| Friday, January 16 |
| Future Padre Ron Villone is born in Englewood, NJ. |
| Friday, January 23 |
| Future Padre Alan Embree is born in The Dalles, OR. |
| Wednesday, April 1 |
| Future Padre Matt Herges is born in Champaign, IL. |
| Monday, April 6 |
| » Major-league debuts: Dick Such (Senators) |
| Tuesday, April 7 |
| » Defeated Braves (0-1), 8-3 | San Diego/Jack Murphy Stadium (1-0) | 1-0 | |
| » Starters: Phil Niekro vs Pat Dobson | Second | ½ out |
| Wednesday, April 8 |
| » Lost to Braves (1-1), 6-1 | San Diego/Jack Murphy Stadium (1-1) | 1-1 | |
| » Starters: Pat Jarvis vs Al Santorini | Second | 1½ out |
| Thursday, April 9 |
| » Lost to Braves (2-1), 6-1 | San Diego/Jack Murphy Stadium (1-2) | 1-2 | Lost 2 |
| » Starters: Jim Nash vs Clay Kirby | Third | 2½ out |
| Friday, April 10 |
| » Defeated Dodgers (0-4), 7-2 | Dodger Stadium (1-0) | 2-2 | |
| » Starters: Mike Corkins vs Alan Foster | Third | 1½ out |
| Saturday, April 11 |
| » Defeated Dodgers (0-5), 4-0 | Dodger Stadium (2-0) | 3-2 | Won 2 |
| » Starters: Danny Coombs vs Claude Osteen | Third | 1 out |
| Future Padre Sean Bergman is born in Joliet, IL. Future Padre Joe Vitiello is born in Cambridge, MA. |
| Sunday, April 12 |
| » Lost to Dodgers (1-5), 6-0 | Dodger Stadium (2-1) | 3-3 | |
| » Starters: Pat Dobson vs Bill Singer | Third | 2 out |
| Monday, April 13 |
| » Defeated Reds (6-3), 3-1 | Crosley Field (1-0) | 4-3 | |
| » Starters: Al Santorini vs Jim McGlothlin | Second | 1 out |
| Tuesday, April 14 |
| » Lost to Reds (7-3), 6-1 | Crosley Field (1-1) | 4-4 | |
| » Starters: Clay Kirby vs Wayne Simpson | Third | 2 out |
| Wednesday, April 15 |
| » Lost to Braves (5-4), 7-5 | Atlanta-Fulton County Stadium (0-1) | 4-5 | Lost 2 |
| » Starters: Mike Corkins vs George Stone | Fourth | 3 out |
| Thursday, April 16 |
| » Defeated Braves (5-5), 5-4 | Atlanta-Fulton County Stadium (1-1) | 5-5 | |
| » Starters: Pat Dobson vs Phil Niekro | Third | 3 out |
| Friday, April 17 |
| » Lost to Astros (5-6), 4-1 | Astrodome (0-1) | 5-6 | |
| » Starters: Dave Roberts vs Larry Dierker | Fourth | 4 out |
| Saturday, April 18 |
| » Lost to Astros (6-6), 4-3 | Astrodome (0-2) | 5-7 | Lost 2 |
| » Starters: Danny Coombs vs Denny Lemaster | Fifth | 4 out |
| Sunday, April 19 |
| » Lost to Astros (7-6), 5-1 | Astrodome (0-3) | 5-8 | Lost 3 |
| » Starters: Al Santorini vs Tom Griffin | Fifth | 5 out |
| Tuesday, April 21 |
| » Defeated Mets (6-6), 5-3 | Shea Stadium (1-0) | 6-8 | |
| » Starters: Clay Kirby vs Gary Gentry | Fourth | 5½ out |
| Wednesday, April 22 |
| » Lost to Mets (7-6), 2-1 | Shea Stadium (1-1) | 6-9 | |
| » Starters: Mike Corkins vs Tom Seaver | Fifth | 6 out |
| Friday, April 24 |
| » Lost to Phillies (6-8), 5-4 | San Diego/Jack Murphy Stadium (1-3) | 6-10 | Lost 2 |
| » Starters: Grant Jackson vs Pat Dobson | Fifth | 6 out |
| Saturday, April 25 |
| » Lost to Phillies (7-8), 1-0 | San Diego/Jack Murphy Stadium (1-4) | 6-11 | Lost 3 |
| » Starters: Jim Bunning vs Al Santorini | Fifth | 7 out |
| Sunday, April 26 |
| » Lost to Phillies (8-8), 3-2 | San Diego/Jack Murphy Stadium (1-5) | 6-12 | Lost 4 |
| » Starters: Chris Short vs Clay Kirby | Sixth | 7 out |
| Tuesday, April 28 |
| » Lost to Expos (4-11), 4-2 | San Diego/Jack Murphy Stadium (1-6) | 6-13 | Lost 5 |
| » Starters: Gary Waslewski vs Mike Corkins | Sixth | 8½ out |
| » Lost to Expos (5-11), 7-3 | San Diego/Jack Murphy Stadium (1-7) | 6-14 | Lost 6 |
| » Starters: Steve Renko vs Danny Coombs | Sixth | 8½ out |
| Wednesday, April 29 |
| » Defeated Expos (5-12), 10-0 | San Diego/Jack Murphy Stadium (2-7) | 7-14 | |
| » Starters: Joe Sparma vs Pat Dobson | Fifth | 8½ out |
| » Major-league debuts: John Strohmayer (Expos) |
| Friday, May 1 |
| » Lost to Mets (11-9), 2-1 | San Diego/Jack Murphy Stadium (2-8) | 7-15 | |
| » Starters: Tom Seaver vs Al Santorini | Sixth | 9½ out |
| Saturday, May 2 |
| » Defeated Mets (11-10), 5-4 | San Diego/Jack Murphy Stadium (3-8) | 8-15 | |
| » Starters: Jim McAndrew vs Clay Kirby | Sixth | 9½ out |
| Sunday, May 3 |
| » Defeated Mets (11-11), 4-3 | San Diego/Jack Murphy Stadium (4-8) | 9-15 | Won 2 |
| » Starters: Jerry Koosman vs Mike Corkins | Fifth | 10 out |
| » Lost to Mets (12-11), 3-2 | San Diego/Jack Murphy Stadium (4-9) | 9-16 | |
| » Starters: Gary Gentry vs Pat Dobson | Fifth | 10 out |
| Tuesday, May 5 |
| » Defeated Phillies (12-12), 11-8 | Shibe Park (1-0) | 10-16 | |
| » Starters: Al Santorini vs Grant Jackson | Sixth | 10½ out |
| Wednesday, May 6 |
| » Lost to Phillies (13-12), 4-3 | Shibe Park (1-1) | 10-17 | |
| » Starters: Clay Kirby vs Jim Bunning | Sixth | 11 out |
| » Major-league debuts: Del Bates (Phillies) |
| Thursday, May 7 |
| » Defeated Phillies (13-13), 8-2 | Shibe Park (2-1) | 11-17 | |
| » Starters: Pat Dobson vs Chris Short | Sixth | 11 out |
| Friday, May 8 |
| » Defeated Expos (7-17), 11-1 | Parc Jarry (1-0) | 12-17 | Won 2 |
| » Starters: Mike Corkins vs Gary Waslewski | Sixth | 10½ out |
| » Lost to Expos (8-17), 7-6 | Parc Jarry (1-1) | 12-18 | |
| » Starters: Al Santorini vs Steve Renko | Sixth | 10½ out |
| Saturday, May 9 |
| » Defeated Expos (8-18), 6-0 | Parc Jarry (2-1) | 13-18 | |
| » Starters: Danny Coombs vs Bill Stoneman | Sixth | 9½ out |
| Sunday, May 10 |
| » Defeated Expos (8-19), 5-4 | Parc Jarry (3-1) | 14-18 | Won 2 |
| » Starters: Clay Kirby vs Joe Sparma | Fifth | 9½ out |
| Monday, May 11 |
| » Lost to Giants (16-16), 6-5 | San Diego/Jack Murphy Stadium (4-10) | 14-19 | |
| » Starters: Gaylord Perry vs Pat Dobson | Sixth | 9½ out |
| Tuesday, May 12 |
| » Defeated Giants (16-17), 6-5 | San Diego/Jack Murphy Stadium (5-10) | 15-19 | |
| » Starters: Miguel Puente vs Mike Corkins | Sixth | 9½ out |
| Wednesday, May 13 |
| » Lost to Giants (17-17), 5-1 | San Diego/Jack Murphy Stadium (5-11) | 15-20 | |
| » Starters: Rich Robertson vs Danny Coombs | Sixth | 10 out |
| Thursday, May 14 |
| » Lost to Astros (17-17), 3-1 | San Diego/Jack Murphy Stadium (5-12) | 15-21 | Lost 2 |
| » Starters: Larry Dierker vs Clay Kirby | Sixth | 10½ out |
| Friday, May 15 |
| » Defeated Astros (17-18), 10-8 | San Diego/Jack Murphy Stadium (6-12) | 16-21 | |
| » Starters: Scipio Spinks vs Dave Roberts | Sixth | 9½ out |
| Saturday, May 16 |
| » Lost to Astros (18-18), 9-7 | San Diego/Jack Murphy Stadium (6-13) | 16-22 | |
| » Starters: Don Wilson vs Pat Dobson | Sixth | 10½ out |
| Sunday, May 17 |
| » Defeated Astros (18-19), 5-3 | San Diego/Jack Murphy Stadium (7-13) | 17-22 | |
| » Starters: Denny Lemaster vs Mike Corkins | Sixth | 11 out |
| Monday, May 18 |
| » Lost to Dodgers (21-15), 4-3 | San Diego/Jack Murphy Stadium (7-14) | 17-23 | |
| » Starters: Sandy Vance vs Danny Coombs | Sixth | 11 out |
| Tuesday, May 19 |
| » Lost to Dodgers (22-15), 8-3 | San Diego/Jack Murphy Stadium (7-15) | 17-24 | Lost 2 |
| » Starters: Don Sutton vs Clay Kirby | Sixth | 12 out |
| Wednesday, May 20 |
| » Defeated Dodgers (22-16), 10-4 | San Diego/Jack Murphy Stadium (8-15) | 18-24 | |
| » Starters: Alan Foster vs Dave Roberts | Sixth | 11½ out |
| Thursday, May 21 |
| » Major-league debuts: Balor Moore (Expos) |
| Future Padre Bryce Florie is born in Charleston, SC. |
| Friday, May 22 |
| » Lost to Giants (19-22), 9-4 | Candlestick Park (0-1) | 18-25 | |
| » Starters: Mike Corkins vs Rich Robertson | Sixth | 13 out |
| Saturday, May 23 |
| » Defeated Giants (19-23), 17-16 | Candlestick Park (1-1) | 19-25 | |
| » Starters: Clay Kirby vs Juan Marichal | Sixth | 13 out |
| Future Padre Ricky Gutierrez is born in Miami, FL. |
| Sunday, May 24 |
| » Lost to Giants (20-23), 6-1 | Candlestick Park (1-2) | 19-26 | |
| » Starters: Ron Herbel vs Gaylord Perry | Sixth | 13½ out |
| » Lost to Giants (21-23), 7-6 | Candlestick Park (1-3) | 19-27 | Lost 2 |
| » Starters: Pat Dobson vs Mike McCormick | Sixth | 13½ out |
| Monday, May 25 |
| » Lost to Reds (32-12), 2-1 | San Diego/Jack Murphy Stadium (8-16) | 19-28 | Lost 3 |
| » Starters: Jim McGlothlin vs Clay Kirby | Sixth | 14½ out |
| Tuesday, May 26 |
| » Defeated Reds (32-13), 8-1 | San Diego/Jack Murphy Stadium (9-16) | 20-28 | |
| » Starters: Jim Merritt vs Mike Corkins | Sixth | 12½ out |
| » Defeated Reds (32-14), 4-1 | San Diego/Jack Murphy Stadium (10-16) | 21-28 | Won 2 |
| » Starters: Pedro Borbon vs Danny Coombs | Sixth | 12½ out |
| Wednesday, May 27 |
| » Lost to Reds (33-14), 6-4 | San Diego/Jack Murphy Stadium (10-17) | 21-29 | |
| » Starters: Wayne Simpson vs Gary Ross | Sixth | 13½ out |
| Saturday, May 30 |
| » Defeated Cubs (23-19), 11-4 | Wrigley Field (1-0) | 22-29 | |
| » Starters: Clay Kirby vs Ken Holtzman | Sixth | 14½ out |
| » Lost to Cubs (24-19), 8-7 | Wrigley Field (1-1) | 22-30 | |
| » Starters: Pat Dobson vs Joe Decker | Sixth | 14½ out |
| Sunday, May 31 |
| » Lost to Cubs (25-19), 7-4 | Wrigley Field (1-2) | 22-31 | Lost 2 |
| » Starters: Mike Corkins vs Fergie Jenkins | Sixth | 15½ out |
| Monday, June 1 |
| » Lost to Pirates (24-26), 5-1 | Forbes Field (0-1) | 22-32 | Lost 3 |
| » Starters: Danny Coombs vs Dock Ellis | Sixth | 16 out |
| Tuesday, June 2 |
| » Defeated Pirates (24-27), 14-8 | Forbes Field (1-1) | 23-32 | |
| » Starters: Gary Ross vs Bob Veale | Sixth | 16 out |
| Friday, June 5 |
| » Defeated Cardinals (23-25), 3-2 | Busch Stadium II (1-0) | 24-32 | Won 2 |
| » Starters: Pat Dobson vs Mike Torrez | Sixth | 15½ out |
| Saturday, June 6 |
| » Defeated Cardinals (23-26), 5-4 | Busch Stadium II (2-0) | 25-32 | Won 3 |
| » Starters: Mike Corkins vs Steve Carlton | Sixth | 15½ out |
| Sunday, June 7 |
| » Lost to Cardinals (24-26), 10-7 | Busch Stadium II (2-1) | 25-33 | |
| » Starters: Danny Coombs vs Bob Gibson | Sixth | 16½ out |
| Tuesday, June 9 |
| » Lost to Cubs (29-21), 7-3 | San Diego/Jack Murphy Stadium (10-18) | 25-34 | Lost 2 |
| » Starters: Fergie Jenkins vs Clay Kirby | Sixth | 17½ out |
| Wednesday, June 10 |
| » Defeated Cubs (29-22), 11-8 | San Diego/Jack Murphy Stadium (11-18) | 26-34 | |
| » Starters: Jim Colborn vs Pat Dobson | Sixth | 17½ out |
| Thursday, June 11 |
| » Lost to Cubs (30-22), 7-1 | San Diego/Jack Murphy Stadium (11-19) | 26-35 | |
| » Starters: Bill Hands vs Mike Corkins | Sixth | 17½ out |
| Friday, June 12 |
| » Lost to Pirates (29-29), 2-0 | San Diego/Jack Murphy Stadium (11-20) | 26-36 | Lost 2 |
| » Starters: Dock Ellis vs Dave Roberts | Sixth | 18 out |
| » Defeated Pirates (29-30), 5-2 | San Diego/Jack Murphy Stadium (12-20) | 27-36 | |
| » Starters: Bob Veale vs Danny Coombs | Sixth | 18 out |
| Saturday, June 13 |
| » Lost to Pirates (30-30), 7-2 | San Diego/Jack Murphy Stadium (12-21) | 27-37 | |
| » Starters: Steve Blass vs Al Santorini | Sixth | 18 out |
| Sunday, June 14 |
| » Defeated Pirates (30-31), 2-1 | San Diego/Jack Murphy Stadium (13-21) | 28-37 | |
| » Starters: Bob Moose vs Clay Kirby | Sixth | 18 out |
| Monday, June 15 |
| » Lost to Cardinals (27-30), 5-4 | San Diego/Jack Murphy Stadium (13-22) | 28-38 | |
| » Starters: Mike Torrez vs Pat Dobson | Sixth | 18½ out |
| Tuesday, June 16 |
| » Defeated Cardinals (27-31), 4-0 | San Diego/Jack Murphy Stadium (14-22) | 29-38 | |
| » Starters: Steve Carlton vs Mike Corkins | Fifth | 17½ out |
| Wednesday, June 17 |
| » Lost to Cardinals (28-31), 8-0 | San Diego/Jack Murphy Stadium (14-23) | 29-39 | |
| » Starters: Bob Gibson vs Danny Coombs | Fifth | 18½ out |
| Friday, June 19 |
| » Defeated Giants (29-35), 6-3 | San Diego/Jack Murphy Stadium (15-23) | 30-39 | |
| » Starters: Juan Marichal vs Al Santorini | Fifth | 17½ out |
| Saturday, June 20 |
| » Lost to Giants (30-35), 7-1 | San Diego/Jack Murphy Stadium (15-24) | 30-40 | |
| » Starters: Gaylord Perry vs Clay Kirby | Fifth | 18½ out |
| Sunday, June 21 |
| » Lost to Giants (31-35), 7-2 | San Diego/Jack Murphy Stadium (15-25) | 30-41 | Lost 2 |
| » Starters: Skip Pitlock vs Pat Dobson | Fifth | 19 out |
| Monday, June 22 |
| » Lost to Astros (29-40), 4-1 | Astrodome (0-4) | 30-42 | Lost 3 |
| » Starters: Dave Roberts vs Don Wilson | Sixth | 19 out |
| Tuesday, June 23 |
| » Lost to Astros (30-40), 2-1 | Astrodome (0-5) | 30-43 | Lost 4 |
| » Starters: Danny Coombs vs Jack Billingham | Sixth | 20 out |
| Wednesday, June 24 |
| » Lost to Astros (31-40), 5-4 | Astrodome (0-6) | 30-44 | Lost 5 |
| » Starters: Al Santorini vs Denny Lemaster | Sixth | 21 out |
| Friday, June 26 |
| » Lost to Dodgers (41-30), 4-1 | Dodger Stadium (2-2) | 30-45 | Lost 6 |
| » Starters: Clay Kirby vs Claude Osteen | Sixth | 22 out |
| Saturday, June 27 |
| » Lost to Dodgers (42-30), 7-5 | Dodger Stadium (2-3) | 30-46 | Lost 7 |
| » Starters: Pat Dobson vs Don Sutton | Sixth | 23 out |
| Sunday, June 28 |
| » Lost to Dodgers (43-30), 2-0 | Dodger Stadium (2-4) | 30-47 | Lost 8 |
| » Starters: Dave Roberts vs Alan Foster | Sixth | 24 out |
| Tuesday, June 30 |
| » Defeated Giants (36-38), 3-2 | Candlestick Park (2-3) | 31-47 | |
| » Starters: Danny Coombs vs Gaylord Perry | Sixth | 23 out |
| Wednesday, July 1 |
| » Lost to Giants (37-38), 12-7 | Candlestick Park (2-4) | 31-48 | |
| » Starters: Al Santorini vs Mike McCormick | Sixth | 24 out |
| Friday, July 3 |
| » Lost to Braves (38-37), 8-1 | Atlanta-Fulton County Stadium (1-2) | 31-49 | Lost 2 |
| » Starters: Clay Kirby vs Jim Nash | Sixth | 25½ out |
| » Lost to Braves (39-37), 9-4 | Atlanta-Fulton County Stadium (1-3) | 31-50 | Lost 3 |
| » Starters: Pat Dobson vs Phil Niekro | Sixth | 25½ out |
| Saturday, July 4 |
| » Lost to Braves (40-37), 2-1 | Atlanta-Fulton County Stadium (1-4) | 31-51 | Lost 4 |
| » Starters: Dave Roberts vs Pat Jarvis | Sixth | 26½ out |
| Sunday, July 5 |
| » Defeated Braves (40-38), 6-5 | Atlanta-Fulton County Stadium (2-4) | 32-51 | |
| » Starters: Danny Coombs vs Ron Reed | Sixth | 26½ out |
| Future Padre Doug Bochtler is born in West Palm Beach, FL. |
| Monday, July 6 |
| » Lost to Reds (58-23), 5-0 | Riverfront Stadium (0-1) | 32-52 | |
| » Starters: Al Santorini vs Jim Merritt | Sixth | 27½ out |
| Tuesday, July 7 |
| » Lost to Reds (59-23), 3-0 | Riverfront Stadium (0-2) | 32-53 | Lost 2 |
| » Starters: Pat Dobson vs Gary Nolan | Sixth | 28½ out |
| Wednesday, July 8 |
| » Defeated Reds (59-24), 3-1 | Riverfront Stadium (1-2) | 33-53 | |
| » Starters: Clay Kirby vs Jim McGlothlin | Sixth | 27½ out |
| Thursday, July 9 |
| » Defeated Reds (59-25), 10-9 | Riverfront Stadium (2-2) | 34-53 | Won 2 |
| » Starters: Dave Roberts vs Wayne Simpson | Sixth | 26½ out |
| Friday, July 10 |
| » Lost to Dodgers (51-33), 9-7 | San Diego/Jack Murphy Stadium (15-26) | 34-54 | |
| » Starters: Bill Singer vs Danny Coombs | Sixth | 27 out |
| Saturday, July 11 |
| » Defeated Dodgers (51-34), 4-3 | San Diego/Jack Murphy Stadium (16-26) | 35-54 | |
| » Starters: Claude Osteen vs Pat Dobson | Sixth | 27 out |
| Sunday, July 12 |
| » Defeated Dodgers (51-35), 4-1 | San Diego/Jack Murphy Stadium (17-26) | 36-54 | Won 2 |
| » Starters: Don Sutton vs Clay Kirby | Sixth | 27 out |
| Wednesday, July 15 |
| Future Padre Joey Long is born in Sidney, OH. |
| Thursday, July 16 |
| » Lost to Phillies (37-49), 10-7 | San Diego/Jack Murphy Stadium (17-27) | 36-55 | |
| » Starters: Woodie Fryman vs Pat Dobson | Sixth | 28 out |
| Friday, July 17 |
| » Lost to Phillies (38-49), 8-3 | San Diego/Jack Murphy Stadium (17-28) | 36-56 | Lost 2 |
| » Starters: Rick Wise vs Clay Kirby | Sixth | 28 out |
| Saturday, July 18 |
| » Lost to Phillies (39-49), 7-4 | San Diego/Jack Murphy Stadium (17-29) | 36-57 | Lost 3 |
| » Starters: Jim Bunning vs Earl Wilson | Sixth | 29 out |
| Sunday, July 19 |
| » Defeated Expos (38-53), 6-5 | San Diego/Jack Murphy Stadium (18-29) | 37-57 | |
| » Starters: Steve Renko vs Danny Coombs | Sixth | 28½ out |
| » Lost to Expos (39-53), 6-5 | San Diego/Jack Murphy Stadium (18-30) | 37-58 | |
| » Starters: Bill Stoneman vs Dave Roberts | Sixth | 28½ out |
| Monday, July 20 |
| » Defeated Expos (39-54), 3-1 | San Diego/Jack Murphy Stadium (19-30) | 38-58 | |
| » Starters: Mike Marshall vs Pat Dobson | Sixth | 29 out |
| Tuesday, July 21 |
| » Lost to Mets (50-43), 3-0 | San Diego/Jack Murphy Stadium (19-31) | 38-59 | |
| » Starters: Jim McAndrew vs Clay Kirby | Sixth | 30 out |
| Wednesday, July 22 |
| » Defeated Mets (50-44), 5-4 | San Diego/Jack Murphy Stadium (20-31) | 39-59 | |
| » Starters: Tom Seaver vs Earl Wilson | Sixth | 29 out |
| Friday, July 24 |
| » Lost to Phillies (44-50), 4-3 | Shibe Park (2-2) | 39-60 | |
| » Starters: Danny Coombs vs Grant Jackson | Sixth | 29½ out |
| Saturday, July 25 |
| » Lost to Phillies (45-50), 9-2 | Shibe Park (2-3) | 39-61 | Lost 2 |
| » Starters: Dave Roberts vs Chris Short | Sixth | 30½ out |
| Sunday, July 26 |
| » Defeated Phillies (45-51), 16-2 | Shibe Park (3-3) | 40-61 | |
| » Starters: Pat Dobson vs Rick Wise | Sixth | 30½ out |
| Tuesday, July 28 |
| » Lost to Expos (43-57), 5-4 | Parc Jarry (3-2) | 40-62 | |
| » Starters: Earl Wilson vs Steve Renko | Sixth | 30 out |
| Wednesday, July 29 |
| » Lost to Expos (44-57), 4-3 | Parc Jarry (3-3) | 40-63 | Lost 2 |
| » Starters: Clay Kirby vs Carl Morton | Sixth | 31 out |
| Friday, July 31 |
| » Lost to Mets (55-46), 6-5 | Shea Stadium (1-2) | 40-64 | Lost 3 |
| » Starters: Pat Dobson vs Gary Gentry | Sixth | 31 out |
| Saturday, August 1 |
| » Lost to Mets (56-46), 4-2 | Shea Stadium (1-3) | 40-65 | Lost 4 |
| » Starters: Earl Wilson vs Tom Seaver | Sixth | 32 out |
| Sunday, August 2 |
| » Defeated Mets (56-47), 3-0 | Shea Stadium (2-3) | 41-65 | |
| » Starters: Danny Coombs vs Jim McAndrew | Sixth | 31½ out |
| » Defeated Mets (56-48), 4-2 | Shea Stadium (3-3) | 42-65 | Won 2 |
| » Starters: Dave Roberts vs Ray Sadecki | Sixth | 31½ out |
| Monday, August 3 |
| » Defeated Reds (74-35), 10-3 | San Diego/Jack Murphy Stadium (21-31) | 43-65 | Won 3 |
| » Starters: Tony Cloninger vs Clay Kirby | Sixth | 30½ out |
| Tuesday, August 4 |
| » Lost to Reds (75-35), 12-1 | San Diego/Jack Murphy Stadium (21-32) | 43-66 | |
| » Starters: Jim Merritt vs Pat Dobson | Sixth | 31½ out |
| Wednesday, August 5 |
| » Lost to Astros (48-61), 4-3 | San Diego/Jack Murphy Stadium (21-33) | 43-67 | Lost 2 |
| » Starters: Don Wilson vs Earl Wilson | Sixth | 31½ out |
| Thursday, August 6 |
| » Lost to Astros (49-61), 8-6 | San Diego/Jack Murphy Stadium (21-34) | 43-68 | Lost 3 |
| » Starters: Jack Billingham vs Danny Coombs | Sixth | 31½ out |
| Friday, August 7 |
| » Lost to Braves (54-57), 8-2 | San Diego/Jack Murphy Stadium (21-35) | 43-69 | Lost 4 |
| » Starters: Phil Niekro vs Dave Roberts | Sixth | 32 out |
| » Defeated Braves (54-58), 6-1 | San Diego/Jack Murphy Stadium (22-35) | 44-69 | |
| » Starters: Ron Reed vs Clay Kirby | Sixth | 32 out |
| Sunday, August 9 |
| » Defeated Braves (54-59), 4-2 | San Diego/Jack Murphy Stadium (23-35) | 45-69 | Won 2 |
| » Starters: Pat Jarvis vs Pat Dobson | Sixth | 31 out |
| Tuesday, August 11 |
| » Lost to Cardinals (54-60), 11-10 | Busch Stadium II (2-2) | 45-70 | |
| » Starters: Earl Wilson vs Nelson Briles | Sixth | 32 out |
| Wednesday, August 12 |
| » Lost to Cardinals (55-60), 5-4 | Busch Stadium II (2-3) | 45-71 | Lost 2 |
| » Starters: Danny Coombs vs Bob Gibson | Sixth | 32 out |
| Thursday, August 13 |
| » Defeated Cardinals (55-61), 9-7 | Busch Stadium II (3-3) | 46-71 | |
| » Starters: Clay Kirby vs Reggie Cleveland | Sixth | 32 out |
| Friday, August 14 |
| » Lost to Pirates (65-53), 2-1 | Three Rivers Stadium (0-1) | 46-72 | |
| » Starters: Dave Roberts vs Steve Blass | Sixth | 32½ out |
| » Lost to Pirates (66-53), 10-1 | Three Rivers Stadium (0-2) | 46-73 | Lost 2 |
| » Starters: Pat Dobson vs Luke Walker | Sixth | 32½ out |
| Saturday, August 15 |
| » Lost to Pirates (67-53), 9-3 | Three Rivers Stadium (0-3) | 46-74 | Lost 3 |
| » Starters: Earl Wilson vs Bob Veale | Sixth | 33½ out |
| Sunday, August 16 |
| » Defeated Pirates (67-54), 8-6 | Three Rivers Stadium (1-3) | 47-74 | |
| » Starters: Danny Coombs vs Bruce DalCanton | Sixth | 33½ out |
| Monday, August 17 |
| » Lost to Cubs (63-59), 7-0 | Wrigley Field (1-3) | 47-75 | |
| » Starters: Clay Kirby vs Milt Pappas | Sixth | 34½ out |
| Tuesday, August 18 |
| » Defeated Cubs (63-60), 11-3 | Wrigley Field (2-3) | 48-75 | |
| » Starters: Pat Dobson vs Joe Decker | Fifth | 33½ out |
| Wednesday, August 19 |
| » Lost to Cubs (64-60), 12-2 | Wrigley Field (2-4) | 48-76 | |
| » Starters: Dave Roberts vs Fergie Jenkins | Fifth | 33½ out |
| Friday, August 21 |
| » Lost to Cardinals (58-66), 14-8 | San Diego/Jack Murphy Stadium (23-36) | 48-77 | Lost 2 |
| » Starters: Nelson Briles vs Earl Wilson | Sixth | 33½ out |
| Saturday, August 22 |
| » Lost to Cardinals (59-66), 7-0 | San Diego/Jack Murphy Stadium (23-37) | 48-78 | Lost 3 |
| » Starters: Bob Gibson vs Danny Coombs | Sixth | 34½ out |
| Sunday, August 23 |
| » Lost to Cardinals (60-66), 8-7 | San Diego/Jack Murphy Stadium (23-38) | 48-79 | Lost 4 |
| » Starters: Jerry Reuss vs Clay Kirby | Sixth | 35 out |
| Tuesday, August 25 |
| » Defeated Pirates (70-58), 4-3 | San Diego/Jack Murphy Stadium (24-38) | 49-79 | |
| » Starters: Luke Walker vs Dave Roberts | Sixth | 34 out |
| Wednesday, August 26 |
| » Defeated Pirates (70-59), 2-1 | San Diego/Jack Murphy Stadium (25-38) | 50-79 | Won 2 |
| » Starters: Fred Cambria vs Pat Dobson | Sixth | 34 out |
| Thursday, August 27 |
| » Lost to Cubs (67-64), 5-1 | San Diego/Jack Murphy Stadium (25-39) | 50-80 | |
| » Starters: Milt Pappas vs Earl Wilson | Sixth | 34 out |
| Friday, August 28 |
| » Lost to Cubs (68-64), 8-4 | San Diego/Jack Murphy Stadium (25-40) | 50-81 | Lost 2 |
| » Starters: Fergie Jenkins vs Clay Kirby | Sixth | 34 out |
| Sunday, August 30 |
| » Lost to Cubs (69-64), 3-0 | San Diego/Jack Murphy Stadium (25-41) | 50-82 | Lost 3 |
| » Starters: Bill Hands vs Dave Roberts | Sixth | 34½ out |
| Tuesday, September 1 |
| » Defeated Astros (62-71), 2-1 | Astrodome (1-6) | 51-82 | |
| » Starters: Pat Dobson vs Larry Dierker | Sixth | 33½ out |
| Wednesday, September 2 |
| » Lost to Astros (63-71), 2-1 | Astrodome (1-7) | 51-83 | |
| » Starters: Danny Coombs vs Wade Blasingame | Sixth | 34½ out |
| Thursday, September 3 |
| » Defeated Astros (63-72), 4-0 | Astrodome (2-7) | 52-83 | |
| » Starters: Clay Kirby vs Jack Billingham | Sixth | 34½ out |
| Friday, September 4 |
| » Defeated Reds (88-51), 15-2 | Riverfront Stadium (3-2) | 53-83 | Won 2 |
| » Starters: Mike Corkins vs Jim Merritt | Sixth | 33½ out |
| » Major-league debuts: Frank Duffy (Reds) |
| Future Padre Luis Lopez is born in Cidra, P.R. |
| Saturday, September 5 |
| » Lost to Reds (89-51), 6-2 | Riverfront Stadium (3-3) | 53-84 | |
| » Starters: Dave Roberts vs Milt Wilcox | Sixth | 34½ out |
| » Major-league debuts: Milt Wilcox (Reds) |
| Sunday, September 6 |
| » Lost to Reds (90-51), 6-5 | Riverfront Stadium (3-4) | 53-85 | Lost 2 |
| » Starters: Pat Dobson vs Jim McGlothlin | Sixth | 35½ out |
| Monday, September 7 |
| » Lost to Astros (66-73), 10-5 | San Diego/Jack Murphy Stadium (25-42) | 53-86 | Lost 3 |
| » Starters: Ken Forsch vs Jerry Nyman | Sixth | 35½ out |
| » Lost to Astros (67-73), 9-4 | San Diego/Jack Murphy Stadium (25-43) | 53-87 | Lost 4 |
| » Starters: Jack Billingham vs Danny Coombs | Sixth | 35½ out |
| » Major-league debuts: Ken Forsch (Astros) |
| Tuesday, September 8 |
| » Lost to Astros (68-73), 8-7 | San Diego/Jack Murphy Stadium (25-44) | 53-88 | Lost 5 |
| » Starters: Don Wilson vs Clay Kirby | Sixth | 36½ out |
| Wednesday, September 9 |
| » Lost to Braves (71-72), 6-3 | San Diego/Jack Murphy Stadium (25-45) | 53-89 | Lost 6 |
| » Starters: Mike McQueen vs Mike Corkins | Sixth | 37 out |
| » Defeated Braves (71-73), 7-4 | San Diego/Jack Murphy Stadium (26-45) | 54-89 | |
| » Starters: Phil Niekro vs Steve Arlin | Sixth | 37 out |
| Future Padre Joey Hamilton is born in Statesboro, GA. Future Padre Dan Miceli is born in Newark, NJ. |
| Thursday, September 10 |
| » Defeated Braves (71-74), 3-2 | San Diego/Jack Murphy Stadium (27-45) | 55-89 | Won 2 |
| » Starters: Ron Reed vs Dave Roberts | Sixth | 37 out |
| Friday, September 11 |
| » Defeated Reds (93-54), 3-2 | San Diego/Jack Murphy Stadium (28-45) | 56-89 | Won 3 |
| » Starters: Gary Nolan vs Pat Dobson | Sixth | 36 out |
| Saturday, September 12 |
| » Defeated Reds (93-55), 4-2 | San Diego/Jack Murphy Stadium (29-45) | 57-89 | Won 4 |
| » Starters: Tony Cloninger vs Danny Coombs | Sixth | 35 out |
| Sunday, September 13 |
| » Defeated Reds (93-56), 5-4 | San Diego/Jack Murphy Stadium (30-45) | 58-89 | Won 5 |
| » Starters: Wayne Simpson vs Clay Kirby | Sixth | 34 out |
| Monday, September 14 |
| » Lost to Dodgers (79-67), 12-4 | Dodger Stadium (2-5) | 58-90 | |
| » Starters: Jerry Nyman vs Claude Osteen | Sixth | 34½ out |
| Tuesday, September 15 |
| » Lost to Dodgers (80-67), 5-4 | Dodger Stadium (2-6) | 58-91 | Lost 2 |
| » Starters: Mike Corkins vs Don Sutton | Sixth | 34½ out |
| Wednesday, September 16 |
| » Defeated Dodgers (80-68), 4-0 | Dodger Stadium (3-6) | 59-91 | |
| » Starters: Dave Roberts vs Joe Moeller | Sixth | 34½ out |
| Thursday, September 17 |
| » Lost to Giants (80-70), 4-3 | San Diego/Jack Murphy Stadium (30-46) | 59-92 | |
| » Starters: Rich Robertson vs Pat Dobson | Sixth | 35 out |
| Friday, September 18 |
| » Lost to Giants (81-70), 3-2 | San Diego/Jack Murphy Stadium (30-47) | 59-93 | Lost 2 |
| » Starters: Frank Reberger vs Danny Coombs | Sixth | 36 out |
| Saturday, September 19 |
| » Lost to Giants (82-70), 3-0 | San Diego/Jack Murphy Stadium (30-48) | 59-94 | Lost 3 |
| » Starters: Gaylord Perry vs Clay Kirby | Sixth | 37 out |
| Tuesday, September 22 |
| » Lost to Braves (75-80), 3-2 | Atlanta-Fulton County Stadium (2-5) | 59-95 | Lost 4 |
| » Starters: Mike Corkins vs Jim Nash | Sixth | 38 out |
| Wednesday, September 23 |
| » Defeated Braves (75-81), 2-0 | Atlanta-Fulton County Stadium (3-5) | 60-95 | |
| » Starters: Steve Arlin vs Pat Jarvis | Fifth | 38 out |
| Thursday, September 24 |
| » Defeated Braves (75-82), 5-0 | Atlanta-Fulton County Stadium (4-5) | 61-95 | Won 2 |
| » Starters: Dave Roberts vs Mike McQueen | Fifth | 37½ out |
| Friday, September 25 |
| » Defeated Giants (84-72), 7-4 | Candlestick Park (3-4) | 62-95 | Won 3 |
| » Starters: Pat Dobson vs Frank Reberger | Sixth | 36½ out |
| Future Padre Ray Holbert is born in Torrance, CA. |
| Saturday, September 26 |
| » Lost to Giants (85-72), 7-6 | Candlestick Park (3-5) | 62-96 | |
| » Starters: Clay Kirby vs Juan Marichal | Fifth | 37½ out |
| Sunday, September 27 |
| » Lost to Giants (86-72), 3-2 | Candlestick Park (3-6) | 62-97 | Lost 2 |
| » Starters: Danny Coombs vs Gaylord Perry | Sixth | 38½ out |
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