| Friday, March 13 |
| Future Royal Jorge Fabregas is born in Miami, FL. |
| Monday, April 6 |
| » Major-league debuts: Dick Such (Senators) |
| Tuesday, April 7 |
| » Lost to Athletics (1-0), 6-4 | Municipal Stadium (0-1) | 0-1 | |
| » Starters: Blue Moon Odom vs Wally Bunker | Second | 1 out |
| Wednesday, April 8 |
| » Defeated Athletics (1-1), 2-0 | Municipal Stadium (1-1) | 1-1 | |
| » Starters: Catfish Hunter vs Dick Drago | Third | 1 out |
| Thursday, April 9 |
| » Defeated Athletics (1-2), 3-1 | Municipal Stadium (2-1) | 2-1 | Won 2 |
| » Starters: Chuck Dobson vs Bill Butler | Second | ½ out |
| Friday, April 10 |
| » Lost to Angels (3-0), 11-7 | Municipal Stadium (2-2) | 2-2 | |
| » Starters: Clyde Wright vs Roger Nelson | Third | 1½ out |
| » Major-league debuts: Ken Wright (Royals) |
| Saturday, April 11 |
| » Lost to Angels (4-0), 6-3 | Municipal Stadium (2-3) | 2-3 | Lost 2 |
| » Starters: Andy Messersmith vs Wally Bunker | Third | 2½ out |
| Future Royal Joe Vitiello is born in Cambridge, MA. |
| Sunday, April 12 |
| » Lost to Angels (5-0), 7-5 | Municipal Stadium (2-4) | 2-4 | Lost 3 |
| » Starters: Tom Murphy vs Dick Drago | Fourth | 3½ out |
| Thursday, April 16 |
| » Defeated Brewers (3-6), 8-6 | County Stadium (1-0) | 3-4 | |
| » Starters: Bill Butler vs Lew Krausse | Fourth | 2 out |
| Friday, April 17 |
| » Defeated Angels (6-3), 7-5 | Anaheim Stadium (1-0) | 4-4 | Won 2 |
| » Starters: Dave Morehead vs Tom Murphy | Fourth | 1½ out |
| Saturday, April 18 |
| » Lost to Angels (7-3), 7-1 | Anaheim Stadium (1-1) | 4-5 | |
| » Starters: Wally Bunker vs Clyde Wright | Fourth | 2 out |
| Sunday, April 19 |
| » Defeated Angels (7-4), 4-1 | Anaheim Stadium (2-1) | 5-5 | |
| » Starters: Dick Drago vs Andy Messersmith | Third | 2 out |
| Monday, April 20 |
| » Defeated Athletics (5-7), 4-2 | Oakland-Alameda County Stadium (1-0) | 6-5 | Won 2 |
| » Starters: Bill Butler vs Blue Moon Odom | Third | 1½ out |
| Tuesday, April 21 |
| » Lost to Athletics (6-7), 4-3 | Oakland-Alameda County Stadium (1-1) | 6-6 | |
| » Starters: Dave Morehead vs Catfish Hunter | Third | 2½ out |
| Wednesday, April 22 |
| » Lost to Athletics (7-7), 2-1 | Oakland-Alameda County Stadium (1-2) | 6-7 | Lost 2 |
| » Starters: Wally Bunker vs Al Downing | Fourth | 3½ out |
| Friday, April 24 |
| » Lost to Orioles (9-5), 7-5 | Municipal Stadium (2-5) | 6-8 | Lost 3 |
| » Starters: Mike Cuellar vs Dick Drago | Fourth | 3½ out |
| Saturday, April 25 |
| » Lost to Orioles (10-5), 9-3 | Municipal Stadium (2-6) | 6-9 | Lost 4 |
| » Starters: Jim Palmer vs Bill Butler | Fourth | 4 out |
| Sunday, April 26 |
| » Lost to Orioles (11-5), 10-9 | Municipal Stadium (2-7) | 6-10 | Lost 5 |
| » Starters: Dave McNally vs Dave Morehead | Fourth | 5 out |
| Tuesday, April 28 |
| » Lost to Tigers (11-5), 8-3 | Municipal Stadium (2-8) | 6-11 | Lost 6 |
| » Starters: Joe Niekro vs Wally Bunker | Fourth | 5½ out |
| Wednesday, April 29 |
| » Lost to Tigers (12-5), 8-2 | Municipal Stadium (2-9) | 6-12 | Lost 7 |
| » Starters: Mike Kilkenny vs Dick Drago | Fourth | 6½ out |
| Thursday, April 30 |
| » Defeated Tigers (12-6), 3-2 | Municipal Stadium (3-9) | 7-12 | |
| » Starters: Mickey Lolich vs Bill Butler | Fourth | 5½ out |
| Friday, May 1 |
| » Lost to Indians (8-11), 7-5 | Municipal Stadium (3-10) | 7-13 | |
| » Starters: Dean Chance vs Dave Morehead | Fifth | 5½ out |
| Saturday, May 2 |
| » Defeated Indians (8-12), 4-3 | Municipal Stadium (4-10) | 8-13 | |
| » Starters: Sam McDowell vs Bob Johnson | Fifth | 5½ out |
| Sunday, May 3 |
| » Lost to Indians (9-12), 6-3 | Municipal Stadium (4-11) | 8-14 | |
| » Starters: Barry Moore vs Jim Rooker | Fifth | 6½ out |
| Tuesday, May 5 |
| » Lost to Orioles (15-8), 7-3 | Memorial Stadium (0-1) | 8-15 | Lost 2 |
| » Starters: Dick Drago vs Tom Phoebus | Fifth | 7½ out |
| Wednesday, May 6 |
| » Lost to Orioles (16-8), 3-1 | Memorial Stadium (0-2) | 8-16 | Lost 3 |
| » Starters: Bill Butler vs Dave McNally | Fifth | 7½ out |
| Thursday, May 7 |
| » Lost to Orioles (17-8), 7-6 | Memorial Stadium (0-3) | 8-17 | Lost 4 |
| » Starters: Dave Morehead vs Mike Cuellar | Fifth | 8½ out |
| Friday, May 8 |
| » Defeated Tigers (14-11), 9-3 | Tiger Stadium (1-0) | 9-17 | |
| » Starters: Bob Johnson vs Mike Kilkenny | Fifth | 8½ out |
| Saturday, May 9 |
| » Lost to Tigers (15-11), 7-4 | Tiger Stadium (1-1) | 9-18 | |
| » Starters: Jim Rooker vs Mickey Lolich | Fifth | 9½ out |
| Sunday, May 10 |
| » Defeated Tigers (15-12), 9-7 | Tiger Stadium (2-1) | 10-18 | |
| » Starters: Dick Drago vs Earl Wilson | Fifth | 8½ out |
| Wednesday, May 13 |
| » Defeated Indians (10-17), 1-0 | Cleveland Stadium (1-0) | 11-18 | Won 2 |
| » Starters: Bill Butler vs Barry Moore | Fifth | 9 out |
| Thursday, May 14 |
| » Lost to Twins (20-10), 5-2 | Metropolitan Stadium (0-1) | 11-19 | |
| » Starters: Dave Morehead vs Luis Tiant | Fifth | 9½ out |
| Future Royal Larry Sutton is born in West Covina, CA. |
| Friday, May 15 |
| » Lost to White Sox (14-17), 9-3 | Comiskey Park I (0-1) | 11-20 | Lost 2 |
| » Starters: Roger Nelson vs Joe Horlen | Fifth | 10½ out |
| Saturday, May 16 |
| » Lost to White Sox (15-17), 6-1 | Comiskey Park I (0-2) | 11-21 | Lost 3 |
| » Starters: Bob Johnson vs Tommy John | Fifth | 10½ out |
| Sunday, May 17 |
| » Defeated White Sox (15-18), 3-2 | Comiskey Park I (1-2) | 12-21 | |
| » Starters: Dick Drago vs Jerry Janeski | Fifth | 10 out |
| » Defeated White Sox (15-19), 8-4 | Comiskey Park I (2-2) | 13-21 | Won 2 |
| » Starters: Jim Rooker vs Bart Johnson | Fifth | 10 out |
| Monday, May 18 |
| » Lost to Twins (23-10), 7-5 | Municipal Stadium (4-12) | 13-22 | |
| » Starters: Jim Kaat vs Bill Butler | Fifth | 11 out |
| Tuesday, May 19 |
| » Lost to Twins (24-10), 5-4 | Municipal Stadium (4-13) | 13-23 | Lost 2 |
| » Starters: Luis Tiant vs Dave Morehead | Fifth | 12 out |
| Wednesday, May 20 |
| » Lost to Twins (25-10), 10-5 | Municipal Stadium (4-14) | 13-24 | Lost 3 |
| » Starters: Dave Boswell vs Bob Johnson | Sixth | 13 out |
| Friday, May 22 |
| » Defeated Brewers (13-24), 6-3 | Municipal Stadium (5-14) | 14-24 | |
| » Starters: Bobby Bolin vs Dick Drago | Fifth | 12 out |
| Saturday, May 23 |
| » Defeated Brewers (13-25), 3-1 | Municipal Stadium (6-14) | 15-24 | Won 2 |
| » Starters: Lew Krausse vs Jim Rooker | Fifth | 12 out |
| Sunday, May 24 |
| » Defeated Brewers (13-26), 6-5 | Municipal Stadium (7-14) | 16-24 | Won 3 |
| » Starters: John Morris vs Bill Butler | Fourth | 11 out |
| Monday, May 25 |
| » Defeated White Sox (16-26), 7-1 | Municipal Stadium (8-14) | 17-24 | Won 4 |
| » Starters: Jerry Crider vs Dave Morehead | Fourth | 11 out |
| Tuesday, May 26 |
| » Lost to White Sox (17-26), 3-1 | Municipal Stadium (8-15) | 17-25 | |
| » Starters: Jerry Janeski vs Bob Johnson | Fourth | 12 out |
| Wednesday, May 27 |
| » Defeated White Sox (17-27), 4-3 | Municipal Stadium (9-15) | 18-25 | |
| » Starters: Joe Horlen vs Dick Drago | Fourth | 11½ out |
| Friday, May 29 |
| » Lost to Senators (21-23), 5-4 | Robert F. Kennedy Stadium (0-1) | 18-26 | |
| » Starters: Jim Rooker vs Joe Coleman | Fourth | 12 out |
| Saturday, May 30 |
| » Lost to Senators (22-23), 3-2 | Robert F. Kennedy Stadium (0-2) | 18-27 | Lost 2 |
| » Starters: Bill Butler vs Dick Bosman | Fourth | 13 out |
| Sunday, May 31 |
| » Defeated Senators (22-24), 6-5 | Robert F. Kennedy Stadium (1-2) | 19-27 | |
| » Starters: Dave Morehead vs Casey Cox | Fourth | 13 out |
| Future Royal Dilson Torres is born in Sur Edo Aragua, Venezuela. |
| Tuesday, June 2 |
| » Lost to Yankees (27-23), 3-2 | Yankee Stadium (0-1) | 19-28 | |
| » Starters: Bob Johnson vs Fritz Peterson | Fourth | 13 out |
| Wednesday, June 3 |
| » Lost to Yankees (28-23), 5-3 | Yankee Stadium (0-2) | 19-29 | Lost 2 |
| » Starters: Dick Drago vs Mike Kekich | Fourth | 13½ out |
| Thursday, June 4 |
| » Lost to Yankees (29-23), 2-1 | Yankee Stadium (0-3) | 19-30 | Lost 3 |
| » Starters: Jim Rooker vs Stan Bahnsen | Fourth | 13½ out |
| Friday, June 5 |
| » Lost to Red Sox (23-25), 4-2 | Fenway Park (0-1) | 19-31 | Lost 4 |
| » Starters: Bill Butler vs Mike Nagy | Fourth | 14½ out |
| Sunday, June 7 |
| » Lost to Red Sox (24-25), 7-4 | Fenway Park (0-2) | 19-32 | Lost 5 |
| » Starters: Dave Morehead vs Ray Culp | Fifth | 16½ out |
| » Lost to Red Sox (25-25), 5-2 | Fenway Park (0-3) | 19-33 | Lost 6 |
| » Starters: Bob Johnson vs Gary Peters | Fifth | 16½ out |
| Tuesday, June 9 |
| » Defeated Senators (24-29), 8-1 | Municipal Stadium (10-15) | 20-33 | |
| » Manager: Bob Lemon |
| » Starters: Casey Cox vs Dick Drago | Fifth | 15½ out |
| Wednesday, June 10 |
| » Lost to Senators (25-29), 8-1 | Municipal Stadium (10-16) | 20-34 | |
| » Starters: Joe Coleman vs Jim Rooker | Fifth | 15½ out |
| Friday, June 12 |
| » Lost to Yankees (34-24), 5-0 | Municipal Stadium (10-17) | 20-35 | Lost 2 |
| » Starters: Fritz Peterson vs Dave Morehead | Fifth | 16½ out |
| Saturday, June 13 |
| » Lost to Yankees (35-24), 9-4 | Municipal Stadium (10-18) | 20-36 | Lost 3 |
| » Starters: Mike Kekich vs Bob Johnson | Fifth | 16½ out |
| Sunday, June 14 |
| » Lost to Yankees (36-24), 3-2 | Municipal Stadium (10-19) | 20-37 | Lost 4 |
| » Starters: Stan Bahnsen vs Dick Drago | Fifth | 17½ out |
| Monday, June 15 |
| » Defeated Red Sox (27-29), 7-6 | Municipal Stadium (11-19) | 21-37 | |
| » Starters: Mike Nagy vs Jim Rooker | Fifth | 17½ out |
| Tuesday, June 16 |
| » Lost to Red Sox (28-29), 7-5 | Municipal Stadium (11-20) | 21-38 | |
| » Starters: Gary Peters vs Bill Butler | Fifth | 18½ out |
| Wednesday, June 17 |
| » Lost to Red Sox (29-29), 3-1 | Municipal Stadium (11-21) | 21-39 | Lost 2 |
| » Starters: Ken Brett vs Dave Morehead | Fifth | 18½ out |
| Friday, June 19 |
| » Defeated Twins (38-20), 5-1 | Municipal Stadium (12-21) | 22-39 | |
| » Starters: Bert Blyleven vs Dick Drago | Fifth | 17½ out |
| Saturday, June 20 |
| » Defeated Twins (38-21), 5-3 | Municipal Stadium (13-21) | 23-39 | Won 2 |
| » Starters: Dave Boswell vs Jim Rooker | Fifth | 16½ out |
| Sunday, June 21 |
| » Lost to Twins (39-21), 11-2 | Municipal Stadium (13-22) | 23-40 | |
| » Starters: Jim Perry vs Bill Butler | Fourth | 17½ out |
| Monday, June 22 |
| » Lost to Athletics (38-30), 2-1 | Oakland-Alameda County Stadium (1-3) | 23-41 | Lost 2 |
| » Starters: Dave Morehead vs Diego Segui | Fifth | 18½ out |
| Tuesday, June 23 |
| » Defeated Athletics (38-31), 7-5 | Oakland-Alameda County Stadium (2-3) | 24-41 | |
| » Starters: Dick Drago vs Chuck Dobson | Fifth | 17½ out |
| Wednesday, June 24 |
| » Lost to Athletics (39-31), 5-1 | Oakland-Alameda County Stadium (2-4) | 24-42 | |
| » Starters: Jim Rooker vs Darrell Osteen | Fourth | 18½ out |
| Friday, June 26 |
| » Lost to Angels (41-28), 5-4 | Municipal Stadium (13-23) | 24-43 | Lost 2 |
| » Starters: Rudy May vs Bill Butler | Fifth | 18 out |
| Saturday, June 27 |
| » Defeated Angels (41-29), 2-0 | Municipal Stadium (14-23) | 25-43 | |
| » Starters: Andy Messersmith vs Dave Morehead | Fourth | 18 out |
| Sunday, June 28 |
| » Lost to Angels (42-29), 2-1 | Municipal Stadium (14-24) | 25-44 | |
| » Starters: Tom Murphy vs Jim Rooker | Fourth | 18 out |
| » Defeated Angels (42-30), 13-1 | Municipal Stadium (15-24) | 26-44 | |
| » Starters: Mel Queen vs Al Fitzmorris | Fourth | 18 out |
| Monday, June 29 |
| » Lost to Twins (44-25), 5-4 | Metropolitan Stadium (0-2) | 26-45 | |
| » Starters: Dick Drago vs Jim Perry | Fourth | 19 out |
| Tuesday, June 30 |
| » Lost to Twins (45-25), 8-5 | Metropolitan Stadium (0-3) | 26-46 | Lost 2 |
| » Starters: Don O'Riley vs Jim Kaat | Fourth | 20 out |
| Wednesday, July 1 |
| » Lost to Twins (46-25), 2-1 | Metropolitan Stadium (0-4) | 26-47 | Lost 3 |
| » Starters: Jim Rooker vs Bert Blyleven | Fourth | 21 out |
| Thursday, July 2 |
| » Lost to Twins (47-25), 5-2 | Metropolitan Stadium (0-5) | 26-48 | Lost 4 |
| » Starters: Al Fitzmorris vs Tom Hall | Fourth | 22 out |
| Friday, July 3 |
| » Defeated Brewers (26-51), 5-3 | County Stadium (2-0) | 27-48 | |
| » Starters: Dick Drago vs Marty Pattin | Fourth | 21½ out |
| » Defeated Brewers (26-52), 4-3 | County Stadium (3-0) | 28-48 | Won 2 |
| » Starters: Bob Johnson vs Al Downing | Fourth | 21½ out |
| Saturday, July 4 |
| » Defeated Brewers (26-53), 8-6 | County Stadium (4-0) | 29-48 | Won 3 |
| » Starters: Don O'Riley vs Lew Krausse | Fourth | 20½ out |
| Sunday, July 5 |
| » Lost to Brewers (27-53), 2-1 | County Stadium (4-1) | 29-49 | |
| » Starters: Bill Butler vs Skip Lockwood | Fourth | 21½ out |
| Future Royal Doug Bochtler is born in West Palm Beach, FL. |
| Monday, July 6 |
| » Lost to Angels (48-32), 6-2 | Anaheim Stadium (2-2) | 29-50 | Lost 2 |
| » Starters: Jim Rooker vs Tom Murphy | Fourth | 22½ out |
| Tuesday, July 7 |
| » Defeated Angels (48-33), 4-3 | Anaheim Stadium (3-2) | 30-50 | |
| » Starters: Al Fitzmorris vs Clyde Wright | Fourth | 22½ out |
| Wednesday, July 8 |
| » Lost to Angels (49-33), 3-2 | Anaheim Stadium (3-3) | 30-51 | |
| » Starters: Dick Drago vs Tom Bradley | Fourth | 23½ out |
| Friday, July 10 |
| » Defeated White Sox (30-56), 8-6 | Municipal Stadium (16-24) | 31-51 | |
| » Starters: Jerry Janeski vs Bob Johnson | Fourth | 22½ out |
| » Defeated White Sox (30-57), 2-0 | Municipal Stadium (17-24) | 32-51 | Won 2 |
| » Starters: Bob Miller vs Jim Rooker | Fourth | 22½ out |
| Saturday, July 11 |
| » Defeated White Sox (30-58), 4-0 | Municipal Stadium (18-24) | 33-51 | Won 3 |
| » Starters: Joe Horlen vs Bill Butler | Fourth | 22½ out |
| Sunday, July 12 |
| » Lost to White Sox (31-58), 10-5 | Municipal Stadium (18-25) | 33-52 | |
| » Starters: Tommy John vs Dick Drago | Fourth | 22½ out |
| Thursday, July 16 |
| » Lost to Indians (39-48), 6-0 | Municipal Stadium (18-26) | 33-53 | Lost 2 |
| » Starters: Rich Hand vs Jim Rooker | Fourth | 22½ out |
| Friday, July 17 |
| » Lost to Indians (40-48), 6-0 | Municipal Stadium (18-27) | 33-54 | Lost 3 |
| » Starters: Steve Dunning vs Bob Johnson | Fourth | 23½ out |
| Saturday, July 18 |
| » Lost to Indians (41-48), 4-1 | Municipal Stadium (18-28) | 33-55 | Lost 4 |
| » Starters: Steve Hargan vs Bill Butler | Fourth | 24½ out |
| Sunday, July 19 |
| » Lost to Tigers (51-38), 2-0 | Municipal Stadium (18-29) | 33-56 | Lost 5 |
| » Starters: Joe Niekro vs Dick Drago | Fourth | 25 out |
| » Lost to Tigers (52-38), 6-4 | Municipal Stadium (18-30) | 33-57 | Lost 6 |
| » Starters: Mike Kilkenny vs Dave Morehead | Fourth | 25 out |
| Monday, July 20 |
| » Defeated Tigers (52-39), 3-0 | Municipal Stadium (19-30) | 34-57 | |
| » Starters: Les Cain vs Jim Rooker | Fourth | 25 out |
| Tuesday, July 21 |
| » Lost to Orioles (58-36), 2-1 | Municipal Stadium (19-31) | 34-58 | |
| » Starters: Jim Hardin vs Bob Johnson | Fourth | 25 out |
| Wednesday, July 22 |
| » Lost to Orioles (59-36), 4-3 | Municipal Stadium (19-32) | 34-59 | Lost 2 |
| » Starters: Dave McNally vs Bill Butler | Fourth | 26 out |
| Thursday, July 23 |
| » Lost to Orioles (60-36), 5-4 | Municipal Stadium (19-33) | 34-60 | Lost 3 |
| » Starters: Jim Palmer vs Dick Drago | Fourth | 27 out |
| Friday, July 24 |
| » Defeated Indians (44-51), 5-2 | Cleveland Stadium (2-0) | 35-60 | |
| » Starters: Jim Rooker vs Rich Hand | Fourth | 27½ out |
| » Lost to Indians (45-51), 9-6 | Cleveland Stadium (2-1) | 35-61 | |
| » Starters: Wally Bunker vs Dean Chance | Fourth | 27½ out |
| Saturday, July 25 |
| » Defeated Indians (45-52), 8-4 | Cleveland Stadium (3-1) | 36-61 | |
| » Starters: Bob Johnson vs Rick Austin | Fourth | 26½ out |
| Sunday, July 26 |
| » Lost to Indians (46-52), 6-5 | Cleveland Stadium (3-2) | 36-62 | |
| » Starters: Bill Butler vs Steve Dunning | Fourth | 27 out |
| » Lost to Indians (47-52), 3-0 | Cleveland Stadium (3-3) | 36-63 | Lost 2 |
| » Starters: Dave Morehead vs Steve Hargan | Fourth | 27 out |
| Tuesday, July 28 |
| » Defeated Tigers (55-44), 7-6 | Tiger Stadium (3-1) | 37-63 | |
| » Starters: Dick Drago vs Joe Niekro | Fourth | 27½ out |
| » Major-league debuts: Lerrin LaGrow (Tigers) |
| Wednesday, July 29 |
| » Lost to Tigers (56-44), 10-3 | Tiger Stadium (3-2) | 37-64 | |
| » Starters: Jim Rooker vs Les Cain | Fourth | 27½ out |
| Thursday, July 30 |
| » Defeated Tigers (56-45), 3-2 | Tiger Stadium (4-2) | 38-64 | |
| » Starters: Bob Johnson vs Mike Kilkenny | Fourth | 26½ out |
| Friday, July 31 |
| » Lost to Orioles (64-39), 3-1 | Memorial Stadium (0-4) | 38-65 | |
| » Starters: Bill Butler vs Dave McNally | Fourth | 26½ out |
| Saturday, August 1 |
| » Lost to Orioles (65-39), 9-1 | Memorial Stadium (0-5) | 38-66 | Lost 2 |
| » Starters: Dick Drago vs Jim Palmer | Fourth | 27½ out |
| Sunday, August 2 |
| » Lost to Orioles (66-39), 10-8 | Memorial Stadium (0-6) | 38-67 | Lost 3 |
| » Starters: Jim Rooker vs Mike Cuellar | Fourth | 28½ out |
| Monday, August 3 |
| » Defeated White Sox (38-71), 7-2 | Comiskey Park I (3-2) | 39-67 | |
| » Starters: Bob Johnson vs Bob Miller | Fifth | 28 out |
| Tuesday, August 4 |
| » Lost to White Sox (39-71), 2-1 | Comiskey Park I (3-3) | 39-68 | |
| » Starters: Bill Butler vs Tommy John | Fourth | 29 out |
| Wednesday, August 5 |
| » Lost to Athletics (61-47), 4-1 | Municipal Stadium (19-34) | 39-69 | Lost 2 |
| » Starters: Chuck Dobson vs Dick Drago | Fourth | 29 out |
| Thursday, August 6 |
| » Defeated Athletics (61-48), 5-3 | Municipal Stadium (20-34) | 40-69 | |
| » Starters: Diego Segui vs Jim Rooker | Third | 29 out |
| Friday, August 7 |
| » Defeated Brewers (40-72), 4-0 | Municipal Stadium (21-34) | 41-69 | Won 2 |
| » Starters: Skip Lockwood vs Bob Johnson | Fourth | 28½ out |
| » Defeated Brewers (40-73), 10-2 | Municipal Stadium (22-34) | 42-69 | Won 3 |
| » Starters: Lew Krausse vs Dave Morehead | Fourth | 28½ out |
| Future Royal Marc Pisciotta is born in Edison, NJ. |
| Saturday, August 8 |
| » Lost to Brewers (41-73), 5-3 | Municipal Stadium (22-35) | 42-70 | |
| » Starters: Marty Pattin vs Bill Butler | Fourth | 29½ out |
| Sunday, August 9 |
| » Lost to Brewers (42-73), 4-2 | Municipal Stadium (22-36) | 42-71 | Lost 2 |
| » Starters: Bobby Bolin vs Dick Drago | Fourth | 29 out |
| Wednesday, August 12 |
| » Lost to Red Sox (57-54), 7-4 | Fenway Park (0-4) | 42-72 | Lost 3 |
| » Starters: Jim Rooker vs Gary Peters | Fourth | 27½ out |
| » Defeated Red Sox (57-55), 4-3 | Fenway Park (1-4) | 43-72 | |
| » Starters: Bob Johnson vs Cal Koonce | Fourth | 27½ out |
| Thursday, August 13 |
| » Defeated Red Sox (57-56), 11-3 | Fenway Park (2-4) | 44-72 | Won 2 |
| » Starters: Al Fitzmorris vs Vicente Romo | Fourth | 26½ out |
| » Major-league debuts: John Curtis (Red Sox) |
| Friday, August 14 |
| » Lost to Yankees (64-52), 3-2 | Yankee Stadium (0-4) | 44-73 | |
| » Starters: Dick Drago vs Fritz Peterson | Fifth | 26½ out |
| Saturday, August 15 |
| » Lost to Yankees (65-52), 5-4 | Yankee Stadium (0-5) | 44-74 | Lost 2 |
| » Starters: Wally Bunker vs Mel Stottlemyre | Fifth | 26 out |
| Sunday, August 16 |
| » Lost to Yankees (66-52), 5-1 | Yankee Stadium (0-6) | 44-75 | Lost 3 |
| » Starters: Jim Rooker vs Stan Bahnsen | Fifth | 27 out |
| Monday, August 17 |
| » Lost to Senators (58-62), 7-0 | Robert F. Kennedy Stadium (1-3) | 44-76 | Lost 4 |
| » Starters: Bob Johnson vs Jim Hannan | Fifth | 27½ out |
| Tuesday, August 18 |
| » Defeated Senators (58-63), 12-8 | Robert F. Kennedy Stadium (2-3) | 45-76 | |
| » Starters: Al Fitzmorris vs Dick Bosman | Fifth | 27½ out |
| Wednesday, August 19 |
| » Defeated Senators (58-64), 2-1 | Robert F. Kennedy Stadium (3-3) | 46-76 | Won 2 |
| » Starters: Dick Drago vs Joe Coleman | Fourth | 27½ out |
| Friday, August 21 |
| » Defeated Red Sox (62-59), 2-1 | Municipal Stadium (23-36) | 47-76 | Won 3 |
| » Starters: Sonny Siebert vs Wally Bunker | Fourth | 27 out |
| Saturday, August 22 |
| » Lost to Red Sox (63-59), 8-1 | Municipal Stadium (23-37) | 47-77 | |
| » Starters: Gary Peters vs Jim Rooker | Fourth | 27 out |
| Sunday, August 23 |
| » Defeated Red Sox (63-60), 4-3 | Municipal Stadium (24-37) | 48-77 | |
| » Starters: Cal Koonce vs Bob Johnson | Fourth | 26 out |
| Monday, August 24 |
| » Defeated Yankees (69-57), 8-7 | Municipal Stadium (25-37) | 49-77 | Won 2 |
| » Starters: Mel Stottlemyre vs Al Fitzmorris | Fourth | 25½ out |
| Tuesday, August 25 |
| » Lost to Yankees (70-57), 2-1 | Municipal Stadium (25-38) | 49-78 | |
| » Starters: Steve Kline vs Dick Drago | Fourth | 25½ out |
| Wednesday, August 26 |
| » Lost to Yankees (71-57), 3-0 | Municipal Stadium (25-39) | 49-79 | Lost 2 |
| » Starters: Stan Bahnsen vs Wally Bunker | Fourth | 26½ out |
| Friday, August 28 |
| » Lost to Senators (61-67), 2-1 | Municipal Stadium (25-40) | 49-80 | Lost 3 |
| » Starters: Dick Bosman vs Bob Johnson | Fourth | 26 out |
| » Defeated Senators (61-68), 3-1 | Municipal Stadium (26-40) | 50-80 | |
| » Starters: Jim Hannan vs Jim Rooker | Fourth | 26 out |
| Saturday, August 29 |
| » Lost to Senators (62-68), 11-4 | Municipal Stadium (26-41) | 50-81 | |
| » Starters: Jim Shellenback vs Al Fitzmorris | Fourth | 27 out |
| Sunday, August 30 |
| » Defeated Senators (62-69), 4-3 | Municipal Stadium (27-41) | 51-81 | |
| » Starters: Joe Coleman vs Dick Drago | Fourth | 26 out |
| Tuesday, September 1 |
| » Defeated Angels (74-59), 4-0 | Anaheim Stadium (4-3) | 52-81 | Won 2 |
| » Starters: Wally Bunker vs Tom Murphy | Fourth | 26½ out |
| Wednesday, September 2 |
| » Lost to Angels (75-59), 3-1 | Anaheim Stadium (4-4) | 52-82 | |
| » Starters: Bob Johnson vs Clyde Wright | Fourth | 27 out |
| Thursday, September 3 |
| » Lost to Angels (76-59), 1-0 | Anaheim Stadium (4-5) | 52-83 | Lost 2 |
| » Starters: Jim Rooker vs Tom Bradley | Fourth | 27 out |
| Friday, September 4 |
| » Lost to Athletics (74-62), 5-0 | Oakland-Alameda County Stadium (2-5) | 52-84 | Lost 3 |
| » Starters: Al Fitzmorris vs Catfish Hunter | Fourth | 28 out |
| Saturday, September 5 |
| » Lost to Athletics (75-62), 8-3 | Oakland-Alameda County Stadium (2-6) | 52-85 | Lost 4 |
| » Starters: Dick Drago vs Chuck Dobson | Fourth | 29 out |
| Sunday, September 6 |
| » Lost to Athletics (76-62), 7-1 | Oakland-Alameda County Stadium (2-7) | 52-86 | Lost 5 |
| » Starters: Wally Bunker vs Blue Moon Odom | Fourth | 30 out |
| Monday, September 7 |
| » Defeated Angels (76-63), 4-1 | Municipal Stadium (28-41) | 53-86 | |
| » Starters: Tom Bradley vs Bob Johnson | Fourth | 30½ out |
| Tuesday, September 8 |
| » Defeated Angels (76-64), 12-0 | Municipal Stadium (29-41) | 54-86 | Won 2 |
| » Starters: Rudy May vs Jim Rooker | Fourth | 29½ out |
| Thursday, September 10 |
| » Defeated Brewers (53-88), 2-0 | Municipal Stadium (30-41) | 55-86 | Won 3 |
| » Starters: Skip Lockwood vs Bill Butler | Fourth | 30 out |
| » Defeated Brewers (53-89), 10-2 | Municipal Stadium (31-41) | 56-86 | Won 4 |
| » Starters: John Morris vs Dick Drago | Fourth | 30 out |
| Friday, September 11 |
| » Lost to Athletics (79-65), 3-0 | Municipal Stadium (31-42) | 56-87 | |
| » Starters: Vida Blue vs Wally Bunker | Fourth | 31 out |
| Saturday, September 12 |
| » Lost to Athletics (80-65), 3-2 | Municipal Stadium (31-43) | 56-88 | Lost 2 |
| » Starters: Diego Segui vs Bob Johnson | Fourth | 31 out |
| Sunday, September 13 |
| » Defeated Athletics (80-66), 8-7 | Municipal Stadium (32-43) | 57-88 | |
| » Starters: Chuck Dobson vs Jim Rooker | Fourth | 29½ out |
| » Defeated Athletics (80-67), 8-7 | Municipal Stadium (33-43) | 58-88 | Won 2 |
| » Starters: Catfish Hunter vs Al Fitzmorris | Fourth | 29½ out |
| Tuesday, September 15 |
| » Major-league debuts: Denny Riddleberger (Senators) |
| Thursday, September 17 |
| » Lost to Brewers (57-92), 4-3 | County Stadium (4-2) | 58-89 | |
| » Starters: Dick Drago vs Marty Pattin | Fourth | 30 out |
| Friday, September 18 |
| » Lost to Brewers (58-92), 4-3 | County Stadium (4-3) | 58-90 | Lost 2 |
| » Starters: Bill Butler vs Al Downing | Fourth | 31 out |
| Saturday, September 19 |
| » Defeated Brewers (58-93), 4-1 | County Stadium (5-3) | 59-90 | |
| » Starters: Wally Bunker vs John Morris | Fourth | 31 out |
| Sunday, September 20 |
| » Lost to Brewers (59-93), 4-3 | County Stadium (5-4) | 59-91 | |
| » Starters: Bob Johnson vs Skip Lockwood | Fourth | 32 out |
| Monday, September 21 |
| » Lost to White Sox (54-96), 8-4 | Comiskey Park I (3-4) | 59-92 | Lost 2 |
| » Starters: Jim Rooker vs Joe Horlen | Fourth | 31½ out |
| » Defeated White Sox (54-97), 8-2 | Comiskey Park I (4-4) | 60-92 | |
| » Starters: Bill Butler vs Floyd Weaver | Fourth | 31½ out |
| » Major-league debuts: Art Kusnyer (White Sox) Jim York (Royals) |
| Tuesday, September 22 |
| » Defeated White Sox (54-98), 2-1 | Comiskey Park I (5-4) | 61-92 | Won 2 |
| » Starters: Dick Drago vs Billy Wynne | Fourth | 31 out |
| » Defeated White Sox (54-99), 6-2 | Comiskey Park I (6-4) | 62-92 | Won 3 |
| » Starters: Al Fitzmorris vs Jim Magnuson | Fourth | 31 out |
| Wednesday, September 23 |
| » Lost to White Sox (55-99), 6-0 | Comiskey Park I (6-5) | 62-93 | |
| » Starters: Paul Splittorff vs Bart Johnson | Fourth | 32 out |
| » Major-league debuts: Paul Splittorff (Royals) |
| Thursday, September 24 |
| Future Royal Paul Spoljaric is born in Kelowna, BC. |
| Friday, September 25 |
| » Lost to Twins (95-61), 1-0 | Municipal Stadium (33-44) | 62-94 | Lost 2 |
| » Starters: Jim Perry vs Wally Bunker | Fourth | 33 out |
| Future Royal Ray Holbert is born in Torrance, CA. |
| Saturday, September 26 |
| » Defeated Twins (95-62), 5-0 | Municipal Stadium (34-44) | 63-94 | |
| » Starters: Bert Blyleven vs Bob Johnson | Fourth | 32 out |
| Sunday, September 27 |
| » Defeated Twins (95-63), 4-3 | Municipal Stadium (35-44) | 64-94 | Won 2 |
| » Starters: Luis Tiant vs Jim Rooker | Fourth | 31 out |
| Monday, September 28 |
| » Lost to Twins (96-63), 1-0 | Metropolitan Stadium (0-6) | 64-95 | |
| » Starters: Dick Drago vs Tom Hall | Fourth | 32 out |
| Tuesday, September 29 |
| » Defeated Twins (96-64), 14-13 | Metropolitan Stadium (1-6) | 65-95 | |
| < |
