| Tuesday, February 25 |
| Future Tiger Rich Rowland is born in Cloverdale, CA. |
| Sunday, March 8 |
| Future Tiger Lance McCullers is born in Tampa, FL. |
| Thursday, April 2 |
| Future Tiger Pete Incaviglia is born in Pebble Beach, CA. |
| Monday, April 6 |
| Future Tiger Ken Williams is born in Berkeley, CA. |
| Wednesday, April 8 |
| Former Tiger George Moriarty dies in Miami, FL at the age of 80. |
| Friday, April 10 |
| Future Tiger Eric King is born in Oxnard, CA. |
| Monday, April 13 |
| » Major-league debuts: Bobby Knoop (Angels) |
| Future Tiger Doug Strange is born in Greenville, SC. |
| Tuesday, April 14 |
| » Defeated Athletics (0-1), 7-3 | Tiger Stadium (1-0) | 1-0 | |
| » Starters: Orlando Pena vs Phil Regan | First | -- |
| » Major-league debuts: Vern Handrahan (Athletics) |
| Wednesday, April 15 |
| » Major-league debuts: Dick Kelley and Phil Niekro (Braves) |
| Friday, April 17 |
| » Lost to Angels (2-1), 8-3 | Tiger Stadium (1-1) | 1-1 | |
| » Starters: Dean Chance vs Frank Lary | Fourth | 1½ out |
| Saturday, April 18 |
| » Defeated Angels (2-2), 3-2 | Tiger Stadium (2-1) | 2-1 | |
| » Starters: Ken McBride vs Mickey Lolich | Third | 1½ out |
| Sunday, April 19 |
| » Lost to Twins (4-1), 12-3 | Tiger Stadium (2-2) | 2-2 | |
| » Starters: Camilo Pascual vs Phil Regan | Third | 1 out |
| » Defeated Twins (4-2), 3-1 | Tiger Stadium (3-2) | 3-2 | |
| » Starters: Jim Roland vs Dave Wickersham | Third | 1 out |
| Tuesday, April 21 |
| » Defeated Angels (2-3), 6-4 | Dodger Stadium (1-0) | 4-2 | Won 2 |
| » Starters: Frank Lary vs Dean Chance | Second | ½ out |
| Wednesday, April 22 |
| » Lost to Angels (3-3), 3-2 | Dodger Stadium (1-1) | 4-3 | |
| » Starters: Hank Aguirre vs Bo Belinsky | Fifth | 1 out |
| Friday, April 24 |
| » Defeated Twins (5-4), 5-0 | Metropolitan Stadium (1-0) | 5-3 | |
| » Starters: Mickey Lolich vs Dick Stigman | Third | 1½ out |
| Saturday, April 25 |
| » Defeated Twins (5-5), 5-2 | Metropolitan Stadium (2-0) | 6-3 | Won 2 |
| » Starters: Dave Wickersham vs Camilo Pascual | Second | 1½ out |
| Sunday, April 26 |
| » Lost to Twins (6-5), 3-2 | Metropolitan Stadium (2-1) | 6-4 | |
| » Starters: Phil Regan vs Jim Kaat | Second | 1½ out |
| Tuesday, April 28 |
| » Lost to Athletics (3-5), 5-1 | Municipal Stadium (0-1) | 6-5 | Lost 2 |
| » Starters: Frank Lary vs Diego Segui | Fourth | 1½ out |
| Wednesday, April 29 |
| » Defeated Athletics (3-6), 5-4 | Municipal Stadium (1-1) | 7-5 | |
| » Starters: Hank Aguirre vs John O'Donoghue | Second | 2 out |
| Thursday, April 30 |
| » Lost to Athletics (4-6), 10-3 | Municipal Stadium (1-2) | 7-6 | |
| » Starters: Mickey Lolich vs Orlando Pena | Fourth | 2 out |
| Friday, May 1 |
| Future Tiger Dan Gakeler is born in Mount Holly, NJ. |
| Saturday, May 2 |
| » Defeated Red Sox (5-8), 4-0 | Fenway Park (1-0) | 8-6 | |
| » Starters: Dave Wickersham vs Bill Monbouquette | Fourth | 2 out |
| Sunday, May 3 |
| » Lost to Red Sox (6-8), 11-7 | Fenway Park (1-1) | 8-7 | |
| » Starters: Phil Regan vs Jack Lamabe | Third | 1½ out |
| Tuesday, May 5 |
| » Lost to Yankees (7-6), 4-3 | Yankee Stadium (0-1) | 8-8 | Lost 2 |
| » Starters: Hank Aguirre vs Whitey Ford | Fifth | 2 out |
| Wednesday, May 6 |
| » Defeated Red Sox (7-10), 6-3 | Tiger Stadium (4-2) | 9-8 | |
| » Starters: Bill Monbouquette vs Dave Wickersham | Third | 2 out |
| Thursday, May 7 |
| » Lost to Red Sox (8-10), 7-3 | Tiger Stadium (4-3) | 9-9 | |
| » Starters: Jack Lamabe vs Phil Regan | Fourth | 3 out |
| Friday, May 8 |
| » Lost to Orioles (10-9), 4-3 | Tiger Stadium (4-4) | 9-10 | Lost 2 |
| » Starters: Robin Roberts vs Mickey Lolich | Sixth | 3½ out |
| Saturday, May 9 |
| » Lost to Orioles (11-9), 7-6 | Tiger Stadium (4-5) | 9-11 | Lost 3 |
| » Starters: Chuck Estrada vs Hank Aguirre | Sixth | 3½ out |
| Sunday, May 10 |
| » Lost to Orioles (12-9), 2-1 | Tiger Stadium (4-6) | 9-12 | Lost 4 |
| » Starters: Milt Pappas vs Dave Wickersham | Eighth | 5 out |
| » Lost to Orioles (13-9), 7-1 | Tiger Stadium (4-7) | 9-13 | Lost 5 |
| » Starters: Wally Bunker vs Ed Rakow | Eighth | 5 out |
| Monday, May 11 |
| Future Tiger Billy Bean is born in Santa Ana, CA. |
| Tuesday, May 12 |
| » Defeated Yankees (13-8), 7-2 | Tiger Stadium (5-7) | 10-13 | |
| » Starters: Al Downing vs Mickey Lolich | Seventh | 4 out |
| Wednesday, May 13 |
| » Tied Yankees, 1-1 | Tiger Stadium (5-7) | 10-13 | |
| » Starters: Whitey Ford vs Hank Aguirre | Seventh | 4½ out |
| Thursday, May 14 |
| » Defeated Yankees (13-9), 7-3 | Tiger Stadium (6-7) | 11-13 | Won 2 |
| » Starters: Jim Bouton vs Phil Regan | Sixth | 3½ out |
| Friday, May 15 |
| » Lost to Indians (15-9), 10-6 | Tiger Stadium (6-8) | 11-14 | |
| » Starters: Pedro Ramos vs Dave Wickersham | Sixth | 4½ out |
| Saturday, May 16 |
| » Lost to Indians (16-9), 2-1 | Tiger Stadium (6-9) | 11-15 | Lost 2 |
| » Starters: Jack Kralick vs Ed Rakow | Seventh | 5½ out |
| Sunday, May 17 |
| » Defeated Indians (16-10), 3-1 | Tiger Stadium (7-9) | 12-15 | |
| » Starters: Tommy John vs Hank Aguirre | Sixth | 4 out |
| » Defeated Indians (16-11), 4-1 | Tiger Stadium (8-9) | 13-15 | Won 2 |
| » Starters: Mudcat Grant vs Mickey Lolich | Sixth | 4 out |
| Monday, May 18 |
| » Defeated Senators (14-20), 7-6 | Robert F. Kennedy Stadium (1-0) | 14-15 | Won 3 |
| » Starters: Frank Lary vs Jim Hannan | Sixth | 3½ out |
| Tuesday, May 19 |
| » Defeated Senators (14-21), 5-2 | Robert F. Kennedy Stadium (2-0) | 15-15 | Won 4 |
| » Starters: Dave Wickersham vs Buster Narum | Sixth | 3½ out |
| Wednesday, May 20 |
| » Lost to Senators (15-21), 10-3 | Robert F. Kennedy Stadium (2-1) | 15-16 | |
| » Starters: Ed Rakow vs Claude Osteen | Fifth | 4 out |
| » Major-league debuts: Joe Sparma (Tigers) |
| Thursday, May 21 |
| » Lost to Senators (16-21), 8-2 | Robert F. Kennedy Stadium (2-2) | 15-17 | Lost 2 |
| » Starters: Jack Hamilton vs Bennie Daniels | Fifth | 4½ out |
| Friday, May 22 |
| » Lost to Indians (17-12), 5-3 | Cleveland Stadium (0-1) | 15-18 | Lost 3 |
| » Starters: Mickey Lolich vs Jack Kralick | Fifth | 5½ out |
| Saturday, May 23 |
| » Lost to Indians (18-12), 11-9 | Cleveland Stadium (0-2) | 15-19 | Lost 4 |
| » Starters: Phil Regan vs Tommy John | Seventh | 6½ out |
| Sunday, May 24 |
| » Defeated Indians (18-13), 7-5 | Cleveland Stadium (1-2) | 16-19 | |
| » Starters: Dave Wickersham vs Pedro Ramos | Seventh | 6 out |
| Monday, May 25 |
| » Defeated Orioles (23-14), 5-3 | Memorial Stadium (1-0) | 17-19 | Won 2 |
| » Starters: Hank Aguirre vs Steve Barber | Seventh | 6 out |
| Tuesday, May 26 |
| » Lost to Orioles (24-14), 2-1 | Memorial Stadium (1-1) | 17-20 | |
| » Starters: Mickey Lolich vs Wally Bunker | Seventh | 6½ out |
| Wednesday, May 27 |
| » Defeated Orioles (24-15), 6-3 | Memorial Stadium (2-1) | 18-20 | |
| » Starters: Phil Regan vs Dave McNally | Seventh | 6 out |
| Friday, May 29 |
| » Lost to White Sox (21-11), 4-1 | Tiger Stadium (8-10) | 18-21 | |
| » Starters: John Buzhardt vs Dave Wickersham | Seventh | 6½ out |
| Saturday, May 30 |
| » Lost to White Sox (22-11), 10-4 | Tiger Stadium (8-11) | 18-22 | Lost 2 |
| » Starters: Joe Horlen vs Hank Aguirre | Seventh | 7½ out |
| Sunday, May 31 |
| » Lost to White Sox (23-11), 5-3 | Tiger Stadium (8-12) | 18-23 | Lost 3 |
| » Starters: Eddie Fisher vs Mickey Lolich | Sixth | 9½ out |
| » Lost to White Sox (24-11), 8-3 | Tiger Stadium (8-13) | 18-24 | Lost 4 |
| » Starters: Gary Peters vs Ed Rakow | Sixth | 9½ out |
| Wednesday, June 3 |
| » Lost to Senators (20-29), 6-2 | Tiger Stadium (8-14) | 18-25 | Lost 5 |
| » Starters: Claude Osteen vs Dave Wickersham | Seventh | 11 out |
| Thursday, June 4 |
| Future Tiger Steve Searcy is born in Knoxville, TN. |
| Friday, June 5 |
| » Lost to White Sox (27-13), 4-3 | Comiskey Park I (0-1) | 18-26 | Lost 6 |
| » Starters: Mickey Lolich vs Juan Pizarro | Seventh | 11 out |
| Saturday, June 6 |
| » Defeated White Sox (27-14), 4-3 | Comiskey Park I (1-1) | 19-26 | |
| » Starters: Denny McLain vs Gary Peters | Sixth | 11 out |
| Sunday, June 7 |
| » Lost to White Sox (28-14), 8-3 | Comiskey Park I (1-2) | 19-27 | |
| » Starters: Phil Regan vs John Buzhardt | Eighth | 12 out |
| » Lost to White Sox (29-14), 2-1 | Comiskey Park I (1-3) | 19-28 | Lost 2 |
| » Starters: Hank Aguirre vs Joe Horlen | Eighth | 12 out |
| Monday, June 8 |
| » Defeated Twins (28-23), 10-5 | Tiger Stadium (9-14) | 20-28 | |
| » Starters: Jim Roland vs Dave Wickersham | Seventh | 11½ out |
| Tuesday, June 9 |
| » Defeated Twins (28-24), 16-1 | Tiger Stadium (10-14) | 21-28 | Won 2 |
| » Starters: Jim Kaat vs Denny McLain | Seventh | 11½ out |
| Wednesday, June 10 |
| » Defeated Twins (28-25), 5-4 | Tiger Stadium (11-14) | 22-28 | Won 3 |
| » Starters: Lee Stange vs Mickey Lolich | Seventh | 11½ out |
| Thursday, June 11 |
| » Lost to Twins (29-25), 4-2 | Tiger Stadium (11-15) | 22-29 | |
| » Starters: Dick Stigman vs Ed Rakow | Eighth | 11½ out |
| Saturday, June 13 |
| » Defeated Angels (24-34), 8-5 | Tiger Stadium (12-15) | 23-29 | |
| » Starters: Fred Newman vs Dave Wickersham | Seventh | 9½ out |
| Sunday, June 14 |
| » Defeated Angels (24-35), 6-5 | Tiger Stadium (13-15) | 24-29 | Won 2 |
| » Starters: Ken McBride vs Mickey Lolich | Seventh | 8½ out |
| » Defeated Angels (24-36), 6-4 | Tiger Stadium (14-15) | 25-29 | Won 3 |
| » Starters: Barry Latman vs Denny McLain | Seventh | 8½ out |
| Tuesday, June 16 |
| » Lost to Athletics (21-36), 7-4 | Tiger Stadium (14-16) | 25-30 | |
| » Starters: Diego Segui vs Hank Aguirre | Seventh | 9 out |
| » Lost to Athletics (22-36), 6-0 | Tiger Stadium (14-17) | 25-31 | Lost 2 |
| » Starters: Ted Bowsfield vs Phil Regan | Seventh | 9 out |
| Wednesday, June 17 |
| » Defeated Athletics (22-37), 3-2 | Tiger Stadium (15-17) | 26-31 | |
| » Starters: Orlando Pena vs Dave Wickersham | Seventh | 9 out |
| Thursday, June 18 |
| » Lost to Athletics (23-37), 3-2 | Tiger Stadium (15-18) | 26-32 | |
| » Starters: John O'Donoghue vs Ed Rakow | Seventh | 9 out |
| Friday, June 19 |
| » Lost to Twins (33-29), 7-6 | Metropolitan Stadium (2-2) | 26-33 | Lost 2 |
| » Starters: Mickey Lolich vs Jim Kaat | Seventh | 10½ out |
| Saturday, June 20 |
| » Defeated Twins (33-30), 8-7 | Metropolitan Stadium (3-2) | 27-33 | |
| » Starters: Phil Regan vs Mudcat Grant | Seventh | 10½ out |
| Sunday, June 21 |
| » Defeated Twins (33-31), 4-2 | Metropolitan Stadium (4-2) | 28-33 | Won 2 |
| » Starters: Dave Wickersham vs Dick Stigman | Seventh | 9½ out |
| Tuesday, June 23 |
| » Lost to Athletics (26-39), 2-1 | Municipal Stadium (1-3) | 28-34 | |
| » Starters: Joe Sparma vs John O'Donoghue | Seventh | 10 out |
| » Defeated Athletics (26-40), 9-3 | Municipal Stadium (2-3) | 29-34 | |
| » Starters: Mickey Lolich vs Dan Pfister | Seventh | 10 out |
| Wednesday, June 24 |
| » Defeated Athletics (26-41), 9-5 | Municipal Stadium (3-3) | 30-34 | Won 2 |
| » Starters: Ed Rakow vs Diego Segui | Seventh | 10 out |
| Friday, June 26 |
| » Defeated Yankees (38-27), 1-0 | Yankee Stadium (1-1) | 31-34 | Won 3 |
| » Starters: Dave Wickersham vs Al Downing | Eighth | 10½ out |
| Saturday, June 27 |
| » Lost to Yankees (39-27), 5-4 | Yankee Stadium (1-2) | 31-35 | |
| » Starters: Denny McLain vs Whitey Ford | Eighth | 11½ out |
| Sunday, June 28 |
| » Lost to Yankees (40-27), 8-6 | Yankee Stadium (1-3) | 31-36 | Lost 2 |
| » Starters: Hank Aguirre vs Steve Hamilton | Eighth | 12 out |
| » Defeated Yankees (40-28), 6-5 | Yankee Stadium (2-3) | 32-36 | |
| » Starters: Mickey Lolich vs Rollie Sheldon | Eighth | 12 out |
| Monday, June 29 |
| » Lost to Senators (30-45), 5-3 | Robert F. Kennedy Stadium (2-3) | 32-37 | |
| » Starters: Phil Regan vs Claude Osteen | Eighth | 13 out |
| Tuesday, June 30 |
| » Lost to Senators (31-45), 6-5 | Robert F. Kennedy Stadium (2-4) | 32-38 | Lost 2 |
| » Starters: Dave Wickersham vs Jim Hannan | Eighth | 13 out |
| Wednesday, July 1 |
| » Defeated Indians (33-38), 3-1 | Tiger Stadium (16-18) | 33-38 | |
| » Starters: Tommy John vs Hank Aguirre | Sixth | 13 out |
| Thursday, July 2 |
| » Defeated Indians (33-39), 9-1 | Tiger Stadium (17-18) | 34-38 | Won 2 |
| » Starters: Pedro Ramos vs Mickey Lolich | Sixth | 12 out |
| Friday, July 3 |
| » Lost to Senators (32-47), 3-1 | Tiger Stadium (17-19) | 34-39 | |
| » Starters: Bennie Daniels vs Ed Rakow | Fifth | 12½ out |
| » Defeated Senators (32-48), 2-1 | Tiger Stadium (18-19) | 35-39 | |
| » Starters: Dave Stenhouse vs Phil Regan | Fifth | 12½ out |
| Saturday, July 4 |
| » Defeated Senators (32-49), 5-3 | Tiger Stadium (19-19) | 36-39 | Won 2 |
| » Starters: Claude Osteen vs Dave Wickersham | Fifth | 12 out |
| Sunday, July 5 |
| » Defeated Senators (32-50), 7-6 | Tiger Stadium (20-19) | 37-39 | Won 3 |
| » Starters: Buster Narum vs Denny McLain | Fifth | 10½ out |
| » Defeated Senators (32-51), 3-0 | Tiger Stadium (21-19) | 38-39 | Won 4 |
| » Starters: Alan Koch vs Joe Sparma | Fifth | 10½ out |
| Thursday, July 9 |
| » Defeated Red Sox (38-42), 4-3 | Tiger Stadium (22-19) | 39-39 | Won 5 |
| » Starters: Bill Monbouquette vs Dave Wickersham | Fifth | 11 out |
| Friday, July 10 |
| » Lost to Red Sox (39-42), 7-6 | Tiger Stadium (22-20) | 39-40 | |
| » Starters: Earl Wilson vs Phil Regan | Fifth | 10½ out |
| » Defeated Red Sox (39-43), 8-3 | Tiger Stadium (23-20) | 40-40 | |
| » Starters: Dave Morehead vs Ed Rakow | Fifth | 10½ out |
| Saturday, July 11 |
| » Defeated Red Sox (39-44), 8-1 | Tiger Stadium (24-20) | 41-40 | Won 2 |
| » Starters: Arnold Earley vs Joe Sparma | Fifth | 10½ out |
| Sunday, July 12 |
| » Lost to Orioles (52-29), 4-2 | Tiger Stadium (24-21) | 41-41 | |
| » Starters: Robin Roberts vs Hank Aguirre | Fifth | 10½ out |
| » Defeated Orioles (52-30), 4-3 | Tiger Stadium (25-21) | 42-41 | |
| » Starters: Chuck Estrada vs Mickey Lolich | Fifth | 10½ out |
| Monday, July 13 |
| » Defeated Orioles (52-31), 4-3 | Tiger Stadium (26-21) | 43-41 | Won 2 |
| » Starters: Wally Bunker vs Dave Wickersham | Fifth | 9½ out |
| Tuesday, July 14 |
| » Defeated Angels (41-47), 4-3 | Dodger Stadium (2-1) | 44-41 | Won 3 |
| » Starters: Ed Rakow vs Bo Belinsky | Fifth | 8½ out |
| Wednesday, July 15 |
| » Lost to Angels (42-47), 5-4 | Dodger Stadium (2-2) | 44-42 | |
| » Starters: Joe Sparma vs Barry Latman | Fifth | 9½ out |
| » Lost to Angels (43-47), 1-0 | Dodger Stadium (2-3) | 44-43 | Lost 2 |
| » Starters: Phil Regan vs Dean Chance | Fifth | 9½ out |
| Friday, July 17 |
| » Lost to Orioles (54-33), 5-0 | Memorial Stadium (2-2) | 44-44 | Lost 3 |
| » Starters: Dave Wickersham vs Robin Roberts | Fifth | 10½ out |
| Saturday, July 18 |
| » Lost to Orioles (55-33), 6-1 | Memorial Stadium (2-3) | 44-45 | Lost 4 |
| » Starters: Hank Aguirre vs Milt Pappas | Fifth | 10½ out |
| » Defeated Orioles (55-34), 3-0 | Memorial Stadium (3-3) | 45-45 | |
| » Starters: Mickey Lolich vs Dave Vineyard | Fifth | 10½ out |
| Sunday, July 19 |
| » Lost to Orioles (56-34), 5-4 | Memorial Stadium (3-4) | 45-46 | |
| » Starters: Denny McLain vs Wally Bunker | Sixth | 11½ out |
| Monday, July 20 |
| » Defeated Red Sox (45-49), 7-5 | Fenway Park (2-1) | 46-46 | |
| » Starters: Phil Regan vs Bob Heffner | Fifth | 11 out |
| Tuesday, July 21 |
| » Lost to Red Sox (46-49), 7-5 | Fenway Park (2-2) | 46-47 | |
| » Starters: Dave Wickersham vs Bill Monbouquette | Sixth | 10½ out |
| Wednesday, July 22 |
| » Defeated Red Sox (46-50), 8-6 | Fenway Park (3-2) | 47-47 | |
| » Starters: Ed Rakow vs Earl Wilson | Fifth | 10½ out |
| Thursday, July 23 |
| » Lost to Red Sox (47-50), 4-3 | Fenway Park (3-3) | 47-48 | |
| » Starters: Joe Sparma vs Dave Morehead | Fifth | 10½ out |
| Friday, July 24 |
| » Defeated Yankees (55-36), 10-5 | Tiger Stadium (27-21) | 48-48 | |
| » Starters: Rollie Sheldon vs Hank Aguirre | Sixth | 11½ out |
| » Lost to Yankees (56-36), 6-3 | Tiger Stadium (27-22) | 48-49 | |
| » Starters: Whitey Ford vs Mickey Lolich | Sixth | 11½ out |
| Saturday, July 25 |
| » Lost to Yankees (57-36), 14-2 | Tiger Stadium (27-23) | 48-50 | Lost 2 |
| » Starters: Jim Bouton vs Dave Wickersham | Sixth | 12½ out |
| Future Tiger Jose Bautista is born in Bani, D.R. |
| Sunday, July 26 |
| » Lost to Yankees (58-36), 11-6 | Tiger Stadium (27-24) | 48-51 | Lost 3 |
| » Starters: Al Downing vs Ed Rakow | Seventh | 13½ out |
| » Lost to Yankees (59-36), 5-4 | Tiger Stadium (27-25) | 48-52 | Lost 4 |
| » Starters: Bud Daley vs Denny McLain | Seventh | 13½ out |
| Monday, July 27 |
| » Major-league debuts: Dave Eilers (Braves) |
| Tuesday, July 28 |
| » Defeated White Sox (59-39), 6-3 | Tiger Stadium (28-25) | 49-52 | |
| » Starters: Joe Horlen vs Mickey Lolich | Seventh | 13 out |
| Wednesday, July 29 |
| » Defeated White Sox (59-40), 3-2 | Tiger Stadium (29-25) | 50-52 | Won 2 |
| » Starters: Ray Herbert vs Hank Aguirre | Sixth | 13 out |
| Thursday, July 30 |
| » Lost to White Sox (60-40), 2-0 | Tiger Stadium (29-26) | 50-53 | |
| » Starters: Gary Peters vs Dave Wickersham | Sixth | 13½ out |
| Friday, July 31 |
| » Lost to Indians (44-57), 12-3 | Cleveland Stadium (1-3) | 50-54 | Lost 2 |
| » Starters: Ed Rakow vs Jack Kralick | Seventh | 14 out |
| » Lost to Indians (45-57), 4-2 | Cleveland Stadium (1-4) | 50-55 | Lost 3 |
| » Starters: Joe Sparma vs Pedro Ramos | Seventh | 14 out |
| Saturday, August 1 |
| » Defeated Indians (45-58), 2-1 | Cleveland Stadium (2-4) | 51-55 | |
| » Starters: Denny McLain vs Lee Stange | Seventh | 14 out |
| Sunday, August 2 |
| » Lost to Indians (46-58), 6-1 | Cleveland Stadium (2-5) | 51-56 | |
| » Starters: Hank Aguirre vs Sam McDowell | Seventh | 15½ out |
| » Lost to Indians (47-58), 2-1 | Cleveland Stadium (2-6) | 51-57 | Lost 2 |
| » Starters: Mickey Lolich vs Jack Kralick | Seventh | 15½ out |
| Tuesday, August 4 |
| » Defeated White Sox (64-41), 4-3 | Comiskey Park I (2-3) | 52-57 | |
| » Starters: Dave Wickersham vs Gary Peters | Seventh | 14½ out |
| Wednesday, August 5 |
| » Defeated White Sox (64-42), 3-1 | Comiskey Park I (3-3) | 53-57 | Won 2 |
| » Starters: Denny McLain vs Juan Pizarro | Sixth | 13½ out |
| Thursday, August 6 |
| » Defeated White Sox (64-43), 5-2 | Comiskey Park I (4-3) | 54-57 | Won 3 |
| » Starters: Mickey Lolich vs Joe Horlen | Sixth | 13½ out |
| Friday, August 7 |
| » Defeated Athletics (42-67), 5-2 | Tiger Stadium (30-26) | 55-57 | Won 4 |
| » Starters: Ted Bowsfield vs Phil Regan | Fifth | 13½ out |
| Saturday, August 8 |
| » Defeated Athletics (42-68), 4-3 | Tiger Stadium (31-26) | 56-57 | Won 5 |
| » Starters: John O'Donoghue vs Dave Wickersham | Fifth | 13½ out |
| Sunday, August 9 |
| » Defeated Athletics (42-69), 4-2 | Tiger Stadium (32-26) | 57-57 | Won 6 |
| » Starters: Orlando Pena vs Joe Sparma | Fifth | 12½ out |
| » Defeated Athletics (42-70), 5-2 | Tiger Stadium (33-26) | 58-57 | Won 7 |
| » Starters: Moe Drabowsky vs Denny McLain | Fifth | 12½ out |
| Tuesday, August 11 |
| » Lost to Twins (55-59), 5-3 | Metropolitan Stadium (4-3) | 58-58 | |
| » Starters: Hank Aguirre vs Dick Stigman | Fifth | 13½ out |
| Wednesday, August 12 |
| » Defeated Twins (55-60), 6-2 | Metropolitan Stadium (5-3) | 59-58 | |
| » Starters: Mickey Lolich vs Mudcat Grant | Fifth | 13½ out |
| Thursday, August 13 |
| » Lost to Twins (56-60), 6-3 | Metropolitan Stadium (5-4) | 59-59 | |
| » Starters: Dave Wickersham vs Camilo Pascual | Fifth | 14½ out |
| Friday, August 14 |
| » Lost to Athletics (43-72), 5-4 | Municipal Stadium (3-4) | 59-60 | Lost 2 |
| » Starters: Phil Regan vs Orlando Pena | Fifth | 15½ out |
| Saturday, August 15 |
| » Defeated Athletics (43-73), 5-1 | Municipal Stadium (4-4) | 60-60 | |
| » Starters: Denny McLain vs Diego Segui | Fifth | 14½ out |
| Sunday, August 16 |
| » Defeated Athletics (43-74), 11-5 | Municipal Stadium (5-4) | 61-60 | Won 2 |
| » Starters: Dave Wickersham vs John O'Donoghue | Fourth | 13½ out |
| Tuesday, August 18 |
| » Lost to Angels (62-60), 1-0 | Tiger Stadium (33-27) | 61-61 | |
| » Starters: Dean Chance vs Hank Aguirre | Fourth | 14 out |
| » Defeated Angels (62-61), 1-0 | Tiger Stadium (34-27) | 62-61 | |
| » Starters: Fred Newman vs Mickey Lolich | Fourth | 14 out |
| Wednesday, August 19 |
| » Defeated Angels (62-62), 5-2 | Tiger Stadium (35-27) | 63-61 | Won 2 |
| » Starters: Aubrey Gatewood vs Joe Sparma | Fourth | 13 out |
| Thursday, August 20 |
| » Lost to Angels (63-62), 4-3 | Tiger Stadium (35-28) | 63-62 | |
| » Starters: George Brunet vs Denny McLain | Fourth | 13½ out |
| Friday, August 21 |
| » Defeated Twins (61-61), 4-1 | Tiger Stadium (36-28) | 64-62 | |
| » Starters: Dick Stigman vs Dave Wickersham | Fourth | 13 out |
| Sunday, August 23 |
| » Lost to Twins (62-61), 6-5 | Tiger Stadium (36-29) | 64-63 | |
| » Starters: Camilo Pascual vs Mickey Lolich | Fourth | 13½ out |
| » Defeated Twins (62-62), 5-2 | Tiger Stadium (37-29) | 65-63 | |
| » Starters: Mudcat Grant vs Hank Aguirre | Fourth | 13½ out |
| Future Tiger Jeff Manto is born in Bristol, PA. |
| Tuesday, August 25 |
| » Defeated Red Sox (58-69), 11-6 | Fenway Park (4-3) | 66-63 | Won 2 |
| » Starters: Denny McLain vs Dave Morehead | Fourth | 12½ out |
| Wednesday, August 26 |
| » Defeated Red Sox (58-70), 4-1 | Fenway Park (5-3) | 67-63 | Won 3 |
| » Starters: Dave Wickersham vs Bob Heffner | Fourth | 11½ out |
| Future Tiger Chad Kreuter is born in Greenbrae, CA. |
| Thursday, August 27 |
| » Defeated Red Sox (58-71), 5-4 | Fenway Park (6-3) | 68-63 | Won 4 |
| » Starters: Joe Sparma vs Jack Lamabe | Fourth | 11 out |
| Friday, August 28 |
| » Defeated Angels (66-67), 12-1 | Dodger Stadium (3-3) | 69-63 | Won 5 |
| » Starters: Hank Aguirre vs Fred Newman | Fourth | 10 out |
| » Defeated Angels (66-68), 8-7 | Dodger Stadium (4-3) | 70-63 | Won 6 |
| » Starters: Phil Regan vs Dan Osinski | Fourth | 10 out |
| Saturday, August 29 |
| » Lost to Angels (67-68), 3-2 | Dodger Stadium (4-4) | 70-64 | |
| » Starters: Denny McLain vs Dean Chance | Fourth | 11 out |
| Sunday, August 30 |
| » Lost to Angels (68-68), 5-4 | Dodger Stadium (4-5) | 70-65 | Lost 2 |
| » Starters: Dave Wickersham vs Ken McBride | Fourth | 11 out |
| Former Tiger Bob Jones dies in San Diego, CA at the age of 75. |
| Tuesday, September 1 |
| » Defeated White Sox (80-55), 8-0 | Comiskey Park I (5-3) | 71-65 | |
| » Starters: Mickey Lolich vs Ray Herbert | Fourth | 10 out |
| Wednesday, September 2 |
| » Lost to White Sox (81-55), 7-0 | Comiskey Park I (5-4) | 71-66 | |
| » Starters: Hank Aguirre vs Gary Peters | Fourth | 11 out |
| Friday, September 4 |
| » Defeated Senators (53-84), 1-0 | Robert F. Kennedy Stadium (3-4) | 72-66 | |
| » Starters: Dave Wickersham vs Claude Osteen | Fourth | 10½ out |
| Saturday, September 5 |
| » Defeated Senators (53-85), 4-0 | Robert F. Kennedy Stadium (4-4) | 73-66 | Won 2 |
| » Starters: Mickey Lolich vs Buster Narum | Fourth | 10½ out |
| Sunday, September 6 |
| » Defeated Senators (53-86), 9-3 | Robert F. Kennedy Stadium (5-4) | 74-66 | Won 3 |
| » Starters: Hank Aguirre vs Frank Kreutzer | Fourth | 10 out |
| Monday, September 7 |
| » Lost to Indians (69-70), 7-2 | Cleveland Stadium (2-7) | 74-67 | |
| » Starters: Denny McLain vs Sam McDowell | Fourth | 10 out |
| Wednesday, September 9 |
| » Defeated Yankees (81-57), 4-0 | Tiger Stadium (38-29) | 75-67 | |
| » Starters: Whitey Ford vs Mickey Lolich | Fourth | 9½ out |
| Thursday, September 10 |
| » Lost to Yankees (82-57), 5-2 | Tiger Stadium (38-30) | 75-68 | |
| » Starters: Al Downing vs Hank Aguirre | Fourth | 10½ out |
| Friday, September 11 |
| » Defeated Senators (56-89), 5-4 | Tiger Stadium (39-30) | 76-68 | |
| » Starters: Dave Stenhouse vs Dave Wickersham | Fourth | 10 out |
| Saturday, September 12 |
| » Defeated Senators (56-90), 6-5 | Tiger Stadium (40-30) | 77-68 | Won 2 |
| » Starters: Bennie Daniels vs Mickey Lolich | Fourth | 10 out |
| Sunday, September 13 |
| » Lost to Senators (57-90), 5-1 | Tiger Stadium (40-31) | 77-69 | |
| » Starters: Claude Osteen vs Phil Regan | Fourth | 10 out |
| Tuesday, September 15 |
| » Lost to White Sox (87-61), 3-2 | Tiger Stadium (40-32) | 77-70 | Lost 2 |
| » Starters: Joe Horlen vs Dave Wickersham | Fourth | 10½ out |
| » Major-league debuts: Marv Staehle (White Sox) |
| Wednesday, September 16 |
| » Lost to White Sox (88-61), 4-1 | Tiger Stadium (40-33) | 77-71 | Lost 3 |
| » Starters: Gary Peters vs Mickey Lolich | Third | 10½ out |
| Friday, September 18 |
| » Lost to Indians (75-72), 3-1 | Tiger Stadium (40-34) | 77-72 | Lost 4 |
| » Starters: Jack Kralick vs Hank Aguirre | Fourth | 11½ out |
| Sunday, September 20 |
| » Defeated Indians (75-73), 6-5 | Tiger Stadium (41-34) | 78-72 | |
| » Starters: Lee Stange vs Mickey Lolich | Fourth | 12½ out |
| » Lost to Indians (76-73), 7-2 | Tiger Stadium (41-35) | 78-73 | |
| » Starters: Luis Tiant vs Dave Wickersham | Fourth | 12½ out |
| Tuesday, September 22 |
| » Defeated Orioles (90-63), 2-1 | Tiger Stadium (42-35) | 79-73 | |
| » Starters: Milt Pappas vs Hank Aguirre | Fourth | 13 out |
| Wednesday, September 23 |
| » Defeated Orioles (90-64), 10-3 | Tiger Stadium (43-35) | 80-73 | Won 2 |
| » Starters: Steve Barber vs Phil Regan | Third | 13½ out |
| Friday, September 25 |
| » Defeated Red Sox (69-86), 3-2 | Tiger Stadium (44-35) | 81-73 | Won 3 |
| » Starters: Earl Wilson vs Dave Wickersham | Third | 13½ out |
| Saturday, September 26 |
| » Defeated Red Sox (69-87), 8-6 |
