| Thursday, January 4 |
| Future Oriole Jay Tibbs is born in Birmingham, AL. |
| Friday, January 19 |
| Future Oriole Chris Sabo is born in Detroit, MI. |
| Friday, January 26 |
| Future Oriole Rick Schu is born in Philadelphia, PA. |
| Friday, February 2 |
| Future Oriole Paul Kilgus is born in Bowling Green, KY. |
| Sunday, April 1 |
| Future Oriole Rich Amaral is born in Visalia, CA. |
| Tuesday, April 10 |
| » Lost to Yankees (1-0), 7-6 | Yankee Stadium (0-1) | 0-1 | |
| » Starters: Billy Hoeft vs Whitey Ford | Second | 1 out |
| » Major-league debuts: Joe Pepitone (Yankees) |
| Thursday, April 12 |
| » Major-league debuts: Diego Segui (Athletics) |
| Friday, April 13 |
| » Major-league debuts: Phil Linz (Yankees) |
| Saturday, April 14 |
| » Defeated Red Sox (1-2), 3-0 | Memorial Stadium (1-0) | 1-1 | |
| » Starters: Gene Conley vs Chuck Estrada | Second | ½ out |
| Sunday, April 15 |
| » Defeated Red Sox (1-3), 5-1 | Memorial Stadium (2-0) | 2-1 | Won 2 |
| » Starters: Don Schwall vs Steve Barber | Fourth | 1 out |
| » Lost to Red Sox (2-3), 5-4 | Memorial Stadium (2-1) | 2-2 | |
| » Starters: Galen Cisco vs Billy Hoeft | Fourth | 1 out |
| » Major-league debuts: Bob Tillman (Red Sox) |
| Monday, April 16 |
| » Major-league debuts: Hank Fischer (Braves) |
| Tuesday, April 17 |
| » Lost to Yankees (3-1), 8-3 | Memorial Stadium (2-2) | 2-3 | Lost 2 |
| » Starters: Whitey Ford vs Hal Brown | Sixth | 1½ out |
| Wednesday, April 18 |
| » Defeated Yankees (3-2), 1-0 | Memorial Stadium (3-2) | 3-3 | |
| » Starters: Bill Stafford vs Milt Pappas | Fourth | 1½ out |
| Thursday, April 19 |
| » Lost to Yankees (4-2), 3-1 | Memorial Stadium (3-3) | 3-4 | |
| » Starters: Ralph Terry vs Chuck Estrada | Sixth | 2½ out |
| Friday, April 20 |
| » Defeated Senators (2-4), 5-4 | Robert F. Kennedy Stadium (1-0) | 4-4 | |
| » Starters: Billy Hoeft vs Pete Burnside | Sixth | 1½ out |
| Saturday, April 21 |
| » Defeated Senators (2-5), 3-0 | Robert F. Kennedy Stadium (2-0) | 5-4 | Won 2 |
| » Starters: Art Quirk vs Claude Osteen | Third | 1 out |
| Sunday, April 22 |
| » Defeated Senators (2-6), 8-3 | Robert F. Kennedy Stadium (3-0) | 6-4 | Won 3 |
| » Starters: Steve Barber vs Bennie Daniels | Second | 1 out |
| Tuesday, April 24 |
| » Defeated Twins (5-7), 5-4 | Memorial Stadium (4-3) | 7-4 | Won 4 |
| » Starters: Jack Kralick vs Milt Pappas | Second | 1 out |
| Wednesday, April 25 |
| » Lost to Twins (6-7), 3-1 | Memorial Stadium (4-4) | 7-5 | |
| » Starters: Don Lee vs Chuck Estrada | Second | 1 out |
| Thursday, April 26 |
| » Lost to Twins (7-7), 3-2 | Memorial Stadium (4-5) | 7-6 | Lost 2 |
| » Starters: Camilo Pascual vs Hal Brown | Fourth | 1 out |
| Friday, April 27 |
| » Lost to Athletics (9-8), 14-5 | Municipal Stadium (0-1) | 7-7 | Lost 3 |
| » Starters: Art Quirk vs Ed Rakow | Sixth | 2 out |
| Saturday, April 28 |
| » Defeated Athletics (9-9), 3-2 | Municipal Stadium (1-1) | 8-7 | |
| » Starters: Steve Barber vs Norm Bass | Fifth | 2 out |
| Sunday, April 29 |
| » Defeated Athletics (9-10), 8-3 | Municipal Stadium (2-1) | 9-7 | Won 2 |
| » Starters: Milt Pappas vs Dan Pfister | Fifth | 1½ out |
| Tuesday, May 1 |
| » Lost to Twins (10-9), 8-3 | Metropolitan Stadium (0-1) | 9-8 | |
| » Starters: Chuck Estrada vs Camilo Pascual | Fifth | 2½ out |
| Wednesday, May 2 |
| » Defeated Twins (10-10), 6-5 | Metropolitan Stadium (1-1) | 10-8 | |
| » Starters: Hal Brown vs Jim Kaat | Third | 2½ out |
| » Major-league debuts: Marty Martinez (Twins) |
| Thursday, May 3 |
| » Lost to Twins (11-10), 8-4 | Metropolitan Stadium (1-2) | 10-9 | |
| » Starters: Milt Pappas vs Jack Kralick | Fifth | 2½ out |
| Friday, May 4 |
| » Lost to Angels (9-9), 5-4 | Dodger Stadium (0-1) | 10-10 | Lost 2 |
| » Starters: Art Quirk vs Ted Bowsfield | Fifth | 3 out |
| Saturday, May 5 |
| » Lost to Angels (10-9), 2-0 | Dodger Stadium (0-2) | 10-11 | Lost 3 |
| » Starters: Steve Barber vs Bo Belinsky | Eighth | 4 out |
| Sunday, May 6 |
| » Lost to Angels (11-9), 15-7 | Dodger Stadium (0-3) | 10-12 | Lost 4 |
| » Starters: Chuck Estrada vs Ken McBride | Eighth | 4½ out |
| Wednesday, May 9 |
| » Defeated Athletics (12-15), 6-3 | Memorial Stadium (5-5) | 11-12 | |
| » Starters: Ed Rakow vs Milt Pappas | Sixth | 4½ out |
| Thursday, May 10 |
| » Defeated Athletics (12-16), 5-2 | Memorial Stadium (6-5) | 12-12 | Won 2 |
| » Starters: Jerry Walker vs Chuck Estrada | Sixth | 4 out |
| Friday, May 11 |
| » Lost to Senators (6-18), 12-1 | Memorial Stadium (6-6) | 12-13 | |
| » Starters: Dave Stenhouse vs Art Quirk | Seventh | 4 out |
| Saturday, May 12 |
| » Defeated Senators (6-19), 3-2 | Memorial Stadium (7-6) | 13-13 | |
| » Starters: Pete Burnside vs Steve Barber | Sixth | 4 out |
| Sunday, May 13 |
| » Defeated Senators (6-20), 3-2 | Memorial Stadium (8-6) | 14-13 | Won 2 |
| » Starters: Don Rudolph vs Jack Fisher | Fifth | 3 out |
| Tuesday, May 15 |
| » Defeated Angels (13-14), 7-1 | Memorial Stadium (9-6) | 15-13 | Won 3 |
| » Starters: Ted Bowsfield vs Milt Pappas | Fifth | 2 out |
| Wednesday, May 16 |
| » Lost to Angels (14-14), 3-1 | Memorial Stadium (9-7) | 15-14 | |
| » Starters: Ken McBride vs Chuck Estrada | Fifth | 3 out |
| Thursday, May 17 |
| » Defeated Angels (14-15), 6-4 | Memorial Stadium (10-7) | 16-14 | |
| » Starters: Bo Belinsky vs Art Quirk | Fourth | 2½ out |
| Friday, May 18 |
| » Defeated White Sox (18-16), 7-4 | Comiskey Park I (1-0) | 17-14 | Won 2 |
| » Starters: Jack Fisher vs Juan Pizarro | Fourth | 2½ out |
| Saturday, May 19 |
| » Defeated White Sox (18-17), 11-6 | Comiskey Park I (2-0) | 18-14 | Won 3 |
| » Starters: Steve Barber vs Joe Horlen | Third | 1½ out |
| Sunday, May 20 |
| » Lost to White Sox (19-17), 8-3 | Comiskey Park I (2-1) | 18-15 | |
| » Starters: Milt Pappas vs John Buzhardt | Fifth | 2½ out |
| » Lost to White Sox (20-17), 8-3 | Comiskey Park I (2-2) | 18-16 | Lost 2 |
| » Starters: Chuck Estrada vs Ray Herbert | Fifth | 2½ out |
| Monday, May 21 |
| » Lost to Indians (21-13), 10-7 | Cleveland Stadium (0-1) | 18-17 | Lost 3 |
| » Starters: Hal Brown vs Mudcat Grant | Sixth | 3½ out |
| Tuesday, May 22 |
| » Defeated Indians (21-14), 4-1 | Cleveland Stadium (1-1) | 19-17 | |
| » Starters: Milt Pappas vs Jim Perry | Fifth | 3 out |
| Thursday, May 24 |
| » Lost to Tigers (17-17), 5-4 | Memorial Stadium (10-8) | 19-18 | |
| » Starters: Jim Bunning vs Jack Fisher | Fifth | 4½ out |
| Friday, May 25 |
| » Defeated Red Sox (15-23), 9-5 | Fenway Park (1-0) | 20-18 | |
| » Starters: Chuck Estrada vs Bill Monbouquette | Fourth | 3½ out |
| Saturday, May 26 |
| » Lost to Red Sox (16-23), 12-6 | Fenway Park (1-1) | 20-19 | |
| » Starters: Steve Barber vs Gene Conley | Fifth | 3½ out |
| Sunday, May 27 |
| » Defeated Red Sox (16-24), 4-2 | Fenway Park (2-1) | 21-19 | |
| » Starters: Robin Roberts vs Ike Delock | Fifth | 3½ out |
| Monday, May 28 |
| » Lost to Tigers (21-18), 5-1 | Tiger Stadium (0-1) | 21-20 | |
| » Starters: Milt Pappas vs Jim Bunning | Fifth | 3½ out |
| Tuesday, May 29 |
| » Lost to Tigers (22-18), 12-4 | Tiger Stadium (0-2) | 21-21 | Lost 2 |
| » Starters: Jack Fisher vs Don Mossi | Sixth | 4 out |
| Future Oriole Eric Davis is born in Los Angeles, CA. |
| Wednesday, May 30 |
| » Lost to Indians (25-16), 7-0 | Memorial Stadium (10-9) | 21-22 | Lost 3 |
| » Starters: Pedro Ramos vs Chuck Estrada | Sixth | 4 out |
| » Defeated Indians (25-17), 7-0 | Memorial Stadium (11-9) | 22-22 | |
| » Starters: Barry Latman vs Hal Brown | Sixth | 4 out |
| Thursday, May 31 |
| » Lost to Indians (26-17), 4-3 | Memorial Stadium (11-10) | 22-23 | |
| » Starters: Mudcat Grant vs Robin Roberts | Sixth | 5 out |
| Future Oriole Joe Orsulak is born in Glen Ridge, NJ. |
| Friday, June 1 |
| » Lost to White Sox (24-24), 3-2 | Memorial Stadium (11-11) | 22-24 | Lost 2 |
| » Starters: Ray Herbert vs Milt Pappas | Eighth | 6 out |
| Saturday, June 2 |
| » Lost to White Sox (25-24), 10-2 | Memorial Stadium (11-12) | 22-25 | Lost 3 |
| » Starters: Juan Pizarro vs Steve Barber | Seventh | 5½ out |
| » Defeated White Sox (25-25), 11-4 | Memorial Stadium (12-12) | 23-25 | |
| » Starters: Early Wynn vs Jack Fisher | Seventh | 5½ out |
| Sunday, June 3 |
| » Lost to White Sox (26-25), 2-0 | Memorial Stadium (12-13) | 23-26 | |
| » Starters: John Buzhardt vs Chuck Estrada | Seventh | 5½ out |
| Tuesday, June 5 |
| » Defeated Senators (14-34), 6-5 | Memorial Stadium (13-13) | 24-26 | |
| » Starters: Don Rudolph vs Milt Pappas | Seventh | 5 out |
| Wednesday, June 6 |
| » Lost to Senators (15-34), 2-1 | Memorial Stadium (13-14) | 24-27 | |
| » Starters: Claude Osteen vs Robin Roberts | Eighth | 6 out |
| Thursday, June 7 |
| » Defeated Senators (15-35), 12-5 | Memorial Stadium (14-14) | 25-27 | |
| » Starters: Pete Burnside vs Jack Fisher | Seventh | 6 out |
| Friday, June 8 |
| » Lost to Yankees (30-19), 1-0 | Yankee Stadium (0-2) | 25-28 | |
| » Starters: Chuck Estrada vs Whitey Ford | Seventh | 7 out |
| Saturday, June 9 |
| » Lost to Yankees (31-19), 7-3 | Yankee Stadium (0-3) | 25-29 | Lost 2 |
| » Starters: Steve Barber vs Rollie Sheldon | Sixth | 8 out |
| Sunday, June 10 |
| » Defeated Yankees (31-20), 5-1 | Yankee Stadium (1-3) | 26-29 | |
| » Starters: Milt Pappas vs Ralph Terry | Seventh | 6 out |
| » Defeated Yankees (31-21), 7-2 | Yankee Stadium (2-3) | 27-29 | Won 2 |
| » Starters: Hal Brown vs Bob Turley | Seventh | 6 out |
| Monday, June 11 |
| » Defeated Yankees (31-22), 5-3 | Yankee Stadium (3-3) | 28-29 | Won 3 |
| » Starters: Robin Roberts vs Bud Daley | Sixth | 5½ out |
| Tuesday, June 12 |
| » Lost to Red Sox (23-32), 4-3 | Fenway Park (2-2) | 28-30 | |
| » Starters: Jack Fisher vs Ike Delock | Seventh | 6 out |
| Wednesday, June 13 |
| » Lost to Red Sox (24-32), 4-0 | Fenway Park (2-3) | 28-31 | Lost 2 |
| » Starters: Chuck Estrada vs Don Schwall | Seventh | 6½ out |
| Thursday, June 14 |
| » Defeated Red Sox (24-33), 7-4 | Fenway Park (3-3) | 29-31 | |
| » Starters: Steve Barber vs Bill Monbouquette | Sixth | 6 out |
| Friday, June 15 |
| » Defeated Senators (21-38), 8-3 | Robert F. Kennedy Stadium (4-0) | 30-31 | Won 2 |
| » Starters: Milt Pappas vs Don Rudolph | Sixth | 5 out |
| Saturday, June 16 |
| » Defeated Senators (21-39), 4-3 | Robert F. Kennedy Stadium (5-0) | 31-31 | Won 3 |
| » Starters: Robin Roberts vs Pete Burnside | Fifth | 5 out |
| Sunday, June 17 |
| » Defeated Senators (21-40), 4-3 | Robert F. Kennedy Stadium (6-0) | 32-31 | Won 4 |
| » Starters: Hal Brown vs Bennie Daniels | Fifth | 5½ out |
| Tuesday, June 19 |
| » Defeated Yankees (32-27), 3-1 | Memorial Stadium (15-14) | 33-31 | Won 5 |
| » Starters: Ralph Terry vs Chuck Estrada | Fifth | 4½ out |
| Thursday, June 21 |
| » Lost to Yankees (33-27), 3-0 | Memorial Stadium (15-15) | 33-32 | |
| » Starters: Whitey Ford vs Steve Barber | Fifth | 5½ out |
| Friday, June 22 |
| » Lost to Red Sox (30-36), 2-1 | Memorial Stadium (15-16) | 33-33 | Lost 2 |
| » Starters: Ike Delock vs Milt Pappas | Sixth | 6 out |
| » Defeated Red Sox (30-37), 4-3 | Memorial Stadium (16-16) | 34-33 | |
| » Starters: Don Schwall vs Robin Roberts | Sixth | 6 out |
| Saturday, June 23 |
| » Defeated Red Sox (30-38), 5-3 | Memorial Stadium (17-16) | 35-33 | Won 2 |
| » Starters: Galen Cisco vs Hal Brown | Fifth | 5 out |
| Sunday, June 24 |
| » Lost to Red Sox (31-38), 3-2 | Memorial Stadium (17-17) | 35-34 | |
| » Starters: Bill Monbouquette vs Chuck Estrada | Sixth | 6 out |
| » Lost to Red Sox (32-38), 8-5 | Memorial Stadium (17-18) | 35-35 | Lost 2 |
| » Starters: Gene Conley vs Steve Barber | Sixth | 6 out |
| Tuesday, June 26 |
| » Defeated White Sox (36-37), 1-0 | Memorial Stadium (18-18) | 36-35 | |
| » Starters: John Buzhardt vs Milt Pappas | Fifth | 5½ out |
| Wednesday, June 27 |
| » Defeated White Sox (36-38), 3-1 | Memorial Stadium (19-18) | 37-35 | Won 2 |
| » Starters: Juan Pizarro vs Robin Roberts | Fifth | 4½ out |
| Thursday, June 28 |
| » Defeated White Sox (36-39), 6-0 | Memorial Stadium (20-18) | 38-35 | Won 3 |
| » Starters: Dom Zanni vs Steve Barber | Fifth | 4 out |
| Friday, June 29 |
| » Lost to Tigers (36-35), 1-0 | Memorial Stadium (20-19) | 38-36 | |
| » Starters: Hank Aguirre vs Chuck Estrada | Fifth | 4 out |
| Saturday, June 30 |
| » Defeated Tigers (36-36), 6-3 | Memorial Stadium (21-19) | 39-36 | |
| » Starters: Frank Lary vs Jack Fisher | Fifth | 3½ out |
| » Lost to Tigers (37-36), 7-4 | Memorial Stadium (21-20) | 39-37 | |
| » Starters: Don Mossi vs Milt Pappas | Fifth | 3½ out |
| Sunday, July 1 |
| » Lost to Tigers (38-36), 3-2 | Memorial Stadium (21-21) | 39-38 | Lost 2 |
| » Starters: Jim Bunning vs Robin Roberts | Seventh | 3½ out |
| Monday, July 2 |
| » Lost to Indians (42-34), 2-0 | Cleveland Stadium (1-2) | 39-39 | Lost 3 |
| » Starters: Steve Barber vs Dick Donovan | Sixth | 4½ out |
| Wednesday, July 4 |
| » Defeated White Sox (40-42), 7-3 | Comiskey Park I (3-2) | 40-39 | |
| » Starters: Milt Pappas vs Ray Herbert | Sixth | 5½ out |
| » Lost to White Sox (41-42), 5-2 | Comiskey Park I (3-3) | 40-40 | |
| » Starters: Chuck Estrada vs Juan Pizarro | Sixth | 5½ out |
| Thursday, July 5 |
| » Defeated White Sox (41-43), 5-4 | Comiskey Park I (4-3) | 41-40 | |
| » Starters: Jack Fisher vs Frank Baumann | Fourth | 5 out |
| Friday, July 6 |
| » Lost to Tigers (41-39), 5-4 | Tiger Stadium (0-3) | 41-41 | |
| » Starters: Robin Roberts vs Jim Bunning | Sixth | 6 out |
| Saturday, July 7 |
| » Defeated Tigers (41-40), 7-6 | Tiger Stadium (1-3) | 42-41 | |
| » Starters: Chuck Estrada vs Sam Jones | Fifth | 6 out |
| Sunday, July 8 |
| » Lost to Tigers (42-40), 5-1 | Tiger Stadium (1-4) | 42-42 | |
| » Starters: Milt Pappas vs Paul Foytack | Sixth | 7 out |
| » Lost to Tigers (43-40), 3-2 | Tiger Stadium (1-5) | 42-43 | Lost 2 |
| » Starters: Steve Barber vs Hank Aguirre | Sixth | 7 out |
| Thursday, July 12 |
| » Lost to Indians (48-36), 6-4 | Memorial Stadium (21-22) | 42-44 | Lost 3 |
| » Starters: Ruben Gomez vs Robin Roberts | Seventh | 7 out |
| Friday, July 13 |
| » Defeated Indians (48-37), 10-3 | Memorial Stadium (22-22) | 43-44 | |
| » Starters: Jim Perry vs Steve Barber | Seventh | 6 out |
| Saturday, July 14 |
| » Defeated Indians (48-38), 4-3 | Memorial Stadium (23-22) | 44-44 | Won 2 |
| » Starters: Dick Donovan vs Milt Pappas | Seventh | 6 out |
| Sunday, July 15 |
| » Defeated Indians (48-39), 6-4 | Cleveland Stadium (2-2) | 45-44 | Won 3 |
| » Starters: Chuck Estrada vs Mudcat Grant | Sixth | 6 out |
| » Defeated Indians (48-40), 6-5 | Cleveland Stadium (3-2) | 46-44 | Won 4 |
| » Starters: Jack Fisher vs Pedro Ramos | Sixth | 6 out |
| Tuesday, July 17 |
| » Defeated Athletics (41-52), 3-2 | Municipal Stadium (3-1) | 47-44 | Won 5 |
| » Starters: Robin Roberts vs Ed Rakow | Fifth | 6½ out |
| Wednesday, July 18 |
| » Lost to Athletics (42-52), 3-2 | Municipal Stadium (3-2) | 47-45 | |
| » Starters: Milt Pappas vs Bob Giggie | Fifth | 7½ out |
| Thursday, July 19 |
| » Defeated Athletics (42-53), 7-3 | Municipal Stadium (4-2) | 48-45 | |
| » Starters: Steve Barber vs Bill Fischer | Fifth | 7½ out |
| Friday, July 20 |
| » Lost to Twins (51-43), 7-5 | Metropolitan Stadium (1-3) | 48-46 | |
| » Starters: Chuck Estrada vs Jack Kralick | Fifth | 8½ out |
| Saturday, July 21 |
| » Lost to Twins (52-43), 7-6 | Metropolitan Stadium (1-4) | 48-47 | Lost 2 |
| » Starters: Jack Fisher vs Joe Bonikowski | Fifth | 9½ out |
| Sunday, July 22 |
| » Defeated Twins (52-44), 8-6 | Metropolitan Stadium (2-4) | 49-47 | |
| » Starters: Robin Roberts vs Camilo Pascual | Fifth | 8 out |
| Monday, July 23 |
| » Lost to Angels (54-41), 6-5 | Dodger Stadium (0-4) | 49-48 | |
| » Starters: Milt Pappas vs Eli Grba | Fifth | 8½ out |
| Tuesday, July 24 |
| » Defeated Angels (54-42), 3-2 | Dodger Stadium (1-4) | 50-48 | |
| » Starters: Steve Barber vs Bo Belinsky | Fifth | 9 out |
| » Lost to Angels (55-42), 8-5 | Dodger Stadium (1-5) | 50-49 | |
| » Starters: Chuck Estrada vs Ted Bowsfield | Fifth | 9 out |
| Wednesday, July 25 |
| » Lost to Angels (56-42), 5-0 | Dodger Stadium (1-6) | 50-50 | Lost 2 |
| » Starters: Jack Fisher vs Don Lee | Fifth | 9½ out |
| Future Oriole Doug Drabek is born in Victoria, TX. |
| Friday, July 27 |
| » Defeated Athletics (44-57), 3-2 | Memorial Stadium (24-22) | 51-50 | |
| » Starters: Dan Pfister vs Robin Roberts | Fifth | 10 out |
| Saturday, July 28 |
| » Defeated Athletics (44-58), 3-0 | Memorial Stadium (25-22) | 52-50 | Won 2 |
| » Starters: Ed Rakow vs Steve Barber | Fourth | 9½ out |
| » Defeated Athletics (44-59), 7-1 | Memorial Stadium (26-22) | 53-50 | Won 3 |
| » Starters: Jerry Walker vs Dick Hall | Fourth | 9½ out |
| Sunday, July 29 |
| » Lost to Athletics (45-59), 7-3 | Memorial Stadium (26-23) | 53-51 | |
| » Starters: Bill Fischer vs Chuck Estrada | Fourth | 10 out |
| Tuesday, July 31 |
| » Defeated Twins (57-47), 8-7 | Memorial Stadium (27-23) | 54-51 | |
| » Starters: Jackie Collum vs Jack Fisher | Fifth | 10 out |
| Wednesday, August 1 |
| » Lost to Twins (58-47), 3-1 | Memorial Stadium (27-24) | 54-52 | |
| » Starters: Jim Kaat vs Robin Roberts | Fourth | 11½ out |
| Thursday, August 2 |
| » Lost to Twins (59-47), 6-3 | Memorial Stadium (27-25) | 54-53 | Lost 2 |
| » Starters: Dick Stigman vs Dick Hall | Fourth | 12 out |
| Friday, August 3 |
| » Defeated Angels (60-47), 6-3 | Memorial Stadium (28-25) | 55-53 | |
| » Starters: Ken McBride vs Milt Pappas | Third | 12 out |
| Saturday, August 4 |
| » Defeated Angels (60-48), 3-1 | Memorial Stadium (29-25) | 56-53 | Won 2 |
| » Starters: Don Lee vs Jack Fisher | Fourth | 11 out |
| Sunday, August 5 |
| » Defeated Angels (60-49), 7-2 | Memorial Stadium (30-25) | 57-53 | Won 3 |
| » Starters: Eli Grba vs Robin Roberts | Fourth | 10 out |
| Monday, August 6 |
| » Lost to White Sox (55-56), 5-4 | Comiskey Park I (4-4) | 57-54 | |
| » Starters: Chuck Estrada vs Early Wynn | Fourth | 10 out |
| Tuesday, August 7 |
| » Lost to White Sox (56-56), 4-0 | Comiskey Park I (4-5) | 57-55 | Lost 2 |
| » Starters: Dick Hall vs Ray Herbert | Fourth | 11 out |
| Wednesday, August 8 |
| » Lost to Yankees (67-42), 3-2 | Yankee Stadium (3-4) | 57-56 | Lost 3 |
| » Starters: Milt Pappas vs Bill Stafford | Fourth | 11 out |
| » Defeated Yankees (67-43), 4-3 | Yankee Stadium (4-4) | 58-56 | |
| » Starters: Jack Fisher vs Jim Bouton | Fourth | 11 out |
| Saturday, August 11 |
| » Lost to Red Sox (52-61), 3-0 | Fenway Park (3-4) | 58-57 | |
| » Starters: Robin Roberts vs Ike Delock | Fifth | 12½ out |
| » Lost to Red Sox (53-61), 7-3 | Fenway Park (3-5) | 58-58 | Lost 2 |
| » Starters: Chuck Estrada vs Don Schwall | Fifth | 12½ out |
| Sunday, August 12 |
| » Lost to Red Sox (54-61), 4-1 | Fenway Park (3-6) | 58-59 | Lost 3 |
| » Starters: Milt Pappas vs Earl Wilson | Sixth | 13½ out |
| Tuesday, August 14 |
| » Lost to Tigers (57-60), 13-10 | Tiger Stadium (1-6) | 58-60 | Lost 4 |
| » Starters: Jack Fisher vs Howie Koplitz | Sixth | 14½ out |
| » Lost to Tigers (58-60), 5-4 | Tiger Stadium (1-7) | 58-61 | Lost 5 |
| » Starters: Hal Brown vs Phil Regan | Sixth | 14½ out |
| Wednesday, August 15 |
| » Lost to Tigers (59-60), 3-1 | Tiger Stadium (1-8) | 58-62 | Lost 6 |
| » Starters: Robin Roberts vs Hank Aguirre | Sixth | 15½ out |
| Friday, August 17 |
| » Defeated Indians (58-64), 5-2 | Memorial Stadium (31-25) | 59-62 | |
| » Starters: Dick Donovan vs Milt Pappas | Sixth | 14 out |
| Saturday, August 18 |
| » Lost to Indians (59-64), 4-3 | Memorial Stadium (31-26) | 59-63 | |
| » Starters: Pedro Ramos vs Chuck Estrada | Sixth | 14½ out |
| Sunday, August 19 |
| » Defeated Indians (59-65), 6-5 | Memorial Stadium (32-26) | 60-63 | |
| » Starters: Barry Latman vs Jack Fisher | Sixth | 14½ out |
| Tuesday, August 21 |
| » Defeated White Sox (65-62), 9-1 | Memorial Stadium (33-26) | 61-63 | Won 2 |
| » Starters: Early Wynn vs Robin Roberts | Sixth | 14 out |
| Wednesday, August 22 |
| » Lost to White Sox (66-62), 7-6 | Memorial Stadium (33-27) | 61-64 | |
| » Starters: John Buzhardt vs Milt Pappas | Sixth | 15 out |
| Friday, August 24 |
| » Defeated Yankees (76-51), 6-2 | Memorial Stadium (34-27) | 62-64 | |
| » Starters: Jim Bouton vs Chuck Estrada | Sixth | 12½ out |
| » Defeated Yankees (76-52), 14-2 | Memorial Stadium (35-27) | 63-64 | Won 2 |
| » Starters: Bob Turley vs Jack Fisher | Sixth | 12½ out |
| Saturday, August 25 |
| » Defeated Yankees (76-53), 8-6 | Memorial Stadium (36-27) | 64-64 | Won 3 |
| » Starters: Jim Coates vs Dick Hall | Sixth | 10½ out |
| » Defeated Yankees (76-54), 4-3 | Memorial Stadium (37-27) | 65-64 | Won 4 |
| » Starters: Bud Daley vs Hal Brown | Sixth | 10½ out |
| Sunday, August 26 |
| » Defeated Yankees (76-55), 2-1 | Memorial Stadium (38-27) | 66-64 | Won 5 |
| » Starters: Whitey Ford vs Robin Roberts | Fifth | 9½ out |
| Monday, August 27 |
| » Lost to Senators (50-82), 7-0 | Robert F. Kennedy Stadium (6-1) | 66-65 | |
| » Starters: Billy Hoeft vs Tom Cheney | Fifth | 10½ out |
| Tuesday, August 28 |
| » Lost to Senators (51-82), 4-0 | Robert F. Kennedy Stadium (6-2) | 66-66 | Lost 2 |
| » Starters: Jack Fisher vs Don Rudolph | Sixth | 11½ out |
| Wednesday, August 29 |
| » Defeated Senators (51-83), 9-3 | Robert F. Kennedy Stadium (7-2) | 67-66 | |
| » Starters: Chuck Estrada vs Bennie Daniels | Fifth | 10 out |
| Thursday, August 30 |
| » Lost to Senators (52-83), 3-2 | Memorial Stadium (38-28) | 67-67 | |
| » Starters: Dave Stenhouse vs Dick Hall | Sixth | 10½ out |
| Friday, August 31 |
| » Lost to Indians (66-70), 9-6 | Cleveland Stadium (3-3) | 67-68 | Lost 2 |
| » Starters: Robin Roberts vs Dick Donovan | Sixth | 11½ out |
| Saturday, September 1 |
| » Defeated Indians (66-71), 8-2 | Cleveland Stadium (4-3) | 68-68 | |
| » Starters: Jack Fisher vs Sam McDowell | Sixth | 11½ out |
| Sunday, September 2 |
| » Defeated Indians (66-72), 4-1 | Cleveland Stadium (5-3) | 69-68 | Won 2 |
| » Starters: Milt Pappas vs Mudcat Grant | Fifth | 11 out |
| » Defeated Indians (66-73), 2-1 | Cleveland Stadium (6-3) | 70-68 | Won 3 |
| » Starters: Hal Brown vs Jim Perry | Fifth | 11 out |
| Monday, September 3 |
| » Lost to Tigers (69-67), 1-0 | Memorial Stadium (38-29) | 70-69 | |
| » Starters: Don Mossi vs Dick Hall | Sixth | 12 out |
| » Lost to Tigers (70-67), 4-1 | Memorial Stadium (38-30) | 70-70 | Lost 2 |
| » Starters: Phil Regan vs Chuck Estrada | Sixth | 12 out |
| Wednesday, September 5 |
| » Lost to Tigers (71-67), 5-2 | Memorial Stadium (38-31) | 70-71 | Lost 3 |
| » Starters: Jim Bunning vs Robin Roberts | Sixth | 12½ out |
| » Lost to Tigers (72-67), 6-0 | Memorial Stadium (38-32) | 70-72 | Lost 4 |
| » Starters: Hank Aguirre vs Jack Fisher | Sixth | 12½ out |
| Friday, September 7 |
| » Lost to Angels (79-63), 5-4 | Memorial Stadium (38-33) | 70-73 | Lost 5 |
| » Starters: Eli Grba vs Milt Pappas | Sixth | 14 out |
| Saturday, September 8 |
| » Lost to Angels (80-63), 2-1 | Memorial Stadium (38-34) | 70-74 | Lost 6 |
| » Starters: Bo Belinsky vs Chuck Estrada | Sixth | 15 out |
| Sunday, September 9 |
| » Defeated Angels (80-64), 4-3 | Memorial Stadium (39-34) | 71-74 | |
| » Starters: Ted Bowsfield vs Jack Fisher | Sixth | 13½ out |
| Monday, September 10 |
| » Defeated Red Sox (68-77), 2-1 | Memorial Stadium (40-34) | 72-74 | Won 2 |
| » Starters: Earl Wilson vs Robin Roberts | Sixth | 13½ out |
| Tuesday, September 11 |
| » Major-league debuts: Jake Gibbs (Yankees) |
| Wednesday, September 12 |
| » Lost to Senators (57-92), 2-1 | Memorial Stadium (40-35) | 72-75 | |
| » Starters: Tom Cheney vs Milt Pappas | Sixth | 15 out |
| Thursday, September 13 |
| » Defeated Senators (57-93), 7-1 | Memorial Stadium (41-35) | 73-75 | |
| » Starters: Don Rudolph vs Chuck Estrada | Sixth | 14½ out |
| Saturday, September 15 |
| » Lost to Athletics (66-82), 4-3 | Municipal Stadium (4-3) | 73-76 | |
| » Starters: Jack Fisher vs Ed Rakow | Sixth | 15½ out |
| » Lost to Athletics (67-82), 5-4 | Municipal Stadium (4-4) | 73-77 | Lost 2 |
| » Starters: Robin Roberts vs Bill Fischer | Sixth | 15½ out |
| Sunday, September 16 |
| » Lost to Athletics (68-82), 12-5 | Municipal Stadium (4-5) | 73-78 | Lost 3 |
| » Starters: Milt Pappas vs Orlando Pena | Sixth | 15½ out |
| Monday, September 17 |
| » Major-league debuts: Ken McMullen (Dodgers) |
| Tuesday, September 18 |
| » Defeated Angels (82-70), 5-2 | Dodger Stadium (2-6) | 74-78 | |
| » Starters: Chuck Estrada vs Bo Belinsky | Sixth | 15½ out |
| Wednesday, September 19 |
| » Lost to Angels (83-70), 9-4 | Dodger Stadium (2-7) | 74-79 | |
| » Starters: Jack Fisher vs Dean Chance | Sixth | 16½ out |
| Future Oriole Randy Myers is born in Vancouver, WA. |
| Thursday, September 20 |
| » Major-league debuts: Jim Roland (Twins) |
| Friday, September 21 |
| » Defeated Twins (87-69), 3-2 | Memorial Stadium (42-35) | 75-79 | |
| » Starters: Camilo Pascual vs Robin Roberts | Sixth | 15½ out |
| » Major-league debuts: Pete Ward (Orioles) |
| Saturday, September 22 |
| » Defeated Twins (87-70), 5-3 | Memorial Stadium (43-35) | 76-79 | Won 2 |
| » Starters: Jack Kralick vs Milt Pappas | Sixth | 14½ out |
| » Major-league debuts: John Miller (Orioles) |
| Sunday, September 23 |
| » Lost to Twins (88-70), 9-2 | Memorial Stadium (43-36) | 76-80 | |
| » Starters: Dick Stigman vs Chuck Estrada | Sixth | 15½ out |
| Monday, September 24 |
| » Lost to Athletics (71-86), 5-2 | Memorial Stadium (43-37) | 76-81 | Lost 2 |
| » Starters: Ed Rakow vs Jack Fisher | Sixth | 16 out |
| Wednesday, September 26 |
| » Defeated Athletics (71-87), 3-0 | Memorial Stadium (44-37) | 77-81 | |
| » Starters: B |
