| Monday, March 7 |
| Future Twin Mauro Gozzo is born in New Britain, CT. |
| Tuesday, April 12 |
| » Defeated Athletics (0-1), 2-1 | Metropolitan Stadium (1-0) | 1-0 | |
| » Starters: Catfish Hunter vs Mudcat Grant | First | -- |
| Wednesday, April 13 |
| » Defeated Athletics (0-2), 5-3 | Metropolitan Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Rollie Sheldon vs Camilo Pascual | First | -- |
| Thursday, April 14 |
| » Defeated Athletics (0-3), 4-2 | Metropolitan Stadium (3-0) | 3-0 | Won 3 |
| » Starters: Fred Talbot vs Jim Kaat | First | -- |
| Future Twin Greg Myers is born in Riverside, CA. |
| Friday, April 15 |
| » Lost to Angels (2-1), 9-4 | Metropolitan Stadium (3-1) | 3-1 | |
| » Starters: Jack Sanford vs Dave Boswell | Third | 1 out |
| Saturday, April 16 |
| » Lost to Angels (3-1), 3-2 | Metropolitan Stadium (3-2) | 3-2 | Lost 2 |
| » Starters: Dean Chance vs Mudcat Grant | Fifth | 2 out |
| Tuesday, April 19 |
| » Lost to Athletics (1-5), 3-2 | Municipal Stadium (0-1) | 3-3 | Lost 3 |
| » Starters: Camilo Pascual vs Chuck Dobson | Sixth | 2½ out |
| Thursday, April 21 |
| » Major-league debuts: Jorge Rubio (Angels) |
| Friday, April 22 |
| » Lost to Angels (5-3), 2-1 | Anaheim Stadium (0-1) | 3-4 | Lost 4 |
| » Starters: Jim Kaat vs Jim McGlothlin | Sixth | 3½ out |
| Saturday, April 23 |
| » Lost to Angels (6-3), 4-3 | Anaheim Stadium (0-2) | 3-5 | Lost 5 |
| » Starters: Mudcat Grant vs Marcelino Lopez | Sixth | 4½ out |
| Sunday, April 24 |
| » Defeated Angels (6-4), 5-3 | Anaheim Stadium (1-2) | 4-5 | |
| » Starters: Camilo Pascual vs Dean Chance | Sixth | 4 out |
| Monday, April 25 |
| » Lost to Tigers (9-4), 3-0 | Tiger Stadium (0-1) | 4-6 | |
| » Starters: Dave Boswell vs Denny McLain | Sixth | 5 out |
| Sunday, May 1 |
| » Lost to Senators (4-9), 5-3 | Robert F. Kennedy Stadium (0-1) | 4-7 | Lost 2 |
| » Starters: Jim Kaat vs Pete Richert | Sixth | 6½ out |
| » Defeated Senators (4-10), 3-1 | Robert F. Kennedy Stadium (1-1) | 5-7 | |
| » Starters: Mudcat Grant vs Mike McCormick | Sixth | 6½ out |
| Tuesday, May 3 |
| » Defeated White Sox (10-5), 4-2 | Comiskey Park I (1-0) | 6-7 | Won 2 |
| » Starters: Camilo Pascual vs Joe Horlen | Sixth | 6 out |
| Wednesday, May 4 |
| » Defeated White Sox (10-6), 6-1 | Comiskey Park I (2-0) | 7-7 | Won 3 |
| » Starters: Jim Kaat vs John Buzhardt | Sixth | 6 out |
| Friday, May 6 |
| » Defeated Red Sox (5-13), 5-4 | Metropolitan Stadium (4-2) | 8-7 | Won 4 |
| » Starters: Dick Stigman vs Dave Boswell | Sixth | 5½ out |
| Saturday, May 7 |
| » Defeated Red Sox (5-14), 6-4 | Metropolitan Stadium (5-2) | 9-7 | Won 5 |
| » Starters: Jerry Stephenson vs Camilo Pascual | Sixth | 5½ out |
| Sunday, May 8 |
| » Lost to Red Sox (6-14), 8-1 | Metropolitan Stadium (5-3) | 9-8 | |
| » Starters: Earl Wilson vs Jim Kaat | Fifth | 5½ out |
| » Lost to Red Sox (7-14), 4-1 | Metropolitan Stadium (5-4) | 9-9 | Lost 2 |
| » Starters: Jose Santiago vs Mudcat Grant | Fifth | 5½ out |
| Monday, May 9 |
| » Lost to Yankees (7-16), 3-2 | Metropolitan Stadium (5-5) | 9-10 | Lost 3 |
| » Starters: Mel Stottlemyre vs Jim Perry | Fourth | 6 out |
| Thursday, May 12 |
| » Defeated Yankees (7-17), 4-3 | Metropolitan Stadium (6-5) | 10-10 | |
| » Starters: Fritz Peterson vs Camilo Pascual | Sixth | 5 out |
| Friday, May 13 |
| » Defeated Senators (9-15), 9-5 | Metropolitan Stadium (7-5) | 11-10 | Won 2 |
| » Starters: Jim Duckworth vs Jim Kaat | Sixth | 5 out |
| Saturday, May 14 |
| » Lost to Senators (10-15), 5-4 | Metropolitan Stadium (7-6) | 11-11 | |
| » Starters: Pete Richert vs Mudcat Grant | Sixth | 6 out |
| Sunday, May 15 |
| » Defeated Senators (10-16), 6-2 | Metropolitan Stadium (8-6) | 12-11 | |
| » Starters: Mike McCormick vs Jim Perry | Sixth | 5½ out |
| Monday, May 16 |
| » Defeated Senators (10-17), 2-1 | Metropolitan Stadium (9-6) | 13-11 | Won 2 |
| » Starters: Phil Ortega vs Camilo Pascual | Sixth | 5 out |
| Tuesday, May 17 |
| » Defeated White Sox (14-12), 8-3 | Metropolitan Stadium (10-6) | 14-11 | Won 3 |
| » Starters: Joe Horlen vs Jim Kaat | Fifth | 5 out |
| Wednesday, May 18 |
| » Defeated White Sox (14-13), 7-1 | Metropolitan Stadium (11-6) | 15-11 | Won 4 |
| » Starters: Gary Peters vs Mudcat Grant | Fourth | 4 out |
| Thursday, May 19 |
| » Defeated White Sox (14-14), 4-3 | Metropolitan Stadium (12-6) | 16-11 | Won 5 |
| » Starters: John Buzhardt vs Jim Perry | Fourth | 3 out |
| Friday, May 20 |
| » Lost to Yankees (12-19), 2-1 | Yankee Stadium (0-1) | 16-12 | |
| » Starters: Camilo Pascual vs Al Downing | Fourth | 4 out |
| Saturday, May 21 |
| » Lost to Yankees (13-19), 4-2 | Yankee Stadium (0-2) | 16-13 | Lost 2 |
| » Starters: Jim Kaat vs Bob Friend | Fourth | 4 out |
| Sunday, May 22 |
| » Lost to Yankees (14-19), 5-3 | Yankee Stadium (0-3) | 16-14 | Lost 3 |
| » Starters: Mudcat Grant vs Mel Stottlemyre | Fourth | 6 out |
| » Lost to Yankees (15-19), 2-1 | Yankee Stadium (0-4) | 16-15 | Lost 4 |
| » Starters: Jim Merritt vs Fritz Peterson | Fourth | 6 out |
| Tuesday, May 24 |
| » Lost to Red Sox (14-21), 11-2 | Fenway Park (0-1) | 16-16 | Lost 5 |
| » Starters: Camilo Pascual vs Jose Santiago | Fifth | 6½ out |
| Wednesday, May 25 |
| » Defeated Red Sox (14-22), 7-5 | Fenway Park (1-1) | 17-16 | |
| » Starters: Jim Kaat vs Jerry Stephenson | Fourth | 6½ out |
| Future Twin Dave Hollins is born in Buffalo, NY. |
| Thursday, May 26 |
| » Lost to Red Sox (15-22), 7-2 | Fenway Park (1-2) | 17-17 | |
| » Starters: Mudcat Grant vs Earl Wilson | Fourth | 7½ out |
| Friday, May 27 |
| » Lost to Indians (26-10), 5-4 | Cleveland Stadium (0-1) | 17-18 | Lost 2 |
| » Starters: Camilo Pascual vs John O'Donoghue | Fifth | 8½ out |
| Saturday, May 28 |
| » Lost to Indians (27-10), 2-1 | Cleveland Stadium (0-2) | 17-19 | Lost 3 |
| » Starters: Dave Boswell vs Gary Bell | Fifth | 9½ out |
| Future Twin Mike Maksudian is born in Belleville, IL. |
| Sunday, May 29 |
| » Defeated Indians (27-11), 5-1 | Cleveland Stadium (1-2) | 18-19 | |
| » Starters: Jim Kaat vs Tom Kelley | Fifth | 7½ out |
| » Defeated Indians (27-12), 1-0 | Cleveland Stadium (2-2) | 19-19 | Won 2 |
| » Starters: Mudcat Grant vs Luis Tiant | Fifth | 7½ out |
| Monday, May 30 |
| » Lost to Orioles (24-16), 5-1 | Metropolitan Stadium (12-7) | 19-20 | |
| » Starters: Steve Barber vs Jim Merritt | Fifth | 6½ out |
| » Defeated Orioles (24-17), 7-4 | Metropolitan Stadium (13-7) | 20-20 | |
| » Starters: Frank Bertaina vs Dwight Siebler | Fifth | 6½ out |
| Tuesday, May 31 |
| » Lost to Orioles (25-17), 14-5 | Metropolitan Stadium (13-8) | 20-21 | |
| » Starters: Dave McNally vs Camilo Pascual | Fifth | 7½ out |
| Wednesday, June 1 |
| » Lost to Tigers (24-18), 9-4 | Metropolitan Stadium (13-9) | 20-22 | Lost 2 |
| » Starters: Dave Wickersham vs Dave Boswell | Sixth | 7½ out |
| Thursday, June 2 |
| » Lost to Tigers (25-18), 7-6 | Metropolitan Stadium (13-10) | 20-23 | Lost 3 |
| » Starters: Mickey Lolich vs Jim Kaat | Seventh | 7½ out |
| Friday, June 3 |
| » Lost to Indians (29-16), 6-5 | Metropolitan Stadium (13-11) | 20-24 | Lost 4 |
| » Starters: Luis Tiant vs Mudcat Grant | Seventh | 8½ out |
| Saturday, June 4 |
| » Lost to Indians (30-16), 7-4 | Metropolitan Stadium (13-12) | 20-25 | Lost 5 |
| » Starters: Tom Kelley vs Camilo Pascual | Seventh | 9½ out |
| » Major-league debuts: Buddy Booker (Indians) |
| Sunday, June 5 |
| » Defeated Indians (30-17), 9-4 | Metropolitan Stadium (14-12) | 21-25 | |
| » Starters: Sonny Siebert vs Dave Boswell | Sixth | 8½ out |
| Tuesday, June 7 |
| » Defeated Athletics (18-29), 6-1 | Metropolitan Stadium (15-12) | 22-25 | Won 2 |
| » Starters: Rollie Sheldon vs Jim Kaat | Sixth | 7½ out |
| Wednesday, June 8 |
| » Lost to Athletics (19-29), 5-4 | Metropolitan Stadium (15-13) | 22-26 | |
| » Starters: Fred Talbot vs Mudcat Grant | Sixth | 9 out |
| Thursday, June 9 |
| » Defeated Athletics (19-30), 9-4 | Metropolitan Stadium (16-13) | 23-26 | |
| » Starters: Catfish Hunter vs Camilo Pascual | Sixth | 9 out |
| Friday, June 10 |
| » Defeated White Sox (25-25), 6-2 | Comiskey Park I (3-0) | 24-26 | Won 2 |
| » Starters: Dave Boswell vs John Buzhardt | Sixth | 9 out |
| Saturday, June 11 |
| » Defeated White Sox (25-26), 4-3 | Comiskey Park I (4-0) | 25-26 | Won 3 |
| » Starters: Jim Kaat vs Gary Peters | Fifth | 8 out |
| Sunday, June 12 |
| » Defeated White Sox (25-27), 2-1 | Comiskey Park I (5-0) | 26-26 | Won 4 |
| » Starters: Mudcat Grant vs Tommy John | Fourth | 8 out |
| Monday, June 13 |
| » Lost to Athletics (22-31), 5-2 | Municipal Stadium (0-2) | 26-27 | |
| » Starters: Camilo Pascual vs Catfish Hunter | Fourth | 8 out |
| » Defeated Athletics (22-32), 6-1 | Municipal Stadium (1-2) | 27-27 | |
| » Starters: Jim Perry vs Paul Lindblad | Fourth | 8 out |
| Tuesday, June 14 |
| » Defeated Athletics (22-33), 6-3 | Municipal Stadium (2-2) | 28-27 | Won 2 |
| » Starters: Dave Boswell vs Chuck Dobson | Fourth | 8½ out |
| Wednesday, June 15 |
| » Lost to Angels (30-29), 8-1 | Metropolitan Stadium (16-14) | 28-28 | |
| » Starters: Clyde Wright vs Jim Kaat | Fifth | 10 out |
| » Lost to Angels (31-29), 6-3 | Metropolitan Stadium (16-15) | 28-29 | Lost 2 |
| » Starters: Jim McGlothlin vs Camilo Pascual | Fifth | 10 out |
| » Major-league debuts: Clyde Wright (Angels) |
| Thursday, June 16 |
| » Lost to Angels (32-29), 7-2 | Metropolitan Stadium (16-16) | 28-30 | Lost 3 |
| » Starters: George Brunet vs Mudcat Grant | Fifth | 10 out |
| Friday, June 17 |
| » Lost to White Sox (29-30), 3-1 | Metropolitan Stadium (16-17) | 28-31 | Lost 4 |
| » Starters: Tommy John vs Jim Perry | Sixth | 11 out |
| Saturday, June 18 |
| » Defeated White Sox (29-31), 9-8 | Metropolitan Stadium (17-17) | 29-31 | |
| » Starters: Jack Lamabe vs Dave Boswell | Fifth | 11 out |
| Sunday, June 19 |
| » Defeated White Sox (29-32), 6-4 | Metropolitan Stadium (18-17) | 30-31 | Won 2 |
| » Starters: Gary Peters vs Jim Kaat | Fifth | 10½ out |
| Monday, June 20 |
| » Lost to Angels (35-31), 5-3 | Anaheim Stadium (1-3) | 30-32 | |
| » Starters: Mudcat Grant vs George Brunet | Fifth | 11 out |
| Tuesday, June 21 |
| » Lost to Angels (36-31), 10-7 | Anaheim Stadium (1-4) | 30-33 | Lost 2 |
| » Starters: Jim Perry vs Marcelino Lopez | Fifth | 11½ out |
| Wednesday, June 22 |
| » Lost to Angels (37-31), 4-1 | Anaheim Stadium (1-5) | 30-34 | Lost 3 |
| » Starters: Dave Boswell vs Dean Chance | Sixth | 12½ out |
| Friday, June 24 |
| » Lost to Tigers (42-23), 2-1 | Tiger Stadium (0-2) | 30-35 | Lost 4 |
| » Starters: Jim Kaat vs Dave Wickersham | Fifth | 12½ out |
| » Defeated Tigers (42-24), 9-2 | Tiger Stadium (1-2) | 31-35 | |
| » Starters: Camilo Pascual vs Hank Aguirre | Fifth | 12½ out |
| Saturday, June 25 |
| » Lost to Tigers (43-24), 1-0 | Tiger Stadium (1-3) | 31-36 | |
| » Starters: Mudcat Grant vs Denny McLain | Sixth | 13½ out |
| Sunday, June 26 |
| » Defeated Tigers (43-25), 7-5 | Tiger Stadium (2-3) | 32-36 | |
| » Starters: Dave Boswell vs Joe Sparma | Fifth | 13 out |
| » Defeated Tigers (43-26), 7-1 | Tiger Stadium (3-3) | 33-36 | Won 2 |
| » Starters: Jim Perry vs Mickey Lolich | Fifth | 13 out |
| Monday, June 27 |
| » Defeated Indians (41-28), 6-2 | Metropolitan Stadium (19-17) | 34-36 | Won 3 |
| » Starters: Luis Tiant vs Jim Kaat | Fifth | 13 out |
| Tuesday, June 28 |
| » Defeated Indians (41-29), 4-0 | Metropolitan Stadium (20-17) | 35-36 | Won 4 |
| » Starters: John O'Donoghue vs Camilo Pascual | Fifth | 12 out |
| Wednesday, June 29 |
| » Lost to Indians (42-29), 4-1 | Metropolitan Stadium (20-18) | 35-37 | |
| » Starters: Gary Bell vs Mudcat Grant | Fifth | 13 out |
| Thursday, June 30 |
| » Lost to Indians (43-29), 4-0 | Metropolitan Stadium (20-19) | 35-38 | Lost 2 |
| » Starters: Steve Hargan vs Jim Perry | Fifth | 14 out |
| Friday, July 1 |
| » Lost to Orioles (51-25), 4-1 | Memorial Stadium (0-1) | 35-39 | Lost 3 |
| » Starters: Jim Kaat vs Steve Barber | Sixth | 16 out |
| » Lost to Orioles (52-25), 2-0 | Memorial Stadium (0-2) | 35-40 | Lost 4 |
| » Starters: Jim Merritt vs Bill Short | Sixth | 16 out |
| Saturday, July 2 |
| » Lost to Orioles (53-25), 6-5 | Memorial Stadium (0-3) | 35-41 | Lost 5 |
| » Starters: Dave Boswell vs John Miller | Sixth | 18 out |
| » Lost to Orioles (54-25), 3-2 | Memorial Stadium (0-4) | 35-42 | Lost 6 |
| » Starters: Mudcat Grant vs Eddie Watt | Sixth | 18 out |
| Sunday, July 3 |
| » Lost to Orioles (55-25), 4-2 | Memorial Stadium (0-5) | 35-43 | Lost 7 |
| » Starters: Jim Perry vs Dave McNally | Seventh | 19 out |
| Monday, July 4 |
| » Defeated Indians (45-32), 5-4 | Cleveland Stadium (3-2) | 36-43 | |
| » Starters: Jim Kaat vs Gary Bell | Sixth | 18 out |
| Tuesday, July 5 |
| » Defeated Indians (45-33), 4-3 | Cleveland Stadium (4-2) | 37-43 | Won 2 |
| » Starters: Jim Merritt vs Tom Kelley | Sixth | 17½ out |
| Wednesday, July 6 |
| » Defeated Indians (45-34), 4-3 | Cleveland Stadium (5-2) | 38-43 | Won 3 |
| » Starters: Dave Boswell vs Sam McDowell | Fifth | 17 out |
| Thursday, July 7 |
| » Lost to Tigers (47-33), 4-3 | Metropolitan Stadium (20-20) | 38-44 | |
| » Starters: Dave Wickersham vs Mudcat Grant | Sixth | 17½ out |
| Friday, July 8 |
| » Defeated Tigers (47-34), 6-1 | Metropolitan Stadium (21-20) | 39-44 | |
| » Starters: Mickey Lolich vs Jim Kaat | Fifth | 17½ out |
| Saturday, July 9 |
| » Lost to Tigers (48-34), 8-1 | Metropolitan Stadium (21-21) | 39-45 | |
| » Starters: Denny McLain vs Jim Merritt | Fifth | 18 out |
| Sunday, July 10 |
| » Defeated Tigers (48-35), 4-2 | Metropolitan Stadium (22-21) | 40-45 | |
| » Starters: Earl Wilson vs Dave Boswell | Fifth | 17 out |
| Thursday, July 14 |
| » Defeated Senators (39-50), 3-1 | Metropolitan Stadium (23-21) | 41-45 | Won 2 |
| » Starters: Phil Ortega vs Mudcat Grant | Fifth | 16 out |
| Friday, July 15 |
| » Defeated Senators (39-51), 5-4 | Metropolitan Stadium (24-21) | 42-45 | Won 3 |
| » Starters: Mike McCormick vs Jim Kaat | Fifth | 15 out |
| Future Twin Brett Merriman is born in Jacksonville, IL. |
| Saturday, July 16 |
| » Defeated Senators (39-52), 6-2 | Metropolitan Stadium (25-21) | 43-45 | Won 4 |
| » Starters: Diego Segui vs Dave Boswell | Fifth | 15 out |
| Sunday, July 17 |
| » Lost to Yankees (39-49), 4-2 | Metropolitan Stadium (25-22) | 43-46 | |
| » Starters: Fred Talbot vs Jim Merritt | Fifth | 16 out |
| » Lost to Yankees (40-49), 9-6 | Metropolitan Stadium (25-23) | 43-47 | Lost 2 |
| » Starters: Jim Bouton vs Jim Perry | Fifth | 16 out |
| Monday, July 18 |
| » Lost to Yankees (41-49), 6-4 | Metropolitan Stadium (25-24) | 43-48 | Lost 3 |
| » Starters: Al Downing vs Mudcat Grant | Fifth | 17 out |
| Tuesday, July 19 |
| » Defeated Senators (40-54), 5-4 | Robert F. Kennedy Stadium (2-1) | 44-48 | |
| » Starters: Jim Kaat vs Pete Richert | Fifth | 16½ out |
| » Defeated Senators (40-55), 4-0 | Robert F. Kennedy Stadium (3-1) | 45-48 | Won 2 |
| » Starters: Jim Perry vs Phil Ortega | Fifth | 16½ out |
| Wednesday, July 20 |
| » Defeated Senators (40-56), 3-1 | Robert F. Kennedy Stadium (4-1) | 46-48 | Won 3 |
| » Starters: Dave Boswell vs Mike McCormick | Fifth | 16½ out |
| Thursday, July 21 |
| » Defeated Senators (40-57), 1-0 | Robert F. Kennedy Stadium (5-1) | 47-48 | Won 4 |
| » Starters: Jim Merritt vs Jim Hannan | Fifth | 16½ out |
| Friday, July 22 |
| » Lost to Red Sox (42-56), 6-5 | Fenway Park (1-3) | 47-49 | |
| » Starters: Mudcat Grant vs Lee Stange | Fifth | 17½ out |
| Saturday, July 23 |
| » Defeated Red Sox (42-57), 10-4 | Fenway Park (2-3) | 48-49 | |
| » Starters: Jim Kaat vs Rollie Sheldon | Fifth | 17½ out |
| Sunday, July 24 |
| » Defeated Red Sox (42-58), 4-2 | Fenway Park (3-3) | 49-49 | Won 2 |
| » Starters: Jim Perry vs Bucky Brandon | Fifth | 16½ out |
| Tuesday, July 26 |
| » Defeated Yankees (45-52), 6-3 | Yankee Stadium (1-4) | 50-49 | Won 3 |
| » Starters: Dave Boswell vs Fritz Peterson | Fifth | 15½ out |
| Wednesday, July 27 |
| » Lost to Yankees (46-52), 6-3 | Yankee Stadium (1-5) | 50-50 | |
| » Starters: Jim Kaat vs Fred Talbot | Fifth | 16½ out |
| Thursday, July 28 |
| Future Twin Derek Lee is born in Chicago, IL. |
| Friday, July 29 |
| » Lost to Orioles (68-34), 3-0 | Metropolitan Stadium (25-25) | 50-51 | Lost 2 |
| » Starters: Jim Palmer vs Jim Merritt | Fifth | 17½ out |
| Saturday, July 30 |
| » Defeated Orioles (68-35), 7-0 | Metropolitan Stadium (26-25) | 51-51 | |
| » Starters: Bill Short vs Dave Boswell | Fifth | 16½ out |
| Sunday, July 31 |
| » Lost to Orioles (69-35), 4-0 | Metropolitan Stadium (26-26) | 51-52 | |
| » Starters: Eddie Watt vs Jim Kaat | Fifth | 17½ out |
| Monday, August 1 |
| » Defeated Red Sox (45-62), 6-2 | Metropolitan Stadium (27-26) | 52-52 | |
| » Starters: Lee Stange vs Mudcat Grant | Fifth | 17 out |
| Tuesday, August 2 |
| » Defeated Red Sox (45-63), 7-3 | Metropolitan Stadium (28-26) | 53-52 | Won 2 |
| » Starters: Bucky Brandon vs Jim Perry | Fifth | 17 out |
| Wednesday, August 3 |
| » Defeated Red Sox (45-64), 7-2 | Metropolitan Stadium (29-26) | 54-52 | Won 3 |
| » Starters: Rollie Sheldon vs Dave Boswell | Fifth | 16 out |
| Thursday, August 4 |
| » Defeated Red Sox (45-65), 2-1 | Metropolitan Stadium (30-26) | 55-52 | Won 4 |
| » Starters: Jose Santiago vs Jim Kaat | Fifth | 15 out |
| Friday, August 5 |
| » Lost to Athletics (48-59), 4-2 | Municipal Stadium (2-3) | 55-53 | |
| » Starters: Jim Merritt vs Gil Blanco | Fifth | 15 out |
| Saturday, August 6 |
| » Defeated Athletics (48-60), 5-0 | Municipal Stadium (3-3) | 56-53 | |
| » Starters: Mudcat Grant vs Lew Krausse | Fifth | 15 out |
| Sunday, August 7 |
| » Defeated Athletics (48-61), 2-1 | Municipal Stadium (4-3) | 57-53 | Won 2 |
| » Starters: Dave Boswell vs Blue Moon Odom | Fifth | 14½ out |
| » Lost to Athletics (49-61), 4-2 | Municipal Stadium (4-4) | 57-54 | |
| » Starters: Jim Perry vs Paul Lindblad | Fifth | 14½ out |
| Monday, August 8 |
| » Lost to Athletics (50-61), 6-1 | Municipal Stadium (4-5) | 57-55 | Lost 2 |
| » Starters: Jim Kaat vs Jim Nash | Fifth | 15 out |
| Tuesday, August 9 |
| » Lost to Angels (58-53), 2-0 | Anaheim Stadium (1-6) | 57-56 | Lost 3 |
| » Starters: Jim Merritt vs Marcelino Lopez | Sixth | 15 out |
| Wednesday, August 10 |
| » Defeated Angels (58-54), 2-0 | Anaheim Stadium (2-6) | 58-56 | |
| » Starters: Mudcat Grant vs Clyde Wright | Fifth | 15 out |
| Thursday, August 11 |
| » Defeated Angels (58-55), 4-3 | Anaheim Stadium (3-6) | 59-56 | Won 2 |
| » Starters: Jim Kaat vs George Brunet | Fourth | 15 out |
| Friday, August 12 |
| » Defeated Athletics (50-65), 6-2 | Metropolitan Stadium (31-26) | 60-56 | Won 3 |
| » Starters: Paul Lindblad vs Jim Perry | Fifth | 14½ out |
| Sunday, August 14 |
| » Lost to Athletics (51-65), 5-0 | Metropolitan Stadium (31-27) | 60-57 | |
| » Starters: Jim Nash vs Mudcat Grant | Fifth | 16½ out |
| » Lost to Athletics (52-65), 4-3 | Metropolitan Stadium (31-28) | 60-58 | Lost 2 |
| » Starters: Gil Blanco vs Jim Merritt | Fifth | 16½ out |
| Monday, August 15 |
| » Defeated Angels (60-58), 5-3 | Metropolitan Stadium (32-28) | 61-58 | |
| » Starters: George Brunet vs Jim Kaat | Fifth | 16½ out |
| Tuesday, August 16 |
| » Defeated Angels (60-59), 8-1 | Metropolitan Stadium (33-28) | 62-58 | Won 2 |
| » Starters: Dean Chance vs Jim Perry | Fourth | 16½ out |
| Wednesday, August 17 |
| » Defeated Angels (60-60), 5-3 | Metropolitan Stadium (34-28) | 63-58 | Won 3 |
| » Starters: Fred Newman vs Camilo Pascual | Fourth | 16½ out |
| Thursday, August 18 |
| » Defeated Angels (60-61), 6-2 | Metropolitan Stadium (35-28) | 64-58 | Won 4 |
| » Starters: Marcelino Lopez vs Mudcat Grant | Fourth | 16 out |
| Friday, August 19 |
| » Defeated Red Sox (53-73), 2-1 | Fenway Park (4-3) | 65-58 | Won 5 |
| » Starters: Jim Kaat vs Lee Stange | Fourth | 15 out |
| Saturday, August 20 |
| » Defeated Red Sox (53-74), 4-2 | Fenway Park (5-3) | 66-58 | Won 6 |
| » Starters: Jim Perry vs Dennis Bennett | Third | 15 out |
| Sunday, August 21 |
| » Lost to Red Sox (54-74), 6-4 | Fenway Park (5-4) | 66-59 | |
| » Starters: Dave Boswell vs Jim Lonborg | Third | 15 out |
| Tuesday, August 23 |
| » Defeated Senators (56-73), 7-0 | Robert F. Kennedy Stadium (6-1) | 67-59 | |
| » Starters: Jim Kaat vs Pete Richert | Fourth | 14½ out |
| » Lost to Senators (57-73), 4-3 | Robert F. Kennedy Stadium (6-2) | 67-60 | |
| » Starters: Mudcat Grant vs Frank Kreutzer | Fourth | 14½ out |
| Wednesday, August 24 |
| » Lost to Senators (58-73), 6-5 | Robert F. Kennedy Stadium (6-3) | 67-61 | Lost 2 |
| » Starters: Jim Perry vs Barry Moore | Fourth | 14½ out |
| Friday, August 26 |
| » Defeated White Sox (66-63), 7-4 | Comiskey Park I (6-0) | 68-61 | |
| » Starters: Jim Merritt vs John Buzhardt | Third | 15 out |
| Saturday, August 27 |
| » Defeated White Sox (66-64), 1-0 | Comiskey Park I (7-0) | 69-61 | Won 2 |
| » Starters: Jim Kaat vs Gary Peters | Third | 14 out |
| Sunday, August 28 |
| » Lost to White Sox (67-64), 4-3 | Comiskey Park I (7-1) | 69-62 | |
| » Starters: Mudcat Grant vs Bruce Howard | Third | 14½ out |
| » Lost to White Sox (68-64), 7-6 | Comiskey Park I (7-2) | 69-63 | Lost 2 |
| » Starters: Dwight Siebler vs Jack Lamabe | Third | 14½ out |
| Monday, August 29 |
| » Defeated Senators (61-74), 6-1 | Metropolitan Stadium (36-28) | 70-63 | |
| » Starters: Frank Kreutzer vs Jim Perry | Third | 13½ out |
| Tuesday, August 30 |
| » Defeated Senators (61-75), 3-1 | Metropolitan Stadium (37-28) | 71-63 | Won 2 |
| » Starters: Jim Hannan vs Jim Merritt | Third | 12½ out |
| Wednesday, August 31 |
| » Defeated Red Sox (60-78), 11-2 | Metropolitan Stadium (38-28) | 72-63 | Won 3 |
| » Starters: Lee Stange vs Jim Kaat | Third | 12½ out |
| Friday, September 2 |
| » Defeated Yankees (61-75), 8-5 | Metropolitan Stadium (39-28) | 73-63 | Won 4 |
| » Starters: Jim Bouton vs Mudcat Grant | Third | 11 out |
| Future Twin Terry Jorgensen is born in Kewaunee, WI. |
| Saturday, September 3 |
| » Defeated Yankees (61-76), 6-1 | Metropolitan Stadium (40-28) | 74-63 | Won 5 |
| » Starters: Fred Talbot vs Jim Perry | Third | 11½ out |
| » Lost to Yankees (62-76), 7-4 | Metropolitan Stadium (40-29) | 74-64 | |
| » Starters: Mel Stottlemyre vs Jim Merritt | Third | 11½ out |
| » Major-league debuts: Jim Ollom (Twins) |
| Sunday, September 4 |
| » Defeated Yankees (62-77), 9-2 | Metropolitan Stadium (41-29) | 75-64 | |
| » Starters: Pedro Ramos vs Jim Kaat | Third | 11½ out |
| Monday, September 5 |
| » Lost to White Sox (73-68), 7-4 | Metropolitan Stadium (41-30) | 75-65 | |
| » Starters: Bruce Howard vs Camilo Pascual | Third | 13 out |
| Tuesday, September 6 |
| » Defeated White Sox (73-69), 4-3 | Metropolitan Stadium (42-30) | 76-65 | |
| » Starters: Tommy John vs Mudcat Grant | Third | 13 out |
| Wednesday, September 7 |
| » Defeated White Sox (73-70), 6-4 | Metropolitan Stadium (43-30) | 77-65 | Won 2 |
| » Starters: Jack Lamabe vs Jim Perry | Third | 13 out |
| Thursday, September 8 |
| Future Twin Mike Dyer is born in Upland, CA. |
| Friday, September 9 |
| » Defeated Orioles (89-52), 6-1 | Metropolitan Stadium (44-30) | 78-65 | Won 3 |
| » Starters: Eddie Watt vs Jim Kaat | Third | 12 out |
| Saturday, September 10 |
| » Defeated Orioles (89-53), 7-2 | Metropolitan Stadium (45-30) | 79-65 | Won 4 |
| » Starters: John Miller vs Jim Merritt | Third | 11 out |
| Future Twin Riccardo Ingram is born in Douglas, GA. |
| Sunday, September 11 |
| » Defeated Orioles (89-54), 11-6 | Metropolitan Stadium (46-30) | 80-65 | Won 5 |
| » Starters: Dave McNally vs Mudcat Grant | Second | 10 out |
| » Major-league debuts: Ron Clark (Twins) |
| Tuesday, September 13 |
| » Lost to Tigers (80-65), 6-5 | Tiger Stadium (3-4) | 80-66 | |
| » Starters: Jim Kaat vs Mickey Lolich | Third | 10 out |
| Wednesday, September 14 |
| » Lost to Tigers (81-65), 3-2 | Tiger Stadium (3-5) | 80-67 | Lost 2 |
| » Starters: Jim Perry vs Denny McLain | Third | 10½ out |
| Thursday, September 15 |
| » Lost to Tigers (82-65), 8-5 | Tiger Stadium (3-6) | 80-68 | Lost 3 |
| » Starters: Mudcat Grant vs Johnny Podres | Third | 12 out |
| » Major-league debuts: George Mitterwald (Twins) |
| Friday, September 16 |
| » Defeated Yankees (66-84), 2-1 | Yankee Stadium (2-5) | 81-68 | |
| » Starters: Jim Merritt vs Jim Bouton | Third | 11 out |
| Saturday, September 17 |
| » Defeated Yankees (66-85), 4-2 | Yankee Stadium (3-5) | 82-68 | Won 2 |
| » Starters: Jim Kaat vs Al Downing | Third | 10 out |
| Sunday, September 18 |
| » Defeated Yankees (66-86), 5-3 | Yankee Stadium (4-5) | 83-68 | Won 3 |
| » Starters: Jim Ollom vs Fritz Peterson | Third | 9 out |
| Tuesday, September 20 |
| » Lost to Indians (76-77), 4-1 | Cleveland Stadium (5-3) | 83-69 | |
| » Starters: Jim Perry vs Luis Tiant | Third | 10½ out |
| Wednesday, September 21 |
| » Lost to Indians (77-77), 6-2 | Cleveland Stadium (5-4) | 83-70 | Lost 2 |
| » Starters: Jim Kaat vs Steve Hargan | Third | 11½ out |
| Friday, September 23 |
| » Defeated Tigers (85-69), 12-4 | Metropolitan Stadium (47-30) | 84-70 | |
| » Starters: Denny McLain vs Mudcat Grant | Third | 11 out |
| » Major-league debuts: Arlo Brunsberg (Tigers) |
| Saturday, September 24 |
| » Lost to Tigers (86-69), 8-1 | Metropolitan Stadium (47-31) | 84-71 | |
| » Starters: Dave Wickersham vs Jim Merritt | Third | 12 out |
| Sunday, September 25 |
| » Defeated Tigers (86-70), 1-0 | Metropolitan Stadium (48-31) | 85-71 | |
| » Starters: Earl Wilson vs Jim Kaat | Third | 11 out |
| Tuesday, September 27 |
| » Defeated Indians (79-79), 5-1 | Metropolitan Stadium (49-31) | 86-71 | Won 2 |
| » Starters: Gary Bell vs Jim Perry | Third | 10½ out |
| Wednesday, September 28 |
| » Lost to Indians (80-79), 4-0 | Metropolitan Stadium (49-32) | 86-72 | |
| » Starters: Luis Tiant vs Jim Kaat | Third | 11 out |
| Friday, September 30 |
| » Defeated Orioles (96-61), 10-7 | Memorial Stadium (1-5) | 87-72 | |
| » Starters: Mudcat Grant vs Dave McNally | Second | 9 out |
| » Defeated Orioles (96-62), 8-2 | Memorial Stadium (2-5) | 88-72 | Won 2 |
| » Starters: Jim Merritt vs Jim Palmer | Second | 9 out |
| Sunday, October 2 |
| » Lost to Orioles |
