| Tuesday, February 9 |
| Future Oriole Doug Linton is born in Santa Ana, CA. |
| Wednesday, February 10 |
| Future Oriole Lenny Webster is born in New Orleans, LA. |
| Friday, March 12 |
| Future Oriole Steve Finley is born in Paducah, KY. |
| Sunday, March 14 |
| Future Oriole Kevin Brown is born in Milledgeville, GA. |
| Thursday, March 18 |
| Future Oriole Geronimo Berroa is born in Santo Domingo, D.R. |
| Saturday, March 20 |
| Future Oriole Chris Hoiles is born in Bowling Green, OH. |
| Tuesday, April 13 |
| » Lost to White Sox (1-0), 5-3 | Memorial Stadium (0-1) | 0-1 | |
| » Starters: Gary Peters vs Steve Barber | Third | 1½ out |
| » Major-league debuts: Davey Johnson (Orioles) |
| Wednesday, April 14 |
| » Defeated White Sox (1-1), 6-0 | Memorial Stadium (1-1) | 1-1 | |
| » Starters: Joe Horlen vs Milt Pappas | Third | 1 out |
| » Major-league debuts: Curt Blefary (Orioles) |
| Saturday, April 17 |
| » Lost to Red Sox (2-1), 12-9 | Fenway Park (0-1) | 1-2 | |
| » Starters: Robin Roberts vs Bill Monbouquette | Fourth | 1½ out |
| » Major-league debuts: Jim Palmer (Orioles) |
| Future Oriole Craig Worthington is born in Los Angeles, CA. |
| Sunday, April 18 |
| » Lost to Red Sox (3-1), 11-4 | Fenway Park (0-2) | 1-3 | Lost 2 |
| » Starters: Wally Bunker vs Earl Wilson | Sixth | 2½ out |
| » Major-league debuts: Darold Knowles (Orioles) |
| Monday, April 19 |
| » Lost to White Sox (4-3), 7-2 | Comiskey Park I (0-1) | 1-4 | Lost 3 |
| » Starters: Milt Pappas vs Tommy John | Seventh | 2½ out |
| Wednesday, April 21 |
| » Defeated Senators (3-5), 3-2 | Robert F. Kennedy Stadium (1-0) | 2-4 | |
| » Starters: Dave McNally vs Bennie Daniels | Eighth | 2½ out |
| Thursday, April 22 |
| » Defeated Senators (3-6), 18-4 | Robert F. Kennedy Stadium (2-0) | 3-4 | Won 2 |
| » Starters: Wally Bunker vs Phil Ortega | Fifth | 2½ out |
| Friday, April 23 |
| » Defeated Red Sox (4-3), 4-2 | Memorial Stadium (2-1) | 4-4 | Won 3 |
| » Starters: Jim Lonborg vs Robin Roberts | Sixth | 2½ out |
| » Major-league debuts: Jim Lonborg (Red Sox) |
| Saturday, April 24 |
| » Lost to Red Sox (5-3), 7-5 | Memorial Stadium (2-2) | 4-5 | |
| » Starters: Earl Wilson vs Milt Pappas | Seventh | 2½ out |
| Tuesday, April 27 |
| » Lost to Senators (4-8), 5-2 | Memorial Stadium (2-3) | 4-6 | Lost 2 |
| » Starters: Bennie Daniels vs Dave McNally | Seventh | 3½ out |
| Wednesday, April 28 |
| » Defeated Senators (4-9), 6-3 | Robert F. Kennedy Stadium (3-0) | 5-6 | |
| » Starters: Robin Roberts vs Pete Richert | Sixth | 3 out |
| Thursday, April 29 |
| » Defeated Senators (4-10), 5-4 | Memorial Stadium (3-3) | 6-6 | Won 2 |
| » Starters: Phil Ortega vs Wally Bunker | Fifth | 2½ out |
| Friday, April 30 |
| » Defeated Yankees (6-7), 10-4 | Yankee Stadium (1-0) | 7-6 | Won 3 |
| » Starters: Steve Barber vs Jim Bouton | Fourth | 2 out |
| Saturday, May 1 |
| » Lost to Yankees (7-7), 9-4 | Yankee Stadium (1-1) | 7-7 | |
| » Starters: Don Larsen vs Whitey Ford | Fourth | 2½ out |
| Sunday, May 2 |
| » Defeated Yankees (7-8), 4-2 | Yankee Stadium (2-1) | 8-7 | |
| » Starters: Dave McNally vs Mel Stottlemyre | Fourth | 1½ out |
| » Defeated Yankees (7-9), 5-0 | Yankee Stadium (3-1) | 9-7 | Won 2 |
| » Starters: Robin Roberts vs Al Downing | Fourth | 1½ out |
| Tuesday, May 4 |
| » Lost to Twins (10-5), 7-3 | Metropolitan Stadium (0-1) | 9-8 | |
| » Starters: Wally Bunker vs Mudcat Grant | Fifth | 2½ out |
| Wednesday, May 5 |
| » Lost to Twins (11-5), 9-2 | Metropolitan Stadium (0-2) | 9-9 | Lost 2 |
| » Starters: Steve Barber vs Camilo Pascual | Fifth | 4 out |
| Thursday, May 6 |
| » Defeated Twins (11-6), 5-1 | Metropolitan Stadium (1-2) | 10-9 | |
| » Starters: Robin Roberts vs Jim Kaat | Fifth | 3½ out |
| Saturday, May 8 |
| » Lost to Tigers (10-9), 4-3 | Memorial Stadium (3-4) | 10-10 | |
| » Starters: Hank Aguirre vs Dave McNally | Sixth | 4 out |
| Sunday, May 9 |
| » Defeated Tigers (10-10), 7-1 | Memorial Stadium (4-4) | 11-10 | |
| » Starters: Phil Regan vs Milt Pappas | Fifth | 2½ out |
| » Defeated Tigers (10-11), 5-4 | Memorial Stadium (5-4) | 12-10 | Won 2 |
| » Starters: Denny McLain vs Jim Palmer | Fifth | 2½ out |
| Monday, May 10 |
| » Lost to Tigers (11-11), 5-4 | Memorial Stadium (5-5) | 12-11 | |
| » Starters: Mickey Lolich vs Robin Roberts | Fifth | 3 out |
| Tuesday, May 11 |
| » Defeated Indians (11-9), 3-2 | Memorial Stadium (6-5) | 13-11 | |
| » Starters: Ralph Terry vs Steve Barber | Fifth | 3 out |
| Wednesday, May 12 |
| » Defeated Indians (11-10), 4-2 | Memorial Stadium (7-5) | 14-11 | Won 2 |
| » Starters: Luis Tiant vs Dave McNally | Fourth | 3 out |
| Thursday, May 13 |
| » Defeated Indians (11-11), 3-2 | Memorial Stadium (8-5) | 15-11 | Won 3 |
| » Starters: Jack Kralick vs Milt Pappas | Fourth | 2½ out |
| Friday, May 14 |
| » Lost to Yankees (11-16), 9-3 | Memorial Stadium (8-6) | 15-12 | |
| » Starters: Bill Stafford vs Robin Roberts | Fifth | 3½ out |
| Saturday, May 15 |
| » Lost to Yankees (12-16), 3-2 | Memorial Stadium (8-7) | 15-13 | Lost 2 |
| » Starters: Mel Stottlemyre vs Steve Barber | Fifth | 4½ out |
| Sunday, May 16 |
| » Defeated Yankees (12-17), 7-5 | Memorial Stadium (9-7) | 16-13 | |
| » Starters: Jim Bouton vs Dave McNally | Third | 5 out |
| Monday, May 17 |
| » Defeated Yankees (12-18), 9-2 | Memorial Stadium (10-7) | 17-13 | Won 2 |
| » Starters: Whitey Ford vs Milt Pappas | Third | 5 out |
| Tuesday, May 18 |
| » Lost to Indians (14-13), 1-0 | Cleveland Stadium (0-1) | 17-14 | |
| » Starters: Robin Roberts vs Jack Kralick | Third | 6 out |
| Wednesday, May 19 |
| » Lost to Indians (15-13), 2-0 | Cleveland Stadium (0-2) | 17-15 | Lost 2 |
| » Starters: Steve Barber vs Sam McDowell | Fifth | 6 out |
| Thursday, May 20 |
| » Lost to Indians (16-13), 5-2 | Cleveland Stadium (0-3) | 17-16 | Lost 3 |
| » Starters: Dave McNally vs Sonny Siebert | Fifth | 6½ out |
| Friday, May 21 |
| » Defeated Tigers (18-15), 5-2 | Tiger Stadium (1-0) | 18-16 | |
| » Starters: Milt Pappas vs Dave Wickersham | Fifth | 5½ out |
| Saturday, May 22 |
| » Lost to Tigers (19-15), 8-4 | Tiger Stadium (1-1) | 18-17 | |
| » Starters: Robin Roberts vs Joe Sparma | Sixth | 5½ out |
| Sunday, May 23 |
| » Defeated Tigers (19-16), 7-3 | Tiger Stadium (2-1) | 19-17 | |
| » Starters: Steve Barber vs Hank Aguirre | Third | 5 out |
| » Defeated Tigers (19-17), 8-3 | Tiger Stadium (3-1) | 20-17 | Won 2 |
| » Starters: Dave McNally vs Jack Hamilton | Third | 5 out |
| Monday, May 24 |
| » Defeated Senators (15-24), 2-1 | Robert F. Kennedy Stadium (4-0) | 21-17 | Won 3 |
| » Starters: Jim Palmer vs Bennie Daniels | Third | 4 out |
| Tuesday, May 25 |
| » Defeated Athletics (9-25), 6-3 | Memorial Stadium (11-7) | 22-17 | Won 4 |
| » Starters: John O'Donoghue vs Milt Pappas | Third | 3 out |
| Wednesday, May 26 |
| » Lost to Athletics (10-25), 6-3 | Memorial Stadium (11-8) | 22-18 | |
| » Starters: Diego Segui vs Robin Roberts | Fourth | 3 out |
| Friday, May 28 |
| » Lost to Angels (22-21), 3-1 | Memorial Stadium (11-9) | 22-19 | Lost 2 |
| » Starters: George Brunet vs Dave McNally | Fourth | 3½ out |
| » Defeated Angels (22-22), 3-0 | Memorial Stadium (12-9) | 23-19 | |
| » Starters: Aubrey Gatewood vs Steve Barber | Fourth | 3½ out |
| Saturday, May 29 |
| » Lost to Angels (23-22), 3-1 | Memorial Stadium (12-10) | 23-20 | |
| » Starters: Fred Newman vs Milt Pappas | Fourth | 4½ out |
| Sunday, May 30 |
| » Defeated Angels (23-23), 4-3 | Memorial Stadium (13-10) | 24-20 | |
| » Starters: Marcelino Lopez vs Wally Bunker | Fourth | 4 out |
| Monday, May 31 |
| » Lost to Twins (27-14), 6-0 | Memorial Stadium (13-11) | 24-21 | |
| » Starters: Jim Kaat vs Robin Roberts | Fourth | 4 out |
| » Defeated Twins (27-15), 5-4 | Memorial Stadium (14-11) | 25-21 | |
| » Starters: Dick Stigman vs Jim Palmer | Fourth | 4 out |
| Wednesday, June 2 |
| » Defeated Athletics (10-30), 6-4 | Municipal Stadium (1-0) | 26-21 | Won 2 |
| » Starters: Steve Barber vs Fred Talbot | Fourth | 4 out |
| Friday, June 4 |
| » Lost to Angels (26-26), 4-3 | Dodger Stadium (0-1) | 26-22 | |
| » Starters: Milt Pappas vs Marcelino Lopez | Fourth | 5½ out |
| Saturday, June 5 |
| » Defeated Angels (26-27), 7-0 | Dodger Stadium (1-1) | 27-22 | |
| » Starters: Wally Bunker vs George Brunet | Third | 5 out |
| Sunday, June 6 |
| » Lost to Angels (27-27), 3-0 | Dodger Stadium (1-2) | 27-23 | |
| » Starters: Jim Palmer vs Rudy May | Fourth | 6 out |
| Tuesday, June 8 |
| » Lost to Senators (23-30), 2-0 | Robert F. Kennedy Stadium (4-1) | 27-24 | Lost 2 |
| » Starters: Steve Barber vs Pete Richert | Fifth | 6½ out |
| Wednesday, June 9 |
| » Lost to Senators (24-30), 3-2 | Memorial Stadium (14-12) | 27-25 | Lost 3 |
| » Starters: Howie Koplitz vs Milt Pappas | Fifth | 6½ out |
| Thursday, June 10 |
| » Defeated Senators (24-31), 5-1 | Robert F. Kennedy Stadium (5-1) | 28-25 | |
| » Starters: Wally Bunker vs Buster Narum | Fifth | 5½ out |
| Friday, June 11 |
| » Defeated Red Sox (24-29), 5-4 | Fenway Park (1-2) | 29-25 | Won 2 |
| » Starters: Robin Roberts vs Dennis Bennett | Fourth | 6 out |
| Saturday, June 12 |
| » Defeated Red Sox (24-30), 5-4 | Fenway Park (2-2) | 30-25 | Won 3 |
| » Starters: Jim Palmer vs Jim Lonborg | Third | 5 out |
| Sunday, June 13 |
| » Defeated Red Sox (24-31), 1-0 | Fenway Park (3-2) | 31-25 | Won 4 |
| » Starters: Milt Pappas vs Bill Monbouquette | Third | 4 out |
| Tuesday, June 15 |
| » Defeated Yankees (26-31), 2-1 | Yankee Stadium (4-1) | 32-25 | Won 5 |
| » Starters: Wally Bunker vs Mel Stottlemyre | Third | 4 out |
| Wednesday, June 16 |
| » Defeated Yankees (26-32), 5-1 | Yankee Stadium (5-1) | 33-25 | Won 6 |
| » Starters: Dave McNally vs Al Downing | Third | 3 out |
| Thursday, June 17 |
| » Defeated Yankees (26-33), 2-1 | Yankee Stadium (6-1) | 34-25 | Won 7 |
| » Starters: Robin Roberts vs Jim Bouton | Third | 3 out |
| Friday, June 18 |
| » Lost to Senators (26-37), 2-0 | Memorial Stadium (14-13) | 34-26 | |
| » Starters: Pete Richert vs Jim Palmer | Fifth | 3 out |
| Saturday, June 19 |
| » Defeated Senators (26-38), 3-1 | Memorial Stadium (15-13) | 35-26 | |
| » Starters: Buster Narum vs Milt Pappas | Fifth | 2 out |
| Sunday, June 20 |
| » Defeated Senators (26-39), 13-2 | Memorial Stadium (16-13) | 36-26 | Won 2 |
| » Starters: Howie Koplitz vs Wally Bunker | Fourth | 2½ out |
| Tuesday, June 22 |
| » Defeated Red Sox (25-37), 4-1 | Memorial Stadium (17-13) | 37-26 | Won 3 |
| » Starters: Dave Morehead vs John Miller | Third | 2 out |
| » Lost to Red Sox (26-37), 4-2 | Memorial Stadium (17-14) | 37-27 | |
| » Starters: Earl Wilson vs Robin Roberts | Third | 2 out |
| Wednesday, June 23 |
| » Defeated Red Sox (26-38), 6-4 | Memorial Stadium (18-14) | 38-27 | |
| » Starters: Jim Lonborg vs Steve Barber | Fourth | 2 out |
| Thursday, June 24 |
| » Defeated Red Sox (26-39), 4-1 | Memorial Stadium (19-14) | 39-27 | Won 2 |
| » Starters: Bill Monbouquette vs Milt Pappas | Third | 1 out |
| Friday, June 25 |
| » Lost to White Sox (39-25), 6-0 | Comiskey Park I (0-2) | 39-28 | |
| » Starters: Wally Bunker vs Joe Horlen | Third | 2 out |
| Saturday, June 26 |
| » Defeated White Sox (39-26), 2-0 | Comiskey Park I (1-2) | 40-28 | |
| » Starters: Dave McNally vs Gary Peters | Third | 1 out |
| Sunday, June 27 |
| » Lost to White Sox (40-26), 6-2 | Comiskey Park I (1-3) | 40-29 | |
| » Starters: John Miller vs Tommy John | Third | 3 out |
| » Lost to White Sox (41-26), 4-0 | Comiskey Park I (1-4) | 40-30 | Lost 2 |
| » Starters: Steve Barber vs Bruce Howard | Third | 3 out |
| Monday, June 28 |
| » Lost to Tigers (39-30), 4-3 | Memorial Stadium (19-15) | 40-31 | Lost 3 |
| » Starters: Denny McLain vs Wally Bunker | Fourth | 3½ out |
| Tuesday, June 29 |
| » Defeated Tigers (39-31), 3-2 | Memorial Stadium (20-15) | 41-31 | |
| » Starters: Dave Wickersham vs Milt Pappas | Fourth | 3½ out |
| Wednesday, June 30 |
| » Lost to Yankees (36-38), 5-4 | Memorial Stadium (20-16) | 41-32 | |
| » Starters: Jim Bouton vs Dave McNally | Fourth | 3½ out |
| Thursday, July 1 |
| » Defeated Yankees (36-39), 4-3 | Memorial Stadium (21-16) | 42-32 | |
| » Starters: Whitey Ford vs Steve Barber | Fourth | 3½ out |
| Friday, July 2 |
| » Lost to Indians (45-27), 8-0 | Memorial Stadium (21-17) | 42-33 | |
| » Starters: Lee Stange vs John Miller | Fourth | 4½ out |
| Saturday, July 3 |
| » Defeated Indians (45-28), 8-4 | Memorial Stadium (22-17) | 43-33 | |
| » Starters: Luis Tiant vs Wally Bunker | Third | 3½ out |
| Sunday, July 4 |
| » Lost to Indians (46-28), 4-2 | Cleveland Stadium (0-4) | 43-34 | |
| » Starters: Milt Pappas vs Ralph Terry | Third | 4½ out |
| Monday, July 5 |
| » Defeated Athletics (22-49), 7-4 | Municipal Stadium (2-0) | 44-34 | |
| » Starters: Dave McNally vs Rollie Sheldon | Fourth | 5 out |
| Tuesday, July 6 |
| » Defeated Athletics (22-50), 4-1 | Municipal Stadium (3-0) | 45-34 | Won 2 |
| » Starters: Steve Barber vs Catfish Hunter | Fourth | 5 out |
| Wednesday, July 7 |
| » Defeated Athletics (22-51), 1-0 | Municipal Stadium (4-0) | 46-34 | Won 3 |
| » Starters: John Miller vs John O'Donoghue | Third | 5 out |
| Thursday, July 8 |
| » Defeated Athletics (22-52), 10-6 | Municipal Stadium (5-0) | 47-34 | Won 4 |
| » Starters: Wally Bunker vs Diego Segui | Third | 4½ out |
| Future Oriole Jerome Walton is born in Newnan, GA. |
| Friday, July 9 |
| » Defeated White Sox (45-34), 1-0 | Memorial Stadium (23-17) | 48-34 | Won 5 |
| » Starters: Bruce Howard vs Milt Pappas | Third | 4½ out |
| Saturday, July 10 |
| » Lost to White Sox (46-34), 6-4 | Memorial Stadium (23-18) | 48-35 | |
| » Starters: Gary Peters vs Robin Roberts | Third | 4½ out |
| » Defeated White Sox (46-35), 5-3 | Memorial Stadium (24-18) | 49-35 | |
| » Starters: Joe Horlen vs Dave McNally | Third | 4½ out |
| Future Oriole Buddy Groom is born in Dallas, TX. |
| Thursday, July 15 |
| » Lost to Tigers (47-36), 5-4 | Tiger Stadium (3-2) | 49-36 | |
| » Starters: Steve Barber vs Mickey Lolich | Fourth | 5½ out |
| Friday, July 16 |
| » Defeated Tigers (47-37), 2-1 | Tiger Stadium (4-2) | 50-36 | |
| » Starters: Milt Pappas vs Denny McLain | Fourth | 4½ out |
| Sunday, July 18 |
| » Defeated Tigers (47-38), 4-1 | Tiger Stadium (5-2) | 51-36 | Won 2 |
| » Starters: Wally Bunker vs Hank Aguirre | Second | 3½ out |
| Monday, July 19 |
| » Lost to Indians (52-36), 5-0 | Cleveland Stadium (0-5) | 51-37 | |
| » Starters: Steve Barber vs Lee Stange | Third | 4½ out |
| Tuesday, July 20 |
| » Defeated Indians (52-37), 6-1 | Cleveland Stadium (1-5) | 52-37 | |
| » Starters: Dave McNally vs Ralph Terry | Second | 3½ out |
| Wednesday, July 21 |
| » Defeated Athletics (28-57), 1-0 | Memorial Stadium (25-18) | 53-37 | Won 2 |
| » Starters: John O'Donoghue vs Milt Pappas | Second | 3½ out |
| » Defeated Athletics (28-58), 9-2 | Memorial Stadium (26-18) | 54-37 | Won 3 |
| » Starters: Diego Segui vs John Miller | Second | 3½ out |
| Future Oriole Mike Bordick is born in Marquette, MI. |
| Thursday, July 22 |
| » Lost to Athletics (29-58), 9-2 | Memorial Stadium (26-19) | 54-38 | |
| » Starters: Fred Talbot vs Wally Bunker | Second | 4½ out |
| Friday, July 23 |
| » Defeated Twins (59-35), 3-2 | Memorial Stadium (27-19) | 55-38 | |
| » Starters: Jim Perry vs Steve Barber | Second | 3½ out |
| Saturday, July 24 |
| » Defeated Twins (59-36), 3-1 | Memorial Stadium (28-19) | 56-38 | Won 2 |
| » Starters: Camilo Pascual vs Dave McNally | Second | 2½ out |
| Sunday, July 25 |
| » Lost to Twins (60-36), 8-5 | Memorial Stadium (28-20) | 56-39 | |
| » Starters: Jim Kaat vs John Miller | Second | 3½ out |
| Monday, July 26 |
| » Lost to Twins (61-36), 8-2 | Memorial Stadium (28-21) | 56-40 | Lost 2 |
| » Starters: Mudcat Grant vs Milt Pappas | Second | 4½ out |
| Tuesday, July 27 |
| » Defeated Angels (46-53), 3-2 | Memorial Stadium (29-21) | 57-40 | |
| » Starters: Rudy May vs Wally Bunker | Second | 4 out |
| Wednesday, July 28 |
| » Defeated Angels (46-54), 5-1 | Memorial Stadium (30-21) | 58-40 | Won 2 |
| » Starters: Fred Newman vs Steve Barber | Second | 4 out |
| Friday, July 30 |
| » Lost to Twins (64-37), 3-2 | Metropolitan Stadium (1-3) | 58-41 | |
| » Starters: Dave McNally vs Mudcat Grant | Second | 5 out |
| Saturday, July 31 |
| » Lost to Twins (65-37), 2-1 | Metropolitan Stadium (1-4) | 58-42 | Lost 2 |
| » Starters: John Miller vs Jim Perry | Second | 6 out |
| Sunday, August 1 |
| » Defeated Twins (65-38), 7-6 | Metropolitan Stadium (2-4) | 59-42 | |
| » Starters: Milt Pappas vs Jim Kaat | Second | 5 out |
| Monday, August 2 |
| » Lost to Twins (66-38), 6-5 | Metropolitan Stadium (2-5) | 59-43 | |
| » Starters: Steve Barber vs Jim Merritt | Second | 6 out |
| » Major-league debuts: Jim Merritt (Twins) |
| Tuesday, August 3 |
| » Defeated Angels (48-56), 5-2 | Dodger Stadium (2-2) | 60-43 | |
| » Starters: Wally Bunker vs Fred Newman | Second | 5½ out |
| Wednesday, August 4 |
| » Defeated Angels (48-57), 6-5 | Dodger Stadium (3-2) | 61-43 | Won 2 |
| » Starters: John Miller vs Dean Chance | Second | 5 out |
| » Defeated Angels (48-58), 8-0 | Dodger Stadium (4-2) | 62-43 | Won 3 |
| » Starters: Dave McNally vs Rudy May | Second | 5 out |
| Friday, August 6 |
| » Lost to Athletics (36-67), 9-4 | Municipal Stadium (5-1) | 62-44 | |
| » Starters: Milt Pappas vs Rollie Sheldon | Second | 6½ out |
| Saturday, August 7 |
| » Lost to Athletics (37-67), 7-4 | Municipal Stadium (5-2) | 62-45 | Lost 2 |
| » Starters: Steve Barber vs Catfish Hunter | Second | 7½ out |
| » Major-league debuts: Mark Belanger (Orioles) |
| Sunday, August 8 |
| » Defeated Athletics (37-68), 9-5 | Municipal Stadium (6-2) | 63-45 | |
| » Starters: Wally Bunker vs Diego Segui | Second | 8 out |
| » Lost to Athletics (38-68), 4-3 | Municipal Stadium (6-3) | 63-46 | |
| » Starters: Dave McNally vs John O'Donoghue | Second | 8 out |
| Tuesday, August 10 |
| » Lost to Red Sox (41-68), 15-5 | Fenway Park (3-3) | 63-47 | Lost 2 |
| » Starters: Milt Pappas vs Jim Lonborg | Second | 8½ out |
| » Defeated Red Sox (41-69), 12-4 | Fenway Park (4-3) | 64-47 | |
| » Starters: John Miller vs Bill Monbouquette | Second | 8½ out |
| Wednesday, August 11 |
| » Lost to Red Sox (42-69), 8-3 | Fenway Park (4-4) | 64-48 | |
| » Starters: Steve Barber vs Earl Wilson | Second | 8½ out |
| Future Oriole John Mitchell is born in Dickson, TN. |
| Thursday, August 12 |
| » Defeated Red Sox (42-70), 5-3 | Fenway Park (5-4) | 65-48 | |
| » Starters: Dave McNally vs Dave Morehead | Second | 8½ out |
| Friday, August 13 |
| » Lost to Senators (50-66), 4-2 | Memorial Stadium (30-22) | 65-49 | |
| » Starters: Phil Ortega vs Wally Bunker | Second | 8½ out |
| Saturday, August 14 |
| » Lost to Senators (51-66), 8-5 | Memorial Stadium (30-23) | 65-50 | Lost 2 |
| » Starters: Frank Kreutzer vs Milt Pappas | Third | 8½ out |
| Sunday, August 15 |
| » Lost to Senators (52-66), 4-2 | Memorial Stadium (30-24) | 65-51 | Lost 3 |
| » Starters: Pete Richert vs John Miller | Third | 9 out |
| Tuesday, August 17 |
| » Defeated Red Sox (43-74), 3-1 | Memorial Stadium (31-24) | 66-51 | |
| » Starters: Dave Morehead vs Steve Barber | Third | 8 out |
| Wednesday, August 18 |
| » Defeated Red Sox (43-75), 3-2 | Memorial Stadium (32-24) | 67-51 | Won 2 |
| » Starters: Dennis Bennett vs Dave McNally | Third | 7½ out |
| Thursday, August 19 |
| » Lost to Red Sox (44-75), 11-3 | Memorial Stadium (32-25) | 67-52 | |
| » Starters: Jim Lonborg vs Wally Bunker | Third | 9 out |
| Friday, August 20 |
| » Lost to Yankees (63-61), 1-0 | Memorial Stadium (32-26) | 67-53 | Lost 2 |
| » Starters: Jack Cullen vs Milt Pappas | Fourth | 9½ out |
| Monday, August 23 |
| » Defeated White Sox (71-52), 2-1 | Comiskey Park I (2-4) | 68-53 | |
| » Starters: Steve Barber vs Juan Pizarro | Fourth | 9½ out |
| Tuesday, August 24 |
| » Lost to White Sox (72-52), 6-5 | Comiskey Park I (2-5) | 68-54 | |
| » Starters: Dave McNally vs Bruce Howard | Fourth | 9½ out |
| Wednesday, August 25 |
| » Defeated White Sox (72-53), 2-1 | Comiskey Park I (3-5) | 69-54 | |
| » Starters: Milt Pappas vs Gary Peters | Fourth | 9½ out |
| Thursday, August 26 |
| » Defeated White Sox (72-54), 8-1 | Comiskey Park I (4-5) | 70-54 | Won 2 |
| » Starters: John Miller vs Tommy John | Third | 9½ out |
| Friday, August 27 |
| » Lost to Senators (56-73), 2-1 | Robert F. Kennedy Stadium (5-2) | 70-55 | |
| » Starters: Steve Barber vs Frank Kreutzer | Third | 10½ out |
| Saturday, August 28 |
| » Lost to Senators (57-73), 5-4 | Robert F. Kennedy Stadium (5-3) | 70-56 | Lost 2 |
| » Starters: Dave McNally vs Jim Duckworth | Third | 10½ out |
| Sunday, August 29 |
| » Lost to Senators (58-73), 5-4 | Robert F. Kennedy Stadium (5-4) | 70-57 | Lost 3 |
| » Starters: Milt Pappas vs Buster Narum | Fifth | 10½ out |
| Tuesday, August 31 |
| » Defeated White Sox (76-56), 4-0 | Memorial Stadium (33-26) | 71-57 | |
| » Starters: Joe Horlen vs John Miller | Third | 9½ out |
| » Defeated White Sox (76-57), 7-2 | Memorial Stadium (34-26) | 72-57 | Won 2 |
| » Starters: John Buzhardt vs Steve Barber | Third | 9½ out |
| Thursday, September 2 |
| » Lost to White Sox (77-57), 5-3 | Memorial Stadium (34-27) | 72-58 | |
| » Starters: Tommy John vs Dave McNally | Fifth | 10½ out |
| » Lost to White Sox (78-57), 9-3 | Memorial Stadium (34-28) | 72-59 | Lost 2 |
| » Starters: Juan Pizarro vs Milt Pappas | Fifth | 10½ out |
| Friday, September 3 |
| » Defeated Indians (74-60), 5-3 | Memorial Stadium (35-28) | 73-59 | |
| » Starters: Steve Hargan vs Wally Bunker | Fourth | 10½ out |
| Saturday, September 4 |
| » Defeated Indians (74-61), 1-0 | Memorial Stadium (36-28) | 74-59 | Won 2 |
| » Starters: Sam McDowell vs Steve Barber | Third | 9½ out |
| Sunday, September 5 |
| » Defeated Indians (74-62), 9-5 | Memorial Stadium (37-28) | 75-59 | Won 3 |
| » Starters: Lee Stange vs John Miller | Third | 8½ out |
| Monday, September 6 |
| » Defeated Yankees (68-72), 2-1 | Yankee Stadium (7-1) | 76-59 | Won 4 |
| » Starters: Milt Pappas vs Whitey Ford | Third | 7½ out |
| » Defeated Yankees (68-73), 6-2 | Yankee Stadium (8-1) | 77-59 | Won 5 |
| » Starters: Frank Bertaina vs Bill Stafford | Third | 7½ out |
| Tuesday, September 7 |
| » Defeated Yankees (68-74), 4-2 | Yankee Stadium (9-1) | 78-59 | Won 6 |
| » Starters: Dave McNally vs Al Downing | Third | 6½ out |
| » Defeated Yankees (68-75), 9-5 | Yankee Stadium (10-1) | 79-59 | Won 7 |
| » Starters: Wally Bunker vs Jack Cullen | Third | 6½ out |
| » Major-league debuts: Mike Jurewicz and Roy White (Yankees) |
| Wednesday, September 8 |
| » Defeated Tigers (77-64), 2-0 | Tiger Stadium (6-2) | 80-59 | Won 8 |
| » Starters: Steve Barber vs Hank Aguirre | Third | 7 out |
| » Lost to Tigers (78-64), 5-0 | Tiger Stadium (6-3) | 80-60 | |
| » Starters: Darold Knowles vs Dave Wickersham | Third | 7 out |
| » Major-league debuts: Ed Barnowski (Orioles) |
| Thursday, September 9 |
| Future Oriole Todd Zeile is born in Van Nuys, CA. |
| Friday, September 10 |
| » Defeated Athletics (51-90), 5-2 | Memorial Stadium (38-28) | 81-60 | |
| » Starters: Fred Talbot vs Milt Pappas | Second | 8 out |
| » Lost to Athletics (52-90), 10-5 | Memorial Stadium (38-29) | 81-61 | |
| » Starters: Catfish Hunter vs John Miller | Second | 8 out |
| Saturday, September 11 |
| » Lost to Athletics (53-90), 3-2 | Memorial Stadium (38-30) | 81-62 | Lost 2 |
| » Starters: Rollie Sheldon vs Wally Bunker | Third | 9 out |
| Tuesday, September 14 |
| » Defeated Tigers (80-65), 5-3 | Memorial Stadium (39-30) | 82-62 | |
| » Starters: Hank Aguirre vs Steve Barber | Second | 10 out |
| » Lost to Tigers (81-65), 7-1 | Memorial Stadium (39-31) | 82-63 | |
| » Starters: Dave Wickersham vs Milt Pappas | Second | 10 out |
| Wednesday, September 15 |
| » Defeated Tigers (81-66), 3-2 | Memorial Stadium (40-31) | 83-63 | |
| » Starters: Denny McLain vs Dave McNally | Second | 10 out |
| Thursday, September 16 |
| » Major-league debuts: Bill Davis (Indians) |
| Friday, September 17 |
| » Lost to Angels (70-80), 2-1 | Dodger Stadium (4-3) | 83-64 | |
| » Starters: Wally Bunker vs Dean Chance | Third | 10 out |
| Monday, September 20 |
| » Defeated Angels (70-81), 4-2 | Dodger Stadium (5-3) | 84-64 | |
| » Starters: Steve Barber vs Jim McGlothlin | Third | 10 out |
| » Major-league debuts: Jim McGlothin (Angels) |
| Tuesday, September 21 |
| » Defeated Twins (96-57), 6-4 | Metropolitan Stadium (3-5) | 85-64 | Won 2 |
| » Starters: Milt Pappas vs Camilo Pascual | Second | 9 out |
| Wednesday, September 22 |
| » Defeated Twins (96-58), 5-2 | Metropolitan Stadium (4-5) | 86-64 | Won 3 |
| » Starters: Dave McNally vs Jim Kaat | Second | 8 out |
| » Major-league debuts: Pete Cimino (Twins) |
| Friday, September 24 |
| » Defeated Angels (73-82), 10-6 | Memorial Stadium (41-31) | 87-64 | Won 4 |
| » Starters: Jack Sanford vs Wally Bunker | Second | 7½ out |
| Saturday, September 25 |
| » Defeated Angels (73-83), 2-1 | Memorial Stadium (42-31) | 88-64 | Won 5 |
| » Starters: Fred Newman vs Steve Barber | Second | 7½ out |
| » Defeated Angels (73-84), 2-0 | Memorial Stadium (43-31) | 89-64 | Won 6 |
| » Starters: Jim McGlothlin vs Milt Pappas | Second | 7½ out |
| Sunday, September 26 |
| » Defeated Angels (73-85), 2-1 | Memorial Stadium (44-31) | 90-64 | Won 7 |
| » Starters: George Brunet vs Dave McNally | Second | 7½ out |
| Monday, September 27 |
| » Defeated Athletics (58-98), 6-4 | Memorial Stadium (45-31) | 91-64 | Won 8 |
| » Starters: Fred Talbot vs John Miller | Second | 7 out |
| Tuesday, September 28 |
| » Defeated Twins (99-59), 4-2 | Memorial Stadium (46-31) | 92-64 | Won 9 |
| » Starters: Jim Perry vs Wally Bunker | Second | 6 out |
| Wednesday, September 29 |
| » Lost to Twins (100-59), 3-2 | Memorial Stadium (46-32) | 92-65 | |
