| Friday, January 9 |
| Former Red Sox Ray Collins dies in Burlington, VT at the age of 83. |
| Wednesday, January 14 |
| Former Red Sox Johnny Murphy dies in New York, NY at the age of 62. |
| Friday, January 23 |
| Future Red Sox Alan Embree is born in The Dalles, OR. |
| Saturday, February 21 |
| Former Red Sox Tom Carey dies in Rochester, NY at the age of 64. |
| Monday, April 6 |
| » Major-league debuts: Dick Such (Senators) |
| Tuesday, April 7 |
| » Defeated Yankees (0-1), 4-3 | Yankee Stadium (1-0) | 1-0 | |
| » Starters: Gary Peters vs Mel Stottlemyre | First | -- |
| Thursday, April 9 |
| » Lost to Yankees (1-1), 4-3 | Yankee Stadium (1-1) | 1-1 | |
| » Starters: Ray Culp vs Fritz Peterson | Third | 1½ out |
| Friday, April 10 |
| » Defeated Senators (1-3), 4-1 | Robert F. Kennedy Stadium (1-0) | 2-1 | |
| » Starters: Jim Lonborg vs Joe Coleman | Second | 1½ out |
| Saturday, April 11 |
| » Lost to Senators (2-3), 4-3 | Robert F. Kennedy Stadium (1-1) | 2-2 | |
| » Starters: Sonny Siebert vs Dick Bosman | Second | 2½ out |
| Former Red Sox Joe Heving dies in Covington, KY at the age of 70. |
| Sunday, April 12 |
| » Lost to Senators (3-3), 6-5 | Robert F. Kennedy Stadium (1-2) | 2-3 | Lost 2 |
| » Starters: Gary Peters vs Casey Cox | Third | 2½ out |
| Former Red Sox Red Shannon dies in Jersey City, NJ at the age of 74. |
| Tuesday, April 14 |
| » Defeated Yankees (2-4), 8-3 | Fenway Park (1-0) | 3-3 | |
| » Starters: Fritz Peterson vs Ray Culp | Third | 2 out |
| Future Red Sox Steve Avery is born in Trenton, MI. |
| Wednesday, April 15 |
| » Defeated Yankees (2-5), 6-2 | Fenway Park (2-0) | 4-3 | Won 2 |
| » Starters: Bill Burbach vs Jim Lonborg | Second | 1½ out |
| Thursday, April 16 |
| » Defeated Yankees (2-6), 8-5 | Fenway Park (3-0) | 5-3 | Won 3 |
| » Starters: Stan Bahnsen vs Sonny Siebert | Second | ½ out |
| Friday, April 17 |
| » Lost to Tigers (6-3), 3-2 | Tiger Stadium (0-1) | 5-4 | |
| » Starters: Gary Peters vs Mickey Lolich | Fourth | 1 out |
| Saturday, April 18 |
| » Lost to Tigers (7-3), 5-1 | Tiger Stadium (0-2) | 5-5 | Lost 2 |
| » Starters: Bill Lee vs Joe Niekro | Fourth | 2 out |
| Future Red Sox Rico Brogna is born in Turners Falls, MA. |
| Monday, April 20 |
| » Lost to Orioles (8-4), 3-2 | Fenway Park (3-1) | 5-6 | Lost 3 |
| » Starters: Jim Palmer vs Ray Culp | Third | 2½ out |
| Wednesday, April 22 |
| » Defeated Orioles (8-5), 5-2 | Fenway Park (4-1) | 6-6 | |
| » Starters: Dave McNally vs Jim Lonborg | Fourth | 3 out |
| Saturday, April 25 |
| » Lost to Brewers (4-10), 10-4 | Fenway Park (4-2) | 6-7 | |
| » Starters: Lew Krausse vs Sonny Siebert | Third | 3 out |
| » Defeated Brewers (4-11), 3-0 | Fenway Park (5-2) | 7-7 | |
| » Starters: Bobby Bolin vs Gary Peters | Third | 3 out |
| Sunday, April 26 |
| » Lost to Brewers (5-11), 5-3 | Fenway Park (5-3) | 7-8 | |
| » Starters: Gene Brabender vs Ray Culp | Third | 3½ out |
| Monday, April 27 |
| » Defeated Athletics (8-9), 4-3 | Fenway Park (6-3) | 8-8 | |
| » Starters: Catfish Hunter vs Vicente Romo | Third | 3 out |
| Tuesday, April 28 |
| » Defeated Athletics (8-10), 2-1 | Fenway Park (7-3) | 9-8 | Won 2 |
| » Starters: Al Downing vs Bill Lee | Third | 3 out |
| Wednesday, April 29 |
| » Defeated Athletics (8-11), 5-3 | Fenway Park (8-3) | 10-8 | Won 3 |
| » Starters: Chuck Dobson vs Sonny Siebert | Third | 3 out |
| Thursday, April 30 |
| » Defeated Athletics (8-12), 8-7 | Fenway Park (9-3) | 11-8 | Won 4 |
| » Starters: Jim Roland vs Gary Peters | Third | 2 out |
| Friday, May 1 |
| » Defeated Angels (13-8), 8-3 | Fenway Park (10-3) | 12-8 | Won 5 |
| » Starters: Tom Murphy vs Ray Culp | Third | 2 out |
| Saturday, May 2 |
| » Lost to Angels (14-8), 8-4 | Fenway Park (10-4) | 12-9 | |
| » Starters: Clyde Wright vs Vicente Romo | Third | 2 out |
| Tuesday, May 5 |
| » Defeated Brewers (5-20), 6-0 | County Stadium (1-0) | 13-9 | |
| » Starters: Sonny Siebert vs Gene Brabender | Second | 1½ out |
| Wednesday, May 6 |
| » Lost to Brewers (6-20), 4-3 | County Stadium (1-1) | 13-10 | |
| » Starters: Gary Peters vs Bobby Bolin | Third | 2½ out |
| Thursday, May 7 |
| » Lost to Brewers (7-20), 5-1 | County Stadium (1-2) | 13-11 | Lost 2 |
| » Starters: Ray Culp vs Lew Krausse | Third | 3½ out |
| Friday, May 8 |
| » Lost to Athletics (13-15), 7-1 | Oakland-Alameda County Stadium (0-1) | 13-12 | Lost 3 |
| » Starters: Jim Lonborg vs Chuck Dobson | Third | 4½ out |
| Saturday, May 9 |
| » Defeated Athletics (13-16), 5-3 | Oakland-Alameda County Stadium (1-1) | 14-12 | |
| » Starters: Sonny Siebert vs Catfish Hunter | Third | 4½ out |
| Sunday, May 10 |
| » Lost to Athletics (14-16), 7-4 | Oakland-Alameda County Stadium (1-2) | 14-13 | |
| » Starters: Gary Peters vs Blue Moon Odom | Third | 6 out |
| Monday, May 11 |
| » Lost to Angels (19-10), 2-1 | Anaheim Stadium (0-1) | 14-14 | Lost 2 |
| » Starters: Ray Culp vs Tom Murphy | Fourth | 6½ out |
| » Major-league debuts: Dave LaRoche (Angels) |
| Tuesday, May 12 |
| » Lost to Angels (20-10), 6-5 | Anaheim Stadium (0-2) | 14-15 | Lost 3 |
| » Starters: Bill Lee vs Clyde Wright | Fourth | 7½ out |
| Wednesday, May 13 |
| » Lost to Angels (21-10), 5-3 | Anaheim Stadium (0-3) | 14-16 | Lost 4 |
| » Starters: Sonny Siebert vs Andy Messersmith | Fourth | 7½ out |
| Former Red Sox Urbane Pickering dies in Modesto, CA at the age of 71. |
| Friday, May 15 |
| » Lost to Indians (11-17), 3-0 | Fenway Park (10-5) | 14-17 | Lost 5 |
| » Starters: Sam McDowell vs Gary Peters | Fourth | 8½ out |
| Saturday, May 16 |
| » Defeated Indians (11-18), 6-2 | Fenway Park (11-5) | 15-17 | |
| » Starters: Dean Chance vs Ray Culp | Fourth | 8½ out |
| Tuesday, May 19 |
| » Defeated Tigers (15-17), 5-4 | Fenway Park (12-5) | 16-17 | Won 2 |
| » Starters: Joe Niekro vs Mike Nagy | Third | 8 out |
| Wednesday, May 20 |
| » Lost to Indians (12-20), 7-2 | Cleveland Stadium (0-1) | 16-18 | |
| » Starters: Sonny Siebert vs Sam McDowell | Fourth | 8 out |
| Thursday, May 21 |
| » Lost to Indians (13-20), 10-7 | Cleveland Stadium (0-2) | 16-19 | Lost 2 |
| » Starters: Bill Lee vs Bob Miller | Fourth | 8½ out |
| Future Red Sox Bryce Florie is born in Charleston, SC. |
| Friday, May 22 |
| » Lost to Orioles (27-12), 7-4 | Memorial Stadium (0-1) | 16-20 | Lost 3 |
| » Starters: Gary Peters vs Jim Hardin | Fourth | 9½ out |
| Saturday, May 23 |
| » Lost to Orioles (28-12), 3-0 | Memorial Stadium (0-2) | 16-21 | Lost 4 |
| » Starters: Ray Culp vs Jim Palmer | Fifth | 10½ out |
| Sunday, May 24 |
| » Lost to Orioles (29-12), 2-1 | Memorial Stadium (0-3) | 16-22 | Lost 5 |
| » Starters: Mike Nagy vs Mike Cuellar | Fifth | 10½ out |
| » Defeated Orioles (29-13), 4-3 | Memorial Stadium (1-3) | 17-22 | |
| » Starters: Sonny Siebert vs Tom Phoebus | Fifth | 10½ out |
| Former Red Sox Bill Lamar dies in Rockport, MA at the age of 74. |
| Monday, May 25 |
| » Defeated Senators (18-23), 5-3 | Fenway Park (13-5) | 18-22 | Won 2 |
| » Starters: Dick Bosman vs Bill Lee | Fourth | 10½ out |
| Future Red Sox Luis Ortiz is born in Santo Domingo, D.R. |
| Tuesday, May 26 |
| » Lost to Senators (19-23), 7-5 | Fenway Park (13-6) | 18-23 | |
| » Starters: Joe Grzenda vs Gary Peters | Fifth | 11½ out |
| Wednesday, May 27 |
| » Lost to Senators (20-23), 7-5 | Fenway Park (13-7) | 18-24 | Lost 2 |
| » Starters: Jim Hannan vs Ray Culp | Fifth | 12½ out |
| Friday, May 29 |
| » Defeated White Sox (17-28), 4-3 | Fenway Park (14-7) | 19-24 | |
| » Starters: Tommy John vs Sonny Siebert | Fifth | 12½ out |
| Saturday, May 30 |
| » Defeated White Sox (17-29), 7-5 | Fenway Park (15-7) | 20-24 | Won 2 |
| » Starters: Bart Johnson vs Mike Nagy | Fifth | 11½ out |
| Sunday, May 31 |
| » Lost to White Sox (18-29), 22-13 | Fenway Park (15-8) | 20-25 | |
| » Starters: Jerry Janeski vs Gary Peters | Fifth | 11½ out |
| Tuesday, June 2 |
| » Defeated Twins (31-14), 5-1 | Fenway Park (16-8) | 21-25 | |
| » Starters: Jim Perry vs Ray Culp | Fifth | 11½ out |
| Thursday, June 4 |
| » Defeated Twins (31-15), 5-1 | Fenway Park (17-8) | 22-25 | Won 2 |
| » Starters: Jim Kaat vs Sonny Siebert | Fifth | 10 out |
| Friday, June 5 |
| » Defeated Royals (19-31), 4-2 | Fenway Park (18-8) | 23-25 | Won 3 |
| » Starters: Bill Butler vs Mike Nagy | Fourth | 10 out |
| Sunday, June 7 |
| » Defeated Royals (19-32), 7-4 | Fenway Park (19-8) | 24-25 | Won 4 |
| » Starters: Dave Morehead vs Ray Culp | Third | 9 out |
| » Defeated Royals (19-33), 5-2 | Fenway Park (20-8) | 25-25 | Won 5 |
| » Starters: Bob Johnson vs Gary Peters | Third | 9 out |
| Tuesday, June 9 |
| » Lost to White Sox (21-34), 4-2 | Comiskey Park I (0-1) | 25-26 | |
| » Starters: Sonny Siebert vs Jerry Janeski | Third | 9 out |
| Wednesday, June 10 |
| » Defeated White Sox (21-35), 7-6 | Comiskey Park I (1-1) | 26-26 | |
| » Starters: Mike Nagy vs Joe Horlen | Third | 9 out |
| Thursday, June 11 |
| Future Red Sox Bill Selby is born in Monroeville, AL. |
| Friday, June 12 |
| » Lost to Twins (35-17), 5-2 | Metropolitan Stadium (0-1) | 26-27 | |
| » Starters: Gary Peters vs Jim Perry | Fourth | 9½ out |
| Future Red Sox Damon Buford is born in Baltimore, MD. |
| Saturday, June 13 |
| » Defeated Twins (35-18), 6-4 | Metropolitan Stadium (1-1) | 27-27 | |
| » Starters: Ray Culp vs Jim Kaat | Fourth | 8½ out |
| Sunday, June 14 |
| » Lost to Twins (36-18), 10-2 | Metropolitan Stadium (1-2) | 27-28 | |
| » Starters: Sonny Siebert vs Bert Blyleven | Fourth | 9½ out |
| Monday, June 15 |
| » Lost to Royals (21-37), 7-6 | Municipal Stadium (0-1) | 27-29 | Lost 2 |
| » Starters: Mike Nagy vs Jim Rooker | Fourth | 9½ out |
| Tuesday, June 16 |
| » Defeated Royals (21-38), 7-5 | Municipal Stadium (1-1) | 28-29 | |
| » Starters: Gary Peters vs Bill Butler | Fourth | 9 out |
| Wednesday, June 17 |
| » Defeated Royals (21-39), 3-1 | Municipal Stadium (2-1) | 29-29 | Won 2 |
| » Starters: Ken Brett vs Dave Morehead | Fourth | 8 out |
| Thursday, June 18 |
| » Lost to Yankees (38-25), 3-2 | Fenway Park (20-9) | 29-30 | |
| » Starters: Gary Waslewski vs Ray Culp | Fourth | 8½ out |
| Friday, June 19 |
| » Defeated Yankees (38-26), 7-4 | Fenway Park (21-9) | 30-30 | |
| » Starters: Stan Bahnsen vs Sonny Siebert | Fourth | 9 out |
| Saturday, June 20 |
| » Lost to Yankees (39-26), 8-3 | Fenway Park (21-10) | 30-31 | |
| » Starters: Mel Stottlemyre vs Mike Nagy | Fourth | 10 out |
| Sunday, June 21 |
| » Lost to Yankees (40-26), 14-10 | Fenway Park (21-11) | 30-32 | Lost 2 |
| » Starters: Fritz Peterson vs Gary Peters | Fourth | 11 out |
| Monday, June 22 |
| » Lost to Orioles (44-23), 9-8 | Fenway Park (21-12) | 30-33 | Lost 3 |
| » Starters: Tom Phoebus vs Ken Brett | Fourth | 12 out |
| Tuesday, June 23 |
| » Defeated Orioles (44-24), 5-1 | Fenway Park (22-12) | 31-33 | |
| » Starters: Jim Palmer vs Ray Culp | Fourth | 11 out |
| Wednesday, June 24 |
| » Defeated Orioles (44-25), 6-5 | Fenway Park (23-12) | 32-33 | Won 2 |
| » Starters: Jim Hardin vs Sonny Siebert | Fourth | 10 out |
| Thursday, June 25 |
| » Lost to Orioles (45-25), 13-8 | Fenway Park (23-13) | 32-34 | |
| » Starters: Mike Cuellar vs Mike Nagy | Fourth | 11 out |
| Future Red Sox Aaron Sele is born in Golden Valley, MN. |
| Saturday, June 27 |
| » Defeated Yankees (42-28), 4-0 | Yankee Stadium (2-1) | 33-34 | |
| » Starters: Gary Peters vs Gary Waslewski | Fourth | 10½ out |
| Sunday, June 28 |
| » Defeated Yankees (42-29), 5-3 | Yankee Stadium (3-1) | 34-34 | Won 2 |
| » Starters: Ken Brett vs Mel Stottlemyre | Fourth | 10 out |
| » Lost to Yankees (43-29), 8-2 | Yankee Stadium (3-2) | 34-35 | |
| » Starters: Ray Culp vs Stan Bahnsen | Fourth | 10 out |
| Tuesday, June 30 |
| » Lost to Senators (34-40), 3-1 | Fenway Park (23-14) | 34-36 | Lost 2 |
| » Starters: Dick Bosman vs Sonny Siebert | Fourth | 10½ out |
| Wednesday, July 1 |
| » Defeated Senators (34-41), 6-5 | Fenway Park (24-14) | 35-36 | |
| » Starters: Joe Coleman vs Mike Nagy | Fourth | 10½ out |
| Thursday, July 2 |
| » Defeated Senators (34-42), 5-0 | Fenway Park (25-14) | 36-36 | Won 2 |
| » Starters: Dick Such vs Gary Peters | Fourth | 9½ out |
| » Major-league debuts: Jackie Brown (Senators) |
| Friday, July 3 |
| » Defeated Indians (33-41), 2-1 | Fenway Park (26-14) | 37-36 | Won 3 |
| » Starters: Rich Hand vs Ray Culp | Fourth | 9 out |
| » Defeated Indians (33-42), 5-4 | Fenway Park (27-14) | 38-36 | Won 4 |
| » Starters: Mike Paul vs Ken Brett | Fourth | 9 out |
| Saturday, July 4 |
| » Defeated Indians (33-43), 5-1 | Fenway Park (28-14) | 39-36 | Won 5 |
| » Starters: Steve Dunning vs Sonny Siebert | Fourth | 8 out |
| Sunday, July 5 |
| » Defeated Indians (33-44), 8-4 | Fenway Park (29-14) | 40-36 | Won 6 |
| » Starters: Rick Austin vs Mike Nagy | Fourth | 8 out |
| Monday, July 6 |
| » Lost to Tigers (42-35), 6-3 | Tiger Stadium (0-3) | 40-37 | |
| » Starters: Gary Peters vs Les Cain | Fourth | 8½ out |
| Tuesday, July 7 |
| » Defeated Tigers (42-36), 8-4 | Tiger Stadium (1-3) | 41-37 | |
| » Starters: Ray Culp vs Earl Wilson | Fourth | 9 out |
| » Lost to Tigers (43-36), 4-3 | Tiger Stadium (1-4) | 41-38 | |
| » Starters: Ken Brett vs Joe Niekro | Fourth | 9 out |
| Former Red Sox Harry Wolter dies in Palo Alto, CA at the age of 86. |
| Wednesday, July 8 |
| » Lost to Tigers (44-36), 3-2 | Tiger Stadium (1-5) | 41-39 | Lost 2 |
| » Starters: Sonny Siebert vs Mickey Lolich | Fourth | 10 out |
| Thursday, July 9 |
| » Lost to Tigers (45-36), 7-3 | Tiger Stadium (1-6) | 41-40 | Lost 3 |
| » Starters: Mike Nagy vs Denny McLain | Fourth | 10 out |
| Friday, July 10 |
| » Defeated Indians (37-46), 7-1 | Cleveland Stadium (1-2) | 42-40 | |
| » Starters: Gary Peters vs Rich Hand | Fourth | 9 out |
| Saturday, July 11 |
| » Lost to Indians (38-46), 3-1 | Cleveland Stadium (1-3) | 42-41 | |
| » Starters: Ken Brett vs Sam McDowell | Fourth | 10 out |
| Future Red Sox Billy Ashley is born in Trenton, MI. |
| Sunday, July 12 |
| » Defeated Indians (38-47), 6-2 | Cleveland Stadium (2-3) | 43-41 | |
| » Starters: Ray Culp vs Steve Dunning | Fourth | 9 out |
| » Defeated Indians (38-48), 8-2 | Cleveland Stadium (3-3) | 44-41 | Won 2 |
| » Starters: Sonny Siebert vs Fred Lasher | Fourth | 9 out |
| Tuesday, July 14 |
| Future Red Sox Mark Brandenburg is born in Houston, TX. |
| Thursday, July 16 |
| » Defeated Brewers (32-58), 6-5 | Fenway Park (30-14) | 45-41 | Won 3 |
| » Starters: Skip Lockwood vs Mike Nagy | Fourth | 9 out |
| Friday, July 17 |
| » Defeated Brewers (32-59), 8-2 | Fenway Park (31-14) | 46-41 | Won 4 |
| » Starters: Gene Brabender vs Sonny Siebert | Fourth | 8 out |
| Saturday, July 18 |
| » Lost to Brewers (33-59), 10-5 | Fenway Park (31-15) | 46-42 | |
| » Starters: Lew Krausse vs Gary Peters | Fourth | 8 out |
| Sunday, July 19 |
| » Defeated Athletics (48-44), 9-4 | Fenway Park (32-15) | 47-42 | |
| » Starters: Rollie Fingers vs Ray Culp | Fourth | 7½ out |
| Monday, July 20 |
| » Lost to Athletics (49-44), 3-2 | Fenway Park (32-16) | 47-43 | |
| » Starters: Chuck Dobson vs Ken Brett | Fourth | 8½ out |
| Tuesday, July 21 |
| » Lost to Angels (56-37), 10-6 | Fenway Park (32-17) | 47-44 | Lost 2 |
| » Starters: Clyde Wright vs Mike Nagy | Fourth | 9½ out |
| » Major-league debuts: Carmen Fanzone (Red Sox) |
| Wednesday, July 22 |
| » Defeated Angels (56-38), 7-4 | Fenway Park (33-17) | 48-44 | |
| » Starters: Tom Bradley vs Gary Peters | Fourth | 9 out |
| » Defeated Angels (56-39), 8-3 | Fenway Park (34-17) | 49-44 | Won 2 |
| » Starters: Mel Queen vs Sonny Siebert | Fourth | 9 out |
| Thursday, July 23 |
| » Lost to Angels (57-39), 4-1 | Fenway Park (34-18) | 49-45 | |
| » Starters: Greg Garrett vs Vicente Romo | Fourth | 10 out |
| Friday, July 24 |
| » Lost to Brewers (35-62), 8-4 | County Stadium (1-3) | 49-46 | Lost 2 |
| » Starters: Ray Culp vs Lew Krausse | Fourth | 10 out |
| Saturday, July 25 |
| » Lost to Brewers (36-62), 6-2 | County Stadium (1-4) | 49-47 | Lost 3 |
| » Starters: Mike Nagy vs Marty Pattin | Fourth | 11 out |
| Former Red Sox Herb Hunter dies in Orlando, FL at the age of 74. |
| Sunday, July 26 |
| » Defeated Brewers (36-63), 12-5 | County Stadium (2-4) | 50-47 | |
| » Starters: Gary Peters vs Skip Lockwood | Fourth | 11 out |
| Tuesday, July 28 |
| » Lost to Athletics (55-44), 6-4 | Oakland-Alameda County Stadium (1-3) | 50-48 | |
| » Starters: Vicente Romo vs Chuck Dobson | Fourth | 11½ out |
| Wednesday, July 29 |
| » Defeated Athletics (55-45), 4-1 | Oakland-Alameda County Stadium (2-3) | 51-48 | |
| » Starters: Ray Culp vs Diego Segui | Fourth | 10½ out |
| Thursday, July 30 |
| » Lost to Athletics (56-45), 2-1 | Oakland-Alameda County Stadium (2-4) | 51-49 | |
| » Starters: Cal Koonce vs Catfish Hunter | Fourth | 11 out |
| Friday, July 31 |
| » Defeated Angels (58-45), 2-0 | Anaheim Stadium (1-3) | 52-49 | |
| » Starters: Sonny Siebert vs Tom Murphy | Fourth | 11 out |
| Saturday, August 1 |
| » Defeated Angels (58-46), 8-0 | Anaheim Stadium (2-3) | 53-49 | Won 2 |
| » Starters: Gary Peters vs Greg Garrett | Third | 11 out |
| Sunday, August 2 |
| » Lost to Angels (59-46), 8-3 | Anaheim Stadium (2-4) | 53-50 | |
| » Starters: Vicente Romo vs Tom Bradley | Third | 12 out |
| Tuesday, August 4 |
| » Lost to Orioles (67-39), 5-2 | Memorial Stadium (1-4) | 53-51 | Lost 2 |
| » Starters: Ray Culp vs Dave McNally | Fourth | 13 out |
| Wednesday, August 5 |
| » Lost to Orioles (68-39), 3-0 | Memorial Stadium (1-5) | 53-52 | Lost 3 |
| » Starters: Sonny Siebert vs Jim Palmer | Fourth | 14 out |
| Thursday, August 6 |
| » Lost to Senators (50-59), 5-2 | Robert F. Kennedy Stadium (1-3) | 53-53 | Lost 4 |
| » Starters: Gary Peters vs Casey Cox | Fourth | 14½ out |
| Friday, August 7 |
| » Defeated Senators (50-60), 3-1 | Robert F. Kennedy Stadium (2-3) | 54-53 | |
| » Starters: Cal Koonce vs Jim Hannan | Fourth | 13½ out |
| Future Red Sox Rick Croushore is born in Lakehurst, NJ. Future Red Sox Greg Pirkl is born in Long Beach, CA. |
| Saturday, August 8 |
| » Lost to Tigers (60-51), 6-5 | Fenway Park (34-19) | 54-54 | |
| » Starters: Denny McLain vs Vicente Romo | Fourth | 14½ out |
| Sunday, August 9 |
| » Defeated Tigers (60-52), 7-4 | Fenway Park (35-19) | 55-54 | |
| » Starters: Mickey Lolich vs Ray Culp | Fourth | 14 out |
| Future Red Sox Pat Mahomes is born in Bryan, TX. |
| Monday, August 10 |
| » Defeated Tigers (60-53), 11-10 | Fenway Park (36-19) | 56-54 | Won 2 |
| » Starters: Joe Niekro vs Sonny Siebert | Fourth | 13½ out |
| Wednesday, August 12 |
| » Defeated Royals (42-72), 7-4 | Fenway Park (37-19) | 57-54 | Won 3 |
| » Starters: Jim Rooker vs Gary Peters | Fourth | 14½ out |
| » Lost to Royals (43-72), 4-3 | Fenway Park (37-20) | 57-55 | |
| » Starters: Bob Johnson vs Cal Koonce | Fourth | 14½ out |
| Thursday, August 13 |
| » Lost to Royals (44-72), 11-3 | Fenway Park (37-21) | 57-56 | Lost 2 |
| » Starters: Al Fitzmorris vs Vicente Romo | Fourth | 14½ out |
| » Major-league debuts: John Curtis (Red Sox) |
| Friday, August 14 |
| » Defeated Twins (69-45), 8-1 | Fenway Park (38-21) | 58-56 | |
| » Starters: Bill Zepp vs Ray Culp | Fourth | 13½ out |
| Saturday, August 15 |
| » Defeated Twins (69-46), 5-3 | Fenway Park (39-21) | 59-56 | Won 2 |
| » Starters: Jim Perry vs Sonny Siebert | Fourth | 13 out |
| » Defeated Twins (69-47), 11-7 | Fenway Park (40-21) | 60-56 | Won 3 |
| » Starters: Bert Blyleven vs Ken Brett | Fourth | 13 out |
| Future Red Sox Tony Rodriguez is born in Rio Piedras, P.R. |
| Sunday, August 16 |
| » Lost to Twins (70-47), 9-6 | Fenway Park (40-22) | 60-57 | |
| » Starters: Luis Tiant vs Gary Peters | Fourth | 14 out |
| Monday, August 17 |
| » Defeated White Sox (43-80), 7-2 | Fenway Park (41-22) | 61-57 | |
| » Starters: Bart Johnson vs Cal Koonce | Fourth | 14 out |
| Tuesday, August 18 |
| » Defeated White Sox (43-81), 8-4 | Fenway Park (42-22) | 62-57 | Won 2 |
| » Starters: Bob Miller vs Vicente Romo | Fourth | 14 out |
| Wednesday, August 19 |
| » Lost to White Sox (44-81), 13-5 | Fenway Park (42-23) | 62-58 | |
| » Starters: Tommy John vs Ray Culp | Fourth | 15 out |
| Friday, August 21 |
| » Lost to Royals (47-76), 2-1 | Municipal Stadium (2-2) | 62-59 | Lost 2 |
| » Starters: Sonny Siebert vs Wally Bunker | Fourth | 16 out |
| Saturday, August 22 |
| » Defeated Royals (47-77), 8-1 | Municipal Stadium (3-2) | 63-59 | |
| » Starters: Gary Peters vs Jim Rooker | Fourth | 15 out |
| Sunday, August 23 |
| » Lost to Royals (48-77), 4-3 | Municipal Stadium (3-3) | 63-60 | |
| » Starters: Cal Koonce vs Bob Johnson | Fourth | 16 out |
| Tuesday, August 25 |
| » Defeated Twins (73-51), 1-0 | Metropolitan Stadium (2-2) | 64-60 | |
| » Starters: Vicente Romo vs Bill Zepp | Fourth | 16 out |
| Wednesday, August 26 |
| » Lost to Twins (74-51), 7-0 | Metropolitan Stadium (2-3) | 64-61 | |
| » Starters: Ray Culp vs Bert Blyleven | Fourth | 17 out |
| Thursday, August 27 |
| » Lost to Twins (75-51), 5-2 | Metropolitan Stadium (2-4) | 64-62 | Lost 2 |
| » Starters: Sonny Siebert vs Jim Perry | Fourth | 18 out |
| Friday, August 28 |
| » Defeated White Sox (48-84), 5-4 | Comiskey Park I (2-1) | 65-62 | |
| » Starters: Gary Peters vs Tommy John | Fourth | 17½ out |
| Saturday, August 29 |
| » Lost to White Sox (49-84), 13-9 | Comiskey Park I (2-2) | 65-63 | |
| » Starters: Cal Koonce vs Bart Johnson | Fourth | 18½ out |
| Sunday, August 30 |
| » Defeated White Sox (49-85), 21-11 | Comiskey Park I (3-2) | 66-63 | |
| » Starters: Vicente Romo vs Jerry Janeski | Fourth | 17 out |
| » Defeated White Sox (49-86), 4-1 | Comiskey Park I (4-2) | 67-63 | Won 2 |
| » Starters: Mike Nagy vs Jim Magnuson | Fourth | 17 out |
| Monday, August 31 |
| » Defeated Tigers (69-63), 4-2 | Fenway Park (43-23) | 68-63 | Won 3 |
| » Starters: Mickey Lolich vs Ray Culp | Fourth | 17 out |
| Tuesday, September 1 |
| » Lost to Tigers (70-63), 10-9 | Fenway Park (43-24) | 68-64 | |
| » Starters: Mike Kilkenny vs Sonny Siebert | Fourth | 17 out |
| Wednesday, September 2 |
| » Lost to Tigers (71-63), 6-4 | Fenway Park (43-25) | 68-65 | Lost 2 |
| » Starters: Bob Reed vs Gary Peters | Fourth | 16½ out |
| » Defeated Tigers (71-64), 10-1 | Fenway Park (44-25) | 69-65 | |
| » Starters: Les Cain vs Cal Koonce | Fourth | 16½ out |
| » Major-league debuts: Gene Lamont (Tigers) |
| Thursday, September 3 |
| » Defeated Tigers (71-65), 5-2 | Fenway Park (45-25) | 70-65 | Won 2 |
| » Starters: Joe Niekro vs Ken Brett | Fourth | 16½ out |
| Friday, September 4 |
| » Lost to Orioles (88-49), 8-6 | Fenway Park (45-26) | 70-66 | |
| » Starters: Mike Cuellar vs Mike Nagy | Fourth | 17½ out |
| Saturday, September 5 |
| » Lost to Orioles (89-49), 3-2 | Fenway Park (45-27) | 70-67 | Lost 2 |
| » Starters: Tom Phoebus vs Ray Culp | Fourth | 18½ out |
| Sunday, September 6 |
| » Defeated Orioles (89-50), 9-8 | Fenway Park (46-27) | 71-67 | |
| » Starters: Dave McNally vs Sonny Siebert | Fourth | 17½ out |
| » Major-league debuts: Bob Montgomery (Red Sox) |
| Monday, September 7 |
| » Defeated Indians (66-74), 4-3 | Cleveland Stadium (4-3) | 72-67 | Won 2 |
| » Starters: Gary Peters vs Sam McDowell | Fourth | 17 out |
| » Lost to Indians (67-74), 8-2 | Cleveland Stadium (4-4) | 72-68 | |
| » Starters: Cal Koonce vs Dean Chance | Fourth | 17 out |
| Tuesday, September 8 |
| » Defeated Indians (67-75), 4-3 | Cleveland Stadium (5-4) | 73-68 | |
| » Starters: Ken Brett vs Steve Hargan | Fourth | 17 out |
| Wednesday, September 9 |
| » Defeated Tigers (74-68), 4-1 | Tiger Stadium (2-6) | 74-68 | Won 2 |
| » Starters: Mike Nagy vs Mike Kilkenny | Third | 17 out |
| Thursday, September 10 |
| » Defeated Tigers (74-69), 14-0 | Tiger Stadium (3-6) | 75-68 | Won 3 |
| » Starters: Ray Culp vs Les Cain | Third | 17 out |
| Friday, September 11 |
| » Lost to Orioles (93-51), 3-2 | Memorial Stadium (1-6) | 75-69 | |
| » Starters: Sonny Siebert vs Jim Palmer | Third | 18 out |
| Saturday, September 12 |
| » Lost to Orioles (94-51), 5-1 | Memorial Stadium (1-7) | 75-70 | Lost 2 |
| » Starters: Gary Peters vs Tom Phoebus | Third | 19 out |
| Sunday, September 13 |
| » Lost to Orioles (95-51), 13-2 | Memorial Stadium (1-8) | 75-71 | Lost 3 |
| » Starters: Ken Brett vs Mike Cuellar | Third | 20 out |
| » Major-league debuts: Roger Moret (Red Sox) |
| Tuesday, September 15 |
| » Lost to Yankees (82-65), 8-6 | Yankee Stadium (3-3) | 75-72 | Lost 4 |
| » Starters: Ray Culp vs Stan Bahnsen | Fourth | 21½ out |
| » Lost to Yankees (83-65), 3-2 | Yankee Stadium (3-4) | 75-73 | Lost 5 |
| » Starters: Mike Nagy vs Steve Kline | Fourth | 21½ out |
| Wednesday, September 16 |
| » Defeated Yankees (83-66), 3-1 | Yankee Stadium (4-4) | 76-73 | |
| » Starters: Sonny Siebert vs Fritz Peterson | Fourth | 20½ out |
| Thursday, September 17 |
| » Defeated Yankees (83-67), 5-4 | Yankee Stadium (5-4) | 77-73 | Won 2 |
| » Starters: Gary Peters vs Mel Stottlemyre | Third | 19½ out |
| Saturday, September 19 |
| » Defeated Senators (70-79), 7-3 | Fenway Park (47-27) | 78-73 | Won 3 |
| » Starters: Joe Coleman vs Ken Brett | Third | 18½ out |
| » Defeated Senators (70-80), 11-3 | Fenway Park (48-27) | 79-73 | Won 4 |
| » Starters: Jim Hannan vs Mike Nagy | Third | 18½ out |
| Sunday, September 20 |
| » Defeated Senators (70-81), 3-1 | Fenway Park (49-27) | 80-73 | Won 5 |
| » Starters: Jim Shellenback vs Ray Culp | |
