium (38-37) | 68-78 | |
| » Starters: Dave McNally vs Casey Cox | Sixth | 27½ out |
| » Major-league debuts: Denny Riddleberger (Senators) |
| Wednesday, September 16 |
| » Defeated Orioles (96-52), 2-0 | Robert F. Kennedy Stadium (39-37) | 69-78 | |
| » Starters: Jim Palmer vs Bill Gogolewski | Sixth | 26½ out |
| Thursday, September 17 |
| » Defeated Orioles (96-53), 2-0 | Robert F. Kennedy Stadium (40-37) | 70-78 | Won 2 |
| » Starters: Mike Cuellar vs Dick Bosman | Sixth | 25½ out |
| » Major-league debuts: Johnny Oates (Orioles) |
| Saturday, September 19 |
| » Lost to Red Sox (78-73), 7-3 | Fenway Park (3-4) | 70-79 | |
| » Starters: Joe Coleman vs Ken Brett | Sixth | 26½ out |
| » Lost to Red Sox (79-73), 11-3 | Fenway Park (3-5) | 70-80 | Lost 2 |
| » Starters: Jim Hannan vs Mike Nagy | Sixth | 26½ out |
| Sunday, September 20 |
| » Lost to Red Sox (80-73), 3-1 | Fenway Park (3-6) | 70-81 | Lost 3 |
| » Starters: Jim Shellenback vs Ray Culp | Sixth | 27½ out |
| Monday, September 21 |
| » Lost to Yankees (87-67), 5-2 | Yankee Stadium (4-3) | 70-82 | Lost 4 |
| » Starters: Bill Gogolewski vs Fritz Peterson | Sixth | 28½ out |
| Tuesday, September 22 |
| » Lost to Yankees (88-67), 2-1 | Yankee Stadium (4-4) | 70-83 | Lost 5 |
| » Starters: Dick Bosman vs Mel Stottlemyre | Sixth | 29½ out |
| Wednesday, September 23 |
| » Lost to Yankees (89-67), 6-4 | Yankee Stadium (4-5) | 70-84 | Lost 6 |
| » Starters: Joe Coleman vs Rob Gardner | Sixth | 30 out |
| Thursday, September 24 |
| » Lost to Red Sox (83-74), 4-3 | Robert F. Kennedy Stadium (40-38) | 70-85 | Lost 7 |
| » Starters: Roger Moret vs Jim Hannan | Sixth | 31 out |
| Friday, September 25 |
| » Lost to Red Sox (84-74), 5-1 | Robert F. Kennedy Stadium (40-39) | 70-86 | Lost 8 |
| » Starters: Ray Culp vs Jim Shellenback | Sixth | 32 out |
| Saturday, September 26 |
| » Lost to Red Sox (85-74), 6-3 | Robert F. Kennedy Stadium (40-40) | 70-87 | Lost 9 |
| » Starters: Sonny Siebert vs Bill Gogolewski | Sixth | 33 out |
| Sunday, September 27 |
| » Lost to Red Sox (86-74), 10-1 | Robert F. Kennedy Stadium (40-41) | 70-88 | Lost 10 |
| » Starters: Gary Peters vs Dick Bosman | Sixth | 34 out |
| Tuesday, September 29 |
| » Lost to Orioles (105-54), 3-2 | Memorial |
