| Saturday, January 29 |
| Former Pirate Homer Summa dies in Los Angeles, CA at the age of 68. |
| Wednesday, March 9 |
| Former Pirate Elmer Steele dies in Rhinebeck, NY at the age of 80. |
| Sunday, March 20 |
| Future Pirate Blas Minor is born in Merced, CA. Former Pirate Johnny Morrison dies in Louisville, KY at the age of 71 |
| Tuesday, April 12 |
| » Defeated Braves (0-1), 3-2 | Atlanta-Fulton County Stadium (1-0) | 1-0 | |
| » Starters: Bob Veale vs Tony Cloninger | First | -- |
| Wednesday, April 13 |
| » Defeated Braves (0-2), 6-0 | Atlanta-Fulton County Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Vern Law vs Ken Johnson | First | -- |
| Thursday, April 14 |
| » Major-league debuts: Dooley Womack (Yankees) |
| Friday, April 15 |
| » Lost to Cardinals (1-2), 9-2 | Forbes Field (0-1) | 2-1 | |
| » Starters: Bob Gibson vs Don Cardwell | Third | 1 out |
| » Major-league debuts: Woodie Fryman (Pirates) |
| Saturday, April 16 |
| » Defeated Cardinals (1-3), 5-3 | Forbes Field (1-1) | 3-1 | |
| » Starters: Ray Washburn vs Tommie Sisk | Second | ½ out |
| Sunday, April 17 |
| » Defeated Cardinals (1-4), 6-5 | Forbes Field (2-1) | 4-1 | Won 2 |
| » Starters: Nelson Briles vs Bob Veale | Second | ½ out |
| Monday, April 18 |
| » Defeated Reds (1-3), 4-3 | Forbes Field (3-1) | 5-1 | Won 3 |
| » Starters: Joey Jay vs Luke Walker | First | -- |
| Tuesday, April 19 |
| » Defeated Reds (1-4), 7-3 | Forbes Field (4-1) | 6-1 | Won 4 |
| » Starters: Sammy Ellis vs Steve Blass | First | -- |
| Wednesday, April 20 |
| » Defeated Reds (1-5), 3-2 | Forbes Field (5-1) | 7-1 | Won 5 |
| » Starters: Jim Maloney vs Don Cardwell | First | -- |
| Thursday, April 21 |
| » Defeated Reds (1-6), 2-1 | Forbes Field (6-1) | 8-1 | Won 6 |
| » Starters: Milt Pappas vs Bob Veale | First | -- |
| Friday, April 22 |
| » Lost to Cardinals (4-4), 7-5 | Sportsman's Park III (0-1) | 8-2 | |
| » Starters: Tommie Sisk vs Ray Washburn | First | -- |
| Saturday, April 23 |
| » Defeated Cardinals (4-5), 5-4 | Sportsman's Park III (1-1) | 9-2 | |
| » Starters: Steve Blass vs Nelson Briles | First | -- |
| Sunday, April 24 |
| » Lost to Cardinals (5-5), 5-2 | Sportsman's Park III (1-2) | 9-3 | |
| » Starters: Don Cardwell vs Ray Sadecki | First | -- |
| Monday, April 25 |
| » Lost to Phillies (6-5), 5-0 | Forbes Field (6-2) | 9-4 | Lost 2 |
| » Starters: Jim Bunning vs Bob Veale | First | -- |
| Thursday, April 28 |
| » Defeated Cubs (3-10), 9-6 | Wrigley Field (1-0) | 10-4 | |
| » Starters: Tommie Sisk vs Bill Hands | First | -- |
| Friday, April 29 |
| » Lost to Mets (5-6), 5-2 | Forbes Field (6-3) | 10-5 | |
| » Starters: Rob Gardner vs Steve Blass | First | -- |
| Future Pirate John Vander Wal is born in Grand Rapids, MI. |
| Sunday, May 1 |
| » Defeated Mets (5-7), 8-0 | Forbes Field (7-3) | 11-5 | |
| » Starters: Jack Fisher vs Bob Veale | First | -- |
| Tuesday, May 3 |
| » Defeated Reds (4-12), 5-4 | Crosley Field (1-0) | 12-5 | Won 2 |
| » Starters: Tommie Sisk vs Sammy Ellis | First | -- |
| Wednesday, May 4 |
| » Defeated Reds (4-13), 4-3 | Crosley Field (2-0) | 13-5 | Won 3 |
| » Starters: Steve Blass vs Jim O'Toole | First | -- |
| Former Pirate Bob Elliott dies in San Diego, CA at the age of 50. |
| Thursday, May 5 |
| » Lost to Reds (5-13), 10-6 | Crosley Field (2-1) | 13-6 | |
| » Starters: Bob Veale vs Joey Jay | First | -- |
| Friday, May 6 |
| » Lost to Phillies (10-8), 8-7 | Shibe Park (0-1) | 13-7 | Lost 2 |
| » Starters: Don Schwall vs Bob Buhl | Second | 1½ out |
| Saturday, May 7 |
| » Lost to Phillies (11-8), 7-3 | Shibe Park (0-2) | 13-8 | Lost 3 |
| » Starters: Tommie Sisk vs Jim Bunning | Second | 2½ out |
| Sunday, May 8 |
| » Defeated Phillies (11-9), 3-2 | Shibe Park (1-2) | 14-8 | |
| » Starters: Bob Veale vs John Boozer | Second | 2½ out |
| Tuesday, May 10 |
| » Lost to Giants (19-7), 2-1 | Forbes Field (7-4) | 14-9 | |
| » Starters: Bobby Bolin vs Steve Blass | Second | 3½ out |
| Wednesday, May 11 |
| » Lost to Giants (20-7), 6-1 | Forbes Field (7-5) | 14-10 | Lost 2 |
| » Starters: Gaylord Perry vs Don Schwall | Third | 4½ out |
| Thursday, May 12 |
| » Lost to Giants (21-7), 3-0 | Forbes Field (7-6) | 14-11 | Lost 3 |
| » Starters: Juan Marichal vs Bob Veale | Third | 5½ out |
| Friday, May 13 |
| » Defeated Dodgers (15-14), 4-3 | Forbes Field (8-6) | 15-11 | |
| » Starters: Claude Osteen vs Woodie Fryman | Third | 5½ out |
| Saturday, May 14 |
| » Lost to Dodgers (16-14), 4-1 | Forbes Field (8-7) | 15-12 | |
| » Starters: Sandy Koufax vs Steve Blass | Third | 5½ out |
| Sunday, May 15 |
| » Lost to Dodgers (17-14), 3-1 | Forbes Field (8-8) | 15-13 | Lost 2 |
| » Starters: Don Sutton vs Don Cardwell | Fourth | 5½ out |
| Tuesday, May 17 |
| » Defeated Braves (15-19), 5-2 | Forbes Field (9-8) | 16-13 | |
| » Starters: Wade Blasingame vs Bob Veale | Fourth | 4½ out |
| Wednesday, May 18 |
| » Lost to Braves (16-19), 4-2 | Forbes Field (9-9) | 16-14 | |
| » Starters: Ken Johnson vs Vern Law | Fifth | 5½ out |
| Friday, May 20 |
| » Defeated Dodgers (19-16), 7-3 | Dodger Stadium (1-0) | 17-14 | |
| » Starters: Woodie Fryman vs Don Sutton | Third | 4 out |
| Saturday, May 21 |
| » Lost to Dodgers (20-16), 5-4 | Dodger Stadium (1-1) | 17-15 | |
| » Starters: Steve Blass vs Don Drysdale | Fourth | 5 out |
| Sunday, May 22 |
| » Defeated Dodgers (20-17), 4-0 | Dodger Stadium (2-1) | 18-15 | |
| » Starters: Bob Veale vs Claude Osteen | Third | 4½ out |
| Monday, May 23 |
| » Lost to Dodgers (21-17), 3-2 | Dodger Stadium (2-2) | 18-16 | |
| » Starters: Don Cardwell vs Sandy Koufax | Fifth | 5 out |
| Tuesday, May 24 |
| » Lost to Giants (26-13), 5-2 | Candlestick Park (0-1) | 18-17 | Lost 2 |
| » Starters: Vern Law vs Gaylord Perry | Fifth | 6 out |
| Wednesday, May 25 |
| » Defeated Giants (26-14), 3-2 | Candlestick Park (1-1) | 19-17 | |
| » Starters: Don Schwall vs Bob Shaw | Fourth | 5 out |
| Thursday, May 26 |
| » Defeated Astros (23-17), 3-2 | Astrodome (1-0) | 20-17 | Won 2 |
| » Starters: Steve Blass vs Turk Farrell | Third | 5 out |
| Friday, May 27 |
| » Defeated Astros (23-18), 6-0 | Astrodome (2-0) | 21-17 | Won 3 |
| » Starters: Bob Veale vs Barry Latman | Fourth | 4 out |
| Saturday, May 28 |
| » Lost to Astros (24-18), 2-1 | Astrodome (2-1) | 21-18 | |
| » Starters: Don Cardwell vs Dave Giusti | Fourth | 3½ out |
| » Defeated Astros (24-19), 5-2 | Astrodome (3-1) | 22-18 | |
| » Starters: Woodie Fryman vs Robin Roberts | Fourth | 3½ out |
| Sunday, May 29 |
| » Lost to Astros (25-19), 3-2 | Astrodome (3-2) | 22-19 | |
| » Starters: Vern Law vs Larry Dierker | Fourth | 4½ out |
| Monday, May 30 |
| » Defeated Cubs (12-28), 3-2 | Forbes Field (10-9) | 23-19 | |
| » Starters: Dick Ellsworth vs Don Schwall | Third | 4 out |
| » Defeated Cubs (12-29), 5-3 | Forbes Field (11-9) | 24-19 | Won 2 |
| » Starters: Ken Holtzman vs Steve Blass | Third | 4 out |
| Tuesday, May 31 |
| » Lost to Cubs (13-29), 2-1 | Forbes Field (11-10) | 24-20 | |
| » Starters: Ernie Broglio vs Bob Veale | Third | 5 out |
| Wednesday, June 1 |
| » Defeated Mets (15-23), 3-1 | Shea Stadium (1-0) | 25-20 | |
| » Starters: Don Cardwell vs Dennis Ribant | Third | 5 out |
| Thursday, June 2 |
| » Defeated Mets (15-24), 5-0 | Shea Stadium (2-0) | 26-20 | Won 2 |
| » Starters: Vern Law vs Rob Gardner | Third | 5 out |
| Friday, June 3 |
| » Defeated Astros (27-22), 7-2 | Forbes Field (12-10) | 27-20 | Won 3 |
| » Starters: Larry Dierker vs Woodie Fryman | Third | 4 out |
| Saturday, June 4 |
| » Defeated Astros (27-23), 9-6 | Forbes Field (13-10) | 28-20 | Won 4 |
| » Starters: Robin Roberts vs Steve Blass | Third | 3 out |
| Sunday, June 5 |
| » Defeated Astros (27-24), 10-5 | Forbes Field (14-10) | 29-20 | Won 5 |
| » Starters: Turk Farrell vs Bob Veale | Third | 3 out |
| Tuesday, June 7 |
| » Defeated Cardinals (21-27), 9-1 | Forbes Field (15-10) | 30-20 | Won 6 |
| » Starters: Bob Gibson vs Don Cardwell | Third | 1½ out |
| Wednesday, June 8 |
| » Lost to Cardinals (22-27), 11-5 | Forbes Field (15-11) | 30-21 | |
| » Starters: Nelson Briles vs Vern Law | Third | 1½ out |
| Thursday, June 9 |
| » Lost to Cardinals (23-27), 4-2 | Forbes Field (15-12) | 30-22 | Lost 2 |
| » Starters: Al Jackson vs Woodie Fryman | Third | 2½ out |
| Friday, June 10 |
| » Lost to Braves (27-30), 8-2 | Forbes Field (15-13) | 30-23 | Lost 3 |
| » Starters: Ken Johnson vs Bob Veale | Third | 2½ out |
| Saturday, June 11 |
| » Defeated Braves (27-31), 5-3 | Forbes Field (16-13) | 31-23 | |
| » Starters: Arnold Umbach vs Steve Blass | Third | 2½ out |
| Sunday, June 12 |
| » Defeated Braves (27-32), 11-8 | Forbes Field (17-13) | 32-23 | Won 2 |
| » Starters: Denny Lemaster vs Don Cardwell | Third | 1½ out |
| Monday, June 13 |
| » Defeated Reds (23-31), 5-4 | Forbes Field (18-13) | 33-23 | Won 3 |
| » Starters: Joey Jay vs Vern Law | Third | 1½ out |
| Tuesday, June 14 |
| » Lost to Reds (24-31), 3-0 | Forbes Field (18-14) | 33-24 | |
| » Starters: Jim Maloney vs Woodie Fryman | Third | 2½ out |
| Future Pirate Randy Tomlin is born in Bainbridge, MD. |
| Wednesday, June 15 |
| » Lost to Cardinals (28-29), 1-0 | Busch Stadium II (0-1) | 33-25 | Lost 2 |
| » Starters: Bob Veale vs Bob Gibson | Third | 3½ out |
| Thursday, June 16 |
| » Defeated Cardinals (28-30), 2-1 | Busch Stadium II (1-1) | 34-25 | |
| » Starters: Steve Blass vs Nelson Briles | Third | 3½ out |
| Friday, June 17 |
| » Defeated Braves (29-36), 4-2 | Atlanta-Fulton County Stadium (3-0) | 35-25 | Won 2 |
| » Starters: Don Cardwell vs Clay Carroll | Second | 3½ out |
| Saturday, June 18 |
| » Defeated Braves (29-37), 9-6 | Atlanta-Fulton County Stadium (4-0) | 36-25 | Won 3 |
| » Starters: Vern Law vs Wade Blasingame | Second | 2½ out |
| Sunday, June 19 |
| » Defeated Braves (29-38), 2-1 | Atlanta-Fulton County Stadium (5-0) | 37-25 | Won 4 |
| » Starters: Bob Veale vs Ken Johnson | Second | 1½ out |
| Tuesday, June 21 |
| » Lost to Reds (30-34), 11-8 | Crosley Field (2-2) | 37-26 | |
| » Starters: Woodie Fryman vs Hank Fischer | Second | 2½ out |
| Wednesday, June 22 |
| » Lost to Reds (31-34), 4-3 | Crosley Field (2-3) | 37-27 | Lost 2 |
| » Starters: Steve Blass vs Jim Maloney | Second | 4 out |
| Thursday, June 23 |
| » Lost to Reds (32-34), 5-3 | Crosley Field (2-4) | 37-28 | Lost 3 |
| » Starters: Don Cardwell vs Milt Pappas | Third | 5 out |
| Friday, June 24 |
| » Defeated Phillies (36-33), 3-1 | Shibe Park (2-2) | 38-28 | |
| » Starters: Bob Veale vs Jim Bunning | Third | 4 out |
| Saturday, June 25 |
| » Lost to Phillies (37-33), 8-7 | Shibe Park (2-3) | 38-29 | |
| » Starters: Vern Law vs Chris Short | Second | 4 out |
| Sunday, June 26 |
| » Defeated Phillies (37-34), 2-0 | Shibe Park (3-3) | 39-29 | |
| » Starters: Woodie Fryman vs Larry Jackson | Second | 4 out |
| Former Pirate Lil Stoner dies in Enid, OK at the age of 68. |
| Monday, June 27 |
| » Defeated Astros (39-33), 8-5 | Forbes Field (19-14) | 40-29 | Won 2 |
| » Starters: Bob Bruce vs Steve Blass | Second | 4 out |
| Tuesday, June 28 |
| » Defeated Astros (39-34), 4-3 | Forbes Field (20-14) | 41-29 | Won 3 |
| » Starters: Dave Giusti vs Bob Veale | Second | 4 out |
| Wednesday, June 29 |
| » Defeated Astros (39-35), 6-5 | Forbes Field (21-14) | 42-29 | Won 4 |
| » Starters: Larry Dierker vs Don Cardwell | Second | 3 out |
| Thursday, June 30 |
| » Defeated Astros (39-36), 9-0 | Forbes Field (22-14) | 43-29 | Won 5 |
| » Starters: Robin Roberts vs Vern Law | Second | 3 out |
| Friday, July 1 |
| » Defeated Mets (29-42), 12-0 | Shea Stadium (3-0) | 44-29 | Won 6 |
| » Starters: Woodie Fryman vs Jack Fisher | Second | 3 out |
| Saturday, July 2 |
| » Lost to Mets (30-42), 4-3 | Shea Stadium (3-1) | 44-30 | |
| » Starters: Steve Blass vs Dennis Ribant | Second | 3 out |
| Sunday, July 3 |
| » Defeated Mets (30-43), 8-7 | Shea Stadium (4-1) | 45-30 | |
| » Starters: Bob Veale vs Dick Rusteck | Second | 2½ out |
| » Lost to Mets (31-43), 9-8 | Shea Stadium (4-2) | 45-31 | |
| » Starters: Don Cardwell vs Bob Friend | Second | 2½ out |
| Monday, July 4 |
| » Defeated Cubs (23-53), 7-5 | Wrigley Field (2-0) | 46-31 | |
| » Starters: Vern Law vs Bill Hands | Second | 2½ out |
| » Lost to Cubs (24-53), 6-4 | Wrigley Field (2-1) | 46-32 | |
| » Starters: Tommie Sisk vs Ken Holtzman | Second | 2½ out |
| Tuesday, July 5 |
| » Defeated Cubs (24-54), 6-0 | Wrigley Field (3-1) | 47-32 | |
| » Starters: Woodie Fryman vs Bill Faul | Second | 1½ out |
| Wednesday, July 6 |
| » Defeated Cubs (24-55), 10-5 | Wrigley Field (4-1) | 48-32 | Won 2 |
| » Starters: Steve Blass vs Dick Ellsworth | Second | 1½ out |
| Thursday, July 7 |
| » Lost to Cubs (25-55), 5-4 | Wrigley Field (4-2) | 48-33 | |
| » Starters: Bob Veale vs Curt Simmons | Second | 2½ out |
| Friday, July 8 |
| » Defeated Mets (35-45), 10-2 | Forbes Field (23-14) | 49-33 | |
| » Starters: Bob Shaw vs Vern Law | Second | 2 out |
| » Defeated Mets (35-46), 9-2 | Forbes Field (24-14) | 50-33 | Won 2 |
| » Starters: Jack Fisher vs Tommie Sisk | Second | 2 out |
| Saturday, July 9 |
| » Defeated Mets (35-47), 6-3 | Forbes Field (25-14) | 51-33 | Won 3 |
| » Starters: Bill Hepler vs Woodie Fryman | Second | 2 out |
| Sunday, July 10 |
| » Defeated Mets (35-48), 9-4 | Forbes Field (26-14) | 52-33 | Won 4 |
| » Starters: Rob Gardner vs Steve Blass | Second | 1 out |
| Thursday, July 14 |
| » Defeated Cubs (26-58), 10-4 | Forbes Field (27-14) | 53-33 | Won 5 |
| » Starters: Dick Ellsworth vs Bob Veale | First | -- |
| Friday, July 15 |
| » Lost to Cubs (27-58), 5-4 | Forbes Field (27-15) | 53-34 | |
| » Starters: Robin Roberts vs Vern Law | Second | 1 out |
| » Major-league debuts: Gene Michael (Pirates) |
| Saturday, July 16 |
| » Lost to Cubs (28-58), 4-1 | Forbes Field (27-16) | 53-35 | Lost 2 |
| » Starters: Bill Hands vs Woodie Fryman | Second | 1 out |
| Sunday, July 17 |
| » Defeated Giants (55-36), 7-4 | Forbes Field (28-16) | 54-35 | |
| » Starters: Ron Herbel vs Steve Blass | First | -- |
| » Defeated Giants (55-37), 7-1 | Forbes Field (29-16) | 55-35 | Won 2 |
| » Starters: Bob Priddy vs Tommie Sisk | First | -- |
| Monday, July 18 |
| » Lost to Giants (56-37), 3-2 | Forbes Field (29-17) | 55-36 | |
| » Starters: Gaylord Perry vs Bob Veale | First | -- |
| Wednesday, July 20 |
| » Defeated Dodgers (51-39), 8-5 | Dodger Stadium (3-2) | 56-36 | |
| » Starters: Vern Law vs Don Drysdale | First | -- |
| Thursday, July 21 |
| » Lost to Dodgers (52-39), 4-3 | Dodger Stadium (3-3) | 56-37 | |
| » Starters: Woodie Fryman vs Don Sutton | First | -- |
| Friday, July 22 |
| » Lost to Astros (48-46), 5-2 | Astrodome (3-3) | 56-38 | Lost 2 |
| » Starters: Steve Blass vs Larry Dierker | First | -- |
| Saturday, July 23 |
| » Defeated Astros (48-47), 4-3 | Astrodome (4-3) | 57-38 | |
| » Starters: Vern Law vs Bob Bruce | First | -- |
| Sunday, July 24 |
| » Defeated Astros (48-48), 11-6 | Astrodome (5-3) | 58-38 | Won 2 |
| » Starters: Tommie Sisk vs Mike Cuellar | First | -- |
| Monday, July 25 |
| » Lost to Giants (59-40), 2-1 | Candlestick Park (1-2) | 58-39 | |
| » Starters: Woodie Fryman vs Juan Marichal | First | -- |
| Tuesday, July 26 |
| » Lost to Giants (60-40), 8-3 | Candlestick Park (1-3) | 58-40 | Lost 2 |
| » Starters: Steve Blass vs Gaylord Perry | Second | 1 out |
| Wednesday, July 27 |
| » Defeated Giants (60-41), 5-3 | Candlestick Park (2-3) | 59-40 | |
| » Starters: Tommie Sisk vs Bobby Bolin | First | -- |
| Friday, July 29 |
| » Defeated Phillies (52-49), 5-3 | Forbes Field (30-17) | 60-40 | Won 2 |
| » Starters: Chris Short vs Don Cardwell | First | -- |
| Saturday, July 30 |
| » Lost to Phillies (53-49), 4-1 | Forbes Field (30-18) | 60-41 | |
| » Starters: Larry Jackson vs Woodie Fryman | First | -- |
| Sunday, July 31 |
| » Lost to Phillies (54-49), 8-1 | Forbes Field (30-19) | 60-42 | Lost 2 |
| » Starters: Jim Bunning vs Vern Law | Second | 1 out |
| » Lost to Phillies (55-49), 6-5 | Forbes Field (30-20) | 60-43 | Lost 3 |
| » Starters: Bob Buhl vs Steve Blass | Second | 1 out |
| Monday, August 1 |
| » Lost to Dodgers (60-42), 5-1 | Forbes Field (30-21) | 60-44 | Lost 4 |
| » Starters: Sandy Koufax vs Tommie Sisk | Third | 1 out |
| Tuesday, August 2 |
| » Defeated Dodgers (60-43), 6-5 | Forbes Field (31-21) | 61-44 | |
| » Starters: Don Drysdale vs Woodie Fryman | Third | 1 out |
| Future Pirate Tim Wakefield is born in Melbourne, FL. |
| Wednesday, August 3 |
| » Defeated Dodgers (60-44), 3-1 | Forbes Field (32-21) | 62-44 | Won 2 |
| » Starters: Don Sutton vs Bob Veale | Second | 1 out |
| Thursday, August 4 |
| » Defeated Dodgers (60-45), 8-1 | Forbes Field (33-21) | 63-44 | Won 3 |
| » Starters: Claude Osteen vs Vern Law | First | -- |
| Friday, August 5 |
| » Lost to Reds (55-53), 4-3 | Forbes Field (33-22) | 63-45 | |
| » Starters: Milt Pappas vs Steve Blass | First | -- |
| Saturday, August 6 |
| » Defeated Reds (55-54), 9-3 | Forbes Field (34-22) | 64-45 | |
| » Starters: Jim O'Toole vs Tommie Sisk | First | -- |
| Future Pirate Stan Belinda is born in Huntingdon, PA. |
| Sunday, August 7 |
| » Lost to Reds (56-54), 9-7 | Forbes Field (34-23) | 64-46 | |
| » Starters: Joe Nuxhall vs Bob Veale | Second | 1 out |
| Tuesday, August 9 |
| » Defeated Mets (49-62), 2-1 | Forbes Field (35-23) | 65-46 | |
| » Starters: Dennis Ribant vs Woodie Fryman | First | -- |
| Wednesday, August 10 |
| » Defeated Mets (49-63), 10-4 | Forbes Field (36-23) | 66-46 | Won 2 |
| » Starters: Bob Shaw vs Vern Law | First | -- |
| Thursday, August 11 |
| » Defeated Mets (49-64), 7-5 | Forbes Field (37-23) | 67-46 | Won 3 |
| » Starters: Ralph Terry vs Tommie Sisk | First | -- |
| Friday, August 12 |
| » Defeated Reds (58-56), 14-11 | Crosley Field (3-4) | 68-46 | Won 4 |
| » Starters: Bob Veale vs Sammy Ellis | First | -- |
| Saturday, August 13 |
| » Lost to Reds (59-56), 11-0 | Crosley Field (3-5) | 68-47 | |
| » Starters: Woodie Fryman vs Jim Maloney | First | -- |
| Sunday, August 14 |
| » Defeated Reds (59-57), 4-2 | Crosley Field (4-5) | 69-47 | |
| » Starters: Vern Law vs Milt Pappas | First | -- |
| Tuesday, August 16 |
| » Defeated Mets (51-67), 3-0 | Shea Stadium (5-2) | 70-47 | Won 2 |
| » Starters: Tommie Sisk vs Tug McGraw | First | -- |
| Wednesday, August 17 |
| » Lost to Mets (52-67), 8-7 | Shea Stadium (5-3) | 70-48 | |
| » Starters: Bob Veale vs Jack Fisher | First | -- |
| Thursday, August 18 |
| » Lost to Mets (53-67), 9-5 | Shea Stadium (5-4) | 70-49 | Lost 2 |
| » Starters: Woodie Fryman vs Rob Gardner | First | -- |
| Friday, August 19 |
| » Lost to Cubs (41-79), 4-3 | Wrigley Field (4-3) | 70-50 | Lost 3 |
| » Starters: Vern Law vs Dick Ellsworth | First | -- |
| Saturday, August 20 |
| » Defeated Cubs (41-80), 3-2 | Wrigley Field (5-3) | 71-50 | |
| » Starters: Tommie Sisk vs Bill Hands | First | -- |
| Sunday, August 21 |
| » Defeated Cubs (41-81), 8-1 | Wrigley Field (6-3) | 72-50 | Won 2 |
| » Starters: Bob Veale vs Robin Roberts | First | -- |
| Monday, August 22 |
| » Defeated Phillies (67-58), 6-5 | Forbes Field (38-23) | 73-50 | Won 3 |
| » Starters: Bob Buhl vs Woodie Fryman | First | -- |
| Tuesday, August 23 |
| » Lost to Phillies (68-58), 5-4 | Forbes Field (38-24) | 73-51 | |
| » Starters: Chris Short vs Vern Law | Second | 1 out |
| Wednesday, August 24 |
| » Defeated Phillies (68-59), 6-4 | Forbes Field (39-24) | 74-51 | |
| » Starters: Larry Jackson vs Tommie Sisk | First | -- |
| Thursday, August 25 |
| » Lost to Phillies (69-59), 4-1 | Forbes Field (39-25) | 74-52 | |
| » Starters: Jim Bunning vs Bob Veale | Second | ½ out |
| Friday, August 26 |
| » Defeated Cardinals (65-62), 7-4 | Busch Stadium II (2-1) | 75-52 | |
| » Starters: Woodie Fryman vs Al Jackson | First | -- |
| Saturday, August 27 |
| » Lost to Cardinals (66-62), 5-1 | Busch Stadium II (2-2) | 75-53 | |
| » Starters: Steve Blass vs Bob Gibson | Second | ½ out |
| Sunday, August 28 |
| » Lost to Cardinals (67-62), 3-2 | Busch Stadium II (2-3) | 75-54 | Lost 2 |
| » Starters: Vern Law vs Ray Washburn | First | -- |
| » Defeated Cardinals (67-63), 5-1 | Busch Stadium II (3-3) | 76-54 | |
| » Starters: Billy O'Dell vs Steve Carlton | First | -- |
| Monday, August 29 |
| » Lost to Astros (61-70), 2-0 | Forbes Field (39-26) | 76-55 | |
| » Starters: Mike Cuellar vs Bob Veale | First | -- |
| Former Pirate Bobby Schang dies in Sacramento, CA at the age of 80. |
| Tuesday, August 30 |
| » Defeated Astros (61-71), 8-2 | Forbes Field (40-26) | 77-55 | |
| » Starters: Dave Giusti vs Woodie Fryman | First | -- |
| Wednesday, August 31 |
| » Defeated Dodgers (74-57), 4-3 | Forbes Field (41-26) | 78-55 | Won 2 |
| » Starters: Don Drysdale vs Steve Blass | First | -- |
| Thursday, September 1 |
| » Lost to Dodgers (75-57), 4-3 | Forbes Field (41-27) | 78-56 | |
| » Starters: Don Sutton vs Vern Law | First | -- |
| Friday, September 2 |
| » Defeated Cubs (47-87), 7-3 | Forbes Field (42-27) | 79-56 | |
| » Starters: Fergie Jenkins vs Bob Veale | First | -- |
| Saturday, September 3 |
| » Defeated Cubs (47-88), 9-1 | Forbes Field (43-27) | 80-56 | Won 2 |
| » Starters: Ken Holtzman vs Tommie Sisk | First | -- |
| Sunday, September 4 |
| » Defeated Cubs (47-89), 8-5 | Forbes Field (44-27) | 81-56 | Won 3 |
| » Starters: Bill Hands vs Woodie Fryman | First | -- |
| Monday, September 5 |
| » Defeated Braves (68-70), 13-5 | Forbes Field (45-27) | 82-56 | Won 4 |
| » Starters: Dick Kelley vs Vern Law | First | -- |
| » Lost to Braves (69-70), 7-5 | Forbes Field (45-28) | 82-57 | |
| » Starters: Tony Cloninger vs Steve Blass | First | -- |
| Tuesday, September 6 |
| » Lost to Braves (70-70), 4-1 | Forbes Field (45-29) | 82-58 | Lost 2 |
| » Starters: Pat Jarvis vs Bob Veale | First | -- |
| Wednesday, September 7 |
| » Lost to Braves (71-70), 8-3 | Forbes Field (45-30) | 82-59 | Lost 3 |
| » Starters: Ken Johnson vs Tommie Sisk | First | -- |
| Thursday, September 8 |
| Future Pirate Mike Dyer is born in Upland, CA. |
| Friday, September 9 |
| » Defeated Cardinals (72-70), 3-2 | Forbes Field (46-30) | 83-59 | |
| » Starters: Ray Washburn vs Woodie Fryman | First | -- |
| Saturday, September 10 |
| » Lost to Cardinals (73-70), 6-5 | Forbes Field (46-31) | 83-60 | |
| » Starters: Bob Gibson vs Vern Law | First | -- |
| Sunday, September 11 |
| » Lost to Cardinals (74-70), 4-3 | Forbes Field (46-32) | 83-61 | Lost 2 |
| » Starters: Al Jackson vs Bob Veale | Second | 1 out |
| » Major-league debuts: Dick Hughes (Cardinals) |
| Tuesday, September 13 |
| » Defeated Astros (63-85), 9-3 | Astrodome (6-3) | 84-61 | |
| » Starters: Tommie Sisk vs Dave Giusti | Second | 1½ out |
| Former Pirate Ralph Comstock dies in Toledo, OH at the age of 76. |
| Thursday, September 15 |
| » Lost to Dodgers (86-59), 5-3 | Dodger Stadium (3-4) | 84-62 | |
| » Starters: Vern Law vs Don Drysdale | Second | 2½ out |
| » Major-league debuts: Jim Shellenback (Pirates) |
| Friday, September 16 |
| » Lost to Dodgers (87-59), 5-1 | Dodger Stadium (3-5) | 84-63 | Lost 2 |
| » Starters: Bob Veale vs Sandy Koufax | Second | 3½ out |
| » Major-league debuts: Tom Hutton (Dodgers) |
| Saturday, September 17 |
| » Defeated Dodgers (87-60), 9-5 | Dodger Stadium (4-5) | 85-63 | |
| » Starters: Tommie Sisk vs Joe Moeller | Second | 2½ out |
| Sunday, September 18 |
| » Defeated Giants (85-65), 3-1 | Candlestick Park (3-3) | 86-63 | Won 2 |
| » Starters: Woodie Fryman vs Gaylord Perry | Second | 1½ out |
| Monday, September 19 |
| » Defeated Giants (85-66), 6-1 | Candlestick Park (4-3) | 87-63 | Won 3 |
| » Starters: Vern Law vs Bobby Bolin | Second | 1½ out |
| » Major-league debuts: Don Bosch (Pirates) |
| Tuesday, September 20 |
| » Defeated Giants (85-67), 6-0 | Candlestick Park (5-3) | 88-63 | Won 4 |
| » Starters: Bob Veale vs Ron Herbel | Second | 1½ out |
| Wednesday, September 21 |
| » Lost to Giants (86-67), 6-5 | Candlestick Park (5-4) | 88-64 | |
| » Starters: Tommie Sisk vs Juan Marichal | Second | 1½ out |
| Thursday, September 22 |
| » Lost to Braves (82-71), 14-1 | Atlanta-Fulton County Stadium (5-1) | 88-65 | Lost 2 |
| » Starters: Woodie Fryman vs Pat Jarvis | Second | 2 out |
| Friday, September 23 |
| » Defeated Braves (82-72), 3-0 | Atlanta-Fulton County Stadium (6-1) | 89-65 | |
| » Starters: Bob Veale vs Don Schwall | Second | 2½ out |
| Saturday, September 24 |
| » Defeated Braves (82-73), 8-6 | Atlanta-Fulton County Stadium (7-1) | 90-65 | Won 2 |
| » Starters: Vern Law vs Tony Cloninger | Second | 1½ out |
| Sunday, September 25 |
| » Lost to Braves (83-73), 6-2 | Atlanta-Fulton County Stadium (7-2) | 90-66 | |
| » Starters: Tommie Sisk vs Dick Kelley | Second | 1½ out |
| Monday, September 26 |
| » Lost to Phillies (85-72), 5-4 | Shibe Park (3-4) | 90-67 | Lost 2 |
| » Starters: Woodie Fryman vs Rick Wise | Second | 2½ out |
| Wednesday, |
