| Friday, January 8 |
| Future Athletic Randy Ready is born in Fremont, CA. |
| Thursday, January 21 |
| Future Athletic Andy Hawkins is born in Waco, TX. |
| Monday, March 14 |
| Future Athletic Jerry Willard is born in Oxnard, CA. |
| Tuesday, March 22 |
| Future Athletic Matt Sinatro is born in Hartford, CT. |
| Saturday, April 16 |
| Future Athletic Curt Young is born in Saginaw, MI. |
| Sunday, April 17 |
| » Major-league debuts: Chris Cannizzaro (Cardinals) |
| Monday, April 18 |
| » Major-league debuts: Don Mincher (Senators) |
| Tuesday, April 19 |
| » Lost to White Sox (1-0), 10-9 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Bud Daley vs Early Wynn | Third | 1 out |
| Thursday, April 21 |
| » Lost to White Sox (2-0), 6-5 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Ned Garver vs Bob Shaw | Sixth | 2 out |
| Friday, April 22 |
| » Defeated Indians (0-3), 4-1 | Municipal Stadium (1-0) | 1-2 | |
| » Starters: Wynn Hawkins vs Ray Herbert | Sixth | 2 out |
| » Major-league debuts: Wynn Hawkins and Dick Stigman (Indians) |
| Saturday, April 23 |
| » Defeated Indians (0-4), 6-5 | Municipal Stadium (2-0) | 2-2 | Won 2 |
| » Starters: Barry Latman vs Dick Hall | Third | 2 out |
| Sunday, April 24 |
| » Lost to Indians (1-4), 7-0 | Municipal Stadium (2-1) | 2-3 | |
| » Starters: Gary Bell vs Don Larsen | Fifth | 3 out |
| Monday, April 25 |
| » Defeated White Sox (2-4), 6-1 | Municipal Stadium (3-1) | 3-3 | |
| » Starters: Herb Score vs Bud Daley | Third | 2½ out |
| Tuesday, April 26 |
| » Lost to White Sox (3-4), 8-0 | Municipal Stadium (3-2) | 3-4 | |
| » Starters: Bob Shaw vs Ned Garver | Fifth | 2½ out |
| Wednesday, April 27 |
| » Defeated Tigers (5-2), 3-1 | Municipal Stadium (4-2) | 4-4 | |
| » Starters: Hank Aguirre vs Ray Herbert | Third | 1½ out |
| Thursday, April 28 |
| » Defeated Tigers (5-3), 2-1 | Municipal Stadium (5-2) | 5-4 | Won 2 |
| » Starters: Don Mossi vs Dick Hall | Second | ½ out |
| Friday, April 29 |
| » Lost to Indians (3-5), 5-4 | Cleveland Stadium (0-1) | 5-5 | |
| » Starters: Don Larsen vs Jim Perry | Third | ½ out |
| Saturday, April 30 |
| » Lost to Indians (4-5), 2-1 | Cleveland Stadium (0-2) | 5-6 | Lost 2 |
| » Starters: Bud Daley vs Barry Latman | Fourth | 1½ out |
| Sunday, May 1 |
| » Lost to Indians (5-5), 6-4 | Cleveland Stadium (0-3) | 5-7 | Lost 3 |
| » Starters: Ned Garver vs Wynn Hawkins | Fifth | 3 out |
| » Lost to Indians (6-5), 3-1 | Cleveland Stadium (0-4) | 5-8 | Lost 4 |
| » Starters: George Brunet vs Dick Stigman | Fifth | 3 out |
| Future Athletic Charlie O'Brien is born in Tulsa, OK. |
| Tuesday, May 3 |
| » Lost to Red Sox (6-6), 4-3 | Fenway Park (0-1) | 5-9 | Lost 5 |
| » Starters: Ray Herbert vs Jerry Casale | Eighth | 3½ out |
| Wednesday, May 4 |
| » Defeated Red Sox (6-7), 5-3 | Fenway Park (1-1) | 6-9 | |
| » Starters: Dick Hall vs Tom Brewer | Sixth | 3 out |
| Friday, May 6 |
| » Lost to Yankees (9-5), 8-7 | Yankee Stadium (0-1) | 6-10 | |
| » Starters: Bud Daley vs Jim Coates | Seventh | 4 out |
| Former Athletic Merlin Kopp dies in Sacramento, CA at the age of 69. |
| Saturday, May 7 |
| » Lost to Yankees (10-5), 4-1 | Yankee Stadium (0-2) | 6-11 | Lost 2 |
| » Starters: George Brunet vs Ralph Terry | Seventh | 5 out |
| Monday, May 9 |
| » Lost to Senators (8-10), 8-1 | Griffith Stadium (0-1) | 6-12 | Lost 3 |
| » Starters: Ray Herbert vs Camilo Pascual | Eighth | 6 out |
| Tuesday, May 10 |
| » Defeated Orioles (10-10), 10-0 | Memorial Stadium (1-0) | 7-12 | |
| » Starters: Dick Hall vs Hoyt Wilhelm | Eighth | 5 out |
| Wednesday, May 11 |
| » Lost to Orioles (11-10), 5-3 | Memorial Stadium (1-1) | 7-13 | |
| » Starters: Bud Daley vs Arnie Portocarrero | Eighth | 5½ out |
| Friday, May 13 |
| » Lost to Tigers (8-10), 4-3 | Tiger Stadium (0-1) | 7-14 | Lost 2 |
| » Starters: Ray Herbert vs Jim Bunning | Eighth | 6 out |
| Saturday, May 14 |
| » Lost to Tigers (9-10), 7-6 | Tiger Stadium (0-2) | 7-15 | Lost 3 |
| » Starters: Johnny Kucks vs Paul Foytack | Eighth | 6 out |
| Sunday, May 15 |
| » Defeated Tigers (9-11), 5-0 | Tiger Stadium (1-2) | 8-15 | |
| » Starters: Bud Daley vs Don Mossi | Seventh | 5 out |
| » Defeated Tigers (9-12), 5-4 | Tiger Stadium (2-2) | 9-15 | Won 2 |
| » Starters: Dick Hall vs Pete Burnside | Seventh | 5 out |
| Monday, May 16 |
| » Lost to Orioles (15-10), 2-1 | Municipal Stadium (5-3) | 9-16 | |
| » Starters: Arnie Portocarrero vs Ned Garver | Eighth | 6 out |
| Tuesday, May 17 |
| » Defeated Orioles (15-11), 4-2 | Municipal Stadium (6-3) | 10-16 | |
| » Starters: Milt Pappas vs Don Larsen | Seventh | 5½ out |
| Wednesday, May 18 |
| » Lost to Orioles (16-11), 5-4 | Municipal Stadium (6-4) | 10-17 | |
| » Starters: Hoyt Wilhelm vs Ray Herbert | Eighth | 6½ out |
| Thursday, May 19 |
| » Defeated Orioles (16-12), 7-4 | Municipal Stadium (7-4) | 11-17 | |
| » Starters: Chuck Estrada vs Bud Daley | Eighth | 6 out |
| Saturday, May 21 |
| » Defeated Senators (10-16), 5-2 | Municipal Stadium (8-4) | 12-17 | Won 2 |
| » Starters: Jim Kaat vs Dick Hall | Seventh | 6½ out |
| Sunday, May 22 |
| » Lost to Yankees (14-12), 9-7 | Municipal Stadium (8-5) | 12-18 | |
| » Starters: Jim Coates vs Ned Garver | Seventh | 6 out |
| Monday, May 23 |
| » Lost to Yankees (15-12), 4-3 | Municipal Stadium (8-6) | 12-19 | Lost 2 |
| » Starters: Bob Turley vs Ray Herbert | Seventh | 6½ out |
| Tuesday, May 24 |
| » Defeated Red Sox (10-17), 6-2 | Municipal Stadium (9-6) | 13-19 | |
| » Starters: Dave Hillman vs Bud Daley | Seventh | 6 out |
| Wednesday, May 25 |
| » Lost to Red Sox (11-17), 5-3 | Municipal Stadium (9-7) | 13-20 | |
| » Starters: Bill Monbouquette vs Don Larsen | Sixth | 7 out |
| Thursday, May 26 |
| » Lost to White Sox (19-14), 3-1 | Municipal Stadium (9-8) | 13-21 | Lost 2 |
| » Starters: Bob Shaw vs Dick Hall | Seventh | 7 out |
| Friday, May 27 |
| » Lost to White Sox (20-14), 7-4 | Municipal Stadium (9-9) | 13-22 | Lost 3 |
| » Starters: Billy Pierce vs Ray Herbert | Eighth | 8 out |
| Saturday, May 28 |
| » Defeated White Sox (20-15), 4-3 | Municipal Stadium (10-9) | 14-22 | |
| » Starters: Dick Donovan vs Bud Daley | Eighth | 7½ out |
| Sunday, May 29 |
| » Defeated White Sox (20-16), 4-2 | Municipal Stadium (11-9) | 15-22 | Won 2 |
| » Starters: Herb Score vs Ken Johnson | Sixth | 8 out |
| Monday, May 30 |
| » Defeated Tigers (17-16), 7-6 | Municipal Stadium (12-9) | 16-22 | Won 3 |
| » Starters: Hank Aguirre vs Johnny Kucks | Sixth | 7 out |
| » Defeated Tigers (17-17), 8-2 | Municipal Stadium (13-9) | 17-22 | Won 4 |
| » Starters: Paul Foytack vs Don Larsen | Sixth | 7 out |
| Tuesday, May 31 |
| » Defeated Tigers (17-18), 2-1 | Municipal Stadium (14-9) | 18-22 | Won 5 |
| » Starters: Pete Burnside vs Dick Hall | Sixth | 7 out |
| Future Athletic Jeff Schaefer is born in Patchogue, NY. |
| Thursday, June 2 |
| » Lost to Indians (22-15), 7-6 | Municipal Stadium (14-10) | 18-23 | |
| » Starters: Mudcat Grant vs Ray Herbert | Sixth | 8½ out |
| Friday, June 3 |
| » Defeated White Sox (22-20), 7-2 | Comiskey Park I (1-2) | 19-23 | |
| » Starters: Bud Daley vs Early Wynn | Sixth | 7½ out |
| Saturday, June 4 |
| » Lost to White Sox (23-20), 4-2 | Comiskey Park I (1-3) | 19-24 | |
| » Starters: Ken Johnson vs Bob Shaw | Sixth | 7½ out |
| Sunday, June 5 |
| » Lost to White Sox (24-20), 2-0 | Comiskey Park I (1-4) | 19-25 | Lost 2 |
| » Starters: Dick Hall vs Russ Kemmerer | Seventh | 9 out |
| » Lost to White Sox (25-20), 2-0 | Comiskey Park I (1-5) | 19-26 | Lost 3 |
| » Starters: Ned Garver vs Frank Baumann | Seventh | 9 out |
| Tuesday, June 7 |
| » Lost to Senators (19-25), 7-2 | Griffith Stadium (0-2) | 19-27 | Lost 4 |
| » Starters: Ray Herbert vs Camilo Pascual | Seventh | 9½ out |
| Wednesday, June 8 |
| » Lost to Senators (20-25), 8-6 | Griffith Stadium (0-3) | 19-28 | Lost 5 |
| » Starters: Bud Daley vs Hal Woodeshick | Seventh | 9½ out |
| Thursday, June 9 |
| » Defeated Senators (20-26), 7-2 | Griffith Stadium (1-3) | 20-28 | |
| » Starters: Ken Johnson vs Pedro Ramos | Seventh | 9½ out |
| Friday, June 10 |
| » Lost to Orioles (30-21), 5-4 | Memorial Stadium (1-2) | 20-29 | |
| » Starters: Dick Hall vs Steve Barber | Seventh | 9½ out |
| Saturday, June 11 |
| » Lost to Orioles (31-21), 6-5 | Memorial Stadium (1-3) | 20-30 | Lost 2 |
| » Starters: Ray Herbert vs Jerry Walker | Seventh | 10 out |
| Sunday, June 12 |
| » Defeated Orioles (31-22), 6-1 | Memorial Stadium (2-3) | 21-30 | |
| » Starters: Bud Daley vs Chuck Estrada | Seventh | 8½ out |
| » Defeated Orioles (31-23), 5-3 | Memorial Stadium (3-3) | 22-30 | Won 2 |
| » Starters: Bob Trowbridge vs Hoyt Wilhelm | Seventh | 8½ out |
| Monday, June 13 |
| » Lost to Yankees (28-21), 8-4 | Municipal Stadium (14-11) | 22-31 | |
| » Starters: Bob Turley vs Ken Johnson | Seventh | 9 out |
| Tuesday, June 14 |
| » Lost to Yankees (29-21), 6-2 | Municipal Stadium (14-12) | 22-32 | Lost 2 |
| » Starters: Jim Coates vs Johnny Kucks | Seventh | 9 out |
| Wednesday, June 15 |
| » Tied Yankees, 7-7 | Municipal Stadium (14-12) | 22-32 | |
| » Starters: Ralph Terry vs Dick Hall | Sixth | 9 out |
| Thursday, June 16 |
| » Defeated Yankees (29-22), 9-1 | Municipal Stadium (15-12) | 23-32 | |
| » Starters: Whitey Ford vs Bud Daley | Sixth | 9½ out |
| Friday, June 17 |
| » Lost to Senators (23-30), 3-1 | Municipal Stadium (15-13) | 23-33 | |
| » Starters: Camilo Pascual vs Ray Herbert | Seventh | 10½ out |
| Saturday, June 18 |
| » Lost to Senators (24-30), 7-2 | Municipal Stadium (15-14) | 23-34 | Lost 2 |
| » Starters: Hal Woodeshick vs Ken Johnson | Seventh | 10 out |
| Sunday, June 19 |
| » Lost to Senators (25-30), 6-5 | Municipal Stadium (15-15) | 23-35 | Lost 3 |
| » Starters: Don Lee vs Johnny Kucks | Seventh | 11½ out |
| Monday, June 20 |
| » Defeated Red Sox (21-36), 9-6 | Municipal Stadium (16-15) | 24-35 | |
| » Starters: Tom Borland vs Dick Hall | Seventh | 11 out |
| Tuesday, June 21 |
| » Defeated Red Sox (21-37), 11-7 | Municipal Stadium (17-15) | 25-35 | Won 2 |
| » Starters: Jerry Casale vs Bud Daley | Seventh | 11 out |
| Wednesday, June 22 |
| » Defeated Red Sox (21-38), 2-1 | Municipal Stadium (18-15) | 26-35 | Won 3 |
| » Starters: Frank Sullivan vs Ray Herbert | Seventh | 11 out |
| Thursday, June 23 |
| » Lost to Red Sox (22-38), 13-4 | Municipal Stadium (18-16) | 26-36 | |
| » Starters: Ike Delock vs Ken Johnson | Seventh | 11 out |
| Friday, June 24 |
| » Lost to Orioles (39-27), 6-5 | Municipal Stadium (18-17) | 26-37 | Lost 2 |
| » Starters: Hal Brown vs Don Larsen | Seventh | 12 out |
| Saturday, June 25 |
| » Lost to Orioles (40-27), 11-2 | Municipal Stadium (18-18) | 26-38 | Lost 3 |
| » Starters: Milt Pappas vs Bud Daley | Seventh | 12 out |
| Sunday, June 26 |
| » Lost to Orioles (41-27), 9-2 | Municipal Stadium (18-19) | 26-39 | Lost 4 |
| » Starters: Chuck Estrada vs Dick Hall | Seventh | 13½ out |
| Tuesday, June 28 |
| » Lost to Yankees (38-25), 5-2 | Yankee Stadium (0-3) | 26-40 | Lost 5 |
| » Starters: Bud Daley vs Bob Turley | Seventh | 13½ out |
| Wednesday, June 29 |
| » Lost to Yankees (39-25), 10-0 | Yankee Stadium (0-4) | 26-41 | Lost 6 |
| » Starters: Ray Herbert vs Jim Coates | Seventh | 14½ out |
| Thursday, June 30 |
| » Lost to Yankees (40-25), 10-3 | Yankee Stadium (0-5) | 26-42 | Lost 7 |
| » Starters: Don Larsen vs Ralph Terry | Seventh | 15½ out |
| Saturday, July 2 |
| » Defeated Red Sox (24-44), 10-6 | Fenway Park (2-1) | 27-42 | |
| » Starters: Bud Daley vs Frank Sullivan | Seventh | 15½ out |
| Sunday, July 3 |
| » Lost to Red Sox (25-44), 13-2 | Fenway Park (2-2) | 27-43 | |
| » Starters: Dick Hall vs Ike Delock | Seventh | 17 out |
| Monday, July 4 |
| » Lost to Indians (41-28), 4-0 | Cleveland Stadium (0-5) | 27-44 | Lost 2 |
| » Starters: Ray Herbert vs Gary Bell | Seventh | 17½ out |
| » Lost to Indians (42-28), 7-4 | Cleveland Stadium (0-6) | 27-45 | Lost 3 |
| » Starters: Johnny Kucks vs Ted Bowsfield | Seventh | 17½ out |
| Wednesday, July 6 |
| » Defeated Tigers (34-38), 6-4 | Tiger Stadium (3-2) | 28-45 | |
| » Starters: Bud Daley vs Frank Lary | Seventh | 17 out |
| Thursday, July 7 |
| » Lost to Tigers (35-38), 6-3 | Tiger Stadium (3-3) | 28-46 | |
| » Starters: Don Larsen vs Don Mossi | Seventh | 18 out |
| Friday, July 8 |
| » Defeated Tigers (35-39), 5-4 | Municipal Stadium (19-19) | 29-46 | |
| » Starters: Jim Bunning vs Ray Herbert | Sixth | 17 out |
| Saturday, July 9 |
| » Lost to Tigers (36-39), 6-1 | Municipal Stadium (19-20) | 29-47 | |
| » Starters: Pete Burnside vs Dick Hall | Sixth | 17 out |
| Sunday, July 10 |
| » Lost to Tigers (37-39), 12-10 | Municipal Stadium (19-21) | 29-48 | Lost 2 |
| » Starters: Frank Lary vs Bud Daley | Seventh | 17 out |
| Friday, July 15 |
| » Lost to Red Sox (31-48), 2-1 | Municipal Stadium (19-22) | 29-49 | Lost 3 |
| » Starters: Bill Monbouquette vs Bud Daley | Eighth | 17 out |
| Saturday, July 16 |
| » Lost to Red Sox (32-48), 1-0 | Municipal Stadium (19-23) | 29-50 | Lost 4 |
| » Starters: Ike Delock vs Ray Herbert | Eighth | 18 out |
| Sunday, July 17 |
| » Lost to Red Sox (33-48), 4-2 | Municipal Stadium (19-24) | 29-51 | Lost 5 |
| » Starters: Tom Brewer vs Dick Hall | Eighth | 17½ out |
| Monday, July 18 |
| » Defeated Orioles (47-41), 5-1 | Municipal Stadium (20-24) | 30-51 | |
| » Starters: Hal Brown vs Ned Garver | Eighth | 17½ out |
| Tuesday, July 19 |
| » Lost to Orioles (48-41), 9-3 | Municipal Stadium (20-25) | 30-52 | |
| » Starters: Chuck Estrada vs Bud Daley | Seventh | 18½ out |
| Wednesday, July 20 |
| » Defeated Orioles (48-42), 4-3 | Municipal Stadium (21-25) | 31-52 | |
| » Starters: Milt Pappas vs Ray Herbert | Eighth | 17½ out |
| Friday, July 22 |
| » Defeated Senators (41-43), 9-4 | Griffith Stadium (2-3) | 32-52 | Won 2 |
| » Starters: Dick Hall vs Hal Woodeshick | Seventh | 16½ out |
| Saturday, July 23 |
| » Lost to Senators (42-43), 8-3 | Griffith Stadium (2-4) | 32-53 | |
| » Starters: Bud Daley vs Pedro Ramos | Eighth | 17½ out |
| Sunday, July 24 |
| » Defeated Senators (42-44), 6-3 | Griffith Stadium (3-4) | 33-53 | |
| » Starters: Ray Herbert vs Tex Clevenger | Eighth | 17½ out |
| » Lost to Senators (43-44), 10-2 | Griffith Stadium (3-5) | 33-54 | |
| » Starters: Ned Garver vs Camilo Pascual | Eighth | 17½ out |
| Future Athletic Jeff Kaiser is born in Wyandotte, MI. |
| Tuesday, July 26 |
| » Defeated Orioles (51-44), 2-1 | Memorial Stadium (4-3) | 34-54 | |
| » Starters: Johnny Kucks vs Milt Pappas | Seventh | 17½ out |
| Thursday, July 28 |
| » Lost to Orioles (52-44), 5-0 | Memorial Stadium (4-4) | 34-55 | |
| » Starters: Bud Daley vs Steve Barber | Eighth | 18 out |
| Friday, July 29 |
| » Defeated Yankees (52-38), 5-2 | Yankee Stadium (1-5) | 35-55 | |
| » Starters: Ray Herbert vs Eli Grba | Eighth | 17 out |
| Sunday, July 31 |
| » Defeated Yankees (52-39), 5-2 | Yankee Stadium (2-5) | 36-55 | Won 2 |
| » Starters: Johnny Kucks vs Bill Short | Eighth | 18½ out |
| » Lost to Yankees (53-39), 6-0 | Yankee Stadium (2-6) | 36-56 | |
| » Starters: Bud Daley vs Art Ditmar | Eighth | 18½ out |
| Monday, August 1 |
| » Defeated Red Sox (39-56), 10-8 | Fenway Park (3-2) | 37-56 | |
| » Starters: Dick Hall vs Ike Delock | Eighth | 17½ out |
| Tuesday, August 2 |
| » Defeated Red Sox (39-57), 10-4 | Fenway Park (4-2) | 38-56 | Won 2 |
| » Starters: Ray Herbert vs Tom Brewer | Eighth | 17½ out |
| Thursday, August 4 |
| » Lost to Red Sox (40-57), 5-3 | Fenway Park (4-3) | 38-57 | |
| » Starters: John Briggs vs Bill Monbouquette | Eighth | 18 out |
| » Lost to Red Sox (41-57), 9-1 | Fenway Park (4-4) | 38-58 | Lost 2 |
| » Starters: Don Larsen vs Earl Wilson | Eighth | 18 out |
| Friday, August 5 |
| » Lost to Yankees (57-40), 4-3 | Municipal Stadium (21-26) | 38-59 | Lost 3 |
| » Starters: Art Ditmar vs Johnny Kucks | Eighth | 19 out |
| Saturday, August 6 |
| » Lost to Yankees (58-40), 16-4 | Municipal Stadium (21-27) | 38-60 | Lost 4 |
| » Starters: Bill Short vs Dick Hall | Eighth | 20 out |
| Sunday, August 7 |
| » Lost to Yankees (59-40), 3-2 | Municipal Stadium (21-28) | 38-61 | Lost 5 |
| » Starters: Eli Grba vs Ray Herbert | Eighth | 20 out |
| » Defeated Yankees (59-41), 13-3 | Municipal Stadium (22-28) | 39-61 | |
| » Starters: Ralph Terry vs Bud Daley | Eighth | 20 out |
| Monday, August 8 |
| » Lost to Senators (50-53), 10-7 | Municipal Stadium (22-29) | 39-62 | |
| » Starters: Hal Woodeshick vs John Tsitouris | Eighth | 20 out |
| Tuesday, August 9 |
| » Lost to Senators (51-53), 3-1 | Municipal Stadium (22-30) | 39-63 | Lost 2 |
| » Starters: Don Lee vs Johnny Kucks | Seventh | 20½ out |
| » Defeated Senators (51-54), 8-3 | Municipal Stadium (23-30) | 40-63 | |
| » Starters: Jack Kralick vs Don Larsen | Seventh | 20½ out |
| Wednesday, August 10 |
| » Defeated Senators (51-55), 13-1 | Municipal Stadium (24-30) | 41-63 | Won 2 |
| » Starters: Camilo Pascual vs Dick Hall | Eighth | 20½ out |
| Thursday, August 11 |
| » Lost to Senators (52-55), 5-4 | Municipal Stadium (24-31) | 41-64 | |
| » Starters: Tex Clevenger vs Ray Herbert | Eighth | 21 out |
| Friday, August 12 |
| » Lost to White Sox (62-47), 6-4 | Comiskey Park I (1-6) | 41-65 | Lost 2 |
| » Starters: Bud Daley vs Bob Shaw | Eighth | 21 out |
| Saturday, August 13 |
| » Lost to White Sox (63-47), 8-3 | Comiskey Park I (1-7) | 41-66 | Lost 3 |
| » Starters: John Tsitouris vs Frank Baumann | Eighth | 22 out |
| Sunday, August 14 |
| » Lost to White Sox (64-47), 9-3 | Comiskey Park I (1-8) | 41-67 | Lost 4 |
| » Starters: Johnny Kucks vs Billy Pierce | Seventh | 22½ out |
| » Lost to White Sox (65-47), 7-2 | Comiskey Park I (1-9) | 41-68 | Lost 5 |
| » Starters: Don Larsen vs Early Wynn | Seventh | 22½ out |
| Tuesday, August 16 |
| » Lost to Indians (54-54), 4-3 | Cleveland Stadium (0-7) | 41-69 | Lost 6 |
| » Starters: Dick Hall vs Jack Harshman | Eighth | 23½ out |
| Wednesday, August 17 |
| » Lost to Tigers (51-60), 5-2 | Tiger Stadium (3-4) | 41-70 | Lost 7 |
| » Starters: Ray Herbert vs Frank Lary | Eighth | 24½ out |
| Thursday, August 18 |
| » Lost to Tigers (52-60), 11-6 | Tiger Stadium (3-5) | 41-71 | Lost 8 |
| » Starters: Bud Daley vs Pete Burnside | Seventh | 25½ out |
| Friday, August 19 |
| » Lost to White Sox (67-50), 10-0 | Municipal Stadium (24-32) | 41-72 | Lost 9 |
| » Starters: Early Wynn vs Johnny Kucks | Eighth | 25½ out |
| Future Athletic Ron Darling is born in Honolulu, HI. |
| Saturday, August 20 |
| » Lost to White Sox (68-50), 3-0 | Municipal Stadium (24-33) | 41-73 | Lost 10 |
| » Starters: Herb Score vs Don Larsen | Eighth | 26½ out |
| Sunday, August 21 |
| » Defeated White Sox (68-51), 8-1 | Municipal Stadium (25-33) | 42-73 | |
| » Starters: Bob Shaw vs Ray Herbert | Seventh | 25½ out |
| Tuesday, August 23 |
| » Lost to Senators (60-59), 3-1 | Griffith Stadium (3-6) | 42-74 | |
| » Starters: Dick Hall vs Jack Kralick | Eighth | 25½ out |
| Wednesday, August 24 |
| » Defeated Senators (60-60), 6-4 | Griffith Stadium (4-6) | 43-74 | |
| » Starters: Johnny Kucks vs Camilo Pascual | Seventh | 25½ out |
| Thursday, August 25 |
| » Lost to Senators (61-60), 9-0 | Griffith Stadium (4-7) | 43-75 | |
| » Starters: Don Larsen vs Chuck Stobbs | Eighth | 26 out |
| Friday, August 26 |
| » Lost to Orioles (71-52), 2-1 | Memorial Stadium (4-5) | 43-76 | Lost 2 |
| » Starters: Ned Garver vs Steve Barber | Eighth | 28 out |
| » Lost to Orioles (72-52), 11-3 | Memorial Stadium (4-6) | 43-77 | Lost 3 |
| » Starters: Bud Daley vs Hal Brown | Eighth | 28 out |
| Saturday, August 27 |
| » Defeated Orioles (72-53), 5-3 | Memorial Stadium (5-6) | 44-77 | |
| » Starters: Ray Herbert vs Jerry Walker | Eighth | 28½ out |
| Sunday, August 28 |
| » Lost to Red Sox (51-70), 2-1 | Fenway Park (4-5) | 44-78 | |
| » Starters: Dick Hall vs Frank Sullivan | Eighth | 29½ out |
| » Lost to Red Sox (52-70), 5-4 | Fenway Park (4-6) | 44-79 | Lost 2 |
| » Starters: Johnny Kucks vs Billy Muffett | Eighth | 29½ out |
| Monday, August 29 |
| » Lost to Red Sox (53-70), 4-1 | Fenway Park (4-7) | 44-80 | Lost 3 |
| » Starters: Don Larsen vs Tom Brewer | Eighth | 30 out |
| Tuesday, August 30 |
| » Lost to Yankees (74-49), 3-2 | Yankee Stadium (2-7) | 44-81 | Lost 4 |
| » Starters: Bud Daley vs Bob Turley | Eighth | 31 out |
| Wednesday, August 31 |
| » Lost to Yankees (75-49), 1-0 | Yankee Stadium (2-8) | 44-82 | Lost 5 |
| » Starters: Ray Herbert vs Bill Stafford | Eighth | 31 out |
| » Defeated Yankees (75-50), 6-0 | Yankee Stadium (3-8) | 45-82 | |
| » Starters: Ned Garver vs Ralph Terry | Eighth | 31 out |
| Thursday, September 1 |
| » Lost to Indians (61-65), 7-3 | Municipal Stadium (25-34) | 45-83 | |
| » Starters: Barry Latman vs Johnny Kucks | Eighth | 31½ out |
| Friday, September 2 |
| » Lost to Indians (62-65), 6-2 | Municipal Stadium (25-35) | 45-84 | Lost 2 |
| » Starters: Bobby Locke vs Dick Hall | Eighth | 31½ out |
| Saturday, September 3 |
| » Lost to Indians (63-65), 6-5 | Municipal Stadium (25-36) | 45-85 | Lost 3 |
| » Starters: Jim Perry vs Don Larsen | Eighth | 32½ out |
| » Major-league debuts: Frank Funk (Indians) |
| Sunday, September 4 |
| » Lost to Indians (64-65), 10-2 | Municipal Stadium (25-37) | 45-86 | Lost 4 |
| » Starters: Jack Harshman vs Bud Daley | Eighth | 33½ out |
| Monday, September 5 |
| » Defeated White Sox (75-57), 8-7 | Municipal Stadium (26-37) | 46-86 | |
| » Starters: Bob Shaw vs Ray Herbert | Eighth | 33 out |
| Tuesday, September 6 |
| » Defeated White Sox (75-58), 3-2 | Municipal Stadium (27-37) | 47-86 | Won 2 |
| » Starters: Herb Score vs Ned Garver | Eighth | 32½ out |
| Wednesday, September 7 |
| » Lost to Senators (68-66), 5-3 | Municipal Stadium (27-38) | 47-87 | |
| » Starters: Don Lee vs Johnny Kucks | Eighth | 32½ out |
| Thursday, September 8 |
| » Lost to Senators (69-66), 7-0 | Municipal Stadium (27-39) | 47-88 | Lost 2 |
| » Starters: Jack Kralick vs Dick Hall | Eighth | 33½ out |
| Friday, September 9 |
| » Defeated Red Sox (60-76), 3-2 | Municipal Stadium (28-39) | 48-88 | |
| » Starters: Earl Wilson vs Bud Daley | Eighth | 32½ out |
| Saturday, September 10 |
| » Lost to Red Sox (61-76), 7-4 | Municipal Stadium (28-40) | 48-89 | |
| » Starters: Ike Delock vs Ray Herbert | Seventh | 33 out |
| Sunday, September 11 |
| » Lost to Orioles (82-57), 4-0 | Municipal Stadium (28-41) | 48-90 | Lost 2 |
| » Starters: Steve Barber vs Ned Garver | Eighth | 34½ out |
| Former Athletic Charlie High dies in Oak Grove, OR at the age of 62. |
| Tuesday, September 13 |
| » Defeated Yankees (82-56), 12-3 | Municipal Stadium (29-41) | 49-90 | |
| » Starters: Whitey Ford vs Bud Daley | Eighth | 33½ out |
| Wednesday, September 14 |
| » Defeated Yankees (82-57), 2-1 | Municipal Stadium (30-41) | 50-90 | Won 2 |
| » Starters: Art Ditmar vs Ray Herbert | Eighth | 32½ out |
| Friday, September 16 |
| » Lost to Indians (71-70), 4-2 | Cleveland Stadium (0-8) | 50-91 | |
| » Starters: Ned Garver vs Jim Perry | Eighth | 33½ out |
| Future Athletic Mickey Tettleton is born in Oklahoma City, OK. |
| Saturday, September 17 |
| » Defeated Indians (71-71), 8-5 | Cleveland Stadium (1-8) | 51-91 | |
| » Starters: Dick Hall vs Jack Harshman | Eighth | 33½ out |
| Sunday, September 18 |
| » Defeated Indians (71-72), 3-2 | Cleveland Stadium (2-8) | 52-91 | Won 2 |
| » Starters: Ray Herbert vs Bobby Locke | Sixth | 34½ out |
| » Lost to Indians (72-72), 9-2 | Cleveland Stadium (2-9) | 52-92 | |
| » Starters: Johnny Kucks vs Barry Latman | Sixth | 34½ out |
| Tuesday, September 20 |
| » Major-league debuts: Deron Johnson (Yankees) |
| Wednesday, September 21 |
| » Lost to White Sox (84-62), 7-2 | Comiskey Park I (1-10) | 52-93 | Lost 2 |
| » Starters: Bud Daley vs Herb Score | Eighth | 36 out |
| » Major-league debuts: Leo Posada (Athletics) |
| Thursday, September 22 |
| » Major-league debuts: Dick Bertell (Cubs) |
| Friday, September 23 |
| » Defeated Tigers (67-80), 4-1 | Tiger Stadium (4-5) | 53-93 | |
| » Starters: Ned Garver vs Jim Bunning | Eighth | 36 out |
| Saturday, September 24 |
| » Defeated Tigers (67-81), 6-3 | Tiger Stadium (5-5) | 54-93 | Won 2 |
| » Starters: Dick Hall vs Bob Bruce | Eighth | 36 out |
| Sunday, September 25 |
| » Lost to Tigers (68-81), 6-5 | Tiger Stadium (5-6) | 54-94 | |
| » Starters: Johnny Kucks vs Frank Lary | Eighth | 37 out |
| Monday, September 26 |
| » Defeated Indians (74-75), 6-1 | Municipal Stadium (31-41) | 55-94 | |
| » Starters: Dick Stigman vs Bud Daley | Seventh | 37 out |
| Tuesday, September 27 |
| » Defeated Indians (74-76), 5-4 | Municipal Stadium (32-41) | 56-94 | Won 2 |
| » Starters: Barry Latman vs Ray Herbert | Eighth | 37 out |
| Wednesday, September 28 |
| » Defeated Indians (74-77), 4-0 | Municipal Stadium (33-41) | 57-94 | Won 3 |
| » Starters: Jim Perry vs Ned Garver | Eighth | 37 out |
| Friday, September 30 |
| » Lost to Tigers (70-82), 5-3 | Municipal Stadium (33-42) | 57-95 | |
| » Starters: Frank Lary vs Dick Hall | Seventh | 38 out |
| Saturday, October 1 |
| » Lost to Tigers (71-82), 6-4 | Municipal Stadium (33-43) | 57-96 | Lost 2 |
| » Starters: Bob Bruce vs Bud Daley | Eighth | 39 out |
| Sunday, October 2 |
| » Defeated Tigers (71-83), 2-1 | Municipal Stadium (34-43) | 58-96 | |
| » Starters: Phil Regan vs Ray Herbert | Eighth | 39 out |
| Future Athletic Ernest Riles is born in Cairo, GA. |
| Thursday, October 20 |
| Former Athletic Lew Groh dies in Rochester, NY at the age of 78. |
| Tuesday, October 25 |
| Future Athletic Kelly Downs is born in Ogden, UT. |
| Monday, October 31 |
| Future Athletic Mike Gallego is born in Whittier, CA. |
| Saturday, November 12 |
| Future Athletic Donnie Hill is born in Pomona, CA. |
| Saturday, December 3 |
| Future Athletic Gene Nelson is born in Tampa, FL. |
| Saturday, December 10 |
| Future Athletic Jeff Bettendorf is born in Lompoc, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |
