| Wednesday, January 14 |
| Former Giant John Ganzel dies in Orlando, FL at the age of 85. |
| Wednesday, January 21 |
| Future Giant Ricky Adams is born in Upland, CA. Future Giant Jose Uribe is born in San Cristobal, D.R. Former Giant Hooks Wiltse dies in Long Beach, NY at the age of 79. |
| Saturday, February 14 |
| Future Giant Alejandro Sanchez is born in San Pedro de Macoris, D.R. |
| Wednesday, March 11 |
| Future Giant Chuck Hensley is born in Tulare, CA. |
| Sunday, March 29 |
| Former Giant Johnny Allen dies in St.Petersburg, FL at the age of 54. |
| Friday, April 10 |
| » Defeated Cardinals (0-1), 6-5 | Sportsman's Park III (1-0) | 1-0 | |
| » Starters: Johnny Antonelli vs Larry Jackson | First | -- |
| » Major-league debuts: Gary Blaylock (Cardinals) |
| Saturday, April 11 |
| » Defeated Cardinals (0-2), 5-2 | Sportsman's Park III (2-0) | 2-0 | Won 2 |
| » Starters: Sam Jones vs Ernie Broglio | First | -- |
| » Major-league debuts: Ernie Broglio and Howie Nunn (Cardinals) |
| Sunday, April 12 |
| » Defeated Cardinals (0-3), 6-3 | Sportsman's Park III (3-0) | 3-0 | Won 3 |
| » Starters: Mike McCormick vs Vinegar Bend Mizell | First | -- |
| Tuesday, April 14 |
| » Lost to Cubs (2-1), 5-2 | Seals Stadium (0-1) | 3-1 | |
| » Starters: Dave Hillman vs Jack Sanford | Second | ½ out |
| Wednesday, April 15 |
| » Defeated Cubs (2-2), 7-1 | Seals Stadium (1-1) | 4-1 | |
| » Starters: Moe Drabowsky vs Johnny Antonelli | Second | 1 out |
| » Major-league debuts: Joe Schaffernoth (Cubs) |
| Thursday, April 16 |
| » Lost to Cubs (3-2), 11-3 | Seals Stadium (1-2) | 4-2 | |
| » Starters: Glen Hobbie vs Sam Jones | Third | 1 out |
| Friday, April 17 |
| » Lost to Cardinals (2-5), 4-1 | Seals Stadium (1-3) | 4-3 | Lost 2 |
| » Starters: Vinegar Bend Mizell vs Mike McCormick | Fourth | 1½ out |
| Saturday, April 18 |
| » Defeated Cardinals (2-6), 8-1 | Seals Stadium (2-3) | 5-3 | |
| » Starters: Lindy McDaniel vs Jack Sanford | Second | 1½ out |
| Sunday, April 19 |
| » Defeated Cardinals (2-7), 3-1 | Seals Stadium (3-3) | 6-3 | Won 2 |
| » Starters: Larry Jackson vs Johnny Antonelli | Second | 2 out |
| Monday, April 20 |
| » Lost to Dodgers (6-3), 2-1 | Los Angeles Memorial Coliseum (0-1) | 6-4 | |
| » Starters: Sam Jones vs Don Drysdale | Third | 2½ out |
| Tuesday, April 21 |
| » Lost to Dodgers (7-3), 9-7 | Los Angeles Memorial Coliseum (0-2) | 6-5 | Lost 2 |
| » Starters: Stu Miller vs Stan Williams | Fourth | 2½ out |
| Wednesday, April 22 |
| » Defeated Dodgers (7-4), 6-3 | Los Angeles Memorial Coliseum (1-2) | 7-5 | |
| » Starters: Jack Sanford vs Carl Erskine | Third | 2½ out |
| Friday, April 24 |
| » Defeated Cubs (6-6), 4-3 | Wrigley Field (1-0) | 8-5 | Won 2 |
| » Starters: Johnny Antonelli vs Dave Hillman | Third | 2 out |
| » Major-league debuts: Don Eaddy (Cubs) |
| Saturday, April 25 |
| » Lost to Cubs (7-6), 5-3 | Wrigley Field (1-1) | 8-6 | |
| » Starters: Sam Jones vs Bob Anderson | Third | 2 out |
| Sunday, April 26 |
| » Defeated Cubs (7-7), 3-2 | Wrigley Field (2-1) | 9-6 | |
| » Starters: Jack Sanford vs Glen Hobbie | Third | ½ out |
| Wednesday, April 29 |
| » Lost to Pirates (6-8), 3-2 | Forbes Field (0-1) | 9-7 | |
| » Starters: Johnny Antonelli vs Ron Kline | Fourth | 2 out |
| Friday, May 1 |
| » Defeated Braves (9-5), 6-4 | County Stadium (1-0) | 10-7 | |
| » Starters: Sam Jones vs Carl Willey | Third | 1½ out |
| Saturday, May 2 |
| » Defeated Braves (9-6), 8-5 | County Stadium (2-0) | 11-7 | Won 2 |
| » Starters: Jack Sanford vs Joey Jay | First | -- |
| Sunday, May 3 |
| » Lost to Braves (10-6), 9-4 | County Stadium (2-1) | 11-8 | |
| » Starters: Johnny Antonelli vs Lew Burdette | Second | 1½ out |
| Monday, May 4 |
| » Defeated Reds (11-9), 6-5 | Crosley Field (1-0) | 12-8 | |
| » Starters: Mike McCormick vs Bob Purkey | First | -- |
| Tuesday, May 5 |
| » Lost to Reds (12-9), 5-2 | Crosley Field (1-1) | 12-9 | |
| » Starters: Sam Jones vs Don Newcombe | Second | 1½ out |
| Thursday, May 7 |
| » Lost to Dodgers (14-11), 2-1 | Seals Stadium (3-4) | 12-10 | Lost 2 |
| » Starters: Stan Williams vs Jack Sanford | Fourth | 1½ out |
| Friday, May 8 |
| » Defeated Dodgers (14-12), 9-3 | Seals Stadium (4-4) | 13-10 | |
| » Starters: Danny McDevitt vs Johnny Antonelli | Third | 1½ out |
| » Major-league debuts: Roger McCardell (Giants) |
| Saturday, May 9 |
| » Lost to Dodgers (15-12), 6-5 | Seals Stadium (4-5) | 13-11 | |
| » Starters: Don Drysdale vs Sam Jones | Fourth | 1½ out |
| Sunday, May 10 |
| » Lost to Dodgers (16-12), 3-2 | Seals Stadium (4-6) | 13-12 | Lost 2 |
| » Starters: Johnny Podres vs Mike McCormick | Fourth | 2 out |
| Monday, May 11 |
| » Defeated Pirates (12-15), 14-4 | Seals Stadium (5-6) | 14-12 | |
| » Starters: Bennie Daniels vs Jack Sanford | Fourth | 2 out |
| Tuesday, May 12 |
| » Lost to Pirates (13-15), 6-5 | Seals Stadium (5-7) | 14-13 | |
| » Starters: Vern Law vs Johnny Antonelli | Fourth | 2½ out |
| Future Giant Kevin Bass is born in Redwood City, CA. |
| Wednesday, May 13 |
| » Defeated Phillies (11-17), 6-0 | Seals Stadium (6-7) | 15-13 | |
| » Starters: Ruben Gomez vs Sam Jones | Third | 2 out |
| Thursday, May 14 |
| » Defeated Phillies (11-18), 8-0 | Seals Stadium (7-7) | 16-13 | Won 2 |
| » Starters: Ray Semproch vs Mike McCormick | Third | 2 out |
| Friday, May 15 |
| » Lost to Reds (16-13), 5-2 | Seals Stadium (7-8) | 16-14 | |
| » Starters: Don Newcombe vs Jack Sanford | Fourth | 2½ out |
| Saturday, May 16 |
| » Defeated Reds (16-14), 9-2 | Seals Stadium (8-8) | 17-14 | |
| » Starters: Brooks Lawrence vs Johnny Antonelli | Second | 2½ out |
| Sunday, May 17 |
| » Defeated Reds (16-15), 9-1 | Seals Stadium (9-8) | 18-14 | Won 2 |
| » Starters: Bob Purkey vs Stu Miller | Second | 2½ out |
| Monday, May 18 |
| » Lost to Braves (20-10), 4-2 | Seals Stadium (9-9) | 18-15 | |
| » Starters: Warren Spahn vs Sam Jones | Second | 3½ out |
| Tuesday, May 19 |
| » Lost to Braves (21-10), 8-1 | Seals Stadium (9-10) | 18-16 | Lost 2 |
| » Starters: Joey Jay vs Jack Sanford | Second | 4½ out |
| Wednesday, May 20 |
| » Defeated Braves (21-11), 6-3 | Seals Stadium (10-10) | 19-16 | |
| » Starters: Bob Buhl vs Mike McCormick | Second | 3½ out |
| Friday, May 22 |
| » Lost to Dodgers (21-18), 2-1 | Los Angeles Memorial Coliseum (1-3) | 19-17 | |
| » Starters: Johnny Antonelli vs Don Drysdale | Third | 4½ out |
| Saturday, May 23 |
| » Defeated Dodgers (21-19), 4-2 | Los Angeles Memorial Coliseum (2-3) | 20-17 | |
| » Starters: Sam Jones vs Stan Williams | Second | 3½ out |
| Sunday, May 24 |
| » Defeated Dodgers (21-20), 6-1 | Los Angeles Memorial Coliseum (3-3) | 21-17 | Won 2 |
| » Starters: Jack Sanford vs Danny McDevitt | Second | 3 out |
| Monday, May 25 |
| » Lost to Dodgers (22-20), 8-0 | Seals Stadium (10-11) | 21-18 | |
| » Starters: Johnny Podres vs Mike McCormick | Second | 3 out |
| Former Giant Dave Brain dies in Los Angeles, CA at the age of 81. |
| Tuesday, May 26 |
| » Defeated Dodgers (22-21), 6-4 | Seals Stadium (11-11) | 22-18 | |
| » Starters: Sandy Koufax vs Stu Miller | Second | 3 out |
| Wednesday, May 27 |
| » Defeated Cardinals (18-23), 9-4 | Seals Stadium (12-11) | 23-18 | Won 2 |
| » Starters: Gary Blaylock vs Johnny Antonelli | Second | 3 out |
| Thursday, May 28 |
| » Defeated Cardinals (18-24), 5-4 | Seals Stadium (13-11) | 24-18 | Won 3 |
| » Starters: Larry Jackson vs Sam Jones | Second | 2 out |
| Friday, May 29 |
| » Lost to Cardinals (19-24), 4-2 | Seals Stadium (13-12) | 24-19 | |
| » Starters: Vinegar Bend Mizell vs Jack Sanford | Second | 3 out |
| Saturday, May 30 |
| » Defeated Cubs (23-23), 5-2 | Seals Stadium (14-12) | 25-19 | |
| » Starters: Bob Anderson vs Mike McCormick | Second | 3 out |
| Sunday, May 31 |
| » Defeated Cubs (23-24), 6-3 | Seals Stadium (15-12) | 26-19 | Won 2 |
| » Starters: Glen Hobbie vs Johnny Antonelli | Second | 2½ out |
| Monday, June 1 |
| » Defeated Braves (28-17), 11-2 | County Stadium (3-1) | 27-19 | Won 3 |
| » Starters: Sam Jones vs Joey Jay | Second | 1½ out |
| Tuesday, June 2 |
| » Lost to Braves (29-17), 3-0 | County Stadium (3-2) | 27-20 | |
| » Starters: Stu Miller vs Bob Rush | Second | 2½ out |
| Wednesday, June 3 |
| » Lost to Braves (30-17), 7-4 | County Stadium (3-3) | 27-21 | Lost 2 |
| » Starters: Jack Sanford vs Bob Buhl | Second | 3½ out |
| Thursday, June 4 |
| » Defeated Braves (30-18), 11-5 | County Stadium (4-3) | 28-21 | |
| » Starters: Mike McCormick vs Lew Burdette | Second | 2½ out |
| Friday, June 5 |
| » Lost to Reds (24-26), 7-2 | Crosley Field (1-2) | 28-22 | |
| » Starters: Johnny Antonelli vs Don Newcombe | Second | 2½ out |
| Saturday, June 6 |
| » Defeated Reds (24-27), 13-3 | Crosley Field (2-2) | 29-22 | |
| » Starters: Sam Jones vs Bob Purkey | Second | 1½ out |
| Sunday, June 7 |
| » Defeated Reds (24-28), 5-3 | Crosley Field (3-2) | 30-22 | Won 2 |
| » Starters: Jack Sanford vs Brooks Lawrence | Second | 2 out |
| » Lost to Reds (25-28), 7-1 | Crosley Field (3-3) | 30-23 | |
| » Starters: Mike McCormick vs Orlando Pena | Second | 2 out |
| Monday, June 8 |
| » Lost to Pirates (29-26), 12-9 | Forbes Field (0-2) | 30-24 | Lost 2 |
| » Starters: Stu Miller vs Ron Kline | Second | 3 out |
| Tuesday, June 9 |
| » Defeated Pirates (29-27), 6-2 | Forbes Field (1-2) | 31-24 | |
| » Starters: Johnny Antonelli vs Vern Law | Second | 2 out |
| Wednesday, June 10 |
| » Defeated Pirates (29-28), 11-7 | Forbes Field (2-2) | 32-24 | Won 2 |
| » Starters: Sam Jones vs George Witt | Second | 1 out |
| Thursday, June 11 |
| » Lost to Pirates (30-28), 12-9 | Forbes Field (2-3) | 32-25 | |
| » Starters: Jack Sanford vs Bob Friend | Second | 2 out |
| Friday, June 12 |
| » Defeated Phillies (21-34), 3-0 | Shibe Park (1-0) | 33-25 | |
| » Starters: Mike McCormick vs Jack Meyer | Second | 1 out |
| Saturday, June 13 |
| » Defeated Phillies (21-35), 2-1 | Shibe Park (2-0) | 34-25 | Won 2 |
| » Starters: Johnny Antonelli vs Ray Semproch | Second | 1 out |
| Sunday, June 14 |
| » Lost to Phillies (22-35), 7-5 | Shibe Park (2-1) | 34-26 | |
| » Starters: Sam Jones vs Gene Conley | Second | 1½ out |
| » Lost to Phillies (23-35), 6-3 | Shibe Park (2-2) | 34-27 | Lost 2 |
| » Starters: Joe Shipley vs Robin Roberts | Second | 1½ out |
| Tuesday, June 16 |
| » Lost to Reds (29-32), 2-1 | Seals Stadium (15-13) | 34-28 | Lost 3 |
| » Starters: Don Newcombe vs Mike McCormick | Second | 2 out |
| Wednesday, June 17 |
| » Defeated Reds (29-33), 7-5 | Seals Stadium (16-13) | 35-28 | |
| » Starters: Orlando Pena vs Johnny Antonelli | Second | ½ out |
| Thursday, June 18 |
| » Defeated Reds (29-34), 8-3 | Seals Stadium (17-13) | 36-28 | Won 2 |
| » Starters: Joe Nuxhall vs Al Worthington | Second | ½ out |
| Friday, June 19 |
| » Defeated Braves (36-28), 4-3 | Seals Stadium (18-13) | 37-28 | Won 3 |
| » Starters: Bob Buhl vs Sam Jones | First | -- |
| Saturday, June 20 |
| » Lost to Braves (37-28), 4-1 | Seals Stadium (18-14) | 37-29 | |
| » Starters: Lew Burdette vs Mike McCormick | Second | ½ out |
| Sunday, June 21 |
| » Lost to Braves (38-28), 13-3 | Seals Stadium (18-15) | 37-30 | Lost 2 |
| » Starters: Warren Spahn vs Johnny Antonelli | Second | 1½ out |
| Monday, June 22 |
| » Defeated Pirates (37-33), 4-1 | Seals Stadium (19-15) | 38-30 | |
| » Starters: Ron Kline vs Eddie Fisher | Second | 1 out |
| » Major-league debuts: Eddie Fisher (Giants) |
| Tuesday, June 23 |
| » Lost to Pirates (38-33), 5-1 | Seals Stadium (19-16) | 38-31 | |
| » Starters: Vern Law vs Sam Jones | Second | 2 out |
| Wednesday, June 24 |
| » Defeated Pirates (38-34), 4-3 | Seals Stadium (20-16) | 39-31 | |
| » Starters: Bob Friend vs Johnny Antonelli | Second | 2 out |
| Thursday, June 25 |
| » Lost to Pirates (39-34), 3-1 | Seals Stadium (20-17) | 39-32 | |
| » Starters: Harvey Haddix vs Stu Miller | Second | 2 out |
| Friday, June 26 |
| » Defeated Phillies (25-44), 8-0 | Seals Stadium (21-17) | 40-32 | |
| » Starters: Jim Owens vs Mike McCormick | Second | 2 out |
| Saturday, June 27 |
| » Lost to Phillies (26-44), 7-4 | Seals Stadium (21-18) | 40-33 | |
| » Starters: Gene Conley vs Eddie Fisher | Third | 2 out |
| Sunday, June 28 |
| » Defeated Phillies (26-45), 6-0 | Seals Stadium (22-18) | 41-33 | |
| » Starters: Ray Semproch vs Johnny Antonelli | Third | 2 out |
| Monday, June 29 |
| » Defeated Dodgers (43-34), 6-4 | Los Angeles Memorial Coliseum (4-3) | 42-33 | Won 2 |
| » Starters: Jack Sanford vs Roger Craig | Second | 1½ out |
| Tuesday, June 30 |
| » Defeated Dodgers (43-35), 2-0 | Los Angeles Memorial Coliseum (5-3) | 43-33 | Won 3 |
| » Starters: Sam Jones vs Don Drysdale | Second | 1½ out |
| Thursday, July 2 |
| » Lost to Cubs (38-37), 10-4 | Wrigley Field (2-2) | 43-34 | |
| » Starters: Eddie Fisher vs Glen Hobbie | Second | 1½ out |
| Friday, July 3 |
| » Defeated Cubs (38-38), 4-0 | Wrigley Field (3-2) | 44-34 | |
| » Starters: Johnny Antonelli vs Dave Hillman | Second | 1½ out |
| Saturday, July 4 |
| » Defeated Cardinals (36-41), 10-3 | Sportsman's Park III (4-0) | 45-34 | Won 2 |
| » Starters: Mike McCormick vs Larry Jackson | First | -- |
| Sunday, July 5 |
| » Lost to Cardinals (37-41), 4-2 | Sportsman's Park III (4-1) | 45-35 | |
| » Starters: Jack Sanford vs Ernie Broglio | Second | 2 out |
| » Defeated Cardinals (37-42), 4-2 | Sportsman's Park III (5-1) | 46-35 | |
| » Starters: Sam Jones vs Gary Blaylock | Second | 2 out |
| Thursday, July 9 |
| » Defeated Reds (35-46), 3-2 | Crosley Field (4-3) | 47-35 | Won 2 |
| » Starters: Mike McCormick vs Don Newcombe | First | -- |
| Friday, July 10 |
| » Defeated Reds (35-47), 8-6 | Crosley Field (5-3) | 48-35 | Won 3 |
| » Starters: Stu Miller vs Jim O'Toole | First | -- |
| Saturday, July 11 |
| » Defeated Reds (35-48), 5-3 | Crosley Field (6-3) | 49-35 | Won 4 |
| » Starters: Johnny Antonelli vs Jim Brosnan | First | -- |
| Sunday, July 12 |
| » Lost to Braves (45-35), 4-2 | County Stadium (4-4) | 49-36 | |
| » Starters: Jack Sanford vs Lew Burdette | First | -- |
| Monday, July 13 |
| » Lost to Braves (46-35), 3-0 | County Stadium (4-5) | 49-37 | Lost 2 |
| » Starters: Sam Jones vs Warren Spahn | First | -- |
| Thursday, July 16 |
| » Lost to Phillies (32-53), 6-4 | Shibe Park (2-3) | 49-38 | Lost 3 |
| » Starters: Mike McCormick vs Robin Roberts | First | -- |
| » Defeated Phillies (32-54), 1-0 | Shibe Park (3-3) | 50-38 | |
| » Starters: Johnny Antonelli vs Gene Conley | First | -- |
| Friday, July 17 |
| » Defeated Pirates (48-43), 4-1 | Forbes Field (3-3) | 51-38 | Won 2 |
| » Starters: Sam Jones vs Ron Kline | First | -- |
| Saturday, July 18 |
| » Defeated Pirates (48-44), 4-3 | Forbes Field (4-3) | 52-38 | Won 3 |
| » Starters: Eddie Fisher vs Harvey Haddix | First | -- |
| Sunday, July 19 |
| » Lost to Pirates (49-44), 3-2 | Forbes Field (4-4) | 52-39 | |
| » Starters: Stu Miller vs Vern Law | First | -- |
| Monday, July 20 |
| » Lost to Dodgers (52-43), 3-2 | Seals Stadium (22-19) | 52-40 | Lost 2 |
| » Starters: Don Drysdale vs Johnny Antonelli | First | -- |
| Former Giant Morrie Arnovich dies in Superior, WI at the age of 49. |
| Tuesday, July 21 |
| » Lost to Dodgers (53-43), 1-0 | Seals Stadium (22-20) | 52-41 | Lost 3 |
| » Starters: Roger Craig vs Sam Jones | First | -- |
| Wednesday, July 22 |
| » Defeated Cardinals (46-48), 6-1 | Seals Stadium (23-20) | 53-41 | |
| » Starters: Dick Ricketts vs Mike McCormick | First | -- |
| Thursday, July 23 |
| » Defeated Cardinals (46-49), 5-1 | Seals Stadium (24-20) | 54-41 | Won 2 |
| » Starters: Vinegar Bend Mizell vs Jack Sanford | First | -- |
| Friday, July 24 |
| » Defeated Cubs (47-48), 6-5 | Seals Stadium (25-20) | 55-41 | Won 3 |
| » Starters: Dave Hillman vs Johnny Antonelli | First | -- |
| Saturday, July 25 |
| » Lost to Cubs (48-48), 5-3 | Seals Stadium (25-21) | 55-42 | |
| » Starters: Art Ceccarelli vs Stu Miller | First | -- |
| Sunday, July 26 |
| » Lost to Cubs (49-48), 7-3 | Seals Stadium (25-22) | 55-43 | Lost 2 |
| » Starters: Bob Anderson vs Mike McCormick | First | -- |
| Tuesday, July 28 |
| » Lost to Phillies (41-56), 3-2 | Seals Stadium (25-23) | 55-44 | Lost 3 |
| » Starters: Jim Owens vs Sam Jones | First | -- |
| Wednesday, July 29 |
| » Lost to Phillies (42-56), 3-1 | Seals Stadium (25-24) | 55-45 | Lost 4 |
| » Starters: Don Cardwell vs Johnny Antonelli | Second | 1½ out |
| Future Giant Dave LaPoint is born in Glens Falls, NY. Former Giant Boileryard Clarke dies in Princeton, NJ at the age of 91. |
| Thursday, July 30 |
| » Defeated Phillies (42-57), 7-2 | Seals Stadium (26-24) | 56-45 | |
| » Starters: Robin Roberts vs Mike McCormick | First | -- |
| Friday, July 31 |
| » Defeated Pirates (50-54), 4-3 | Seals Stadium (27-24) | 57-45 | Won 2 |
| » Starters: Harvey Haddix vs Jack Sanford | First | -- |
| Saturday, August 1 |
| » Defeated Pirates (50-55), 9-5 | Seals Stadium (28-24) | 58-45 | Won 3 |
| » Starters: George Witt vs Sam Jones | First | -- |
| Sunday, August 2 |
| » Defeated Pirates (50-56), 5-3 | Seals Stadium (29-24) | 59-45 | Won 4 |
| » Starters: Ron Kline vs Johnny Antonelli | First | -- |
| Monday, August 3 |
| Future Giant Jim Gott is born in Hollywood, CA. Future Giant Mike Jeffcoat is born in Pine Bluff, AR. |
| Tuesday, August 4 |
| » Lost to Braves (58-45), 6-1 | Seals Stadium (29-25) | 59-46 | |
| » Starters: Warren Spahn vs Mike McCormick | Second | 1 out |
| » Major-league debuts: Jose Pagan (Giants) |
| Wednesday, August 5 |
| » Defeated Braves (58-46), 4-1 | Seals Stadium (30-25) | 60-46 | |
| » Starters: Bob Buhl vs Jack Sanford | First | -- |
| Thursday, August 6 |
| » Defeated Braves (58-47), 7-1 | Seals Stadium (31-25) | 61-46 | Won 2 |
| » Starters: Lew Burdette vs Sam Jones | First | -- |
| Friday, August 7 |
| » Defeated Reds (50-57), 3-2 | Seals Stadium (32-25) | 62-46 | Won 3 |
| » Starters: Jim O'Toole vs Johnny Antonelli | First | -- |
| Saturday, August 8 |
| » Lost to Reds (51-57), 9-6 | Seals Stadium (32-26) | 62-47 | |
| » Starters: Jay Hook vs Mike McCormick | First | -- |
| Sunday, August 9 |
| » Defeated Reds (51-58), 4-3 | Seals Stadium (33-26) | 63-47 | |
| » Starters: Don Newcombe vs Jack Sanford | First | -- |
| Monday, August 10 |
| » Defeated Cardinals (54-61), 3-2 | Sportsman's Park III (6-1) | 64-47 | Won 2 |
| » Starters: Sam Jones vs Larry Jackson | First | -- |
| Tuesday, August 11 |
| » Defeated Cardinals (54-62), 5-4 | Sportsman's Park III (7-1) | 65-47 | Won 3 |
| » Starters: Johnny Antonelli vs Vinegar Bend Mizell | First | -- |
| » Major-league debuts: Bob Duliba (Cardinals) |
| Thursday, August 13 |
| » Lost to Cubs (55-57), 20-9 | Wrigley Field (3-3) | 65-48 | |
| » Starters: Jack Sanford vs Art Ceccarelli | First | -- |
| Friday, August 14 |
| » Lost to Cubs (56-57), 7-5 | Wrigley Field (3-4) | 65-49 | Lost 2 |
| » Starters: Sam Jones vs Glen Hobbie | First | -- |
| Saturday, August 15 |
| » Defeated Cubs (56-58), 6-4 | Wrigley Field (4-4) | 66-49 | |
| » Starters: Jack Sanford vs Moe Drabowsky | First | -- |
| Sunday, August 16 |
| » Lost to Cubs (57-58), 5-4 | Wrigley Field (4-5) | 66-50 | |
| » Starters: Johnny Antonelli vs Bob Anderson | First | -- |
| Monday, August 17 |
| » Defeated Reds (56-63), 6-3 | Crosley Field (7-3) | 67-50 | |
| » Starters: Mike McCormick vs Jim O'Toole | First | -- |
| Future Giant Brad Wellman is born in Lodi, CA. |
| Tuesday, August 18 |
| » Lost to Reds (57-63), 7-0 | Crosley Field (7-4) | 67-51 | |
| » Starters: Eddie Fisher vs Don Newcombe | First | -- |
| Wednesday, August 19 |
| » Lost to Braves (64-55), 5-2 | County Stadium (4-6) | 67-52 | Lost 2 |
| » Starters: Jack Sanford vs Lew Burdette | First | -- |
| Thursday, August 20 |
| » Defeated Braves (64-56), 5-3 | County Stadium (5-6) | 68-52 | |
| » Starters: Sam Jones vs Warren Spahn | First | -- |
| Friday, August 21 |
| » Defeated Phillies (52-71), 6-0 | Shibe Park (4-3) | 69-52 | Won 2 |
| » Starters: Johnny Antonelli vs Robin Roberts | First | -- |
| » Defeated Phillies (52-72), 10-6 | Shibe Park (5-3) | 70-52 | Won 3 |
| » Starters: Mike McCormick vs Ray Semproch | First | -- |
| Saturday, August 22 |
| » Defeated Phillies (52-73), 8-1 | Shibe Park (6-3) | 71-52 | Won 4 |
| » Starters: Al Worthington vs Jim Owens | First | -- |
| Monday, August 24 |
| » Lost to Pirates (65-61), 6-0 | Forbes Field (4-5) | 71-53 | |
| » Starters: Sam Jones vs Bob Friend | First | -- |
| Tuesday, August 25 |
| » Defeated Pirates (65-62), 12-5 | Forbes Field (5-5) | 72-53 | |
| » Starters: Johnny Antonelli vs Ron Kline | First | -- |
| Wednesday, August 26 |
| » Lost to Pirates (66-62), 5-4 | Forbes Field (5-6) | 72-54 | |
| » Starters: Jack Sanford vs Bennie Daniels | First | -- |
| Thursday, August 27 |
| » Lost to Phillies (53-75), 7-2 | Shibe Park (6-4) | 72-55 | Lost 2 |
| » Starters: Mike McCormick vs Jim Owens | First | -- |
| » Lost to Phillies (54-75), 2-1 | Shibe Park (6-5) | 72-56 | Lost 3 |
| » Starters: Al Worthington vs Don Cardwell | First | -- |
| Former Giant Claude Jonnard dies in Nashville, TN at the age of 62. |
| Friday, August 28 |
| » Defeated Dodgers (70-59), 5-0 | Los Angeles Memorial Coliseum (6-3) | 73-56 | |
| » Starters: Sam Jones vs Don Drysdale | First | -- |
| Sunday, August 30 |
| » Lost to Dodgers (71-59), 7-6 | Los Angeles Memorial Coliseum (6-4) | 73-57 | |
| » Starters: Johnny Antonelli vs Larry Sherry | First | -- |
| Monday, August 31 |
| » Lost to Dodgers (72-59), 5-2 | Los Angeles Memorial Coliseum (6-5) | 73-58 | Lost 2 |
| » Starters: Jack Sanford vs Sandy Koufax | First | -- |
| Wednesday, September 2 |
| » Defeated Cubs (62-68), 4-3 | Seals Stadium (34-26) | 74-58 | |
| » Starters: Art Ceccarelli vs Mike McCormick | First | -- |
| Thursday, September 3 |
| » Defeated Cubs (62-69), 8-5 | Seals Stadium (35-26) | 75-58 | Won 2 |
| » Starters: Bob Anderson vs Johnny Antonelli | First | -- |
| Friday, September 4 |
| » Lost to Cubs (63-69), 2-1 | Seals Stadium (35-27) | 75-59 | |
| » Starters: Glen Hobbie vs Jack Sanford | First | -- |
| Saturday, September 5 |
| » Defeated Cardinals (63-74), 3-2 | Seals Stadium (36-27) | 76-59 | |
| » Starters: Vinegar Bend Mizell vs Johnny Antonelli | First | -- |
| Sunday, September 6 |
| » Lost to Cardinals (64-74), 1-0 | Seals Stadium (36-28) | 76-60 | |
| » Starters: Larry Jackson vs Mike McCormick | First | -- |
| Monday, September 7 |
| » Defeated Cardinals (64-75), 4-2 | Seals Stadium (37-28) | 77-60 | |
| » Starters: Bob Gibson vs Sam Jones | First | -- |
| Wednesday, September 9 |
| » Defeated Pirates (71-69), 7-2 | Seals Stadium (38-28) | 78-60 | Won 2 |
| » Starters: Harvey Haddix vs Jack Sanford | First | -- |
| Thursday, September 10 |
| » Lost to Pirates (72-69), 5-3 | Seals Stadium (38-29) | 78-61 | |
| » Starters: Vern Law vs Johnny Antonelli | First | -- |
| Friday, September 11 |
| » Lost to Phillies (60-82), 1-0 | Seals Stadium (38-30) | 78-62 | Lost 2 |
| » Starters: Robin Roberts vs Mike McCormick | First | -- |
| Saturday, September 12 |
| » Defeated Phillies (60-83), 9-1 | Seals Stadium (39-30) | 79-62 | |
| » Starters: Humberto Robinson vs Sam Jones | First | -- |
| Sunday, September 13 |
| » Defeated Phillies (60-84), 1-0 | Seals Stadium (40-30) | 80-62 | Won 2 |
| » Starters: Don Cardwell vs Jack Sanford | First | -- |
| Monday, September 14 |
| » Lost to Reds (71-74), 4-1 | Seals Stadium (40-31) | 80-63 | |
| » Starters: Jim Brosnan vs Johnny Antonelli | First | -- |
| Tuesday, September 15 |
| » Defeated Reds (71-75), 13-6 | Seals Stadium (41-31) | 81-63 | |
| » Starters: Jay Hook vs Mike McCormick | First | -- |
| Wednesday, September 16 |
| » Lost to Braves (80-65), 2-0 | Seals Stadium (41-32) | 81-64 | |
| » Starters: Lew Burdette vs Sam Jones | First | -- |
| » Major-league debuts: Al Spangler (Braves) |
| Thursday, September 17 |
| » Defeated Braves (80-66), 13-6 | Seals Stadium (42-32) | 82-64 | |
| » Starters: Warren Spahn vs Jack Sanford | First | -- |
| Saturday, September 19 |
| » Lost to Dodgers (81-66), 4-1 | Seals Stadium (42-33) | 82-65 | |
| » Starters: Roger Craig vs Johnny Antonelli | First | -- |
| » Lost to Dodgers (82-66), 5-3 | Seals Stadium (42-34) | 82-66 | Lost 2 |
| » Starters: Don Drysdale vs Mike McCormick | First | -- |
| Sunday, September 20 |
| » Lost to Dodgers (83-66), 8-2 | Seals Stadium (42-35) | 82-67 | Lost 3 |
| » Starters: Johnny Podres vs Sam Jones | Third | 1 out |
| Tuesday, September 22 |
| » Lost to Cubs (72-78), 5-4 | Wrigley Field (4-6) | 82-68 | Lost 4 |
| » Starters: Jack Sanford vs Dave Hillman | Third | 2 out |
| Wednesday, September 23 |
| » Lost to Cubs (73-78), 9-8 | Wrigley Field (4-7) | 82-69 | Lost 5 |
| » Starters: Johnny Antonelli vs Bob Anderson | Second | 2 out |
| Saturday, September 26 |
| » Defeated Cardinals (69-83), 4-0 | Sportsman's Park III (8-1) | 83-69 | |
| » Starters: Sam Jones vs Vinegar Bend Mizell | Second | 1½ out |
| Sunday, September 27 |
| » Lost to Cardinals (70-83), 2-1 | Sportsman's Park III (8-2) | 83-70 | |
| » Starters: Mike McCormick vs Larry Jackson | Second | 3 out |
| » Lost to Cardinals (71-83), 14-8 | Sportsman's Park III (8-3) | 83-71 | Lost 2 |
| » Starters: Marshall Renfroe vs Bob Miller | Second | 3 out |
| » Major-league debuts: Marshall Renfroe (Giants) |
| Saturday, October 10 |
| Future Giant Jim Weaver is born in Kingston, NY. Former Giant Bunny Hearn dies in Wilson, NC at the age of 69. |
| Saturday, November 28 |
| Former Giant Blondy Ryan dies in Swampscott, MA at the age of 54. |
| Monday, November 30 |
| Former Giant Jack Scott dies in Durham, NC at the age of 68. |
| Friday, December 11 |
| Former Giant Doc Marshall dies in Clinton, IL at the age of 85. |
Game information provided by Retrosheet (www.retrosheet.org) |
