| Wednesday, January 10 |
| Future Tiger Jim Lindeman is born in Evanston, IL. |
| Friday, January 26 |
| Future Tiger Rick Schu is born in Philadelphia, PA. |
| Friday, February 16 |
| Future Tiger Dwayne Henry is born in Elkton, MD. |
| Tuesday, February 27 |
| Future Tiger Greg Cadaret is born in Detroit, MI. |
| Saturday, March 17 |
| Former Tiger Billy Purtell dies in Bradenton, FL at the age of 77. |
| Thursday, March 29 |
| Future Tiger Billy Beane is born in Orlando, FL. |
| Monday, April 9 |
| » Lost to Senators (1-0), 4-1 | Robert F. Kennedy Stadium (0-1) | 0-1 | |
| » Starters: Don Mossi vs Bennie Daniels | Third | 1 out |
| Tuesday, April 10 |
| » Major-league debuts: Howie Goss (Pirates) |
| Thursday, April 12 |
| » Major-league debuts: Larry Burright and Joe Moeller Pete Richert and Dick Tracewski (Dodgers) |
| Friday, April 13 |
| » Defeated Yankees (1-1), 5-3 | Tiger Stadium (1-0) | 1-1 | |
| » Starters: Bill Stafford vs Frank Lary | Third | 1 out |
| » Major-league debuts: Phil Linz (Yankees) |
| Saturday, April 14 |
| » Lost to Yankees (2-1), 11-5 | Tiger Stadium (1-1) | 1-2 | |
| » Starters: Ralph Terry vs Phil Regan | Fifth | 1 out |
| Sunday, April 15 |
| » Major-league debuts: Dick Phillips (Giants) |
| Tuesday, April 17 |
| » Defeated Senators (2-2), 9-2 | Tiger Stadium (2-1) | 2-2 | |
| » Starters: Bennie Daniels vs Jim Bunning | Fourth | 1 out |
| » Major-league debuts: Jim Hannan (Senators) |
| Wednesday, April 18 |
| » Defeated Senators (2-3), 5-1 | Tiger Stadium (3-1) | 3-2 | Won 2 |
| » Starters: Joe McClain vs Don Mossi | Third | 1 out |
| » Major-league debuts: Dave Stenhouse (Senators) |
| Thursday, April 19 |
| » Lost to Red Sox (3-4), 9-5 | Fenway Park (0-1) | 3-3 | |
| » Starters: Phil Regan vs Gene Conley | Fifth | 2 out |
| Saturday, April 21 |
| » Lost to Red Sox (4-4), 4-3 | Fenway Park (0-2) | 3-4 | Lost 2 |
| » Starters: Frank Lary vs Don Schwall | Seventh | 2 out |
| Sunday, April 22 |
| » Defeated Red Sox (4-5), 8-6 | Fenway Park (1-2) | 4-4 | |
| » Starters: Jim Bunning vs Bill Monbouquette | Fifth | 1 out |
| Tuesday, April 24 |
| » Defeated Athletics (7-7), 1-0 | Tiger Stadium (4-1) | 5-4 | Won 2 |
| » Starters: Dan Pfister vs Don Mossi | Third | 1 out |
| Wednesday, April 25 |
| » Lost to Athletics (8-7), 9-8 | Tiger Stadium (4-2) | 5-5 | |
| » Starters: Jerry Walker vs Doug Gallagher | Fifth | 1 out |
| Thursday, April 26 |
| » Defeated Athletics (8-8), 11-7 | Tiger Stadium (5-2) | 6-5 | |
| » Starters: John Wyatt vs Frank Lary | Third | 1 out |
| Friday, April 27 |
| » Defeated Angels (6-8), 13-4 | Tiger Stadium (6-2) | 7-5 | Won 2 |
| » Starters: Ken McBride vs Jim Bunning | Second | 1 out |
| Saturday, April 28 |
| » Lost to Angels (7-8), 7-6 | Tiger Stadium (6-3) | 7-6 | |
| » Starters: Ted Bowsfield vs Don Mossi | Fourth | 2 out |
| Sunday, April 29 |
| » Defeated Angels (7-9), 13-6 | Tiger Stadium (7-3) | 8-6 | |
| » Starters: Dean Chance vs Phil Regan | Fourth | 1½ out |
| Tuesday, May 1 |
| » Defeated Athletics (9-11), 3-2 | Municipal Stadium (1-0) | 9-6 | Won 2 |
| » Starters: Jim Bunning vs Jerry Walker | Second | 1½ out |
| Wednesday, May 2 |
| » Lost to Athletics (10-11), 12-8 | Municipal Stadium (1-1) | 9-7 | |
| » Starters: Don Mossi vs Norm Bass | Second | 2½ out |
| Thursday, May 3 |
| » Lost to Athletics (11-11), 6-4 | Municipal Stadium (1-2) | 9-8 | Lost 2 |
| » Starters: Doug Gallagher vs Ed Rakow | Fourth | 2½ out |
| Friday, May 4 |
| » Lost to Twins (12-10), 4-2 | Metropolitan Stadium (0-1) | 9-9 | Lost 3 |
| » Starters: Phil Regan vs Don Lee | Fourth | 3 out |
| Saturday, May 5 |
| » Lost to Twins (13-10), 7-2 | Metropolitan Stadium (0-2) | 9-10 | Lost 4 |
| » Starters: Jim Bunning vs Lee Stange | Ninth | 4 out |
| Future Tiger Ramon Pena is born in Santiago, D.R. |
| Sunday, May 6 |
| » Lost to Twins (14-10), 10-7 | Metropolitan Stadium (0-3) | 9-11 | Lost 5 |
| » Starters: Paul Foytack vs Camilo Pascual | Ninth | 4½ out |
| Tuesday, May 8 |
| » Defeated Angels (11-10), 10-1 | Dodger Stadium (1-0) | 10-11 | |
| » Starters: Phil Regan vs Eli Grba | Seventh | 4 out |
| Wednesday, May 9 |
| » Defeated Angels (11-11), 6-3 | Dodger Stadium (2-0) | 11-11 | Won 2 |
| » Starters: Jim Bunning vs Ted Bowsfield | Fifth | 4 out |
| Thursday, May 10 |
| » Lost to Angels (12-11), 6-4 | Dodger Stadium (2-1) | 11-12 | |
| » Starters: Jerry Casale vs Ken McBride | Seventh | 4½ out |
| Friday, May 11 |
| » Defeated Red Sox (11-13), 5-1 | Tiger Stadium (8-3) | 12-12 | |
| » Starters: Don Schwall vs Paul Foytack | Sixth | 3½ out |
| Saturday, May 12 |
| » Lost to Red Sox (12-13), 5-1 | Tiger Stadium (8-4) | 12-13 | |
| » Starters: Gene Conley vs Don Mossi | Seventh | 4½ out |
| Sunday, May 13 |
| » Defeated Red Sox (12-14), 6-5 | Tiger Stadium (9-4) | 13-13 | |
| » Starters: Galen Cisco vs Phil Regan | Sixth | 3½ out |
| Tuesday, May 15 |
| » Lost to Twins (18-13), 4-2 | Tiger Stadium (9-5) | 13-14 | |
| » Starters: Jack Kralick vs Frank Lary | Sixth | 3½ out |
| Wednesday, May 16 |
| » Lost to Twins (19-13), 8-4 | Tiger Stadium (9-6) | 13-15 | Lost 2 |
| » Starters: Camilo Pascual vs Jim Bunning | Seventh | 4½ out |
| Friday, May 18 |
| » Lost to Indians (19-11), 9-2 | Cleveland Stadium (0-1) | 13-16 | Lost 3 |
| » Starters: Paul Foytack vs Dick Donovan | Seventh | 5½ out |
| Saturday, May 19 |
| » Defeated Indians (19-12), 9-3 | Cleveland Stadium (1-1) | 14-16 | |
| » Starters: Don Mossi vs Jim Perry | Sixth | 4½ out |
| Sunday, May 20 |
| » Lost to Indians (20-12), 7-6 | Cleveland Stadium (1-2) | 14-17 | |
| » Starters: Phil Regan vs Pedro Ramos | Sixth | 4½ out |
| » Defeated Indians (20-13), 8-6 | Cleveland Stadium (2-2) | 15-17 | |
| » Starters: Frank Lary vs Sam McDowell | Sixth | 4½ out |
| Monday, May 21 |
| » Defeated White Sox (20-18), 7-3 | Comiskey Park I (1-0) | 16-17 | Won 2 |
| » Starters: Paul Foytack vs Early Wynn | Seventh | 4½ out |
| Wednesday, May 23 |
| Former Tiger Rip Radcliff dies in Enid, OK at the age of 57. |
| Thursday, May 24 |
| » Defeated Orioles (19-18), 5-4 | Memorial Stadium (1-0) | 17-17 | Won 3 |
| » Starters: Jim Bunning vs Jack Fisher | Seventh | 5 out |
| Friday, May 25 |
| » Defeated Yankees (23-14), 5-4 | Yankee Stadium (1-0) | 18-17 | Won 4 |
| » Starters: Don Mossi vs Bill Stafford | Sixth | 4 out |
| Saturday, May 26 |
| » Defeated Yankees (23-15), 2-1 | Yankee Stadium (2-0) | 19-17 | Won 5 |
| » Starters: Hank Aguirre vs Rollie Sheldon | Third | 3 out |
| Sunday, May 27 |
| » Lost to Yankees (24-15), 4-1 | Yankee Stadium (2-1) | 19-18 | |
| » Starters: Frank Lary vs Ralph Terry | Fourth | 3½ out |
| » Defeated Yankees (24-16), 5-1 | Yankee Stadium (3-1) | 20-18 | |
| » Starters: Paul Foytack vs Bob Turley | Fourth | 3½ out |
| Monday, May 28 |
| » Defeated Orioles (21-20), 5-1 | Tiger Stadium (10-6) | 21-18 | Won 2 |
| » Starters: Milt Pappas vs Jim Bunning | Third | 2½ out |
| Tuesday, May 29 |
| » Defeated Orioles (21-21), 12-4 | Tiger Stadium (11-6) | 22-18 | Won 3 |
| » Starters: Jack Fisher vs Don Mossi | Fourth | 2 out |
| Future Tiger Eric Davis is born in Los Angeles, CA. |
| Wednesday, May 30 |
| » Defeated White Sox (22-23), 7-3 | Tiger Stadium (12-6) | 23-18 | Won 4 |
| » Starters: John Buzhardt vs Phil Regan | Fourth | 2 out |
| » Lost to White Sox (23-23), 6-3 | Tiger Stadium (12-7) | 23-19 | |
| » Starters: Joe Horlen vs Sam Jones | Fourth | 2 out |
| Thursday, May 31 |
| » Defeated White Sox (23-24), 13-5 | Tiger Stadium (13-7) | 24-19 | |
| » Starters: Dom Zanni vs Paul Foytack | Fourth | 2 out |
| Friday, June 1 |
| » Lost to Indians (27-17), 7-1 | Tiger Stadium (13-8) | 24-20 | |
| » Starters: Jim Perry vs Frank Lary | Fourth | 3 out |
| Saturday, June 2 |
| » Defeated Indians (27-18), 5-3 | Tiger Stadium (14-8) | 25-20 | |
| » Starters: Dick Donovan vs Jim Bunning | Fourth | 2 out |
| Future Tiger Darnell Coles is born in San Bernardino, CA. |
| Sunday, June 3 |
| » Defeated Indians (27-19), 8-6 | Tiger Stadium (15-8) | 26-20 | Won 2 |
| » Starters: Pedro Ramos vs Don Mossi | Third | 1 out |
| Wednesday, June 6 |
| » Lost to Red Sox (20-27), 2-1 | Fenway Park (1-3) | 26-21 | |
| » Starters: Phil Regan vs Bill Monbouquette | Fourth | 1½ out |
| » Defeated Red Sox (20-28), 3-2 | Fenway Park (2-3) | 27-21 | |
| » Starters: Jim Bunning vs Gene Conley | Fourth | 1½ out |
| Thursday, June 7 |
| » Lost to Red Sox (21-28), 5-4 | Fenway Park (2-4) | 27-22 | |
| » Starters: Frank Lary vs Earl Wilson | Fourth | 2½ out |
| Friday, June 8 |
| » Defeated Senators (15-36), 7-6 | Robert F. Kennedy Stadium (1-1) | 28-22 | |
| » Starters: Paul Foytack vs Steve Hamilton | Fourth | 3 out |
| » Lost to Senators (16-36), 1-0 | Robert F. Kennedy Stadium (1-2) | 28-23 | |
| » Starters: Don Mossi vs Dave Stenhouse | Fourth | 3 out |
| Saturday, June 9 |
| » Lost to Senators (17-36), 4-2 | Robert F. Kennedy Stadium (1-3) | 28-24 | Lost 2 |
| » Starters: Hank Aguirre vs Tom Cheney | Fourth | 4 out |
| Sunday, June 10 |
| » Lost to Senators (18-36), 2-1 | Robert F. Kennedy Stadium (1-4) | 28-25 | Lost 3 |
| » Starters: Phil Regan vs Don Rudolph | Fifth | 4 out |
| » Lost to Senators (19-36), 5-4 | Robert F. Kennedy Stadium (1-5) | 28-26 | Lost 4 |
| » Starters: Jim Bunning vs Bennie Daniels | Fifth | 4 out |
| Tuesday, June 12 |
| » Lost to Yankees (32-22), 2-1 | Yankee Stadium (3-2) | 28-27 | Lost 5 |
| » Starters: Frank Lary vs Bill Stafford | Fifth | 4½ out |
| Friday, June 15 |
| » Lost to Red Sox (25-33), 3-0 | Tiger Stadium (15-9) | 28-28 | Lost 6 |
| » Starters: Gene Conley vs Don Mossi | Fifth | 4½ out |
| Saturday, June 16 |
| » Lost to Red Sox (26-33), 4-2 | Tiger Stadium (15-10) | 28-29 | Lost 7 |
| » Starters: Earl Wilson vs Jim Bunning | Seventh | 5½ out |
| Sunday, June 17 |
| » Defeated Red Sox (26-34), 8-5 | Tiger Stadium (16-10) | 29-29 | |
| » Starters: Don Schwall vs Paul Foytack | Sixth | 6½ out |
| » Lost to Red Sox (27-34), 5-0 | Tiger Stadium (16-11) | 29-30 | |
| » Starters: Ike Delock vs Phil Regan | Sixth | 6½ out |
| Tuesday, June 19 |
| » Defeated Senators (21-41), 5-0 | Tiger Stadium (17-11) | 30-30 | |
| » Starters: Claude Osteen vs Frank Lary | Sixth | 5½ out |
| Wednesday, June 20 |
| » Lost to Senators (22-41), 5-4 | Tiger Stadium (17-12) | 30-31 | |
| » Starters: Tom Cheney vs Don Mossi | Sixth | 7 out |
| Thursday, June 21 |
| » Defeated Senators (22-42), 6-3 | Tiger Stadium (18-12) | 31-31 | |
| » Starters: Don Rudolph vs Jim Bunning | Sixth | 6 out |
| Friday, June 22 |
| » Defeated Yankees (33-28), 7-5 | Tiger Stadium (19-12) | 32-31 | Won 2 |
| » Starters: Bill Stafford vs Hank Aguirre | Fifth | 6 out |
| Saturday, June 23 |
| » Lost to Yankees (34-28), 8-4 | Tiger Stadium (19-13) | 32-32 | |
| » Starters: Ralph Terry vs Phil Regan | Sixth | 5½ out |
| » Defeated Yankees (34-29), 5-4 | Tiger Stadium (20-13) | 33-32 | |
| » Starters: Rollie Sheldon vs Paul Foytack | Sixth | 5½ out |
| Sunday, June 24 |
| » Lost to Yankees (35-29), 9-7 | Tiger Stadium (20-14) | 33-33 | |
| » Starters: Bob Turley vs Frank Lary | Fifth | 6 out |
| Monday, June 25 |
| » Lost to Yankees (36-29), 2-0 | Tiger Stadium (20-15) | 33-34 | Lost 2 |
| » Starters: Whitey Ford vs Don Mossi | Seventh | 6½ out |
| Tuesday, June 26 |
| » Defeated Indians (40-29), 6-0 | Tiger Stadium (21-15) | 34-34 | |
| » Starters: Pedro Ramos vs Jim Bunning | Sixth | 6½ out |
| » Lost to Indians (41-29), 3-1 | Tiger Stadium (21-16) | 34-35 | |
| » Starters: Bob Hartman vs Sam Jones | Sixth | 6½ out |
| Wednesday, June 27 |
| » Defeated Indians (41-30), 4-0 | Tiger Stadium (22-16) | 35-35 | |
| » Starters: Dick Donovan vs Paul Foytack | Sixth | 5½ out |
| Thursday, June 28 |
| Former Tiger Mickey Cochrane dies in Lake Forest, IL at the age of 60. |
| Friday, June 29 |
| » Defeated Orioles (38-36), 1-0 | Memorial Stadium (2-0) | 36-35 | Won 2 |
| » Starters: Hank Aguirre vs Chuck Estrada | Sixth | 4½ out |
| Saturday, June 30 |
| » Lost to Orioles (39-36), 6-3 | Memorial Stadium (2-1) | 36-36 | |
| » Starters: Frank Lary vs Jack Fisher | Sixth | 4 out |
| » Defeated Orioles (39-37), 7-4 | Memorial Stadium (3-1) | 37-36 | |
| » Starters: Don Mossi vs Milt Pappas | Sixth | 4 out |
| Sunday, July 1 |
| » Defeated Orioles (39-38), 3-2 | Memorial Stadium (4-1) | 38-36 | Won 2 |
| » Starters: Jim Bunning vs Robin Roberts | Fifth | 3 out |
| Monday, July 2 |
| » Defeated White Sox (40-40), 2-1 | Tiger Stadium (23-16) | 39-36 | Won 3 |
| » Starters: Frank Baumann vs Sam Jones | Fifth | 3 out |
| Tuesday, July 3 |
| » Defeated White Sox (40-41), 5-4 | Tiger Stadium (24-16) | 40-36 | Won 4 |
| » Starters: Eddie Fisher vs Paul Foytack | Fifth | 3 out |
| Wednesday, July 4 |
| » Lost to Indians (43-34), 1-0 | Cleveland Stadium (2-3) | 40-37 | |
| » Starters: Hank Aguirre vs Jim Perry | Fifth | 4½ out |
| » Lost to Indians (44-34), 6-2 | Cleveland Stadium (2-4) | 40-38 | Lost 2 |
| » Starters: Don Mossi vs Barry Latman | Fifth | 4½ out |
| Thursday, July 5 |
| » Lost to Indians (45-34), 7-6 | Cleveland Stadium (2-5) | 40-39 | Lost 3 |
| » Starters: Frank Lary vs Pedro Ramos | Fifth | 5 out |
| Friday, July 6 |
| » Defeated Orioles (41-41), 5-4 | Tiger Stadium (25-16) | 41-39 | |
| » Starters: Robin Roberts vs Jim Bunning | Fifth | 5 out |
| Saturday, July 7 |
| » Lost to Orioles (42-41), 7-6 | Tiger Stadium (25-17) | 41-40 | |
| » Starters: Chuck Estrada vs Sam Jones | Sixth | 6 out |
| Sunday, July 8 |
| » Defeated Orioles (42-42), 5-1 | Tiger Stadium (26-17) | 42-40 | |
| » Starters: Milt Pappas vs Paul Foytack | Fifth | 5 out |
| » Defeated Orioles (42-43), 3-2 | Tiger Stadium (27-17) | 43-40 | Won 2 |
| » Starters: Steve Barber vs Hank Aguirre | Fifth | 5 out |
| Thursday, July 12 |
| » Lost to White Sox (44-45), 3-2 | Comiskey Park I (1-1) | 43-41 | |
| » Starters: Don Mossi vs Juan Pizarro | Fifth | 5 out |
| Friday, July 13 |
| » Lost to White Sox (45-45), 4-1 | Comiskey Park I (1-2) | 43-42 | Lost 2 |
| » Starters: Paul Foytack vs Ray Herbert | Fifth | 5 out |
| Saturday, July 14 |
| » Lost to White Sox (46-45), 4-2 | Comiskey Park I (1-3) | 43-43 | Lost 3 |
| » Starters: Jim Bunning vs Frank Baumann | Sixth | 6 out |
| Sunday, July 15 |
| » Lost to White Sox (47-45), 5-3 | Comiskey Park I (1-4) | 43-44 | Lost 4 |
| » Starters: Sam Jones vs Eddie Fisher | Seventh | 7½ out |
| Tuesday, July 17 |
| » Lost to Angels (49-40), 1-0 | Dodger Stadium (2-2) | 43-45 | Lost 5 |
| » Starters: Hank Aguirre vs Ken McBride | Seventh | 9 out |
| Former Tiger Sport McAllister dies in Wyandotte, MI at the age of 88. |
| Wednesday, July 18 |
| » Lost to Angels (50-40), 5-0 | Dodger Stadium (2-3) | 43-46 | Lost 6 |
| » Starters: Paul Foytack vs Don Lee | Seventh | 10 out |
| Former Tiger Carl Holling dies in Santa Rosa, CA at the age of 67. |
| Thursday, July 19 |
| » Lost to Angels (51-40), 2-1 | Dodger Stadium (2-4) | 43-47 | Lost 7 |
| » Starters: Jim Bunning vs Eli Grba | Seventh | 11 out |
| Friday, July 20 |
| » Defeated Athletics (42-54), 10-3 | Municipal Stadium (2-2) | 44-47 | |
| » Starters: Don Mossi vs Diego Segui | Seventh | 11 out |
| Saturday, July 21 |
| » Defeated Athletics (42-55), 7-5 | Municipal Stadium (3-2) | 45-47 | Won 2 |
| » Starters: Hank Aguirre vs Dan Pfister | Seventh | 11 out |
| Sunday, July 22 |
| » Lost to Athletics (43-55), 11-3 | Municipal Stadium (3-3) | 45-48 | |
| » Starters: Sam Jones vs Ed Rakow | Seventh | 10½ out |
| Monday, July 23 |
| » Lost to Twins (53-44), 8-1 | Metropolitan Stadium (0-4) | 45-49 | Lost 2 |
| » Starters: Paul Foytack vs Dick Stigman | Seventh | 11 out |
| Tuesday, July 24 |
| » Defeated Twins (53-45), 4-3 | Metropolitan Stadium (1-4) | 46-49 | |
| » Starters: Jim Bunning vs Jim Kaat | Sixth | 11 out |
| Wednesday, July 25 |
| » Lost to Twins (54-45), 7-6 | Metropolitan Stadium (1-5) | 46-50 | |
| » Starters: Don Mossi vs Jack Kralick | Sixth | 11½ out |
| Thursday, July 26 |
| Future Tiger Jody Reed is born in Tampa, FL. |
| Friday, July 27 |
| » Defeated Angels (56-43), 4-3 | Tiger Stadium (28-17) | 47-50 | |
| » Starters: Eli Grba vs Hank Aguirre | Seventh | 12 out |
| Saturday, July 28 |
| » Defeated Angels (56-44), 6-1 | Tiger Stadium (29-17) | 48-50 | Won 2 |
| » Starters: Bo Belinsky vs Paul Foytack | Seventh | 12 out |
| Sunday, July 29 |
| » Defeated Angels (56-45), 7-6 | Tiger Stadium (30-17) | 49-50 | Won 3 |
| » Starters: Ted Bowsfield vs Jim Bunning | Seventh | 12 out |
| » Lost to Angels (57-45), 12-8 | Tiger Stadium (30-18) | 49-51 | |
| » Starters: Don Lee vs Don Mossi | Seventh | 12 out |
| Wednesday, August 1 |
| » Defeated Athletics (45-60), 6-5 | Tiger Stadium (31-18) | 50-51 | |
| » Starters: Dan Pfister vs Paul Foytack | Sixth | 12½ out |
| » Defeated Athletics (45-61), 9-1 | Tiger Stadium (32-18) | 51-51 | Won 2 |
| » Starters: Jerry Walker vs Howie Koplitz | Sixth | 12½ out |
| Thursday, August 2 |
| » Lost to Athletics (46-61), 5-4 | Tiger Stadium (32-19) | 51-52 | |
| » Starters: Ed Rakow vs Hank Aguirre | Sixth | 13 out |
| Friday, August 3 |
| » Lost to Twins (60-47), 7-4 | Tiger Stadium (32-20) | 51-53 | Lost 2 |
| » Starters: Jack Kralick vs Jim Bunning | Fifth | 14 out |
| Saturday, August 4 |
| » Lost to Twins (61-47), 4-3 | Tiger Stadium (32-21) | 51-54 | Lost 3 |
| » Starters: Jackie Collum vs Don Mossi | Sixth | 14 out |
| Future Tiger John Farrell is born in Monmouth Beach, NJ. |
| Sunday, August 5 |
| » Lost to Twins (62-47), 8-3 | Tiger Stadium (32-22) | 51-55 | Lost 4 |
| » Starters: Jim Kaat vs Paul Foytack | Seventh | 13½ out |
| » Defeated Twins (62-48), 5-2 | Tiger Stadium (33-22) | 52-55 | |
| » Starters: Jackie Collum vs Howie Koplitz | Seventh | 13½ out |
| Monday, August 6 |
| » Lost to Indians (54-55), 6-5 | Cleveland Stadium (2-6) | 52-56 | |
| » Starters: Hank Aguirre vs Sam McDowell | Seventh | 13½ out |
| Tuesday, August 7 |
| » Lost to Indians (55-55), 4-2 | Cleveland Stadium (2-7) | 52-57 | Lost 2 |
| » Starters: Jim Bunning vs Mudcat Grant | Seventh | 14½ out |
| Wednesday, August 8 |
| » Defeated Senators (42-68), 6-5 | Robert F. Kennedy Stadium (2-5) | 53-57 | |
| » Starters: Don Mossi vs Dave Stenhouse | Seventh | 13½ out |
| » Defeated Senators (42-69), 10-3 | Robert F. Kennedy Stadium (3-5) | 54-57 | Won 2 |
| » Starters: Phil Regan vs Pete Burnside | Seventh | 13½ out |
| Thursday, August 9 |
| » Defeated Senators (42-70), 8-5 | Robert F. Kennedy Stadium (4-5) | 55-57 | Won 3 |
| » Starters: Howie Koplitz vs Tom Cheney | Fifth | 13 out |
| Friday, August 10 |
| » Lost to Yankees (68-43), 8-0 | Yankee Stadium (3-3) | 55-58 | |
| » Starters: Paul Foytack vs Whitey Ford | Seventh | 14 out |
| Saturday, August 11 |
| » Defeated Yankees (68-44), 7-2 | Yankee Stadium (4-3) | 56-58 | |
| » Starters: Hank Aguirre vs Ralph Terry | Seventh | 14 out |
| » Lost to Yankees (69-44), 3-2 | Yankee Stadium (4-4) | 56-59 | |
| » Starters: Jim Bunning vs Bob Turley | Seventh | 14 out |
| Sunday, August 12 |
| » Lost to Yankees (70-44), 2-0 | Yankee Stadium (4-5) | 56-60 | Lost 2 |
| » Starters: Ron Kline vs Bill Stafford | Seventh | 15 out |
| Tuesday, August 14 |
| » Defeated Orioles (58-60), 13-10 | Tiger Stadium (34-22) | 57-60 | |
| » Starters: Jack Fisher vs Howie Koplitz | Fifth | 14 out |
| » Defeated Orioles (58-61), 5-4 | Tiger Stadium (35-22) | 58-60 | Won 2 |
| » Starters: Hal Brown vs Phil Regan | Fifth | 14 out |
| Wednesday, August 15 |
| » Defeated Orioles (58-62), 3-1 | Tiger Stadium (36-22) | 59-60 | Won 3 |
| » Starters: Robin Roberts vs Hank Aguirre | Fifth | 14 out |
| Friday, August 17 |
| » Defeated White Sox (63-60), 2-0 | Comiskey Park I (2-4) | 60-60 | Won 4 |
| » Starters: Jim Bunning vs John Buzhardt | Fifth | 12½ out |
| Saturday, August 18 |
| » Lost to White Sox (64-60), 2-0 | Comiskey Park I (2-5) | 60-61 | |
| » Starters: Ron Kline vs Ray Herbert | Fifth | 13 out |
| Sunday, August 19 |
| » Lost to White Sox (65-60), 11-5 | Comiskey Park I (2-6) | 60-62 | Lost 2 |
| » Starters: Phil Regan vs Frank Baumann | Fifth | 13½ out |
| » Defeated White Sox (65-61), 8-3 | Comiskey Park I (3-6) | 61-62 | |
| » Starters: Howie Koplitz vs Juan Pizarro | Fifth | 13½ out |
| Tuesday, August 21 |
| » Defeated Indians (59-66), 10-1 | Tiger Stadium (37-22) | 62-62 | Won 2 |
| » Starters: Jim Perry vs Jim Bunning | Fifth | 13 out |
| Wednesday, August 22 |
| » Lost to Indians (60-66), 7-3 | Tiger Stadium (37-23) | 62-63 | |
| » Starters: Dick Donovan vs Ron Kline | Fifth | 14 out |
| Thursday, August 23 |
| » Defeated Indians (60-67), 8-5 | Tiger Stadium (38-23) | 63-63 | |
| » Starters: Mudcat Grant vs Hank Aguirre | Fifth | 13 out |
| Friday, August 24 |
| » Defeated Senators (48-80), 11-1 | Tiger Stadium (39-23) | 64-63 | Won 2 |
| » Starters: Pete Burnside vs Phil Regan | Fifth | 11½ out |
| Saturday, August 25 |
| » Defeated Senators (48-81), 7-5 | Tiger Stadium (40-23) | 65-63 | Won 3 |
| » Starters: Steve Hamilton vs Howie Koplitz | Fifth | 10 out |
| Sunday, August 26 |
| » Defeated Senators (48-82), 5-3 | Tiger Stadium (41-23) | 66-63 | Won 4 |
| » Starters: Dave Stenhouse vs Jim Bunning | Fifth | 9½ out |
| » Lost to Senators (49-82), 5-2 | Tiger Stadium (41-24) | 66-64 | |
| » Starters: Claude Osteen vs Ron Kline | Fifth | 9½ out |
| Monday, August 27 |
| » Lost to Red Sox (62-71), 7-4 | Fenway Park (2-5) | 66-65 | Lost 2 |
| » Starters: Hank Aguirre vs Gene Conley | Fifth | 10½ out |
| Thursday, August 30 |
| » Lost to White Sox (69-65), 5-4 | Tiger Stadium (41-25) | 66-66 | Lost 3 |
| » Starters: Frank Baumann vs Phil Regan | Fifth | 10½ out |
| Friday, August 31 |
| » Defeated White Sox (69-66), 5-2 | Tiger Stadium (42-25) | 67-66 | |
| » Starters: John Buzhardt vs Jim Bunning | Fifth | 10½ out |
| Former Tiger Mutt Wilson dies in Wildwood, FL at the age of 67. |
| Saturday, September 1 |
| » Defeated White Sox (69-67), 2-1 | Tiger Stadium (43-25) | 68-66 | Won 2 |
| » Starters: Ray Herbert vs Hank Aguirre | Fifth | 10½ out |
| Sunday, September 2 |
| » Lost to White Sox (70-67), 10-8 | Tiger Stadium (43-26) | 68-67 | |
| » Starters: Eddie Fisher vs Paul Foytack | Sixth | 11½ out |
| » Major-league debuts: Frank Kostro (Tigers) |
| Monday, September 3 |
| » Defeated Orioles (70-69), 1-0 | Memorial Stadium (5-1) | 69-67 | |
| » Starters: Don Mossi vs Dick Hall | Fourth | 10½ out |
| » Defeated Orioles (70-70), 4-1 | Memorial Stadium (6-1) | 70-67 | Won 2 |
| » Starters: Phil Regan vs Chuck Estrada | Fourth | 10½ out |
| Wednesday, September 5 |
| » Defeated Orioles (70-71), 5-2 | Memorial Stadium (7-1) | 71-67 | Won 3 |
| » Starters: Jim Bunning vs Robin Roberts | Fourth | 9 out |
| » Defeated Orioles (70-72), 6-0 | Memorial Stadium (8-1) | 72-67 | Won 4 |
| » Starters: Hank Aguirre vs Jack Fisher | Fourth | 9 out |
| Friday, September 7 |
| » Lost to Twins (81-62), 6-4 | Tiger Stadium (43-27) | 72-68 | |
| » Starters: Jim Kaat vs Phil Regan | Fourth | 10½ out |
| Saturday, September 8 |
| » Lost to Twins (82-62), 9-2 | Tiger Stadium (43-28) | 72-69 | Lost 2 |
| » Starters: Camilo Pascual vs Don Mossi | Fourth | 11½ out |
| » Major-league debuts: Bob Humphreys (Tigers) |
| Sunday, September 9 |
| » Defeated Twins (82-63), 10-9 | Tiger Stadium (44-28) | 73-69 | |
| » Starters: Jack Kralick vs Jim Bunning | Fifth | 10 out |
| » Major-league debuts: Tony Oliva (Twins) |
| Monday, September 10 |
| » Lost to Yankees (86-61), 3-1 | Tiger Stadium (44-29) | 73-70 | |
| » Starters: Ralph Terry vs Hank Aguirre | Fifth | 11 out |
| Tuesday, September 11 |
| » Lost to Yankees (87-61), 8-7 | Tiger Stadium (44-30) | 73-71 | Lost 2 |
| » Starters: Jim Coates vs Frank Lary | Fifth | 12 out |
| » Major-league debuts: Jake Gibbs (Yankees) |
| Wednesday, September 12 |
| » Lost to Red Sox (69-77), 8-6 | Tiger Stadium (44-31) | 73-72 | Lost 3 |
| » Starters: Gene Conley vs Phil Regan | Fifth | 13½ out |
| » Lost to Red Sox (70-77), 6-2 | Tiger Stadium (44-32) | 73-73 | Lost 4 |
| » Starters: Don Schwall vs Paul Foytack | Fifth | 13½ out |
| » Major-league debuts: Tom Fletcher (Tigers) |
| Thursday, September 13 |
| » Defeated Red Sox (70-78), 14-6 | Tiger Stadium (45-32) | 74-73 | |
| » Starters: Pete Smith vs Jim Bunning | Fifth | 13 out |
| » Major-league debuts: Pete Smith (Red Sox) |
| Friday, September 14 |
| » Defeated Angels (82-67), 3-2 | Dodger Stadium (3-4) | 75-73 | Won 2 |
| » Starters: Hank Aguirre vs Dean Chance | Fifth | 12 out |
| Saturday, September 15 |
| » Defeated Angels (82-68), 7-3 | Dodger Stadium (4-4) | 76-73 | Won 3 |
| » Starters: Don Mossi vs Eli Grba | Fifth | 12 out |
| Sunday, September 16 |
| » Defeated Angels (82-69), 4-2 | Dodger Stadium (5-4) | 77-73 | Won 4 |
| » Starters: Phil Regan vs Ken McBride | Fifth | 11 out |
| » Major-league debuts: Fred Newman (Angels) |
| Tuesday, September 18 |
| » Defeated Twins (86-67), 2-1 | Metropolitan Stadium (2-5) | 78-73 | Won 5 |
| » Starters: Jim Bunning vs Jack Kralick | Fifth | 11 out |
| Wednesday, September 19 |
| » Lost to Twins (87-67), 12-5 | Metropolitan Stadium (2-6) | 78-74 | |
|
