| Sunday, January 11 |
| Future Red Lloyd McClendon is born in Gary, IN. |
| Wednesday, January 14 |
| Former Red John Ganzel dies in Orlando, FL at the age of 85. |
| Wednesday, February 4 |
| Future Red Pat Perry is born in Taylorville, IL. |
| Thursday, February 12 |
| Former Red Dode Paskert dies in Cleveland, OH at the age of 78. |
| Friday, February 20 |
| Future Red Bill Gullickson is born in Marshall, MN. |
| Thursday, April 9 |
| » Defeated Pirates (0-1), 4-1 | Crosley Field (1-0) | 1-0 | |
| » Starters: Ron Kline vs Bob Purkey | First | -- |
| Friday, April 10 |
| » Lost to Phillies (1-0), 2-1 | Shibe Park (0-1) | 1-1 | |
| » Starters: Don Newcombe vs Robin Roberts | Third | ½ out |
| » Major-league debuts: Sparky Anderson (Phillies) |
| Tuesday, April 14 |
| » Defeated Pirates (0-4), 3-2 | Crosley Field (2-0) | 2-1 | |
| » Starters: George Witt vs Bob Purkey | Third | 1 out |
| Wednesday, April 15 |
| » Defeated Pirates (0-5), 10-5 | Crosley Field (3-0) | 3-1 | Won 2 |
| » Starters: Bob Friend vs Joe Nuxhall | Third | ½ out |
| » Major-league debuts: Freddie Green (Pirates) |
| Friday, April 17 |
| » Lost to Phillies (2-2), 5-1 | Crosley Field (3-1) | 3-2 | |
| » Starters: Ruben Gomez vs Brooks Lawrence | Third | 1½ out |
| Saturday, April 18 |
| » Lost to Phillies (3-2), 14-9 | Crosley Field (3-2) | 3-3 | Lost 2 |
| » Starters: Seth Morehead vs Don Newcombe | Fifth | 1½ out |
| » Major-league debuts: Mike Cuellar (Reds) |
| Future Red Dennis Rasmussen is born in Los Angeles, CA. |
| Sunday, April 19 |
| » Defeated Phillies (3-3), 12-5 | Crosley Field (4-2) | 4-3 | |
| » Starters: Jim Owens vs Jim O'Toole | Fourth | 1 out |
| » Major-league debuts: Chris Short (Phillies) |
| Tuesday, April 21 |
| » Lost to Braves (5-1), 7-4 | County Stadium (0-1) | 4-4 | |
| » Starters: Bob Purkey vs Warren Spahn | Sixth | 2 out |
| Wednesday, April 22 |
| » Lost to Pirates (2-5), 9-8 | Forbes Field (0-1) | 4-5 | Lost 2 |
| » Starters: Joe Nuxhall vs Bob Friend | Fifth | 3 out |
| Thursday, April 23 |
| » Defeated Pirates (2-6), 5-2 | Forbes Field (1-1) | 5-5 | |
| » Starters: Brooks Lawrence vs George Witt | Sixth | 2 out |
| Friday, April 24 |
| » Lost to Braves (7-2), 10-7 | Crosley Field (4-3) | 5-6 | |
| » Starters: Joey Jay vs Don Newcombe | Fifth | 3 out |
| Saturday, April 25 |
| » Defeated Braves (7-3), 7-6 | Crosley Field (5-3) | 6-6 | |
| » Starters: Warren Spahn vs Bob Purkey | Fifth | 2 out |
| Sunday, April 26 |
| » Defeated Braves (7-4), 11-10 | Crosley Field (6-3) | 7-6 | Won 2 |
| » Starters: Lew Burdette vs Joe Nuxhall | Fourth | 1½ out |
| » Major-league debuts: Bob Hartman (Braves) |
| Wednesday, April 29 |
| » Defeated Cubs (7-8), 18-8 | Crosley Field (7-3) | 8-6 | Won 3 |
| » Starters: Moe Drabowsky vs Brooks Lawrence | Third | 1 out |
| Thursday, April 30 |
| » Lost to Cubs (8-8), 3-2 | Crosley Field (7-4) | 8-7 | |
| » Starters: Bob Anderson vs Bob Purkey | Fourth | 2 out |
| Friday, May 1 |
| » Defeated Dodgers (11-7), 5-3 | Crosley Field (8-4) | 9-7 | |
| » Starters: Don Drysdale vs Orlando Pena | Fourth | 1 out |
| Saturday, May 2 |
| » Defeated Dodgers (11-8), 16-4 | Crosley Field (9-4) | 10-7 | Won 2 |
| » Starters: Gene Snyder vs Jim O'Toole | Third | ½ out |
| Sunday, May 3 |
| » Defeated Dodgers (11-9), 6-3 | Crosley Field (10-4) | 11-7 | Won 3 |
| » Starters: Stan Williams vs Brooks Lawrence | Second | 1½ out |
| » Lost to Dodgers (12-9), 7-1 | Crosley Field (10-5) | 11-8 | |
| » Starters: Danny McDevitt vs Joe Nuxhall | Second | 1½ out |
| Monday, May 4 |
| » Lost to Giants (12-8), 6-5 | Crosley Field (10-6) | 11-9 | Lost 2 |
| » Starters: Mike McCormick vs Bob Purkey | Fourth | 1 out |
| Tuesday, May 5 |
| » Defeated Giants (12-9), 5-2 | Crosley Field (11-6) | 12-9 | |
| » Starters: Sam Jones vs Don Newcombe | Second | 1½ out |
| Friday, May 8 |
| » Defeated Braves (12-8), 3-2 | County Stadium (1-1) | 13-9 | Won 2 |
| » Starters: Brooks Lawrence vs Lew Burdette | Second | 1 out |
| Saturday, May 9 |
| » Defeated Braves (12-9), 3-0 | County Stadium (2-1) | 14-9 | Won 3 |
| » Starters: Bob Purkey vs Warren Spahn | First | -- |
| Sunday, May 10 |
| » Lost to Braves (13-9), 12-4 | County Stadium (2-2) | 14-10 | |
| » Starters: Don Newcombe vs Bob Rush | Third | 1 out |
| » Lost to Braves (14-9), 2-1 | County Stadium (2-3) | 14-11 | Lost 2 |
| » Starters: Joe Nuxhall vs Carl Willey | Third | 1 out |
| Tuesday, May 12 |
| » Lost to Cardinals (11-18), 7-4 | Sportsman's Park III (0-1) | 14-12 | Lost 3 |
| » Starters: Brooks Lawrence vs Gary Blaylock | Third | 2 out |
| Wednesday, May 13 |
| » Lost to Cubs (16-15), 10-0 | Wrigley Field (0-1) | 14-13 | Lost 4 |
| » Starters: Bob Purkey vs Glen Hobbie | Fourth | 2½ out |
| Thursday, May 14 |
| » Defeated Cubs (16-16), 2-0 | Wrigley Field (1-1) | 15-13 | |
| » Starters: Joe Nuxhall vs Dave Hillman | Fourth | 2½ out |
| Friday, May 15 |
| » Defeated Giants (16-14), 5-2 | Seals Stadium (1-0) | 16-13 | Won 2 |
| » Starters: Don Newcombe vs Jack Sanford | Third | 2 out |
| Saturday, May 16 |
| » Lost to Giants (17-14), 9-2 | Seals Stadium (1-1) | 16-14 | |
| » Starters: Brooks Lawrence vs Johnny Antonelli | Fourth | 3 out |
| Sunday, May 17 |
| » Lost to Giants (18-14), 9-1 | Seals Stadium (1-2) | 16-15 | Lost 2 |
| » Starters: Bob Purkey vs Stu Miller | Fourth | 4 out |
| Monday, May 18 |
| » Defeated Dodgers (18-17), 9-7 | Los Angeles Memorial Coliseum (1-0) | 17-15 | |
| » Starters: Bob Mabe vs Stan Williams | Third | 4 out |
| Former Red Gene Packard dies in Riverside, CA at the age of 72. |
| Tuesday, May 19 |
| » Lost to Dodgers (19-17), 6-4 | Los Angeles Memorial Coliseum (1-1) | 17-16 | |
| » Starters: Willard Schmidt vs Johnny Podres | Fourth | 5 out |
| Wednesday, May 20 |
| » Lost to Dodgers (20-17), 8-4 | Los Angeles Memorial Coliseum (1-2) | 17-17 | Lost 2 |
| » Starters: Brooks Lawrence vs Danny McDevitt | Fifth | 4½ out |
| » Defeated Dodgers (20-18), 7-5 | Los Angeles Memorial Coliseum (2-2) | 18-17 | |
| » Starters: Don Newcombe vs Carl Erskine | Fifth | 4½ out |
| Friday, May 22 |
| » Lost to Pirates (18-19), 4-3 | Forbes Field (1-2) | 18-18 | |
| » Starters: Bob Purkey vs Vern Law | Fifth | 5½ out |
| Saturday, May 23 |
| » Lost to Pirates (19-19), 6-5 | Forbes Field (1-3) | 18-19 | Lost 2 |
| » Starters: Orlando Pena vs Bennie Daniels | Sixth | 5½ out |
| Sunday, May 24 |
| » Lost to Pirates (20-19), 2-1 | Forbes Field (1-4) | 18-20 | Lost 3 |
| » Starters: Brooks Lawrence vs Ron Kline | Sixth | 6½ out |
| » Lost to Pirates (21-19), 5-4 | Forbes Field (1-5) | 18-21 | Lost 4 |
| » Starters: Willard Schmidt vs Bob Friend | Sixth | 6½ out |
| Monday, May 25 |
| Former Red Dave Brain dies in Los Angeles, CA at the age of 81. |
| Tuesday, May 26 |
| » Defeated Phillies (15-25), 2-1 | Crosley Field (12-6) | 19-21 | |
| » Starters: Ruben Gomez vs Don Newcombe | Sixth | 6 out |
| Future Red Dann Bilardello is born in Santa Cruz, CA. |
| Wednesday, May 27 |
| » Defeated Phillies (15-26), 10-4 | Crosley Field (13-6) | 20-21 | Won 2 |
| » Starters: Robin Roberts vs Bob Purkey | Fifth | 6 out |
| Thursday, May 28 |
| » Lost to Phillies (16-26), 4-3 | Crosley Field (13-7) | 20-22 | |
| » Starters: Jim Owens vs Joe Nuxhall | Sixth | 6 out |
| Friday, May 29 |
| » Defeated Pirates (22-22), 8-5 | Crosley Field (14-7) | 21-22 | |
| » Starters: Ron Kline vs Brooks Lawrence | Sixth | 6 out |
| Saturday, May 30 |
| » Lost to Pirates (23-22), 3-1 | Crosley Field (14-8) | 21-23 | |
| » Starters: Bennie Daniels vs Jim O'Toole | Sixth | 7 out |
| Sunday, May 31 |
| » Lost to Pirates (24-22), 6-2 | Crosley Field (14-9) | 21-24 | Lost 2 |
| » Starters: Vern Law vs Bob Purkey | Sixth | 8 out |
| » Lost to Pirates (25-22), 14-11 | Crosley Field (14-10) | 21-25 | Lost 3 |
| » Starters: Al Jackson vs Don Newcombe | Sixth | 8 out |
| Tuesday, June 2 |
| » Defeated Dodgers (25-24), 5-4 | Crosley Field (15-10) | 22-25 | |
| » Starters: Don Drysdale vs Brooks Lawrence | Sixth | 7½ out |
| Wednesday, June 3 |
| » Lost to Dodgers (26-24), 5-1 | Crosley Field (15-11) | 22-26 | |
| » Starters: Stan Williams vs Orlando Pena | Sixth | 8½ out |
| Thursday, June 4 |
| » Defeated Dodgers (26-25), 5-3 | Crosley Field (16-11) | 23-26 | |
| » Starters: Danny McDevitt vs Joe Nuxhall | Sixth | 7½ out |
| Friday, June 5 |
| » Defeated Giants (28-22), 7-2 | Crosley Field (17-11) | 24-26 | Won 2 |
| » Starters: Johnny Antonelli vs Don Newcombe | Sixth | 6½ out |
| Saturday, June 6 |
| » Lost to Giants (29-22), 13-3 | Crosley Field (17-12) | 24-27 | |
| » Starters: Sam Jones vs Bob Purkey | Sixth | 6½ out |
| Sunday, June 7 |
| » Lost to Giants (30-22), 5-3 | Crosley Field (17-13) | 24-28 | Lost 2 |
| » Starters: Jack Sanford vs Brooks Lawrence | Fifth | 7 out |
| » Defeated Giants (30-23), 7-1 | Crosley Field (18-13) | 25-28 | |
| » Starters: Mike McCormick vs Orlando Pena | Fifth | 7 out |
| Tuesday, June 9 |
| » Lost to Cubs (29-26), 8-4 | Wrigley Field (1-2) | 25-29 | |
| » Starters: Joe Nuxhall vs Bob Anderson | Fifth | 7½ out |
| Wednesday, June 10 |
| » Defeated Cubs (29-27), 6-4 | Wrigley Field (2-2) | 26-29 | |
| » Starters: Bob Purkey vs Glen Hobbie | Fifth | 6½ out |
| Thursday, June 11 |
| » Defeated Cubs (29-28), 8-0 | Wrigley Field (3-2) | 27-29 | Won 2 |
| » Starters: Don Newcombe vs Moe Drabowsky | Sixth | 6½ out |
| Friday, June 12 |
| » Lost to Cardinals (23-32), 2-1 | Sportsman's Park III (0-2) | 27-30 | |
| » Starters: Brooks Lawrence vs Ernie Broglio | Sixth | 6½ out |
| Saturday, June 13 |
| » Lost to Cardinals (24-32), 7-0 | Sportsman's Park III (0-3) | 27-31 | Lost 2 |
| » Starters: Orlando Pena vs Larry Jackson | Sixth | 7½ out |
| Sunday, June 14 |
| » Lost to Cardinals (25-32), 5-4 | Sportsman's Park III (0-4) | 27-32 | Lost 3 |
| » Starters: Joe Nuxhall vs Gary Blaylock | Sixth | 7 out |
| » Defeated Cardinals (25-33), 3-2 | Sportsman's Park III (1-4) | 28-32 | |
| » Starters: Jim Brosnan vs Dick Ricketts | Sixth | 7 out |
| » Major-league debuts: Dick Ricketts (Cardinals) |
| Tuesday, June 16 |
| » Defeated Giants (34-28), 2-1 | Seals Stadium (2-2) | 29-32 | Won 2 |
| » Starters: Don Newcombe vs Mike McCormick | Sixth | 6½ out |
| Wednesday, June 17 |
| » Lost to Giants (35-28), 7-5 | Seals Stadium (2-3) | 29-33 | |
| » Starters: Orlando Pena vs Johnny Antonelli | Sixth | 6 out |
| Thursday, June 18 |
| » Lost to Giants (36-28), 8-3 | Seals Stadium (2-4) | 29-34 | Lost 2 |
| » Starters: Joe Nuxhall vs Al Worthington | Sixth | 7 out |
| Friday, June 19 |
| » Lost to Dodgers (35-32), 6-2 | Los Angeles Memorial Coliseum (2-3) | 29-35 | Lost 3 |
| » Starters: Brooks Lawrence vs Roger Craig | Sixth | 7½ out |
| Saturday, June 20 |
| » Lost to Dodgers (36-32), 9-2 | Los Angeles Memorial Coliseum (2-4) | 29-36 | Lost 4 |
| » Starters: Bob Purkey vs Don Drysdale | Seventh | 8 out |
| Sunday, June 21 |
| » Defeated Dodgers (36-33), 17-3 | Los Angeles Memorial Coliseum (3-4) | 30-36 | |
| » Starters: Don Newcombe vs Johnny Podres | Seventh | 8 out |
| Tuesday, June 23 |
| » Lost to Cubs (34-33), 3-1 | Crosley Field (18-14) | 30-37 | |
| » Starters: Glen Hobbie vs Joe Nuxhall | Sixth | 9 out |
| Wednesday, June 24 |
| » Defeated Cubs (34-34), 5-0 | Crosley Field (19-14) | 31-37 | |
| » Starters: Dick Drott vs Jim Brosnan | Sixth | 9 out |
| Thursday, June 25 |
| » Lost to Cubs (35-34), 6-2 | Crosley Field (19-15) | 31-38 | |
| » Starters: Bob Anderson vs Bob Purkey | Seventh | 9 out |
| Friday, June 26 |
| » Defeated Cardinals (31-38), 7-6 | Crosley Field (20-15) | 32-38 | |
| » Starters: Larry Jackson vs Don Newcombe | Sixth | 9 out |
| Saturday, June 27 |
| » Lost to Cardinals (32-38), 5-0 | Crosley Field (20-16) | 32-39 | |
| » Starters: Ernie Broglio vs Jim O'Toole | Seventh | 9 out |
| Sunday, June 28 |
| » Lost to Cardinals (33-38), 9-7 | Crosley Field (20-17) | 32-40 | Lost 2 |
| » Starters: Marshall Bridges vs Joe Nuxhall | Seventh | 10½ out |
| » Lost to Cardinals (34-38), 11-8 | Crosley Field (20-18) | 32-41 | Lost 3 |
| » Starters: Dick Ricketts vs Willard Schmidt | Seventh | 10½ out |
| Tuesday, June 30 |
| » Defeated Braves (42-31), 8-5 | Crosley Field (21-18) | 33-41 | |
| » Starters: Lew Burdette vs Bob Purkey | Seventh | 9½ out |
| Thursday, July 2 |
| » Lost to Phillies (28-46), 7-6 | Shibe Park (0-2) | 33-42 | |
| » Starters: Jim Brosnan vs Don Cardwell | Seventh | 9 out |
| » Defeated Phillies (28-47), 8-4 | Shibe Park (1-2) | 34-42 | |
| » Starters: Don Newcombe vs Ruben Gomez | Seventh | 9 out |
| Friday, July 3 |
| » Defeated Phillies (28-48), 6-1 | Shibe Park (2-2) | 35-42 | Won 2 |
| » Starters: Jim O'Toole vs Jim Owens | Seventh | 9 out |
| Saturday, July 4 |
| » Lost to Pirates (42-39), 4-3 | Forbes Field (1-6) | 35-43 | |
| » Starters: Joe Nuxhall vs Bob Friend | Seventh | 9½ out |
| Sunday, July 5 |
| » Lost to Pirates (43-39), 7-5 | Forbes Field (1-7) | 35-44 | Lost 2 |
| » Starters: Bob Purkey vs Harvey Haddix | Seventh | 10½ out |
| » Lost to Pirates (44-39), 3-2 | Forbes Field (1-8) | 35-45 | Lost 3 |
| » Starters: Jim Brosnan vs Ron Kline | Seventh | 10½ out |
| Thursday, July 9 |
| » Lost to Giants (47-35), 3-2 | Crosley Field (21-19) | 35-46 | Lost 4 |
| » Manager: Fred Hutchinson |
| » Starters: Mike McCormick vs Don Newcombe | Seventh | 11½ out |
| Friday, July 10 |
| » Lost to Giants (48-35), 8-6 | Crosley Field (21-20) | 35-47 | Lost 5 |
| » Starters: Stu Miller vs Jim O'Toole | Sixth | 12½ out |
| Saturday, July 11 |
| » Lost to Giants (49-35), 5-3 | Crosley Field (21-21) | 35-48 | Lost 6 |
| » Starters: Johnny Antonelli vs Jim Brosnan | Sixth | 13½ out |
| Sunday, July 12 |
| » Defeated Dodgers (49-38), 4-3 | Crosley Field (22-21) | 36-48 | |
| » Starters: Larry Sherry vs Bob Purkey | Sixth | 12½ out |
| Monday, July 13 |
| » Defeated Dodgers (49-39), 13-5 | Crosley Field (23-21) | 37-48 | Won 2 |
| » Starters: Danny McDevitt vs Joe Nuxhall | Sixth | 11½ out |
| Tuesday, July 14 |
| » Lost to Cardinals (42-44), 6-5 | Sportsman's Park III (1-5) | 37-49 | |
| » Starters: Don Newcombe vs Larry Jackson | Sixth | 12 out |
| Wednesday, July 15 |
| » Defeated Cardinals (42-45), 11-5 | Sportsman's Park III (2-5) | 38-49 | |
| » Starters: Jim O'Toole vs Vinegar Bend Mizell | Seventh | 11½ out |
| Thursday, July 16 |
| » Defeated Cardinals (42-46), 7-5 | Sportsman's Park III (3-5) | 39-49 | Won 2 |
| » Starters: Jim Brosnan vs Ernie Broglio | Seventh | 11 out |
| Former Red Jimmy Ripple dies in Greensburg, PA at the age of 50. |
| Friday, July 17 |
| » Lost to Cubs (45-44), 1-0 | Wrigley Field (3-3) | 39-50 | |
| » Starters: Bob Purkey vs Art Ceccarelli | Seventh | 12 out |
| Saturday, July 18 |
| » Defeated Cubs (45-45), 5-1 | Wrigley Field (4-3) | 40-50 | |
| » Starters: Jay Hook vs John Buzhardt | Seventh | 12 out |
| Monday, July 20 |
| Former Red Morrie Arnovich dies in Superior, WI at the age of 49. |
| Tuesday, July 21 |
| » Defeated Braves (46-42), 12-2 | County Stadium (3-3) | 41-50 | Won 2 |
| » Starters: Don Newcombe vs Lew Burdette | Seventh | 10 out |
| Wednesday, July 22 |
| » Lost to Braves (47-42), 5-4 | County Stadium (3-4) | 41-51 | |
| » Starters: Jim O'Toole vs Warren Spahn | Seventh | 11 out |
| Former Red Ralph Savidge dies in Berwick, PA at the age of 81. |
| Thursday, July 23 |
| » Defeated Braves (47-43), 6-2 | County Stadium (4-4) | 42-51 | |
| » Starters: Bob Purkey vs Joey Jay | Seventh | 11 out |
| Friday, July 24 |
| » Lost to Phillies (38-55), 2-1 | Crosley Field (23-22) | 42-52 | |
| » Starters: Jim Owens vs Jay Hook | Seventh | 12 out |
| Saturday, July 25 |
| » Lost to Phillies (39-55), 6-3 | Crosley Field (23-23) | 42-53 | Lost 2 |
| » Starters: Don Cardwell vs Joe Nuxhall | Seventh | 12 out |
| Sunday, July 26 |
| » Defeated Phillies (39-56), 4-2 | Crosley Field (24-23) | 43-53 | |
| » Starters: Robin Roberts vs Don Newcombe | Seventh | 11½ out |
| » Lost to Phillies (40-56), 6-3 | Crosley Field (24-24) | 43-54 | |
| » Starters: Gene Conley vs Jim O'Toole | Seventh | 11½ out |
| Monday, July 27 |
| » Defeated Cardinals (48-51), 8-3 | Crosley Field (25-24) | 44-54 | |
| » Starters: Vinegar Bend Mizell vs Bob Purkey | Seventh | 11 out |
| Tuesday, July 28 |
| » Defeated Cardinals (48-52), 6-4 | Crosley Field (26-24) | 45-54 | Won 2 |
| » Starters: Ernie Broglio vs Jay Hook | Seventh | 10 out |
| Wednesday, July 29 |
| » Defeated Cardinals (48-53), 9-2 | Crosley Field (27-24) | 46-54 | Won 3 |
| » Starters: Larry Jackson vs Joe Nuxhall | Seventh | 9½ out |
| Thursday, July 30 |
| » Lost to Cardinals (49-53), 1-0 | Crosley Field (27-25) | 46-55 | |
| » Starters: Bob Gibson vs Jim O'Toole | Seventh | 10 out |
| Friday, July 31 |
| » Defeated Cubs (50-51), 5-4 | Crosley Field (28-25) | 47-55 | |
| » Starters: Bob Anderson vs Don Newcombe | Seventh | 10 out |
| Saturday, August 1 |
| » Defeated Cubs (50-52), 12-3 | Crosley Field (29-25) | 48-55 | Won 2 |
| » Starters: Glen Hobbie vs Bob Purkey | Seventh | 10 out |
| Sunday, August 2 |
| » Defeated Cubs (50-53), 2-0 | Crosley Field (30-25) | 49-55 | Won 3 |
| » Starters: Dave Hillman vs Jay Hook | Sixth | 10 out |
| Tuesday, August 4 |
| » Defeated Dodgers (60-48), 4-1 | Los Angeles Memorial Coliseum (4-4) | 50-55 | Won 4 |
| » Starters: Joe Nuxhall vs Stan Williams | Sixth | 9 out |
| Wednesday, August 5 |
| » Lost to Dodgers (61-48), 6-3 | Los Angeles Memorial Coliseum (4-5) | 50-56 | |
| » Starters: Bob Purkey vs Johnny Podres | Fifth | 10 out |
| Friday, August 7 |
| » Lost to Giants (62-46), 3-2 | Seals Stadium (2-5) | 50-57 | Lost 2 |
| » Starters: Jim O'Toole vs Johnny Antonelli | Sixth | 11½ out |
| Saturday, August 8 |
| » Defeated Giants (62-47), 9-6 | Seals Stadium (3-5) | 51-57 | |
| » Starters: Jay Hook vs Mike McCormick | Seventh | 10½ out |
| Sunday, August 9 |
| » Lost to Giants (63-47), 4-3 | Seals Stadium (3-6) | 51-58 | |
| » Starters: Don Newcombe vs Jack Sanford | Seventh | 11½ out |
| Tuesday, August 11 |
| » Defeated Braves (59-49), 4-3 | Crosley Field (31-25) | 52-58 | |
| » Starters: Warren Spahn vs Joe Nuxhall | Sixth | 12½ out |
| » Lost to Braves (60-49), 7-3 | Crosley Field (31-26) | 52-59 | |
| » Starters: Lew Burdette vs Jay Hook | Sixth | 12½ out |
| Wednesday, August 12 |
| » Lost to Braves (61-49), 6-4 | Crosley Field (31-27) | 52-60 | Lost 2 |
| » Starters: Juan Pizarro vs Jim O'Toole | Seventh | 13 out |
| Former Red Mike O'Neill dies in Scranton, PA at the age of 82. |
| Thursday, August 13 |
| » Defeated Braves (61-50), 9-8 | Crosley Field (32-27) | 53-60 | |
| » Starters: Bob Buhl vs Jim Brosnan | Sixth | 12 out |
| Friday, August 14 |
| » Defeated Phillies (47-66), 15-13 | Shibe Park (3-2) | 54-60 | Won 2 |
| » Starters: Don Newcombe vs Gene Conley | Sixth | 10½ out |
| » Defeated Phillies (47-67), 5-4 | Shibe Park (4-2) | 55-60 | Won 3 |
| » Starters: Willard Schmidt vs Jim Owens | Sixth | 10½ out |
| Future Red Don Carman is born in Oklahoma City, OK. |
| Saturday, August 15 |
| » Defeated Phillies (47-68), 8-3 | Shibe Park (5-2) | 56-60 | Won 4 |
| » Starters: Joe Nuxhall vs Ray Semproch | Sixth | 10½ out |
| Sunday, August 16 |
| » Lost to Phillies (48-68), 8-5 | Shibe Park (5-3) | 56-61 | |
| » Starters: Bob Purkey vs Robin Roberts | Sixth | 11 out |
| » Lost to Phillies (49-68), 6-0 | Shibe Park (5-4) | 56-62 | Lost 2 |
| » Starters: Jay Hook vs Don Cardwell | Sixth | 11 out |
| Monday, August 17 |
| » Lost to Giants (67-50), 6-3 | Crosley Field (32-28) | 56-63 | Lost 3 |
| » Starters: Mike McCormick vs Jim O'Toole | Sixth | 12 out |
| Tuesday, August 18 |
| » Defeated Giants (67-51), 7-0 | Crosley Field (33-28) | 57-63 | |
| » Starters: Eddie Fisher vs Don Newcombe | Sixth | 11 out |
| Wednesday, August 19 |
| » Defeated Dodgers (66-55), 9-4 | Crosley Field (34-28) | 58-63 | Won 2 |
| » Starters: Sandy Koufax vs Joe Nuxhall | Sixth | 10 out |
| Thursday, August 20 |
| » Lost to Dodgers (67-55), 8-5 | Crosley Field (34-29) | 58-64 | |
| » Starters: Danny McDevitt vs Bob Purkey | Sixth | 11 out |
| Friday, August 21 |
| » Defeated Cardinals (57-68), 2-1 | Crosley Field (35-29) | 59-64 | |
| » Starters: Larry Jackson vs Jay Hook | Sixth | 11½ out |
| Saturday, August 22 |
| » Defeated Cardinals (57-69), 11-4 | Crosley Field (36-29) | 60-64 | Won 2 |
| » Starters: Vinegar Bend Mizell vs Jim O'Toole | Fifth | 11½ out |
| Sunday, August 23 |
| » Defeated Cardinals (57-70), 5-3 | Crosley Field (37-29) | 61-64 | Won 3 |
| » Starters: Bob Miller vs Don Newcombe | Fifth | 11 out |
| Tuesday, August 25 |
| » Lost to Cubs (60-64), 8-6 | Crosley Field (37-30) | 61-65 | |
| » Starters: John Buzhardt vs Bob Purkey | Sixth | 11½ out |
| Wednesday, August 26 |
| » Lost to Cubs (61-64), 9-5 | Crosley Field (37-31) | 61-66 | Lost 2 |
| » Starters: Glen Hobbie vs Jay Hook | Sixth | 11½ out |
| Thursday, August 27 |
| » Defeated Cubs (61-65), 5-0 | Crosley Field (38-31) | 62-66 | |
| » Starters: Art Ceccarelli vs Jim O'Toole | Sixth | 10 out |
| Friday, August 28 |
| » Lost to Cardinals (60-71), 3-2 | Sportsman's Park III (3-6) | 62-67 | |
| » Starters: Don Newcombe vs Ernie Broglio | Fifth | 11 out |
| Saturday, August 29 |
| » Lost to Cardinals (61-71), 7-3 | Sportsman's Park III (3-7) | 62-68 | Lost 2 |
| » Starters: Bob Purkey vs Bob Miller | Fifth | 11½ out |
| Sunday, August 30 |
| » Defeated Cardinals (61-72), 6-4 | Sportsman's Park III (4-7) | 63-68 | |
| » Starters: Jay Hook vs Bob Gibson | Sixth | 10½ out |
| Wednesday, September 2 |
| » Defeated Pirates (70-63), 6-3 | Crosley Field (39-31) | 64-68 | Won 2 |
| » Starters: Vern Law vs Jim O'Toole | Fifth | 9½ out |
| » Defeated Pirates (70-64), 2-1 | Crosley Field (40-31) | 65-68 | Won 3 |
| » Starters: Bob Friend vs Don Newcombe | Fifth | 9½ out |
| Friday, September 4 |
| » Lost to Braves (71-62), 4-1 | Crosley Field (40-32) | 65-69 | |
| » Starters: Warren Spahn vs Bob Purkey | Fifth | 10 out |
| Saturday, September 5 |
| » Defeated Braves (71-63), 5-1 | Crosley Field (41-32) | 66-69 | |
| » Starters: Bob Rush vs Jay Hook | Fifth | 10 out |
| Sunday, September 6 |
| » Lost to Braves (72-63), 6-2 | Crosley Field (41-33) | 66-70 | |
| » Starters: Juan Pizarro vs Jim O'Toole | Sixth | 10 out |
| Monday, September 7 |
| » Lost to Phillies (59-80), 6-4 | Crosley Field (41-34) | 66-71 | Lost 2 |
| » Starters: Humberto Robinson vs Don Newcombe | Fourth | 11 out |
| Tuesday, September 8 |
| Former Red Roy Mitchell dies in Temple, TX at the age of 75. |
| Wednesday, September 9 |
| » Defeated Cubs (65-71), 4-2 | Wrigley Field (5-3) | 67-71 | |
| » Starters: Bob Purkey vs Glen Hobbie | Fourth | 10½ out |
| » Defeated Cubs (65-72), 7-2 | Wrigley Field (6-3) | 68-71 | Won 2 |
| » Starters: Jay Hook vs Dave Hillman | Fourth | 10½ out |
| » Major-league debuts: Cliff Cook and Buddy Gilbert (Reds) |
| Future Red Tom Foley is born in Columbus, GA. |
| Thursday, September 10 |
| » Defeated Cubs (65-73), 10-4 | Wrigley Field (7-3) | 69-71 | Won 3 |
| » Starters: Jim O'Toole vs Art Ceccarelli | Fourth | 10 out |
| » Lost to Cubs (66-73), 6-3 | Wrigley Field (7-4) | 69-72 | |
| » Starters: Jim Bailey vs Ben Johnson | Fourth | 10 out |
| » Major-league debuts: Jim Bailey (Reds) |
| Friday, September 11 |
| » Lost to Braves (77-63), 10-2 | County Stadium (4-5) | 69-73 | Lost 2 |
| » Starters: Jay Hook vs Joey Jay | Fifth | 10 out |
| Saturday, September 12 |
| » Lost to Braves (78-63), 4-3 | County Stadium (4-6) | 69-74 | Lost 3 |
| » Starters: Don Newcombe vs Lew Burdette | Fourth | 11 out |
| Future Red Scotti Madison is born in Pensacola, FL. |
| Sunday, September 13 |
| » Defeated Braves (78-64), 3-2 | County Stadium (5-6) | 70-74 | |
| » Starters: Bob Purkey vs Warren Spahn | Fourth | 11 out |
| Monday, September 14 |
| » Defeated Giants (80-63), 4-1 | Seals Stadium (4-6) | 71-74 | Won 2 |
| » Starters: Jim Brosnan vs Johnny Antonelli | Fifth | 10 out |
| Tuesday, September 15 |
| » Lost to Giants (81-63), 13-6 | Seals Stadium (4-7) | 71-75 | |
| » Starters: Jay Hook vs Mike McCormick | Fourth | 11 out |
| Wednesday, September 16 |
| » Defeated Dodgers (79-66), 7-4 | Los Angeles Memorial Coliseum (5-5) | 72-75 | |
| » Starters: Orlando Pena vs Sandy Koufax | Fifth | 10 out |
| Thursday, September 17 |
| » Lost to Dodgers (80-66), 4-3 | Los Angeles Memorial Coliseum (5-6) | 72-76 | |
| » Starters: Bob Purkey vs Danny McDevitt | Fourth | 11 out |
| Saturday, September 19 |
| » Lost to Pirates (76-72), 4-3 | Forbes Field (1-9) | 72-77 | Lost 2 |
| » Starters: Don Newcombe vs Dick Hall | Fourth | 10½ out |
| Sunday, September 20 |
| » Lost to Pirates (77-72), 10-1 | Forbes Field (1-10) | 72-78 | Lost 3 |
| » Starters: Jim Brosnan vs Vern Law | Fifth | 11½ out |
| Tuesday, September 22 |
| » Lost to Phillies (62-88), 3-1 | Shibe Park (5-5) | 72-79 | Lost 4 |
| » Starters: Orlando Pena vs Jim Owens | Sixth | 13 out |
| » Lost to Phillies (63-88), 3-2 | Shibe Park (5-6) | 72-80 | Lost 5 |
| » Starters: Bob Purkey vs Humberto Robinson | Sixth | 13 out |
| Saturday, September 26 |
| » Defeated Pirates (78-75), 7-6 | Crosley Field (42-34) | 73-80 | |
| » Starters: Jim Umbricht vs Jim O'Toole | Fifth | 12 out |
| » Major-league debuts: Jim Umbricht (Pirates) |
| Sunday, September 27 |
| » Defeated |
