| Wednesday, January 15 |
| Future Oriole Delino DeShields is born in Seaford, DE. |
| Saturday, January 18 |
| Future Oriole Kevin McGehee is born in Alexandria, LA. |
| Saturday, February 15 |
| Future Oriole Brian Williams is born in Lancaster, SC. |
| Monday, April 7 |
| » Major-league debuts: Bob Didier (Braves) |
| Future Oriole Ricky Bones is born in Salinas, P.R. |
| Tuesday, April 8 |
| » Lost to Red Sox (1-0), 5-4 | Memorial Stadium (0-1) | 0-1 | |
| » W: Bill Landis (1-0) L: Mike Adamson (0-1) S: Juan Pizarro (1) | Second | 1 out |
| Thursday, April 10 |
| » Defeated Red Sox (1-1), 2-1 | Memorial Stadium (1-1) | 1-1 | |
| » W: Dave Leonhard (1-0) L: Juan Pizarro (0-1) | Third | 1 out |
| Friday, April 11 |
| » Lost to Senators (3-1), 4-0 | Memorial Stadium (1-2) | 1-2 | |
| » W: Barry Moore (1-0) L: Jim Hardin (0-1) S: Dennis Higgins (2) | Fourth | 1½ out |
| Saturday, April 12 |
| » Defeated Senators (3-2), 9-0 | Memorial Stadium (2-2) | 2-2 | |
| » W: Dave McNally (1-0) L: Camilo Pascual (0-2) | Third | 1 out |
| Sunday, April 13 |
| » Defeated Senators (3-3), 2-0 | Memorial Stadium (3-2) | 3-2 | Won 2 |
| » W: Jim Palmer (1-0) L: Joe Coleman (1-1) | Second | ½ out |
| » Defeated Senators (3-4), 9-0 | Memorial Stadium (4-2) | 4-2 | Won 3 |
| » W: Tom Phoebus (1-0) L: Dick Bosman (0-1) | Second | ½ out |
| Monday, April 14 |
| » Lost to Red Sox (5-1), 5-3 | Fenway Park (0-1) | 4-3 | |
| » W: Ray Culp (1-0) L: Mike Cuellar (0-1) S: Sparky Lyle (1) | Third | 1½ out |
| Future Oriole Brad Pennington is born in Salem, IN. |
| Tuesday, April 15 |
| » Defeated Red Sox (5-2), 10-5 | Fenway Park (1-1) | 5-3 | |
| » W: Pete Richert (1-0) L: Bill Landis (3-1) | Second | ½ out |
| » Major-league debuts: Ray Jarvis and Syd O'Brien (Red Sox) |
| Wednesday, April 16 |
| » Defeated Red Sox (5-3), 11-8 | Fenway Park (2-1) | 6-3 | Won 2 |
| » W: Dave Leonhard (2-0) L: Ken Brett (0-1) S: Dick Hall (1) | First | -- |
| Thursday, April 17 |
| » Defeated Red Sox (5-4), 9-5 | Fenway Park (3-1) | 7-3 | Won 3 |
| » W: Jim Palmer (2-0) L: Lee Stange (1-1) S: Eddie Watt (1) | First | -- |
| Friday, April 18 |
| » Defeated Senators (4-7), 6-0 | Robert F. Kennedy Stadium (1-0) | 8-3 | Won 4 |
| » W: Tom Phoebus (2-0) L: Joe Coleman (1-2) | First | -- |
| Saturday, April 19 |
| » Lost to Senators (5-7), 7-5 | Robert F. Kennedy Stadium (1-1) | 8-4 | |
| » W: Dick Bosman (1-1) L: Mike Cuellar (0-2) S: Dennis Higgins (4) | First | -- |
| Sunday, April 20 |
| » Defeated Senators (5-8), 2-1 | Robert F. Kennedy Stadium (2-1) | 9-4 | |
| » W: Dave McNally (2-0) L: Jim Hannan (1-1) S: Eddie Watt (2) | First | -- |
| » Lost to Senators (6-8), 5-2 | Robert F. Kennedy Stadium (2-2) | 9-5 | |
| » W: Frank Bertaina (1-1) L: Jim Hardin (0-2) S: Bob Humphreys (1) | First | -- |
| Monday, April 21 |
| » Defeated Indians (1-10), 11-0 | Memorial Stadium (5-2) | 10-5 | |
| » W: Jim Palmer (3-0) L: Sam McDowell (0-2) | First | -- |
| Tuesday, April 22 |
| » Defeated Indians (1-11), 3-2 | Memorial Stadium (6-2) | 11-5 | Won 2 |
| » W: Tom Phoebus (3-0) L: Stan Williams (0-2) S: Pete Richert (1) | First | -- |
| Wednesday, April 23 |
| » Defeated Tigers (8-5), 3-2 | Memorial Stadium (7-2) | 12-5 | Won 3 |
| » W: Mike Cuellar (1-2) L: Denny McLain (2-3) | First | -- |
| Thursday, April 24 |
| » Defeated Tigers (8-6), 5-2 | Memorial Stadium (8-2) | 13-5 | Won 4 |
| » W: Dave McNally (3-0) L: Earl Wilson (1-2) | First | -- |
| Friday, April 25 |
| » Lost to Yankees (9-6), 7-2 | Memorial Stadium (8-3) | 13-6 | |
| » W: Mel Stottlemyre (5-0) L: Jim Hardin (0-3) | First | -- |
| Saturday, April 26 |
| » Lost to Yankees (10-6), 6-5 | Memorial Stadium (8-4) | 13-7 | Lost 2 |
| » W: Lindy McDaniel (2-0) L: Pete Richert (1-1) | First | -- |
| Sunday, April 27 |
| » Defeated Yankees (10-7), 6-0 | Memorial Stadium (9-4) | 14-7 | |
| » W: Mike Cuellar (2-2) L: Stan Bahnsen (0-5) | First | -- |
| » Defeated Yankees (10-8), 10-5 | Memorial Stadium (10-4) | 15-7 | Won 2 |
| » W: Dick Hall (1-0) L: Lindy McDaniel (2-1) | First | -- |
| Monday, April 28 |
| Future Oriole Jimmy Myers is born in Oklahoma City, OK. |
| Wednesday, April 30 |
| » Defeated Tigers (10-10), 3-2 | Tiger Stadium (1-0) | 16-7 | Won 3 |
| » W: Dave McNally (4-0) L: Pat Dobson (0-2) S: Pete Richert (2) | First | -- |
| Thursday, May 1 |
| » Lost to Tigers (11-10), 2-0 | Tiger Stadium (1-1) | 16-8 | |
| » W: Denny McLain (4-3) L: Jim Palmer (3-1) | First | -- |
| Friday, May 2 |
| » Defeated Yankees (11-12), 5-1 | Yankee Stadium (1-0) | 17-8 | |
| » W: Mike Cuellar (3-2) L: Fritz Peterson (3-3) | First | -- |
| Saturday, May 3 |
| » Defeated Yankees (11-13), 5-4 | Yankee Stadium (2-0) | 18-8 | Won 2 |
| » W: Dick Hall (2-0) L: Lindy McDaniel (2-2) | First | -- |
| Sunday, May 4 |
| » Defeated Yankees (11-14), 5-3 | Yankee Stadium (3-0) | 19-8 | Won 3 |
| » W: Dave McNally (5-0) L: Bill Burbach (1-2) S: Pete Richert (3) | First | -- |
| » Defeated Yankees (11-15), 14-2 | Yankee Stadium (4-0) | 20-8 | Won 4 |
| » W: Jim Hardin (1-3) L: Mike Kekich (0-1) | First | -- |
| Tuesday, May 6 |
| » Lost to White Sox (9-11), 1-0 | Memorial Stadium (10-5) | 20-9 | |
| » W: Joe Horlen (3-2) L: Jim Palmer (3-2) | First | -- |
| Wednesday, May 7 |
| » Lost to White Sox (10-11), 6-4 | Memorial Stadium (10-6) | 20-10 | Lost 2 |
| » W: Gary Peters (2-4) L: Mike Cuellar (3-3) S: Bob Locker (3) | First | -- |
| Friday, May 9 |
| » Lost to Royals (15-12), 4-2 | Memorial Stadium (10-7) | 20-11 | Lost 3 |
| » W: Dick Drago (2-0) L: Dick Hall (2-1) | First | -- |
| Saturday, May 10 |
| » Defeated Royals (15-13), 6-5 | Memorial Stadium (11-7) | 21-11 | |
| » W: Jim Hardin (2-3) L: Moe Drabowsky (3-2) | First | -- |
| Sunday, May 11 |
| » Defeated Royals (15-14), 5-0 | Memorial Stadium (12-7) | 22-11 | Won 2 |
| » W: Jim Palmer (4-2) L: Roger Nelson (2-3) | First | -- |
| Tuesday, May 13 |
| » Lost to Twins (19-9), 4-2 | Metropolitan Stadium (0-1) | 22-12 | |
| » W: Dave Boswell (4-3) L: Mike Cuellar (3-4) S: Ron Perranoski (7) | First | -- |
| Future Oriole Lyle Mouton is born in Lafayette, LA. |
| Wednesday, May 14 |
| » Defeated Twins (19-10), 9-8 | Metropolitan Stadium (1-1) | 23-12 | |
| » W: Tom Phoebus (4-0) L: Dick Woodson (1-1) S: Eddie Watt (3) | First | -- |
| Thursday, May 15 |
| » Defeated Twins (19-11), 5-0 | Metropolitan Stadium (2-1) | 24-12 | Won 2 |
| » W: Dave McNally (6-0) L: Jim Kaat (2-2) | First | -- |
| Friday, May 16 |
| » Defeated Royals (16-17), 5-3 | Municipal Stadium (1-0) | 25-12 | Won 3 |
| » W: Eddie Watt (1-0) L: Steve Jones (2-2) | First | -- |
| Saturday, May 17 |
| » Defeated Royals (16-18), 4-2 | Municipal Stadium (2-0) | 26-12 | Won 4 |
| » W: Jim Palmer (5-2) L: Bill Butler (1-2) | First | -- |
| Sunday, May 18 |
| » Defeated Royals (16-19), 5-0 | Municipal Stadium (3-0) | 27-12 | Won 5 |
| » W: Mike Cuellar (4-4) L: Dick Drago (2-1) | First | -- |
| Tuesday, May 20 |
| » Lost to Twins (20-13), 3-2 | Memorial Stadium (12-8) | 27-13 | |
| » W: Jim Kaat (3-2) L: Marcelino Lopez (0-1) S: Ron Perranoski (8) | First | -- |
| Wednesday, May 21 |
| » Defeated Twins (20-14), 4-3 | Memorial Stadium (13-8) | 28-13 | |
| » W: Tom Phoebus (5-0) L: Dave Boswell (4-5) S: Pete Richert (4) | First | -- |
| » Major-league debuts: Jerry Crider (Twins) |
| Thursday, May 22 |
| » Defeated Twins (20-15), 6-2 | Memorial Stadium (14-8) | 29-13 | Won 2 |
| » W: Dick Hall (3-1) L: Ron Perranoski (3-2) S: Eddie Watt (4) | First | -- |
| Friday, May 23 |
| » Defeated Athletics (21-15), 4-3 | Memorial Stadium (15-8) | 30-13 | Won 3 |
| » W: Dave Leonhard (3-0) L: Blue Moon Odom (7-2) | First | -- |
| Saturday, May 24 |
| » Defeated Athletics (21-16), 2-1 | Memorial Stadium (16-8) | 31-13 | Won 4 |
| » W: Mike Cuellar (5-4) L: Catfish Hunter (3-4) | First | -- |
| Sunday, May 25 |
| » Defeated Athletics (21-17), 5-3 | Memorial Stadium (17-8) | 32-13 | Won 5 |
| » W: Marcelino Lopez (1-1) L: Lew Krausse (0-2) S: Eddie Watt (5) | First | -- |
| Monday, May 26 |
| Future Oriole John O'Donoghue is born in Wilmington, DE. |
| Tuesday, May 27 |
| » Lost to Pilots (20-21), 8-1 | Sick's Stadium (0-1) | 32-14 | |
| » W: Gene Brabender (2-3) L: Tom Phoebus (5-1) | First | -- |
| Former Oriole Lou Jackson dies in Tokyo, Japan at the age of 34. |
| Wednesday, May 28 |
| » Defeated Pilots (20-22), 9-5 | Sick's Stadium (1-1) | 33-14 | |
| » W: Dave McNally (7-0) L: Mike Marshall (3-6) S: Pete Richert (5) | First | -- |
| Friday, May 30 |
| » Defeated Angels (13-29), 3-1 | Anaheim Stadium (1-0) | 34-14 | Won 2 |
| » W: Mike Cuellar (6-4) L: Andy Messersmith (0-5) | First | -- |
| Saturday, May 31 |
| » Lost to Angels (14-29), 4-3 | Anaheim Stadium (1-1) | 34-15 | |
| » W: Ken Tatum (1-0) L: Eddie Watt (1-1) | First | -- |
| Sunday, June 1 |
| » Defeated Angels (14-30), 4-3 | Anaheim Stadium (2-1) | 35-15 | |
| » W: Jim Palmer (6-2) L: Bob Priddy (0-1) | First | -- |
| Tuesday, June 3 |
| » Defeated Athletics (24-22), 3-1 | Oakland-Alameda County Stadium (1-0) | 36-15 | Won 2 |
| » W: Eddie Watt (2-1) L: Lew Krausse (0-3) | First | -- |
| Wednesday, June 4 |
| » Defeated Athletics (24-23), 6-1 | Oakland-Alameda County Stadium (2-0) | 37-15 | Won 3 |
| » W: Tom Phoebus (6-1) L: Catfish Hunter (3-6) | First | -- |
| Friday, June 6 |
| » Defeated Pilots (22-27), 5-1 | Memorial Stadium (18-8) | 38-15 | Won 4 |
| » W: Dave McNally (8-0) L: Gary Bell (2-6) | First | -- |
| Saturday, June 7 |
| » Defeated Pilots (22-28), 10-0 | Memorial Stadium (19-8) | 39-15 | Won 5 |
| » W: Jim Palmer (7-2) L: Gene Brabender (2-4) | First | -- |
| Sunday, June 8 |
| » Lost to Pilots (23-28), 7-5 | Memorial Stadium (19-9) | 39-16 | |
| » W: John O'Donoghue (1-0) L: Mike Cuellar (6-5) | First | -- |
| Tuesday, June 10 |
| » Defeated Angels (17-35), 11-4 | Memorial Stadium (20-9) | 40-16 | |
| » W: Marcelino Lopez (2-1) L: Rudy May (2-7) | First | -- |
| Wednesday, June 11 |
| » Lost to Angels (18-35), 7-5 | Memorial Stadium (20-10) | 40-17 | |
| » W: Pedro Borbon (2-1) L: Pete Richert (1-2) S: Eddie Fisher (1) | First | -- |
| Friday, June 13 |
| » Defeated White Sox (23-29), 5-2 | Comiskey Park I (1-0) | 41-17 | |
| » W: Dave Leonhard (4-0) L: Gary Peters (4-8) | First | -- |
| Saturday, June 14 |
| » Defeated White Sox (23-30), 12-3 | Comiskey Park I (2-0) | 42-17 | Won 2 |
| » W: Jim Palmer (8-2) L: Tommy John (4-5) S: Eddie Watt (6) | First | -- |
| Sunday, June 15 |
| » Defeated White Sox (23-31), 9-0 | Comiskey Park I (3-0) | 43-17 | Won 3 |
| » W: Dave McNally (9-0) L: Jerry Nyman (2-3) | First | -- |
| » Defeated White Sox (23-32), 13-2 | Comiskey Park I (4-0) | 44-17 | Won 4 |
| » W: Tom Phoebus (7-1) L: Joe Horlen (4-6) | First | -- |
| Tuesday, June 17 |
| » Defeated Senators (31-33), 5-1 | Robert F. Kennedy Stadium (3-2) | 45-17 | Won 5 |
| » W: Mike Cuellar (7-5) L: Jim Shellenback (1-2) | First | -- |
| Wednesday, June 18 |
| » Defeated Senators (31-34), 3-1 | Robert F. Kennedy Stadium (4-2) | 46-17 | Won 6 |
| » W: Jim Hardin (3-3) L: Barry Moore (5-2) S: Dick Hall (2) | First | -- |
| Thursday, June 19 |
| » Defeated Senators (31-35), 2-0 | Robert F. Kennedy Stadium (5-2) | 47-17 | Won 7 |
| » W: Dave McNally (10-0) L: Dennis Higgins (4-7) | First | -- |
| Friday, June 20 |
| » Lost to Indians (23-37), 7-2 | Cleveland Stadium (0-1) | 47-18 | |
| » W: Luis Tiant (4-8) L: Tom Phoebus (7-2) | First | -- |
| » Defeated Indians (23-38), 5-1 | Cleveland Stadium (1-1) | 48-18 | |
| » W: Marcelino Lopez (3-1) L: Steve Hargan (1-4) S: Eddie Watt (7) | First | -- |
| Saturday, June 21 |
| » Defeated Indians (23-39), 3-1 | Cleveland Stadium (2-1) | 49-18 | Won 2 |
| » W: Mike Cuellar (8-5) L: Stan Williams (2-7) | First | -- |
| Sunday, June 22 |
| » Lost to Indians (24-39), 3-2 | Cleveland Stadium (2-2) | 49-19 | |
| » W: Sam McDowell (9-6) L: Dick Hall (3-2) | First | -- |
| » Defeated Indians (24-40), 6-0 | Cleveland Stadium (3-2) | 50-19 | |
| » W: Dave Leonhard (5-0) L: Horacio Pina (2-2) | First | -- |
| Monday, June 23 |
| » Defeated Senators (34-37), 5-3 | Memorial Stadium (21-10) | 51-19 | Won 2 |
| » W: Jim Palmer (9-2) L: Darold Knowles (3-1) S: Pete Richert (6) | First | -- |
| Tuesday, June 24 |
| » Defeated Senators (34-38), 6-3 | Memorial Stadium (22-10) | 52-19 | Won 3 |
| » W: Dick Hall (4-2) L: Jim Shellenback (1-3) | First | -- |
| Wednesday, June 25 |
| » Lost to Senators (35-38), 11-8 | Memorial Stadium (22-11) | 52-20 | |
| » W: Bob Humphreys (2-2) L: Jim Hardin (3-4) S: Darold Knowles (2) | First | -- |
| Friday, June 27 |
| » Defeated Tigers (38-30), 4-1 | Memorial Stadium (23-11) | 53-20 | |
| » W: Dave McNally (11-0) L: Earl Wilson (6-7) | First | -- |
| Saturday, June 28 |
| » Defeated Tigers (38-31), 6-4 | Memorial Stadium (24-11) | 54-20 | Won 2 |
| » W: Pete Richert (2-2) L: Daryl Patterson (0-1) S: Eddie Watt (8) | First | -- |
| Sunday, June 29 |
| » Lost to Tigers (39-31), 3-2 | Memorial Stadium (24-12) | 54-21 | |
| » W: Mickey Lolich (10-1) L: Mike Cuellar (8-6) S: Mike Kilkenny (1) | First | -- |
| » Defeated Tigers (39-32), 4-3 | Memorial Stadium (25-12) | 55-21 | |
| » W: Dave Leonhard (6-0) L: Don McMahon (1-5) | First | -- |
| Tuesday, July 1 |
| » Lost to Yankees (37-42), 10-9 | Yankee Stadium (4-1) | 55-22 | |
| » W: Jack Aker (4-2) L: Pete Richert (2-3) | First | -- |
| » Major-league debuts: Al Severinsen (Orioles) |
| Wednesday, July 2 |
| » Lost to Yankees (38-42), 3-2 | Yankee Stadium (4-2) | 55-23 | Lost 2 |
| » W: Mel Stottlemyre (11-6) L: Marcelino Lopez (3-2) | First | -- |
| Friday, July 4 |
| » Lost to Tigers (43-32), 4-1 | Tiger Stadium (1-2) | 55-24 | Lost 3 |
| » W: Mickey Lolich (11-1) L: Mike Cuellar (8-7) | First | -- |
| Former Oriole Lew Drill dies in St.Paul, MN at the age of 93. |
| Saturday, July 5 |
| » Defeated Tigers (43-33), 9-3 | Tiger Stadium (2-2) | 56-24 | |
| » W: Dave McNally (12-0) L: Pat Dobson (3-6) | First | -- |
| Sunday, July 6 |
| » Lost to Tigers (44-33), 5-4 | Tiger Stadium (2-3) | 56-25 | |
| » W: Denny McLain (13-5) L: Dave Leonhard (6-1) | First | -- |
| Tuesday, July 8 |
| » Defeated Yankees (40-45), 10-3 | Memorial Stadium (26-12) | 57-25 | |
| » W: Tom Phoebus (8-2) L: Fritz Peterson (9-10) | First | -- |
| » Defeated Yankees (40-46), 4-1 | Memorial Stadium (27-12) | 58-25 | Won 2 |
| » W: Mike Cuellar (9-7) L: Bill Burbach (5-7) | First | -- |
| Wednesday, July 9 |
| » Defeated Yankees (40-47), 6-5 | Memorial Stadium (28-12) | 59-25 | Won 3 |
| » W: Pete Richert (3-3) L: Ken Johnson (0-3) | First | -- |
| Thursday, July 10 |
| » Defeated Red Sox (47-39), 5-4 | Memorial Stadium (29-12) | 60-25 | Won 4 |
| » W: Jim Hardin (4-4) L: Vicente Romo (3-6) | First | -- |
| Friday, July 11 |
| » Lost to Red Sox (48-39), 7-4 | Memorial Stadium (29-13) | 60-26 | |
| » W: Ray Culp (12-6) L: Al Severinsen (0-1) S: Sparky Lyle (8) | First | -- |
| » Lost to Red Sox (49-39), 12-3 | Memorial Stadium (29-14) | 60-27 | Lost 2 |
| » W: Ray Jarvis (4-5) L: Dave Leonhard (6-2) S: Jim Lonborg (1) | First | -- |
| Saturday, July 12 |
| » Defeated Red Sox (49-40), 4-0 | Memorial Stadium (30-14) | 61-27 | |
| » W: Mike Cuellar (10-7) L: Mike Nagy (5-2) | First | -- |
| Sunday, July 13 |
| » Defeated Red Sox (49-41), 6-3 | Memorial Stadium (31-14) | 62-27 | Won 2 |
| » W: Dave McNally (13-0) L: Jim Lonborg (6-3) S: Eddie Watt (9) | First | -- |
| Tuesday, July 15 |
| » Defeated Indians (36-54), 5-1 | Memorial Stadium (32-14) | 63-27 | Won 3 |
| » W: Tom Phoebus (9-2) L: Sam McDowell (11-9) | First | -- |
| Wednesday, July 16 |
| » Lost to Indians (37-54), 6-4 | Memorial Stadium (32-15) | 63-28 | |
| » W: Dick Ellsworth (5-5) L: Mike Cuellar (10-8) S: Mike Paul (2) | First | -- |
| » Defeated Indians (37-55), 6-5 | Memorial Stadium (33-15) | 64-28 | |
| » W: Pete Richert (4-3) L: Stan Williams (3-8) | First | -- |
| Thursday, July 17 |
| » Defeated Indians (37-56), 3-2 | Memorial Stadium (34-15) | 65-28 | Won 2 |
| » W: Pete Richert (5-3) L: Stan Williams (3-9) | First | -- |
| Friday, July 18 |
| » Lost to Red Sox (52-42), 6-1 | Fenway Park (3-2) | 65-29 | |
| » W: Ray Jarvis (5-5) L: Dave Leonhard (6-3) | First | -- |
| Saturday, July 19 |
| » Lost to Red Sox (53-42), 5-3 | Fenway Park (3-3) | 65-30 | Lost 2 |
| » W: Sonny Siebert (8-8) L: Tom Phoebus (9-3) S: Sparky Lyle (9) | First | -- |
| Sunday, July 20 |
| » Lost to Red Sox (54-42), 6-5 | Fenway Park (3-4) | 65-31 | Lost 3 |
| » W: Ray Culp (14-6) L: Mike Cuellar (10-9) S: Sparky Lyle (10) | First | -- |
| Thursday, July 24 |
| » Defeated White Sox (40-57), 5-2 | Memorial Stadium (35-15) | 66-31 | |
| » W: Mike Cuellar (11-9) L: Tommy John (6-9) S: Eddie Watt (10) | First | -- |
| Friday, July 25 |
| » Defeated White Sox (40-58), 4-2 | Memorial Stadium (36-15) | 67-31 | Won 2 |
| » W: Dave McNally (14-0) L: Gary Peters (6-11) S: Dick Hall (3) | First | -- |
| Saturday, July 26 |
| » Defeated White Sox (40-59), 2-1 | Memorial Stadium (37-15) | 68-31 | Won 3 |
| » W: Tom Phoebus (10-3) L: Joe Horlen (6-12) S: Pete Richert (7) | First | -- |
| Sunday, July 27 |
| » Defeated White Sox (40-60), 17-0 | Memorial Stadium (38-15) | 69-31 | Won 4 |
| » W: Jim Hardin (5-4) L: Billy Wynne (3-2) | First | -- |
| Tuesday, July 29 |
| » Defeated Royals (42-59), 4-1 | Municipal Stadium (4-0) | 70-31 | Won 5 |
| » W: Mike Cuellar (12-9) L: Wally Bunker (5-8) | First | -- |
| Wednesday, July 30 |
| » Defeated Royals (42-60), 4-2 | Municipal Stadium (5-0) | 71-31 | Won 6 |
| » W: Dave McNally (15-0) L: Roger Nelson (6-10) S: Eddie Watt (11) | First | -- |
| Thursday, July 31 |
| » Defeated Royals (42-61), 3-1 | Municipal Stadium (6-0) | 72-31 | Won 7 |
| » W: Tom Phoebus (11-3) L: Jim Rooker (2-8) S: Dick Hall (4) | First | -- |
| Friday, August 1 |
| » Lost to Twins (65-40), 4-3 | Metropolitan Stadium (2-2) | 72-32 | |
| » W: Ron Perranoski (7-5) L: Dave Leonhard (6-4) | First | -- |
| Saturday, August 2 |
| » Defeated Twins (65-41), 6-5 | Metropolitan Stadium (3-2) | 73-32 | |
| » W: Mike Cuellar (13-9) L: Al Worthington (4-1) S: Pete Richert (8) | First | -- |
| Sunday, August 3 |
| » Lost to Twins (66-41), 5-2 | Metropolitan Stadium (3-3) | 73-33 | |
| » W: Jim Kaat (11-7) L: Dave McNally (15-1) S: Al Worthington (2) | First | -- |
| Monday, August 4 |
| » Lost to Indians (45-64), 2-0 | Cleveland Stadium (3-3) | 73-34 | Lost 2 |
| » W: Steve Hargan (4-8) L: Tom Phoebus (11-4) | First | -- |
| Tuesday, August 5 |
| » Defeated Royals (44-63), 7-5 | Memorial Stadium (39-15) | 74-34 | |
| » W: Eddie Watt (3-1) L: Galen Cisco (1-1) | First | -- |
| Wednesday, August 6 |
| » Defeated Royals (44-64), 2-1 | Memorial Stadium (40-15) | 75-34 | Won 2 |
| » W: Mike Cuellar (14-9) L: Jim Rooker (2-9) S: Pete Richert (9) | First | -- |
| Thursday, August 7 |
| » Defeated Royals (44-65), 10-2 | Memorial Stadium (41-15) | 76-34 | Won 3 |
| » W: Dave McNally (16-1) L: Dick Drago (5-10) | First | -- |
| Friday, August 8 |
| » Defeated Twins (68-44), 6-5 | Memorial Stadium (42-15) | 77-34 | Won 4 |
| » W: Marcelino Lopez (4-2) L: Ron Perranoski (7-6) | First | -- |
| Saturday, August 9 |
| » Defeated Twins (68-45), 5-1 | Memorial Stadium (43-15) | 78-34 | Won 5 |
| » W: Jim Palmer (10-2) L: Dean Chance (3-2) S: Pete Richert (10) | First | -- |
| Sunday, August 10 |
| » Defeated Twins (68-46), 2-0 | Memorial Stadium (44-15) | 79-34 | Won 6 |
| » W: Mike Cuellar (15-9) L: Jim Perry (13-5) | First | -- |
| Monday, August 11 |
| » Lost to Athletics (66-46), 7-4 | Memorial Stadium (44-16) | 79-35 | |
| » W: Jim Nash (5-7) L: Dave McNally (16-2) S: Rollie Fingers (12) | First | -- |
| Tuesday, August 12 |
| » Defeated Athletics (66-47), 4-3 | Memorial Stadium (45-16) | 80-35 | |
| » W: Pete Richert (6-3) L: Paul Lindblad (7-3) | First | -- |
| Wednesday, August 13 |
| » Defeated Athletics (66-48), 8-0 | Memorial Stadium (46-16) | 81-35 | Won 2 |
| » W: Jim Palmer (11-2) L: Chuck Dobson (13-9) | First | -- |
| Friday, August 15 |
| » Defeated Pilots (48-67), 2-1 | Sick's Stadium (2-1) | 82-35 | Won 3 |
| » W: Mike Cuellar (16-9) L: Gene Brabender (9-9) | First | -- |
| » Major-league debuts: Billy Williams (Pilots) |
| Saturday, August 16 |
| » Defeated Pilots (48-68), 15-3 | Sick's Stadium (3-1) | 83-35 | Won 4 |
| » W: Dave McNally (17-2) L: Diego Segui (9-5) S: Jim Hardin (1) | First | -- |
| Sunday, August 17 |
| » Defeated Pilots (48-69), 4-1 | Sick's Stadium (4-1) | 84-35 | Won 5 |
| » W: Tom Phoebus (12-4) L: Fred Talbot (5-6) S: Eddie Watt (12) | First | -- |
| Monday, August 18 |
| » Defeated Pilots (48-70), 12-3 | Sick's Stadium (5-1) | 85-35 | Won 6 |
| » W: Jim Palmer (12-2) L: George Brunet (7-10) | First | -- |
| Tuesday, August 19 |
| » Defeated Angels (47-70), 10-0 | Anaheim Stadium (3-1) | 86-35 | Won 7 |
| » W: Mike Cuellar (17-9) L: Rudy May (5-10) | First | -- |
| Wednesday, August 20 |
| » Lost to Angels (48-70), 3-2 | Anaheim Stadium (3-2) | 86-36 | |
| » W: Andy Messersmith (12-8) L: Dave McNally (17-3) S: Ken Tatum (10) | First | -- |
| Thursday, August 21 |
| » Lost to Angels (49-70), 2-0 | Anaheim Stadium (3-3) | 86-37 | Lost 2 |
| » W: Steve Kealey (1-0) L: Tom Phoebus (12-5) | First | -- |
| Friday, August 22 |
| » Defeated Athletics (69-51), 4-3 | Oakland-Alameda County Stadium (3-0) | 87-37 | |
| » W: Jim Palmer (13-2) L: Paul Lindblad (7-4) S: Eddie Watt (13) | First | -- |
| Saturday, August 23 |
| » Lost to Athletics (70-51), 4-2 | Oakland-Alameda County Stadium (3-1) | 87-38 | |
| » W: Paul Lindblad (8-4) L: Mike Cuellar (17-10) S: Vida Blue (1) | First | -- |
| Sunday, August 24 |
| » Lost to Athletics (71-51), 9-0 | Oakland-Alameda County Stadium (3-2) | 87-39 | Lost 2 |
| » W: Chuck Dobson (14-10) L: Dave McNally (17-4) | First | -- |
| » Lost to Athletics (72-51), 9-8 | Oakland-Alameda County Stadium (3-3) | 87-40 | Lost 3 |
| » W: Jim Nash (6-7) L: Marcelino Lopez (4-3) | First | -- |
| Tuesday, August 26 |
| » Lost to Pilots (49-76), 2-1 | Memorial Stadium (46-17) | 87-41 | Lost 4 |
| » W: Gene Brabender (10-10) L: Tom Phoebus (12-6) | First | -- |
| Wednesday, August 27 |
| » Defeated Pilots (49-77), 7-2 | Memorial Stadium (47-17) | 88-41 | |
| » W: Mike Cuellar (18-10) L: George Brunet (7-11) | First | -- |
| Thursday, August 28 |
| » Defeated Pilots (49-78), 4-3 | Memorial Stadium (48-17) | 89-41 | Won 2 |
| » W: Eddie Watt (4-1) L: Dooley Womack (2-2) | First | -- |
| Friday, August 29 |
| » Lost to Angels (54-71), 6-2 | Memorial Stadium (48-18) | 89-42 | |
| » W: Andy Messersmith (13-8) L: Dave McNally (17-5) S: Ken Tatum (14) | First | -- |
| » Lost to Angels (55-71), 2-1 | Memorial Stadium (48-19) | 89-43 | Lost 2 |
| » W: Jim McGlothlin (7-12) L: Jim Hardin (5-5) | First | -- |
| Saturday, August 30 |
| » Defeated Angels (55-72), 6-3 | Memorial Stadium (49-19) | 90-43 | |
| » W: Dave Leonhard (7-4) L: Clyde Wright (1-7) | First | -- |
| Sunday, August 31 |
| » Defeated Angels (55-73), 5-4 | Memorial Stadium (50-19) | 91-43 | Won 2 |
| » W: Mike Cuellar (19-10) L: Rudy May (6-11) S: Dick Hall (5) | First | -- |
| Monday, September 1 |
| » Defeated White Sox (52-79), 8-0 | County Stadium (1-0) | 92-43 | Won 3 |
| » W: Jim Palmer (14-2) L: Billy Wynne (4-5) | First | -- |
| Tuesday, September 2 |
| » Lost to White Sox (53-79), 10-3 | Comiskey Park I (4-1) | 92-44 | |
| » W: Gary Peters (9-13) L: Dave McNally (17-6) S: Wilbur Wood (11) | First | -- |
| Wednesday, September 3 |
| » Major-league debuts: Oscar Brown (Braves) |
| Thursday, September 4 |
| » Defeated Tigers (79-57), 5-4 | Tiger Stadium (3-3) | 93-44 | |
| » W: Pete Richert (7-3) L: Tom Timmermann (2-2) | First | -- |
| » Major-league debuts: Terry Crowley (Orioles) |
| Friday, September 5 |
| » Defeated Tigers (79-58), 8-4 | Tiger Stadium (4-3) | 94-44 | Won 2 |
| » W: Mike Cuellar (20-10) L: Mike Kilkenny (4-5) | First | -- |
| Saturday, September 6 |
| » Lost to Tigers (80-58), 5-4 | Tiger Stadium (4-4) | 94-45 | |
| » W: Tom Timmermann (3-2) L: Eddie Watt (4-2) | First | -- |
| Sunday, September 7 |
| » Defeated Tigers (80-59), 6-5 | Tiger Stadium (5-4) | 95-45 | |
| » W: Eddie Watt (5-2) L: Pat Dobson (4-10) | First | -- |
| Tuesday, September 9 |
| » Defeated Senators (72-69), 6-1 | Memorial Stadium (51-19) | 96-45 | Won 2 |
| » W: Mike Cuellar (21-10) L: Cisco Carlos (5-4) | First | -- |
| » Defeated Senators (72-70), 3-2 | Memorial Stadium (52-19) | 97-45 | Won 3 |
| » W: Tom Phoebus (13-6) L: Joe Coleman (10-13) S: Eddie Watt (14) | First | -- |
| Wednesday, September 10 |
| » Defeated Red Sox (76-64), 8-7 | Memorial Stadium (53-19) | 98-45 | Won 4 |
| » W: Al Severinsen (1-1) L: Gary Wagner (0-4) S: Eddie Watt (15) | First | -- |
| Thursday, September 11 |
| » Defeated Red Sox (76-65), 4-2 | Memorial Stadium (54-19) | 99-45 | Won 5 |
| » W: Dave McNally (18-6) L: Lee Stange (6-8) | First | -- |
| Friday, September 12 |
| » Defeated Indians (57-88), 2-1 | Memorial Stadium (55-19) | 100-45 | Won 6 |
| » W: Jim Hardin (6-5) L: Stan Williams (5-12) S: Pete Richert (11) | First | -- |
| Saturday, September 13 |
| » Defeated Indians (57-89), 10-5 | Memorial Stadium (56-19) | 101-45 | Won 7 |
| » W: Tom Phoebus (14-6) L: Steve Hargan (5-13) S: Dave Leonhard (1) | First | -- |
| Sunday, September 14 |
| » Defeated Indians (57-90), 7-3 | Memorial Stadium (57-19) | 102-45 | Won 8 |
| » W: Mike Cuellar (22-10) L: Sam McDowell (16-14) | First | -- |
| Monday, September 15 |
| » Lost to Senators (77-71), 3-2 | Robert F. Kennedy Stadium (5-3) | 102-46 | |
| » W: Bob Humphreys (3-3) L: Jim Palmer (14-3) | First | -- |
| Tuesday, September 16 |
| » Defeated Senators (77-72), 1-0 | Robert F. Kennedy Stadium (6-3) | 103-46 | |
| » W: Dave McNally (19-6) L: Jim Hannan (6-6) S: Eddie Watt (16) | First | -- |
| Thursday, September 18 |
| » Defeated Red Sox (78-70), 6-4 | Fenway Park (4-4) | 104-46 | Won 2 |
| » W: Mike Cuellar (23-10) L: Gary Wagner (1-5) S: Dick Hall (6) | First | -- |
| » Lost to Red Sox (79-70), 5-0 | Fenway Park (4-5) | 104-47 | |
| » W: Vicente Romo (7-10) L: Jim Hardin (6-6) | First | -- |
| » Major-league debuts: Carlton Fisk (Red Sox) |
| Friday, September 19 |
| » Defeated Yankees (75-76), 4-2 | Memorial Stadium (58-19) | 105-47 | |
| » W: Jim Palmer (15-3) L: Mike Kekich (2-6) | First | -- |
| Saturday, September 20 |
| » Defeated Yankees (75-77), 8-7 | Memorial Stadium (59-19) | 106-47 | Won 2 |
| » W: Marcelino Lopez (5-3) L: Jack Aker (8-6) S: Pete Richert (12) | First | -- |
| Monday, September 22 |
| Future Oriole Cesar Devarez is born in San Francisco De Macoris, D.R. |
| Tuesday, September 23 |
| » Lost to Indians (62-92), 3-1 | |
