| Monday, January 6 |
| Former Pirate Jim Viox dies in Erlanger, KY at the age of 79. |
| Friday, February 21 |
| Former Pirate Eddie Murphy dies in Dunmore, PA at the age of 78. |
| Sunday, February 23 |
| Former Pirate Bill Swift dies in Bartow, FL at the age of 62. |
| Friday, April 4 |
| Former Pirate Chuck Ward dies in Indian Rocks, FL at the age of 75. |
| Monday, April 7 |
| » Major-league debuts: Bob Didier (Braves) |
| Tuesday, April 8 |
| » Defeated Cardinals (0-1), 6-2 | Busch Stadium II (1-0) | 1-0 | |
| » W: Bruce Dal Canton (1-0) L: Mel Nelson (0-1) S: Chuck Hartenstein (1) | First | -- |
| Wednesday, April 9 |
| » Defeated Cardinals (0-2), 6-1 | Busch Stadium II (2-0) | 2-0 | Won 2 |
| » W: Bob Veale (1-0) L: Nelson Briles (0-1) | First | -- |
| Thursday, April 10 |
| » Defeated Cardinals (0-3), 3-2 | Busch Stadium II (3-0) | 3-0 | Won 3 |
| » W: Dock Ellis (1-0) L: Ray Washburn (0-1) | First | -- |
| Friday, April 11 |
| » Defeated Phillies (0-4), 7-1 | Forbes Field (1-0) | 4-0 | Won 4 |
| » W: Bob Moose (1-0) L: Jerry Johnson (0-1) | First | -- |
| Saturday, April 12 |
| » Lost to Phillies (1-4), 8-1 | Forbes Field (1-1) | 4-1 | |
| » W: Grant Jackson (1-0) L: Jim Bunning (0-1) | First | -- |
| Sunday, April 13 |
| » Defeated Phillies (1-5), 6-5 | Forbes Field (2-1) | 5-1 | |
| » W: Ron Kline (1-0) L: Bill Wilson (0-1) | First | -- |
| Monday, April 14 |
| » Lost to Cubs (6-1), 4-0 | Wrigley Field (0-1) | 5-2 | |
| » W: Ken Holtzman (2-0) L: Bob Veale (1-1) | Second | 1 out |
| Tuesday, April 15 |
| » Lost to Cubs (7-1), 7-4 | Wrigley Field (0-2) | 5-3 | Lost 2 |
| » W: Hank Aguirre (1-0) L: Dock Ellis (1-1) S: Ted Abernathy (1) | Second | 2 out |
| Wednesday, April 16 |
| » Defeated Mets (3-6), 11-3 | Forbes Field (3-1) | 6-3 | |
| » W: Bob Moose (2-0) L: Jerry Koosman (0-2) | Second | 2 out |
| Thursday, April 17 |
| » Defeated Mets (3-7), 4-0 | Forbes Field (4-1) | 7-3 | Won 2 |
| » W: Jim Bunning (1-1) L: Don Cardwell (0-2) S: Ron Kline (1) | Second | 2 out |
| Friday, April 18 |
| Future Pirate Angelo Encarnacion is born in Santo Domingo, D.R. |
| Saturday, April 19 |
| » Defeated Phillies (2-8), 8-6 | Shibe Park (1-0) | 8-3 | Won 3 |
| » W: Steve Blass (1-0) L: Grant Jackson (1-1) S: Bruce Dal Canton (1) | Second | 2 out |
| Former Pirate Harry Cassady dies in Fresno, CA at the age of 89. |
| Sunday, April 20 |
| » Lost to Phillies (3-8), 7-1 | Shibe Park (1-1) | 8-4 | |
| » W: Rick Wise (1-1) L: Bob Veale (1-2) S: Barry Lersch (1) | Second | 2½ out |
| Tuesday, April 22 |
| » Defeated Cubs (11-3), 7-5 | Forbes Field (5-1) | 9-4 | |
| » W: Chuck Hartenstein (1-0) L: Bill Hands (2-1) | Second | ½ out |
| » Defeated Cubs (11-4), 6-5 | Forbes Field (6-1) | 10-4 | Won 2 |
| » W: Bruce Dal Canton (2-0) L: Rich Nye (0-1) S: Ron Kline (2) | Second | ½ out |
| Wednesday, April 23 |
| » Lost to Mets (6-8), 2-0 | Shea Stadium (0-1) | 10-5 | |
| » W: Jerry Koosman (1-2) L: Jim Bunning (1-2) | Second | 1 out |
| Friday, April 25 |
| » Defeated Expos (6-10), 8-2 | Forbes Field (7-1) | 11-5 | |
| » W: Steve Blass (2-0) L: Carl Morton (0-2) S: Chuck Hartenstein (2) | Second | ½ out |
| Saturday, April 26 |
| » Defeated Expos (6-11), 4-3 | Forbes Field (8-1) | 12-5 | Won 2 |
| » W: Bob Veale (2-2) L: Bill Stoneman (2-3) S: Chuck Hartenstein (3) | Second | ½ out |
| Sunday, April 27 |
| » Lost to Expos (7-11), 4-2 | Forbes Field (8-2) | 12-6 | |
| » W: Larry Jaster (1-1) L: Dock Ellis (1-2) | Second | 1 out |
| Monday, April 28 |
| » Lost to Cardinals (8-11), 6-2 | Forbes Field (8-3) | 12-7 | Lost 2 |
| » W: Steve Carlton (2-2) L: Bob Moose (2-1) | Second | 2 out |
| Wednesday, April 30 |
| » Defeated Cardinals (8-12), 2-1 | Forbes Field (9-3) | 13-7 | |
| » W: Jim Bunning (2-2) L: Dave Giusti (2-2) | Second | 2 out |
| » Lost to Cardinals (9-12), 8-1 | Forbes Field (9-4) | 13-8 | |
| » W: Bob Gibson (2-2) L: Steve Blass (2-1) | Second | 2 out |
| Thursday, May 1 |
| » Lost to Cardinals (10-12), 9-3 | Forbes Field (9-5) | 13-9 | Lost 2 |
| » W: Nelson Briles (1-2) L: Bob Veale (2-3) | Second | 2½ out |
| Friday, May 2 |
| » Defeated Expos (8-14), 7-3 | Parc Jarry (1-0) | 14-9 | |
| » W: Dock Ellis (2-2) L: Larry Jaster (1-2) | Second | 2½ out |
| Saturday, May 3 |
| » Defeated Expos (8-15), 4-2 | Parc Jarry (2-0) | 15-9 | Won 2 |
| » W: Bob Moose (3-1) L: Carl Morton (0-3) S: Chuck Hartenstein (4) | Second | 2½ out |
| Sunday, May 4 |
| » Lost to Expos (9-15), 6-4 | Parc Jarry (2-1) | 15-10 | |
| » W: Roy Face (2-0) L: Ron Kline (1-1) | Second | 2 out |
| Tuesday, May 6 |
| » Lost to Padres (13-16), 4-2 | Forbes Field (9-6) | 15-11 | Lost 2 |
| » W: Dick Kelley (2-2) L: Steve Blass (2-2) S: Frank Reberger (4) | Second | 3 out |
| Wednesday, May 7 |
| » Defeated Padres (13-17), 2-0 | Forbes Field (10-6) | 16-11 | |
| » W: Bob Veale (3-3) L: Clay Kirby (1-4) S: Chuck Hartenstein (5) | Second | 2 out |
| Friday, May 9 |
| » Lost to Dodgers (17-11), 13-3 | Forbes Field (10-7) | 16-12 | |
| » W: Bill Singer (5-2) L: Dock Ellis (2-3) S: Joe Moeller (1) | Second | 2 out |
| Saturday, May 10 |
| » Lost to Dodgers (18-11), 4-1 | Forbes Field (10-8) | 16-13 | Lost 2 |
| » W: Don Sutton (4-3) L: Jim Bunning (2-3) S: Jim Brewer (4) | Second | 2½ out |
| Future Pirate Pete Schourek is born in Austin, TX. |
| Monday, May 12 |
| » Defeated Giants (17-13), 4-3 | Forbes Field (11-8) | 17-13 | |
| » W: Chuck Hartenstein (2-0) L: Joe Gibbon (1-1) | Second | 3 out |
| Tuesday, May 13 |
| » Lost to Giants (18-13), 11-8 | Forbes Field (11-9) | 17-14 | |
| » W: Ron Herbel (2-0) L: Bob Moose (3-2) S: Frank Linzy (4) | Second | 4 out |
| Wednesday, May 14 |
| » Lost to Giants (19-13), 3-0 | Forbes Field (11-10) | 17-15 | Lost 2 |
| » W: Juan Marichal (5-2) L: Jim Bunning (2-4) | Second | 5 out |
| Friday, May 16 |
| » Lost to Dodgers (19-13), 4-3 | Dodger Stadium (0-1) | 17-16 | Lost 3 |
| » W: Jim Brewer (2-1) L: Ron Kline (1-2) | Second | 6 out |
| Saturday, May 17 |
| » Lost to Dodgers (20-13), 6-0 | Dodger Stadium (0-2) | 17-17 | Lost 4 |
| » W: Claude Osteen (5-2) L: Dock Ellis (2-4) | Second | 6 out |
| Sunday, May 18 |
| » Lost to Dodgers (21-13), 6-5 | Dodger Stadium (0-3) | 17-18 | Lost 5 |
| » W: Jim Brewer (3-1) L: Pedro Ramos (0-1) | Second | 6 out |
| Monday, May 19 |
| Former Pirate Jim Tobin dies in Oakland, CA at the age of 57. |
| Tuesday, May 20 |
| » Defeated Padres (16-24), 6-3 | San Diego/Jack Murphy Stadium (1-0) | 18-18 | |
| » W: Jim Bunning (3-4) L: Joe Niekro (1-2) S: Chuck Hartenstein (6) | Second | 6 out |
| Wednesday, May 21 |
| » Defeated Padres (16-25), 11-1 | San Diego/Jack Murphy Stadium (2-0) | 19-18 | Won 2 |
| » W: Bob Moose (4-2) L: Tommie Sisk (0-3) | Second | 5 out |
| Thursday, May 22 |
| » Defeated Padres (16-26), 7-1 | San Diego/Jack Murphy Stadium (3-0) | 20-18 | Won 3 |
| » W: Steve Blass (3-2) L: Clay Kirby (1-6) | Second | 5 out |
| Friday, May 23 |
| » Lost to Giants (22-17), 3-0 | Candlestick Park (0-1) | 20-19 | |
| » W: Rich Robertson (1-0) L: Dock Ellis (2-5) | Second | 6 out |
| Saturday, May 24 |
| » Lost to Giants (23-17), 5-2 | Candlestick Park (0-2) | 20-20 | Lost 2 |
| » W: Mike McCormick (2-2) L: Bob Veale (3-4) | Second | 7 out |
| Sunday, May 25 |
| » Defeated Giants (23-18), 2-1 | Candlestick Park (1-2) | 21-20 | |
| » W: Jim Bunning (4-4) L: Gaylord Perry (7-4) | Second | 6 out |
| » Defeated Giants (23-19), 6-2 | Candlestick Park (2-2) | 22-20 | Won 2 |
| » W: Bob Moose (5-2) L: Ray Sadecki (2-5) S: Bruce Dal Canton (2) | Second | 6 out |
| Tuesday, May 27 |
| » Major-league debuts: Chuck Taylor (Cardinals) |
| Wednesday, May 28 |
| » Lost to Reds (21-19), 7-6 | Crosley Field (0-1) | 22-21 | |
| » W: Clay Carroll (5-3) L: Ron Kline (1-3) | Second | 6½ out |
| Former Pirate Gus Getz dies in Red Bank, NJ at the age of 80. |
| Thursday, May 29 |
| » Lost to Reds (22-19), 10-4 | Crosley Field (0-2) | 22-22 | Lost 2 |
| » W: Jim Merritt (5-2) L: Bob Veale (3-5) | Second | 7 out |
| Friday, May 30 |
| » Defeated Astros (23-25), 9-3 | Forbes Field (12-10) | 23-22 | |
| » W: Jim Bunning (5-4) L: Denny Lemaster (3-6) | Second | 7½ out |
| » Lost to Astros (24-25), 9-6 | Forbes Field (12-11) | 23-23 | |
| » W: Jack Billingham (4-2) L: Chuck Hartenstein (2-1) S: Fred Gladding (10) | Second | 7½ out |
| » Major-league debuts: Lou Marone (Pirates) |
| Saturday, May 31 |
| » Defeated Astros (24-26), 3-1 | Forbes Field (13-11) | 24-23 | |
| » W: Dock Ellis (3-5) L: Jim Ray (2-1) S: Ron Kline (3) | Second | 7½ out |
| Sunday, June 1 |
| » Defeated Astros (24-27), 14-7 | Forbes Field (14-11) | 25-23 | Won 2 |
| » W: Steve Blass (4-2) L: Don Wilson (5-5) | Second | 7½ out |
| Tuesday, June 3 |
| » Lost to Reds (25-20), 7-3 | Forbes Field (14-12) | 25-24 | |
| » W: Jim Merritt (6-2) L: Bob Veale (3-6) | Third | 8½ out |
| Wednesday, June 4 |
| » Lost to Reds (26-20), 5-3 | Forbes Field (14-13) | 25-25 | Lost 2 |
| » W: Clay Carroll (7-3) L: Chuck Hartenstein (2-2) S: Wayne Granger (5) | Third | 9½ out |
| Friday, June 6 |
| » Lost to Braves (30-19), 3-1 | Atlanta-Fulton County Stadium (0-1) | 25-26 | Lost 3 |
| » W: Phil Niekro (8-4) L: Dock Ellis (3-6) | Third | 10½ out |
| Saturday, June 7 |
| » Defeated Braves (30-20), 10-2 | Atlanta-Fulton County Stadium (1-1) | 26-26 | |
| » W: Steve Blass (5-2) L: Pat Jarvis (5-4) | Third | 10 out |
| Sunday, June 8 |
| » Lost to Braves (31-20), 11-10 | Atlanta-Fulton County Stadium (1-2) | 26-27 | |
| » W: Phil Niekro (9-4) L: Chuck Hartenstein (2-3) | Third | 11 out |
| » Lost to Braves (32-20), 4-3 | Atlanta-Fulton County Stadium (1-3) | 26-28 | Lost 2 |
| » W: Milt Pappas (4-5) L: Bob Veale (3-7) | Third | 11 out |
| Tuesday, June 10 |
| » Lost to Astros (28-30), 7-4 | Astrodome (0-1) | 26-29 | Lost 3 |
| » W: Tom Griffin (3-3) L: Dock Ellis (3-7) | Third | 11½ out |
| Wednesday, June 11 |
| » Defeated Astros (28-31), 13-8 | Astrodome (1-1) | 27-29 | |
| » W: Steve Blass (6-2) L: Skip Guinn (0-1) S: Chuck Hartenstein (7) | Third | 10½ out |
| Thursday, June 12 |
| » Defeated Astros (28-32), 4-3 | Astrodome (2-1) | 28-29 | Won 2 |
| » W: Jim Bunning (6-4) L: Fred Gladding (0-1) | Third | 10½ out |
| Friday, June 13 |
| » Defeated Braves (33-23), 2-1 | Forbes Field (15-13) | 29-29 | Won 3 |
| » W: Bruce Dal Canton (3-0) L: Milt Pappas (4-6) | Third | 10½ out |
| Saturday, June 14 |
| » Defeated Braves (33-24), 4-2 | Forbes Field (16-13) | 30-29 | Won 4 |
| » W: Bob Moose (6-2) L: Cecil Upshaw (1-2) | Third | 10½ out |
| » Major-league debuts: John Jeter (Pirates) |
| Sunday, June 15 |
| » Lost to Braves (34-24), 6-4 | Forbes Field (16-14) | 30-30 | |
| » W: Ron Reed (6-5) L: Steve Blass (6-3) S: Cecil Upshaw (13) | Third | 10½ out |
| Monday, June 16 |
| » Defeated Cubs (40-20), 9-8 | Forbes Field (17-14) | 31-30 | |
| » W: Bruce Dal Canton (4-0) L: Phil Regan (7-4) S: Steve Blass (1) | Third | 9½ out |
| Tuesday, June 17 |
| » Defeated Cubs (40-21), 1-0 | Forbes Field (18-14) | 32-30 | Won 2 |
| » W: Bob Veale (4-7) L: Fergie Jenkins (8-4) S: Bruce Dal Canton (3) | Third | 7½ out |
| » Defeated Cubs (40-22), 4-3 | Forbes Field (19-14) | 33-30 | Won 3 |
| » W: Steve Blass (7-3) L: Ted Abernathy (4-1) | Third | 7½ out |
| » Major-league debuts: Gene Garber (Pirates) |
| Wednesday, June 18 |
| » Defeated Cubs (40-23), 3-2 | Forbes Field (20-14) | 34-30 | Won 4 |
| » W: Joe Gibbon (2-3) L: Phil Regan (7-5) | Third | 6½ out |
| » Major-league debuts: Jose Martinez (Pirates) |
| Friday, June 20 |
| » Lost to Phillies (25-35), 8-7 | Shibe Park (1-2) | 34-31 | |
| » W: Bill Wilson (1-2) L: Lou Marone (0-1) S: John Boozer (2) | Third | 7½ out |
| Saturday, June 21 |
| » Defeated Phillies (25-36), 8-2 | Shibe Park (2-2) | 35-31 | |
| » W: Bruce Dal Canton (5-0) L: Lowell Palmer (0-1) | Third | 6½ out |
| » Major-league debuts: Lowell Palmer (Phillies) |
| Sunday, June 22 |
| » Defeated Phillies (25-37), 6-0 | Shibe Park (3-2) | 36-31 | Won 2 |
| » W: Dock Ellis (4-7) L: Bill Champion (1-3) | Third | 6½ out |
| » Lost to Phillies (26-37), 3-2 | Shibe Park (3-3) | 36-32 | |
| » W: Grant Jackson (7-6) L: Steve Blass (7-4) | Third | 6½ out |
| Monday, June 23 |
| » Lost to Cubs (43-25), 5-4 | Wrigley Field (0-3) | 36-33 | Lost 2 |
| » W: Phil Regan (8-5) L: Bruce Dal Canton (5-1) | Third | 7½ out |
| Tuesday, June 24 |
| » Lost to Cubs (44-25), 3-2 | Wrigley Field (0-4) | 36-34 | Lost 3 |
| » W: Bill Hands (7-6) L: Jim Bunning (6-5) | Third | 8½ out |
| Wednesday, June 25 |
| » Lost to Cubs (45-25), 5-2 | Wrigley Field (0-5) | 36-35 | Lost 4 |
| » W: Fergie Jenkins (9-5) L: Bob Veale (4-8) | Third | 9½ out |
| Thursday, June 26 |
| » Lost to Cubs (46-25), 7-5 | Wrigley Field (0-6) | 36-36 | Lost 5 |
| » W: Phil Regan (9-5) L: Bruce Dal Canton (5-2) | Third | 10½ out |
| Friday, June 27 |
| » Defeated Mets (38-31), 3-1 | Shea Stadium (1-1) | 37-36 | |
| » W: Steve Blass (8-4) L: Jerry Koosman (5-5) S: Joe Gibbon (3) | Third | 9½ out |
| Saturday, June 28 |
| » Defeated Mets (38-32), 7-4 | Shea Stadium (2-1) | 38-36 | Won 2 |
| » W: Jim Bunning (7-5) L: Gary Gentry (7-6) S: Joe Gibbon (4) | Third | 9½ out |
| Sunday, June 29 |
| » Lost to Mets (39-32), 7-3 | Shea Stadium (2-2) | 38-37 | |
| » W: Tom Seaver (12-3) L: Bob Veale (4-9) | Third | 11 out |
| Monday, June 30 |
| » Lost to Phillies (33-39), 4-2 | Forbes Field (20-15) | 38-38 | Lost 2 |
| » W: Woodie Fryman (7-4) L: Dock Ellis (4-8) S: John Boozer (5) | Third | 11 out |
| Tuesday, July 1 |
| » Lost to Phillies (34-39), 7-4 | Forbes Field (20-16) | 38-39 | Lost 3 |
| » W: Grant Jackson (9-6) L: Steve Blass (8-5) S: Bill Wilson (3) | Third | 11 out |
| Wednesday, July 2 |
| » Lost to Phillies (35-39), 14-4 | Forbes Field (20-17) | 38-40 | Lost 4 |
| » W: Al Raffo (1-2) L: Jim Bunning (7-6) S: John Boozer (6) | Third | 12 out |
| Friday, July 4 |
| » Lost to Mets (43-34), 11-6 | Forbes Field (20-18) | 38-41 | Lost 5 |
| » W: Tom Seaver (13-3) L: Bob Veale (4-10) | Third | 14 out |
| » Lost to Mets (44-34), 9-2 | Forbes Field (20-19) | 38-42 | Lost 6 |
| » W: Don Cardwell (3-8) L: Dock Ellis (4-9) | Third | 14 out |
| Sunday, July 6 |
| » Lost to Mets (45-34), 8-7 | Forbes Field (20-20) | 38-43 | Lost 7 |
| » W: Ron Taylor (4-2) L: Chuck Hartenstein (2-4) S: Cal Koonce (6) | Fourth | 13 out |
| Tuesday, July 8 |
| » Defeated Expos (26-56), 8-1 | Forbes Field (21-20) | 39-43 | |
| » W: Steve Blass (9-5) L: Mike Wegener (3-7) | Fourth | 12 out |
| Future Pirate Rosario Rodriguez is born in Los Mochis, Mexico. |
| Wednesday, July 9 |
| » Defeated Expos (26-57), 4-3 | Forbes Field (22-20) | 40-43 | Won 2 |
| » W: Joe Gibbon (3-3) L: Dick Radatz (2-3) | Third | 10½ out |
| » Defeated Expos (26-58), 3-2 | Forbes Field (23-20) | 41-43 | Won 3 |
| » W: Dock Ellis (5-9) L: Howie Reed (4-2) S: Joe Gibbon (5) | Third | 10½ out |
| Thursday, July 10 |
| » Defeated Expos (26-59), 2-1 | Forbes Field (24-20) | 42-43 | Won 4 |
| » W: Chuck Hartenstein (3-4) L: Dan McGinn (4-8) | Third | 10½ out |
| Friday, July 11 |
| » Lost to Cardinals (44-45), 6-1 | Busch Stadium II (3-1) | 42-44 | |
| » W: Steve Carlton (11-5) L: Luke Walker (0-1) | Fourth | 10½ out |
| Saturday, July 12 |
| » Lost to Cardinals (45-45), 6-3 | Busch Stadium II (3-2) | 42-45 | Lost 2 |
| » W: Ray Washburn (3-7) L: Steve Blass (9-6) | Fourth | 11½ out |
| Sunday, July 13 |
| » Defeated Cardinals (45-46), 3-0 | Busch Stadium II (4-2) | 43-45 | |
| » W: Jim Bunning (8-6) L: Bob Gibson (11-7) S: Bob Moose (1) | Fourth | 12½ out |
| » Lost to Cardinals (46-46), 4-2 | Busch Stadium II (4-3) | 43-46 | |
| » W: Nelson Briles (9-8) L: Dock Ellis (5-10) S: Joe Hoerner (11) | Fourth | 12½ out |
| Monday, July 14 |
| » Lost to Expos (28-61), 2-0 | Parc Jarry (2-2) | 43-47 | Lost 2 |
| » W: Bill Stoneman (5-12) L: Bob Veale (4-11) | Fourth | 13½ out |
| Tuesday, July 15 |
| » Defeated Expos (28-62), 9-3 | Parc Jarry (3-2) | 44-47 | |
| » W: Luke Walker (1-1) L: Gary Waslewski (1-3) | Fourth | 12½ out |
| Wednesday, July 16 |
| » Defeated Expos (28-63), 8-7 | Parc Jarry (4-2) | 45-47 | Won 2 |
| » W: Joe Gibbon (4-3) L: Dan McGinn (4-10) S: Chuck Hartenstein (8) | Fourth | 11½ out |
| Thursday, July 17 |
| » Lost to Expos (29-63), 5-4 | Parc Jarry (4-3) | 45-48 | |
| » W: Don Shaw (2-5) L: Jim Bunning (8-7) | Fourth | 12 out |
| Friday, July 18 |
| » Defeated Cardinals (49-47), 4-1 | Forbes Field (25-20) | 46-48 | |
| » W: Dock Ellis (6-10) L: Bob Gibson (11-8) | Fourth | 12 out |
| Saturday, July 19 |
| » Defeated Cardinals (49-48), 3-2 | Forbes Field (26-20) | 47-48 | Won 2 |
| » W: Bob Veale (5-11) L: Nelson Briles (9-9) S: Joe Gibbon (6) | Fourth | 11 out |
| Wednesday, July 23 |
| Former Pirate Roy Mahaffey dies in Anderson, SC at the age of 67. |
| Thursday, July 24 |
| » Defeated Padres (33-66), 4-3 | Forbes Field (27-20) | 48-48 | Won 3 |
| » W: Dock Ellis (7-10) L: Gary Ross (1-9) | Fourth | 12 out |
| Friday, July 25 |
| » Lost to Padres (34-66), 3-2 | Forbes Field (27-21) | 48-49 | |
| » W: Joe Niekro (6-6) L: Steve Blass (9-7) | Fourth | 12 out |
| Saturday, July 26 |
| » Defeated Padres (34-67), 4-3 | Forbes Field (28-21) | 49-49 | |
| » W: Bob Moose (7-2) L: Billy McCool (2-4) | Fourth | 12 out |
| Sunday, July 27 |
| » Defeated Padres (34-68), 4-1 | Forbes Field (29-21) | 50-49 | Won 2 |
| » W: Jim Bunning (9-7) L: Clay Kirby (3-13) S: Bob Moose (2) | Fourth | 11 out |
| Tuesday, July 29 |
| » Defeated Dodgers (55-44), 4-2 | Forbes Field (30-21) | 51-49 | Won 3 |
| » W: Joe Gibbon (5-3) L: Al McBean (2-5) | Fourth | 11 out |
| » Lost to Dodgers (56-44), 6-5 | Forbes Field (30-22) | 51-50 | |
| » W: Pete Mikkelsen (4-3) L: Dock Ellis (7-11) | Fourth | 11 out |
| Future Pirate Mike Williams is born in Radford, VA. |
| Wednesday, July 30 |
| » Defeated Dodgers (56-45), 4-2 | Forbes Field (31-22) | 52-50 | |
| » W: Steve Blass (10-7) L: Claude Osteen (13-9) | Fourth | 10 out |
| Thursday, July 31 |
| » Defeated Dodgers (56-46), 2-1 | Forbes Field (32-22) | 53-50 | Won 2 |
| » W: Chuck Hartenstein (4-4) L: Al McBean (2-6) | Fourth | 10 out |
| Friday, August 1 |
| » Lost to Giants (58-47), 5-1 | Forbes Field (32-23) | 53-51 | |
| » W: Mike McCormick (7-5) L: Jim Bunning (9-8) | Fourth | 11 out |
| Saturday, August 2 |
| » Defeated Giants (58-48), 7-3 | Forbes Field (33-23) | 54-51 | |
| » W: Bob Veale (6-11) L: Juan Marichal (13-7) | Fourth | 11 out |
| Sunday, August 3 |
| » Lost to Giants (59-48), 3-2 | Forbes Field (33-24) | 54-52 | |
| » W: Gaylord Perry (14-7) L: Dock Ellis (7-12) | Fourth | 12 out |
| Tuesday, August 5 |
| » Defeated Dodgers (57-50), 11-3 | Dodger Stadium (1-3) | 55-52 | |
| » W: Steve Blass (11-7) L: Alan Foster (3-6) | Fourth | 12½ out |
| Wednesday, August 6 |
| » Lost to Dodgers (58-50), 7-5 | Dodger Stadium (1-4) | 55-53 | |
| » W: Don Sutton (13-11) L: Luke Walker (1-2) S: Jim Brewer (17) | Fourth | 13½ out |
| Thursday, August 7 |
| » Lost to Dodgers (59-50), 6-0 | Dodger Stadium (1-5) | 55-54 | Lost 2 |
| » W: Claude Osteen (15-9) L: Jim Bunning (9-9) | Fourth | 14 out |
| Friday, August 8 |
| » Defeated Padres (35-77), 7-1 | San Diego/Jack Murphy Stadium (4-0) | 56-54 | |
| » W: Bob Veale (7-11) L: Joe Niekro (6-9) | Fourth | 13 out |
| Sunday, August 10 |
| » Defeated Padres (35-78), 7-5 | San Diego/Jack Murphy Stadium (5-0) | 57-54 | Won 2 |
| » W: Dock Ellis (8-12) L: Dick Kelley (4-8) S: Joe Gibbon (7) | Fourth | 12 out |
| » Defeated Padres (35-79), 8-6 | San Diego/Jack Murphy Stadium (6-0) | 58-54 | Won 3 |
| » W: Steve Blass (12-7) L: Clay Kirby (3-15) S: Joe Gibbon (8) | Fourth | 12 out |
| Tuesday, August 12 |
| » Lost to Giants (62-52), 6-3 | Candlestick Park (2-3) | 58-55 | |
| » W: Gaylord Perry (15-8) L: Luke Walker (1-3) | Fourth | 13 out |
| Wednesday, August 13 |
| » Defeated Giants (62-53), 10-5 | Candlestick Park (3-3) | 59-55 | |
| » W: Jim Bunning (10-9) L: Mike McCormick (8-7) S: Bob Moose (3) | Fourth | 13 out |
| Friday, August 15 |
| » Defeated Reds (63-49), 5-1 | Crosley Field (1-2) | 60-55 | Won 2 |
| » W: Bob Veale (8-11) L: Gary Nolan (3-4) | Fourth | 12 out |
| Saturday, August 16 |
| » Lost to Reds (64-49), 5-2 | Crosley Field (1-3) | 60-56 | |
| » W: Jim Merritt (13-5) L: Dock Ellis (8-13) | Fourth | 13 out |
| Sunday, August 17 |
| » Defeated Reds (64-50), 8-5 | Crosley Field (2-3) | 61-56 | |
| » W: Steve Blass (13-7) L: Jack Fisher (3-3) S: Chuck Hartenstein (9) | Fourth | 12½ out |
| Monday, August 18 |
| » Defeated Reds (64-51), 12-5 | Crosley Field (3-3) | 62-56 | Won 2 |
| » W: Bruce Dal Canton (6-2) L: Wayne Granger (7-5) | Fourth | 12 out |
| Tuesday, August 19 |
| » Defeated Astros (64-56), 5-1 | Forbes Field (34-24) | 63-56 | Won 3 |
| » W: Luke Walker (2-3) L: Don Wilson (15-8) S: Joe Gibbon (9) | Fourth | 12 out |
| Wednesday, August 20 |
| » Defeated Astros (64-57), 1-0 | Forbes Field (35-24) | 64-56 | Won 4 |
| » W: Bob Veale (9-11) L: Denny Lemaster (9-13) | Fourth | 11 out |
| Friday, August 22 |
| » Defeated Reds (66-53), 8-2 | Forbes Field (36-24) | 65-56 | Won 5 |
| » W: Dock Ellis (9-13) L: Jack Fisher (3-4) | Fourth | 9 out |
| » Defeated Reds (66-54), 5-3 | Forbes Field (37-24) | 66-56 | Won 6 |
| » W: Bruce Dal Canton (7-2) L: Clay Carroll (12-6) | Fourth | 9 out |
| Saturday, August 23 |
| » Defeated Reds (66-55), 3-1 | Forbes Field (38-24) | 67-56 | Won 7 |
| » W: Bob Moose (8-2) L: Gerry Arrigo (2-4) S: Chuck Hartenstein (10) | Fourth | 9 out |
| Sunday, August 24 |
| » Defeated Reds (66-56), 9-4 | Forbes Field (39-24) | 68-56 | Won 8 |
| » W: Bob Veale (10-11) L: Jim Maloney (6-4) S: Bruce Dal Canton (4) | Fourth | 8½ out |
| Tuesday, August 26 |
| » Lost to Braves (71-59), 6-4 | Forbes Field (39-25) | 68-57 | |
| » W: Ron Reed (13-8) L: Luke Walker (2-4) S: Paul Doyle (3) | Fourth | 8 out |
| Wednesday, August 27 |
| » Lost to Braves (72-59), 1-0 | Forbes Field (39-26) | 68-58 | Lost 2 |
| » W: Phil Niekro (18-11) L: Dock Ellis (9-14) | Fourth | 8 out |
| Thursday, August 28 |
| » Lost to Braves (73-59), 8-2 | Forbes Field (39-27) | 68-59 | Lost 3 |
| » W: George Stone (11-8) L: Steve Blass (13-8) S: Paul Doyle (4) | Fourth | 9 out |
| Friday, August 29 |
| » Defeated Astros (68-62), 4-2 | Astrodome (3-1) | 69-59 | |
| » W: Bob Moose (9-2) L: Jim Bouton (2-2) | Fourth | 9 out |
| Saturday, August 30 |
| » Lost to Astros (69-62), 2-1 | Astrodome (3-2) | 69-60 | |
| » W: Larry Dierker (17-10) L: Bo Belinsky (0-1) | Fourth | 10 out |
| Sunday, August 31 |
| » Defeated Astros (69-63), 6-4 | Astrodome (4-2) | 70-60 | |
| » W: Lou Marone (1-1) L: Fred Gladding (2-6) S: Steve Blass (2) | Third | 10 out |
| Monday, September 1 |
| » Defeated Braves (73-63), 7-1 | Atlanta-Fulton County Stadium (2-3) | 71-60 | Won 2 |
| » W: Bob Moose (10-2) L: Jim Britton (7-5) | Third | 9½ out |
| Wednesday, September 3 |
| » Lost to Braves (74-63), 8-1 | Atlanta-Fulton County Stadium (2-4) | 71-61 | |
| » W: Ron Reed (14-9) L: Dock Ellis (9-15) S: Cecil Upshaw (23) | Third | 10½ out |
| » Major-league debuts: Oscar Brown (Braves) |
| Friday, September 5 |
| » Defeated Cubs (84-54), 9-2 | Wrigley Field (1-6) | 72-61 | |
| » W: Steve Blass (14-8) L: Ken Holtzman (16-9) | Third | 9½ out |
| Saturday, September 6 |
| » Defeated Cubs (84-55), 13-4 | Wrigley Field (2-6) | 73-61 | Won 2 |
| » W: Bob Veale (11-11) L: Fergie Jenkins (19-12) | Third | 8½ out |
| Sunday, September 7 |
| » Defeated Cubs (84-56), 7-5 | Wrigley Field (3-6) | 74-61 | Won 3 |
| » W: Bruce Dal Canton (8-2) L: Ken Johnson (2-5) | Third | 7½ out |
| Monday, September 8 |
| » Defeated Expos (43-97), 6-2 | Parc Jarry (5-3) | 75-61 | Won 4 |
| » W: Chuck Hartenstein (5-4) L: Claude Raymond (3-4) S: Bruce Dal Canton (5) | Third | 6½ out |
| Tuesday, September 9 |
| » Lost to Expos (44-97), 4-2 | Parc Jarry (5-4) | 75-62 | |
| » W: Steve Renko (4-6) L: Luke Walker (2-5) | Third | 6½ out |
| Wednesday, September 10 |
| » Lost to Cardinals (76-65), 11-2 | Forbes Field (39-28) | 75-63 | Lost 2 |
| » W: Bob Gibson (17-11) L: Steve Blass (14-9) | Fourth | 8 out |
| » Lost to Cardinals (77-65), 2-1 | Forbes Field (39-29) | 75-64 | Lost 3 |
| » W: Mike Torrez (8-4) L: Bo Belinsky (0-2) S: Mudcat Grant (6) | Fourth | 8 out |
| Former Pirate Jap Barbeau dies in Milwaukee, WI at the age of 88. |
| Thursday, September 11 |
| » Defeated Cardinals (77-66), 3-2 | Forbes Field (40-29) | 76-64 | |
| » W: Bob Veale (12-11) L: Steve Carlton (16-9) | Third | 8 out |
| Friday, September 12 |
| » Lost to Mets (86-57), 1-0 | Forbes Field (40-30) | 76-65 | |
| » W: Jerry Koosman (14-9) L: Bob Moose (10-3) | Fourth | 10 out |
| » Lost to Mets (87-57), 1-0 | Forbes Field (40-31) | 76-66 | Lost 2 |
| » W: Don Cardwell (7-9) L: Dock Ellis (9-16) S: Tug McGraw (12) | Fourth | 10 out |
| Saturday, September 13 |
| » Lost to Mets (88-57), 5-2 | Forbes Field (40-32) | 76-67 | Lost 3 |
| » W: Tom Seaver (22-7) L: Luke Walker (2-6) | Fourth | 11 out |
| » Major-league debuts: Dave Cash (Pirates) |
| Sunday, September 14 |
| » Defeated Mets (88-58), 5-3 | Forbes Field (41-32) | 77-67 | |
| » W: Steve Blass (15-9) L: Nolan Ryan (6-2) | Fourth | 10 out |
| Monday, September 15 |
| » Lost to Phillies (58-87), 2-1 | Shibe Park (3-4) | 77-68 | |
| » W: Rick Wise (14-11) L: Bob Veale (12-12) | Fourth | 11½ out |
| » Lost to Phillies (59-87), 4-3 | Shibe Park (3-5) | 77-69 | Lost 2 |
| » W: Jeff James (2-0) L: Bo Belinsky (0-3) | Fourth | 11½ out |
| » Major-league debuts: Angel Mangual (Pirates) |
| Tuesday, September 16 |
| » Defeated Phillies (59-88), 9-5 | Shibe Park (4-5) | 78-69 | |
| » W: Bob Moose (11-3) L: Woodie Fryman (11-14) S: Joe Gibbon (10) | Fourth | 11 out |
| Wednesday, September 17 |
| » Defeated Cardinals (79-69), 4-2 | Busch Stadium II (5-3) | 79-69 | Won 2 |
| » W: Dock Ellis (10-16) L: Chuck Taylor (7-4) | Third | 11 out |
| Thursday, September 18 |
| » Lost to Cardinals (80-69), 8-7 | Busch Stadium II (5-4) | 79-70 | |
| » W: Sal Campisi (1-0) L: Joe Gibbon (5-4) | Fourth | 12 out |
| Friday, September 19 |
| » Defeated Mets (91-59), 8-2 | Shea Stadium (3-2 |