| Friday, January 5 |
| Future Cardinal Danny Jackson is born in San Antonio, TX. Former Cardinal Frank Snyder dies in San Antonio, TX at the age of 69 |
| Wednesday, January 10 |
| Future Cardinal Jim Lindeman is born in Evanston, IL. |
| Sunday, January 14 |
| Former Cardinal Pep Young dies in Jamestown, NC at the age of 55. |
| Friday, January 19 |
| Future Cardinal Chris Sabo is born in Detroit, MI. |
| Saturday, January 27 |
| Former Cardinal Bob Steele dies in Ocala, FL at the age of 69. |
| Friday, February 2 |
| Future Cardinal Paul Kilgus is born in Bowling Green, KY. |
| Saturday, February 10 |
| Former Cardinal Roy Walker dies in New Orleans, LA at the age of 69. |
| Thursday, March 1 |
| Former Cardinal Hal Janvrin dies in Boston, MA at the age of 70. |
| Thursday, March 22 |
| Former Cardinal Lee DeMontreville dies in Pelham Manor, NY at the age of 87. |
| Tuesday, April 10 |
| » Major-league debuts: Joe Pepitone (Yankees) |
| Former Cardinal Milt Watson dies in Pine Bluff, AR at the age of 73. |
| Wednesday, April 11 |
| » Defeated Mets (0-1), 11-4 | Sportsman's Park III (1-0) | 1-0 | |
| » Starters: Roger Craig vs Larry Jackson | Second | ½ out |
| » Major-league debuts: Bob Moorhead (Mets) |
| Thursday, April 12 |
| » Major-league debuts: Diego Segui (Athletics) |
| Friday, April 13 |
| » Defeated Cubs (0-4), 8-5 | Wrigley Field (1-0) | 2-0 | Won 2 |
| » Starters: Ray Washburn vs Dick Ellsworth | Second | 1 out |
| » Major-league debuts: Morrie Steevens (Cubs) |
| Saturday, April 14 |
| » Defeated Cubs (0-5), 7-4 | Wrigley Field (2-0) | 3-0 | Won 3 |
| » Starters: Curt Simmons vs Don Cardwell | Second | 1 out |
| » Major-league debuts: Cal Koonce (Cubs) |
| Sunday, April 15 |
| » Major-league debuts: Bob Tillman (Red Sox) |
| Monday, April 16 |
| » Defeated Phillies (3-2), 12-6 | Shibe Park (1-0) | 4-0 | Won 4 |
| » Starters: Bob Gibson vs Cal McLish | Second | ½ out |
| Wednesday, April 18 |
| » Defeated Mets (0-6), 15-5 | Polo Grounds V (1-0) | 5-0 | Won 5 |
| » Starters: Larry Jackson vs Sherman Jones | Second | 1 out |
| Thursday, April 19 |
| » Defeated Mets (0-7), 9-4 | Polo Grounds V (2-0) | 6-0 | Won 6 |
| » Starters: Ray Washburn vs Al Jackson | Second | 1 out |
| Saturday, April 21 |
| » Defeated Cubs (1-9), 8-0 | Sportsman's Park III (2-0) | 7-0 | Won 7 |
| » Starters: Glen Hobbie vs Curt Simmons | Second | 1 out |
| Sunday, April 22 |
| » Lost to Cubs (2-9), 11-5 | Sportsman's Park III (2-1) | 7-1 | |
| » Starters: Dick Ellsworth vs Ray Sadecki | Second | 2½ out |
| » Lost to Cubs (3-9), 5-1 | Sportsman's Park III (2-2) | 7-2 | Lost 2 |
| » Starters: Cal Koonce vs Bob Gibson | Second | 2½ out |
| » Major-league debuts: Paul Toth (Cardinals) |
| Tuesday, April 24 |
| » Lost to Astros (6-5), 4-3 | Colt Stadium (0-1) | 7-3 | Lost 3 |
| » Starters: Larry Jackson vs Hal Woodeshick | Second | 3 out |
| Wednesday, April 25 |
| » Tied Astros, 5-5 | Colt Stadium (0-1) | 7-3 | |
| » Starters: Ray Washburn vs Dean Stone | Second | 2½ out |
| Thursday, April 26 |
| » Defeated Astros (6-6), 3-2 | Colt Stadium (1-1) | 8-3 | |
| » Starters: Bob Gibson vs Ken Johnson | Second | 2 out |
| Friday, April 27 |
| » Defeated Reds (7-9), 14-3 | Sportsman's Park III (3-2) | 9-3 | Won 2 |
| » Starters: Joey Jay vs Curt Simmons | Second | 1 out |
| Saturday, April 28 |
| » Defeated Reds (7-10), 5-4 | Sportsman's Park III (4-2) | 10-3 | Won 3 |
| » Starters: Jim O'Toole vs Ray Sadecki | First | -- |
| Sunday, April 29 |
| » Defeated Reds (7-11), 16-3 | Sportsman's Park III (5-2) | 11-3 | Won 4 |
| » Starters: Sammy Ellis vs Larry Jackson | Third | 1 out |
| » Lost to Reds (8-11), 4-3 | Sportsman's Park III (5-3) | 11-4 | |
| » Starters: Bob Purkey vs Ernie Broglio | Third | 1 out |
| Tuesday, May 1 |
| » Defeated Astros (7-9), 6-4 | Sportsman's Park III (6-3) | 12-4 | |
| » Starters: Dean Stone vs Ray Washburn | Second | 2½ out |
| Wednesday, May 2 |
| » Defeated Astros (7-10), 4-1 | Sportsman's Park III (7-3) | 13-4 | Won 2 |
| » Starters: Ken Johnson vs Bob Gibson | Second | 2½ out |
| Thursday, May 3 |
| » Defeated Astros (7-11), 4-0 | Sportsman's Park III (8-3) | 14-4 | Won 3 |
| » Starters: Dave Giusti vs Curt Simmons | Second | 2½ out |
| Friday, May 4 |
| » Lost to Reds (10-11), 3-2 | Crosley Field (0-1) | 14-5 | |
| » Starters: Larry Jackson vs Jim O'Toole | Second | 2½ out |
| Saturday, May 5 |
| » Lost to Reds (11-11), 8-7 | Crosley Field (0-2) | 14-6 | Lost 2 |
| » Starters: Ray Sadecki vs Bob Purkey | Second | 2½ out |
| Sunday, May 6 |
| » Lost to Reds (12-11), 5-4 | Crosley Field (0-3) | 14-7 | Lost 3 |
| » Starters: Ernie Broglio vs Joey Jay | Second | 3 out |
| » Defeated Reds (12-12), 3-0 | Crosley Field (1-3) | 15-7 | |
| » Starters: Bob Gibson vs Moe Drabowsky | Second | 3 out |
| Tuesday, May 8 |
| » Lost to Giants (21-6), 4-3 | Sportsman's Park III (8-4) | 15-8 | |
| » Starters: Juan Marichal vs Larry Jackson | Second | 4 out |
| Wednesday, May 9 |
| » Defeated Giants (21-7), 7-3 | Sportsman's Park III (9-4) | 16-8 | |
| » Starters: Jack Sanford vs Curt Simmons | Second | 3 out |
| Thursday, May 10 |
| » Lost to Giants (22-7), 6-0 | Sportsman's Park III (9-5) | 16-9 | |
| » Starters: Billy O'Dell vs Bob Gibson | Second | 4 out |
| Friday, May 11 |
| » Lost to Dodgers (19-11), 8-5 | Sportsman's Park III (9-6) | 16-10 | Lost 2 |
| » Starters: Stan Williams vs Ray Sadecki | Third | 4 out |
| Saturday, May 12 |
| » Defeated Dodgers (19-12), 6-5 | Sportsman's Park III (10-6) | 17-10 | |
| » Starters: Sandy Koufax vs Ernie Broglio | Second | 4 out |
| Sunday, May 13 |
| » Lost to Dodgers (20-12), 4-3 | Sportsman's Park III (10-7) | 17-11 | |
| » Starters: Johnny Podres vs Larry Jackson | Third | 5 out |
| Tuesday, May 15 |
| » Lost to Giants (25-8), 6-3 | Candlestick Park (0-1) | 17-12 | Lost 2 |
| » Starters: Curt Simmons vs Billy Pierce | Third | 6 out |
| Wednesday, May 16 |
| » Lost to Giants (26-8), 7-2 | Candlestick Park (0-2) | 17-13 | Lost 3 |
| » Starters: Ernie Broglio vs Juan Marichal | Fourth | 7 out |
| Thursday, May 17 |
| » Defeated Giants (26-9), 1-0 | Candlestick Park (1-2) | 18-13 | |
| » Starters: Bob Gibson vs Billy O'Dell | Third | 6 out |
| Future Cardinal Greg Mathews is born in Harbor City, CA. |
| Friday, May 18 |
| » Defeated Dodgers (23-13), 8-3 | Dodger Stadium (1-0) | 19-13 | Won 2 |
| » Starters: Larry Jackson vs Johnny Podres | Third | 5 out |
| Saturday, May 19 |
| » Defeated Dodgers (23-14), 8-1 | Dodger Stadium (2-0) | 20-13 | Won 3 |
| » Starters: Ray Sadecki vs Don Drysdale | Third | 5 out |
| Sunday, May 20 |
| » Defeated Dodgers (23-15), 4-3 | Dodger Stadium (3-0) | 21-13 | Won 4 |
| » Starters: Curt Simmons vs Joe Moeller | Second | 4½ out |
| Monday, May 21 |
| » Defeated Phillies (15-20), 4-1 | Sportsman's Park III (11-7) | 22-13 | Won 5 |
| » Starters: Dennis Bennett vs Ernie Broglio | Second | 3½ out |
| Tuesday, May 22 |
| » Defeated Phillies (15-21), 6-2 | Sportsman's Park III (12-7) | 23-13 | Won 6 |
| » Starters: Paul Brown vs Bob Gibson | Second | 2½ out |
| Wednesday, May 23 |
| » Lost to Pirates (19-17), 6-3 | Sportsman's Park III (12-8) | 23-14 | |
| » Starters: Harvey Haddix vs Larry Jackson | Third | 2½ out |
| Thursday, May 24 |
| » Lost to Pirates (20-17), 5-2 | Sportsman's Park III (12-9) | 23-15 | Lost 2 |
| » Starters: Al McBean vs Ray Sadecki | Third | 3½ out |
| Friday, May 25 |
| » Lost to Braves (18-23), 11-8 | Sportsman's Park III (12-10) | 23-16 | Lost 3 |
| » Starters: Jack Curtis vs Curt Simmons | Third | 4½ out |
| Saturday, May 26 |
| » Defeated Braves (18-24), 4-3 | Sportsman's Park III (13-10) | 24-16 | |
| » Starters: Carl Willey vs Larry Jackson | Third | 4½ out |
| Sunday, May 27 |
| » Lost to Braves (19-24), 4-3 | Sportsman's Park III (13-11) | 24-17 | |
| » Starters: Bob Shaw vs Bob Gibson | Fourth | 6 out |
| » Major-league debuts: Fred Whitfield (Cardinals) |
| Monday, May 28 |
| » Lost to Pirates (23-18), 3-1 | Forbes Field (0-1) | 24-18 | Lost 2 |
| » Starters: Ernie Broglio vs Harvey Haddix | Fourth | 6½ out |
| Former Cardinal George Anderson dies in Cleveland, OH at the age of 73. |
| Tuesday, May 29 |
| » Lost to Pirates (24-18), 7-6 | Forbes Field (0-2) | 24-19 | Lost 3 |
| » Starters: Ray Sadecki vs Al McBean | Fifth | 7 out |
| Future Cardinal Eric Davis is born in Los Angeles, CA. |
| Wednesday, May 30 |
| » Lost to Pirates (25-18), 3-1 | Forbes Field (0-3) | 24-20 | Lost 4 |
| » Starters: Ray Washburn vs Earl Francis | Fifth | 8½ out |
| Thursday, May 31 |
| » Lost to Pirates (26-18), 5-4 | Forbes Field (0-4) | 24-21 | Lost 5 |
| » Starters: Curt Simmons vs Bob Friend | Fifth | 8½ out |
| Friday, June 1 |
| » Lost to Braves (22-27), 7-0 | County Stadium (0-1) | 24-22 | Lost 6 |
| » Starters: Larry Jackson vs Bob Shaw | Fourth | 9½ out |
| Saturday, June 2 |
| » Lost to Braves (23-27), 4-1 | County Stadium (0-2) | 24-23 | Lost 7 |
| » Starters: Ernie Broglio vs Warren Spahn | Fifth | 11 out |
| Future Cardinal Darnell Coles is born in San Bernardino, CA. |
| Sunday, June 3 |
| » Lost to Braves (24-27), 6-4 | County Stadium (0-3) | 24-24 | Lost 8 |
| » Starters: Bob Gibson vs Bob Hendley | Fifth | 12 out |
| Tuesday, June 5 |
| » Defeated Reds (29-19), 10-9 | Sportsman's Park III (14-11) | 25-24 | |
| » Starters: Bob Purkey vs Curt Simmons | Fifth | 12 out |
| Wednesday, June 6 |
| » Defeated Reds (29-20), 4-3 | Sportsman's Park III (15-11) | 26-24 | Won 2 |
| » Starters: Joey Jay vs Larry Jackson | Fifth | 11 out |
| Thursday, June 7 |
| » Defeated Reds (29-21), 8-2 | Sportsman's Park III (16-11) | 27-24 | Won 3 |
| » Starters: Jim O'Toole vs Ernie Broglio | Fifth | 10 out |
| Friday, June 8 |
| » Defeated Giants (40-18), 8-4 | Sportsman's Park III (17-11) | 28-24 | Won 4 |
| » Starters: Juan Marichal vs Bob Gibson | Fifth | 9½ out |
| Saturday, June 9 |
| » Defeated Giants (40-19), 8-4 | Sportsman's Park III (18-11) | 29-24 | Won 5 |
| » Starters: Jack Sanford vs Ray Sadecki | Fourth | 8½ out |
| Sunday, June 10 |
| » Defeated Giants (40-20), 6-5 | Sportsman's Park III (19-11) | 30-24 | Won 6 |
| » Starters: Billy O'Dell vs Larry Jackson | Fourth | 8½ out |
| » Defeated Giants (40-21), 13-3 | Sportsman's Park III (20-11) | 31-24 | Won 7 |
| » Starters: Jim Duffalo vs Ray Washburn | Fourth | 8½ out |
| » Major-league debuts: Dal Maxvill (Cardinals) |
| Monday, June 11 |
| » Lost to Phillies (24-33), 8-5 | Sportsman's Park III (20-12) | 31-25 | |
| » Starters: Cal McLish vs Curt Simmons | Fifth | 9 out |
| Tuesday, June 12 |
| » Defeated Phillies (24-34), 3-2 | Sportsman's Park III (21-12) | 32-25 | |
| » Starters: Paul Brown vs Ernie Broglio | Fourth | 8 out |
| Wednesday, June 13 |
| » Defeated Phillies (24-35), 6-1 | Sportsman's Park III (22-12) | 33-25 | Won 2 |
| » Starters: Dennis Bennett vs Bob Gibson | Fourth | 8 out |
| Friday, June 15 |
| » Defeated Giants (42-24), 5-2 | Candlestick Park (2-2) | 34-25 | Won 3 |
| » Starters: Ray Sadecki vs Billy O'Dell | Fourth | 6½ out |
| Saturday, June 16 |
| » Lost to Giants (43-24), 5-0 | Candlestick Park (2-3) | 34-26 | |
| » Starters: Larry Jackson vs Juan Marichal | Fourth | 6½ out |
| Sunday, June 17 |
| » Lost to Giants (44-24), 6-3 | Candlestick Park (2-4) | 34-27 | Lost 2 |
| » Starters: Ernie Broglio vs Jack Sanford | Fourth | 7½ out |
| Monday, June 18 |
| » Lost to Dodgers (46-23), 1-0 | Dodger Stadium (3-1) | 34-28 | Lost 3 |
| » Starters: Bob Gibson vs Sandy Koufax | Fifth | 8½ out |
| Tuesday, June 19 |
| » Lost to Dodgers (47-23), 3-2 | Dodger Stadium (3-2) | 34-29 | Lost 4 |
| » Starters: Curt Simmons vs Don Drysdale | Fifth | 9½ out |
| Wednesday, June 20 |
| » Defeated Dodgers (47-24), 5-4 | Dodger Stadium (4-2) | 35-29 | |
| » Starters: Ray Sadecki vs Johnny Podres | Fifth | 8½ out |
| Friday, June 22 |
| » Defeated Phillies (28-37), 7-3 | Shibe Park (2-0) | 36-29 | Won 2 |
| » Starters: Larry Jackson vs Paul Brown | Fifth | 8 out |
| » Lost to Phillies (29-37), 11-3 | Shibe Park (2-1) | 36-30 | |
| » Starters: Ernie Broglio vs Jim Owens | Fifth | 8 out |
| Saturday, June 23 |
| » Defeated Phillies (29-38), 9-1 | Shibe Park (3-1) | 37-30 | |
| » Starters: Bob Gibson vs Bill Smith | Fourth | 8 out |
| Sunday, June 24 |
| » Lost to Phillies (30-38), 3-1 | Shibe Park (3-2) | 37-31 | |
| » Starters: Ray Sadecki vs Chris Short | Fifth | 7½ out |
| » Defeated Phillies (30-39), 5-1 | Shibe Park (4-2) | 38-31 | |
| » Starters: Curt Simmons vs Dennis Bennett | Fifth | 7½ out |
| Monday, June 25 |
| » Defeated Cubs (27-46), 6-4 | Wrigley Field (3-0) | 39-31 | Won 2 |
| » Starters: Ray Washburn vs Glen Hobbie | Fourth | 6½ out |
| Tuesday, June 26 |
| » Defeated Cubs (27-47), 15-3 | Wrigley Field (4-0) | 40-31 | Won 3 |
| » Starters: Ernie Broglio vs Dick Ellsworth | Fourth | 6 out |
| Wednesday, June 27 |
| » Defeated Cubs (27-48), 4-0 | Wrigley Field (5-0) | 41-31 | Won 4 |
| » Starters: Larry Jackson vs Don Cardwell | Fourth | 5½ out |
| » Defeated Cubs (27-49), 8-0 | Wrigley Field (6-0) | 42-31 | Won 5 |
| » Starters: Ray Sadecki vs Bob Anderson | Fourth | 5½ out |
| Thursday, June 28 |
| » Lost to Cubs (28-49), 7-2 | Wrigley Field (6-1) | 42-32 | |
| » Starters: Bob Gibson vs Cal Koonce | Fourth | 6 out |
| Friday, June 29 |
| » Defeated Pirates (43-32), 5-0 | Sportsman's Park III (23-12) | 43-32 | |
| » Starters: Harvey Haddix vs Curt Simmons | Third | 5½ out |
| Saturday, June 30 |
| » Lost to Pirates (44-32), 17-7 | Sportsman's Park III (23-13) | 43-33 | |
| » Starters: Vern Law vs Ray Washburn | Fourth | 6½ out |
| Sunday, July 1 |
| » Lost to Pirates (45-32), 7-2 | Sportsman's Park III (23-14) | 43-34 | Lost 2 |
| » Starters: Al McBean vs Larry Jackson | Fourth | 7½ out |
| Monday, July 2 |
| » Lost to Braves (39-39), 7-3 | Sportsman's Park III (23-15) | 43-35 | Lost 3 |
| » Starters: Lew Burdette vs Ray Sadecki | Fourth | 8½ out |
| Former Cardinal Josh Clarke dies in Ventura, CA at the age of 84. |
| Tuesday, July 3 |
| » Defeated Braves (39-40), 6-5 | Sportsman's Park III (24-15) | 44-35 | |
| » Starters: Bob Shaw vs Ray Washburn | Fourth | 8½ out |
| » Lost to Braves (40-40), 7-5 | Sportsman's Park III (24-16) | 44-36 | |
| » Starters: Tony Cloninger vs Bob Gibson | Fourth | 8½ out |
| Wednesday, July 4 |
| » Defeated Braves (40-41), 2-0 | Sportsman's Park III (25-16) | 45-36 | |
| » Starters: Warren Spahn vs Ernie Broglio | Fourth | 9 out |
| Friday, July 6 |
| » Lost to Mets (22-57), 10-3 | Polo Grounds V (2-1) | 45-37 | |
| » Starters: Ray Sadecki vs Roger Craig | Fourth | 9½ out |
| Saturday, July 7 |
| » Lost to Mets (23-57), 5-4 | Polo Grounds V (2-2) | 45-38 | Lost 2 |
| » Starters: Larry Jackson vs Al Jackson | Fifth | 9½ out |
| » Defeated Mets (23-58), 3-2 | Polo Grounds V (3-2) | 46-38 | |
| » Starters: Ray Washburn vs Craig Anderson | Fifth | 9½ out |
| Sunday, July 8 |
| » Defeated Mets (23-59), 15-1 | Polo Grounds V (4-2) | 47-38 | Won 2 |
| » Starters: Bob Gibson vs Jay Hook | Fifth | 9 out |
| Thursday, July 12 |
| » Lost to Braves (43-43), 8-6 | County Stadium (0-4) | 47-39 | |
| » Starters: Larry Jackson vs Bob Hendley | Fifth | 10 out |
| Friday, July 13 |
| » Defeated Braves (43-44), 6-0 | County Stadium (1-4) | 48-39 | |
| » Starters: Bob Gibson vs Warren Spahn | Fifth | 10 out |
| Saturday, July 14 |
| » Defeated Braves (43-45), 2-0 | County Stadium (2-4) | 49-39 | Won 2 |
| » Starters: Ernie Broglio vs Bob Shaw | Fourth | 10 out |
| Sunday, July 15 |
| » Defeated Pirates (55-35), 3-2 | Forbes Field (1-4) | 50-39 | Won 3 |
| » Starters: Ray Washburn vs Harvey Haddix | Fourth | 10 out |
| » Lost to Pirates (56-35), 8-7 | Forbes Field (1-5) | 50-40 | |
| » Starters: Curt Simmons vs Earl Francis | Fourth | 10 out |
| Monday, July 16 |
| » Lost to Pirates (57-35), 5-2 | Forbes Field (1-6) | 50-41 | Lost 2 |
| » Starters: Ray Sadecki vs Al McBean | Fourth | 10½ out |
| Tuesday, July 17 |
| » Defeated Cubs (35-59), 8-6 | Sportsman's Park III (26-16) | 51-41 | |
| » Starters: Don Cardwell vs Larry Jackson | Fourth | 9½ out |
| Wednesday, July 18 |
| » Defeated Cubs (35-60), 2-1 | Sportsman's Park III (27-16) | 52-41 | Won 2 |
| » Starters: Cal Koonce vs Bob Gibson | Fourth | 9½ out |
| Thursday, July 19 |
| » Defeated Cubs (35-61), 5-4 | Sportsman's Park III (28-16) | 53-41 | Won 3 |
| » Starters: Glen Hobbie vs Ernie Broglio | Fourth | 8½ out |
| Friday, July 20 |
| » Lost to Astros (35-58), 4-3 | Colt Stadium (1-2) | 53-42 | |
| » Starters: Ray Washburn vs Turk Farrell | Fourth | 9½ out |
| Saturday, July 21 |
| » Defeated Astros (35-59), 7-0 | Colt Stadium (2-2) | 54-42 | |
| » Starters: Larry Jackson vs Russ Kemmerer | Fifth | 10 out |
| » Lost to Astros (36-59), 7-3 | Colt Stadium (2-3) | 54-43 | |
| » Starters: Curt Simmons vs Ken Johnson | Fifth | 10 out |
| Sunday, July 22 |
| » Defeated Astros (36-60), 3-1 | Colt Stadium (3-3) | 55-43 | |
| » Starters: Bob Gibson vs Bob Bruce | Fifth | 10 out |
| Monday, July 23 |
| » Lost to Dodgers (67-34), 9-2 | Sportsman's Park III (28-17) | 55-44 | |
| » Starters: Johnny Podres vs Ray Sadecki | Fifth | 11 out |
| Former Cardinal Ralph Shinners dies in Milwaukee, WI at the age of 67. |
| Tuesday, July 24 |
| » Defeated Dodgers (67-35), 3-2 | Sportsman's Park III (29-17) | 56-44 | |
| » Starters: Stan Williams vs Ernie Broglio | Fifth | 10 out |
| Wednesday, July 25 |
| » Lost to Dodgers (68-35), 5-2 | Sportsman's Park III (29-18) | 56-45 | |
| » Starters: Don Drysdale vs Ray Washburn | Fifth | 11 out |
| Friday, July 27 |
| » Lost to Mets (25-73), 1-0 | Sportsman's Park III (29-19) | 56-46 | Lost 2 |
| » Starters: Al Jackson vs Bob Gibson | Fifth | 11½ out |
| » Defeated Mets (25-74), 6-5 | Sportsman's Park III (30-19) | 57-46 | |
| » Starters: Bob Moorhead vs Larry Jackson | Fifth | 11½ out |
| Saturday, July 28 |
| » Lost to Mets (26-74), 9-8 | Sportsman's Park III (30-20) | 57-47 | |
| » Starters: Jay Hook vs Ray Sadecki | Fifth | 12½ out |
| Sunday, July 29 |
| » Defeated Mets (26-75), 6-5 | Sportsman's Park III (31-20) | 58-47 | |
| » Starters: Bob Miller vs Ernie Broglio | Fifth | 12 out |
| » Defeated Mets (26-76), 5-1 | Sportsman's Park III (32-20) | 59-47 | Won 2 |
| » Starters: Roger Craig vs Ray Washburn | Fifth | 12 out |
| Former Cardinal Burt Shotton dies in Lake Wales, FL at the age of 78. |
| Monday, July 30 |
| Future Cardinal Tom Pagnozzi is born in Tucson, AZ. |
| Wednesday, August 1 |
| » Lost to Reds (62-42), 5-1 | Crosley Field (1-4) | 59-48 | |
| » Starters: Larry Jackson vs Jim O'Toole | Fifth | 12 out |
| Thursday, August 2 |
| » Defeated Reds (62-43), 5-1 | Crosley Field (2-4) | 60-48 | |
| » Starters: Ernie Broglio vs Bob Purkey | Fifth | 12 out |
| Friday, August 3 |
| » Lost to Astros (39-66), 8-3 | Sportsman's Park III (32-21) | 60-49 | |
| » Starters: Ken Johnson vs Bob Gibson | Fifth | 13 out |
| Saturday, August 4 |
| » Defeated Astros (39-67), 2-0 | Sportsman's Park III (33-21) | 61-49 | |
| » Starters: Bob Bruce vs Ray Washburn | Fifth | 13 out |
| Sunday, August 5 |
| » Lost to Astros (40-67), 7-4 | Sportsman's Park III (33-22) | 61-50 | |
| » Starters: George Brunet vs Larry Jackson | Fifth | 13 out |
| » Defeated Astros (40-68), 7-4 | Sportsman's Park III (34-22) | 62-50 | |
| » Starters: Hal Woodeshick vs Paul Toth | Fifth | 13 out |
| Tuesday, August 7 |
| » Defeated Pirates (63-48), 5-0 | Forbes Field (2-6) | 63-50 | Won 2 |
| » Starters: Ernie Broglio vs Joe Gibbon | Fifth | 13½ out |
| Wednesday, August 8 |
| » Defeated Pirates (63-49), 2-0 | Forbes Field (3-6) | 64-50 | Won 3 |
| » Starters: Bob Gibson vs Al McBean | Fifth | 13½ out |
| Friday, August 10 |
| » Defeated Phillies (51-66), 7-4 | Sportsman's Park III (35-22) | 65-50 | Won 4 |
| » Starters: Jim Owens vs Ray Washburn | Fourth | 13 out |
| Saturday, August 11 |
| » Lost to Phillies (52-66), 11-3 | Sportsman's Park III (35-23) | 65-51 | |
| » Starters: Art Mahaffey vs Larry Jackson | Fifth | 13 out |
| Sunday, August 12 |
| » Lost to Phillies (53-66), 7-3 | Sportsman's Park III (35-24) | 65-52 | Lost 2 |
| » Starters: Cal McLish vs Ernie Broglio | Fifth | 13½ out |
| » Lost to Phillies (54-66), 9-7 | Sportsman's Park III (35-25) | 65-53 | Lost 3 |
| » Starters: Jack Hamilton vs Curt Simmons | Fifth | 13½ out |
| Tuesday, August 14 |
| » Lost to Astros (42-74), 4-3 | Colt Stadium (3-4) | 65-54 | Lost 4 |
| » Starters: Bob Gibson vs Ken Johnson | Fifth | 13½ out |
| Wednesday, August 15 |
| » Lost to Astros (43-74), 3-1 | Colt Stadium (3-5) | 65-55 | Lost 5 |
| » Starters: Ray Washburn vs Hal Woodeshick | Fifth | 13½ out |
| Thursday, August 16 |
| » Defeated Astros (43-75), 3-1 | Colt Stadium (4-5) | 66-55 | |
| » Starters: Larry Jackson vs Turk Farrell | Fifth | 13½ out |
| Saturday, August 18 |
| » Defeated Mets (30-90), 7-4 | Polo Grounds V (5-2) | 67-55 | Won 2 |
| » Starters: Ernie Broglio vs Roger Craig | Fifth | 12½ out |
| » Defeated Mets (30-91), 10-0 | Polo Grounds V (6-2) | 68-55 | Won 3 |
| » Starters: Bob Gibson vs Ken MacKenzie | Fifth | 12½ out |
| Sunday, August 19 |
| » Defeated Mets (30-92), 10-5 | Polo Grounds V (7-2) | 69-55 | Won 4 |
| » Starters: Lindy McDaniel vs Al Jackson | Fifth | 12½ out |
| Tuesday, August 21 |
| » Lost to Braves (68-59), 6-5 | County Stadium (2-5) | 69-56 | |
| » Starters: Larry Jackson vs Denny Lemaster | Fifth | 12½ out |
| Wednesday, August 22 |
| » Lost to Braves (69-59), 6-4 | County Stadium (2-6) | 69-57 | Lost 2 |
| » Starters: Ray Washburn vs Bob Shaw | Fifth | 12½ out |
| Thursday, August 23 |
| » Lost to Braves (70-59), 3-2 | County Stadium (2-7) | 69-58 | Lost 3 |
| » Starters: Ernie Broglio vs Bob Hendley | Sixth | 13½ out |
| Saturday, August 25 |
| » Defeated Pirates (74-54), 3-2 | Sportsman's Park III (36-25) | 70-58 | |
| » Starters: Bob Friend vs Larry Jackson | Fifth | 13½ out |
| » Lost to Pirates (75-54), 4-0 | Sportsman's Park III (36-26) | 70-59 | |
| » Starters: Earl Francis vs Curt Simmons | Fifth | 13½ out |
| » Major-league debuts: Bob Burda (Cardinals) |
| Sunday, August 26 |
| » Defeated Pirates (75-55), 6-5 | Sportsman's Park III (37-26) | 71-59 | |
| » Starters: Harvey Haddix vs Ray Washburn | Fifth | 14 out |
| » Lost to Pirates (76-55), 7-6 | Sportsman's Park III (37-27) | 71-60 | |
| » Starters: Tom Sturdivant vs Lindy McDaniel | Fifth | 14 out |
| Tuesday, August 28 |
| » Lost to Astros (48-84), 4-2 | Sportsman's Park III (37-28) | 71-61 | Lost 2 |
| » Starters: Bob Bruce vs Ernie Broglio | Fifth | 15 out |
| Wednesday, August 29 |
| » Lost to Astros (49-84), 3-2 | Sportsman's Park III (37-29) | 71-62 | Lost 3 |
| » Starters: Turk Farrell vs Bob Gibson | Sixth | 16 out |
| Friday, August 31 |
| » Defeated Mets (34-102), 4-2 | Sportsman's Park III (38-29) | 72-62 | |
| » Starters: Craig Anderson vs Larry Jackson | Fifth | 15½ out |
| Saturday, September 1 |
| » Defeated Mets (34-103), 10-5 | Sportsman's Park III (39-29) | 73-62 | Won 2 |
| » Starters: Ray Daviault vs Ray Washburn | Fifth | 15½ out |
| Sunday, September 2 |
| » Lost to Mets (35-103), 4-3 | Sportsman's Park III (39-30) | 73-63 | |
| » Starters: Al Jackson vs Ernie Broglio | Fifth | 16½ out |
| Monday, September 3 |
| » Lost to Cubs (51-86), 6-2 | Sportsman's Park III (39-31) | 73-64 | Lost 2 |
| » Starters: Glen Hobbie vs Bob Gibson | Fifth | 17 out |
| » Lost to Cubs (52-86), 5-2 | Sportsman's Park III (39-32) | 73-65 | Lost 3 |
| » Starters: Don Cardwell vs Curt Simmons | Fifth | 17 out |
| Tuesday, September 4 |
| » Defeated Cubs (52-87), 7-1 | Sportsman's Park III (40-32) | 74-65 | |
| » Starters: Cal Koonce vs Larry Jackson | Fifth | 17 out |
| Wednesday, September 5 |
| » Lost to Braves (73-68), 1-0 | Sportsman's Park III (40-33) | 74-66 | |
| » Starters: Tony Cloninger vs Ray Washburn | Fifth | 17 out |
| Thursday, September 6 |
| » Defeated Braves (73-69), 7-1 | Sportsman's Park III (41-33) | 75-66 | |
| » Starters: Denny Lemaster vs Ernie Broglio | Fifth | 16 out |
| Friday, September 7 |
| » Lost to Reds (88-55), 6-5 | Crosley Field (2-5) | 75-67 | |
| » Starters: Bob Gibson vs Bob Purkey | Fifth | 16 out |
| Saturday, September 8 |
| » Defeated Reds (88-56), 5-4 | Crosley Field (3-5) | 76-67 | |
| » Starters: Larry Jackson vs Joey Jay | Fifth | 16 out |
| Sunday, September 9 |
| » Defeated Reds (88-57), 5-3 | Crosley Field (4-5) | 77-67 | Won 2 |
| » Starters: Ray Washburn vs Jim O'Toole | Fifth | 16 out |
| Monday, September 10 |
| » Lost to Reds (89-57), 4-3 | Sportsman's Park III (41-34) | 77-68 | |
| » Starters: Joe Nuxhall vs Ernie Broglio | Fifth | 17 out |
| Tuesday, September 11 |
| » Lost to Reds (90-57), 6-2 | Sportsman's Park III (41-35) | 77-69 | Lost 2 |
| » Starters: Bob Purkey vs Bob Gibson | Fifth | 18 out |
| » Major-league debuts: Mike Shannon (Cardinals) |
| Friday, September 14 |
| » Lost to Phillies (73-76), 2-1 | Shibe Park (4-3) | 77-70 | Lost 3 |
| » Starters: Larry Jackson vs Dennis Bennett | Fifth | 19½ out |
| Saturday, September 15 |
| » Lost to Phillies (74-76), 5-4 | Shibe Park (4-4) | 77-71 | Lost 4 |
| » Starters: Ernie Broglio vs Jack Hamilton | Fifth | 20½ out |
| » Major-league debuts: John Herrnstein (Phillies) |
| Sunday, September 16 |
| » Lost to Phillies (75-76), 3-1 | Shibe Park (4-5) | 77-72 | Lost 5 |
| » Starters: Bob Gibson vs Art Mahaffey | Sixth | 20½ out |
| Monday, September 17 |
| » Lost to Cubs (54-96), 8-4 | Wrigley Field (6-2) | 77-73 | Lost 6 |
