| Thursday, January 5 |
| Future Red Sox Chris Nabholz is born in Harrisburg, PA. |
| Friday, January 13 |
| Former Red Sox Charley Gelbert dies in Easton, PA at the age of 61. |
| Wednesday, February 1 |
| Future Red Sox Tim Naehring is born in Cincinnati, OH. |
| Saturday, February 18 |
| Future Red Sox John Valentin is born in Mineola, NY. |
| Wednesday, March 8 |
| Future Red Sox Joel Johnston is born in West Chester, PA. |
| Saturday, March 11 |
| Future Red Sox Dwayne Hosey is born in Sharon, PA. |
| Wednesday, April 12 |
| » Defeated White Sox (0-1), 5-4 | Fenway Park (1-0) | 1-0 | |
| » W: Jim Lonborg (1-0) L: John Buzhardt (0-1) S: Don McMahon (1) | First | -- |
| Thursday, April 13 |
| » Lost to White Sox (1-1), 8-5 | Fenway Park (1-1) | 1-1 | |
| » W: Jack Lamabe (1-0) L: Hank Fischer (0-1) S: Bob Locker (1) | Third | 1 out |
| Friday, April 14 |
| » Defeated Yankees (1-2), 3-0 | Yankee Stadium (1-0) | 2-1 | |
| » W: Billy Rohr (1-0) L: Whitey Ford (0-1) | Second | 1 out |
| » Major-league debuts: Thad Tillotson (Yankees) Russ Gibson and Billy Rohr (Red Sox) |
| Saturday, April 15 |
| » Lost to Yankees (2-2), 1-0 | Yankee Stadium (1-1) | 2-2 | |
| » W: Mel Stottlemyre (2-0) L: Dennis Bennett (0-1) | Third | 1 out |
| Sunday, April 16 |
| » Lost to Yankees (3-2), 7-6 | Yankee Stadium (1-2) | 2-3 | Lost 2 |
| » W: Al Downing (1-0) L: Lee Stange (0-1) | Fifth | 1½ out |
| Tuesday, April 18 |
| » Lost to White Sox (4-2), 5-2 | Comiskey Park I (0-1) | 2-4 | Lost 3 |
| » W: Bruce Howard (1-0) L: Bucky Brandon (0-1) | Seventh | 2 out |
| Friday, April 21 |
| » Defeated Yankees (4-3), 6-1 | Fenway Park (2-1) | 3-4 | |
| » W: Billy Rohr (2-0) L: Mel Stottlemyre (2-1) | Sixth | 2 out |
| Saturday, April 22 |
| » Defeated Yankees (4-4), 5-4 | Fenway Park (3-1) | 4-4 | Won 2 |
| » W: Jose Santiago (1-0) L: Dooley Womack (0-1) S: Don McMahon (2) | Third | 1 out |
| Sunday, April 23 |
| » Lost to Yankees (5-4), 7-5 | Fenway Park (3-2) | 4-5 | |
| » W: Al Downing (2-0) L: Jose Santiago (1-1) | Fifth | 1½ out |
| Future Red Sox Rheal Cormier is born in Moncton, NB. |
| Monday, April 24 |
| » Defeated Senators (4-6), 7-4 | Robert F. Kennedy Stadium (1-0) | 5-5 | |
| » W: John Wyatt (1-0) L: Dick Lines (0-1) | Fourth | 1 out |
| Tuesday, April 25 |
| » Defeated Senators (4-7), 9-3 | Robert F. Kennedy Stadium (2-0) | 6-5 | Won 2 |
| » W: Hank Fischer (1-1) L: Pete Richert (0-3) | Third | ½ out |
| Friday, April 28 |
| » Defeated Athletics (5-8), 3-0 | Fenway Park (4-2) | 7-5 | Won 3 |
| » W: Jim Lonborg (2-0) L: Catfish Hunter (2-1) | Second | ½ out |
| Saturday, April 29 |
| » Defeated Athletics (5-9), 11-10 | Fenway Park (5-2) | 8-5 | Won 4 |
| » W: Don McMahon (1-0) L: Jack Aker (2-1) | First | -- |
| Sunday, April 30 |
| » Lost to Athletics (6-9), 1-0 | Fenway Park (5-3) | 8-6 | |
| » W: Jim Nash (2-2) L: Bucky Brandon (0-2) | Third | 1 out |
| Monday, May 1 |
| » Defeated Angels (8-10), 4-0 | Anaheim Stadium (1-0) | 9-6 | |
| » W: Dennis Bennett (1-1) L: Jorge Rubio (0-2) | Second | ½ out |
| Tuesday, May 2 |
| » Lost to Angels (9-10), 3-2 | Anaheim Stadium (1-1) | 9-7 | |
| » W: Jim McGlothlin (1-0) L: Hank Fischer (1-2) | Second | 1 out |
| Wednesday, May 3 |
| » Lost to Angels (10-10), 2-1 | Anaheim Stadium (1-2) | 9-8 | Lost 2 |
| » W: Bill Kelso (2-0) L: Jim Lonborg (2-1) | Second | 1 out |
| Friday, May 5 |
| » Lost to Twins (8-10), 5-2 | Metropolitan Stadium (0-1) | 9-9 | Lost 3 |
| » W: Mudcat Grant (1-3) L: Billy Rohr (2-1) S: Al Worthington (3) | Fourth | 2 out |
| Saturday, May 6 |
| » Lost to Twins (9-10), 4-2 | Metropolitan Stadium (0-2) | 9-10 | Lost 4 |
| » W: Dean Chance (4-1) L: Bucky Brandon (0-3) | Fourth | 3 out |
| Sunday, May 7 |
| » Defeated Twins (9-11), 9-6 | Metropolitan Stadium (1-2) | 10-10 | |
| » W: Dan Osinski (1-0) L: Jim Perry (0-2) S: John Wyatt (1) | Fifth | 3 out |
| Tuesday, May 9 |
| » Lost to Athletics (9-12), 4-3 | Municipal Stadium (0-1) | 10-11 | |
| » W: Lew Krausse (1-4) L: Don McMahon (1-1) S: Jack Aker (4) | Fifth | 3½ out |
| » Defeated Athletics (9-13), 5-2 | Municipal Stadium (1-1) | 11-11 | |
| » W: John Wyatt (2-0) L: Jack Aker (2-2) S: Dan Osinski (1) | Fifth | 3½ out |
| Wednesday, May 10 |
| » Lost to Athletics (10-13), 7-4 | Municipal Stadium (1-2) | 11-12 | |
| » W: Paul Lindblad (1-0) L: Lee Stange (0-2) | Sixth | 4½ out |
| Friday, May 12 |
| » Lost to Tigers (16-7), 5-4 | Fenway Park (5-4) | 11-13 | Lost 2 |
| » W: Earl Wilson (4-2) L: Bucky Brandon (0-4) S: Fred Gladding (5) | Sixth | 5½ out |
| Saturday, May 13 |
| » Lost to Tigers (17-7), 10-8 | Fenway Park (5-5) | 11-14 | Lost 3 |
| » W: George Korince (1-0) L: John Wyatt (2-1) | Sixth | 6½ out |
| Sunday, May 14 |
| » Defeated Tigers (17-8), 8-5 | Fenway Park (6-5) | 12-14 | |
| » W: Jim Lonborg (3-1) L: Denny McLain (3-4) S: Hank Fischer (1) | Third | 6 out |
| » Defeated Tigers (17-9), 13-9 | Fenway Park (7-5) | 13-14 | Won 2 |
| » W: Jose Santiago (2-1) L: Mickey Lolich (4-2) | Third | 6 out |
| Tuesday, May 16 |
| » Lost to Orioles (12-15), 8-5 | Fenway Park (7-6) | 13-15 | |
| » W: Eddie Fisher (2-1) L: John Wyatt (2-2) S: Stu Miller (4) | Fifth | 6 out |
| Wednesday, May 17 |
| » Lost to Orioles (13-15), 12-8 | Fenway Park (7-7) | 13-16 | Lost 2 |
| » W: Bill Dillman (2-0) L: Galen Cisco (0-1) S: Moe Drabowsky (2) | Sixth | 7 out |
| Friday, May 19 |
| » Defeated Indians (13-15), 3-2 | Fenway Park (8-7) | 14-16 | |
| » W: Jim Lonborg (4-1) L: Gary Bell (1-3) | Fourth | 7 out |
| Saturday, May 20 |
| » Lost to Indians (14-15), 5-3 | Fenway Park (8-8) | 14-17 | |
| » W: Steve Bailey (1-0) L: Don McMahon (1-2) | Seventh | 7 out |
| Sunday, May 21 |
| » Defeated Indians (14-16), 4-3 | Fenway Park (9-8) | 15-17 | |
| » W: John Wyatt (3-2) L: Sonny Siebert (3-3) S: Lee Stange (1) | Fourth | 5½ out |
| » Defeated Indians (14-17), 6-2 | Fenway Park (10-8) | 16-17 | Won 2 |
| » W: Bucky Brandon (1-4) L: Sam McDowell (2-2) | Fourth | 5½ out |
| Tuesday, May 23 |
| » Defeated Tigers (21-12), 5-2 | Tiger Stadium (1-0) | 17-17 | Won 3 |
| » W: Dennis Bennett (2-1) L: Mickey Lolich (5-3) S: John Wyatt (2) | Fourth | 5 out |
| Wednesday, May 24 |
| » Defeated Tigers (21-13), 1-0 | Tiger Stadium (2-0) | 18-17 | Won 4 |
| » W: Jim Lonborg (5-1) L: Denny McLain (4-5) | Third | 5 out |
| Thursday, May 25 |
| » Lost to Tigers (22-13), 9-3 | Tiger Stadium (2-1) | 18-18 | |
| » W: Earl Wilson (6-3) L: Jose Santiago (2-2) | Fourth | 5½ out |
| Friday, May 26 |
| » Lost to Orioles (18-17), 4-3 | Memorial Stadium (0-1) | 18-19 | Lost 2 |
| » W: Moe Drabowsky (3-0) L: Billy Rohr (2-2) | Fifth | 6 out |
| Saturday, May 27 |
| » Lost to Orioles (19-17), 10-0 | Memorial Stadium (0-2) | 18-20 | Lost 3 |
| » W: Tom Phoebus (3-1) L: Bucky Brandon (1-5) | Sixth | 7 out |
| Sunday, May 28 |
| » Defeated Orioles (19-18), 4-3 | Memorial Stadium (1-2) | 19-20 | |
| » W: Jim Lonborg (6-1) L: Steve Barber (3-5) S: John Wyatt (3) | Fifth | 6 out |
| Tuesday, May 30 |
| » Defeated Angels (18-25), 5-4 | Fenway Park (11-8) | 20-20 | Won 2 |
| » W: Dan Osinski (2-0) L: Bill Kelso (2-1) S: John Wyatt (4) | Fourth | 5½ out |
| » Defeated Angels (18-26), 6-1 | Fenway Park (12-8) | 21-20 | Won 3 |
| » W: Dennis Bennett (3-1) L: George Brunet (1-8) | Fourth | 5½ out |
| Wednesday, May 31 |
| » Defeated Twins (20-22), 3-2 | Fenway Park (13-8) | 22-20 | Won 4 |
| » W: Bucky Brandon (2-5) L: Jim Perry (0-3) S: John Wyatt (5) | Third | 4½ out |
| Thursday, June 1 |
| » Lost to Twins (21-22), 4-0 | Fenway Park (13-9) | 22-21 | |
| » W: Dean Chance (9-2) L: Billy Rohr (2-3) | Fourth | 4½ out |
| Friday, June 2 |
| » Defeated Indians (22-21), 2-1 | Cleveland Stadium (1-0) | 23-21 | |
| » W: Jim Lonborg (7-1) L: Sonny Siebert (4-4) | Third | 4½ out |
| Future Red Sox Mike Stanton is born in Houston, TX. |
| Saturday, June 3 |
| » Defeated Indians (22-22), 6-2 | Cleveland Stadium (2-0) | 24-21 | Won 2 |
| » W: Dennis Bennett (4-1) L: Gary Bell (1-5) S: Jose Santiago (1) | Third | 3½ out |
| Sunday, June 4 |
| » Lost to Indians (23-22), 3-0 | Cleveland Stadium (2-1) | 24-22 | |
| » W: Steve Hargan (7-4) L: Lee Stange (0-3) | Fourth | 4 out |
| Tuesday, June 6 |
| » Lost to White Sox (27-18), 5-3 | Comiskey Park I (0-2) | 24-23 | Lost 2 |
| » W: Hoyt Wilhelm (3-1) L: Bucky Brandon (2-6) S: Wilbur Wood (1) | Fourth | 6 out |
| Thursday, June 8 |
| » Lost to White Sox (28-18), 5-2 | Comiskey Park I (0-3) | 24-24 | Lost 3 |
| » W: Joe Horlen (7-0) L: Dennis Bennett (4-2) | Fourth | 5½ out |
| » Defeated White Sox (28-19), 7-3 | Comiskey Park I (1-3) | 25-24 | |
| » W: Gary Bell (2-5) L: Bruce Howard (1-4) | Fourth | 5½ out |
| Friday, June 9 |
| » Defeated Senators (21-31), 8-7 | Fenway Park (14-9) | 26-24 | Won 2 |
| » W: Jose Santiago (3-2) L: Bob Humphreys (1-1) S: John Wyatt (6) | Fourth | 4½ out |
| Saturday, June 10 |
| » Lost to Senators (22-31), 7-3 | Fenway Park (14-10) | 26-25 | |
| » W: Camilo Pascual (6-3) L: Lee Stange (0-4) S: Dave Baldwin (4) | Fourth | 4½ out |
| Sunday, June 11 |
| » Defeated Senators (22-32), 4-3 | Fenway Park (15-10) | 27-25 | |
| » W: Jose Santiago (4-2) L: Dave Baldwin (0-1) S: John Wyatt (7) | Fourth | 5 out |
| » Lost to Senators (23-32), 8-7 | Fenway Park (15-11) | 27-26 | |
| » W: Casey Cox (1-0) L: Dan Osinski (2-1) S: Bob Priddy (1) | Fourth | 5 out |
| » Major-league debuts: Gary Waslewski (Red Sox) |
| Future Red Sox John Doherty is born in New York, NY. |
| Monday, June 12 |
| » Defeated Yankees (25-29), 3-1 | Fenway Park (16-11) | 28-26 | |
| » W: Gary Bell (3-5) L: Joe Verbanic (2-1) | Fourth | 4 out |
| Tuesday, June 13 |
| » Lost to Yankees (26-29), 5-3 | Fenway Park (16-12) | 28-27 | |
| » W: Fred Talbot (3-2) L: Jim Lonborg (7-2) S: Dooley Womack (5) | Fourth | 5 out |
| Wednesday, June 14 |
| » Lost to White Sox (33-21), 8-7 | Fenway Park (16-13) | 28-28 | Lost 2 |
| » W: Gary Peters (8-3) L: Dennis Bennett (4-3) S: Wilbur Wood (3) | Third | 5 out |
| » Defeated White Sox (33-22), 6-1 | Fenway Park (17-13) | 29-28 | |
| » W: Lee Stange (1-4) L: Fred Klages (0-1) | Third | 5 out |
| Thursday, June 15 |
| » Defeated White Sox (33-23), 2-1 | Fenway Park (18-13) | 30-28 | Won 2 |
| » W: John Wyatt (4-2) L: John Buzhardt (2-6) | Third | 4 out |
| Friday, June 16 |
| » Lost to Senators (26-35), 1-0 | Robert F. Kennedy Stadium (2-1) | 30-29 | |
| » W: Bob Priddy (1-3) L: Gary Bell (3-6) S: Dave Baldwin (5) | Fourth | 5 out |
| » Lost to Senators (27-35), 4-3 | Robert F. Kennedy Stadium (2-2) | 30-30 | Lost 2 |
| » W: Casey Cox (2-0) L: John Wyatt (4-3) | Fourth | 5 out |
| Saturday, June 17 |
| » Defeated Senators (27-36), 5-1 | Robert F. Kennedy Stadium (3-2) | 31-30 | |
| » W: Jim Lonborg (8-2) L: Barry Moore (3-4) | Third | 5 out |
| Sunday, June 18 |
| » Lost to Senators (28-36), 3-2 | Robert F. Kennedy Stadium (3-3) | 31-31 | |
| » W: Darold Knowles (4-5) L: Jose Santiago (4-3) | Fourth | 6½ out |
| Tuesday, June 20 |
| » Defeated Yankees (28-34), 7-1 | Yankee Stadium (2-2) | 32-31 | |
| » W: Gary Bell (4-6) L: Mel Stottlemyre (6-7) | Fourth | 5½ out |
| Wednesday, June 21 |
| » Defeated Yankees (28-35), 8-1 | Yankee Stadium (3-2) | 33-31 | Won 2 |
| » W: Jim Lonborg (9-2) L: Thad Tillotson (3-3) | Third | 6 out |
| Friday, June 23 |
| » Defeated Indians (33-33), 8-4 | Fenway Park (19-13) | 34-31 | Won 3 |
| » W: Lee Stange (2-4) L: Sonny Siebert (6-7) | Third | 5 out |
| Saturday, June 24 |
| » Lost to Indians (34-33), 3-2 | Fenway Park (19-14) | 34-32 | |
| » W: Steve Hargan (9-6) L: Bucky Brandon (2-7) | Third | 6 out |
| Sunday, June 25 |
| » Defeated Indians (34-34), 8-3 | Fenway Park (20-14) | 35-32 | |
| » W: Gary Bell (5-6) L: Luis Tiant (6-2) S: Jose Santiago (2) | Third | 5 out |
| Monday, June 26 |
| » Lost to Twins (35-33), 2-1 | Metropolitan Stadium (1-3) | 35-33 | |
| » W: Jim Kaat (5-8) L: Jim Lonborg (9-3) S: Al Worthington (10) | Third | 6 out |
| Tuesday, June 27 |
| » Defeated Twins (35-34), 3-2 | Metropolitan Stadium (2-3) | 36-33 | |
| » W: Gary Waslewski (1-0) L: Dean Chance (10-6) S: John Wyatt (8) | Third | 6 out |
| Wednesday, June 28 |
| » Lost to Twins (36-34), 3-2 | Metropolitan Stadium (2-4) | 36-34 | |
| » W: Dave Boswell (5-5) L: Lee Stange (2-5) | Third | 7 out |
| Friday, June 30 |
| » Defeated Athletics (34-41), 5-3 | Municipal Stadium (2-2) | 37-34 | |
| » W: Gary Bell (6-6) L: Jim Nash (8-7) S: John Wyatt (9) | Third | 5½ out |
| Former Red Sox Hap Myers dies in San Francisco, CA at the age of 80. |
| Saturday, July 1 |
| » Defeated Athletics (34-42), 10-2 | Municipal Stadium (3-2) | 38-34 | Won 2 |
| » W: Jim Lonborg (10-3) L: Chuck Dobson (4-5) | Second | 5½ out |
| Sunday, July 2 |
| » Defeated Athletics (34-43), 2-1 | Municipal Stadium (4-2) | 39-34 | Won 3 |
| » W: Gary Waslewski (2-0) L: Catfish Hunter (8-6) S: John Wyatt (10) | Second | 4½ out |
| Monday, July 3 |
| » Defeated Angels (39-40), 9-3 | Anaheim Stadium (2-2) | 40-34 | Won 4 |
| » W: Lee Stange (3-5) L: Jack Hamilton (3-1) | Second | 3½ out |
| » Major-league debuts: Ken Poulsen (Red Sox) |
| Tuesday, July 4 |
| » Lost to Angels (40-40), 4-3 | Anaheim Stadium (2-3) | 40-35 | |
| » W: Rickey Clark (6-6) L: Gary Bell (6-7) S: Minnie Rojas (12) | Fourth | 4½ out |
| » Major-league debuts: Sparky Lyle (Red Sox) |
| Wednesday, July 5 |
| » Lost to Angels (41-40), 4-3 | Anaheim Stadium (2-4) | 40-36 | Lost 2 |
| » W: George Brunet (6-11) L: Jose Santiago (4-4) | Fourth | 5½ out |
| Friday, July 7 |
| » Lost to Tigers (43-34), 5-4 | Tiger Stadium (2-2) | 40-37 | Lost 3 |
| » W: Mike Marshall (1-1) L: John Wyatt (4-4) | Fourth | 6 out |
| Saturday, July 8 |
| » Lost to Tigers (44-34), 2-0 | Tiger Stadium (2-3) | 40-38 | Lost 4 |
| » W: Denny McLain (10-9) L: Lee Stange (3-6) | Fifth | 7 out |
| Sunday, July 9 |
| » Lost to Tigers (45-34), 10-4 | Tiger Stadium (2-4) | 40-39 | Lost 5 |
| » W: Earl Wilson (10-7) L: Gary Bell (6-8) | Fifth | 6 out |
| » Defeated Tigers (45-35), 3-0 | Tiger Stadium (3-4) | 41-39 | |
| » W: Jim Lonborg (11-3) L: Dave Wickersham (4-2) S: John Wyatt (11) | Fifth | 6 out |
| Monday, July 10 |
| Former Red Sox Skinny Graham dies in Cambridge, MA at the age of 58. |
| Thursday, July 13 |
| » Defeated Orioles (39-44), 4-2 | Fenway Park (21-14) | 42-39 | Won 2 |
| » W: Lee Stange (4-6) L: Tom Phoebus (7-4) S: John Wyatt (12) | Fifth | 6 out |
| » Lost to Orioles (40-44), 10-0 | Fenway Park (21-15) | 42-40 | |
| » W: Dave McNally (6-5) L: Gary Bell (6-9) | Fifth | 6 out |
| Future Red Sox Pat Rapp is born in Jennings, LA. |
| Friday, July 14 |
| » Defeated Orioles (40-45), 11-5 | Fenway Park (22-15) | 43-40 | |
| » W: Jim Lonborg (12-3) L: Mike Adamson (0-1) | Fifth | 5½ out |
| Saturday, July 15 |
| » Defeated Orioles (40-46), 5-1 | Fenway Park (23-15) | 44-40 | Won 2 |
| » W: Jose Santiago (5-4) L: Pete Richert (5-10) S: Gary Bell (1) | Fifth | 4½ out |
| Sunday, July 16 |
| » Defeated Tigers (45-40), 9-5 | Fenway Park (24-15) | 45-40 | Won 3 |
| » W: Bucky Brandon (3-7) L: Joe Sparma (9-3) S: Sparky Lyle (1) | Third | 4 out |
| Monday, July 17 |
| » Defeated Tigers (45-41), 7-1 | Fenway Park (25-15) | 46-40 | Won 4 |
| » W: Lee Stange (5-6) L: Denny McLain (10-11) | Third | 3½ out |
| Tuesday, July 18 |
| » Defeated Orioles (42-47), 6-2 | Memorial Stadium (2-2) | 47-40 | Won 5 |
| » W: Jim Lonborg (13-3) L: Dave McNally (6-6) | Third | 2½ out |
| Wednesday, July 19 |
| » Defeated Orioles (42-48), 6-4 | Memorial Stadium (3-2) | 48-40 | Won 6 |
| » W: Jose Santiago (6-4) L: Pete Richert (6-11) | Third | 1½ out |
| Friday, July 21 |
| » Defeated Indians (44-48), 6-2 | Cleveland Stadium (3-1) | 49-40 | Won 7 |
| » W: Bucky Brandon (4-7) L: Luis Tiant (7-5) | Second | 1½ out |
| Former Red Sox Jimmie Foxx dies in Miami, FL at the age of 60. |
| Saturday, July 22 |
| » Defeated Indians (44-49), 4-0 | Cleveland Stadium (4-1) | 50-40 | Won 8 |
| » W: Lee Stange (6-6) L: Steve Hargan (9-8) | Second | ½ out |
| Sunday, July 23 |
| » Defeated Indians (44-50), 8-5 | Cleveland Stadium (5-1) | 51-40 | Won 9 |
| » W: Jim Lonborg (14-3) L: John O'Donoghue (5-3) | Second | ½ out |
| » Defeated Indians (44-51), 5-1 | Cleveland Stadium (6-1) | 52-40 | Won 10 |
| » W: Gary Bell (7-9) L: Luis Tiant (7-6) | Second | ½ out |
| Tuesday, July 25 |
| » Lost to Angels (54-44), 6-4 | Fenway Park (25-16) | 52-41 | |
| » W: Fred Newman (1-0) L: Gary Waslewski (2-1) | Second | 2 out |
| Future Red Sox Ed Sprague is born in Castro Valley, CA. |
| Wednesday, July 26 |
| » Defeated Angels (54-45), 9-6 | Fenway Park (26-16) | 53-41 | |
| » W: Bill Landis (1-0) L: Minnie Rojas (7-6) S: John Wyatt (13) | Second | 1½ out |
| Thursday, July 27 |
| » Defeated Angels (54-46), 6-5 | Fenway Park (27-16) | 54-41 | Won 2 |
| » W: Sparky Lyle (1-0) L: Bill Kelso (4-3) | Second | 1 out |
| Friday, July 28 |
| » Lost to Twins (51-45), 9-2 | Fenway Park (27-17) | 54-42 | |
| » W: Dean Chance (12-8) L: Jim Lonborg (14-4) | Second | 1 out |
| Saturday, July 29 |
| » Defeated Twins (51-46), 6-3 | Fenway Park (28-17) | 55-42 | |
| » W: John Wyatt (5-4) L: Al Worthington (6-6) S: Jose Santiago (3) | Second | 1½ out |
| » Lost to Twins (52-46), 10-3 | Fenway Park (28-18) | 55-43 | |
| » W: Jim Perry (3-5) L: Gary Waslewski (2-2) | Second | 1½ out |
| Sunday, July 30 |
| » Lost to Twins (53-46), 7-5 | Fenway Park (28-19) | 55-44 | Lost 2 |
| » W: Jim Merritt (7-3) L: Bucky Brandon (4-8) S: Jim Roland (2) | Second | 2 out |
| Monday, July 31 |
| » Defeated Twins (53-47), 4-0 | Fenway Park (29-19) | 56-44 | |
| » W: Lee Stange (7-6) L: Dave Boswell (8-8) | Second | 2 out |
| Tuesday, August 1 |
| » Lost to Athletics (45-59), 4-3 | Fenway Park (29-20) | 56-45 | |
| » W: Chuck Dobson (7-6) L: Dave Morehead (0-1) | Second | 2½ out |
| » Defeated Athletics (45-60), 8-3 | Fenway Park (30-20) | 57-45 | |
| » W: Jim Lonborg (15-4) L: Jack Sanford (4-4) S: Sparky Lyle (2) | Second | 2½ out |
| Wednesday, August 2 |
| » Lost to Athletics (46-60), 8-6 | Fenway Park (30-21) | 57-46 | |
| » W: Diego Segui (2-3) L: John Wyatt (5-5) S: Lew Krausse (2) | Second | 2½ out |
| Thursday, August 3 |
| » Defeated Athletics (46-61), 5-3 | Fenway Park (31-21) | 58-46 | |
| » W: Dave Morehead (1-1) L: Catfish Hunter (9-11) S: John Wyatt (14) | Second | 2 out |
| Friday, August 4 |
| » Lost to Twins (55-48), 3-0 | Metropolitan Stadium (2-5) | 58-47 | |
| » W: Jim Merritt (8-3) L: Bucky Brandon (4-9) | Second | 2½ out |
| Saturday, August 5 |
| » Lost to Twins (56-48), 2-1 | Metropolitan Stadium (2-6) | 58-48 | Lost 2 |
| » W: Dave Boswell (9-8) L: Lee Stange (7-7) | Second | 3 out |
| Sunday, August 6 |
| » Lost to Twins (57-48), 2-0 | Metropolitan Stadium (2-7) | 58-49 | Lost 3 |
| » W: Dean Chance (14-8) L: Jim Lonborg (15-5) | Third | 2½ out |
| Tuesday, August 8 |
| » Lost to Athletics (49-62), 5-3 | Municipal Stadium (4-3) | 58-50 | Lost 4 |
| » W: Catfish Hunter (10-11) L: Dave Morehead (1-2) S: Jack Aker (11) | Third | 2½ out |
| » Defeated Athletics (49-63), 7-5 | Municipal Stadium (5-3) | 59-50 | |
| » W: John Wyatt (6-5) L: Bill Stafford (0-1) S: Bucky Brandon (1) | Third | 2½ out |
| Wednesday, August 9 |
| » Defeated Athletics (49-64), 5-1 | Municipal Stadium (6-3) | 60-50 | Won 2 |
| » W: Jim Lonborg (16-5) L: Jim Nash (10-11) S: Sparky Lyle (3) | Second | 1½ out |
| Friday, August 11 |
| » Lost to Angels (60-53), 1-0 | Anaheim Stadium (2-5) | 60-51 | |
| » W: Jim McGlothlin (10-4) L: Lee Stange (7-8) | Third | 2 out |
| Saturday, August 12 |
| » Lost to Angels (61-53), 2-1 | Anaheim Stadium (2-6) | 60-52 | Lost 2 |
| » W: Jack Hamilton (8-2) L: Gary Bell (7-10) S: Minnie Rojas (20) | Fourth | 2 out |
| Sunday, August 13 |
| » Lost to Angels (62-53), 3-2 | Anaheim Stadium (2-7) | 60-53 | Lost 3 |
| » W: Rickey Clark (9-8) L: Jim Lonborg (16-6) S: Bill Kelso (8) | Fifth | 2½ out |
| » Major-league debuts: Jim Weaver (Angels) |
| Monday, August 14 |
| » Major-league debuts: Moose Stubing (Angels) |
| Tuesday, August 15 |
| » Defeated Tigers (62-53), 4-0 | Fenway Park (32-21) | 61-53 | |
| » W: Dave Morehead (2-2) L: Joe Sparma (12-5) | Fourth | 3 out |
| Wednesday, August 16 |
| » Defeated Tigers (62-54), 8-3 | Fenway Park (33-21) | 62-53 | Won 2 |
| » W: Bucky Brandon (5-9) L: Denny McLain (15-13) | Third | 3 out |
| Thursday, August 17 |
| » Lost to Tigers (63-54), 7-4 | Fenway Park (33-22) | 62-54 | |
| » W: Fred Gladding (4-4) L: Sparky Lyle (1-1) | Fourth | 3½ out |
| Former Red Sox Ray Caldwell dies in Salamanca, NY at the age of 80. |
| Friday, August 18 |
| » Defeated Angels (62-57), 3-2 | Fenway Park (34-22) | 63-54 | |
| » W: Gary Bell (8-10) L: Jack Hamilton (8-3) | Fourth | 3 out |
| Saturday, August 19 |
| » Defeated Angels (62-58), 12-11 | Fenway Park (35-22) | 64-54 | Won 2 |
| » W: Dan Osinski (3-1) L: Jim Coates (0-2) S: Jerry Stephenson (1) | Third | 3 out |
| Sunday, August 20 |
| » Defeated Angels (62-59), 12-2 | Fenway Park (36-22) | 65-54 | Won 3 |
| » W: Lee Stange (8-8) L: George Brunet (11-15) | Third | 1½ out |
| » Defeated Angels (62-60), 9-8 | Fenway Park (37-22) | 66-54 | Won 4 |
| » W: Jose Santiago (7-4) L: Minnie Rojas (9-8) | Third | 1½ out |
| Monday, August 21 |
| » Defeated Senators (59-63), 6-5 | Fenway Park (38-22) | 67-54 | Won 5 |
| » W: John Wyatt (7-5) L: Darold Knowles (5-7) | Second | 1 out |
| Tuesday, August 22 |
| » Defeated Senators (59-64), 2-1 | Fenway Park (39-22) | 68-54 | Won 6 |
| » W: Jerry Stephenson (1-0) L: Phil Ortega (9-6) S: John Wyatt (15) | Second | 1 out |
| » Defeated Senators (59-65), 5-3 | Fenway Park (40-22) | 69-54 | Won 7 |
| » W: Gary Bell (9-10) L: Casey Cox (6-2) S: Bucky Brandon (2) | Second | 1 out |
| Wednesday, August 23 |
| » Lost to Senators (60-65), 3-2 | Fenway Park (40-23) | 69-55 | |
| » W: Bob Priddy (2-5) L: Sparky Lyle (1-2) | Second | 1 out |
| Thursday, August 24 |
| » Defeated Senators (60-66), 7-5 | Fenway Park (41-23) | 70-55 | |
| » W: Dave Morehead (3-2) L: Dick Nold (0-2) S: John Wyatt (16) | Second | 1 out |
| Friday, August 25 |
| » Defeated White Sox (69-55), 7-1 | Comiskey Park I (2-3) | 71-55 | Won 2 |
| » W: Jim Lonborg (17-6) L: Gary Peters (14-7) | Third | ½ out |
| » Lost to White Sox (70-55), 2-1 | Comiskey Park I (2-4) | 71-56 | |
| » W: Bob Locker (6-3) L: John Wyatt (7-6) | Third | ½ out |
| » Major-league debuts: Cisco Carlos (White Sox) |
| Saturday, August 26 |
| » Defeated White Sox (70-56), 6-2 | Comiskey Park I (3-4) | 72-56 | |
| » W: Jerry Stephenson (2-0) L: Joe Horlen (14-5) S: Bucky Brandon (3) | First | -- |
| Sunday, August 27 |
| » Defeated White Sox (70-57), 4-3 | Comiskey Park I (4-4) | 73-56 | Won 2 |
| » W: Gary Bell (10-10) L: Fred Klages (2-3) S: John Wyatt (17) | First | -- |
| » Lost to White Sox (71-57), 1-0 | Comiskey Park I (4-5) | 73-57 | |
| » W: Gary Peters (15-7) L: Bucky Brandon (5-10) | First | -- |
| Monday, August 28 |
| » Defeated Yankees (58-72), 3-0 | Yankee Stadium (4-2) | 74-57 | |
| » W: Dave Morehead (4-2) L: Fred Talbot (5-7) S: Sparky Lyle (4) | Second | 1 out |
| Future Red Sox Darren Lewis is born in Berkeley, CA. |
| Tuesday, August 29 |
| » Defeated Yankees (58-73), 2-1 | Yankee Stadium (5-2) | 75-57 | Won 2 |
| » W: Jim Lonborg (18-6) L: Mel Stottlemyre (13-11) | First | -- |
| » Lost to Yankees (59-73), 4-3 | Yankee Stadium (5-3) | 75-58 | |
| » W: Jim Bouton (1-0) L: Bucky Brandon (5-11) | First | -- |
| Wednesday, August 30 |
| » Defeated Yankees (59-74), 2-1 | Yankee Stadium (6-3) | 76-58 | |
| » W: John Wyatt (8-6) L: Al Downing (12-8) | First | -- |
| Thursday, August 31 |
| » Lost to White Sox (73-59), 4-2 | Fenway Park (41-24) | 76-59 | |
| » W: Don McMahon (4-2) L: Gary Bell (10-11) | First | -- |
| Future Red Sox Stan Royer is born in Olney, IL. |
| Friday, September 1 |
| » Defeated White Sox (73-60), 10-2 | Fenway Park (42-24) | 77-59 | |
| » W: Jose Santiago (8-4) L: Gary Peters (15-8) | First | -- |
| » Major-league debuts: Ed Herrmann and Cotton Nash (White Sox) |
| Saturday, September 2 |
| » Lost to White Sox (74-60), 4-1 | Fenway Park (42-25) | 77-60 | |
| » W: Joe Horlen (15-6) L: Jim Lonborg (18-7) | Second | 1½ out |
| Sunday, September 3 |
| » Lost to White Sox (75-60), 4-0 | Fenway Park (42-26) | 77-61 | Lost 2 |
| » W: Tommy John (9-9) L: Lee Stange (8-9) | Second | 1½ out |
| Monday, September 4 |
| » Lost to Senators (66-72), 5-2 | Robert F. Kennedy Stadium (3-4) | 77-62 | Lost 3 |
| » W: Camilo Pascual (12-10) L: Dave Morehead (4-3) S: Darold Knowles (12) | Second | 1½ out |
| » Defeated Senators (66-73), 6-4 | Robert F. Kennedy Stadium (4-4) | 78-62 | |
| » W: Jerry Stephenson (3-0) L: Dick Lines (1-5) S: John Wyatt (18) | Second | 1½ out |
| Tuesday, September 5 |
| » Defeated Senators (66-74), 8-2 | Robert F. Kennedy Stadium (5-4) | 79-62 | Won 2 |
| » W: Gary Bell (11-11) L: Frank Bertaina (4-5) | Second | 1½ out |
| Wednesday, September 6 |
| » Major-league debuts: Pat Kelly and Graig Nettles (Twins) |
| Thursday, September 7 |
| » Defeated Yankees (62-79), 3-1 | Fenway Park (43-26) | 80-62 | Won 3 |
| » W: Jim Lonborg (19-7) L: Mel Stottlemyre (14-12) | Second | 1 out |
| Friday, September 8 |
| » Lost to Yankees (63-79), 5-2 | Fenway Park (43-27) | 80-63 | |
| » W: Bill Monbouquette (4-4) L: Lee Stange (8-10) S: Joe Verbanic (2) | Second | ½ out |
| Saturday, September 9 |
| » Defeated Yankees (63-80), 7-1 | Fenway Park (44-27) | 81-63 | |
| » W: Dave Morehead (5-3) L: Steve Barber (9-16) S: Sparky Lyle (5) | Second | ½ out |
| » Major-league debuts: Dale Roberts (Yankees) |
| Sunday, September 10 |
| » Defeated Yankees (63-81), 9-1 | Fenway Park (45-27) | 82-63 | Won 2 |
| » W: Gary Bell (12-11) L: Al Downing (13-9) | Second | ½ out |
| Tuesday, September 12 |
| » Defeated Athletics (59-85), 3-1 | Fenway Park (46-27) | 83-63 | Won 3 |
| » W: Jim Lonborg (20-7) L: Catfish Hunter (11-15) | First | -- |
| Wednesday, September 13 |
| » Defeated Athletics (59-86), 4-2 | Fenway Park (47-27) | 84-63 | Won 4 |
| » W: John Wyatt (9-6) |