| Sunday, January 8 |
| Future Tiger Randy Nosek is born in Omaha, NE. |
| Friday, January 13 |
| Former Tiger Charley Gelbert dies in Easton, PA at the age of 61. |
| Thursday, January 26 |
| Future Tiger Tim Pugh is born in South Lake Tahoe, CA. |
| Monday, February 20 |
| Future Tiger Kurt Knudsen is born in Arlington Heights, IL. |
| Sunday, March 26 |
| Future Tiger Shawn Hare is born in St. Louis, MO. |
| Tuesday, April 11 |
| » Lost to Angels (1-0), 4-2 | Anaheim Stadium (0-1) | 0-1 | |
| » W: George Brunet (1-0) L: Denny McLain (0-1) | Third | 1 out |
| » Major-league debuts: Jim Price (Tigers) |
| Wednesday, April 12 |
| » Defeated Angels (1-1), 6-3 | Anaheim Stadium (1-1) | 1-1 | |
| » W: Mickey Lolich (1-0) L: Marcelino Lopez (0-1) | Second | ½ out |
| Friday, April 14 |
| » Lost to Twins (1-2), 5-3 | Metropolitan Stadium (0-1) | 1-2 | |
| » W: Jim Merritt (1-0) L: Earl Wilson (0-1) | Fourth | 2 out |
| Saturday, April 15 |
| » Defeated Twins (1-3), 4-3 | Metropolitan Stadium (1-1) | 2-2 | |
| » W: Dave Wickersham (1-0) L: Jim Kaat (0-2) S: Fred Gladding (1) | Third | 1 out |
| Sunday, April 16 |
| » Defeated Athletics (2-2), 6-3 | Municipal Stadium (1-0) | 3-2 | Won 2 |
| » W: Denny McLain (1-1) L: Blue Moon Odom (0-1) | Fourth | 1 out |
| » Lost to Athletics (3-2), 11-7 | Municipal Stadium (1-1) | 3-3 | |
| » W: Jack Aker (1-0) L: Orlando Pena (0-1) S: Paul Lindblad (1) | Fourth | 1 out |
| Tuesday, April 18 |
| » Defeated Angels (3-4), 4-1 | Tiger Stadium (1-0) | 4-3 | |
| » W: Earl Wilson (1-1) L: Marcelino Lopez (0-2) | Third | ½ out |
| Thursday, April 20 |
| » Defeated Angels (3-5), 4-3 | Tiger Stadium (2-0) | 5-3 | Won 2 |
| » W: Fred Gladding (1-0) L: George Brunet (1-1) | Second | 1 out |
| Friday, April 21 |
| » Defeated Twins (2-5), 12-4 | Tiger Stadium (3-0) | 6-3 | Won 3 |
| » W: Denny McLain (2-1) L: Dave Boswell (0-1) | First | -- |
| Saturday, April 22 |
| » Lost to Twins (3-5), 4-3 | Tiger Stadium (3-1) | 6-4 | |
| » W: Jim Kaat (1-2) L: Mickey Lolich (1-1) S: Al Worthington (1) | First | -- |
| Sunday, April 23 |
| » Lost to Twins (4-5), 4-2 | Tiger Stadium (3-2) | 6-5 | Lost 2 |
| » W: Al Worthington (1-0) L: Earl Wilson (1-2) | Third | ½ out |
| Tuesday, April 25 |
| » Defeated Athletics (5-7), 5-0 | Tiger Stadium (4-2) | 7-5 | |
| » W: Joe Sparma (1-0) L: Lew Krausse (0-3) | Second | 1 out |
| Friday, April 28 |
| » Lost to Orioles (8-5), 5-3 | Memorial Stadium (0-1) | 7-6 | |
| » W: Dave McNally (1-0) L: Denny McLain (2-2) S: Moe Drabowsky (1) | Fourth | 1 out |
| Saturday, April 29 |
| » Defeated Orioles (8-6), 4-2 | Memorial Stadium (1-1) | 8-6 | |
| » W: Mickey Lolich (2-1) L: Wally Bunker (1-2) | Second | ½ out |
| Sunday, April 30 |
| » Defeated Orioles (8-7), 2-1 | Memorial Stadium (2-1) | 9-6 | Won 2 |
| » W: Earl Wilson (2-2) L: Steve Barber (2-1) S: Fred Gladding (2) | First | -- |
| » Defeated Orioles (8-8), 6-4 | Memorial Stadium (3-1) | 10-6 | Won 3 |
| » W: Joe Sparma (2-0) L: Jim Palmer (1-1) S: Dave Wickersham (1) | First | -- |
| Wednesday, May 3 |
| » Lost to White Sox (10-7), 2-1 | Comiskey Park I (0-1) | 10-7 | |
| » W: Gary Peters (2-1) L: Denny McLain (2-3) S: Bob Locker (2) | First | -- |
| Friday, May 5 |
| » Defeated Orioles (9-10), 4-0 | Tiger Stadium (5-2) | 11-7 | |
| » W: Mickey Lolich (3-1) L: Steve Barber (2-2) | First | -- |
| Saturday, May 6 |
| » Defeated Orioles (9-11), 4-1 | Tiger Stadium (6-2) | 12-7 | Won 2 |
| » W: Earl Wilson (3-2) L: Stu Miller (0-3) | First | -- |
| Sunday, May 7 |
| » Defeated Orioles (9-12), 4-0 | Tiger Stadium (7-2) | 13-7 | Won 3 |
| » W: Joe Sparma (3-0) L: Dave McNally (1-2) | First | -- |
| Tuesday, May 9 |
| » Defeated Indians (8-12), 4-3 | Cleveland Stadium (1-0) | 14-7 | Won 4 |
| » W: Denny McLain (3-3) L: Sam McDowell (2-1) S: Fred Gladding (3) | First | -- |
| Wednesday, May 10 |
| » Defeated Indians (8-13), 4-2 | Cleveland Stadium (2-0) | 15-7 | Won 5 |
| » W: Mickey Lolich (4-1) L: Sonny Siebert (2-2) S: Fred Gladding (4) | First | -- |
| Friday, May 12 |
| » Defeated Red Sox (11-13), 5-4 | Fenway Park (1-0) | 16-7 | Won 6 |
| » W: Earl Wilson (4-2) L: Bucky Brandon (0-4) S: Fred Gladding (5) | First | -- |
| Saturday, May 13 |
| » Defeated Red Sox (11-14), 10-8 | Fenway Park (2-0) | 17-7 | Won 7 |
| » W: George Korince (1-0) L: John Wyatt (2-1) | First | -- |
| Sunday, May 14 |
| » Lost to Red Sox (12-14), 8-5 | Fenway Park (2-1) | 17-8 | |
| » W: Jim Lonborg (3-1) L: Denny McLain (3-4) S: Hank Fischer (1) | Second | 1½ out |
| » Lost to Red Sox (13-14), 13-9 | Fenway Park (2-2) | 17-9 | Lost 2 |
| » W: Jose Santiago (2-1) L: Mickey Lolich (4-2) | Second | 1½ out |
| Tuesday, May 16 |
| » Lost to Senators (13-15), 5-4 | Robert F. Kennedy Stadium (0-1) | 17-10 | Lost 3 |
| » W: Camilo Pascual (3-1) L: Earl Wilson (4-3) S: Dave Baldwin (2) | Second | 1½ out |
| Future Tiger Doug Brocail is born in Clearfield, PA. |
| Wednesday, May 17 |
| » Defeated Senators (13-16), 8-1 | Robert F. Kennedy Stadium (1-1) | 18-10 | |
| » W: Joe Sparma (4-0) L: Barry Moore (2-1) | Second | 1½ out |
| Friday, May 19 |
| » Defeated Yankees (13-15), 4-2 | Tiger Stadium (8-2) | 19-10 | Won 2 |
| » W: Mickey Lolich (5-2) L: Mel Stottlemyre (3-3) | Second | 1½ out |
| Saturday, May 20 |
| » Defeated Yankees (13-16), 3-1 | Tiger Stadium (9-2) | 20-10 | Won 3 |
| » W: Denny McLain (4-4) L: Al Downing (3-3) | Second | ½ out |
| Sunday, May 21 |
| » Defeated Yankees (13-17), 9-4 | Tiger Stadium (10-2) | 21-10 | Won 4 |
| » W: Earl Wilson (5-3) L: Whitey Ford (2-4) S: Fred Gladding (6) | Second | 1 out |
| » Lost to Yankees (14-17), 6-5 | Tiger Stadium (10-3) | 21-11 | |
| » W: Steve Hamilton (1-0) L: Larry Sherry (0-1) | Second | 1 out |
| Tuesday, May 23 |
| » Lost to Red Sox (17-17), 5-2 | Tiger Stadium (10-4) | 21-12 | Lost 2 |
| » W: Dennis Bennett (2-1) L: Mickey Lolich (5-3) S: John Wyatt (2) | Second | ½ out |
| Wednesday, May 24 |
| » Lost to Red Sox (18-17), 1-0 | Tiger Stadium (10-5) | 21-13 | Lost 3 |
| » W: Jim Lonborg (5-1) L: Denny McLain (4-5) | Second | 1½ out |
| Thursday, May 25 |
| » Defeated Red Sox (18-18), 9-3 | Tiger Stadium (11-5) | 22-13 | |
| » W: Earl Wilson (6-3) L: Jose Santiago (2-2) | Second | 1 out |
| Friday, May 26 |
| » Defeated Senators (15-22), 10-5 | Tiger Stadium (12-5) | 23-13 | Won 2 |
| » W: Dave Wickersham (2-0) L: Darold Knowles (3-2) | Second | ½ out |
| Saturday, May 27 |
| » Lost to Senators (16-22), 8-1 | Tiger Stadium (12-6) | 23-14 | |
| » W: Camilo Pascual (4-2) L: Mickey Lolich (5-4) | Second | 1½ out |
| Sunday, May 28 |
| » Defeated Senators (16-23), 3-1 | Tiger Stadium (13-6) | 24-14 | |
| » W: Denny McLain (5-5) L: Pete Richert (2-6) S: Fred Gladding (7) | Second | ½ out |
| Tuesday, May 30 |
| » Defeated White Sox (24-14), 4-2 | Tiger Stadium (14-6) | 25-14 | Won 2 |
| » W: Earl Wilson (7-3) L: Gary Peters (6-2) S: Fred Gladding (8) | First | -- |
| » Defeated White Sox (24-15), 4-3 | Tiger Stadium (15-6) | 26-14 | Won 3 |
| » W: Dave Wickersham (3-0) L: Bruce Howard (1-3) S: Fred Gladding (9) | First | -- |
| Wednesday, May 31 |
| » Lost to Indians (21-20), 9-0 | Tiger Stadium (15-7) | 26-15 | |
| » W: Luis Tiant (3-1) L: Mickey Lolich (5-5) | First | -- |
| » Major-league debuts: Pat Dobson and Mike Marshall (Tigers) |
| Thursday, June 1 |
| » Lost to Indians (22-20), 8-2 | Tiger Stadium (15-8) | 26-16 | Lost 2 |
| » W: John O'Donoghue (1-0) L: Denny McLain (5-6) | Second | 1 out |
| Friday, June 2 |
| » Defeated Yankees (18-23), 9-5 | Yankee Stadium (1-0) | 27-16 | |
| » W: Joe Sparma (5-0) L: Mel Stottlemyre (4-5) | First | -- |
| Saturday, June 3 |
| » Lost to Yankees (19-23), 3-1 | Yankee Stadium (1-1) | 27-17 | |
| » W: Joe Verbanic (1-0) L: Earl Wilson (7-4) S: Dooley Womack (4) | First | -- |
| Sunday, June 4 |
| » Lost to Yankees (20-23), 5-0 | Yankee Stadium (1-2) | 27-18 | Lost 2 |
| » W: Al Downing (6-3) L: Mickey Lolich (5-6) | First | -- |
| » Defeated Yankees (20-24), 11-7 | Yankee Stadium (2-2) | 28-18 | |
| » W: Johnny Podres (1-0) L: Dooley Womack (3-3) | First | -- |
| Monday, June 5 |
| » Defeated Athletics (22-26), 3-2 | Municipal Stadium (2-1) | 29-18 | Won 2 |
| » W: Denny McLain (6-6) L: Jack Aker (2-4) | First | -- |
| Tuesday, June 6 |
| » Defeated Athletics (22-27), 11-1 | Municipal Stadium (3-1) | 30-18 | Won 3 |
| » W: Earl Wilson (8-4) L: Lew Krausse (3-8) | First | -- |
| » Defeated Athletics (22-28), 7-1 | Municipal Stadium (4-1) | 31-18 | Won 4 |
| » W: Joe Sparma (6-0) L: Blue Moon Odom (2-3) | First | -- |
| Wednesday, June 7 |
| » Lost to Athletics (23-28), 4-2 | Municipal Stadium (4-2) | 31-19 | |
| » W: Paul Lindblad (4-0) L: Mickey Lolich (5-7) S: Tony Pierce (4) | First | -- |
| Friday, June 9 |
| » Lost to Angels (23-32), 4-0 | Anaheim Stadium (1-2) | 31-20 | Lost 2 |
| » W: George Brunet (2-9) L: Denny McLain (6-7) | First | -- |
| Saturday, June 10 |
| » Lost to Angels (24-32), 2-0 | Anaheim Stadium (1-3) | 31-21 | Lost 3 |
| » W: Clyde Wright (1-0) L: Earl Wilson (8-5) S: Minnie Rojas (4) | First | -- |
| Sunday, June 11 |
| » Lost to Angels (25-32), 6-4 | Anaheim Stadium (1-4) | 31-22 | Lost 4 |
| » W: Minnie Rojas (4-4) L: Fred Gladding (1-1) | Second | 1 out |
| Future Tiger John Doherty is born in New York, NY. |
| Monday, June 12 |
| » Lost to Twins (28-27), 11-5 | Metropolitan Stadium (1-2) | 31-23 | Lost 5 |
| » W: Jim Merritt (4-0) L: Mickey Lolich (5-8) | Second | 1 out |
| Tuesday, June 13 |
| » Defeated Twins (28-28), 15-10 | Metropolitan Stadium (2-2) | 32-23 | |
| » W: Denny McLain (7-7) L: Dean Chance (9-4) S: Dave Wickersham (2) | Second | 1 out |
| Wednesday, June 14 |
| » Lost to Twins (29-28), 7-0 | Metropolitan Stadium (2-3) | 32-24 | |
| » W: Jim Kaat (3-7) L: Earl Wilson (8-6) | Second | 1½ out |
| Thursday, June 15 |
| » Lost to Twins (30-28), 6-4 | Metropolitan Stadium (2-4) | 32-25 | Lost 2 |
| » W: Ron Kline (3-0) L: Fred Gladding (1-2) | Second | 1½ out |
| Saturday, June 17 |
| » Defeated Athletics (29-32), 7-6 | Tiger Stadium (16-8) | 33-25 | |
| » W: Fred Gladding (2-2) L: Diego Segui (1-3) | Second | 2 out |
| » Lost to Athletics (30-32), 6-5 | Tiger Stadium (16-9) | 33-26 | |
| » W: Bill Edgerton (1-0) L: Mike Marshall (0-1) | Second | 2 out |
| Sunday, June 18 |
| » Lost to Athletics (31-32), 8-4 | Tiger Stadium (16-10) | 33-27 | Lost 2 |
| » W: Catfish Hunter (7-4) L: Joe Sparma (6-1) S: Tony Pierce (5) | Second | 3½ out |
| Monday, June 19 |
| » Lost to Angels (32-34), 2-0 | Tiger Stadium (16-11) | 33-28 | Lost 3 |
| » W: Clyde Wright (2-0) L: Mickey Lolich (5-9) S: Minnie Rojas (6) | Second | 3½ out |
| » Defeated Angels (32-35), 5-1 | Tiger Stadium (17-11) | 34-28 | |
| » W: Denny McLain (8-7) L: Ken Turner (1-1) | Second | 3½ out |
| Tuesday, June 20 |
| » Defeated Angels (32-36), 2-1 | Tiger Stadium (18-11) | 35-28 | Won 2 |
| » W: Dave Wickersham (4-0) L: George Brunet (3-11) | Second | 2½ out |
| Wednesday, June 21 |
| » Tied Twins, 5-5 | Tiger Stadium (18-11) | 35-28 | |
| » Starters: Jim Merritt vs Earl Wilson | Second | 3½ out |
| Thursday, June 22 |
| » Defeated Twins (32-32), 5-2 | Tiger Stadium (19-11) | 36-28 | Won 3 |
| » W: Joe Sparma (7-1) L: Jim Kaat (4-8) | Second | 3 out |
| Friday, June 23 |
| » Lost to Yankees (29-35), 3-1 | Yankee Stadium (2-3) | 36-29 | |
| » W: Al Downing (8-4) L: Denny McLain (8-8) | Second | 3 out |
| Saturday, June 24 |
| » Lost to Yankees (30-35), 4-3 | Yankee Stadium (2-4) | 36-30 | Lost 2 |
| » W: Dooley Womack (4-3) L: Fred Gladding (2-3) | Second | 4 out |
| Sunday, June 25 |
| » Lost to Yankees (31-35), 3-2 | Yankee Stadium (2-5) | 36-31 | Lost 3 |
| » W: Mel Stottlemyre (7-7) L: Mickey Lolich (5-10) S: Dooley Womack (6) | Second | 4 out |
| Tuesday, June 27 |
| » Lost to Indians (35-34), 8-1 | Tiger Stadium (19-12) | 36-32 | Lost 4 |
| » W: Sam McDowell (4-6) L: Earl Wilson (8-7) | Second | 5½ out |
| Wednesday, June 28 |
| » Defeated Indians (35-35), 7-4 | Tiger Stadium (20-12) | 37-32 | |
| » W: Joe Sparma (8-1) L: Orlando Pena (0-2) S: Dave Wickersham (3) | Second | 5½ out |
| Thursday, June 29 |
| » Lost to Indians (36-35), 5-3 | Tiger Stadium (20-13) | 37-33 | |
| » W: Luis Tiant (7-2) L: Denny McLain (8-9) S: George Culver (2) | Second | 5½ out |
| Friday, June 30 |
| » Defeated White Sox (42-28), 4-1 | Tiger Stadium (21-13) | 38-33 | |
| » W: Johnny Podres (2-0) L: Tommy John (6-5) S: Mike Marshall (1) | Second | 4½ out |
| Saturday, July 1 |
| » Lost to White Sox (43-28), 6-5 | Tiger Stadium (21-14) | 38-34 | |
| » W: Joe Horlen (10-1) L: Dave Wickersham (4-1) S: Hoyt Wilhelm (7) | Second | 5½ out |
| Sunday, July 2 |
| » Defeated White Sox (43-29), 3-0 | Tiger Stadium (22-14) | 39-34 | |
| » W: Joe Sparma (9-1) L: Gary Peters (10-4) | Second | 4½ out |
| Monday, July 3 |
| » Defeated Indians (38-38), 2-1 | Cleveland Stadium (3-0) | 40-34 | Won 2 |
| » W: Denny McLain (9-9) L: Luis Tiant (7-3) | Second | 3½ out |
| Tuesday, July 4 |
| » Defeated Indians (38-39), 6-1 | Cleveland Stadium (4-0) | 41-34 | Won 3 |
| » W: Earl Wilson (9-7) L: Steve Hargan (9-7) | Third | 3½ out |
| Wednesday, July 5 |
| » Defeated Indians (38-40), 3-2 | Cleveland Stadium (5-0) | 42-34 | Won 4 |
| » W: Fred Gladding (3-3) L: George Culver (5-1) S: Mike Marshall (2) | Third | 3½ out |
| Future Tiger Tim Worrell is born in Pasadena, CA. |
| Thursday, July 6 |
| Future Tiger Omar Olivares is born in Mayaguez, P.R. |
| Friday, July 7 |
| » Defeated Red Sox (40-37), 5-4 | Tiger Stadium (23-14) | 43-34 | Won 5 |
| » W: Mike Marshall (1-1) L: John Wyatt (4-4) | Second | 3 out |
| Saturday, July 8 |
| » Defeated Red Sox (40-38), 2-0 | Tiger Stadium (24-14) | 44-34 | Won 6 |
| » W: Denny McLain (10-9) L: Lee Stange (3-6) | Second | 3 out |
| Sunday, July 9 |
| » Defeated Red Sox (40-39), 10-4 | Tiger Stadium (25-14) | 45-34 | Won 7 |
| » W: Earl Wilson (10-7) L: Gary Bell (6-8) | Second | 2 out |
| » Lost to Red Sox (41-39), 3-0 | Tiger Stadium (25-15) | 45-35 | |
| » W: Jim Lonborg (11-3) L: Dave Wickersham (4-2) S: John Wyatt (11) | Second | 2 out |
| Thursday, July 13 |
| » Lost to Senators (37-47), 8-3 | Robert F. Kennedy Stadium (1-2) | 45-36 | Lost 2 |
| » W: Camilo Pascual (8-6) L: Joe Sparma (9-2) | Third | 3 out |
| » Lost to Senators (38-47), 6-1 | Robert F. Kennedy Stadium (1-3) | 45-37 | Lost 3 |
| » W: Joe Coleman (5-6) L: Denny McLain (10-10) | Third | 3 out |
| Friday, July 14 |
| » Lost to Senators (39-47), 3-1 | Robert F. Kennedy Stadium (1-4) | 45-38 | Lost 4 |
| » W: Phil Ortega (7-5) L: Earl Wilson (10-8) S: Dave Baldwin (7) | Third | 3½ out |
| Saturday, July 15 |
| » Lost to Senators (40-47), 3-2 | Robert F. Kennedy Stadium (1-5) | 45-39 | Lost 5 |
| » W: Casey Cox (3-1) L: Mickey Lolich (5-11) S: Dick Lines (1) | Third | 3½ out |
| Sunday, July 16 |
| » Lost to Red Sox (45-40), 9-5 | Fenway Park (2-3) | 45-40 | Lost 6 |
| » W: Bucky Brandon (3-7) L: Joe Sparma (9-3) S: Sparky Lyle (1) | Third | 4 out |
| Monday, July 17 |
| » Lost to Red Sox (46-40), 7-1 | Fenway Park (2-4) | 45-41 | Lost 7 |
| » W: Lee Stange (5-6) L: Denny McLain (10-11) | Fourth | 4½ out |
| Tuesday, July 18 |
| » Defeated Senators (42-48), 5-2 | Tiger Stadium (26-15) | 46-41 | |
| » W: Earl Wilson (11-8) L: Camilo Pascual (8-7) | Fourth | 3½ out |
| Wednesday, July 19 |
| » Lost to Senators (43-48), 4-2 | Tiger Stadium (26-16) | 46-42 | |
| » W: Darold Knowles (5-5) L: Fred Gladding (3-4) | Fifth | 3½ out |
| Thursday, July 20 |
| » Defeated Senators (43-49), 8-4 | Tiger Stadium (27-16) | 47-42 | |
| » W: Joe Sparma (10-3) L: Barry Moore (5-8) | Fifth | 3 out |
| Friday, July 21 |
| » Defeated Yankees (39-51), 4-2 | Tiger Stadium (28-16) | 48-42 | Won 2 |
| » W: Denny McLain (11-11) L: Steve Barber (5-11) S: Mike Marshall (3) | Fifth | 3 out |
| Saturday, July 22 |
| » Defeated Yankees (39-52), 11-4 | Tiger Stadium (29-16) | 49-42 | Won 3 |
| » W: Earl Wilson (12-8) L: Fred Talbot (5-4) S: Mike Marshall (4) | Fourth | 2 out |
| Sunday, July 23 |
| » Lost to Yankees (40-52), 4-2 | Tiger Stadium (29-17) | 49-43 | |
| » W: Mel Stottlemyre (8-10) L: Mickey Lolich (5-12) S: Steve Hamilton (2) | Fourth | 3 out |
| » Defeated Yankees (40-53), 7-3 | Tiger Stadium (30-17) | 50-43 | |
| » W: John Hiller (1-0) L: Fritz Peterson (2-10) S: Mike Marshall (5) | Fourth | 3 out |
| Thursday, July 27 |
| » Defeated Orioles (43-52), 4-0 | Memorial Stadium (4-1) | 51-43 | Won 2 |
| » W: Denny McLain (12-11) L: Tom Phoebus (8-6) | Third | 3½ out |
| Friday, July 28 |
| » Defeated White Sox (55-41), 7-4 | Comiskey Park I (1-1) | 52-43 | Won 3 |
| » W: Earl Wilson (13-8) L: Gary Peters (12-6) S: Mike Marshall (6) | Third | 2½ out |
| Saturday, July 29 |
| » Lost to White Sox (56-41), 4-3 | Comiskey Park I (1-2) | 52-44 | |
| » W: Wilbur Wood (3-0) L: Joe Sparma (10-4) S: Don McMahon (3) | Third | 3½ out |
| Sunday, July 30 |
| » Lost to White Sox (57-41), 4-1 | Comiskey Park I (1-3) | 52-45 | Lost 2 |
| » W: Joe Horlen (13-3) L: Denny McLain (12-12) | Third | 3½ out |
| » Defeated White Sox (57-42), 7-1 | Comiskey Park I (2-3) | 53-45 | |
| » W: Johnny Podres (3-0) L: Bruce Howard (3-8) | Third | 3½ out |
| Tuesday, August 1 |
| » Defeated Orioles (45-55), 4-2 | Memorial Stadium (5-1) | 54-45 | Won 2 |
| » W: Earl Wilson (14-8) L: Tom Phoebus (8-7) S: John Hiller (1) | Third | 4 out |
| Future Tiger Gregg Jefferies is born in Burlingame, CA. |
| Wednesday, August 2 |
| » Defeated Orioles (45-56), 4-2 | Memorial Stadium (6-1) | 55-45 | Won 3 |
| » W: Joe Sparma (11-4) L: Gene Brabender (0-2) S: John Hiller (2) | Third | 3½ out |
| » Lost to Orioles (46-56), 2-1 | Memorial Stadium (6-2) | 55-46 | |
| » W: Moe Drabowsky (7-1) L: Pat Dobson (0-1) | Third | 3½ out |
| Thursday, August 3 |
| » Defeated Orioles (46-57), 5-0 | Memorial Stadium (7-2) | 56-46 | |
| » W: Denny McLain (13-12) L: Bill Dillman (5-5) | Third | 3 out |
| Friday, August 4 |
| » Lost to Indians (48-57), 11-5 | Cleveland Stadium (5-1) | 56-47 | |
| » W: Sam McDowell (9-9) L: Johnny Podres (3-1) S: Sonny Siebert (1) | Third | 3½ out |
| Saturday, August 5 |
| » Lost to Indians (49-57), 5-3 | Cleveland Stadium (5-2) | 56-48 | Lost 2 |
| » W: Stan Williams (1-1) L: Earl Wilson (14-9) S: Sonny Siebert (2) | Third | 4 out |
| Sunday, August 6 |
| » Defeated Indians (49-58), 7-3 | Cleveland Stadium (6-2) | 57-48 | |
| » W: Joe Sparma (12-4) L: George Culver (7-2) | Fourth | 3 out |
| » Lost to Indians (50-58), 6-3 | Cleveland Stadium (6-3) | 57-49 | |
| » W: Steve Hargan (12-8) L: Pat Dobson (0-2) S: Orlando Pena (4) | Fourth | 3 out |
| Tuesday, August 8 |
| » Defeated White Sox (59-46), 2-1 | Tiger Stadium (31-17) | 58-49 | |
| » W: Denny McLain (14-12) L: Hoyt Wilhelm (6-2) | Fourth | 3 out |
| » Lost to White Sox (60-46), 6-4 | Tiger Stadium (31-18) | 58-50 | |
| » W: Don McMahon (2-2) L: Dave Wickersham (4-3) S: Wilbur Wood (4) | Fourth | 3 out |
| » Major-league debuts: Rich Morales (White Sox) |
| Wednesday, August 9 |
| » Defeated White Sox (60-47), 4-2 | Tiger Stadium (32-18) | 59-50 | |
| » W: Earl Wilson (15-9) L: Fred Klages (0-2) | Third | 2 out |
| Thursday, August 10 |
| » Lost to White Sox (61-47), 2-1 | Tiger Stadium (32-19) | 59-51 | |
| » W: Hoyt Wilhelm (7-2) L: Mike Marshall (1-2) S: Bob Locker (12) | Fourth | 3 out |
| Friday, August 11 |
| » Lost to Orioles (50-60), 5-1 | Tiger Stadium (32-20) | 59-52 | Lost 2 |
| » W: Tom Phoebus (10-7) L: Dave Wickersham (4-4) S: Stu Miller (5) | Fourth | 2½ out |
| » Defeated Orioles (50-61), 5-2 | Tiger Stadium (33-20) | 60-52 | |
| » W: Mickey Lolich (6-12) L: Pete Richert (6-12) | Fourth | 2½ out |
| Saturday, August 12 |
| » Defeated Orioles (50-62), 5-4 | Tiger Stadium (34-20) | 61-52 | Won 2 |
| » W: Denny McLain (15-12) L: Gene Brabender (1-3) S: John Hiller (3) | Third | 1½ out |
| Sunday, August 13 |
| » Defeated Orioles (50-63), 3-2 | Tiger Stadium (35-20) | 62-52 | Won 3 |
| » W: Earl Wilson (16-9) L: Jim Hardin (1-1) S: Fred Lasher (1) | Third | 1 out |
| Monday, August 14 |
| » Major-league debuts: Moose Stubing (Angels) |
| Tuesday, August 15 |
| » Lost to Red Sox (61-53), 4-0 | Fenway Park (2-5) | 62-53 | |
| » W: Dave Morehead (2-2) L: Joe Sparma (12-5) | Third | 2½ out |
| Wednesday, August 16 |
| » Lost to Red Sox (62-53), 8-3 | Fenway Park (2-6) | 62-54 | Lost 2 |
| » W: Bucky Brandon (5-9) L: Denny McLain (15-13) | Fourth | 3½ out |
| Thursday, August 17 |
| » Defeated Red Sox (62-54), 7-4 | Fenway Park (3-6) | 63-54 | |
| » W: Fred Gladding (4-4) L: Sparky Lyle (1-1) | Third | 3 out |
| Friday, August 18 |
| » Defeated Indians (57-63), 4-0 | Tiger Stadium (36-20) | 64-54 | Won 2 |
| » W: Mickey Lolich (7-12) L: Sam McDowell (10-10) | Third | 2½ out |
| Saturday, August 19 |
| » Lost to Indians (58-63), 5-0 | Tiger Stadium (36-21) | 64-55 | |
| » W: John O'Donoghue (7-5) L: Joe Sparma (12-6) | Fourth | 3½ out |
| Sunday, August 20 |
| » Defeated Indians (58-64), 4-2 | Tiger Stadium (37-21) | 65-55 | |
| » W: Denny McLain (16-13) L: Stan Williams (3-2) S: Fred Lasher (2) | Fourth | 2 out |
| » Defeated Indians (58-65), 4-0 | Tiger Stadium (38-21) | 66-55 | Won 2 |
| » W: John Hiller (2-0) L: Sam McDowell (10-11) | Fourth | 2 out |
| Tuesday, August 22 |
| » Defeated Twins (67-53), 7-3 | Tiger Stadium (39-21) | 67-55 | Won 3 |
| » W: Earl Wilson (17-9) L: Dean Chance (16-9) | Fourth | 1 out |
| » Defeated Twins (67-54), 2-1 | Tiger Stadium (40-21) | 68-55 | Won 4 |
| » W: Fred Lasher (1-0) L: Al Worthington (7-8) | Fourth | 1 out |
| Wednesday, August 23 |
| » Defeated Twins (67-55), 10-0 | Tiger Stadium (41-21) | 69-55 | Won 5 |
| » W: Joe Sparma (13-6) L: Jim Merritt (9-4) | Fourth | 1½ out |
| » Lost to Twins (68-55), 4-3 | Tiger Stadium (41-22) | 69-56 | |
| » W: Jim Perry (6-6) L: Dave Wickersham (4-5) S: Ron Kline (5) | Fourth | 1½ out |
| Thursday, August 24 |
| » Lost to Twins (69-55), 4-2 | Tiger Stadium (41-23) | 69-57 | Lost 2 |
| » W: Al Worthington (8-8) L: Denny McLain (16-14) | Fourth | 1½ out |
| Friday, August 25 |
| » Defeated Athletics (53-73), 3-0 | Municipal Stadium (5-2) | 70-57 | |
| » W: John Hiller (3-0) L: Chuck Dobson (8-8) | Fourth | 1½ out |
| Saturday, August 26 |
| » Defeated Athletics (53-74), 5-2 | Municipal Stadium (6-2) | 71-57 | Won 2 |
| » W: Earl Wilson (18-9) L: Catfish Hunter (11-13) | Fourth | 1 out |
| Sunday, August 27 |
| » Lost to Athletics (54-74), 2-1 | Municipal Stadium (6-3) | 71-58 | |
| » W: Roberto Rodriguez (1-0) L: Joe Sparma (13-7) S: Paul Lindblad (4) | Fourth | 1½ out |
| Monday, August 28 |
| » Defeated Angels (65-63), 10-0 | Anaheim Stadium (2-4) | 72-58 | |
| » W: Mickey Lolich (8-12) L: Jack Hamilton (9-4) | Third | 1½ out |
| Tuesday, August 29 |
| » Defeated Angels (65-64), 4-2 | Anaheim Stadium (3-4) | 73-58 | Won 2 |
| » W: Denny McLain (17-14) L: George Brunet (11-17) | Third | ½ out |
| » Defeated Angels (65-65), 2-1 | Anaheim Stadium (4-4) | 74-58 | Won 3 |
| » W: John Hiller (4-0) L: Rickey Clark (9-10) S: Fred Lasher (3) | Third | ½ out |
| Wednesday, August 30 |
| » Lost to Angels (66-65), 3-2 | Anaheim Stadium (4-5) | 74-59 | |
| » W: Bill Kelso (5-3) L: Earl Wilson (18-10) | Third | 1½ out |
| Friday, September 1 |
| » Lost to Twins (75-58), 5-4 | Metropolitan Stadium (2-5) | 74-60 | Lost 2 |
| » W: Jim Kaat (10-13) L: Joe Sparma (13-8) | Third | 2 out |
| Saturday, September 2 |
| » Lost to Twins (76-58), 5-0 | Metropolitan Stadium (2-6) | 74-61 | Lost 3 |
| » W: Dave Boswell (12-9) L: Denny McLain (17-15) | Fourth | 2½ out |
| » Major-league debuts: Tommy Matchick (Tigers) |
| Sunday, September 3 |
| » Defeated Twins (76-59), 5-0 | Metropolitan Stadium (3-6) | 75-61 | |
| » W: Earl Wilson (19-10) L: Dean Chance (17-11) S: Fred Lasher (4) | Fourth | 1½ out |
| Future Tiger Luis Gonzalez is born in Tampa, FL. |
| Monday, September 4 |
| » Defeated Athletics (56-79), 8-4 | Tiger Stadium (42-23) | 76-61 | Won 2 |
| » W: Mickey Lolich (9-12) L: Jim Nash (11-14) S: Fred Gladding (10) | Fourth | 1½ out |
| » Lost to Athletics (57-79), 4-2 | Tiger Stadium (42-24) | 76-62 | |
| » W: Tony Pierce (3-1) L: John Hiller (4-1) S: Paul Lindblad (5) | Fourth | 1½ out |
| Former Tiger Clyde Manion dies in Detroit, MI at the age of 71. |
| Tuesday, September 5 |
| » Defeated Athletics (57-80), 4-0 | Tiger Stadium (43-24) | 77-62 | |
| » W: Joe Sparma (14-8) L: Chuck Dobson (8-9) | Fourth | 1½ out |
| Wednesday, September 6 |
| » Defeated Athletics (57-81), 8-5 | Tiger Stadium (44-24) | 78-62 | Won 2 |
| » W: Fred Gladding (5-4) L: Lew Krausse (7-15) S: Fred Lasher (5) | Second | 1 out |
| » Defeated Athletics (57-82), 6-3 | Tiger Stadium (45-24) | 79-62 | Won 3 |
| » W: Earl Wilson (20-10) L: Paul Lindblad (5-8) | Second | 1 out |
| Friday, September 8 |
| » Defeated White Sox (78-62), 4-1 | Comiskey Park I (3-3) | 80-62 | Won 4 |
| » W: Mickey Lolich (10-12) L: Tommy John (9-10) S: Fred Lasher (6) | First | -- |
| Saturday, September 9 |
| » Defeated White Sox (78-63), 7-3 | Comiskey Park I (4-3) | 81-62 | Won 5 |
| » W: Pat Dobson (1-2) L: Bob Locker (6-4) | First | -- |
| » Major-league debuts: Roger Nelson (White Sox) |
| Sunday, September 10 |
| » Lost to White Sox (79-63), 6-0 | Comiskey Park I (4-4) | 81-63 | |
| » W: Joe Horlen (16-6) L: Joe Sparma (14-9) | Third | 1½ out |
| » Lost to White Sox (80-63), 4-0 | Comiskey Park I (4-5) | 81-64 | Lost 2 |
| » W: Cisco Carlos (1-0) L: Denny McLain (17-16) S: Bob Locker (17) | Third | 1½ out |
| Tuesday, September 12 |
| » Defeated Orioles (64-80), 6-4 | Tiger Stadium (46-24) | 82-64 | |
| » W: Fred Gladding (6-4) L: Eddie Watt (2-5) S: Fred Lasher (7) | Second | 1 out |
| Wednesday, September 13 |
| » Defeated Orioles (64-81), 6-1 | Tiger Stadium (47-24) | 83-64 | Won 2 |
| » W: Mickey Lolich (11-12) L: Pete Richert (9-15) | Second | 1 out |
| Thursday, September 14 |
| » Major-league debuts: Cito Gaston (Braves) |
| Friday, September 15 |
| » Defeated Senators (69-78), 5-4 | Tiger Stadium (48-24) | 84-64 | Won 3 |
| » W: Fred Lasher (2-0) L: Casey Cox (7-4) | First | -- |
| Saturday, September 16 |
| » Defeated Senators (69-79), 5-4 | Tiger Stadium (49-24) | 85-64 | Won 4 |
| » W: Earl Wilson (21-10) L: Bob Priddy (3-7) S: Fred Lasher (8) | First | -- |
| Sunday, September 17 |
| » Lost to |
