| Monday, January 4 |
| Future Tiger Kevin Wickander is born in Fort Dodge, IA. |
| Monday, January 11 |
| Former Tiger Wally Pipp dies in Grand Rapids, MI at the age of 72. |
| Sunday, January 24 |
| Former Tiger Ralph Young dies in Philadelphia, PA at the age of 76. |
| Thursday, January 28 |
| Former Tiger Billy Sullivan dies in Newberg, OR at the age of 90. |
| Monday, February 22 |
| Former Tiger Clarence Huber dies in Laredo, TX at the age of 69. |
| Wednesday, March 3 |
| Future Tiger A.J. Sager is born in Columbus, OH. |
| Saturday, March 6 |
| Former Tiger Wally Schang dies in St.Louis, MO at the age of 76. |
| Thursday, March 18 |
| Future Tiger Geronimo Berroa is born in Santo Domingo, D.R. |
| Friday, April 9 |
| Future Tiger Hal Morris is born in Fort Rucker, AL. |
| Monday, April 12 |
| » Defeated Athletics (0-1), 6-2 | Municipal Stadium (1-0) | 1-0 | |
| » Starters: Mickey Lolich vs Moe Drabowsky | First | -- |
| Tuesday, April 13 |
| » Defeated Athletics (0-2), 11-4 | Municipal Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Hank Aguirre vs Diego Segui | First | -- |
| Thursday, April 15 |
| » Defeated Twins (1-1), 6-4 | Metropolitan Stadium (1-0) | 3-0 | Won 3 |
| » Starters: Dave Wickersham vs Camilo Pascual | First | -- |
| Saturday, April 17 |
| » Lost to Angels (2-2), 3-1 | Dodger Stadium (0-1) | 3-1 | |
| » Starters: Phil Regan vs Fred Newman | First | -- |
| Sunday, April 18 |
| » Defeated Angels (2-3), 4-1 | Dodger Stadium (1-1) | 4-1 | |
| » Starters: Denny McLain vs Rudy May | First | -- |
| » Major-league debuts: Rudy May (Angels) Jackie Moore and Ray Oyler (Tigers) |
| Monday, April 19 |
| » Lost to Angels (3-3), 4-2 | Dodger Stadium (1-2) | 4-2 | |
| » Starters: Mickey Lolich vs Marcelino Lopez | Second | 1 out |
| Tuesday, April 20 |
| » Major-league debuts: Bob Schroder (Giants) |
| Wednesday, April 21 |
| » Defeated Athletics (2-5), 1-0 | Tiger Stadium (1-0) | 5-2 | |
| » Starters: John O'Donoghue vs Hank Aguirre | Second | 1 out |
| Friday, April 23 |
| » Lost to Twins (6-1), 8-6 | Tiger Stadium (1-1) | 5-3 | |
| » Starters: Mudcat Grant vs Dave Wickersham | Third | 1½ out |
| Saturday, April 24 |
| » Defeated Twins (6-2), 7-4 | Tiger Stadium (2-1) | 6-3 | |
| » Starters: Dick Stigman vs Phil Regan | Third | ½ out |
| » Major-league debuts: John Sevcik (Twins) |
| Tuesday, April 27 |
| » Lost to Angels (5-6), 4-3 | Tiger Stadium (2-2) | 6-4 | |
| » Starters: Fred Newman vs Denny McLain | Third | 1½ out |
| Future Tiger Bob MacDonald is born in East Orange, NJ. |
| Wednesday, April 28 |
| » Defeated Angels (5-7), 5-4 | Tiger Stadium (3-2) | 7-4 | |
| » Starters: Dean Chance vs Mickey Lolich | Third | 1 out |
| Friday, April 30 |
| » Defeated Red Sox (5-5), 4-1 | Tiger Stadium (4-2) | 8-4 | Won 2 |
| » Starters: Dave Morehead vs Hank Aguirre | Second | ½ out |
| Saturday, May 1 |
| » Defeated Red Sox (5-6), 9-8 | Tiger Stadium (5-2) | 9-4 | Won 3 |
| » Starters: Jim Lonborg vs Dave Wickersham | First | -- |
| Sunday, May 2 |
| » Lost to Red Sox (6-6), 2-1 | Tiger Stadium (5-3) | 9-5 | |
| » Starters: Earl Wilson vs Phil Regan | Third | 1 out |
| » Lost to Red Sox (7-6), 10-3 | Tiger Stadium (5-4) | 9-6 | Lost 2 |
| » Starters: Bill Monbouquette vs Joe Sparma | Third | 1 out |
| Tuesday, May 4 |
| » Lost to White Sox (11-5), 10-6 | Tiger Stadium (5-5) | 9-7 | Lost 3 |
| » Starters: Gary Peters vs Denny McLain | Third | 2 out |
| Wednesday, May 5 |
| » Lost to White Sox (12-5), 4-0 | Tiger Stadium (5-6) | 9-8 | Lost 4 |
| » Starters: John Buzhardt vs Mickey Lolich | Fifth | 4 out |
| » Lost to White Sox (13-5), 4-1 | Tiger Stadium (5-7) | 9-9 | Lost 5 |
| » Starters: Joe Horlen vs Dave Wickersham | Fifth | 4 out |
| Friday, May 7 |
| » Major-league debuts: Tom Harrison (Athletics) |
| Saturday, May 8 |
| » Defeated Orioles (10-10), 4-3 | Memorial Stadium (1-0) | 10-9 | |
| » Starters: Hank Aguirre vs Dave McNally | Fifth | 3½ out |
| Sunday, May 9 |
| » Lost to Orioles (11-10), 7-1 | Memorial Stadium (1-1) | 10-10 | |
| » Starters: Phil Regan vs Milt Pappas | Sixth | 4 out |
| » Lost to Orioles (12-10), 5-4 | Memorial Stadium (1-2) | 10-11 | Lost 2 |
| » Starters: Denny McLain vs Jim Palmer | Sixth | 4 out |
| Monday, May 10 |
| » Defeated Orioles (12-11), 5-4 | Memorial Stadium (2-2) | 11-11 | |
| » Starters: Mickey Lolich vs Robin Roberts | Sixth | 3½ out |
| Tuesday, May 11 |
| » Defeated Senators (10-15), 7-6 | Robert F. Kennedy Stadium (1-0) | 12-11 | Won 2 |
| » Starters: Dave Wickersham vs Frank Kreutzer | Sixth | 3½ out |
| Wednesday, May 12 |
| » Defeated Senators (10-16), 5-2 | Robert F. Kennedy Stadium (2-0) | 13-11 | Won 3 |
| » Starters: Joe Sparma vs Mike McCormick | Fifth | 3½ out |
| Thursday, May 13 |
| » Defeated Senators (10-17), 13-3 | Robert F. Kennedy Stadium (3-0) | 14-11 | Won 4 |
| » Starters: Hank Aguirre vs Bennie Daniels | Fifth | 3 out |
| Friday, May 14 |
| » Defeated Red Sox (11-14), 12-8 | Fenway Park (1-0) | 15-11 | Won 5 |
| » Starters: Denny McLain vs Dennis Bennett | Third | 3 out |
| Saturday, May 15 |
| » Defeated Red Sox (11-15), 6-2 | Fenway Park (2-0) | 16-11 | Won 6 |
| » Starters: Mickey Lolich vs Jim Lonborg | Third | 3 out |
| Sunday, May 16 |
| » Lost to Red Sox (12-15), 5-0 | Fenway Park (2-1) | 16-12 | |
| » Starters: Dave Wickersham vs Earl Wilson | Third | 5 out |
| » Lost to Red Sox (13-15), 4-3 | Fenway Park (2-2) | 16-13 | Lost 2 |
| » Starters: Joe Sparma vs Bill Monbouquette | Third | 5 out |
| Tuesday, May 18 |
| » Lost to Senators (13-19), 15-9 | Tiger Stadium (5-8) | 16-14 | Lost 3 |
| » Starters: Phil Ortega vs Hank Aguirre | Fifth | 6½ out |
| Wednesday, May 19 |
| » Defeated Senators (13-20), 4-0 | Tiger Stadium (6-8) | 17-14 | |
| » Starters: Bennie Daniels vs Denny McLain | Third | 5½ out |
| Former Tiger Eric Erickson dies in Jamestown, NY at the age of 71. |
| Thursday, May 20 |
| » Defeated Senators (13-21), 9-8 | Tiger Stadium (7-8) | 18-14 | Won 2 |
| » Starters: Frank Kreutzer vs Mickey Lolich | Third | 5 out |
| Friday, May 21 |
| » Lost to Orioles (18-16), 5-2 | Tiger Stadium (7-9) | 18-15 | |
| » Starters: Milt Pappas vs Dave Wickersham | Fourth | 5 out |
| Saturday, May 22 |
| » Defeated Orioles (18-17), 8-4 | Tiger Stadium (8-9) | 19-15 | |
| » Starters: Robin Roberts vs Joe Sparma | Third | 4 out |
| Sunday, May 23 |
| » Lost to Orioles (19-17), 7-3 | Tiger Stadium (8-10) | 19-16 | |
| » Starters: Steve Barber vs Hank Aguirre | Fourth | 5½ out |
| » Lost to Orioles (20-17), 8-3 | Tiger Stadium (8-11) | 19-17 | Lost 2 |
| » Starters: Dave McNally vs Jack Hamilton | Fourth | 5½ out |
| Former Tiger Earl Webb dies in Jamestown, TN at the age of 68. |
| Monday, May 24 |
| » Defeated White Sox (24-12), 8-3 | Comiskey Park I (1-0) | 20-17 | |
| » Starters: Mickey Lolich vs John Buzhardt | Fourth | 4½ out |
| Tuesday, May 25 |
| » Defeated White Sox (24-13), 7-5 | Comiskey Park I (2-0) | 21-17 | Won 2 |
| » Starters: Dave Wickersham vs Tommy John | Fourth | 3½ out |
| Thursday, May 27 |
| » Defeated Yankees (17-23), 4-1 | Tiger Stadium (9-11) | 22-17 | Won 3 |
| » Starters: Whitey Ford vs Joe Sparma | Third | 2½ out |
| Friday, May 28 |
| » Defeated Indians (19-18), 1-0 | Tiger Stadium (10-11) | 23-17 | Won 4 |
| » Starters: Ralph Terry vs Hank Aguirre | Third | 2½ out |
| Saturday, May 29 |
| » Defeated Indians (19-19), 1-0 | Tiger Stadium (11-11) | 24-17 | Won 5 |
| » Starters: Jack Kralick vs Mickey Lolich | Third | 2½ out |
| Sunday, May 30 |
| » Lost to Indians (20-19), 10-2 | Tiger Stadium (11-12) | 24-18 | |
| » Starters: Sam McDowell vs Phil Regan | Third | 3 out |
| Monday, May 31 |
| » Lost to Yankees (19-25), 3-1 | Yankee Stadium (0-1) | 24-19 | Lost 2 |
| » Manager: Chuck Dressen |
| » Starters: Denny McLain vs Whitey Ford | Third | 3 out |
| » Defeated Yankees (19-26), 5-1 | Yankee Stadium (1-1) | 25-19 | |
| » Starters: Joe Sparma vs Gil Blanco | Third | 3 out |
| Thursday, June 3 |
| » Major-league debuts: Bill Hands (Giants) |
| Friday, June 4 |
| » Lost to Indians (22-20), 7-6 | Cleveland Stadium (0-1) | 25-20 | |
| » Starters: Hank Aguirre vs Ralph Terry | Third | 5 out |
| Saturday, June 5 |
| » Lost to Indians (23-20), 2-1 | Cleveland Stadium (0-2) | 25-21 | Lost 2 |
| » Starters: Mickey Lolich vs Sam McDowell | Fourth | 5½ out |
| Sunday, June 6 |
| » Lost to Indians (24-20), 10-1 | Cleveland Stadium (0-3) | 25-22 | Lost 3 |
| » Starters: Joe Sparma vs Jack Kralick | Fifth | 6½ out |
| Monday, June 7 |
| » Defeated Angels (27-28), 6-5 | Dodger Stadium (2-2) | 26-22 | |
| » Starters: Denny McLain vs Dean Chance | Fourth | 5½ out |
| Tuesday, June 8 |
| » Lost to Angels (28-28), 3-1 | Dodger Stadium (2-3) | 26-23 | |
| » Starters: Dave Wickersham vs Fred Newman | Fourth | 6½ out |
| Future Tiger Kevin Ritz is born in Eatontown, NJ. |
| Wednesday, June 9 |
| » Defeated Angels (28-29), 4-2 | Dodger Stadium (3-3) | 27-23 | |
| » Starters: Hank Aguirre vs Marcelino Lopez | Fourth | 5½ out |
| Friday, June 11 |
| » Lost to Twins (33-18), 5-4 | Tiger Stadium (11-13) | 27-24 | |
| » Starters: Mudcat Grant vs Joe Sparma | Fifth | 7 out |
| » Lost to Twins (34-18), 5-4 | Tiger Stadium (11-14) | 27-25 | Lost 2 |
| » Starters: Mel Nelson vs Mickey Lolich | Fifth | 7 out |
| Saturday, June 12 |
| » Defeated Twins (34-19), 8-5 | Tiger Stadium (12-14) | 28-25 | |
| » Starters: Camilo Pascual vs Denny McLain | Fifth | 6 out |
| Sunday, June 13 |
| » Defeated Twins (34-20), 5-4 | Tiger Stadium (13-14) | 29-25 | Won 2 |
| » Starters: Jim Kaat vs Hank Aguirre | Fifth | 5 out |
| Tuesday, June 15 |
| » Defeated Red Sox (24-32), 6-5 | Tiger Stadium (14-14) | 30-25 | Won 3 |
| » Starters: Earl Wilson vs Dave Wickersham | Fifth | 5 out |
| Wednesday, June 16 |
| » Defeated Red Sox (24-33), 9-4 | Tiger Stadium (15-14) | 31-25 | Won 4 |
| » Starters: Dave Morehead vs Mickey Lolich | Fifth | 4 out |
| Thursday, June 17 |
| » Defeated Red Sox (24-34), 6-5 | Tiger Stadium (16-14) | 32-25 | Won 5 |
| » Starters: Jerry Stephenson vs Joe Sparma | Fifth | 4 out |
| Friday, June 18 |
| » Defeated Athletics (16-38), 3-1 | Tiger Stadium (17-14) | 33-25 | Won 6 |
| » Starters: John O'Donoghue vs Hank Aguirre | Fourth | 3 out |
| Saturday, June 19 |
| » Defeated Athletics (16-39), 8-2 | Tiger Stadium (18-14) | 34-25 | Won 7 |
| » Starters: Diego Segui vs Denny McLain | Fourth | 2 out |
| Sunday, June 20 |
| » Defeated Athletics (16-40), 12-8 | Tiger Stadium (19-14) | 35-25 | Won 8 |
| » Starters: Catfish Hunter vs Mickey Lolich | Fifth | 3 out |
| » Lost to Athletics (17-40), 2-1 | Tiger Stadium (19-15) | 35-26 | |
| » Starters: Rollie Sheldon vs Dave Wickersham | Fifth | 3 out |
| Tuesday, June 22 |
| » Lost to Angels (32-36), 3-0 | Tiger Stadium (19-16) | 35-27 | Lost 2 |
| » Starters: George Brunet vs Mickey Lolich | Fourth | 3 out |
| Wednesday, June 23 |
| » Defeated Angels (32-37), 2-0 | Tiger Stadium (20-16) | 36-27 | |
| » Starters: Rudy May vs Hank Aguirre | Fifth | 3 out |
| Thursday, June 24 |
| » Defeated Angels (32-38), 3-2 | Tiger Stadium (21-16) | 37-27 | Won 2 |
| » Starters: Fred Newman vs Denny McLain | Fourth | 2 out |
| Friday, June 25 |
| » Lost to Twins (40-25), 4-3 | Metropolitan Stadium (1-1) | 37-28 | |
| » Starters: Dave Wickersham vs Dave Boswell | Fourth | 3 out |
| Saturday, June 26 |
| » Defeated Twins (40-26), 5-2 | Metropolitan Stadium (2-1) | 38-28 | |
| » Starters: Mickey Lolich vs Bill Pleis | Fourth | 2 out |
| Sunday, June 27 |
| » Lost to Twins (41-26), 6-4 | Metropolitan Stadium (2-2) | 38-29 | |
| » Starters: Joe Sparma vs Mudcat Grant | Fourth | 4 out |
| » Lost to Twins (42-26), 6-5 | Metropolitan Stadium (2-3) | 38-30 | Lost 2 |
| » Starters: Hank Aguirre vs Mel Nelson | Fourth | 4 out |
| Monday, June 28 |
| » Defeated Orioles (40-31), 4-3 | Memorial Stadium (3-2) | 39-30 | |
| » Starters: Denny McLain vs Wally Bunker | Third | 3½ out |
| Tuesday, June 29 |
| » Lost to Orioles (41-31), 3-2 | Memorial Stadium (3-3) | 39-31 | |
| » Starters: Dave Wickersham vs Milt Pappas | Fifth | 4½ out |
| Thursday, July 1 |
| » Defeated Red Sox (29-43), 2-1 | Fenway Park (3-2) | 40-31 | |
| » Starters: Mickey Lolich vs Earl Wilson | Fifth | 4 out |
| Friday, July 2 |
| » Lost to Senators (31-46), 6-0 | Robert F. Kennedy Stadium (3-1) | 40-32 | |
| » Starters: Hank Aguirre vs Frank Kreutzer | Fifth | 5 out |
| Future Tiger Steve Sparks is born in Tulsa, OK. |
| Saturday, July 3 |
| » Defeated Senators (31-47), 1-0 | Robert F. Kennedy Stadium (4-1) | 41-32 | |
| » Starters: Denny McLain vs Pete Richert | Fourth | 4 out |
| Sunday, July 4 |
| » Lost to Senators (32-47), 6-3 | Robert F. Kennedy Stadium (4-2) | 41-33 | |
| » Starters: Dave Wickersham vs Buster Narum | Fourth | 5 out |
| Monday, July 5 |
| » Lost to Yankees (39-40), 7-2 | Tiger Stadium (21-17) | 41-34 | Lost 2 |
| » Starters: Whitey Ford vs Mickey Lolich | Fifth | 6 out |
| » Defeated Yankees (39-41), 5-4 | Tiger Stadium (22-17) | 42-34 | |
| » Starters: Steve Hamilton vs Joe Sparma | Fifth | 6 out |
| Tuesday, July 6 |
| » Defeated Yankees (39-42), 8-0 | Tiger Stadium (23-17) | 43-34 | Won 2 |
| » Starters: Mel Stottlemyre vs Denny McLain | Fifth | 6 out |
| Wednesday, July 7 |
| » Lost to Yankees (40-42), 4-3 | Tiger Stadium (23-18) | 43-35 | |
| » Starters: Al Downing vs Hank Aguirre | Fifth | 7 out |
| Thursday, July 8 |
| » Defeated Yankees (40-43), 6-1 | Tiger Stadium (24-18) | 44-35 | |
| » Starters: Pete Mikkelsen vs Mickey Lolich | Fifth | 6½ out |
| Friday, July 9 |
| » Defeated Athletics (22-53), 7-5 | Municipal Stadium (3-0) | 45-35 | Won 2 |
| » Starters: Joe Sparma vs Fred Talbot | Fifth | 6½ out |
| Saturday, July 10 |
| » Lost to Athletics (23-53), 4-3 | Municipal Stadium (3-1) | 45-36 | |
| » Starters: Denny McLain vs Rollie Sheldon | Fifth | 7 out |
| Future Tiger Buddy Groom is born in Dallas, TX. |
| Sunday, July 11 |
| » Defeated Athletics (23-54), 4-2 | Municipal Stadium (4-1) | 46-36 | |
| » Starters: Hank Aguirre vs Wes Stock | Fifth | 7 out |
| Monday, July 12 |
| Future Tiger Mike Munoz is born in Baldwin Park, CA. |
| Thursday, July 15 |
| » Defeated Orioles (49-36), 5-4 | Tiger Stadium (25-18) | 47-36 | Won 2 |
| » Starters: Steve Barber vs Mickey Lolich | Fifth | 6½ out |
| Future Tiger Scott Livingstone is born in Dallas, TX. |
| Friday, July 16 |
| » Lost to Orioles (50-36), 2-1 | Tiger Stadium (25-19) | 47-37 | |
| » Starters: Milt Pappas vs Denny McLain | Fifth | 6½ out |
| Sunday, July 18 |
| » Lost to Orioles (51-36), 4-1 | Tiger Stadium (25-20) | 47-38 | Lost 2 |
| » Starters: Wally Bunker vs Hank Aguirre | Third | 6½ out |
| Monday, July 19 |
| » Lost to Senators (38-53), 8-0 | Tiger Stadium (25-21) | 47-39 | Lost 3 |
| » Starters: Phil Ortega vs Mickey Lolich | Fourth | 7½ out |
| Tuesday, July 20 |
| » Defeated Senators (38-54), 2-0 | Tiger Stadium (26-21) | 48-39 | |
| » Starters: Howie Koplitz vs Dave Wickersham | Fourth | 6½ out |
| Wednesday, July 21 |
| » Defeated Indians (52-38), 10-5 | Tiger Stadium (27-21) | 49-39 | Won 2 |
| » Starters: Sam McDowell vs Mickey Lolich | Fifth | 6½ out |
| » Defeated Indians (52-39), 2-1 | Tiger Stadium (28-21) | 50-39 | Won 3 |
| » Starters: Sonny Siebert vs Denny McLain | Fifth | 6½ out |
| Friday, July 23 |
| » Defeated White Sox (51-40), 6-5 | Tiger Stadium (29-21) | 51-39 | Won 4 |
| » Starters: John Buzhardt vs Hank Aguirre | Fourth | 6 out |
| Saturday, July 24 |
| » Defeated White Sox (51-41), 7-4 | Tiger Stadium (30-21) | 52-39 | Won 5 |
| » Starters: Joe Horlen vs Dave Wickersham | Fourth | 5 out |
| Future Tiger Joe Oliver is born in Memphis, TN. |
| Sunday, July 25 |
| » Lost to White Sox (52-41), 10-6 | Tiger Stadium (30-22) | 52-40 | |
| » Starters: Tommy John vs Mickey Lolich | Fourth | 5½ out |
| » Defeated White Sox (52-42), 13-2 | Tiger Stadium (31-22) | 53-40 | |
| » Starters: Bruce Howard vs Denny McLain | Fourth | 5½ out |
| Future Tiger Torey Lovullo is born in Santa Monica, CA. |
| Tuesday, July 27 |
| » Lost to Yankees (49-51), 4-3 | Yankee Stadium (1-2) | 53-41 | |
| » Starters: Hank Aguirre vs Whitey Ford | Fourth | 6 out |
| » Defeated Yankees (49-52), 3-0 | Yankee Stadium (2-2) | 54-41 | |
| » Starters: Joe Sparma vs Jim Bouton | Fourth | 6 out |
| Wednesday, July 28 |
| » Defeated Yankees (49-53), 4-3 | Yankee Stadium (3-2) | 55-41 | Won 2 |
| » Starters: Dave Wickersham vs Jack Cullen | Fourth | 6 out |
| Thursday, July 29 |
| » Lost to Yankees (50-53), 7-3 | Yankee Stadium (3-3) | 55-42 | |
| » Starters: Denny McLain vs Mel Stottlemyre | Fourth | 6½ out |
| Friday, July 30 |
| » Defeated White Sox (53-45), 3-1 | Comiskey Park I (3-0) | 56-42 | |
| » Starters: Mickey Lolich vs Juan Pizarro | Third | 6½ out |
| Saturday, July 31 |
| » Lost to White Sox (54-45), 4-3 | Comiskey Park I (3-1) | 56-43 | |
| » Starters: Joe Sparma vs Frank Lary | Third | 7½ out |
| Sunday, August 1 |
| » Lost to White Sox (55-45), 1-0 | Comiskey Park I (3-2) | 56-44 | Lost 2 |
| » Starters: Hank Aguirre vs Joe Horlen | Fourth | 7 out |
| » Defeated White Sox (55-46), 2-1 | Comiskey Park I (4-2) | 57-44 | |
| » Starters: Dave Wickersham vs Tommy John | Fourth | 7 out |
| Monday, August 2 |
| » Lost to White Sox (56-46), 2-0 | Comiskey Park I (4-3) | 57-45 | |
| » Starters: Denny McLain vs Gary Peters | Third | 8 out |
| Tuesday, August 3 |
| » Defeated Indians (59-44), 12-7 | Cleveland Stadium (1-3) | 58-45 | |
| » Starters: Mickey Lolich vs Steve Hargan | Fourth | 7½ out |
| » Major-league debuts: Steve Hargan (Indians) |
| Wednesday, August 4 |
| » Lost to Indians (60-44), 4-1 | Cleveland Stadium (1-4) | 58-46 | |
| » Starters: Joe Sparma vs Sonny Siebert | Fourth | 8½ out |
| Thursday, August 5 |
| » Lost to Indians (61-44), 5-2 | Cleveland Stadium (1-5) | 58-47 | Lost 2 |
| » Starters: Dave Wickersham vs Sam McDowell | Fourth | 9½ out |
| Friday, August 6 |
| » Defeated Yankees (54-57), 5-4 | Tiger Stadium (32-22) | 59-47 | |
| » Starters: Jack Cullen vs Mickey Lolich | Fourth | 9½ out |
| Saturday, August 7 |
| » Lost to Yankees (55-57), 6-5 | Tiger Stadium (32-23) | 59-48 | |
| » Starters: Mel Stottlemyre vs Hank Aguirre | Fourth | 10½ out |
| Sunday, August 8 |
| » Lost to Yankees (56-57), 6-5 | Tiger Stadium (32-24) | 59-49 | Lost 2 |
| » Starters: Al Downing vs Denny McLain | Fourth | 11½ out |
| Tuesday, August 10 |
| » Defeated Athletics (38-69), 3-0 | Tiger Stadium (33-24) | 60-49 | |
| » Starters: Fred Talbot vs Dave Wickersham | Fourth | 11½ out |
| Wednesday, August 11 |
| » Defeated Athletics (38-70), 6-2 | Tiger Stadium (34-24) | 61-49 | Won 2 |
| » Starters: Catfish Hunter vs Joe Sparma | Fourth | 10 out |
| » Defeated Athletics (38-71), 5-4 | Tiger Stadium (35-24) | 62-49 | Won 3 |
| » Starters: Rollie Sheldon vs Mickey Lolich | Fourth | 10 out |
| Thursday, August 12 |
| » Defeated Athletics (38-72), 11-1 | Tiger Stadium (36-24) | 63-49 | Won 4 |
| » Starters: Diego Segui vs Hank Aguirre | Third | 10 out |
| Friday, August 13 |
| » Defeated Angels (52-62), 2-1 | Tiger Stadium (37-24) | 64-49 | Won 5 |
| » Starters: Dean Chance vs Denny McLain | Third | 9 out |
| Saturday, August 14 |
| » Lost to Angels (53-62), 5-2 | Tiger Stadium (37-25) | 64-50 | |
| » Starters: Marcelino Lopez vs Dave Wickersham | Fourth | 9 out |
| Sunday, August 15 |
| » Defeated Angels (53-63), 9-2 | Tiger Stadium (38-25) | 65-50 | |
| » Starters: Ken McBride vs Joe Sparma | Second | 8 out |
| » Defeated Angels (53-64), 9-5 | Tiger Stadium (39-25) | 66-50 | Won 2 |
| » Starters: George Brunet vs Mickey Lolich | Second | 8 out |
| Tuesday, August 17 |
| » Defeated Twins (75-44), 7-4 | Tiger Stadium (40-25) | 67-50 | Won 3 |
| » Starters: Jim Merritt vs Hank Aguirre | Second | 7 out |
| Thursday, August 19 |
| » Lost to Twins (76-44), 8-3 | Tiger Stadium (40-26) | 67-51 | |
| » Starters: Mudcat Grant vs Dave Wickersham | Third | 9 out |
| » Lost to Twins (77-44), 2-1 | Tiger Stadium (40-27) | 67-52 | Lost 2 |
| » Starters: Jim Kaat vs Mickey Lolich | Third | 9 out |
| Friday, August 20 |
| » Defeated Red Sox (44-76), 2-0 | Fenway Park (4-2) | 68-52 | |
| » Starters: Denny McLain vs Bill Monbouquette | Third | 8 out |
| » Defeated Red Sox (44-77), 3-2 | Fenway Park (5-2) | 69-52 | Won 2 |
| » Starters: Joe Sparma vs Earl Wilson | Third | 8 out |
| Saturday, August 21 |
| » Lost to Red Sox (45-77), 13-10 | Fenway Park (5-3) | 69-53 | |
| » Starters: Hank Aguirre vs Dave Morehead | Third | 9 out |
| Sunday, August 22 |
| » Defeated Red Sox (45-78), 2-1 | Fenway Park (6-3) | 70-53 | |
| » Starters: Joe Sparma vs Dennis Bennett | Third | 8 out |
| Monday, August 23 |
| » Lost to Athletics (42-80), 4-3 | Municipal Stadium (4-2) | 70-54 | |
| » Starters: Mickey Lolich vs Rollie Sheldon | Third | 9 out |
| Tuesday, August 24 |
| » Defeated Athletics (42-81), 8-2 | Municipal Stadium (5-2) | 71-54 | |
| » Starters: Denny McLain vs Lew Krausse | Third | 8 out |
| Wednesday, August 25 |
| » Lost to Athletics (43-81), 5-0 | Municipal Stadium (5-3) | 71-55 | |
| » Starters: Joe Sparma vs Catfish Hunter | Third | 9 out |
| Thursday, August 26 |
| » Lost to Athletics (44-81), 5-3 | Municipal Stadium (5-4) | 71-56 | Lost 2 |
| » Starters: Hank Aguirre vs Fred Talbot | Fourth | 10 out |
| Friday, August 27 |
| » Lost to Angels (59-70), 3-2 | Dodger Stadium (3-4) | 71-57 | Lost 3 |
| » Starters: Mickey Lolich vs Dean Chance | Fourth | 11 out |
| Saturday, August 28 |
| » Lost to Angels (60-70), 4-3 | Dodger Stadium (3-5) | 71-58 | Lost 4 |
| » Starters: Denny McLain vs Marcelino Lopez | Fifth | 11 out |
| Sunday, August 29 |
| » Defeated Angels (60-71), 2-1 | Dodger Stadium (4-5) | 72-58 | |
| » Starters: Joe Sparma vs Fred Newman | Fourth | 10 out |
| Monday, August 30 |
| » Lost to Twins (84-49), 3-2 | Metropolitan Stadium (2-4) | 72-59 | |
| » Starters: Hank Aguirre vs Jim Kaat | Fifth | 11 out |
| Tuesday, August 31 |
| » Defeated Twins (84-50), 7-6 | Metropolitan Stadium (3-4) | 73-59 | |
| » Starters: Mickey Lolich vs Mudcat Grant | Fifth | 10 out |
| Wednesday, September 1 |
| » Lost to Twins (85-50), 5-2 | Metropolitan Stadium (3-5) | 73-60 | |
| » Starters: Dave Wickersham vs Jim Perry | Fifth | 11 out |
| Thursday, September 2 |
| » Defeated Twins (85-51), 5-4 | Metropolitan Stadium (4-5) | 74-60 | |
| » Starters: Joe Sparma vs Jim Merritt | Fourth | 10 out |
| Former Tiger Joe Hoover dies in Los Angeles, CA at the age of 51. |
| Friday, September 3 |
| » Defeated Senators (60-76), 10-2 | Tiger Stadium (41-27) | 75-60 | Won 2 |
| » Starters: Buster Narum vs Hank Aguirre | Third | 10 out |
| Saturday, September 4 |
| » Lost to Senators (61-76), 1-0 | Tiger Stadium (41-28) | 75-61 | |
| » Starters: Jim Duckworth vs Dave Wickersham | Fourth | 10 out |
| Sunday, September 5 |
| » Lost to Senators (62-76), 2-1 | Tiger Stadium (41-29) | 75-62 | Lost 2 |
| » Starters: Pete Richert vs Mickey Lolich | Fourth | 9½ out |
| » Defeated Senators (62-77), 11-2 | Tiger Stadium (42-29) | 76-62 | |
| » Starters: Phil Ortega vs Phil Regan | Fourth | 9½ out |
| Future Tiger Rob Richie is born in Reno, NV. |
| Monday, September 6 |
| » Lost to Red Sox (55-86), 4-1 | Tiger Stadium (42-30) | 76-63 | |
| » Starters: Earl Wilson vs Joe Sparma | Fifth | 10 out |
| » Major-league debuts: John Hiller (Tigers) |
| Tuesday, September 7 |
| » Defeated Red Sox (55-87), 5-3 | Tiger Stadium (43-30) | 77-63 | |
| » Starters: Bill Monbouquette vs Julio Navarro | Fifth | 9½ out |
| » Major-league debuts: Wayne Redmond (Tigers) |
| Wednesday, September 8 |
| » Lost to Orioles (80-59), 2-0 | Tiger Stadium (43-31) | 77-64 | |
| » Starters: Steve Barber vs Hank Aguirre | Fifth | 10 out |
| » Defeated Orioles (80-60), 5-0 | Tiger Stadium (44-31) | 78-64 | |
| » Starters: Darold Knowles vs Dave Wickersham | Fifth | 10 out |
| » Major-league debuts: Ed Barnowski (Orioles) |
| Thursday, September 9 |
| » Major-league debuts: Ron Tompkins (Athletics) |
| Friday, September 10 |
| » Defeated Indians (77-64), 2-0 | Cleveland Stadium (2-5) | 79-64 | Won 2 |
| » Starters: Mickey Lolich vs Sonny Siebert | Fourth | 10½ out |
| Saturday, September 11 |
| » Defeated Indians (77-65), 5-3 | Cleveland Stadium (3-5) | 80-64 | Won 3 |
| » Starters: Joe Sparma vs Luis Tiant | Fourth | 10½ out |
| Tuesday, September 14 |
| » Lost to Orioles (82-62), 5-3 | Memorial Stadium (3-4) | 80-65 | |
| » Starters: Hank Aguirre vs Steve Barber | Fourth | 11½ out |
| » Defeated Orioles (82-63), 7-1 | Memorial Stadium (4-4) | 81-65 | |
| » Starters: Dave Wickersham vs Milt Pappas | Fourth | 11½ out |
| Wednesday, September 15 |
| » Lost to Orioles (83-63), 3-2 | Memorial Stadium (4-5) | 81-66 | |
| » Starters: Denny McLain vs Dave McNally | Fourth | 12½ out |
| Thursday, September 16 |
| » Major-league debuts: Jim Ray (Astros) |
| Friday, September 17 |
| » Defeated Yankees (73-77), 4-3 | Yankee Stadium (4-3) | 82-66 | |
| » Starters: Mickey Lolich vs Whitey Ford | Fourth | 11½ out |
| Saturday, September 18 |
| » Defeated Yankees (73-78), 4-3 | Yankee Stadium (5-3) | 83-66 | Won 2 |
| » Starters: Joe Sparma vs Al Downing | Fourth | 11½ out |
| Sunday, September 19 |
| » Lost to Yankees (74-78), 3-0 | Yankee Stadium (5-4) | 83-67 | |
| » Starters: Dave Wickersham vs Rich Beck | Fourth | 12½ out |
| Monday, September 20 |
| » Lost to Indians (79-70), 5-4 | Cleveland Stadium (3 |
