| Sunday, January 3 |
| Future Giant Mark Dewey is born in Grand Rapids, MI. |
| Thursday, January 7 |
| Former Giant George Smith dies in Greenwich, CT at the age of 73. |
| Wednesday, January 20 |
| Future Giant Brad Brink is born in Roseville, CA. |
| Saturday, February 13 |
| Future Giant Craig Colbert is born in Iowa City, IA. |
| Saturday, February 20 |
| Future Giant Paul Faries is born in Berkeley, CA. Future Giant Tony Menendez is born in Havana, Cuba. |
| Monday, March 22 |
| Future Giant Glenallen Hill is born in Santa Cruz, CA. |
| Monday, April 12 |
| » Lost to Pirates (1-0), 1-0 | Forbes Field (0-1) | 0-1 | |
| » Starters: Juan Marichal vs Bob Veale | Third | 1 out |
| Tuesday, April 13 |
| » Lost to Pirates (2-0), 5-2 | Forbes Field (0-2) | 0-2 | Lost 2 |
| » Starters: Jack Sanford vs Bob Friend | Fifth | 2 out |
| Wednesday, April 14 |
| » Defeated Phillies (1-1), 5-2 | Shibe Park (1-0) | 1-2 | |
| » Starters: Gaylord Perry vs Jim Bunning | Fourth | 1½ out |
| Saturday, April 17 |
| » Defeated Mets (1-3), 4-0 | Shea Stadium (1-0) | 2-2 | Won 2 |
| » Starters: Juan Marichal vs Tom Parsons | Third | 1 out |
| Sunday, April 18 |
| » Defeated Mets (1-4), 4-1 | Shea Stadium (2-0) | 3-2 | Won 3 |
| » Starters: Jack Sanford vs Al Jackson | Fifth | 1 out |
| » Lost to Mets (2-4), 7-1 | Shea Stadium (2-1) | 3-3 | |
| » Starters: Gaylord Perry vs Gary Kroll | Fifth | 1 out |
| » Major-league debuts: Tug McGraw (Mets) |
| Tuesday, April 20 |
| » Lost to Pirates (5-2), 3-1 | Candlestick Park (0-1) | 3-4 | Lost 2 |
| » Starters: Bob Friend vs Bobby Bolin | Fifth | 2 out |
| » Major-league debuts: Bob Schroder (Giants) |
| Wednesday, April 21 |
| » Defeated Pirates (5-3), 3-2 | Candlestick Park (1-1) | 4-4 | |
| » Starters: Joe Gibbon vs Juan Marichal | Fifth | 1½ out |
| Friday, April 23 |
| » Lost to Mets (4-6), 9-8 | Candlestick Park (1-2) | 4-5 | |
| » Starters: Gary Kroll vs Gaylord Perry | Fifth | 2½ out |
| » Major-league debuts: Ken Henderson (Giants) |
| Saturday, April 24 |
| » Lost to Mets (5-6), 7-6 | Candlestick Park (1-3) | 4-6 | Lost 2 |
| » Starters: Tom Parsons vs Jack Sanford | Seventh | 3½ out |
| Sunday, April 25 |
| » Defeated Mets (5-7), 5-0 | Candlestick Park (2-3) | 5-6 | |
| » Starters: Al Jackson vs Juan Marichal | Eighth | 3 out |
| » Lost to Mets (6-7), 4-3 | Candlestick Park (2-4) | 5-7 | |
| » Starters: Warren Spahn vs Bobby Bolin | Eighth | 3 out |
| Tuesday, April 27 |
| » Defeated Phillies (6-6), 14-13 | Candlestick Park (3-4) | 6-7 | |
| » Starters: Jim Bunning vs Gaylord Perry | Sixth | 2½ out |
| Wednesday, April 28 |
| » Defeated Phillies (6-7), 9-3 | Candlestick Park (4-4) | 7-7 | Won 2 |
| » Starters: Ray Culp vs Jack Sanford | Fifth | 2 out |
| Thursday, April 29 |
| » Lost to Dodgers (9-5), 2-1 | Dodger Stadium (0-1) | 7-8 | |
| » Starters: Juan Marichal vs Don Drysdale | Fifth | 2½ out |
| Friday, April 30 |
| » Lost to Dodgers (10-5), 6-3 | Dodger Stadium (0-2) | 7-9 | Lost 2 |
| » Starters: Bob Hendley vs Sandy Koufax | Sixth | 3½ out |
| Saturday, May 1 |
| » Lost to Dodgers (11-5), 4-2 | Dodger Stadium (0-3) | 7-10 | Lost 3 |
| » Starters: Gaylord Perry vs Johnny Podres | Seventh | 4½ out |
| Sunday, May 2 |
| » Defeated Dodgers (11-6), 4-2 | Dodger Stadium (1-3) | 8-10 | |
| » Starters: Jack Sanford vs Claude Osteen | Seventh | 4½ out |
| Monday, May 3 |
| » Lost to Cardinals (9-8), 3-1 | Sportsman's Park III (0-1) | 8-11 | |
| » Starters: Ron Herbel vs Curt Simmons | Eighth | 5 out |
| Tuesday, May 4 |
| » Defeated Cardinals (9-9), 9-2 | Sportsman's Park III (1-1) | 9-11 | |
| » Starters: Juan Marichal vs Ray Sadecki | Sixth | 4 out |
| Wednesday, May 5 |
| » Defeated Cardinals (9-10), 10-5 | Sportsman's Park III (2-1) | 10-11 | Won 2 |
| » Starters: Bob Hendley vs Tracy Stallard | Sixth | 4 out |
| Friday, May 7 |
| » Lost to Dodgers (15-6), 4-3 | Candlestick Park (4-5) | 10-12 | |
| » Starters: Claude Osteen vs Jack Sanford | Sixth | 5½ out |
| Saturday, May 8 |
| » Lost to Dodgers (16-6), 9-0 | Candlestick Park (4-6) | 10-13 | Lost 2 |
| » Starters: Don Drysdale vs Ron Herbel | Sixth | 6½ out |
| Sunday, May 9 |
| » Defeated Dodgers (16-7), 6-3 | Candlestick Park (5-6) | 11-13 | |
| » Starters: Sandy Koufax vs Gaylord Perry | Seventh | 5½ out |
| Tuesday, May 11 |
| » Defeated Cubs (11-13), 3-0 | Candlestick Park (6-6) | 12-13 | Won 2 |
| » Starters: Larry Jackson vs Ron Herbel | Fifth | 5 out |
| Wednesday, May 12 |
| » Lost to Cubs (12-13), 7-3 | Candlestick Park (6-7) | 12-14 | |
| » Starters: Cal Koonce vs Juan Marichal | Sixth | 6 out |
| Future Giant Angel Escobar is born in LaSabana, Venezuela. |
| Thursday, May 13 |
| » Defeated Cubs (12-14), 6-3 | Candlestick Park (7-7) | 13-14 | |
| » Starters: Ernie Broglio vs Jack Sanford | Sixth | 6 out |
| Friday, May 14 |
| » Defeated Astros (16-14), 2-1 | Candlestick Park (8-7) | 14-14 | Won 2 |
| » Starters: Ken Johnson vs Gaylord Perry | Sixth | 5 out |
| Saturday, May 15 |
| » Defeated Astros (16-15), 8-2 | Candlestick Park (9-7) | 15-14 | Won 3 |
| » Starters: Larry Dierker vs Ron Herbel | Fourth | 5 out |
| Sunday, May 16 |
| » Defeated Astros (16-16), 10-5 | Candlestick Park (10-7) | 16-14 | Won 4 |
| » Starters: Dave Giusti vs Juan Marichal | Third | 4 out |
| » Defeated Astros (16-17), 4-3 | Candlestick Park (11-7) | 17-14 | Won 5 |
| » Starters: Don Nottebart vs Bob Shaw | Third | 4 out |
| Monday, May 17 |
| Former Giant Bill Bartley dies in Cincinnati, OH at the age of 81. |
| Tuesday, May 18 |
| » Lost to Cubs (15-16), 7-6 | Wrigley Field (0-1) | 17-15 | |
| » Starters: Jack Sanford vs Ernie Broglio | Third | 4½ out |
| Wednesday, May 19 |
| » Lost to Cubs (16-16), 2-1 | Wrigley Field (0-2) | 17-16 | Lost 2 |
| » Starters: Gaylord Perry vs Bob Buhl | Fifth | 5½ out |
| Former Giant Eric Erickson dies in Jamestown, NY at the age of 71. |
| Thursday, May 20 |
| » Defeated Cubs (16-17), 2-0 | Wrigley Field (1-2) | 18-16 | |
| » Starters: Bob Shaw vs Larry Jackson | Fifth | 5 out |
| Friday, May 21 |
| » Defeated Astros (17-20), 8-1 | Astrodome (1-0) | 19-16 | Won 2 |
| » Starters: Ron Herbel vs Don Nottebart | Fourth | 4 out |
| Saturday, May 22 |
| » Defeated Astros (17-21), 10-1 | Astrodome (2-0) | 20-16 | Won 3 |
| » Starters: Juan Marichal vs Bob Bruce | Fourth | 4½ out |
| » Lost to Astros (18-21), 3-2 | Astrodome (2-1) | 20-17 | |
| » Starters: Jack Sanford vs Turk Farrell | Fourth | 4½ out |
| Future Giant Larry Carter is born in Charleston, WV. |
| Sunday, May 23 |
| » Defeated Astros (18-22), 5-2 | Astrodome (3-1) | 21-17 | |
| » Starters: Gaylord Perry vs Ken Johnson | Fourth | 3½ out |
| Former Giant Earl Webb dies in Jamestown, TN at the age of 68. |
| Monday, May 24 |
| » Lost to Braves (17-16), 4-3 | Candlestick Park (11-8) | 21-18 | |
| » Starters: Hank Fischer vs Bob Shaw | Fourth | 3½ out |
| Tuesday, May 25 |
| » Lost to Braves (18-16), 14-1 | Candlestick Park (11-9) | 21-19 | Lost 2 |
| » Starters: Wade Blasingame vs Ron Herbel | Fifth | 4½ out |
| Wednesday, May 26 |
| » Lost to Braves (19-16), 10-4 | Candlestick Park (11-10) | 21-20 | Lost 3 |
| » Starters: Tony Cloninger vs Juan Marichal | Fifth | 4½ out |
| Thursday, May 27 |
| » Defeated Reds (23-16), 9-2 | Candlestick Park (12-10) | 22-20 | |
| » Starters: Joe Nuxhall vs Gaylord Perry | Fifth | 4½ out |
| Friday, May 28 |
| » Defeated Reds (23-17), 12-7 | Candlestick Park (13-10) | 23-20 | Won 2 |
| » Starters: John Tsitouris vs Bob Shaw | Fifth | 3½ out |
| Saturday, May 29 |
| » Defeated Reds (23-18), 6-4 | Candlestick Park (14-10) | 24-20 | Won 3 |
| » Starters: Gerry Arrigo vs Jack Sanford | Fourth | 3½ out |
| Future Giant Charlie Hayes is born in Hattiesburg, MS. |
| Sunday, May 30 |
| » Defeated Cardinals (23-20), 3-2 | Candlestick Park (15-10) | 25-20 | Won 4 |
| » Starters: Bob Gibson vs Ron Herbel | Second | 3½ out |
| Monday, May 31 |
| » Defeated Cardinals (23-21), 4-1 | Candlestick Park (16-10) | 26-20 | Won 5 |
| » Starters: Curt Simmons vs Gaylord Perry | Second | 3 out |
| Tuesday, June 1 |
| » Lost to Cardinals (24-21), 2-1 | Candlestick Park (16-11) | 26-21 | |
| » Starters: Ray Sadecki vs Juan Marichal | Second | 3½ out |
| Thursday, June 3 |
| » Lost to Braves (23-19), 10-3 | County Stadium (0-1) | 26-22 | Lost 2 |
| » Starters: Bob Shaw vs Ken Johnson | Fourth | 5 out |
| » Major-league debuts: Bill Hands (Giants) |
| Friday, June 4 |
| » Lost to Reds (26-21), 4-2 | Crosley Field (0-1) | 26-23 | Lost 3 |
| » Starters: Gaylord Perry vs Joey Jay | Fourth | 5 out |
| Saturday, June 5 |
| » Defeated Reds (26-22), 1-0 | Crosley Field (1-1) | 27-23 | |
| » Starters: Juan Marichal vs Jim Maloney | Fourth | 4 out |
| Sunday, June 6 |
| » Lost to Reds (27-22), 6-0 | Crosley Field (1-2) | 27-24 | |
| » Starters: Bill Hands vs Sammy Ellis | Fourth | 4½ out |
| Tuesday, June 8 |
| » Defeated Mets (20-33), 2-1 | Shea Stadium (3-1) | 28-24 | |
| » Starters: Bob Shaw vs Galen Cisco | Fourth | 5 out |
| Wednesday, June 9 |
| » Defeated Mets (20-34), 4-2 | Shea Stadium (4-1) | 29-24 | Won 2 |
| » Starters: Gaylord Perry vs Jack Fisher | Fourth | 4 out |
| Thursday, June 10 |
| » Defeated Mets (20-35), 3-0 | Shea Stadium (5-1) | 30-24 | Won 3 |
| » Starters: Juan Marichal vs Gary Kroll | Fourth | 3 out |
| Future Giant Jim McNamara is born in Nashua, NH. |
| Friday, June 11 |
| » Lost to Pirates (28-26), 5-3 | Forbes Field (0-3) | 30-25 | |
| » Starters: Bill Hands vs Don Cardwell | Fourth | 4 out |
| Saturday, June 12 |
| » Defeated Pirates (28-27), 4-0 | Forbes Field (1-3) | 31-25 | |
| » Starters: Bob Shaw vs Bob Friend | Fourth | 4 out |
| Sunday, June 13 |
| » Lost to Pirates (29-27), 2-1 | Forbes Field (1-4) | 31-26 | |
| » Starters: Gaylord Perry vs Vern Law | Fourth | 5½ out |
| Tuesday, June 15 |
| » Defeated Dodgers (38-23), 2-1 | Dodger Stadium (2-3) | 32-26 | |
| » Starters: Juan Marichal vs Don Drysdale | Third | 4½ out |
| Wednesday, June 16 |
| » Lost to Dodgers (39-23), 2-1 | Dodger Stadium (2-4) | 32-27 | |
| » Starters: Bob Shaw vs Sandy Koufax | Fourth | 5½ out |
| Thursday, June 17 |
| » Lost to Dodgers (40-23), 3-0 | Dodger Stadium (2-5) | 32-28 | Lost 2 |
| » Starters: Gaylord Perry vs Claude Osteen | Fourth | 6½ out |
| Friday, June 18 |
| » Defeated Mets (21-42), 3-0 | Candlestick Park (17-11) | 33-28 | |
| » Starters: Galen Cisco vs Jack Sanford | Fourth | 5½ out |
| Saturday, June 19 |
| » Defeated Mets (21-43), 2-1 | Candlestick Park (18-11) | 34-28 | Won 2 |
| » Starters: Jack Fisher vs Juan Marichal | Fourth | 5½ out |
| Sunday, June 20 |
| » Defeated Pirates (33-30), 4-3 | Candlestick Park (19-11) | 35-28 | Won 3 |
| » Starters: Bob Friend vs Bob Shaw | Fourth | 4½ out |
| » Defeated Pirates (33-31), 7-3 | Candlestick Park (20-11) | 36-28 | Won 4 |
| » Starters: Don Schwall vs Bobby Bolin | Fourth | 4½ out |
| Tuesday, June 22 |
| » Lost to Pirates (34-31), 6-0 | Candlestick Park (20-12) | 36-29 | |
| » Starters: Vern Law vs Gaylord Perry | Fourth | 5 out |
| Wednesday, June 23 |
| » Defeated Pirates (34-32), 6-1 | Candlestick Park (21-12) | 37-29 | |
| » Starters: Bob Veale vs Jack Sanford | Fourth | 4½ out |
| Thursday, June 24 |
| » Lost to Phillies (34-32), 3-1 | Candlestick Park (21-13) | 37-30 | |
| » Starters: Jim Bunning vs Juan Marichal | Fourth | 4½ out |
| Friday, June 25 |
| » Defeated Phillies (34-33), 4-1 | Candlestick Park (22-13) | 38-30 | |
| » Starters: Bo Belinsky vs Bob Shaw | Third | 4½ out |
| Saturday, June 26 |
| » Defeated Phillies (34-34), 6-5 | Candlestick Park (23-13) | 39-30 | Won 2 |
| » Starters: Chris Short vs Gaylord Perry | Third | 3½ out |
| Sunday, June 27 |
| » Lost to Phillies (35-34), 6-0 | Candlestick Park (23-14) | 39-31 | |
| » Starters: Ray Culp vs Bobby Bolin | Third | 3½ out |
| Monday, June 28 |
| » Defeated Dodgers (44-30), 5-0 | Candlestick Park (24-14) | 40-31 | |
| » Starters: Don Drysdale vs Juan Marichal | Third | 2½ out |
| Tuesday, June 29 |
| » Lost to Dodgers (45-30), 9-3 | Candlestick Park (24-15) | 40-32 | |
| » Starters: Sandy Koufax vs Bob Shaw | Third | 3½ out |
| Wednesday, June 30 |
| » Lost to Astros (34-42), 6-4 | Astrodome (3-2) | 40-33 | Lost 2 |
| » Starters: Gaylord Perry vs Turk Farrell | Third | 4 out |
| Friday, July 2 |
| » Defeated Cubs (35-41), 4-0 | Wrigley Field (2-2) | 41-33 | |
| » Starters: Juan Marichal vs Cal Koonce | Third | 2½ out |
| Saturday, July 3 |
| » Lost to Cubs (36-41), 4-1 | Wrigley Field (2-3) | 41-34 | |
| » Starters: Bob Shaw vs Larry Jackson | Third | 3½ out |
| Sunday, July 4 |
| » Defeated Cubs (36-42), 7-4 | Wrigley Field (3-3) | 42-34 | |
| » Starters: Ron Herbel vs Bob Buhl | Third | 2½ out |
| Monday, July 5 |
| » Lost to Cardinals (39-41), 3-2 | Sportsman's Park III (2-2) | 42-35 | |
| » Starters: Gaylord Perry vs Ray Washburn | Third | 2½ out |
| Tuesday, July 6 |
| » Lost to Cardinals (40-41), 3-2 | Sportsman's Park III (2-3) | 42-36 | Lost 2 |
| » Starters: Juan Marichal vs Curt Simmons | Third | 3½ out |
| Former Giant Jimmy Ring dies in New York, NY at the age of 71. |
| Wednesday, July 7 |
| » Defeated Cardinals (40-42), 4-2 | Sportsman's Park III (3-3) | 43-36 | |
| » Starters: Bob Shaw vs Bob Gibson | Third | 2½ out |
| Thursday, July 8 |
| » Defeated Phillies (43-38), 10-2 | Shibe Park (2-0) | 44-36 | Won 2 |
| » Starters: Gaylord Perry vs Lew Burdette | Third | 3 out |
| » Lost to Phillies (44-38), 4-2 | Shibe Park (2-1) | 44-37 | |
| » Starters: Jack Sanford vs Ray Herbert | Third | 3 out |
| Friday, July 9 |
| » Lost to Phillies (45-38), 10-2 | Shibe Park (2-2) | 44-38 | Lost 2 |
| » Starters: Jack Sanford vs Jim Bunning | Fourth | 3½ out |
| Saturday, July 10 |
| » Defeated Phillies (45-39), 7-0 | Shibe Park (3-2) | 45-38 | |
| » Starters: Juan Marichal vs Ray Culp | Third | 3½ out |
| Thursday, July 15 |
| Future Giant Kirt Manwaring is born in Elmira, NY. |
| Friday, July 16 |
| » Defeated Astros (39-46), 2-1 | Candlestick Park (25-15) | 46-38 | Won 2 |
| » Starters: Bob Bruce vs Bob Shaw | Third | 3½ out |
| Saturday, July 17 |
| » Defeated Astros (39-47), 7-0 | Candlestick Park (26-15) | 47-38 | Won 3 |
| » Starters: Turk Farrell vs Juan Marichal | Third | 3½ out |
| Sunday, July 18 |
| » Lost to Astros (40-47), 5-2 | Candlestick Park (26-16) | 47-39 | |
| » Starters: Claude Raymond vs Gaylord Perry | Third | 4½ out |
| Monday, July 19 |
| » Lost to Cubs (42-50), 6-2 | Candlestick Park (26-17) | 47-40 | Lost 2 |
| » Starters: Dick Ellsworth vs Jack Sanford | Fourth | 5½ out |
| Tuesday, July 20 |
| » Defeated Cubs (42-51), 2-0 | Candlestick Park (27-17) | 48-40 | |
| » Starters: Larry Jackson vs Bob Shaw | Fourth | 5½ out |
| Wednesday, July 21 |
| » Defeated Reds (52-41), 5-4 | Candlestick Park (28-17) | 49-40 | Won 2 |
| » Starters: John Tsitouris vs Juan Marichal | Fourth | 4½ out |
| Thursday, July 22 |
| » Lost to Reds (53-41), 5-4 | Candlestick Park (28-18) | 49-41 | |
| » Starters: Jim Maloney vs Warren Spahn | Fourth | 4½ out |
| Friday, July 23 |
| » Defeated Braves (51-41), 5-1 | Candlestick Park (29-18) | 50-41 | |
| » Starters: Ken Johnson vs Ron Herbel | Fourth | 3½ out |
| Saturday, July 24 |
| » Defeated Braves (51-42), 4-2 | Candlestick Park (30-18) | 51-41 | Won 2 |
| » Starters: Hank Fischer vs Bob Shaw | Third | 3½ out |
| Sunday, July 25 |
| » Defeated Braves (51-43), 2-1 | Candlestick Park (31-18) | 52-41 | Won 3 |
| » Starters: Bob Sadowski vs Bob Shaw | Third | 3½ out |
| Monday, July 26 |
| » Lost to Cardinals (49-49), 7-4 | Candlestick Park (31-19) | 52-42 | |
| » Starters: Bob Gibson vs Juan Marichal | Third | 3½ out |
| Tuesday, July 27 |
| » Lost to Cardinals (50-49), 3-0 | Candlestick Park (31-20) | 52-43 | Lost 2 |
| » Starters: Bob Purkey vs Warren Spahn | Fourth | 4½ out |
| Wednesday, July 28 |
| » Defeated Cardinals (50-50), 8-5 | Candlestick Park (32-20) | 53-43 | |
| » Starters: Tracy Stallard vs Ron Herbel | Fourth | 3½ out |
| Friday, July 30 |
| » Defeated Braves (54-44), 9-2 | County Stadium (1-1) | 54-43 | Won 2 |
| » Starters: Bob Shaw vs Hank Fischer | Third | 3½ out |
| Saturday, July 31 |
| » Defeated Braves (54-45), 3-1 | County Stadium (2-1) | 55-43 | Won 3 |
| » Starters: Juan Marichal vs Denny Lemaster | Third | 3½ out |
| Sunday, August 1 |
| » Lost to Braves (55-45), 4-2 | County Stadium (2-2) | 55-44 | |
| » Starters: Ron Herbel vs Tony Cloninger | Fourth | 4 out |
| » Lost to Braves (56-45), 6-3 | County Stadium (2-3) | 55-45 | Lost 2 |
| » Starters: Jack Sanford vs Wade Blasingame | Fourth | 4 out |
| Monday, August 2 |
| » Lost to Braves (57-45), 4-2 | County Stadium (2-4) | 55-46 | Lost 3 |
| » Starters: Gaylord Perry vs Ken Johnson | Fourth | 4 out |
| Tuesday, August 3 |
| » Defeated Reds (60-46), 6-3 | Crosley Field (2-2) | 56-46 | |
| » Starters: Bob Shaw vs Sammy Ellis | Fourth | 3½ out |
| Wednesday, August 4 |
| » Defeated Reds (60-47), 4-3 | Crosley Field (3-2) | 57-46 | Won 2 |
| » Starters: Juan Marichal vs Jim O'Toole | Fourth | 3 out |
| Thursday, August 5 |
| » Defeated Reds (60-48), 18-7 | Crosley Field (4-2) | 58-46 | Won 3 |
| » Starters: Ron Herbel vs John Tsitouris | Second | 3 out |
| Friday, August 6 |
| » Defeated Cardinals (55-54), 3-2 | Sportsman's Park III (4-3) | 59-46 | Won 4 |
| » Starters: Gaylord Perry vs Ray Sadecki | Second | 3 out |
| Saturday, August 7 |
| » Defeated Cardinals (55-55), 10-4 | Sportsman's Park III (5-3) | 60-46 | Won 5 |
| » Starters: Bob Shaw vs Tracy Stallard | Second | 3 out |
| Sunday, August 8 |
| » Defeated Cardinals (55-56), 6-4 | Sportsman's Park III (6-3) | 61-46 | Won 6 |
| » Starters: Warren Spahn vs Curt Simmons | Second | 3 out |
| Tuesday, August 10 |
| » Defeated Pirates (59-56), 4-3 | Candlestick Park (33-20) | 62-46 | Won 7 |
| » Starters: Don Cardwell vs Juan Marichal | Second | 3 out |
| Thursday, August 12 |
| » Defeated Pirates (59-57), 4-3 | Candlestick Park (34-20) | 63-46 | Won 8 |
| » Starters: Bob Friend vs Bob Shaw | Second | 2½ out |
| » Lost to Pirates (60-57), 5-2 | Candlestick Park (34-21) | 63-47 | |
| » Starters: Vern Law vs Gaylord Perry | Second | 2½ out |
| Friday, August 13 |
| » Lost to Phillies (62-53), 3-2 | Candlestick Park (34-22) | 63-48 | Lost 2 |
| » Starters: Ray Herbert vs Warren Spahn | Second | 2½ out |
| Saturday, August 14 |
| » Lost to Phillies (63-53), 4-2 | Candlestick Park (34-23) | 63-49 | Lost 3 |
| » Starters: Jim Bunning vs Juan Marichal | Third | 3½ out |
| Sunday, August 15 |
| » Defeated Phillies (63-54), 15-9 | Candlestick Park (35-23) | 64-49 | |
| » Starters: Ray Culp vs Masanori Murakami | Third | 2½ out |
| Monday, August 16 |
| » Defeated Mets (36-82), 3-2 | Candlestick Park (36-23) | 65-49 | Won 2 |
| » Starters: Tom Parsons vs Bob Shaw | Third | 2½ out |
| Tuesday, August 17 |
| » Defeated Mets (36-83), 3-2 | Candlestick Park (37-23) | 66-49 | Won 3 |
| » Starters: Jack Fisher vs Gaylord Perry | Third | 2½ out |
| Wednesday, August 18 |
| » Defeated Mets (36-84), 5-0 | Candlestick Park (38-23) | 67-49 | Won 4 |
| » Starters: Larry Miller vs Juan Marichal | Third | 1 out |
| » Major-league debuts: Tito Fuentes (Giants) |
| Thursday, August 19 |
| » Lost to Dodgers (71-51), 8-5 | Candlestick Park (38-24) | 67-50 | |
| » Starters: Don Drysdale vs Warren Spahn | Third | 2½ out |
| Friday, August 20 |
| » Defeated Dodgers (71-52), 5-1 | Candlestick Park (39-24) | 68-50 | |
| » Starters: Howie Reed vs Bob Shaw | Third | 1 out |
| Saturday, August 21 |
| » Lost to Dodgers (72-52), 6-4 | Candlestick Park (39-25) | 68-51 | |
| » Starters: Claude Osteen vs Bobby Bolin | Third | 2½ out |
| Sunday, August 22 |
| » Defeated Dodgers (72-53), 4-3 | Candlestick Park (40-25) | 69-51 | |
| » Starters: Sandy Koufax vs Juan Marichal | Second | 2½ out |
| Monday, August 23 |
| » Lost to Pirates (66-61), 6-2 | Forbes Field (1-5) | 69-52 | |
| » Starters: Warren Spahn vs Vern Law | Third | 2½ out |
| Tuesday, August 24 |
| » Lost to Pirates (67-61), 5-2 | Forbes Field (1-6) | 69-53 | Lost 2 |
| » Starters: Bob Shaw vs Don Cardwell | Third | 2½ out |
| Wednesday, August 25 |
| » Tied Pirates, 3-3 | Forbes Field (1-6) | 69-53 | |
| » Starters: Bobby Bolin vs Bob Friend | Third | 3 out |
| Former Giant Moonlight Graham dies in Chisholm, MN at the age of 89. |
| Thursday, August 26 |
| » Lost to Pirates (68-61), 8-0 | Forbes Field (1-7) | 69-54 | Lost 3 |
| » Starters: Ron Herbel vs Bob Veale | Third | 2½ out |
| » Lost to Pirates (69-61), 6-5 | Forbes Field (1-8) | 69-55 | Lost 4 |
| » Starters: Gaylord Perry vs Tommie Sisk | Third | 2½ out |
| Friday, August 27 |
| » Defeated Mets (42-87), 9-2 | Shea Stadium (6-1) | 70-55 | |
| » Starters: Warren Spahn vs Darrell Sutherland | Second | 2½ out |
| Saturday, August 28 |
| » Lost to Mets (43-87), 3-0 | Shea Stadium (6-2) | 70-56 | |
| » Starters: Bob Shaw vs Galen Cisco | Third | 2½ out |
| Sunday, August 29 |
| » Defeated Mets (43-88), 8-3 | Shea Stadium (7-2) | 71-56 | |
| » Starters: Bobby Bolin vs Jack Fisher | Second | 2½ out |
| Tuesday, August 31 |
| » Defeated Phillies (67-63), 2-1 | Shibe Park (4-2) | 72-56 | Won 2 |
| » Starters: Ron Herbel vs Jim Bunning | Second | 1½ out |
| » Lost to Phillies (68-63), 2-0 | Shibe Park (4-3) | 72-57 | |
| » Starters: Warren Spahn vs Lew Burdette | Second | 1½ out |
| Thursday, September 2 |
| » Lost to Phillies (69-63), 4-3 | Shibe Park (4-4) | 72-58 | Lost 2 |
| » Starters: Juan Marichal vs Chris Short | Second | 2 out |
| » Defeated Phillies (69-64), 5-2 | Shibe Park (5-4) | 73-58 | |
| » Starters: Bob Shaw vs Ray Herbert | Second | 2 out |
| » Major-league debuts: Bill Sorrell (Phillies) |
| Friday, September 3 |
| » Lost to Cubs (65-73), 5-4 | Wrigley Field (3-4) | 73-59 | |
| » Starters: Bobby Bolin vs Bill Faul | Third | 2 out |
| Saturday, September 4 |
| » Defeated Cubs (65-74), 7-3 | Wrigley Field (4-4) | 74-59 | |
| » Starters: Ron Herbel vs Bob Buhl | Fourth | 2 out |
| » Major-league debuts: Ken Holtzman (Cubs) |
| Sunday, September 5 |
| » Defeated Cubs (65-75), 4-2 | Wrigley Field (5-4) | 75-59 | Won 2 |
| » Starters: Juan Marichal vs Dick Ellsworth | Third | 2 out |
| Monday, September 6 |
| » Defeated Dodgers (79-60), 7-6 | Dodger Stadium (3-5) | 76-59 | Won 3 |
| » Starters: Warren Spahn vs Don Drysdale | Second | 2 out |
| Tuesday, September 7 |
| » Defeated Dodgers (79-61), 3-1 | Dodger Stadium (4-5) | 77-59 | Won 4 |
| » Starters: Bob Shaw vs Claude Osteen | First | -- |
| Wednesday, September 8 |
| » Defeated Astros (60-80), 12-3 | Candlestick Park (41-25) | 78-59 | Won 5 |
| » Starters: Don Nottebart vs Bobby Bolin | First | -- |
| Thursday, September 9 |
| » Defeated Astros (60-81), 4-0 | Candlestick Park (42-25) | 79-59 | Won 6 |
| » Starters: Bob Bruce vs Juan Marichal | First | -- |
| Friday, September 10 |
| » Defeated Cubs (65-78), 5-2 | Candlestick Park (43-25) | 80-59 | Won 7 |
| » Starters: Dick Ellsworth vs Ron Herbel | First | -- |
| » Major-league debuts: Ollie Brown (Giants) |
| Saturday, September 11 |
| » Defeated Cubs (65-79), 6-4 | Candlestick Park (44-25) | 81-59 | Won 8 |
| » Starters: Bill Faul vs Bob Shaw | First | -- |
| » Major-league debuts: Chuck Hartenstein (Cubs) |
| Sunday, September 12 |
| » Defeated Cubs (65-80), 4-3 | Candlestick Park (45-25) | 82-59 | Won 9 |
| » Starters: Larry Jackson vs Bobby Bolin | First | -- |
| » Defeated Cubs (65-81), 9-2 | Candlestick Park (46-25) | 83-59 | Won 10 |
| » Starters: Bob Buhl vs Warren Spahn | First | -- |
| Monday, September 13 |
| » Defeated Astros (61-84), 5-1 | Astrodome (4-2) | 84-59 | Won 11 |
| » Starters: Juan Marichal vs Don Nottebart | First | -- |
| Tuesday, September 14 |
| » Defeated Astros (61-85), 7-5 | Astrodome (5-2) | 85-59 | Won 12 |
| » Starters: Ron Herbel vs Bob Bruce | First | -- |
| Wednesday, September 15 |
| » Defeated Astros (61-86), 3-2 | Astrodome (6-2) | 86-59 | Won 13 |
| » Starters: Bob Shaw vs Robin Roberts | First | -- |
| » Major-league debuts: Chuck Harrison (Astros) |
| Thursday, September 16 |
| » Defeated Astros (61-87), 5-1 | Astrodome (7-2) | 87-59 | Won 14 |
| » Starters: Bobby Bolin vs Turk Farrell | First | -- |
| » Major-league debuts: Jim Ray (Astros) |
| Friday, September 17 |
| » Lost to Braves (81-66), 9-1 | County Stadium (2-5) | 87-60 | |
| » Starters: Juan Marichal vs Phil Niekro | First | -- |
| » Major-league debuts: Bob Barton (Giants) |
| Saturday, September 18 |
| » Defeated Braves (81-67), 2-0 | County Stadium (3-5) | 88-60 | |
| » Starters: Ron Herbel vs Hank Fischer | First | -- |
| Sunday, September 19 |
| » Defeated Braves (81-68), 4-2 | County Stadium (4-5) | 89-60 | Won 2 |
| » Starters: Bob Shaw vs Tony Cloninger | First | -- |
| Monday, September 20 |
| » Defeated Reds (85-66), 4-0 | Crosley Field (5-2) | 90-60 | Won 3 |
| » Starters: Bobby Bolin vs Jim Maloney | First | -- |
| Tuesday, September 21 |
| » Lost to Reds (86-66), 7-4 | Crosley Field (5-3) | 90-61 | |
| » Starters: Bob Shaw vs Jim O'Toole | First | -- |
| Wednesday, September 22 |
| » Lost to Reds (87-66), 7-1 | Crosley Field (5-4) | 90-62 | Lost 2 |
| » Starters: Juan Marichal vs Sammy Ellis | First | -- |
| Friday, September 24 |
| » Lost to Braves (82-71), 8-2 | Candlestick Park (46-26) | 90-63 | Lost 3 |
| » Starters: Tony Cloninger vs Ron Herbel | First | -- |
| Saturday, September 25 |
| » Defeated Braves (82-72), 7-5 | Candlestick Park (47-26) | 91-63 | |
| » Starters: Ken Johnson vs Bob Shaw | First | -- |
| Sunday, September 26 |
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