| Sunday, January 29 |
| Future Giant Mike Aldrete is born in Carmel, CA. |
| Wednesday, March 29 |
| Future Giant Mike Kingery is born in St. James, MN. |
| Friday, March 31 |
| Future Giant Tracy Jones is born in Hawthorne, CA. |
| Tuesday, April 4 |
| Future Giant Brad Komminsk is born in Lima, OH. |
| Tuesday, April 11 |
| » Lost to Pirates (1-0), 8-7 | Candlestick Park (0-1) | 0-1 | |
| » Starters: Bob Friend vs Sam Jones | Second | 1 out |
| » Major-league debuts: Tom Haller and Chuck Hiller (Giants) |
| Wednesday, April 12 |
| » Defeated Pirates (1-1), 2-1 | Candlestick Park (1-1) | 1-1 | |
| » Starters: Vern Law vs Billy Loes | Third | 1 out |
| » Major-league debuts: Jim Duffalo (Giants) |
| Thursday, April 13 |
| » Defeated Pirates (1-2), 6-5 | Candlestick Park (2-1) | 2-1 | Won 2 |
| » Starters: Harvey Haddix vs Jack Sanford | Second | ½ out |
| Friday, April 14 |
| » Defeated Phillies (1-3), 2-0 | Candlestick Park (3-1) | 3-1 | Won 3 |
| » Starters: Art Mahaffey vs Mike McCormick | Second | ½ out |
| Saturday, April 15 |
| » Lost to Phillies (2-3), 2-0 | Candlestick Park (3-2) | 3-2 | |
| » Starters: Dallas Green vs Juan Marichal | Second | ½ out |
| » Major-league debuts: Bob Farley (Giants) |
| Sunday, April 16 |
| » Defeated Phillies (2-4), 5-2 | Candlestick Park (4-2) | 4-2 | |
| » Starters: Robin Roberts vs Sam Jones | First | -- |
| » Major-league debuts: Choo Choo Coleman (Phillies) |
| Tuesday, April 18 |
| » Lost to Reds (4-2), 9-1 | Candlestick Park (4-3) | 4-3 | |
| » Starters: Bob Purkey vs Billy Loes | Second | ½ out |
| » Major-league debuts: Bobby Bolin (Giants) |
| Wednesday, April 19 |
| » Lost to Reds (5-2), 4-2 | Candlestick Park (4-4) | 4-4 | Lost 2 |
| » Starters: Ken Hunt vs Jack Sanford | Fourth | 1½ out |
| Thursday, April 20 |
| » Defeated Reds (5-3), 2-1 | Candlestick Park (5-4) | 5-4 | |
| » Starters: Jim O'Toole vs Mike McCormick | Second | ½ out |
| Saturday, April 22 |
| » Major-league debuts: Jack Curtis (Cubs) |
| Sunday, April 23 |
| » Defeated Cardinals (5-5), 2-1 | Candlestick Park (6-4) | 6-4 | Won 2 |
| » Starters: Ernie Broglio vs Sam Jones | Second | 1 out |
| » Lost to Cardinals (6-5), 7-4 | Candlestick Park (6-5) | 6-5 | |
| » Starters: Bob Gibson vs Billy Loes | Second | 1 out |
| Tuesday, April 25 |
| » Defeated Dodgers (8-6), 3-1 | Los Angeles Memorial Coliseum (1-0) | 7-5 | |
| » Starters: Jack Sanford vs Don Drysdale | First | -- |
| Wednesday, April 26 |
| » Defeated Dodgers (8-7), 6-5 | Los Angeles Memorial Coliseum (2-0) | 8-5 | Won 2 |
| » Starters: Mike McCormick vs Stan Williams | First | -- |
| Friday, April 28 |
| » Lost to Braves (6-4), 1-0 | County Stadium (0-1) | 8-6 | |
| » Starters: Sam Jones vs Warren Spahn | Third | 2 out |
| Saturday, April 29 |
| » Defeated Braves (6-5), 7-3 | County Stadium (1-1) | 9-6 | |
| » Starters: Juan Marichal vs Bob Buhl | Second | 1 out |
| » Major-league debuts: Phil Roof (Braves) |
| Sunday, April 30 |
| » Defeated Braves (6-6), 14-4 | County Stadium (2-1) | 10-6 | Won 2 |
| » Starters: Billy Loes vs Lew Burdette | First | -- |
| Tuesday, May 2 |
| » Lost to Cubs (9-8), 9-4 | Wrigley Field (0-1) | 10-7 | |
| » Starters: Jack Sanford vs Don Cardwell | Second | ½ out |
| Wednesday, May 3 |
| » Defeated Cubs (9-9), 8-4 | Wrigley Field (1-1) | 11-7 | |
| » Starters: Mike McCormick vs Jack Curtis | First | -- |
| Thursday, May 4 |
| » Defeated Cubs (9-10), 9-3 | Wrigley Field (2-1) | 12-7 | Won 2 |
| » Starters: Sam Jones vs Glen Hobbie | First | -- |
| Friday, May 5 |
| » Defeated Phillies (6-14), 4-2 | Shibe Park (1-0) | 13-7 | Won 3 |
| » Starters: Juan Marichal vs Frank Sullivan | First | -- |
| Sunday, May 7 |
| » Defeated Phillies (6-15), 7-0 | Shibe Park (2-0) | 14-7 | Won 4 |
| » Starters: Billy Loes vs Robin Roberts | First | -- |
| Tuesday, May 9 |
| » Lost to Pirates (12-9), 9-6 | Forbes Field (0-1) | 14-8 | |
| » Starters: Jack Sanford vs Harvey Haddix | First | -- |
| Wednesday, May 10 |
| » Defeated Pirates (12-10), 3-0 | Forbes Field (1-1) | 15-8 | |
| » Starters: Mike McCormick vs Bob Friend | First | -- |
| Friday, May 12 |
| » Lost to Braves (11-10), 5-4 | Candlestick Park (6-6) | 15-9 | |
| » Starters: Warren Spahn vs Sam Jones | First | -- |
| Saturday, May 13 |
| » Defeated Braves (11-11), 8-5 | Candlestick Park (7-6) | 16-9 | |
| » Starters: Bob Buhl vs Juan Marichal | First | -- |
| Sunday, May 14 |
| » Defeated Braves (11-12), 8-7 | Candlestick Park (8-6) | 17-9 | Won 2 |
| » Starters: Carl Willey vs Billy Loes | First | -- |
| Monday, May 15 |
| » Defeated Cubs (10-17), 14-1 | Candlestick Park (9-6) | 18-9 | Won 3 |
| » Starters: Dick Ellsworth vs Mike McCormick | First | -- |
| Tuesday, May 16 |
| » Defeated Cubs (10-18), 2-1 | Candlestick Park (10-6) | 19-9 | Won 4 |
| » Starters: Dick Drott vs Jack Sanford | First | -- |
| Wednesday, May 17 |
| » Defeated Cubs (10-19), 4-3 | Candlestick Park (11-6) | 20-9 | Won 5 |
| » Starters: Don Cardwell vs Sam Jones | First | -- |
| Friday, May 19 |
| » Lost to Dodgers (20-14), 8-7 | Candlestick Park (11-7) | 20-10 | |
| » Starters: Don Drysdale vs Juan Marichal | First | -- |
| Saturday, May 20 |
| » Lost to Dodgers (21-14), 4-3 | Candlestick Park (11-8) | 20-11 | Lost 2 |
| » Starters: Roger Craig vs Mike McCormick | First | -- |
| Sunday, May 21 |
| » Lost to Dodgers (22-14), 3-2 | Candlestick Park (11-9) | 20-12 | Lost 3 |
| » Starters: Sandy Koufax vs Billy Loes | First | -- |
| Monday, May 22 |
| » Defeated Cardinals (13-18), 3-1 | Sportsman's Park III (1-0) | 21-12 | |
| » Starters: Jack Sanford vs Ernie Broglio | First | -- |
| Tuesday, May 23 |
| » Lost to Cardinals (14-18), 12-4 | Sportsman's Park III (1-1) | 21-13 | |
| » Starters: Sam Jones vs Ray Sadecki | First | -- |
| Wednesday, May 24 |
| » Defeated Reds (20-16), 5-4 | Crosley Field (1-0) | 22-13 | |
| » Starters: Mike McCormick vs Jim O'Toole | First | -- |
| Friday, May 26 |
| » Defeated Cubs (12-24), 3-2 | Wrigley Field (3-1) | 23-13 | Won 2 |
| » Starters: Juan Marichal vs Don Cardwell | First | -- |
| Saturday, May 27 |
| » Defeated Cubs (12-25), 8-2 | Wrigley Field (4-1) | 24-13 | Won 3 |
| » Starters: Billy Loes vs Dick Drott | First | -- |
| Sunday, May 28 |
| » Defeated Cubs (12-26), 6-5 | Wrigley Field (5-1) | 25-13 | Won 4 |
| » Starters: Jack Sanford vs Glen Hobbie | First | -- |
| Monday, May 29 |
| » Lost to Reds (23-16), 5-1 | Candlestick Park (11-10) | 25-14 | |
| » Starters: Ken Hunt vs Mike McCormick | First | -- |
| Tuesday, May 30 |
| » Lost to Reds (24-16), 7-6 | Candlestick Park (11-11) | 25-15 | Lost 2 |
| » Starters: Jim Maloney vs Sam Jones | First | -- |
| » Lost to Reds (25-16), 6-4 | Candlestick Park (11-12) | 25-16 | Lost 3 |
| » Starters: Jim O'Toole vs Juan Marichal | First | -- |
| Wednesday, May 31 |
| » Defeated Cardinals (18-22), 3-2 | Candlestick Park (12-12) | 26-16 | |
| » Starters: Curt Simmons vs Billy O'Dell | First | -- |
| Thursday, June 1 |
| » Lost to Cardinals (19-22), 7-6 | Candlestick Park (12-13) | 26-17 | |
| » Starters: Ernie Broglio vs Mike McCormick | Second | ½ out |
| Friday, June 2 |
| » Lost to Dodgers (28-19), 6-2 | Los Angeles Memorial Coliseum (2-1) | 26-18 | Lost 2 |
| » Starters: Jack Sanford vs Roger Craig | Third | ½ out |
| Saturday, June 3 |
| » Lost to Dodgers (29-19), 4-3 | Los Angeles Memorial Coliseum (2-2) | 26-19 | Lost 3 |
| » Starters: Juan Marichal vs Sandy Koufax | Third | 1½ out |
| Sunday, June 4 |
| » Defeated Dodgers (29-20), 4-2 | Los Angeles Memorial Coliseum (3-2) | 27-19 | |
| » Starters: Sam Jones vs Stan Williams | Second | 1½ out |
| Monday, June 5 |
| » Lost to Phillies (15-29), 3-2 | Candlestick Park (12-14) | 27-20 | |
| » Starters: Robin Roberts vs Mike McCormick | Third | 1 out |
| Tuesday, June 6 |
| » Lost to Phillies (16-29), 13-9 | Candlestick Park (12-15) | 27-21 | Lost 2 |
| » Starters: Frank Sullivan vs Billy O'Dell | Third | 2 out |
| Wednesday, June 7 |
| » Defeated Phillies (16-30), 4-3 | Candlestick Park (13-15) | 28-21 | |
| » Starters: Art Mahaffey vs Jack Sanford | Third | 1½ out |
| Thursday, June 8 |
| » Lost to Phillies (17-30), 5-2 | Candlestick Park (13-16) | 28-22 | |
| » Starters: John Buzhardt vs Sam Jones | Third | 2 out |
| Friday, June 9 |
| » Defeated Pirates (25-23), 9-6 | Candlestick Park (14-16) | 29-22 | |
| » Starters: Harvey Haddix vs Juan Marichal | Third | 1½ out |
| Saturday, June 10 |
| » Defeated Pirates (25-24), 5-0 | Candlestick Park (15-16) | 30-22 | Won 2 |
| » Starters: Vinegar Bend Mizell vs Mike McCormick | Third | 1½ out |
| Sunday, June 11 |
| » Lost to Pirates (26-24), 8-4 | Candlestick Park (15-17) | 30-23 | |
| » Starters: Vern Law vs Billy Loes | Third | 2½ out |
| Monday, June 12 |
| » Defeated Dodgers (34-23), 7-4 | Candlestick Park (16-17) | 31-23 | |
| » Starters: Roger Craig vs Jack Sanford | Third | 2 out |
| Tuesday, June 13 |
| » Defeated Dodgers (34-24), 4-3 | Candlestick Park (17-17) | 32-23 | Won 2 |
| » Starters: Stan Williams vs Sam Jones | Third | 1 out |
| » Major-league debuts: Dick LeMay (Giants) |
| Wednesday, June 14 |
| » Defeated Braves (24-28), 11-2 | Candlestick Park (18-17) | 33-23 | Won 3 |
| » Starters: Warren Spahn vs Juan Marichal | Second | 1½ out |
| Thursday, June 15 |
| » Defeated Braves (24-29), 6-3 | Candlestick Park (19-17) | 34-23 | Won 4 |
| » Starters: Tony Cloninger vs Mike McCormick | Second | 1½ out |
| » Major-league debuts: Tony Cloninger (Braves) |
| Friday, June 16 |
| » Lost to Cubs (22-34), 12-6 | Candlestick Park (19-18) | 34-24 | |
| » Starters: Dick Ellsworth vs Billy Loes | Third | 1 out |
| Saturday, June 17 |
| » Defeated Cubs (22-35), 9-3 | Candlestick Park (20-18) | 35-24 | |
| » Starters: Jack Curtis vs Billy O'Dell | Third | 1 out |
| Sunday, June 18 |
| » Defeated Cubs (22-36), 7-2 | Candlestick Park (21-18) | 36-24 | Won 2 |
| » Starters: Don Cardwell vs Juan Marichal | Second | 1½ out |
| Tuesday, June 20 |
| » Lost to Braves (27-30), 2-1 | County Stadium (2-2) | 36-25 | |
| » Starters: Mike McCormick vs Warren Spahn | Third | 2 out |
| Wednesday, June 21 |
| » Lost to Braves (28-30), 5-3 | County Stadium (2-3) | 36-26 | Lost 2 |
| » Starters: Jack Sanford vs Lew Burdette | Third | 3 out |
| Thursday, June 22 |
| » Lost to Braves (29-30), 8-6 | County Stadium (2-4) | 36-27 | Lost 3 |
| » Starters: Juan Marichal vs Bob Buhl | Third | 4 out |
| Friday, June 23 |
| » Lost to Cardinals (29-33), 10-5 | Sportsman's Park III (1-2) | 36-28 | Lost 4 |
| » Starters: Billy O'Dell vs Curt Simmons | Third | 5 out |
| » Major-league debuts: Craig Anderson (Cardinals) |
| Saturday, June 24 |
| » Defeated Cardinals (29-34), 6-1 | Sportsman's Park III (2-2) | 37-28 | |
| » Starters: Dick LeMay vs Bob Gibson | Third | 4 out |
| Sunday, June 25 |
| » Defeated Cardinals (29-35), 6-4 | Sportsman's Park III (3-2) | 38-28 | Won 2 |
| » Starters: Mike McCormick vs Bob Miller | Third | 4½ out |
| » Lost to Cardinals (30-35), 3-1 | Sportsman's Park III (3-3) | 38-29 | |
| » Starters: Billy Loes vs Ray Sadecki | Third | 4½ out |
| Monday, June 26 |
| » Lost to Phillies (22-41), 1-0 | Shibe Park (2-1) | 38-30 | Lost 2 |
| » Starters: Jack Sanford vs Jim Owens | Third | 5 out |
| Tuesday, June 27 |
| » Defeated Phillies (22-42), 12-5 | Shibe Park (3-1) | 39-30 | |
| » Starters: Juan Marichal vs John Buzhardt | Third | 5 out |
| Wednesday, June 28 |
| » Tied Phillies, 7-7 | Shibe Park (3-1) | 39-30 | |
| » Starters: Dick LeMay vs Chris Short | Third | 4 out |
| Thursday, June 29 |
| » Defeated Phillies (22-43), 8-7 | Shibe Park (4-1) | 40-30 | Won 2 |
| » Starters: Billy O'Dell vs Ken Lehman | Second | 2½ out |
| » Defeated Phillies (22-44), 4-1 | Shibe Park (5-1) | 41-30 | Won 3 |
| » Starters: Billy Loes vs Art Mahaffey | Second | 2½ out |
| Friday, June 30 |
| » Lost to Pirates (36-31), 4-3 | Forbes Field (1-2) | 41-31 | |
| » Starters: Mike McCormick vs Harvey Haddix | Third | 3½ out |
| Saturday, July 1 |
| » Defeated Pirates (36-32), 4-3 | Forbes Field (2-2) | 42-31 | |
| » Starters: Jack Sanford vs Bob Friend | Third | 2½ out |
| Sunday, July 2 |
| » Lost to Pirates (37-32), 7-6 | Forbes Field (2-3) | 42-32 | |
| » Starters: Dick LeMay vs Vern Law | Third | 4½ out |
| » Lost to Pirates (38-32), 9-0 | Forbes Field (2-4) | 42-33 | Lost 2 |
| » Starters: Juan Marichal vs Bobby Shantz | Third | 4½ out |
| » Major-league debuts: Al McBean (Pirates) |
| Tuesday, July 4 |
| » Defeated Cubs (30-43), 19-3 | Wrigley Field (6-1) | 43-33 | |
| » Starters: Eddie Fisher vs Don Cardwell | Third | 5½ out |
| » Lost to Cubs (31-43), 3-2 | Wrigley Field (6-2) | 43-34 | |
| » Starters: Billy Loes vs Jack Curtis | Third | 5½ out |
| Wednesday, July 5 |
| » Lost to Reds (50-29), 3-2 | Candlestick Park (21-19) | 43-35 | Lost 2 |
| » Starters: Sherman Jones vs Mike McCormick | Third | 6½ out |
| Thursday, July 6 |
| » Lost to Reds (51-29), 3-2 | Candlestick Park (21-20) | 43-36 | Lost 3 |
| » Starters: Jim O'Toole vs Juan Marichal | Third | 7½ out |
| Friday, July 7 |
| » Lost to Cardinals (34-42), 3-2 | Candlestick Park (21-21) | 43-37 | Lost 4 |
| » Starters: Al Cicotte vs Billy Loes | Third | 9 out |
| Saturday, July 8 |
| » Lost to Cardinals (35-42), 9-7 | Candlestick Park (21-22) | 43-38 | Lost 5 |
| » Starters: Larry Jackson vs Dick LeMay | Fourth | 9 out |
| Sunday, July 9 |
| » Lost to Cardinals (36-42), 6-3 | Candlestick Park (21-23) | 43-39 | Lost 6 |
| » Starters: Curt Simmons vs Billy O'Dell | Fourth | 9½ out |
| » Defeated Cardinals (36-43), 6-1 | Candlestick Park (22-23) | 44-39 | |
| » Starters: Ray Sadecki vs Jack Sanford | Fourth | 9½ out |
| Thursday, July 13 |
| » Defeated Pirates (42-36), 2-1 | Candlestick Park (23-23) | 45-39 | Won 2 |
| » Starters: Bob Friend vs Billy O'Dell | Fourth | 9½ out |
| Friday, July 14 |
| » Lost to Pirates (43-36), 6-4 | Candlestick Park (23-24) | 45-40 | |
| » Starters: Joe Gibbon vs Jack Sanford | Fourth | 9½ out |
| » Major-league debuts: John Orsino (Giants) |
| Saturday, July 15 |
| » Defeated Pirates (43-37), 8-3 | Candlestick Park (24-24) | 46-40 | |
| » Starters: Harvey Haddix vs Mike McCormick | Fourth | 9½ out |
| Sunday, July 16 |
| » Defeated Phillies (25-57), 7-3 | Candlestick Park (25-24) | 47-40 | Won 2 |
| » Starters: Jim Owens vs Sam Jones | Third | 8½ out |
| » Major-league debuts: George Williams (Phillies) |
| Monday, July 17 |
| » Lost to Phillies (26-57), 10-7 | Candlestick Park (25-25) | 47-41 | |
| » Starters: Dallas Green vs Billy O'Dell | Third | 8½ out |
| Wednesday, July 19 |
| » Lost to Cardinals (43-45), 3-2 | Sportsman's Park III (3-4) | 47-42 | Lost 2 |
| » Starters: Mike McCormick vs Ray Sadecki | Third | 8 out |
| Thursday, July 20 |
| » Defeated Cardinals (43-46), 10-6 | Sportsman's Park III (4-4) | 48-42 | |
| » Starters: Sam Jones vs Al Cicotte | Third | 7 out |
| Saturday, July 22 |
| » Defeated Reds (56-37), 8-3 | Crosley Field (2-0) | 49-42 | Won 2 |
| » Starters: Jack Sanford vs Ken Hunt | Third | 6 out |
| Sunday, July 23 |
| » Lost to Reds (57-37), 6-5 | Crosley Field (2-1) | 49-43 | |
| » Starters: Juan Marichal vs Bob Purkey | Third | 8 out |
| » Lost to Reds (58-37), 11-2 | Crosley Field (2-2) | 49-44 | Lost 2 |
| » Starters: Billy O'Dell vs Jim O'Toole | Third | 8 out |
| Tuesday, July 25 |
| » Defeated Pirates (44-44), 16-7 | Forbes Field (3-4) | 50-44 | |
| » Starters: Mike McCormick vs Joe Gibbon | Third | 7½ out |
| Wednesday, July 26 |
| » Lost to Pirates (45-44), 8-3 | Forbes Field (3-5) | 50-45 | |
| » Starters: Jack Sanford vs Bob Friend | Third | 8½ out |
| Thursday, July 27 |
| » Defeated Pirates (45-45), 2-0 | Forbes Field (4-5) | 51-45 | |
| » Starters: Juan Marichal vs Vinegar Bend Mizell | Third | 8½ out |
| Friday, July 28 |
| » Defeated Phillies (29-64), 8-5 | Shibe Park (6-1) | 52-45 | Won 2 |
| » Starters: Bobby Bolin vs Art Mahaffey | Third | 9 out |
| » Lost to Phillies (30-64), 4-3 | Shibe Park (6-2) | 52-46 | |
| » Starters: Billy Loes vs John Buzhardt | Third | 9 out |
| Saturday, July 29 |
| » Defeated Phillies (30-65), 4-3 | Shibe Park (7-2) | 53-46 | |
| » Starters: Mike McCormick vs Don Ferrarese | Third | 8 out |
| Sunday, July 30 |
| » Defeated Phillies (30-66), 5-2 | Shibe Park (8-2) | 54-46 | Won 2 |
| » Starters: Jack Sanford vs Jim Owens | Third | 8 out |
| Wednesday, August 2 |
| » Defeated Dodgers (62-39), 6-0 | Los Angeles Memorial Coliseum (4-2) | 55-46 | Won 3 |
| » Starters: Juan Marichal vs Johnny Podres | Third | 8 out |
| Thursday, August 3 |
| » Lost to Dodgers (63-39), 4-3 | Los Angeles Memorial Coliseum (4-3) | 55-47 | |
| » Starters: Jack Sanford vs Stan Williams | Third | 9 out |
| Friday, August 4 |
| » Lost to Braves (53-48), 2-1 | Candlestick Park (25-26) | 55-48 | Lost 2 |
| » Starters: Warren Spahn vs Mike McCormick | Third | 10 out |
| Saturday, August 5 |
| » Lost to Braves (54-48), 9-3 | Candlestick Park (25-27) | 55-49 | Lost 3 |
| » Starters: Bob Buhl vs Sam Jones | Third | 10 out |
| Sunday, August 6 |
| » Defeated Braves (54-49), 4-3 | Candlestick Park (26-27) | 56-49 | |
| » Starters: Carl Willey vs Juan Marichal | Third | 9 out |
| Tuesday, August 8 |
| » Defeated Cubs (44-61), 8-1 | Candlestick Park (27-27) | 57-49 | Won 2 |
| » Starters: Don Cardwell vs Jack Sanford | Third | 9 out |
| Wednesday, August 9 |
| » Defeated Cubs (44-62), 6-5 | Candlestick Park (28-27) | 58-49 | Won 3 |
| » Starters: Bob Anderson vs Mike McCormick | Third | 9 out |
| Friday, August 11 |
| » Defeated Reds (69-45), 4-2 | Candlestick Park (29-27) | 59-49 | Won 4 |
| » Starters: Jim O'Toole vs Juan Marichal | Third | 8½ out |
| Saturday, August 12 |
| » Defeated Reds (69-46), 6-4 | Candlestick Park (30-27) | 60-49 | Won 5 |
| » Starters: Bob Purkey vs Jack Sanford | Third | 8½ out |
| Sunday, August 13 |
| » Lost to Reds (70-46), 8-1 | Candlestick Park (30-28) | 60-50 | |
| » Starters: Ken Johnson vs Mike McCormick | Third | 9½ out |
| Tuesday, August 15 |
| » Defeated Cardinals (57-56), 3-2 | Candlestick Park (31-28) | 61-50 | |
| » Starters: Curt Simmons vs Juan Marichal | Third | 8 out |
| Future Giant Chris Brown is born in Jackson, MS. |
| Wednesday, August 16 |
| » Defeated Cardinals (57-57), 4-3 | Candlestick Park (32-28) | 62-50 | Won 2 |
| » Starters: Ray Sadecki vs Jack Sanford | Third | 7½ out |
| Thursday, August 17 |
| » Lost to Cardinals (58-57), 2-0 | Candlestick Park (32-29) | 62-51 | |
| » Starters: Larry Jackson vs Mike McCormick | Third | 8 out |
| Friday, August 18 |
| » Defeated Dodgers (69-45), 2-1 | Candlestick Park (33-29) | 63-51 | |
| » Starters: Don Drysdale vs Billy Loes | Third | 8 out |
| Saturday, August 19 |
| » Defeated Dodgers (69-46), 5-0 | Candlestick Park (34-29) | 64-51 | Won 2 |
| » Starters: Stan Williams vs Juan Marichal | Third | 8 out |
| Sunday, August 20 |
| » Defeated Dodgers (69-47), 11-8 | Candlestick Park (35-29) | 65-51 | Won 3 |
| » Starters: Sandy Koufax vs Jack Sanford | Third | 7 out |
| Tuesday, August 22 |
| » Defeated Reds (75-48), 12-2 | Crosley Field (3-2) | 66-51 | Won 4 |
| » Starters: Mike McCormick vs Bob Purkey | Third | 5 out |
| » Defeated Reds (75-49), 5-3 | Crosley Field (4-2) | 67-51 | Won 5 |
| » Starters: Sam Jones vs Ken Johnson | Third | 5 out |
| Wednesday, August 23 |
| » Defeated Reds (75-50), 14-0 | Crosley Field (5-2) | 68-51 | Won 6 |
| » Starters: Juan Marichal vs Joey Jay | Third | 4 out |
| Thursday, August 24 |
| » Lost to Reds (76-50), 8-5 | Crosley Field (5-3) | 68-52 | |
| » Starters: Jack Sanford vs Jim O'Toole | Third | 5 out |
| Friday, August 25 |
| » Lost to Cardinals (63-59), 7-3 | Sportsman's Park III (4-5) | 68-53 | Lost 2 |
| » Starters: Billy O'Dell vs Ray Sadecki | Third | 5 out |
| Saturday, August 26 |
| » Lost to Cardinals (64-59), 8-5 | Sportsman's Park III (4-6) | 68-54 | Lost 3 |
| » Starters: Mike McCormick vs Bob Gibson | Third | 5 out |
| Sunday, August 27 |
| » Lost to Cardinals (65-59), 6-0 | Sportsman's Park III (4-7) | 68-55 | Lost 4 |
| » Starters: Juan Marichal vs Larry Jackson | Third | 6½ out |
| Tuesday, August 29 |
| » Lost to Braves (69-56), 7-6 | County Stadium (2-5) | 68-56 | Lost 5 |
| » Starters: Jack Sanford vs Lew Burdette | Fourth | 7½ out |
| Wednesday, August 30 |
| » Defeated Braves (69-57), 2-1 | County Stadium (3-5) | 69-56 | |
| » Starters: Mike McCormick vs Carl Willey | Third | 6½ out |
| Thursday, August 31 |
| » Lost to Cubs (54-73), 6-1 | Wrigley Field (6-3) | 69-57 | |
| » Starters: Juan Marichal vs Jack Curtis | Fourth | 7 out |
| Friday, September 1 |
| » Defeated Cubs (54-74), 4-3 | Wrigley Field (7-3) | 70-57 | |
| » Starters: Dick LeMay vs Glen Hobbie | Third | 6½ out |
| Saturday, September 2 |
| » Lost to Cubs (55-74), 7-0 | Wrigley Field (7-4) | 70-58 | |
| » Starters: Jack Sanford vs Don Cardwell | Fourth | 7½ out |
| Sunday, September 3 |
| » Lost to Dodgers (75-54), 5-4 | Los Angeles Memorial Coliseum (4-4) | 70-59 | Lost 2 |
| » Starters: Mike McCormick vs Johnny Podres | Fourth | 7½ out |
| Monday, September 4 |
| » Lost to Dodgers (76-54), 4-0 | Los Angeles Memorial Coliseum (4-5) | 70-60 | Lost 3 |
| » Starters: Juan Marichal vs Don Drysdale | Fourth | 8 out |
| Tuesday, September 5 |
| » Lost to Dodgers (77-54), 4-2 | Los Angeles Memorial Coliseum (4-6) | 70-61 | Lost 4 |
| » Starters: Sam Jones vs Stan Williams | Fourth | 9 out |
| Wednesday, September 6 |
| » Lost to Dodgers (78-54), 9-5 | Los Angeles Memorial Coliseum (4-7) | 70-62 | Lost 5 |
| » Starters: Jack Sanford vs Sandy Koufax | Fourth | 9 out |
| Friday, September 8 |
| » Defeated Dodgers (78-55), 7-3 | Candlestick Park (36-29) | 71-62 | |
| » Starters: Johnny Podres vs Mike McCormick | Fourth | 9 out |
| Saturday, September 9 |
| » Defeated Dodgers (78-56), 9-6 | Candlestick Park (37-29) | 72-62 | Won 2 |
| » Starters: Don Drysdale vs Juan Marichal | Fourth | 9 out |
| Former Giant Jesse Barnes dies in Santa Rosa, NM at the age of 70. |
| Sunday, September 10 |
| » Defeated Dodgers (78-57), 7-1 | Candlestick Park (38-29) | 73-62 | Won 3 |
| » Starters: Stan Williams vs Billy Loes | Fourth | 9 out |
| Monday, September 11 |
| » Defeated Pirates (66-70), 4-3 | Candlestick Park (39-29) | 74-62 | Won 4 |
| » Starters: Al McBean vs Jack Sanford | Fourth | 8½ out |
| Tuesday, September 12 |
| » Lost to Pirates (67-70), 3-0 | Candlestick Park (39-30) | 74-63 | |
| » Starters: Joe Gibbon vs Mike McCormick | Fourth | 9½ out |
| Wednesday, September 13 |
| » Defeated Phillies (42-99), 8-2 | Candlestick Park (40-30) | 75-63 | |
| » Starters: Dallas Green vs Jim Duffalo | Fourth | 9½ out |
| Thursday, September 14 |
| » Lost to Phillies (43-99), 4-3 | Candlestick Park (40-31) | 75-64 | |
| » Starters: John Buzhardt vs Billy Loes | Fourth | 10 out |
| Friday, September 15 |
| » Defeated Cubs (59-83), 5-1 | Candlestick Park (41-31) | 76-64 | |
| » Starters: Dick Drott vs Jack Sanford | Third | 9½ out |
| Saturday, September 16 |
| » Defeated Cubs (59-84), 4-3 | Candlestick Park (42-31) | 77-64 | Won 2 |
| » Starters: Dick Ellsworth vs Mike McCormick | Third | 9½ out |
| Sunday, September 17 |
| » Defeated Cubs (59-85), 8-2 | Candlestick Park (43-31) | 78-64 | Won 3 |
| » Starters: Jack Curtis vs Billy O'Dell | Third | 8½ out |
| Monday, September 18 |
| » Defeated Braves (76-68), 3-2 | Candlestick Park (44-31) | 79-64 | Won 4 |
| » Starters: Bob Hendley vs Jim Duffalo | Third | 8 out |
| Tuesday, September 19 |
| » Defeated Braves (76-69), 11-10 | Candlestick Park (45-31) | 80-64 | Won 5 |
| » Starters: Warren Spahn vs Jack Sanford | Third | 8 out |
| Wednesday, September 20 |
| » Lost to Braves (77-69), 7-4 | Candlestick Park (45-32) | 80-65 | |
| » Starters: Lew Burdette vs Mike McCormick | Third | 9 out |
| Friday, September 22 |
| » Defeated Reds (90-58), 6-0 | Crosley Field (6-3) | 81-65 | |
| » Starters: Billy O'Dell vs Bob Purkey | Third | 8 out |
| Saturday, September 23 |
| » Lost to Reds (91-58), 10-6 | Crosley Field (6-4) | 81-66 | |
| » Starters: Jim Duffalo vs Jim O'Toole | Third | 9 out |
| Sunday, September 24 |
| » Defeated Reds (91-59), 12-5 | Crosley Field (7-4) | 82-66 | |
| » Starters: Jack Sanford vs Joey Jay | Third | 8 out |
| Monday, September 25 |
| » Defeated Phillies (46-104), 10-2 | Shibe Park (9-2) | 83-66 | Won 2 |
| » Starters: Mike McCormick vs Don Ferrarese | Third | 7½ out |
| Wednesday, September 27 |
| » Lost to Pirates (73-77), 5-3 | Forbes Field (4-6) | 83-67 | |
| » Starters: Billy O'Dell vs Tom Sturdivant | Third | 8½ out |
| Thursday, September 28 |
| » Defeated Pirates (73-78), 7-4 | Forbes Field (5-6) | 84-67 | |
| » Starters: Jim Duffalo vs Earl Francis | Third | 8 out |
| Future Giant Ed Vosberg is born in Tucson, AZ. |
| Friday, September 29 |
| » Lost to Braves (82-70), 4-1 | County Stadium (3-6) | 84-68 | |
| » Starters: Jack Sanford vs Warren Spahn | Third | 9 out |
| Sunday, October 1 |
| » Defeated Braves (82-71), 8-2 | County Stadium (4-6) | 85-68 | |
| » Starters: Billy O'Dell vs Lew Burdette | Third | 8 out |
| » Lost to Braves (83-71), 3-2 | County Stadium (4-7) | 85-69 | |
| » Starters: Mike McCormick vs Ron Piche | Third | 8 out |
| Tuesday, October 17 |
| Former Giant Harry Felix dies in Miami, FL at the age of 83. |
| Friday, October 27 |
| Future Giant Bill Swift is born in Portland, ME. |
| Saturday, October 28 |
| Future Giant Bob Melvin is born in Palo Alto, CA. |
| Monday, October 30 |
| Future Giant Scott Garrelts is born in Urbana, IL. |
| Friday, November 3 |
| Former Giant Freddie Maguire dies in Boston, MA at the age of 63. |
| Saturday, November 4 |
| Future Giant Mark Bailey is born in Springfield, MO. |
| Saturday, November 18 |
| Future Giant Mike Felder is born in Vallejo, CA. |
| Friday, December 22 |
| Future Giant Andy Allanson is born in Richmond, VA. |
| Sunday, December 31 |
| Future Giant Donell Nixon is born in Evergreen, NC. |
Game information provided by Retrosheet (www.retrosheet.org) |
