| Sunday, January 3 |
| Future Pirate Mark Dewey is born in Grand Rapids, MI. Future Pirate Luis Sojo is born in Caracas, Venezuela. |
| Saturday, January 16 |
| Former Pirate Jimmy Williams dies in St.Petersburg, FL at the age of 89. |
| Monday, February 8 |
| Former Pirate Ray Kremer dies in Pinole, CA at the age of 72. |
| Friday, February 12 |
| Future Pirate Stan Fansler is born in Elkins, WV. |
| Saturday, February 20 |
| Future Pirate Tony Menendez is born in Havana, Cuba. |
| Monday, March 1 |
| Former Pirate Maurice Van Robays dies in Detroit, MI at the age of 51. |
| Wednesday, March 17 |
| Future Pirate John Smiley is born in Phoenixville, PA. |
| Sunday, April 11 |
| Future Pirate Turner Ward is born in Orlando, FL. |
| Monday, April 12 |
| » Defeated Giants (0-1), 1-0 | Forbes Field (1-0) | 1-0 | |
| » Starters: Juan Marichal vs Bob Veale | First | -- |
| Tuesday, April 13 |
| » Defeated Giants (0-2), 5-2 | Forbes Field (2-0) | 2-0 | Won 2 |
| » Starters: Jack Sanford vs Bob Friend | First | -- |
| Wednesday, April 14 |
| » Lost to Dodgers (2-0), 3-1 | Forbes Field (2-1) | 2-1 | |
| » Starters: Claude Osteen vs Joe Gibbon | Second | ½ out |
| Saturday, April 17 |
| » Defeated Astros (1-3), 3-2 | Forbes Field (3-1) | 3-1 | |
| » Starters: Don Nottebart vs Bob Veale | First | -- |
| Sunday, April 18 |
| » Lost to Astros (2-3), 3-1 | Forbes Field (3-2) | 3-2 | |
| » Starters: Bob Bruce vs Vern Law | Second | 1 out |
| » Defeated Astros (2-4), 5-4 | Forbes Field (4-2) | 4-2 | |
| » Starters: Don Larsen vs Don Cardwell | Second | 1 out |
| Tuesday, April 20 |
| » Defeated Giants (3-4), 3-1 | Candlestick Park (1-0) | 5-2 | Won 2 |
| » Starters: Bob Friend vs Bobby Bolin | First | -- |
| » Major-league debuts: Bob Schroder (Giants) |
| Wednesday, April 21 |
| » Lost to Giants (4-4), 3-2 | Candlestick Park (1-1) | 5-3 | |
| » Starters: Joe Gibbon vs Juan Marichal | Third | ½ out |
| Friday, April 23 |
| » Lost to Astros (4-6), 4-3 | Astrodome (0-1) | 5-4 | Lost 2 |
| » Starters: Bob Veale vs Bob Bruce | Third | 1½ out |
| Saturday, April 24 |
| » Lost to Astros (5-6), 5-0 | Astrodome (0-2) | 5-5 | Lost 3 |
| » Starters: Vern Law vs Turk Farrell | Fourth | 2½ out |
| Sunday, April 25 |
| » Lost to Astros (6-6), 5-4 | Astrodome (0-3) | 5-6 | Lost 4 |
| » Starters: Don Cardwell vs Ken Johnson | Seventh | 2½ out |
| Monday, April 26 |
| » Lost to Astros (7-6), 2-0 | Astrodome (0-4) | 5-7 | Lost 5 |
| » Starters: Bob Friend vs Dave Giusti | Seventh | 2½ out |
| Tuesday, April 27 |
| » Lost to Dodgers (8-4), 5-4 | Dodger Stadium (0-1) | 5-8 | Lost 6 |
| » Starters: Joe Gibbon vs Johnny Podres | Ninth | 3½ out |
| Future Pirate Paul Miller is born in Burlington, WI. |
| Wednesday, April 28 |
| » Defeated Dodgers (8-5), 2-0 | Dodger Stadium (1-1) | 6-8 | |
| » Starters: Bob Veale vs Claude Osteen | Seventh | 3 out |
| Friday, April 30 |
| » Lost to Cardinals (5-8), 3-2 | Sportsman's Park III (0-1) | 6-9 | |
| » Starters: Vern Law vs Ray Sadecki | Eighth | 4 out |
| Saturday, May 1 |
| » Lost to Cardinals (6-8), 3-2 | Sportsman's Park III (0-2) | 6-10 | Lost 2 |
| » Starters: Don Cardwell vs Tracy Stallard | Ninth | 5 out |
| Sunday, May 2 |
| » Lost to Cardinals (7-8), 9-5 | Sportsman's Park III (0-3) | 6-11 | Lost 3 |
| » Starters: Bob Friend vs Bob Gibson | Eighth | 6½ out |
| » Lost to Cardinals (8-8), 5-4 | Sportsman's Park III (0-4) | 6-12 | Lost 4 |
| » Starters: Bob Veale vs Bob Purkey | Eighth | 6½ out |
| Former Pirate Wally Hood dies in Hollywood, CA at the age of 71. |
| Tuesday, May 4 |
| » Defeated Cubs (8-9), 6-3 | Wrigley Field (1-0) | 7-12 | |
| » Starters: Joe Gibbon vs Cal Koonce | Eighth | 5½ out |
| Wednesday, May 5 |
| » Lost to Cubs (9-9), 3-1 | Wrigley Field (1-1) | 7-13 | |
| » Starters: Vern Law vs Bob Buhl | Eighth | 6½ out |
| Thursday, May 6 |
| » Lost to Cubs (10-9), 5-3 | Wrigley Field (1-2) | 7-14 | Lost 2 |
| » Starters: Don Cardwell vs Larry Jackson | Eighth | 7½ out |
| Friday, May 7 |
| » Defeated Reds (12-9), 5-4 | Forbes Field (5-2) | 8-14 | |
| » Starters: Sammy Ellis vs Bob Friend | Eighth | 7½ out |
| Saturday, May 8 |
| » Lost to Reds (13-9), 10-1 | Forbes Field (5-3) | 8-15 | |
| » Starters: Jim Maloney vs Bob Veale | Eighth | 8½ out |
| Sunday, May 9 |
| » Lost to Reds (14-9), 5-3 | Forbes Field (5-4) | 8-16 | Lost 2 |
| » Starters: Joey Jay vs Joe Gibbon | Tenth | 8½ out |
| Tuesday, May 11 |
| » Defeated Braves (10-11), 4-3 | Forbes Field (6-4) | 9-16 | |
| » Starters: Wade Blasingame vs Don Cardwell | Eighth | 8 out |
| Wednesday, May 12 |
| » Lost to Braves (11-11), 5-4 | Forbes Field (6-5) | 9-17 | |
| » Starters: Denny Lemaster vs Bob Friend | Ninth | 9 out |
| Thursday, May 13 |
| » Lost to Braves (12-11), 5-4 | Forbes Field (6-6) | 9-18 | Lost 2 |
| » Starters: Tony Cloninger vs Bob Veale | Tenth | 10 out |
| Friday, May 14 |
| » Lost to Cardinals (12-14), 8-7 | Forbes Field (6-7) | 9-19 | Lost 3 |
| » Starters: Ray Sadecki vs Joe Gibbon | Tenth | 10 out |
| Saturday, May 15 |
| » Lost to Cardinals (13-14), 5-1 | Forbes Field (6-8) | 9-20 | Lost 4 |
| » Starters: Tracy Stallard vs Vern Law | Tenth | 11 out |
| Sunday, May 16 |
| » Lost to Cardinals (14-14), 6-3 | Forbes Field (6-9) | 9-21 | Lost 5 |
| » Starters: Bob Gibson vs Don Cardwell | Ninth | 12 out |
| » Lost to Cardinals (15-14), 5-1 | Forbes Field (6-10) | 9-22 | Lost 6 |
| » Starters: Ray Washburn vs Bob Veale | Ninth | 12 out |
| Wednesday, May 19 |
| » Lost to Reds (18-13), 3-1 | Crosley Field (0-1) | 9-23 | Lost 7 |
| » Starters: Joe Gibbon vs Jim Maloney | Ninth | 13 out |
| Thursday, May 20 |
| » Lost to Reds (19-13), 11-3 | Crosley Field (0-2) | 9-24 | Lost 8 |
| » Starters: Bob Friend vs Sammy Ellis | Ninth | 13½ out |
| Friday, May 21 |
| » Defeated Braves (16-14), 6-1 | County Stadium (1-0) | 10-24 | |
| » Starters: Vern Law vs Denny Lemaster | Tenth | 12½ out |
| Saturday, May 22 |
| » Defeated Braves (16-15), 9-4 | County Stadium (2-0) | 11-24 | Won 2 |
| » Starters: Don Cardwell vs Tony Cloninger | Tenth | 12½ out |
| Sunday, May 23 |
| » Defeated Braves (16-16), 10-1 | County Stadium (3-0) | 12-24 | Won 3 |
| » Starters: Bob Veale vs Bob Sadowski | Tenth | 11½ out |
| Monday, May 24 |
| » Defeated Cubs (18-19), 6-4 | Forbes Field (7-10) | 13-24 | Won 4 |
| » Starters: Lew Burdette vs Joe Gibbon | Tenth | 10½ out |
| Tuesday, May 25 |
| » Defeated Cubs (18-20), 7-6 | Forbes Field (8-10) | 14-24 | Won 5 |
| » Starters: Larry Jackson vs Bob Friend | Tenth | 10½ out |
| » Major-league debuts: Frank Carpin (Pirates) |
| Wednesday, May 26 |
| » Defeated Phillies (18-22), 5-3 | Shibe Park (1-0) | 15-24 | Won 6 |
| » Starters: Don Cardwell vs Art Mahaffey | Ninth | 9½ out |
| Thursday, May 27 |
| Future Pirate Jacob Brumfield is born in Bogalusa, LA. |
| Friday, May 28 |
| » Defeated Mets (16-26), 6-1 | Shea Stadium (1-0) | 16-24 | Won 7 |
| » Starters: Bob Veale vs Warren Spahn | Eighth | 9 out |
| Saturday, May 29 |
| » Defeated Mets (16-27), 7-4 | Shea Stadium (2-0) | 17-24 | Won 8 |
| » Starters: Joe Gibbon vs Frank Lary | Ninth | 9 out |
| Future Pirate Charlie Hayes is born in Hattiesburg, MS. |
| Sunday, May 30 |
| » Defeated Mets (16-28), 9-1 | Shea Stadium (3-0) | 18-24 | Won 9 |
| » Starters: Bob Friend vs Al Jackson | Eighth | 8½ out |
| » Defeated Mets (16-29), 12-0 | Shea Stadium (4-0) | 19-24 | Won 10 |
| » Starters: Vern Law vs Tom Parsons | Eighth | 8½ out |
| Monday, May 31 |
| » Defeated Phillies (20-24), 5-2 | Forbes Field (9-10) | 20-24 | Won 11 |
| » Starters: Chris Short vs Don Cardwell | Seventh | 8 out |
| Tuesday, June 1 |
| » Defeated Phillies (20-25), 4-0 | Forbes Field (10-10) | 21-24 | Won 12 |
| » Starters: Art Mahaffey vs Bob Veale | Seventh | 7½ out |
| Thursday, June 3 |
| » Lost to Mets (19-29), 8-6 | Forbes Field (10-11) | 21-25 | |
| » Starters: Galen Cisco vs Joe Gibbon | Seventh | 9 out |
| Friday, June 4 |
| » Lost to Mets (20-29), 2-1 | Forbes Field (10-12) | 21-26 | Lost 2 |
| » Starters: Jack Fisher vs Bob Friend | Eighth | 9 out |
| Saturday, June 5 |
| » Defeated Mets (20-30), 9-0 | Forbes Field (11-12) | 22-26 | |
| » Starters: Gary Kroll vs Vern Law | Seventh | 8 out |
| Sunday, June 6 |
| » Defeated Mets (20-31), 5-3 | Forbes Field (12-12) | 23-26 | Won 2 |
| » Starters: Al Jackson vs Don Cardwell | Seventh | 7 out |
| » Defeated Mets (20-32), 3-0 | Forbes Field (13-12) | 24-26 | Won 3 |
| » Starters: Warren Spahn vs Bob Veale | Seventh | 7 out |
| Tuesday, June 8 |
| » Defeated Astros (26-29), 7-6 | Forbes Field (14-12) | 25-26 | Won 4 |
| » Starters: Turk Farrell vs Bob Friend | Fifth | 7½ out |
| Wednesday, June 9 |
| » Defeated Astros (26-30), 11-3 | Forbes Field (15-12) | 26-26 | Won 5 |
| » Starters: Don Nottebart vs Vern Law | Fifth | 6½ out |
| Thursday, June 10 |
| » Defeated Astros (26-31), 4-2 | Forbes Field (16-12) | 27-26 | Won 6 |
| » Starters: Bob Bruce vs Bob Veale | Fifth | 5½ out |
| Friday, June 11 |
| » Defeated Giants (30-25), 5-3 | Forbes Field (17-12) | 28-26 | Won 7 |
| » Starters: Bill Hands vs Don Cardwell | Fifth | 5½ out |
| Saturday, June 12 |
| » Lost to Giants (31-25), 4-0 | Forbes Field (17-13) | 28-27 | |
| » Starters: Bob Shaw vs Bob Friend | Fifth | 6½ out |
| Sunday, June 13 |
| » Defeated Giants (31-26), 2-1 | Forbes Field (18-13) | 29-27 | |
| » Starters: Gaylord Perry vs Vern Law | Fifth | 7 out |
| Monday, June 14 |
| » Lost to Cardinals (28-30), 5-2 | Sportsman's Park III (0-5) | 29-28 | |
| » Starters: Bob Veale vs Steve Carlton | Fourth | 7½ out |
| Tuesday, June 15 |
| » Defeated Cardinals (28-31), 10-6 | Sportsman's Park III (1-5) | 30-28 | |
| » Starters: Don Cardwell vs Ray Sadecki | Fourth | 6½ out |
| Wednesday, June 16 |
| » Defeated Cardinals (28-32), 10-9 | Sportsman's Park III (2-5) | 31-28 | Won 2 |
| » Starters: Bob Friend vs Ray Washburn | Fifth | 6½ out |
| Thursday, June 17 |
| » Defeated Cardinals (28-33), 4-1 | Sportsman's Park III (3-5) | 32-28 | Won 3 |
| » Starters: Vern Law vs Bob Gibson | Fourth | 6½ out |
| Friday, June 18 |
| » Lost to Astros (28-37), 5-1 | Astrodome (0-5) | 32-29 | |
| » Starters: Bob Veale vs Bob Bruce | Fifth | 6½ out |
| Saturday, June 19 |
| » Defeated Astros (28-38), 5-3 | Astrodome (1-5) | 33-29 | |
| » Starters: Don Cardwell vs Claude Raymond | Fifth | 6½ out |
| Sunday, June 20 |
| » Lost to Giants (35-28), 4-3 | Candlestick Park (1-2) | 33-30 | |
| » Starters: Bob Friend vs Bob Shaw | Fifth | 7½ out |
| » Lost to Giants (36-28), 7-3 | Candlestick Park (1-3) | 33-31 | Lost 2 |
| » Starters: Don Schwall vs Bobby Bolin | Fifth | 7½ out |
| Tuesday, June 22 |
| » Defeated Giants (36-29), 6-0 | Candlestick Park (2-3) | 34-31 | |
| » Starters: Vern Law vs Gaylord Perry | Fifth | 7 out |
| Wednesday, June 23 |
| » Lost to Giants (37-29), 6-1 | Candlestick Park (2-4) | 34-32 | |
| » Starters: Bob Veale vs Jack Sanford | Fifth | 7½ out |
| Thursday, June 24 |
| » Defeated Dodgers (43-27), 13-3 | Dodger Stadium (2-1) | 35-32 | |
| » Starters: Don Cardwell vs Don Drysdale | Fifth | 6½ out |
| Friday, June 25 |
| » Lost to Dodgers (44-27), 4-1 | Dodger Stadium (2-2) | 35-33 | |
| » Starters: Bob Friend vs Sandy Koufax | Fifth | 7½ out |
| Saturday, June 26 |
| » Defeated Dodgers (44-28), 6-1 | Dodger Stadium (3-2) | 36-33 | |
| » Starters: Vern Law vs Claude Osteen | Fifth | 6½ out |
| Sunday, June 27 |
| » Defeated Dodgers (44-29), 10-2 | Dodger Stadium (4-2) | 37-33 | Won 2 |
| » Starters: Bob Veale vs Johnny Podres | Fifth | 5½ out |
| Monday, June 28 |
| » Defeated Reds (42-30), 5-4 | Forbes Field (19-13) | 38-33 | Won 3 |
| » Starters: Jim O'Toole vs Don Cardwell | Fourth | 4½ out |
| Tuesday, June 29 |
| » Defeated Reds (42-31), 2-1 | Forbes Field (20-13) | 39-33 | Won 4 |
| » Starters: Sammy Ellis vs Bob Friend | Fifth | 5 out |
| » Lost to Reds (43-31), 7-5 | Forbes Field (20-14) | 39-34 | |
| » Starters: Joe Nuxhall vs Joe Gibbon | Fifth | 5 out |
| Wednesday, June 30 |
| » Lost to Cardinals (34-41), 7-1 | Forbes Field (20-15) | 39-35 | Lost 2 |
| » Starters: Ray Washburn vs Vern Law | Sixth | 5½ out |
| Thursday, July 1 |
| » Lost to Cardinals (35-41), 7-6 | Forbes Field (20-16) | 39-36 | Lost 3 |
| » Starters: Curt Simmons vs Bob Veale | Sixth | 5½ out |
| Friday, July 2 |
| » Defeated Braves (37-35), 8-3 | Forbes Field (21-16) | 40-36 | |
| » Starters: Tony Cloninger vs Don Cardwell | Fifth | 4½ out |
| Saturday, July 3 |
| » Defeated Braves (37-36), 9-5 | Forbes Field (22-16) | 41-36 | Won 2 |
| » Starters: Bob Sadowski vs Bob Friend | Fifth | 4½ out |
| Sunday, July 4 |
| » Lost to Braves (38-36), 5-2 | Forbes Field (22-17) | 41-37 | |
| » Starters: Hank Fischer vs Vern Law | Fourth | 4½ out |
| Monday, July 5 |
| » Lost to Phillies (41-36), 3-1 | Shibe Park (1-1) | 41-38 | Lost 2 |
| » Starters: Bob Veale vs Jim Bunning | Fifth | 5 out |
| » Lost to Phillies (42-36), 6-2 | Shibe Park (1-2) | 41-39 | Lost 3 |
| » Starters: Wilbur Wood vs Art Mahaffey | Fifth | 5 out |
| Tuesday, July 6 |
| » Defeated Phillies (42-37), 8-4 | Shibe Park (2-2) | 42-39 | |
| » Starters: Don Cardwell vs Ray Culp | Fifth | 5 out |
| Wednesday, July 7 |
| » Lost to Phillies (43-37), 1-0 | Shibe Park (2-3) | 42-40 | |
| » Starters: Bob Friend vs Chris Short | Sixth | 5 out |
| Thursday, July 8 |
| » Lost to Dodgers (49-36), 9-4 | Forbes Field (22-18) | 42-41 | Lost 2 |
| » Starters: Claude Osteen vs Vern Law | Sixth | 6 out |
| Friday, July 9 |
| » Defeated Dodgers (49-37), 4-1 | Forbes Field (23-18) | 43-41 | |
| » Starters: Johnny Podres vs Bob Veale | Sixth | 5½ out |
| Saturday, July 10 |
| » Lost to Dodgers (50-37), 8-4 | Forbes Field (23-19) | 43-42 | |
| » Starters: Don Drysdale vs Don Cardwell | Fifth | 6½ out |
| Sunday, July 11 |
| » Lost to Dodgers (51-37), 4-2 | Forbes Field (23-20) | 43-43 | Lost 2 |
| » Starters: Sandy Koufax vs Joe Gibbon | Sixth | 6 out |
| » Defeated Dodgers (51-38), 4-3 | Forbes Field (24-20) | 44-43 | |
| » Starters: Claude Osteen vs Bob Friend | Sixth | 6 out |
| Thursday, July 15 |
| » Lost to Braves (43-40), 9-6 | County Stadium (3-1) | 44-44 | |
| » Starters: Vern Law vs Ken Johnson | Sixth | 7 out |
| Friday, July 16 |
| » Lost to Braves (44-40), 12-2 | County Stadium (3-2) | 44-45 | Lost 2 |
| » Starters: Bob Veale vs Wade Blasingame | Sixth | 8 out |
| Saturday, July 17 |
| » Lost to Braves (45-40), 6-5 | County Stadium (3-3) | 44-46 | Lost 3 |
| » Starters: Don Cardwell vs Bob Sadowski | Seventh | 9 out |
| Sunday, July 18 |
| » Defeated Reds (51-38), 6-5 | Crosley Field (1-2) | 45-46 | |
| » Starters: Bob Friend vs Jim Maloney | Seventh | 9½ out |
| » Lost to Reds (52-38), 8-4 | Crosley Field (1-3) | 45-47 | |
| » Starters: Joe Gibbon vs Joey Jay | Seventh | 9½ out |
| Monday, July 19 |
| » Defeated Reds (52-39), 3-1 | Crosley Field (2-3) | 46-47 | |
| » Starters: Vern Law vs Joe Nuxhall | Seventh | 9½ out |
| Tuesday, July 20 |
| » Defeated Reds (52-40), 8-6 | Crosley Field (3-3) | 47-47 | Won 2 |
| » Starters: Bob Veale vs Sammy Ellis | Seventh | 9½ out |
| Wednesday, July 21 |
| » Lost to Mets (30-63), 1-0 | Forbes Field (24-21) | 47-48 | |
| » Starters: Al Jackson vs Don Cardwell | Seventh | 9½ out |
| Friday, July 23 |
| » Defeated Cubs (44-52), 6-0 | Wrigley Field (2-2) | 48-48 | |
| » Starters: Bob Friend vs Dick Ellsworth | Sixth | 8 out |
| Saturday, July 24 |
| » Defeated Cubs (44-53), 8-5 | Wrigley Field (3-2) | 49-48 | Won 2 |
| » Starters: Vern Law vs Larry Jackson | Sixth | 7 out |
| Future Pirate Joe Oliver is born in Memphis, TN. |
| Sunday, July 25 |
| » Defeated Cubs (44-54), 3-2 | Wrigley Field (4-2) | 50-48 | Won 3 |
| » Starters: Bob Veale vs Cal Koonce | Sixth | 7½ out |
| » Lost to Cubs (45-54), 5-0 | Wrigley Field (4-3) | 50-49 | |
| » Starters: Don Cardwell vs Bill Faul | Sixth | 7½ out |
| Tuesday, July 27 |
| » Lost to Phillies (50-47), 3-1 | Forbes Field (24-22) | 50-50 | Lost 2 |
| » Starters: Chris Short vs Bob Friend | Sixth | 8½ out |
| » Defeated Phillies (50-48), 3-2 | Forbes Field (25-22) | 51-50 | |
| » Starters: Ray Herbert vs Tommie Sisk | Sixth | 8½ out |
| Wednesday, July 28 |
| » Lost to Phillies (51-48), 1-0 | Forbes Field (25-23) | 51-51 | |
| » Starters: Jim Bunning vs Vern Law | Seventh | 8½ out |
| Thursday, July 29 |
| » Lost to Phillies (52-48), 5-0 | Forbes Field (25-24) | 51-52 | Lost 2 |
| » Starters: Ray Culp vs Bob Veale | Seventh | 9 out |
| Friday, July 30 |
| » Defeated Cubs (49-56), 3-1 | Forbes Field (26-24) | 52-52 | |
| » Starters: Ernie Broglio vs Don Cardwell | Sixth | 9 out |
| Saturday, July 31 |
| » Lost to Cubs (50-56), 7-6 | Forbes Field (26-25) | 52-53 | |
| » Starters: Bob Buhl vs Tommie Sisk | Seventh | 9 out |
| Sunday, August 1 |
| » Defeated Cubs (50-57), 8-2 | Forbes Field (27-25) | 53-53 | |
| » Starters: Dick Ellsworth vs Al McBean | Sixth | 8½ out |
| » Defeated Cubs (50-58), 3-1 | Forbes Field (28-25) | 54-53 | Won 2 |
| » Starters: Larry Jackson vs Joe Gibbon | Sixth | 8½ out |
| Tuesday, August 3 |
| » Defeated Mets (34-72), 7-0 | Shea Stadium (5-0) | 55-53 | Won 3 |
| » Starters: Vern Law vs Galen Cisco | Sixth | 7½ out |
| Wednesday, August 4 |
| » Defeated Mets (34-73), 3-0 | Shea Stadium (6-0) | 56-53 | Won 4 |
| » Starters: Bob Veale vs Jack Fisher | Sixth | 7 out |
| Thursday, August 5 |
| » Defeated Mets (34-74), 11-3 | Shea Stadium (7-0) | 57-53 | Won 5 |
| » Starters: Don Cardwell vs Al Jackson | Sixth | 7 out |
| Friday, August 6 |
| » Lost to Phillies (57-50), 4-0 | Shibe Park (2-4) | 57-54 | |
| » Starters: Bob Friend vs Jim Bunning | Sixth | 7 out |
| Saturday, August 7 |
| » Defeated Phillies (57-51), 4-3 | Shibe Park (3-4) | 58-54 | |
| » Starters: Vern Law vs Ray Culp | Sixth | 7 out |
| Sunday, August 8 |
| » Defeated Phillies (57-52), 7-1 | Shibe Park (4-4) | 59-54 | Won 2 |
| » Starters: Bob Veale vs Chris Short | Sixth | 6½ out |
| » Lost to Phillies (58-52), 5-2 | Shibe Park (4-5) | 59-55 | |
| » Starters: Tommie Sisk vs Ray Herbert | Sixth | 6½ out |
| Tuesday, August 10 |
| » Lost to Giants (62-46), 4-3 | Candlestick Park (2-5) | 59-56 | Lost 2 |
| » Starters: Don Cardwell vs Juan Marichal | Sixth | 7½ out |
| Thursday, August 12 |
| » Lost to Giants (63-46), 4-3 | Candlestick Park (2-6) | 59-57 | Lost 3 |
| » Starters: Bob Friend vs Bob Shaw | Sixth | 8 out |
| » Defeated Giants (63-47), 5-2 | Candlestick Park (3-6) | 60-57 | |
| » Starters: Vern Law vs Gaylord Perry | Sixth | 8 out |
| Friday, August 13 |
| » Lost to Dodgers (68-48), 3-1 | Dodger Stadium (4-3) | 60-58 | |
| » Starters: Bob Veale vs Claude Osteen | Sixth | 9 out |
| Saturday, August 14 |
| » Lost to Dodgers (69-48), 1-0 | Dodger Stadium (4-4) | 60-59 | Lost 2 |
| » Starters: Don Cardwell vs Sandy Koufax | Sixth | 10 out |
| Sunday, August 15 |
| » Defeated Dodgers (69-49), 4-2 | Dodger Stadium (5-4) | 61-59 | |
| » Starters: Tommie Sisk vs Don Drysdale | Sixth | 9 out |
| Monday, August 16 |
| » Lost to Astros (49-69), 3-0 | Astrodome (1-6) | 61-60 | |
| » Starters: Bob Friend vs Robin Roberts | Sixth | 9 out |
| Tuesday, August 17 |
| » Defeated Astros (49-70), 8-6 | Astrodome (2-6) | 62-60 | |
| » Starters: Vern Law vs Turk Farrell | Sixth | 9 out |
| Future Pirate Alex Cole is born in Fayetteville, NC. |
| Wednesday, August 18 |
| » Defeated Astros (49-71), 8-7 | Astrodome (3-6) | 63-60 | Won 2 |
| » Starters: Bob Veale vs Don Nottebart | Sixth | 8½ out |
| Friday, August 20 |
| » Lost to Braves (70-50), 4-3 | Forbes Field (28-26) | 63-61 | |
| » Starters: Wade Blasingame vs Don Cardwell | Sixth | 9 out |
| Saturday, August 21 |
| » Defeated Braves (70-51), 3-0 | Forbes Field (29-26) | 64-61 | |
| » Starters: Denny Lemaster vs Bob Friend | Sixth | 8½ out |
| Former Pirate Bill Harris dies in Indian Trail, NC at the age of 66. |
| Sunday, August 22 |
| » Defeated Braves (70-52), 5-4 | Forbes Field (30-26) | 65-61 | Won 2 |
| » Starters: Tony Cloninger vs Bob Veale | Sixth | 7½ out |
| Monday, August 23 |
| » Defeated Giants (69-52), 6-2 | Forbes Field (31-26) | 66-61 | Won 3 |
| » Starters: Warren Spahn vs Vern Law | Sixth | 7½ out |
| Tuesday, August 24 |
| » Defeated Giants (69-53), 5-2 | Forbes Field (32-26) | 67-61 | Won 4 |
| » Starters: Bob Shaw vs Don Cardwell | Sixth | 6½ out |
| Wednesday, August 25 |
| » Tied Giants, 3-3 | Forbes Field (32-26) | 67-61 | |
| » Starters: Bobby Bolin vs Bob Friend | Sixth | 6 out |
| Thursday, August 26 |
| » Defeated Giants (69-54), 8-0 | Forbes Field (33-26) | 68-61 | Won 5 |
| » Starters: Ron Herbel vs Bob Veale | Fourth | 4½ out |
| » Defeated Giants (69-55), 6-5 | Forbes Field (34-26) | 69-61 | Won 6 |
| » Starters: Gaylord Perry vs Tommie Sisk | Fourth | 4½ out |
| Future Pirate Jeff Richardson is born in Grand Island, NE. |
| Friday, August 27 |
| » Defeated Astros (54-74), 10-9 | Forbes Field (35-26) | 70-61 | Won 7 |
| » Starters: Turk Farrell vs Vern Law | Fourth | 4½ out |
| Saturday, August 28 |
| » Lost to Astros (55-74), 9-6 | Forbes Field (35-27) | 70-62 | |
| » Starters: Larry Dierker vs Don Cardwell | Fifth | 5½ out |
| Sunday, August 29 |
| » Defeated Astros (55-75), 4-2 | Forbes Field (36-27) | 71-62 | |
| » Starters: Don Nottebart vs Bob Friend | Fifth | 4½ out |
| Former Pirate Paul Waner dies in Sarasota, FL at the age of 63. |
| Monday, August 30 |
| Former Pirate Frank Papish dies in Pueblo, CO at the age of 48. |
| Wednesday, September 1 |
| » Defeated Dodgers (75-58), 3-2 | Forbes Field (37-27) | 72-62 | Won 2 |
| » Starters: Sandy Koufax vs Tommie Sisk | Fifth | 2½ out |
| » Defeated Dodgers (75-59), 2-1 | Forbes Field (38-27) | 73-62 | Won 3 |
| » Starters: Don Drysdale vs Vern Law | Fifth | 2½ out |
| Thursday, September 2 |
| » Lost to Dodgers (76-59), 7-1 | Forbes Field (38-28) | 73-63 | |
| » Starters: Claude Osteen vs Bob Veale | Fifth | 3½ out |
| Friday, September 3 |
| » Lost to Braves (74-60), 4-3 | County Stadium (3-4) | 73-64 | Lost 2 |
| » Starters: Don Cardwell vs Ken Johnson | Fifth | 4½ out |
| Saturday, September 4 |
| » Lost to Braves (75-60), 8-3 | County Stadium (3-5) | 73-65 | Lost 3 |
| » Starters: Bob Friend vs Tony Cloninger | Fifth | 5½ out |
| Sunday, September 5 |
| » Defeated Braves (75-61), 2-1 | County Stadium (4-5) | 74-65 | |
| » Starters: Tommie Sisk vs Bob Sadowski | Fifth | 5½ out |
| Monday, September 6 |
| » Defeated Reds (77-60), 3-1 | Crosley Field (4-3) | 75-65 | Won 2 |
| » Starters: Bob Veale vs Joey Jay | Fourth | 4 out |
| » Defeated Reds (77-61), 4-2 | Crosley Field (5-3) | 76-65 | Won 3 |
| » Starters: Joe Gibbon vs Jim Maloney | Fourth | 4 out |
| Tuesday, September 7 |
| » Lost to Reds (78-61), 5-0 | Crosley Field (5-4) | 76-66 | |
| » Starters: Don Cardwell vs Sammy Ellis | Fifth | 4 out |
| » Major-league debuts: Luke Walker (Pirates) |
| Wednesday, September 8 |
| » Defeated Cardinals (70-71), 2-1 | Sportsman's Park III (4-5) | 77-66 | |
| » Starters: Bob Friend vs Ray Sadecki | Fourth | 4 out |
| Thursday, September 9 |
| » Major-league debuts: Byron Browne and Don Young (Cubs) |
| Friday, September 10 |
| » Defeated Reds (80-62), 7-0 | Forbes Field (39-28) | 78-66 | Won 2 |
| » Starters: Joey Jay vs Bob Veale | Fifth | 4½ out |
| » Major-league debuts: Bob Oliver (Pirates) |
| Saturday, September 11 |
| » Lost to Reds (81-62), 3-2 | Forbes Field (39-29) | 78-67 | |
| » Starters: Jim Maloney vs Tommie Sisk | Fifth | 5½ out |
| Monday, September 13 |
| » Defeated Reds (81-63), 8-4 | Forbes Field (40-29) | 79-67 | |
| » Starters: Sammy Ellis vs Vern Law | Fifth | 6½ out |
| Tuesday, September 14 |
| » Lost to Cardinals (71-73), 3-2 | Forbes Field (40-30) | 79-68 | |
| » Starters: Bob Gibson vs Bob Friend | Fourth | 7½ out |
| Wednesday, September 15 |
| » Lost to Cardinals (72-73), 7-3 | Forbes Field (40-31) | 79-69 | Lost 2 |
| » Starters: Ray Sadecki vs Bob Veale | Fifth | 8½ out |
| » Major-league debuts: George Spriggs (Pirates) |
| Thursday, September 16 |
| » Lost to Cardinals (73-73), 2-1 | Forbes Field (40-32) | 79-70 | Lost 3 |
| » Starters: Tracy Stallard vs Tommie Sisk | Fourth | 9½ out |
| Friday, September 17 |
| » Defeated Phillies (76-70), 4-0 | Forbes Field (41-32) | 80-70 | |
| » Starters: Ray Culp vs Don Cardwell | Fourth | 8½ out |
| Saturday, September 18 |
| » Defeated Phillies (76-71), 4-3 | Forbes Field (42-32) | 81-70 | Won 2 |
| » Starters: Jim Bunning vs Bob Friend | Fifth | 8½ out |
| Sunday, September 19 |
| » Defeated Phillies (76-72), 1-0 | Forbes Field (43-32) | 82-70 | Won 3 |
| » Starters: Chris Short vs Bob Veale | Fifth | 8½ out |
| Monday, September 20 |
| » Defeated Mets (48-104), 10-0 | Forbes Field (44-32) | 83-70 | Won 4 |
| » Starters: Jack Fisher vs Tommie Sisk | Fourth | 8½ out |
| Tuesday, September 21 |
| » Defeated Mets (48-105), 6-5 | Forbes Field (45-32) | 84-70 | Won 5 |
| » Starters: Al Jackson vs Don Cardwell | Fourth | 7½ out |
| Wednesday, September 22 |
| » Defeated Mets (48-106), 6-2 | Forbes Field (46-32) | 85-70 | Won 6 |
| » Starters: Tug McGraw vs Bob Friend | Fourth | 6½ out |
| Saturday, September 25 |
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