| Friday, January 17 |
| Future Red Jeff Tabaka is born in Barberton, OH. |
| Friday, January 24 |
| Future Red Rob Dibble is born in Bridgeport, CT. |
| Tuesday, February 4 |
| Former Red Fred Smith dies in Los Angeles, CA at the age of 86. |
| Friday, February 14 |
| Future Red Keith Brown is born in Flagstaff, AZ. |
| Monday, March 2 |
| Future Red Tim Layana is born in Inglewood, CA. |
| Monday, April 13 |
| » Lost to Astros (1-0), 6-3 | Crosley Field (0-1) | 0-1 | |
| » Starters: Ken Johnson vs Jim Maloney | Third | 1 out |
| » Major-league debuts: Mel Queen and Chico Ruiz (Reds) |
| Thursday, April 16 |
| » Defeated Dodgers (1-2), 5-2 | Dodger Stadium (1-0) | 1-1 | |
| » Starters: Jim O'Toole vs Bob Miller | Third | 1 out |
| Former Red Charlie Case dies in Batavia, OH at the age of 85. |
| Friday, April 17 |
| » Defeated Dodgers (1-3), 7-3 | Dodger Stadium (2-0) | 2-1 | Won 2 |
| » Starters: Joey Jay vs Pete Richert | Third | 1 out |
| Saturday, April 18 |
| » Defeated Dodgers (1-4), 3-0 | Dodger Stadium (3-0) | 3-1 | Won 3 |
| » Starters: Jim Maloney vs Sandy Koufax | First | -- |
| Sunday, April 19 |
| » Lost to Giants (4-2), 13-6 | Candlestick Park (0-1) | 3-2 | |
| » Starters: Joe Nuxhall vs Juan Marichal | Third | 1 out |
| Monday, April 20 |
| » Lost to Giants (5-2), 5-2 | Candlestick Park (0-2) | 3-3 | Lost 2 |
| » Starters: Bob Purkey vs Jack Sanford | Fifth | 1½ out |
| Tuesday, April 21 |
| » Defeated Astros (3-4), 10-5 | Colt Stadium (1-0) | 4-3 | |
| » Starters: Jim O'Toole vs Jim Owens | Fourth | 1 out |
| » Major-league debuts: Walt Williams (Astros) Bobby Klaus (Reds) |
| Wednesday, April 22 |
| » Lost to Astros (4-4), 2-0 | Colt Stadium (1-1) | 4-4 | |
| » Starters: Joey Jay vs Bob Bruce | Fifth | 1½ out |
| Thursday, April 23 |
| » Defeated Astros (4-5), 1-0 | Colt Stadium (2-1) | 5-4 | |
| » Starters: Joe Nuxhall vs Ken Johnson | Fourth | 1½ out |
| Friday, April 24 |
| » Lost to Giants (7-2), 15-5 | Crosley Field (0-2) | 5-5 | |
| » Starters: Juan Marichal vs John Tsitouris | Sixth | 2½ out |
| » Major-league debuts: Billy McCool (Reds) Gil Garrido (Giants) |
| Saturday, April 25 |
| » Defeated Giants (7-3), 3-1 | Crosley Field (1-2) | 6-5 | |
| » Starters: Jack Sanford vs Jim Maloney | Fifth | 1½ out |
| Tuesday, April 28 |
| » Lost to Phillies (8-2), 4-2 | Crosley Field (1-3) | 6-6 | |
| » Starters: Art Mahaffey vs Jim O'Toole | Fifth | 3 out |
| Future Red Barry Larkin is born in Cincinnati, OH. |
| Thursday, April 30 |
| » Lost to Phillies (9-2), 3-1 | Crosley Field (1-4) | 6-7 | Lost 2 |
| » Starters: Dennis Bennett vs Joe Nuxhall | Sixth | 4 out |
| Friday, May 1 |
| » Defeated Mets (2-11), 4-3 | Crosley Field (2-4) | 7-7 | |
| » Starters: Tracy Stallard vs Joey Jay | Fifth | 4 out |
| Saturday, May 2 |
| » Lost to Mets (3-11), 3-0 | Crosley Field (2-5) | 7-8 | |
| » Starters: Al Jackson vs Jim Maloney | Sixth | 4 out |
| Sunday, May 3 |
| » Defeated Mets (3-12), 6-5 | Crosley Field (3-5) | 8-8 | |
| » Starters: Jack Fisher vs Bob Purkey | Fourth | 2½ out |
| » Defeated Mets (3-13), 6-3 | Crosley Field (4-5) | 9-8 | Won 2 |
| » Starters: Jay Hook vs John Tsitouris | Fourth | 2½ out |
| Monday, May 4 |
| » Lost to Pirates (10-7), 4-2 | Crosley Field (4-6) | 9-9 | |
| » Starters: Joe Gibbon vs Joey Jay | Sixth | 3½ out |
| Tuesday, May 5 |
| » Defeated Pirates (10-8), 5-4 | Crosley Field (5-6) | 10-9 | |
| » Starters: Vern Law vs Joe Nuxhall | Sixth | 3½ out |
| Wednesday, May 6 |
| » Defeated Mets (3-16), 12-4 | Shea Stadium (1-0) | 11-9 | Won 2 |
| » Starters: Sammy Ellis vs Bill Wakefield | Fifth | 2½ out |
| Thursday, May 7 |
| » Lost to Mets (4-16), 3-2 | Shea Stadium (1-1) | 11-10 | |
| » Starters: Jim Maloney vs Al Jackson | Sixth | 3½ out |
| Friday, May 8 |
| » Lost to Phillies (13-6), 11-3 | Shibe Park (0-1) | 11-11 | Lost 2 |
| » Starters: John Tsitouris vs Dennis Bennett | Sixth | 4½ out |
| Saturday, May 9 |
| » Lost to Phillies (14-6), 5-4 | Shibe Park (0-2) | 11-12 | Lost 3 |
| » Starters: Bob Purkey vs Jim Bunning | Sixth | 5½ out |
| Sunday, May 10 |
| » Defeated Phillies (14-7), 2-0 | Shibe Park (1-2) | 12-12 | |
| » Starters: Joe Nuxhall vs Chris Short | Sixth | 4½ out |
| Monday, May 11 |
| » Defeated Pirates (13-12), 7-6 | Forbes Field (1-0) | 13-12 | Won 2 |
| » Starters: Sammy Ellis vs Bob Veale | Fifth | 3½ out |
| Tuesday, May 12 |
| » Lost to Pirates (14-12), 3-2 | Forbes Field (1-1) | 13-13 | |
| » Starters: Jim Maloney vs Joe Gibbon | Sixth | 4½ out |
| Thursday, May 14 |
| Former Red Dave Altizer dies in Pleasant Hill, IL at the age of 88. |
| Friday, May 15 |
| » Defeated Cubs (10-14), 10-5 | Wrigley Field (1-0) | 14-13 | |
| » Starters: Bob Purkey vs Larry Jackson | Fifth | 3 out |
| Saturday, May 16 |
| » Defeated Cubs (10-15), 5-2 | Wrigley Field (2-0) | 15-13 | Won 2 |
| » Starters: Joe Nuxhall vs Glen Hobbie | Fourth | 2½ out |
| Sunday, May 17 |
| » Lost to Cubs (11-15), 5-4 | Wrigley Field (2-1) | 15-14 | |
| » Starters: Jim O'Toole vs Bob Buhl | Fourth | 3½ out |
| » Defeated Cubs (11-16), 7-1 | Wrigley Field (3-1) | 16-14 | |
| » Starters: Jim Maloney vs Paul Toth | Fourth | 3½ out |
| Tuesday, May 19 |
| » Lost to Braves (17-15), 4-2 | Crosley Field (5-7) | 16-15 | |
| » Starters: Warren Spahn vs Sammy Ellis | Fifth | 4 out |
| Wednesday, May 20 |
| » Lost to Braves (18-15), 7-3 | Crosley Field (5-8) | 16-16 | Lost 2 |
| » Starters: Denny Lemaster vs Bob Purkey | Fifth | 4 out |
| Friday, May 22 |
| » Lost to Cubs (13-18), 9-1 | Crosley Field (5-9) | 16-17 | Lost 3 |
| » Starters: Bob Buhl vs Joe Nuxhall | Sixth | 5½ out |
| Saturday, May 23 |
| » Lost to Cubs (14-18), 5-3 | Crosley Field (5-10) | 16-18 | Lost 4 |
| » Starters: Dick Ellsworth vs Jim Maloney | Sixth | 5½ out |
| Future Red Gino Minutelli is born in Wilmington, DE. |
| Sunday, May 24 |
| » Defeated Cubs (14-19), 6-5 | Crosley Field (6-10) | 17-18 | |
| » Starters: Larry Jackson vs Jim O'Toole | Sixth | 4 out |
| » Defeated Cubs (14-20), 12-4 | Crosley Field (7-10) | 18-18 | Won 2 |
| » Starters: Paul Toth vs Sammy Ellis | Sixth | 4 out |
| Tuesday, May 26 |
| » Defeated Dodgers (18-22), 6-2 | Crosley Field (8-10) | 19-18 | Won 3 |
| » Starters: Don Drysdale vs Bob Purkey | Fifth | 3 out |
| Wednesday, May 27 |
| » Defeated Dodgers (18-23), 1-0 | Crosley Field (9-10) | 20-18 | Won 4 |
| » Starters: Sandy Koufax vs Joe Nuxhall | Fifth | 3 out |
| Thursday, May 28 |
| » Tied Dodgers, 2-2 | Crosley Field (9-10) | 20-18 | |
| » Starters: Phil Ortega vs Jim Maloney | Sixth | 3½ out |
| Friday, May 29 |
| » Lost to Cardinals (23-19), 4-3 | Sportsman's Park III (0-1) | 20-19 | |
| » Starters: Jim O'Toole vs Ray Sadecki | Fifth | 3½ out |
| Saturday, May 30 |
| » Lost to Cardinals (24-19), 7-1 | Sportsman's Park III (0-2) | 20-20 | Lost 2 |
| » Starters: Sammy Ellis vs Ernie Broglio | Fifth | 4½ out |
| Sunday, May 31 |
| » Defeated Cardinals (24-20), 6-0 | Sportsman's Park III (1-2) | 21-20 | |
| » Starters: Bob Purkey vs Ray Washburn | Fifth | 5 out |
| » Lost to Cardinals (25-20), 2-1 | Sportsman's Park III (1-3) | 21-21 | |
| » Starters: John Tsitouris vs Bob Gibson | Fifth | 5 out |
| Tuesday, June 2 |
| » Defeated Braves (23-22), 7-5 | County Stadium (1-0) | 22-21 | |
| » Starters: Joe Nuxhall vs Warren Spahn | Fifth | 5 out |
| Wednesday, June 3 |
| » Lost to Braves (24-22), 3-2 | County Stadium (1-1) | 22-22 | |
| » Starters: Jim Maloney vs Denny Lemaster | Fifth | 6 out |
| Thursday, June 4 |
| » Defeated Braves (24-23), 6-3 | County Stadium (2-1) | 23-22 | |
| » Starters: Jim O'Toole vs Tony Cloninger | Sixth | 5 out |
| Friday, June 5 |
| » Defeated Cardinals (26-23), 5-4 | Crosley Field (10-10) | 24-22 | Won 2 |
| » Starters: Glen Hobbie vs Bob Purkey | Fifth | 4 out |
| Saturday, June 6 |
| » Defeated Cardinals (26-24), 3-0 | Crosley Field (11-10) | 25-22 | Won 3 |
| » Starters: Ray Washburn vs John Tsitouris | Fourth | 3½ out |
| Sunday, June 7 |
| » Defeated Cardinals (26-25), 11-6 | Crosley Field (12-10) | 26-22 | Won 4 |
| » Starters: Curt Simmons vs Joe Nuxhall | Third | 3½ out |
| Monday, June 8 |
| » Lost to Dodgers (25-26), 2-1 | Dodger Stadium (3-1) | 26-23 | |
| » Starters: Jim Maloney vs Sandy Koufax | Fourth | 4 out |
| Tuesday, June 9 |
| » Defeated Dodgers (25-27), 2-1 | Dodger Stadium (4-1) | 27-23 | |
| » Starters: Jim O'Toole vs Joe Moeller | Third | 3 out |
| Wednesday, June 10 |
| » Defeated Dodgers (25-28), 5-4 | Dodger Stadium (5-1) | 28-23 | Won 2 |
| » Starters: Bob Purkey vs Phil Ortega | Third | 2½ out |
| Thursday, June 11 |
| » Lost to Astros (26-30), 5-3 | Colt Stadium (2-2) | 28-24 | |
| » Starters: John Tsitouris vs Bob Bruce | Third | 2½ out |
| Friday, June 12 |
| » Defeated Astros (26-31), 3-0 | Colt Stadium (3-2) | 29-24 | |
| » Starters: Joe Nuxhall vs Ken Johnson | Third | 1½ out |
| Saturday, June 13 |
| » Defeated Astros (26-32), 6-1 | Colt Stadium (4-2) | 30-24 | Won 2 |
| » Starters: Jim Maloney vs Hal Brown | Third | 1½ out |
| Sunday, June 14 |
| » Lost to Giants (33-23), 8-2 | Candlestick Park (0-3) | 30-25 | |
| » Starters: Jim O'Toole vs Ron Herbel | Third | 3 out |
| Monday, June 15 |
| » Lost to Giants (34-23), 6-5 | Candlestick Park (0-4) | 30-26 | Lost 2 |
| » Starters: Bob Purkey vs Bob Hendley | Third | 3½ out |
| Tuesday, June 16 |
| » Defeated Giants (34-24), 9-4 | Candlestick Park (1-4) | 31-26 | |
| » Starters: John Tsitouris vs Jack Sanford | Third | 3½ out |
| Wednesday, June 17 |
| » Lost to Giants (35-24), 3-2 | Candlestick Park (1-5) | 31-27 | |
| » Starters: Joe Nuxhall vs Bobby Bolin | Third | 3½ out |
| Friday, June 19 |
| » Defeated Dodgers (30-31), 11-1 | Crosley Field (13-10) | 32-27 | |
| » Starters: Joe Moeller vs Jim Maloney | Third | 4½ out |
| Saturday, June 20 |
| » Defeated Dodgers (30-32), 6-4 | Crosley Field (14-10) | 33-27 | Won 2 |
| » Starters: Don Drysdale vs Jim O'Toole | Third | 3½ out |
| Sunday, June 21 |
| » Lost to Dodgers (31-32), 4-2 | Crosley Field (14-11) | 33-28 | |
| » Starters: Sandy Koufax vs Bob Purkey | Third | 4½ out |
| » Defeated Dodgers (31-33), 2-1 | Crosley Field (15-11) | 34-28 | |
| » Starters: Larry Miller vs Joey Jay | Third | 4½ out |
| » Major-league debuts: Larry Miller (Dodgers) |
| Monday, June 22 |
| » Lost to Giants (38-26), 6-2 | Crosley Field (15-12) | 34-29 | |
| » Starters: Bobby Bolin vs John Tsitouris | Third | 5 out |
| Tuesday, June 23 |
| » Lost to Giants (39-26), 4-0 | Crosley Field (15-13) | 34-30 | Lost 2 |
| » Starters: Juan Marichal vs Jim Maloney | Fourth | 5 out |
| » Defeated Giants (39-27), 5-4 | Crosley Field (16-13) | 35-30 | |
| » Starters: Billy O'Dell vs Joe Nuxhall | Fourth | 5 out |
| Wednesday, June 24 |
| » Lost to Giants (40-27), 2-1 | Crosley Field (16-14) | 35-31 | |
| » Starters: Ron Herbel vs Jim O'Toole | Fourth | 6 out |
| Friday, June 26 |
| » Lost to Pirates (37-29), 8-3 | Forbes Field (1-2) | 35-32 | Lost 2 |
| » Starters: Joey Jay vs Bob Veale | Fourth | 7 out |
| Saturday, June 27 |
| » Lost to Pirates (38-29), 4-2 | Forbes Field (1-3) | 35-33 | Lost 3 |
| » Starters: Bob Purkey vs Steve Blass | Fourth | 7 out |
| Sunday, June 28 |
| » Defeated Pirates (38-30), 6-2 | Forbes Field (2-3) | 36-33 | |
| » Starters: John Tsitouris vs Vern Law | Fourth | 6½ out |
| » Defeated Pirates (38-31), 6-5 | Forbes Field (3-3) | 37-33 | Won 2 |
| » Starters: Jim Maloney vs Bob Friend | Fourth | 6½ out |
| Monday, June 29 |
| » Defeated Cubs (34-34), 6-1 | Wrigley Field (4-1) | 38-33 | Won 3 |
| » Starters: Jim O'Toole vs Lew Burdette | Fourth | 5½ out |
| Tuesday, June 30 |
| » Lost to Cubs (35-34), 1-0 | Wrigley Field (4-2) | 38-34 | |
| » Starters: Joey Jay vs Larry Jackson | Fourth | 6½ out |
| Wednesday, July 1 |
| » Defeated Cubs (35-35), 6-5 | Crosley Field (17-14) | 39-34 | |
| » Starters: Dick Ellsworth vs Bob Purkey | Fourth | 6½ out |
| Thursday, July 2 |
| » Defeated Cubs (35-36), 7-0 | Crosley Field (18-14) | 40-34 | Won 2 |
| » Starters: Ernie Broglio vs Jim Maloney | Third | 6½ out |
| Friday, July 3 |
| » Defeated Cardinals (38-39), 4-1 | Crosley Field (19-14) | 41-34 | Won 3 |
| » Starters: Bob Gibson vs John Tsitouris | Third | 5½ out |
| Saturday, July 4 |
| » Defeated Cardinals (38-40), 3-2 | Crosley Field (20-14) | 42-34 | Won 4 |
| » Starters: Mike Cuellar vs Jim O'Toole | Third | 5 out |
| Sunday, July 5 |
| » Lost to Cardinals (39-40), 3-1 | Crosley Field (20-15) | 42-35 | |
| » Starters: Roger Craig vs Joey Jay | Third | 6 out |
| Wednesday, July 8 |
| » Lost to Pirates (41-35), 9-1 | Forbes Field (3-4) | 42-36 | Lost 2 |
| » Starters: Jim Maloney vs Bob Veale | Fourth | 6½ out |
| Thursday, July 9 |
| » Lost to Phillies (48-28), 4-3 | Shibe Park (1-3) | 42-37 | Lost 3 |
| » Starters: John Tsitouris vs Ray Culp | Third | 7½ out |
| Friday, July 10 |
| » Defeated Phillies (48-29), 5-1 | Shibe Park (2-3) | 43-37 | |
| » Starters: Jim O'Toole vs Dennis Bennett | Third | 6½ out |
| Saturday, July 11 |
| » Defeated Phillies (48-30), 3-1 | Shibe Park (3-3) | 44-37 | Won 2 |
| » Starters: Joe Nuxhall vs Jim Bunning | Third | 5½ out |
| Sunday, July 12 |
| » Lost to Mets (25-60), 1-0 | Shea Stadium (1-2) | 44-38 | |
| » Starters: Joey Jay vs Galen Cisco | Fourth | 6½ out |
| » Lost to Mets (26-60), 5-1 | Shea Stadium (1-3) | 44-39 | Lost 2 |
| » Starters: Bob Purkey vs Frank Lary | Fourth | 6½ out |
| Tuesday, July 14 |
| » Defeated Astros (39-47), 6-5 | Crosley Field (21-15) | 45-39 | |
| » Starters: Larry Yellen vs John Tsitouris | Third | 5½ out |
| » Defeated Astros (39-48), 10-3 | Crosley Field (22-15) | 46-39 | Won 2 |
| » Starters: Ken Johnson vs Jim Maloney | Third | 5½ out |
| Wednesday, July 15 |
| » Defeated Astros (39-49), 2-1 | Crosley Field (23-15) | 47-39 | Won 3 |
| » Starters: Turk Farrell vs Jim O'Toole | Third | 4½ out |
| Thursday, July 16 |
| » Defeated Astros (39-50), 3-2 | Crosley Field (24-15) | 48-39 | Won 4 |
| » Starters: Don Nottebart vs Joe Nuxhall | Third | 3½ out |
| Friday, July 17 |
| » Lost to Phillies (51-34), 5-4 | Crosley Field (24-16) | 48-40 | |
| » Starters: Chris Short vs Joey Jay | Third | 4½ out |
| Saturday, July 18 |
| » Defeated Phillies (51-35), 14-4 | Crosley Field (25-16) | 49-40 | |
| » Starters: Ray Culp vs John Tsitouris | Third | 3½ out |
| Sunday, July 19 |
| » Defeated Phillies (51-36), 7-4 | Crosley Field (26-16) | 50-40 | Won 2 |
| » Starters: Jim Bunning vs Jim Maloney | Third | 3½ out |
| » Lost to Phillies (52-36), 4-3 | Crosley Field (26-17) | 50-41 | |
| » Starters: John Boozer vs Jim O'Toole | Third | 3½ out |
| Monday, July 20 |
| » Defeated Phillies (52-37), 6-2 | Crosley Field (27-17) | 51-41 | |
| » Starters: Dennis Bennett vs Joe Nuxhall | Third | 2½ out |
| Tuesday, July 21 |
| » Lost to Mets (28-66), 4-2 | Crosley Field (27-18) | 51-42 | |
| » Starters: Tracy Stallard vs Joey Jay | Third | 3½ out |
| Wednesday, July 22 |
| » Lost to Mets (29-66), 4-3 | Crosley Field (27-19) | 51-43 | Lost 2 |
| » Starters: Al Jackson vs John Tsitouris | Third | 4½ out |
| Thursday, July 23 |
| » Defeated Mets (29-67), 5-4 | Crosley Field (28-19) | 52-43 | |
| » Starters: Darrell Sutherland vs Jim Maloney | Third | 4½ out |
| Friday, July 24 |
| » Defeated Pirates (48-43), 2-0 | Crosley Field (29-19) | 53-43 | Won 2 |
| » Starters: Bob Friend vs Jim O'Toole | Third | 4½ out |
| Saturday, July 25 |
| » Lost to Pirates (49-43), 6-3 | Crosley Field (29-20) | 53-44 | |
| » Starters: Vern Law vs Joe Nuxhall | Third | 4½ out |
| Sunday, July 26 |
| » Defeated Pirates (49-44), 7-2 | Crosley Field (30-20) | 54-44 | |
| » Starters: Joe Gibbon vs Joey Jay | Third | 3½ out |
| » Lost to Pirates (50-44), 5-1 | Crosley Field (30-21) | 54-45 | |
| » Starters: Bob Veale vs John Tsitouris | Third | 3½ out |
| » Major-league debuts: Tony Perez (Reds) |
| Monday, July 27 |
| » Defeated Braves (50-48), 11-2 | County Stadium (3-1) | 55-45 | |
| » Manager: Dick Sisler |
| » Starters: Jim Maloney vs Denny Lemaster | Third | 3 out |
| » Major-league debuts: Dave Eilers (Braves) |
| Tuesday, July 28 |
| » Lost to Braves (51-48), 3-2 | County Stadium (3-2) | 55-46 | |
| » Starters: Jim O'Toole vs Hank Fischer | Third | 4 out |
| Wednesday, July 29 |
| » Lost to Braves (52-48), 6-2 | County Stadium (3-3) | 55-47 | Lost 2 |
| » Starters: Joe Nuxhall vs Tony Cloninger | Third | 4 out |
| Friday, July 31 |
| » Defeated Cardinals (53-49), 7-6 | Sportsman's Park III (2-3) | 56-47 | |
| » Starters: John Tsitouris vs Gordie Richardson | Third | 4½ out |
| Saturday, August 1 |
| » Defeated Cardinals (53-50), 6-5 | Sportsman's Park III (3-3) | 57-47 | Won 2 |
| » Starters: Joey Jay vs Bob Gibson | Third | 4½ out |
| Sunday, August 2 |
| » Lost to Cardinals (54-50), 5-4 | Sportsman's Park III (3-4) | 57-48 | |
| » Starters: Jim Maloney vs Curt Simmons | Third | 4½ out |
| Tuesday, August 4 |
| » Defeated Braves (54-50), 5-2 | Crosley Field (31-21) | 58-48 | |
| » Manager: Fred Hutchinson |
| » Starters: Tony Cloninger vs Bob Purkey | Third | 3½ out |
| » Defeated Braves (54-51), 4-2 | Crosley Field (32-21) | 59-48 | Won 2 |
| » Starters: Bob Sadowski vs Jim O'Toole | Third | 3½ out |
| Wednesday, August 5 |
| » Lost to Braves (55-51), 6-3 | Crosley Field (32-22) | 59-49 | |
| » Starters: Denny Lemaster vs John Tsitouris | Third | 5 out |
| Thursday, August 6 |
| » Defeated Braves (55-52), 9-3 | Crosley Field (33-22) | 60-49 | |
| » Starters: Hank Fischer vs Joey Jay | Third | 4 out |
| Friday, August 7 |
| » Defeated Giants (62-47), 5-3 | Crosley Field (34-22) | 61-49 | Won 2 |
| » Starters: Bob Hendley vs Jim Maloney | Third | 4 out |
| Saturday, August 8 |
| » Lost to Giants (63-47), 1-0 | Crosley Field (34-23) | 61-50 | |
| » Starters: Gaylord Perry vs Joe Nuxhall | Third | 5 out |
| Sunday, August 9 |
| » Lost to Giants (64-47), 7-5 | Crosley Field (34-24) | 61-51 | Lost 2 |
| » Starters: Bobby Bolin vs John Tsitouris | Third | 6 out |
| Monday, August 10 |
| » Defeated Dodgers (55-55), 7-2 | Crosley Field (35-24) | 62-51 | |
| » Starters: Joe Moeller vs Bob Purkey | Third | 5½ out |
| Tuesday, August 11 |
| » Defeated Dodgers (55-56), 4-2 | Crosley Field (36-24) | 63-51 | Won 2 |
| » Starters: Phil Ortega vs Joey Jay | Third | 5½ out |
| Wednesday, August 12 |
| » Lost to Dodgers (56-56), 4-1 | Crosley Field (36-25) | 63-52 | |
| » Starters: Sandy Koufax vs Jim O'Toole | Third | 6½ out |
| Friday, August 14 |
| » Lost to Astros (49-68), 3-2 | Colt Stadium (4-3) | 63-53 | Lost 2 |
| » Manager: Dick Sisler |
| » Starters: Jim Maloney vs Bob Bruce | Third | 7½ out |
| Saturday, August 15 |
| » Lost to Astros (50-68), 7-4 | Colt Stadium (4-4) | 63-54 | Lost 3 |
| » Starters: Joe Nuxhall vs Don Nottebart | Fourth | 8½ out |
| Sunday, August 16 |
| » Defeated Astros (50-69), 8-3 | Colt Stadium (5-4) | 64-54 | |
| » Starters: Joey Jay vs Ken Johnson | Fourth | 7½ out |
| Future Red Rick Reed is born in Huntington, WV. |
| Tuesday, August 18 |
| » Defeated Giants (67-52), 1-0 | Candlestick Park (2-5) | 65-54 | Won 2 |
| » Starters: Jim O'Toole vs Bobby Bolin | Third | 7 out |
| Wednesday, August 19 |
| » Defeated Giants (67-53), 7-1 | Candlestick Park (3-5) | 66-54 | Won 3 |
| » Starters: Bob Purkey vs Ron Herbel | Third | 7 out |
| Thursday, August 20 |
| » Defeated Giants (67-54), 10-7 | Candlestick Park (4-5) | 67-54 | Won 4 |
| » Starters: Joe Nuxhall vs Gaylord Perry | Second | 7½ out |
| Friday, August 21 |
| » Defeated Dodgers (59-61), 3-2 | Dodger Stadium (6-1) | 68-54 | Won 5 |
| » Starters: Jim Maloney vs Larry Miller | Second | 7½ out |
| Saturday, August 22 |
| » Defeated Dodgers (59-62), 2-1 | Dodger Stadium (7-1) | 69-54 | Won 6 |
| » Starters: Joey Jay vs Don Drysdale | Second | 6½ out |
| Sunday, August 23 |
| » Lost to Dodgers (60-62), 1-0 | Dodger Stadium (7-2) | 69-55 | |
| » Starters: Jim O'Toole vs Phil Ortega | Second | 7½ out |
| Monday, August 24 |
| Future Red Kip Gross is born in Scottsbluff, NE. |
| Tuesday, August 25 |
| » Defeated Mets (42-84), 7-2 | Crosley Field (37-25) | 70-55 | |
| » Starters: Al Jackson vs Bob Purkey | Second | 6 out |
| Wednesday, August 26 |
| » Lost to Mets (43-84), 3-1 | Crosley Field (37-26) | 70-56 | |
| » Starters: Tracy Stallard vs Joey Jay | Second | 7 out |
| Saturday, August 29 |
| » Defeated Astros (56-73), 2-1 | Crosley Field (38-26) | 71-56 | |
| » Starters: Don Larsen vs John Tsitouris | Second | 6 out |
| » Defeated Astros (56-74), 8-7 | Crosley Field (39-26) | 72-56 | Won 2 |
| » Starters: Don Nottebart vs Jim O'Toole | Second | 6 out |
| Sunday, August 30 |
| » Lost to Astros (57-74), 8-5 | Crosley Field (39-27) | 72-57 | |
| » Starters: Bob Bruce vs Bob Purkey | Second | 5½ out |
| » Defeated Astros (57-75), 7-6 | Crosley Field (40-27) | 73-57 | |
| » Starters: Ken Johnson vs Joey Jay | Second | 5½ out |
| Tuesday, September 1 |
| » Defeated Cubs (60-71), 2-1 | Crosley Field (41-27) | 74-57 | Won 2 |
| » Starters: Ernie Broglio vs Jim Maloney | Second | 5½ out |
| Wednesday, September 2 |
| » Defeated Cubs (60-72), 1-0 | Crosley Field (42-27) | 75-57 | Won 3 |
| » Starters: Bob Buhl vs Jim O'Toole | Second | 5½ out |
| Thursday, September 3 |
| » Lost to Cubs (61-72), 3-0 | Crosley Field (42-28) | 75-58 | |
| » Starters: Lew Burdette vs John Tsitouris | Second | 5½ out |
| Friday, September 4 |
| » Lost to Braves (68-66), 2-0 | Crosley Field (42-29) | 75-59 | Lost 2 |
| » Starters: Tony Cloninger vs Joey Jay | Second | 6½ out |
| Saturday, September 5 |
| » Defeated Braves (68-67), 5-1 | Crosley Field (43-29) | 76-59 | |
| » Starters: Bob Sadowski vs Bob Purkey | Second | 6½ out |
| Sunday, September 6 |
| » Defeated Braves (68-68), 6-3 | Crosley Field (44-29) | 77-59 | Won 2 |
| » Starters: Denny Lemaster vs Jim Maloney | Second | 5½ out |
| Monday, September 7 |
| » Lost to Cardinals (76-61), 3-2 | Sportsman's Park III (3-5) | 77-60 | |
| » Starters: Jim O'Toole vs Bob Gibson | Second | 6½ out |
| » Lost to Cardinals (77-61), 3-2 | Sportsman's Park III (3-6) | 77-61 | Lost 2 |
| » Starters: John Tsitouris vs Roger Craig | Second | 6½ out |
| Wednesday, September 9 |
| » Lost to Pirates (71-67), 4-1 | Forbes Field (3-5) | 77-62 | Lost 3 |
| » Starters: Joey Jay vs Bob Veale | Third | 6 out |
| Thursday, September 10 |
| » Defeated Pirates (71-68), 3-0 | Forbes Field (4-5) | 78-62 | |
| » Starters: Bob Purkey vs Bob Friend | Second | 6 out |
| Friday, September 11 |
| » Lost to Braves (73-68), 1-0 | County Stadium (3-4) | 78-63 | |
| » Starters: Jim Maloney vs Denny Lemaster | Third | 7 out |
| Saturday, September 12 |
| » Lost to Braves (74-68), 8-2 | County Stadium (3-5) | 78-64 | Lost 2 |
| » Starters: Jim O'Toole vs Hank Fischer | Fourth | 7 out |
| Sunday, September 13 |
| » Defeated Braves (74-69), 9-2 | County Stadium (4-5) | 79-64 | |
| » Starters: Joey Jay vs Warren Spahn | Fourth | 7 out |
| Tuesday, September 15 |
| » Lost to Cubs (66-78), 6-1 | Wrigley Field (4-3) | 79-65 | |
| » Starters: Bob Purkey vs Larry Jackson | Fourth | 8½ out |
| Wednesday, September 16 |
| » Defeated Cubs (66-79), 5-3 | Wrigley Field (5-3) | 80-65 | |
| » Starters: Jim Maloney vs Bob Buhl | Third | 7½ out |
| Thursday, September 17 |
| » Defeated Cubs (66-80), 7-5 | Wrigley Field (6-3) | 81-65 | Won 2 |
| » Starters: Jim O'Toole vs Lew Burdette | Third | 7½ out |
| Saturday, September 19 |
| » Defeated Cardinals (82-65), 7-5 | Crosley Field (45-29) | 82-65 | Won 3 |
| » Starters: Bob Gibson vs Bob Purkey | Third | 6½ out |
| » Lost to Cardinals (83-65), 2-0 | Crosley Field (45-30) | 82-66 | |
| » Starters: Ray Sadecki vs Billy McCool | Third | 6½ out |
| Sunday, September 20 |
| » Defeated Cardinals (83-66), 9-6 | Crosley Field (46-30) | 83-66 | |
| » Starters: Gordie Richardson vs Joe Nuxhall | Second | 6½ out |
| Monday, September 21 |
| » Defeated Phillies (90-61), 1-0 | Shibe Park (4-3) | 84-66 | Won 2 |
| » Starters: John Tsitouris vs Art Mahaffey | Second | 5½ out |
| Tuesday, September 22 |
| » Defeated Phillies (90-62), 9-2 | Shibe Park (5-3) | 85-66 | Won 3 |
| » Starters: Jim O'Toole vs Chris Short | Second | 4½ out |
| Wednesday, September 23 |
| » Defeated Phillies (90-63), 6-4 | Shibe Park (6-3) | 86-66 | Won 4 |
| » Starters: Billy McCool vs Dennis Bennett | Second | 3½ out |
| » Major-league debuts: Tommy Helms (Reds) |
| Friday, September 25 |
| » Defeated Mets (51-101), 3-0 | Shea Stadium (2-3) | 87-66 | Won 5 |
| » Starters: Jim Maloney vs Al Jackson | Second | 1½ out |
| » Defeated Mets (51-102), 4-1 | Shea Stadium (3-3) | 88-66 | Won 6 |
| » Starters: Bob Purkey vs Jack Fisher | Second | 1½ out |
| Saturday, September 26 |
| » Defeated Mets (51-103), 6-1 | Shea Stadium (4-3) | 89-66 | Won 7 |
| » Starters: John Tsitouris vs Dennis Ribant | Second | ½ out |
| Future Red Dave Martinez is born in New York, NY. |
| Sunday, September 27 |
| » Defeated Mets (51-104), 4-1 | Shea Stadium (5-3) | 90-66 | Won 8 |
