| Wednesday, March 11 |
| Future Oriole Phil Bradley is born in Bloomington, IN. |
| Sunday, March 15 |
| Future Oriole Harold Baines is born in Easton, MD. |
| Thursday, April 9 |
| » Lost to Senators (1-0), 9-2 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Jack Harshman vs Pedro Ramos | Third | 1 out |
| Tuesday, April 14 |
| » Lost to Yankees (2-0), 13-3 | Memorial Stadium (0-1) | 0-2 | Lost 2 |
| » Starters: Don Larsen vs Arnie Portocarrero | Fifth | 3 out |
| » Major-league debuts: Jack Fisher (Orioles) |
| Wednesday, April 15 |
| » Lost to Yankees (3-0), 3-1 | Memorial Stadium (0-2) | 0-3 | Lost 3 |
| » Starters: Whitey Ford vs Hoyt Wilhelm | Seventh | 3½ out |
| Thursday, April 16 |
| » Defeated Yankees (3-1), 7-4 | Memorial Stadium (1-2) | 1-3 | |
| » Starters: Art Ditmar vs George Bamberger | Sixth | 3 out |
| Friday, April 17 |
| » Defeated Senators (2-3), 4-3 | Memorial Stadium (2-2) | 2-3 | Won 2 |
| » Starters: Bill Fischer vs Milt Pappas | Fourth | 3 out |
| Saturday, April 18 |
| » Defeated Senators (2-4), 6-1 | Memorial Stadium (3-2) | 3-3 | Won 3 |
| » Starters: Chuck Stobbs vs Jerry Walker | Fourth | 3 out |
| Future Oriole Rich Bordi is born in San Francisco, CA. |
| Sunday, April 19 |
| » Defeated Senators (2-5), 7-5 | Memorial Stadium (4-2) | 4-3 | Won 4 |
| » Starters: Camilo Pascual vs Billy O'Dell | Fourth | 2½ out |
| » Lost to Senators (3-5), 4-2 | Memorial Stadium (4-3) | 4-4 | |
| » Starters: Russ Kemmerer vs Jack Harshman | Fourth | 2½ out |
| » Major-league debuts: Wes Stock (Orioles) |
| Tuesday, April 21 |
| » Defeated Red Sox (4-4), 5-2 | Fenway Park (1-0) | 5-4 | |
| » Starters: Hoyt Wilhelm vs Jerry Casale | Third | 2½ out |
| Wednesday, April 22 |
| » Lost to Red Sox (5-4), 8-4 | Fenway Park (1-1) | 5-5 | |
| » Starters: Arnie Portocarrero vs Tom Brewer | Fifth | 3½ out |
| Thursday, April 23 |
| » Defeated Red Sox (5-5), 8-7 | Fenway Park (2-1) | 6-5 | |
| » Starters: Milt Pappas vs Ted Bowsfield | Third | 3½ out |
| Saturday, April 25 |
| » Defeated Yankees (6-5), 2-1 | Yankee Stadium (1-0) | 7-5 | Won 2 |
| » Starters: Jack Harshman vs Art Ditmar | Second | 3 out |
| Sunday, April 26 |
| » Defeated Yankees (6-6), 5-4 | Yankee Stadium (2-0) | 8-5 | Won 3 |
| » Starters: Billy O'Dell vs Tom Sturdivant | Second | 1 out |
| » Defeated Yankees (6-7), 3-2 | Yankee Stadium (3-0) | 9-5 | Won 4 |
| » Starters: Hoyt Wilhelm vs Duke Maas | Second | 1 out |
| Wednesday, April 29 |
| » Lost to Tigers (2-12), 7-1 | Tiger Stadium (0-1) | 9-6 | |
| » Starters: Arnie Portocarrero vs Frank Lary | Second | 1½ out |
| Thursday, April 30 |
| » Lost to Athletics (9-7), 4-3 | Municipal Stadium (0-1) | 9-7 | Lost 2 |
| » Starters: Jack Harshman vs Ned Garver | Third | 2 out |
| Friday, May 1 |
| » Lost to Athletics (10-7), 6-3 | Municipal Stadium (0-2) | 9-8 | Lost 3 |
| » Starters: Jerry Walker vs Bob Grim | Fourth | 3 out |
| Saturday, May 2 |
| » Defeated Athletics (10-8), 3-1 | Municipal Stadium (1-2) | 10-8 | |
| » Starters: Hoyt Wilhelm vs Ray Herbert | Third | 3 out |
| Sunday, May 3 |
| » Defeated White Sox (11-8), 4-2 | Comiskey Park I (1-0) | 11-8 | Won 2 |
| » Starters: Billy O'Dell vs Dick Donovan | Second | 2½ out |
| Future Oriole Tony Arnold is born in ElPaso, TX. |
| Tuesday, May 5 |
| » Lost to Indians (14-5), 9-1 | Cleveland Stadium (0-1) | 11-9 | |
| » Starters: Jack Harshman vs Don Ferrarese | Second | 3½ out |
| Wednesday, May 6 |
| » Defeated Indians (14-6), 6-5 | Cleveland Stadium (1-1) | 12-9 | |
| » Starters: Milt Pappas vs Gary Bell | Second | 2½ out |
| Thursday, May 7 |
| » Defeated Senators (13-11), 10-1 | Griffith Stadium (1-1) | 13-9 | Won 2 |
| » Starters: Jerry Walker vs Pedro Ramos | Second | 2 out |
| Friday, May 8 |
| » Lost to Red Sox (10-11), 5-0 | Memorial Stadium (4-4) | 13-10 | |
| » Starters: Frank Sullivan vs Billy O'Dell | Second | 3 out |
| Saturday, May 9 |
| » Defeated Red Sox (10-12), 4-3 | Memorial Stadium (5-4) | 14-10 | |
| » Starters: Billy Hoeft vs Hoyt Wilhelm | Second | 2 out |
| Sunday, May 10 |
| » Lost to Red Sox (11-12), 3-2 | Memorial Stadium (5-5) | 14-11 | |
| » Starters: Tom Brewer vs Arnie Portocarrero | Third | 2 out |
| » Lost to Red Sox (12-12), 5-1 | Memorial Stadium (5-6) | 14-12 | Lost 2 |
| » Starters: Frank Baumann vs Hal Brown | Third | 2 out |
| Monday, May 11 |
| » Defeated Senators (14-14), 7-3 | Griffith Stadium (2-1) | 15-12 | |
| » Starters: Milt Pappas vs Pedro Ramos | Third | 1½ out |
| Tuesday, May 12 |
| Future Oriole Kevin Bass is born in Redwood City, CA. |
| Thursday, May 14 |
| » Lost to Athletics (12-14), 2-1 | Memorial Stadium (5-7) | 15-13 | |
| » Starters: Ned Garver vs Billy O'Dell | Third | 2½ out |
| Friday, May 15 |
| » Defeated Tigers (10-18), 2-1 | Memorial Stadium (6-7) | 16-13 | |
| » Starters: Don Mossi vs Jerry Walker | Third | 2½ out |
| Saturday, May 16 |
| » Defeated Tigers (10-19), 6-1 | Memorial Stadium (7-7) | 17-13 | Won 2 |
| » Starters: Frank Lary vs Hoyt Wilhelm | Third | 2½ out |
| Sunday, May 17 |
| » Defeated Indians (18-10), 8-7 | Memorial Stadium (8-7) | 18-13 | Won 3 |
| » Starters: Cal McLish vs Arnie Portocarrero | Third | 2½ out |
| » Lost to Indians (19-10), 8-3 | Memorial Stadium (8-8) | 18-14 | |
| » Starters: Gary Bell vs Milt Pappas | Third | 2½ out |
| Monday, May 18 |
| » Defeated Indians (19-11), 3-0 | Memorial Stadium (9-8) | 19-14 | |
| » Starters: Don Ferrarese vs Hal Brown | Third | 2 out |
| Tuesday, May 19 |
| » Defeated White Sox (21-13), 2-1 | Memorial Stadium (10-8) | 20-14 | Won 2 |
| » Starters: Billy Pierce vs Billy O'Dell | Third | 1½ out |
| Wednesday, May 20 |
| » Lost to White Sox (22-13), 5-2 | Memorial Stadium (10-9) | 20-15 | |
| » Starters: Dick Donovan vs Jack Harshman | Third | 2½ out |
| Friday, May 22 |
| » Defeated Yankees (12-20), 5-0 | Memorial Stadium (11-9) | 21-15 | |
| » Starters: Bob Turley vs Hoyt Wilhelm | Third | 2½ out |
| Saturday, May 23 |
| » Lost to Yankees (13-20), 13-5 | Memorial Stadium (11-10) | 21-16 | |
| » Starters: Don Larsen vs Milt Pappas | Third | 2½ out |
| Sunday, May 24 |
| » Lost to Yankees (14-20), 9-0 | Memorial Stadium (11-11) | 21-17 | Lost 2 |
| » Starters: Whitey Ford vs Billy O'Dell | Third | 2½ out |
| » Defeated Yankees (14-21), 2-1 | Memorial Stadium (12-11) | 22-17 | |
| » Starters: Art Ditmar vs Jerry Walker | Third | 2½ out |
| Tuesday, May 26 |
| » Defeated Senators (19-22), 6-5 | Memorial Stadium (13-11) | 23-17 | Won 2 |
| » Starters: Russ Kemmerer vs Hal Brown | Third | 2½ out |
| Wednesday, May 27 |
| » Lost to Senators (20-22), 6-0 | Memorial Stadium (13-12) | 23-18 | |
| » Starters: Camilo Pascual vs Arnie Portocarrero | Third | 2½ out |
| Thursday, May 28 |
| » Defeated Yankees (15-23), 5-0 | Yankee Stadium (4-0) | 24-18 | |
| » Starters: Hoyt Wilhelm vs Ralph Terry | Third | 1½ out |
| Friday, May 29 |
| » Lost to Yankees (16-23), 5-2 | Yankee Stadium (4-1) | 24-19 | |
| » Starters: Ernie Johnson vs Whitey Ford | Third | 2 out |
| Saturday, May 30 |
| » Lost to Red Sox (18-23), 5-4 | Fenway Park (2-2) | 24-20 | Lost 2 |
| » Starters: Milt Pappas vs Tom Brewer | Third | 3 out |
| » Lost to Red Sox (19-23), 8-3 | Fenway Park (2-3) | 24-21 | Lost 3 |
| » Starters: Jerry Walker vs Ted Wills | Third | 3 out |
| Sunday, May 31 |
| » Defeated Red Sox (19-24), 2-1 | Fenway Park (3-3) | 25-21 | |
| » Starters: Hal Brown vs Ike Delock | Third | 2 out |
| Tuesday, June 2 |
| » Defeated White Sox (25-21), 3-2 | Comiskey Park I (2-0) | 26-21 | Won 2 |
| » Starters: Hoyt Wilhelm vs Bob Shaw | Second | 1½ out |
| Wednesday, June 3 |
| » Lost to White Sox (26-21), 6-1 | Comiskey Park I (2-1) | 26-22 | |
| » Starters: Billy O'Dell vs Billy Pierce | Third | 1½ out |
| Thursday, June 4 |
| » Lost to White Sox (27-21), 6-5 | Comiskey Park I (2-2) | 26-23 | Lost 2 |
| » Starters: Jack Harshman vs Dick Donovan | Third | 1½ out |
| Friday, June 5 |
| » Defeated Athletics (23-23), 6-1 | Municipal Stadium (2-2) | 27-23 | |
| » Starters: Milt Pappas vs Ned Garver | Third | 1½ out |
| Saturday, June 6 |
| » Lost to Athletics (24-23), 5-1 | Municipal Stadium (2-3) | 27-24 | |
| » Starters: Hal Brown vs Bud Daley | Third | 1½ out |
| Sunday, June 7 |
| » Defeated Athletics (24-24), 3-0 | Municipal Stadium (3-3) | 28-24 | |
| » Starters: Hoyt Wilhelm vs Ray Herbert | Second | 1 out |
| Tuesday, June 9 |
| » Defeated Indians (26-24), 7-3 | Memorial Stadium (14-12) | 29-24 | Won 2 |
| » Starters: Mudcat Grant vs Billy O'Dell | First | -- |
| Wednesday, June 10 |
| » Lost to Indians (27-24), 11-8 | Memorial Stadium (14-13) | 29-25 | |
| » Starters: Gary Bell vs Jerry Walker | Second | 1 out |
| Thursday, June 11 |
| » Lost to Indians (28-24), 2-1 | Memorial Stadium (14-14) | 29-26 | Lost 2 |
| » Starters: Don Ferrarese vs Milt Pappas | Third | 2 out |
| Saturday, June 13 |
| » Defeated White Sox (31-25), 6-4 | Memorial Stadium (15-14) | 30-26 | |
| » Starters: Bob Shaw vs Hal Brown | Third | 1 out |
| Sunday, June 14 |
| » Lost to White Sox (32-25), 9-6 | Memorial Stadium (15-15) | 30-27 | |
| » Starters: Early Wynn vs Jack Harshman | Fourth | 3 out |
| » Lost to White Sox (33-25), 3-2 | Memorial Stadium (15-16) | 30-28 | Lost 2 |
| » Starters: Dick Donovan vs Billy O'Dell | Fourth | 3 out |
| Monday, June 15 |
| » Lost to Tigers (32-27), 6-4 | Memorial Stadium (15-17) | 30-29 | Lost 3 |
| » Starters: Ray Narleski vs Hoyt Wilhelm | Fourth | 3½ out |
| Wednesday, June 17 |
| » Defeated Tigers (32-28), 4-0 | Memorial Stadium (16-17) | 31-29 | |
| » Starters: Jim Bunning vs Milt Pappas | Fourth | 3½ out |
| Thursday, June 18 |
| » Defeated Tigers (32-29), 7-6 | Memorial Stadium (17-17) | 32-29 | Won 2 |
| » Starters: Don Mossi vs Jerry Walker | Third | 2½ out |
| Friday, June 19 |
| » Defeated Athletics (26-32), 8-2 | Memorial Stadium (18-17) | 33-29 | Won 3 |
| » Starters: Johnny Kucks vs Billy O'Dell | Third | 2 out |
| » Defeated Athletics (26-33), 2-0 | Memorial Stadium (19-17) | 34-29 | Won 4 |
| » Starters: Rip Coleman vs Hal Brown | Third | 2 out |
| Saturday, June 20 |
| » Lost to Athletics (27-33), 6-2 | Memorial Stadium (19-18) | 34-30 | |
| » Starters: Bud Daley vs Hoyt Wilhelm | Third | 2 out |
| Sunday, June 21 |
| » Lost to Athletics (28-33), 7-0 | Memorial Stadium (19-19) | 34-31 | Lost 2 |
| » Starters: Ned Garver vs Arnie Portocarrero | Third | 2½ out |
| Monday, June 22 |
| » Major-league debuts: Eddie Fisher (Giants) |
| Tuesday, June 23 |
| » Defeated Indians (35-28), 5-1 | Cleveland Stadium (2-1) | 35-31 | |
| » Starters: Milt Pappas vs Gary Bell | Third | 1½ out |
| Wednesday, June 24 |
| » Defeated Indians (35-29), 7-4 | Cleveland Stadium (3-1) | 36-31 | Won 2 |
| » Starters: Hal Brown vs Herb Score | Second | 1½ out |
| Thursday, June 25 |
| » Lost to Indians (36-29), 3-2 | Cleveland Stadium (3-2) | 36-32 | |
| » Starters: Hoyt Wilhelm vs Bobby Locke | Third | 1½ out |
| Friday, June 26 |
| » Defeated Tigers (35-34), 12-7 | Tiger Stadium (1-1) | 37-32 | |
| » Starters: Billy O'Dell vs Ray Narleski | Second | 2 out |
| » Defeated Tigers (35-35), 4-1 | Tiger Stadium (2-1) | 38-32 | Won 2 |
| » Starters: Jerry Walker vs Frank Lary | Second | 2 out |
| Saturday, June 27 |
| » Lost to Tigers (36-35), 12-2 | Tiger Stadium (2-2) | 38-33 | |
| » Starters: Billy Hoeft vs Paul Foytack | Third | 2 out |
| Sunday, June 28 |
| » Lost to Tigers (37-35), 7-2 | Tiger Stadium (2-3) | 38-34 | Lost 2 |
| » Starters: Milt Pappas vs Don Mossi | Third | 2½ out |
| Tuesday, June 30 |
| » Lost to Yankees (37-35), 4-1 | Memorial Stadium (19-20) | 38-35 | Lost 3 |
| » Starters: Duke Maas vs Hoyt Wilhelm | Third | 3½ out |
| Wednesday, July 1 |
| » Lost to Yankees (38-35), 4-0 | Memorial Stadium (19-21) | 38-36 | Lost 4 |
| » Starters: Ralph Terry vs Hal Brown | Fifth | 3½ out |
| Thursday, July 2 |
| » Defeated Yankees (38-36), 3-1 | Memorial Stadium (20-21) | 39-36 | |
| » Starters: Don Larsen vs Jerry Walker | Fourth | 2½ out |
| Friday, July 3 |
| » Defeated Red Sox (31-43), 6-1 | Memorial Stadium (21-21) | 40-36 | Won 2 |
| » Starters: Jack Harshman vs Jack Fisher | Third | 2½ out |
| Saturday, July 4 |
| » Defeated Red Sox (31-44), 11-5 | Memorial Stadium (22-21) | 41-36 | Won 3 |
| » Starters: Ted Wills vs Milt Pappas | Third | 3 out |
| Sunday, July 5 |
| » Lost to Red Sox (32-44), 9-0 | Memorial Stadium (22-22) | 41-37 | |
| » Starters: Tom Brewer vs Hal Brown | Third | 4½ out |
| » Lost to Red Sox (33-44), 6-3 | Memorial Stadium (22-23) | 41-38 | Lost 2 |
| » Starters: Frank Baumann vs Hoyt Wilhelm | Third | 4½ out |
| Thursday, July 9 |
| » Defeated Senators (37-42), 8-0 | Griffith Stadium (3-1) | 42-38 | |
| » Starters: Milt Pappas vs Russ Kemmerer | Third | 3 out |
| » Defeated Senators (37-43), 5-0 | Griffith Stadium (4-1) | 43-38 | Won 2 |
| » Starters: Jerry Walker vs Pedro Ramos | Third | 3 out |
| Friday, July 10 |
| » Lost to Senators (38-43), 7-6 | Griffith Stadium (4-2) | 43-39 | |
| » Starters: Jack Fisher vs Camilo Pascual | Third | 4 out |
| Saturday, July 11 |
| » Lost to Senators (39-43), 9-3 | Griffith Stadium (4-3) | 43-40 | Lost 2 |
| » Starters: Hal Brown vs Bill Fischer | Third | 5 out |
| Sunday, July 12 |
| » Defeated Senators (39-44), 5-1 | Griffith Stadium (5-3) | 44-40 | |
| » Starters: Hoyt Wilhelm vs Russ Kemmerer | Third | 4½ out |
| Monday, July 13 |
| Future Oriole Mark Brown is born in Bellows Falls, VT. |
| Tuesday, July 14 |
| » Lost to Athletics (36-47), 1-0 | Memorial Stadium (22-24) | 44-41 | |
| » Starters: Ray Herbert vs Billy O'Dell | Third | 4 out |
| » Defeated Athletics (36-48), 3-1 | Memorial Stadium (23-24) | 45-41 | |
| » Starters: Johnny Kucks vs Milt Pappas | Third | 4 out |
| Thursday, July 16 |
| » Lost to Athletics (37-48), 4-3 | Memorial Stadium (23-25) | 45-42 | |
| » Starters: Bud Daley vs Jerry Walker | Third | 4½ out |
| Friday, July 17 |
| » Defeated Tigers (42-48), 3-2 | Memorial Stadium (24-25) | 46-42 | |
| » Starters: Don Mossi vs Hal Brown | Third | 4½ out |
| Saturday, July 18 |
| » Defeated Tigers (42-49), 5-2 | Memorial Stadium (25-25) | 47-42 | Won 2 |
| » Starters: Paul Foytack vs Arnie Portocarrero | Third | 5 out |
| » Lost to Tigers (43-49), 2-0 | Memorial Stadium (25-26) | 47-43 | |
| » Starters: Frank Lary vs Hoyt Wilhelm | Third | 5 out |
| Sunday, July 19 |
| » Defeated Tigers (43-50), 2-1 | Memorial Stadium (26-26) | 48-43 | |
| » Starters: Jim Bunning vs Billy O'Dell | Third | 3½ out |
| Tuesday, July 21 |
| » Lost to Athletics (41-49), 8-1 | Municipal Stadium (3-4) | 48-44 | |
| » Starters: Milt Pappas vs Bud Daley | Third | 4½ out |
| Future Oriole Mark Williamson is born in Corpus Christi, TX. |
| Wednesday, July 22 |
| » Lost to Athletics (42-49), 6-3 | Municipal Stadium (3-5) | 48-45 | Lost 2 |
| » Starters: Jerry Walker vs Ray Herbert | Third | 5½ out |
| Thursday, July 23 |
| » Lost to Athletics (43-49), 9-3 | Municipal Stadium (3-6) | 48-46 | Lost 3 |
| » Starters: Hal Brown vs Ned Garver | Third | 6 out |
| Friday, July 24 |
| » Lost to White Sox (54-39), 2-1 | Comiskey Park I (2-3) | 48-47 | Lost 4 |
| » Starters: Hoyt Wilhelm vs Billy Pierce | Third | 7 out |
| Saturday, July 25 |
| » Lost to White Sox (55-39), 3-2 | Comiskey Park I (2-4) | 48-48 | Lost 5 |
| » Starters: Billy O'Dell vs Bob Shaw | Third | 8 out |
| Sunday, July 26 |
| » Lost to White Sox (56-39), 4-1 | Comiskey Park I (2-5) | 48-49 | Lost 6 |
| » Starters: Arnie Portocarrero vs Early Wynn | Third | 8½ out |
| » Defeated White Sox (56-40), 4-0 | Comiskey Park I (3-5) | 49-49 | |
| » Starters: Milt Pappas vs Barry Latman | Third | 8½ out |
| Monday, July 27 |
| » Defeated Tigers (48-52), 5-2 | Tiger Stadium (3-3) | 50-49 | Won 2 |
| » Starters: Hal Brown vs Jim Bunning | Second | 7½ out |
| » Major-league debuts: Barry Shetrone (Orioles) |
| Tuesday, July 28 |
| » Lost to Tigers (49-52), 8-3 | Tiger Stadium (3-4) | 50-50 | |
| » Starters: Hoyt Wilhelm vs Don Mossi | Third | 8½ out |
| Wednesday, July 29 |
| » Defeated Tigers (49-53), 5-1 | Tiger Stadium (4-4) | 51-50 | |
| » Starters: Jerry Walker vs Paul Foytack | Third | 8 out |
| » Major-league debuts: Steve Demeter (Tigers) |
| Thursday, July 30 |
| » Lost to Tigers (50-53), 11-2 | Tiger Stadium (4-5) | 51-51 | |
| » Starters: Billy O'Dell vs Frank Lary | Fourth | 9 out |
| Friday, July 31 |
| » Lost to Indians (59-42), 5-4 | Cleveland Stadium (3-3) | 51-52 | Lost 2 |
| » Starters: Arnie Portocarrero vs Jim Perry | Fourth | 10 out |
| Saturday, August 1 |
| » Defeated Indians (59-43), 5-2 | Cleveland Stadium (4-3) | 52-52 | |
| » Starters: Hal Brown vs Bobby Locke | Fourth | 10 out |
| Sunday, August 2 |
| » Defeated Indians (59-44), 5-4 | Cleveland Stadium (5-3) | 53-52 | Won 2 |
| » Starters: Hoyt Wilhelm vs Cal McLish | Fourth | 11 out |
| » Lost to Indians (60-44), 6-3 | Cleveland Stadium (5-4) | 53-53 | |
| » Starters: Milt Pappas vs Gary Bell | Fourth | 11 out |
| Tuesday, August 4 |
| » Defeated White Sox (62-41), 3-2 | Memorial Stadium (27-26) | 54-53 | |
| » Starters: Ken McBride vs Billy Hoeft | Third | 10 out |
| » Major-league debuts: Ken McBride (White Sox) |
| Wednesday, August 5 |
| » Lost to White Sox (63-41), 2-0 | Memorial Stadium (27-27) | 54-54 | |
| » Starters: Barry Latman vs Jack Fisher | Third | 10 out |
| » Defeated White Sox (63-42), 7-1 | Memorial Stadium (28-27) | 55-54 | |
| » Starters: Early Wynn vs Arnie Portocarrero | Third | 10 out |
| Thursday, August 6 |
| » Tied White Sox, 1-1 | Memorial Stadium (28-27) | 55-54 | |
| » Starters: Billy Pierce vs Billy O'Dell | Third | 10 out |
| Friday, August 7 |
| » Lost to Indians (64-45), 8-5 | Memorial Stadium (28-28) | 55-55 | |
| » Starters: Herb Score vs Jerry Walker | Third | 11 out |
| Sunday, August 9 |
| » Defeated Indians (64-46), 4-3 | Memorial Stadium (29-28) | 56-55 | |
| » Starters: Jim Perry vs Milt Pappas | Third | 11½ out |
| Wednesday, August 12 |
| » Lost to Red Sox (51-62), 5-4 | Memorial Stadium (29-29) | 56-56 | |
| » Starters: Bill Monbouquette vs Billy Hoeft | Fourth | 12 out |
| Thursday, August 13 |
| Future Oriole Tom Niedenfuer is born in St. Louis Park, MN. |
| Friday, August 14 |
| » Lost to Senators (47-68), 7-3 | Memorial Stadium (29-30) | 56-57 | Lost 2 |
| » Starters: Bill Fischer vs Hal Brown | Fourth | 13½ out |
| Saturday, August 15 |
| » Defeated Senators (47-69), 4-2 | Memorial Stadium (30-30) | 57-57 | |
| » Starters: Chuck Stobbs vs Milt Pappas | Third | 12½ out |
| Sunday, August 16 |
| » Lost to Senators (48-69), 6-1 | Memorial Stadium (30-31) | 57-58 | |
| » Starters: Pedro Ramos vs Jerry Walker | Third | 12½ out |
| Tuesday, August 18 |
| » Lost to White Sox (70-45), 6-4 | Comiskey Park I (3-6) | 57-59 | Lost 2 |
| » Starters: Arnie Portocarrero vs Early Wynn | Fourth | 13½ out |
| Wednesday, August 19 |
| » Defeated White Sox (70-46), 3-1 | Comiskey Park I (4-6) | 58-59 | |
| » Starters: Billy O'Dell vs Bob Shaw | Fourth | 12½ out |
| Thursday, August 20 |
| » Defeated White Sox (70-47), 7-6 | Comiskey Park I (5-6) | 59-59 | Won 2 |
| » Starters: Hoyt Wilhelm vs Barry Latman | Third | 11½ out |
| Friday, August 21 |
| » Lost to Indians (70-51), 5-0 | Cleveland Stadium (5-5) | 59-60 | |
| » Starters: Hal Brown vs Jack Harshman | Fourth | 12½ out |
| Saturday, August 22 |
| » Lost to Indians (71-51), 4-2 | Cleveland Stadium (5-6) | 59-61 | Lost 2 |
| » Starters: Milt Pappas vs Gary Bell | Fourth | 13½ out |
| Sunday, August 23 |
| » Lost to Tigers (61-63), 9-5 | Tiger Stadium (4-6) | 59-62 | Lost 3 |
| » Starters: Arnie Portocarrero vs Frank Lary | Fifth | 14 out |
| Monday, August 24 |
| » Defeated Tigers (61-64), 11-0 | Tiger Stadium (5-6) | 60-62 | |
| » Starters: Hoyt Wilhelm vs Don Mossi | Fourth | 14 out |
| Tuesday, August 25 |
| » Lost to Athletics (59-66), 6-5 | Municipal Stadium (3-7) | 60-63 | |
| » Starters: Billy O'Dell vs Ray Herbert | Fourth | 15 out |
| Wednesday, August 26 |
| » Defeated Athletics (59-67), 6-3 | Municipal Stadium (4-7) | 61-63 | |
| » Starters: Jerry Walker vs Bud Daley | Third | 14 out |
| Friday, August 28 |
| » Lost to Red Sox (59-69), 6-4 | Fenway Park (3-4) | 61-64 | |
| » Starters: Hal Brown vs Tom Brewer | Fourth | 15½ out |
| Saturday, August 29 |
| » Lost to Red Sox (60-69), 4-1 | Fenway Park (3-5) | 61-65 | Lost 2 |
| » Starters: Milt Pappas vs Jerry Casale | Fourth | 16½ out |
| Sunday, August 30 |
| » Lost to Red Sox (61-69), 3-0 | Fenway Park (3-6) | 61-66 | Lost 3 |
| » Starters: Hoyt Wilhelm vs Frank Sullivan | Fifth | 18 out |
| Tuesday, September 1 |
| » Lost to Yankees (65-66), 5-0 | Memorial Stadium (30-32) | 61-67 | Lost 4 |
| » Starters: Whitey Ford vs Jerry Walker | Fifth | 18 out |
| Wednesday, September 2 |
| » Defeated Red Sox (62-71), 4-0 | Memorial Stadium (31-32) | 62-67 | |
| » Starters: Tom Brewer vs Billy O'Dell | Fifth | 18½ out |
| Future Oriole Drungo Hazewood is born in Mobile, AL. |
| Thursday, September 3 |
| » Defeated Red Sox (62-72), 5-4 | Memorial Stadium (32-32) | 63-67 | Won 2 |
| » Starters: Frank Baumann vs Hal Brown | Fifth | 18 out |
| Friday, September 4 |
| » Defeated Yankees (67-67), 3-0 | Yankee Stadium (5-1) | 64-67 | Won 3 |
| » Starters: Milt Pappas vs Ralph Terry | Fourth | 18 out |
| Saturday, September 5 |
| » Lost to Yankees (68-67), 3-2 | Yankee Stadium (5-2) | 64-68 | |
| » Starters: Hoyt Wilhelm vs Jim Coates | Fourth | 18 out |
| Sunday, September 6 |
| » Defeated Yankees (68-68), 5-4 | Yankee Stadium (6-2) | 65-68 | |
| » Starters: Jerry Walker vs Whitey Ford | Fifth | 17 out |
| Monday, September 7 |
| » Defeated Senators (55-82), 7-0 | Memorial Stadium (33-32) | 66-68 | Won 2 |
| » Starters: Russ Kemmerer vs Billy O'Dell | Fifth | 18 out |
| » Lost to Senators (56-82), 8-1 | Memorial Stadium (33-33) | 66-69 | |
| » Starters: Bill Fischer vs Jack Fisher | Fifth | 18 out |
| » Major-league debuts: Fred Valentine (Orioles) |
| Wednesday, September 9 |
| » Lost to Indians (81-56), 3-2 | Memorial Stadium (33-34) | 66-70 | Lost 2 |
| » Starters: Jack Harshman vs Milt Pappas | Fifth | 20 out |
| » Lost to Indians (82-56), 4-1 | Memorial Stadium (33-35) | 66-71 | Lost 3 |
| » Starters: Jim Perry vs Hal Brown | Fifth | 20 out |
| Thursday, September 10 |
| » Defeated Indians (82-57), 6-1 | Memorial Stadium (34-35) | 67-71 | |
| » Starters: Cal McLish vs Hoyt Wilhelm | Fifth | 19 out |
| Friday, September 11 |
| » Defeated White Sox (87-54), 3-0 | Memorial Stadium (35-35) | 68-71 | Won 2 |
| » Starters: Billy Pierce vs Jack Fisher | Fifth | 17 out |
| » Defeated White Sox (87-55), 1-0 | Memorial Stadium (36-35) | 69-71 | Won 3 |
| » Starters: Barry Latman vs Jerry Walker | Fifth | 17 out |
| Saturday, September 12 |
| » Lost to White Sox (88-55), 6-1 | Memorial Stadium (36-36) | 69-72 | |
| » Starters: Early Wynn vs Billy O'Dell | Fifth | 18 out |
| » Major-league debuts: Bob Saverine (Orioles) |
| Sunday, September 13 |
| » Lost to Athletics (61-80), 9-5 | Memorial Stadium (36-37) | 69-73 | Lost 2 |
| » Starters: Ned Garver vs Arnie Portocarrero | Fifth | 19½ out |
| » Lost to Athletics (62-80), 4-1 | Memorial Stadium (36-38) | 69-74 | Lost 3 |
| » Starters: Bud Daley vs Milt Pappas | Fifth | 19½ out |
| Monday, September 14 |
| » Defeated Athletics (62-81), 9-4 | Memorial Stadium (37-38) | 70-74 | |
| » Starters: Al Grunwald vs Hal Brown | Fifth | 18½ out |
| Tuesday, September 15 |
| » Defeated Tigers (71-74), 2-1 | Memorial Stadium (38-38) | 71-74 | Won 2 |
| » Starters: Paul Foytack vs Hoyt Wilhelm | Fourth | 18½ out |
| Wednesday, September 16 |
| » Lost to Tigers (72-74), 3-1 | Memorial Stadium (38-39) | 71-75 | |
| » Starters: Don Mossi vs Jack Fisher | Fifth | 18½ out |
| Friday, September 18 |
| » Lost to Senators (62-85), 5-3 | Griffith Stadium (5-4) | 71-76 | Lost 2 |
| » Starters: Jerry Walker vs Bill Fischer | Fifth | 19½ out |
| Saturday, September 19 |
| » Defeated Senators (62-86), 5-3 | Griffith Stadium (6-4) | 72-76 | |
| » Starters: Milt Pappas vs Tex Clevenger | Fifth | 18½ out |
| Sunday, September 20 |
| » Lost to Senators (63-86), 5-0 | Griffith Stadium (6-5) | 72-77 | |
| » Starters: Billy O'Dell vs Camilo Pascual | Fifth | 18½ out |
| Tuesday, September 22 |
| » Lost to Red Sox (71-79), 4-3 | Fenway Park (3-7) | 72-78 | Lost 2 |
| » Starters: Hoyt Wilhelm vs Frank Sullivan | Fifth | 19½ out |
| Future Oriole John Stefero is born in Sumter, SC. |
| Wednesday, September 23 |
| » Lost to Red Sox (72-79), 4-0 | Fenway Park (3-8) | 72-79 | Lost 3 |
| » Starters: Jack Fisher vs Jerry Casale | Fifth | 20 out |
| Friday, September 25 |
| » Lost to Yankees (79-73), 5-2 | Yankee Stadium (6-3) | 72-80 | Lost 4 |
| » Starters: Jerry Walker vs Whitey Ford | Sixth | 20 out |
| Saturday, September 26 |
| » Defeated Yankees (79-74), 7-2 | Yankee Stadium (7-3) | 73-80 | |
| » Starters: Milt Pappas vs Mark Freeman | Sixth | 20 out |
| Sunday, September 27 |
| » Defeated Yankees (79-75), 3-1 | Yankee Stadium (8-3) | 74-80 | Won 2 |
| » Starters: Billy O'Dell vs Gabe Gabler | Sixth | 20 out |
| Tuesday, October 6 |
| Future Oriole Greg Walker is born in Douglas, GA. |
| Thursday, October 8 |
| Future Oriole Mike Morgan is born in Tulare, CA. |
| Saturday, October 24 |
| Future Oriole Dave Johnson is born in Baltimore, MD. |
| Friday, November 6 |
| Future Oriole Leo Hernandez is born in Santa Lucia, Venezuela. |
| Tuesday, November 17 |
| Future Oriole Brad Havens is born in Highland Park, MI. |
| Sunday, November 29 |
| Future Oriole Brian Holton is born in McKeesport, PA. |
| Sunday, December 6 |
| Future Oriole Larry Sheets is born in Staunton, VA. |
Game information provided by Retrosheet (www.retrosheet.org) |
