| Sunday, January 5 |
| Future White Sox Ron Kittle is born in Gary, IN. |
| Friday, January 24 |
| Future White Sox Neil Allen is born in Kansas City, KS. |
| Thursday, February 6 |
| Future White Sox Bill Dawley is born in Norwich, CT. |
| Monday, February 10 |
| Former White Sox Elmer Jacobs dies in Salem, MO at the age of 66. |
| Sunday, February 23 |
| Future White Sox Juan Agosto is born in Rio Piedras, P.R. |
| Sunday, March 16 |
| Former White Sox Leon Cadore dies in Spokane, WA at the age of 68. |
| Tuesday, March 25 |
| Former White Sox Al Shaw dies in Uhrichsville, OH at the age of 84. |
| Sunday, April 6 |
| Future White Sox Leo Sutherland is born in Santiago De Cuba, Cuba. |
| Monday, April 14 |
| » Major-league debuts: Albie Pearson (Senators) |
| Tuesday, April 15 |
| » Lost to Tigers (1-0), 4-3 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Jim Bunning vs Billy Pierce | Third | 1 out |
| Wednesday, April 16 |
| » Lost to Tigers (2-0), 5-4 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Tom Morgan vs Dick Donovan | Fifth | 2 out |
| Thursday, April 17 |
| » Defeated Tigers (2-1), 4-3 | Comiskey Park I (1-2) | 1-2 | |
| » Starters: Frank Lary vs Early Wynn | Third | 1½ out |
| Friday, April 18 |
| » Defeated Athletics (2-2), 11-7 | Municipal Stadium (1-0) | 2-2 | Won 2 |
| » Starters: Jim Wilson vs Alex Kellner | Third | 1 out |
| Sunday, April 20 |
| » Lost to Athletics (3-2), 8-2 | Municipal Stadium (1-1) | 2-3 | |
| » Starters: Bill Fischer vs Jack Urban | Fourth | 2½ out |
| Monday, April 21 |
| » Lost to Tigers (4-3), 2-1 | Tiger Stadium (0-1) | 2-4 | Lost 2 |
| » Starters: Dick Donovan vs Frank Lary | Seventh | 3½ out |
| Tuesday, April 22 |
| » Lost to Tigers (5-3), 8-2 | Tiger Stadium (0-2) | 2-5 | Lost 3 |
| » Starters: Early Wynn vs Billy Hoeft | Sixth | 4½ out |
| Wednesday, April 23 |
| » Lost to Indians (4-5), 2-0 | Cleveland Stadium (0-1) | 2-6 | Lost 4 |
| » Starters: Billy Pierce vs Herb Score | Seventh | 4½ out |
| Thursday, April 24 |
| » Lost to Indians (5-5), 6-4 | Cleveland Stadium (0-2) | 2-7 | Lost 5 |
| » Starters: Jim Wilson vs Dick Tomanek | Eighth | 5 out |
| Friday, April 25 |
| » Defeated Athletics (6-4), 6-5 | Comiskey Park I (2-2) | 3-7 | |
| » Starters: Alex Kellner vs Early Wynn | Sixth | 4 out |
| Saturday, April 26 |
| » Lost to Athletics (7-4), 7-1 | Comiskey Park I (2-3) | 3-8 | |
| » Starters: Ralph Terry vs Dick Donovan | Seventh | 5 out |
| Wednesday, April 30 |
| » Lost to Orioles (5-6), 3-2 | Memorial Stadium (0-1) | 3-9 | Lost 2 |
| » Starters: Early Wynn vs Jack Harshman | Eighth | 5½ out |
| Thursday, May 1 |
| » Defeated Orioles (5-7), 4-3 | Memorial Stadium (1-1) | 4-9 | |
| » Starters: Jim Wilson vs Connie Johnson | Seventh | 5 out |
| Friday, May 2 |
| » Lost to Senators (8-5), 3-2 | Griffith Stadium (0-1) | 4-10 | |
| » Starters: Dick Donovan vs Camilo Pascual | Eighth | 6 out |
| Tuesday, May 6 |
| » Lost to Red Sox (9-11), 7-5 | Fenway Park (0-1) | 4-11 | Lost 2 |
| » Starters: Billy Pierce vs Mike Fornieles | Eighth | 6½ out |
| Friday, May 9 |
| » Defeated Indians (10-11), 5-0 | Comiskey Park I (3-3) | 5-11 | |
| » Starters: Mudcat Grant vs Early Wynn | Seventh | 6½ out |
| Saturday, May 10 |
| » Defeated Indians (10-12), 5-4 | Comiskey Park I (4-3) | 6-11 | Won 2 |
| » Starters: Don Ferrarese vs Dick Donovan | Seventh | 6½ out |
| Sunday, May 11 |
| » Lost to Indians (11-12), 4-2 | Comiskey Park I (4-4) | 6-12 | |
| » Starters: Ray Narleski vs Billy Pierce | Eighth | 6½ out |
| » Defeated Indians (11-13), 5-2 | Comiskey Park I (5-4) | 7-12 | |
| » Starters: Bob Kelly vs Jim Wilson | Eighth | 6½ out |
| Monday, May 12 |
| » Lost to Athletics (9-10), 2-1 | Municipal Stadium (1-2) | 7-13 | |
| » Starters: Ray Moore vs Alex Kellner | Eighth | 7 out |
| Tuesday, May 13 |
| » Defeated Athletics (9-11), 9-2 | Municipal Stadium (2-2) | 8-13 | |
| » Starters: Early Wynn vs Wally Burnette | Eighth | 7 out |
| Wednesday, May 14 |
| » Defeated Athletics (9-12), 4-1 | Municipal Stadium (3-2) | 9-13 | Won 2 |
| » Starters: Dick Donovan vs Duke Maas | Eighth | 7 out |
| Thursday, May 15 |
| » Lost to Athletics (10-12), 3-0 | Municipal Stadium (3-3) | 9-14 | |
| » Starters: Jim Wilson vs Ned Garver | Seventh | 7½ out |
| Friday, May 16 |
| » Defeated Indians (13-15), 6-3 | Cleveland Stadium (1-2) | 10-14 | |
| » Starters: Billy Pierce vs Don Ferrarese | Seventh | 7½ out |
| Saturday, May 17 |
| » Defeated Indians (13-16), 3-2 | Cleveland Stadium (2-2) | 11-14 | Won 2 |
| » Starters: Ray Moore vs Cal McLish | Fifth | 7½ out |
| Sunday, May 18 |
| » Lost to Indians (14-16), 7-4 | Cleveland Stadium (2-3) | 11-15 | |
| » Starters: Early Wynn vs Mudcat Grant | Eighth | 9½ out |
| » Lost to Indians (15-16), 10-6 | Cleveland Stadium (2-4) | 11-16 | Lost 2 |
| » Starters: Bill Fischer vs Bob Kelly | Eighth | 9½ out |
| Tuesday, May 20 |
| » Lost to Yankees (20-5), 5-1 | Comiskey Park I (5-5) | 11-17 | Lost 3 |
| » Starters: Johnny Kucks vs Dick Donovan | Eighth | 10½ out |
| Wednesday, May 21 |
| » Lost to Yankees (21-5), 5-2 | Comiskey Park I (5-6) | 11-18 | Lost 4 |
| » Starters: Whitey Ford vs Billy Pierce | Seventh | 11½ out |
| Thursday, May 22 |
| » Defeated Orioles (14-14), 5-1 | Comiskey Park I (6-6) | 12-18 | |
| » Starters: Arnie Portocarrero vs Jim Wilson | Sixth | 11½ out |
| Friday, May 23 |
| » Defeated Orioles (14-15), 1-0 | Comiskey Park I (7-6) | 13-18 | Won 2 |
| » Starters: Jack Harshman vs Early Wynn | Sixth | 11½ out |
| Saturday, May 24 |
| » Defeated Orioles (14-16), 4-3 | Comiskey Park I (8-6) | 14-18 | Won 3 |
| » Starters: Billy O'Dell vs Bob Keegan | Sixth | 10½ out |
| Sunday, May 25 |
| » Lost to Red Sox (19-17), 6-3 | Comiskey Park I (8-7) | 14-19 | |
| » Starters: Frank Baumann vs Dick Donovan | Sixth | 11½ out |
| » Defeated Red Sox (19-18), 4-3 | Comiskey Park I (9-7) | 15-19 | |
| » Starters: Bob Smith vs Billy Pierce | Sixth | 11½ out |
| Tuesday, May 27 |
| » Defeated Senators (15-21), 7-3 | Comiskey Park I (10-7) | 16-19 | Won 2 |
| » Starters: Hal Griggs vs Early Wynn | Fifth | 10½ out |
| Wednesday, May 28 |
| » Defeated Senators (15-22), 13-3 | Comiskey Park I (11-7) | 17-19 | Won 3 |
| » Starters: Chuck Stobbs vs Jim Wilson | Fifth | 9½ out |
| Friday, May 30 |
| » Defeated Tigers (18-22), 6-5 | Tiger Stadium (1-2) | 18-19 | Won 4 |
| » Starters: Dick Donovan vs Jim Bunning | Third | 7½ out |
| » Defeated Tigers (18-23), 4-2 | Tiger Stadium (2-2) | 19-19 | Won 5 |
| » Starters: Billy Pierce vs Hank Aguirre | Third | 7½ out |
| Saturday, May 31 |
| » Lost to Tigers (19-23), 3-0 | Tiger Stadium (2-3) | 19-20 | |
| » Starters: Early Wynn vs Paul Foytack | Fourth | 8½ out |
| Monday, June 2 |
| » Lost to Yankees (28-10), 3-0 | Yankee Stadium (0-1) | 19-21 | Lost 2 |
| » Starters: Jim Wilson vs Whitey Ford | Fourth | 10 out |
| Tuesday, June 3 |
| » Lost to Yankees (29-10), 13-0 | Yankee Stadium (0-2) | 19-22 | Lost 3 |
| » Starters: Dick Donovan vs Johnny Kucks | Fifth | 11 out |
| Wednesday, June 4 |
| » Defeated Yankees (29-11), 7-2 | Yankee Stadium (1-2) | 20-22 | |
| » Starters: Billy Pierce vs Tom Sturdivant | Fourth | 10 out |
| Thursday, June 5 |
| » Lost to Yankees (30-11), 12-5 | Yankee Stadium (1-3) | 20-23 | |
| » Starters: Early Wynn vs Don Larsen | Fourth | 10 out |
| » Defeated Yankees (30-12), 3-2 | Yankee Stadium (2-3) | 21-23 | |
| » Starters: Ray Moore vs Bobby Shantz | Fourth | 10 out |
| Friday, June 6 |
| » Lost to Red Sox (23-24), 3-2 | Fenway Park (0-2) | 21-24 | |
| » Starters: Jim Wilson vs Willard Nixon | Fourth | 11 out |
| Saturday, June 7 |
| » Lost to Red Sox (24-24), 7-6 | Fenway Park (0-3) | 21-25 | Lost 2 |
| » Starters: Bob Keegan vs Frank Baumann | Fifth | 12 out |
| Sunday, June 8 |
| » Lost to Red Sox (25-24), 6-5 | Fenway Park (0-4) | 21-26 | Lost 3 |
| » Starters: Billy Pierce vs Tom Brewer | Seventh | 12 out |
| » Lost to Red Sox (26-24), 4-1 | Fenway Park (0-5) | 21-27 | Lost 4 |
| » Starters: Dick Donovan vs Dave Sisler | Seventh | 12 out |
| Tuesday, June 10 |
| » Defeated Senators (23-27), 5-4 | Griffith Stadium (1-1) | 22-27 | |
| » Starters: Ray Moore vs Camilo Pascual | Seventh | 12 out |
| » Lost to Senators (24-27), 5-2 | Griffith Stadium (1-2) | 22-28 | |
| » Starters: Jim Wilson vs Hal Griggs | Seventh | 12 out |
| Wednesday, June 11 |
| » Lost to Senators (25-27), 5-2 | Griffith Stadium (1-3) | 22-29 | Lost 2 |
| » Starters: Bill Fischer vs Russ Kemmerer | Eighth | 13½ out |
| Thursday, June 12 |
| » Lost to Senators (26-27), 6-5 | Griffith Stadium (1-4) | 22-30 | Lost 3 |
| » Starters: Dick Donovan vs Pedro Ramos | Eighth | 14 out |
| Friday, June 13 |
| » Tied Orioles, 5-5 | Memorial Stadium (1-1) | 22-30 | |
| » Starters: Billy Pierce vs Jack Harshman | Eighth | 13½ out |
| Saturday, June 14 |
| » Defeated Orioles (24-28), 9-1 | Memorial Stadium (2-1) | 23-30 | |
| » Starters: Early Wynn vs Billy Loes | Eighth | 12½ out |
| Sunday, June 15 |
| » Defeated Orioles (24-29), 3-0 | Memorial Stadium (3-1) | 24-30 | Won 2 |
| » Starters: Jim Wilson vs Ken Lehman | Seventh | 10½ out |
| » Defeated Orioles (24-30), 4-0 | Memorial Stadium (4-1) | 25-30 | Won 3 |
| » Starters: Dick Donovan vs Arnie Portocarrero | Seventh | 10½ out |
| Tuesday, June 17 |
| » Defeated Red Sox (30-29), 4-0 | Comiskey Park I (12-7) | 26-30 | Won 4 |
| » Starters: Dave Sisler vs Billy Pierce | Sixth | 10½ out |
| Wednesday, June 18 |
| » Lost to Red Sox (31-29), 13-9 | Comiskey Park I (12-8) | 26-31 | |
| » Starters: Tom Brewer vs Ray Moore | Sixth | 11½ out |
| » Major-league debuts: Norm Cash (White Sox) |
| Thursday, June 19 |
| » Defeated Red Sox (31-30), 4-0 | Comiskey Park I (13-8) | 27-31 | |
| » Starters: Frank Sullivan vs Early Wynn | Sixth | 11½ out |
| Friday, June 20 |
| » Defeated Orioles (27-31), 5-3 | Comiskey Park I (14-8) | 28-31 | Won 2 |
| » Starters: Jack Harshman vs Dick Donovan | Fourth | 10½ out |
| Saturday, June 21 |
| » Defeated Orioles (27-32), 1-0 | Comiskey Park I (15-8) | 29-31 | Won 3 |
| » Starters: Billy Loes vs Billy Pierce | Fourth | 9½ out |
| Sunday, June 22 |
| » Lost to Orioles (28-32), 2-0 | Comiskey Park I (15-9) | 29-32 | |
| » Starters: Billy O'Dell vs Jim Wilson | Sixth | 10½ out |
| Monday, June 23 |
| » Defeated Yankees (39-22), 2-0 | Comiskey Park I (16-9) | 30-32 | |
| » Starters: Whitey Ford vs Ray Moore | Fourth | 9½ out |
| Tuesday, June 24 |
| » Lost to Yankees (40-22), 6-2 | Comiskey Park I (16-10) | 30-33 | |
| » Starters: Bob Turley vs Early Wynn | Fifth | 10½ out |
| Thursday, June 26 |
| » Lost to Yankees (41-22), 4-3 | Comiskey Park I (16-11) | 30-34 | Lost 2 |
| » Starters: Johnny Kucks vs Dick Donovan | Fifth | 11½ out |
| Friday, June 27 |
| » Defeated Senators (28-38), 3-0 | Comiskey Park I (17-11) | 31-34 | |
| » Starters: Russ Kemmerer vs Billy Pierce | Fifth | 11½ out |
| Saturday, June 28 |
| » Defeated Senators (28-39), 8-4 | Comiskey Park I (18-11) | 32-34 | Won 2 |
| » Starters: Tex Clevenger vs Jim Wilson | Fifth | 11½ out |
| Sunday, June 29 |
| » Lost to Senators (29-39), 12-0 | Comiskey Park I (18-12) | 32-35 | |
| » Starters: Pedro Ramos vs Ray Moore | Fifth | 11 out |
| » Defeated Senators (29-40), 12-11 | Comiskey Park I (19-12) | 33-35 | |
| » Starters: Jack Spring vs Early Wynn | Fifth | 11 out |
| Monday, June 30 |
| » Lost to Indians (34-38), 5-3 | Comiskey Park I (19-13) | 33-36 | |
| » Starters: Cal McLish vs Dick Donovan | Fifth | 11½ out |
| Tuesday, July 1 |
| » Defeated Indians (34-39), 5-4 | Comiskey Park I (20-13) | 34-36 | |
| » Starters: Ray Narleski vs Billy Pierce | Fifth | 11 out |
| Thursday, July 3 |
| » Defeated Athletics (36-35), 7-2 | Comiskey Park I (21-13) | 35-36 | Won 2 |
| » Starters: Ray Herbert vs Jim Wilson | Fifth | 11½ out |
| Friday, July 4 |
| » Lost to Athletics (37-35), 6-5 | Comiskey Park I (21-14) | 35-37 | |
| » Starters: Murry Dickson vs Early Wynn | Fifth | 13½ out |
| » Lost to Athletics (38-35), 4-3 | Comiskey Park I (21-15) | 35-38 | Lost 2 |
| » Starters: Bud Daley vs Ray Moore | Fifth | 13½ out |
| Saturday, July 5 |
| » Defeated Tigers (36-37), 8-1 | Comiskey Park I (22-15) | 36-38 | |
| » Starters: Frank Lary vs Billy Pierce | Fifth | 13 out |
| Sunday, July 6 |
| » Lost to Tigers (37-37), 2-1 | Comiskey Park I (22-16) | 36-39 | |
| » Starters: Jim Bunning vs Dick Donovan | Fifth | 13 out |
| Monday, July 7 |
| Former White Sox John Sullivan dies in Chicago, IL at the age of 65. |
| Thursday, July 10 |
| » Lost to Red Sox (39-37), 11-2 | Fenway Park (0-6) | 36-40 | Lost 2 |
| » Starters: Early Wynn vs Frank Sullivan | Seventh | 14 out |
| Friday, July 11 |
| » Lost to Red Sox (40-37), 6-1 | Fenway Park (0-7) | 36-41 | Lost 3 |
| » Starters: Jim Wilson vs Ike Delock | Seventh | 15 out |
| Saturday, July 12 |
| » Defeated Red Sox (40-38), 7-4 | Fenway Park (1-7) | 37-41 | |
| » Starters: Dick Donovan vs Dave Sisler | Fifth | 14½ out |
| » Defeated Red Sox (40-39), 13-5 | Fenway Park (2-7) | 38-41 | Won 2 |
| » Starters: Bob Shaw vs Duane Wilson | Fifth | 14½ out |
| Sunday, July 13 |
| » Defeated Yankees (52-27), 7-4 | Yankee Stadium (3-3) | 39-41 | Won 3 |
| » Starters: Billy Pierce vs Don Larsen | Fifth | 14½ out |
| » Lost to Yankees (53-27), 5-4 | Yankee Stadium (3-4) | 39-42 | |
| » Starters: Ray Moore vs Bobby Shantz | Fifth | 14½ out |
| Monday, July 14 |
| » Lost to Yankees (54-27), 5-0 | Yankee Stadium (3-5) | 39-43 | Lost 2 |
| » Starters: Early Wynn vs Whitey Ford | Fifth | 15½ out |
| Tuesday, July 15 |
| » Lost to Orioles (39-42), 4-3 | Memorial Stadium (4-2) | 39-44 | Lost 3 |
| » Starters: Jim Wilson vs Arnie Portocarrero | Fifth | 15½ out |
| Wednesday, July 16 |
| » Defeated Orioles (39-43), 6-1 | Memorial Stadium (5-2) | 40-44 | |
| » Starters: Dick Donovan vs Milt Pappas | Sixth | 16 out |
| » Lost to Orioles (40-43), 6-5 | Memorial Stadium (5-3) | 40-45 | |
| » Starters: Bob Shaw vs Jack Harshman | Sixth | 16 out |
| Thursday, July 17 |
| » Lost to Orioles (41-43), 3-0 | Memorial Stadium (5-4) | 40-46 | Lost 2 |
| » Starters: Billy Pierce vs Billy O'Dell | Sixth | 17 out |
| Friday, July 18 |
| » Defeated Senators (37-49), 9-2 | Griffith Stadium (2-4) | 41-46 | |
| » Starters: Early Wynn vs John Romonosky | Sixth | 16 out |
| Saturday, July 19 |
| » Defeated Senators (37-50), 7-6 | Griffith Stadium (3-4) | 42-46 | Won 2 |
| » Starters: Jim Wilson vs Pedro Ramos | Fifth | 15 out |
| Sunday, July 20 |
| » Defeated Senators (37-51), 4-2 | Griffith Stadium (4-4) | 43-46 | Won 3 |
| » Starters: Dick Donovan vs Russ Kemmerer | Fifth | 16 out |
| » Lost to Senators (38-51), 5-4 | Griffith Stadium (4-5) | 43-47 | |
| » Starters: Ray Moore vs Hal Griggs | Fifth | 16 out |
| Tuesday, July 22 |
| » Defeated Orioles (43-45), 4-2 | Comiskey Park I (23-16) | 44-47 | |
| » Starters: Jack Harshman vs Billy Pierce | Fourth | 16 out |
| Wednesday, July 23 |
| » Lost to Orioles (44-45), 6-4 | Comiskey Park I (23-17) | 44-48 | |
| » Starters: Billy O'Dell vs Early Wynn | Fifth | 17 out |
| Thursday, July 24 |
| » Lost to Orioles (45-45), 7-3 | Comiskey Park I (23-18) | 44-49 | Lost 2 |
| » Starters: Milt Pappas vs Jim Wilson | Fifth | 18 out |
| Friday, July 25 |
| » Defeated Red Sox (47-44), 4-0 | Comiskey Park I (24-18) | 45-49 | |
| » Starters: Frank Sullivan vs Dick Donovan | Fourth | 18 out |
| Saturday, July 26 |
| » Defeated Red Sox (47-45), 11-6 | Comiskey Park I (25-18) | 46-49 | Won 2 |
| » Starters: Ike Delock vs Ray Moore | Third | 18 out |
| Sunday, July 27 |
| » Lost to Red Sox (48-45), 7-3 | Comiskey Park I (25-19) | 46-50 | |
| » Starters: Tom Brewer vs Billy Pierce | Fourth | 17½ out |
| Monday, July 28 |
| » Defeated Senators (42-56), 6-5 | Comiskey Park I (26-19) | 47-50 | |
| » Starters: Jim Constable vs Early Wynn | Fourth | 17½ out |
| Former White Sox Lu Blue dies in Alexandria, VA at the age of 62. |
| Tuesday, July 29 |
| » Defeated Senators (42-57), 2-1 | Comiskey Park I (27-19) | 48-50 | Won 2 |
| » Starters: Russ Kemmerer vs Dick Donovan | Fourth | 16½ out |
| Wednesday, July 30 |
| » Defeated Senators (42-58), 11-9 | Comiskey Park I (28-19) | 49-50 | Won 3 |
| » Starters: John Romonosky vs Jim Wilson | Fourth | 15½ out |
| Future White Sox Scott Fletcher is born in Fort Walton Beach, FL. |
| Friday, August 1 |
| » Lost to Yankees (66-34), 7-0 | Comiskey Park I (28-20) | 49-51 | |
| » Starters: Bob Turley vs Billy Pierce | Fourth | 17 out |
| Former White Sox Ike Boone dies in Northport, AL at the age of 62. |
| Saturday, August 2 |
| » Lost to Yankees (67-34), 6-1 | Comiskey Park I (28-21) | 49-52 | Lost 2 |
| » Starters: Art Ditmar vs Early Wynn | Fifth | 18 out |
| Sunday, August 3 |
| » Defeated Yankees (67-35), 3-1 | Comiskey Park I (29-21) | 50-52 | |
| » Starters: Whitey Ford vs Dick Donovan | Third | 16 out |
| » Defeated Yankees (67-36), 4-0 | Comiskey Park I (30-21) | 51-52 | Won 2 |
| » Starters: Johnny Kucks vs Ray Moore | Third | 16 out |
| Tuesday, August 5 |
| » Defeated Athletics (47-54), 5-4 | Municipal Stadium (4-3) | 52-52 | Won 3 |
| » Starters: Jim Wilson vs Bob Grim | Third | 16½ out |
| Future White Sox Reid Nichols is born in Ocala, FL. |
| Wednesday, August 6 |
| » Defeated Athletics (47-55), 4-2 | Municipal Stadium (5-3) | 53-52 | Won 4 |
| » Starters: Billy Pierce vs Bob Davis | Third | 16½ out |
| Friday, August 8 |
| » Lost to Tigers (51-53), 6-2 | Tiger Stadium (2-4) | 53-53 | |
| » Starters: Early Wynn vs Frank Lary | Third | 17½ out |
| Saturday, August 9 |
| » Defeated Tigers (51-54), 9-3 | Tiger Stadium (3-4) | 54-53 | |
| » Starters: Dick Donovan vs Herb Moford | Third | 16½ out |
| Sunday, August 10 |
| » Defeated Tigers (51-55), 5-2 | Tiger Stadium (4-4) | 55-53 | Won 2 |
| » Starters: Ray Moore vs Paul Foytack | Third | 16½ out |
| » Lost to Tigers (52-55), 4-3 | Tiger Stadium (4-5) | 55-54 | |
| » Starters: Barry Latman vs Billy Hoeft | Third | 16½ out |
| Monday, August 11 |
| » Defeated Indians (55-56), 3-1 | Cleveland Stadium (3-4) | 56-54 | |
| » Starters: Billy Pierce vs Ray Narleski | Second | 15 out |
| Tuesday, August 12 |
| » Defeated Indians (55-57), 4-1 | Cleveland Stadium (4-4) | 57-54 | Won 2 |
| » Starters: Early Wynn vs Mudcat Grant | Second | 15 out |
| Wednesday, August 13 |
| » Lost to Athletics (49-60), 2-1 | Comiskey Park I (30-22) | 57-55 | |
| » Starters: Ned Garver vs Dick Donovan | Second | 14½ out |
| » Defeated Athletics (49-61), 6-5 | Comiskey Park I (31-22) | 58-55 | |
| » Starters: Murry Dickson vs Jim Wilson | Second | 14½ out |
| Thursday, August 14 |
| » Defeated Athletics (49-62), 5-2 | Comiskey Park I (32-22) | 59-55 | Won 2 |
| » Starters: Bud Daley vs Ray Moore | Second | 14½ out |
| Friday, August 15 |
| » Defeated Indians (56-60), 4-3 | Comiskey Park I (33-22) | 60-55 | Won 3 |
| » Starters: Hal Woodeshick vs Barry Latman | Second | 13½ out |
| Future White Sox Joe Cowley is born in Lexington, KY. Future White Sox Randy Johnson is born in Miami, FL. |
| Saturday, August 16 |
| » Defeated Indians (56-61), 7-6 | Comiskey Park I (34-22) | 61-55 | Won 4 |
| » Starters: Don Ferrarese vs Early Wynn | Second | 12½ out |
| Sunday, August 17 |
| » Defeated Indians (56-62), 3-2 | Comiskey Park I (35-22) | 62-55 | Won 5 |
| » Starters: Mudcat Grant vs Billy Pierce | Second | 11½ out |
| Tuesday, August 19 |
| » Defeated Red Sox (59-57), 7-1 | Fenway Park (3-7) | 63-55 | Won 6 |
| » Starters: Dick Donovan vs Frank Sullivan | Second | 10½ out |
| Wednesday, August 20 |
| » Defeated Red Sox (59-58), 10-8 | Fenway Park (4-7) | 64-55 | Won 7 |
| » Starters: Jim Wilson vs Ted Bowsfield | Second | 10½ out |
| Thursday, August 21 |
| » Lost to Yankees (76-45), 6-3 | Yankee Stadium (3-6) | 64-56 | |
| » Starters: Ray Moore vs Bob Turley | Second | 11½ out |
| Friday, August 22 |
| » Lost to Yankees (77-45), 8-5 | Yankee Stadium (3-7) | 64-57 | Lost 2 |
| » Starters: Early Wynn vs Johnny Kucks | Second | 12½ out |
| Saturday, August 23 |
| » Defeated Yankees (77-46), 7-1 | Yankee Stadium (4-7) | 65-57 | |
| » Starters: Billy Pierce vs Whitey Ford | Second | 11½ out |
| Future White Sox Julio Franco is born in Hato Mayor, D.R. |
| Sunday, August 24 |
| » Lost to Orioles (59-62), 5-2 | Memorial Stadium (5-5) | 65-58 | |
| » Starters: Dick Donovan vs Billy O'Dell | Second | 12 out |
| Monday, August 25 |
| » Lost to Orioles (60-62), 6-5 | Memorial Stadium (5-6) | 65-59 | Lost 2 |
| » Starters: Ray Moore vs Jack Harshman | Second | 12½ out |
| Tuesday, August 26 |
| » Defeated Senators (52-72), 5-2 | Griffith Stadium (5-5) | 66-59 | |
| » Starters: Early Wynn vs Russ Kemmerer | Second | 12½ out |
| Wednesday, August 27 |
| » Defeated Senators (52-73), 2-1 | Griffith Stadium (6-5) | 67-59 | Won 2 |
| » Starters: Billy Pierce vs Camilo Pascual | Second | 11½ out |
| Friday, August 29 |
| » Defeated Tigers (60-65), 3-0 | Comiskey Park I (36-22) | 68-59 | Won 3 |
| » Starters: Herb Moford vs Dick Donovan | Second | 10½ out |
| Saturday, August 30 |
| » Lost to Tigers (61-65), 6-3 | Comiskey Park I (36-23) | 68-60 | |
| » Starters: Frank Lary vs Ray Moore | Second | 10½ out |
| Sunday, August 31 |
| » Defeated Tigers (61-66), 3-0 | Comiskey Park I (37-23) | 69-60 | |
| » Starters: Jim Bunning vs Early Wynn | Second | 10½ out |
| Monday, September 1 |
| » Lost to Indians (63-68), 6-5 | Comiskey Park I (37-24) | 69-61 | |
| » Starters: Don Ferrarese vs Billy Pierce | Second | 11½ out |
| » Lost to Indians (64-68), 7-1 | Comiskey Park I (37-25) | 69-62 | Lost 2 |
| » Starters: Gary Bell vs Bob Shaw | Second | 11½ out |
| Wednesday, September 3 |
| » Defeated Tigers (64-67), 1-0 | Tiger Stadium (5-5) | 70-62 | |
| » Starters: Dick Donovan vs Frank Lary | Second | 12 out |
| Thursday, September 4 |
| » Lost to Tigers (65-67), 11-4 | Tiger Stadium (5-6) | 70-63 | |
| » Starters: Ray Moore vs Jim Bunning | Second | 12½ out |
| Friday, September 5 |
| » Defeated Indians (64-71), 4-3 | Cleveland Stadium (5-4) | 71-63 | |
| » Starters: Early Wynn vs Don Mossi | Second | 11½ out |
| Saturday, September 6 |
| » Lost to Indians (65-71), 7-1 | Cleveland Stadium (5-5) | 71-64 | |
| » Starters: Billy Pierce vs Gary Bell | Second | 11½ out |
| Sunday, September 7 |
| » Lost to Indians (66-71), 4-3 | Cleveland Stadium (5-6) | 71-65 | Lost 2 |
| » Starters: Dick Donovan vs Don Ferrarese | Second | 12 out |
| Tuesday, September 9 |
| » Defeated Red Sox (70-66), 4-1 | Comiskey Park I (38-25) | 72-65 | |
| » Starters: Frank Sullivan vs Early Wynn | Second | 11 out |
| » Major-league debuts: Johnny Callison (White Sox) |
| Wednesday, September 10 |
| » Defeated Red Sox (70-67), 7-2 | Comiskey Park I (39-25) | 73-65 | Won 2 |
| » Starters: Tom Brewer vs Billy Pierce | Second | 11 out |
| Thursday, September 11 |
| » Defeated Red Sox (70-68), 4-1 | Comiskey Park I (40-25) | 74-65 | Won 3 |
| » Starters: Ike Delock vs Dick Donovan | Second | 10½ out |
| Future White Sox Don Slaught is born in Long Beach, CA. |
| Friday, September 12 |
| » Lost to Yankees (86-55), 5-0 | Comiskey Park I (40-26) | 74-66 | |
| » Starters: Bob Turley vs Ray Moore | Second | 11½ out |
| » Major-league debuts: Johnny Romano (White Sox) |
| Saturday, September 13 |
| » Lost to Yankees (87-55), 5-4 | Comiskey Park I (40-27) | 74-67 | Lost 2 |
| » Starters: Bobby Shantz vs Early Wynn | Second | 12½ out |
| Sunday, September 14 |
| » Defeated Senators (61-81), 7-1 | Comiskey Park I (41-27) | 75-67 | |
| » Starters: Bill Fischer vs Billy Pierce | Second | 12½ out |
| » Defeated Senators (61-82), 6-5 | Comiskey Park I (42-27) | 76-67 | Won 2 |
| » Starters: Russ Kemmerer vs Jim Wilson | Second | 12½ out |
| Tuesday, September 16 |
| » Defeated Orioles (67-76), 4-3 | Comiskey Park I (43-27) | 77-67 | Won 3 |
| » Starters: Billy O'Dell vs Dick Donovan | Second | 11½ out |
| Thursday, September 18 |
| » Defeated Orioles (67-77), 6-2 | Comiskey Park I (44-27) | 78-67 | Won 4 |
| » Starters: Jack Harshman vs Ray Moore | Second | 10½ out |
| Friday, September 19 |
| » Lost to Athletics (70-77), 7-6 | Municipal Stadium (5-4) | 78-68 | |
| » Starters: Early Wynn vs Ralph Terry | Second | 10½ out |
| Saturday, September 20 |
| » Lost to Athletics (71-77), 3-2 | Municipal Stadium (5-5) | 78-69 | Lost 2 |
| » Starters: Billy Pierce vs Bob Grim | Second | 10½ out |
| Sunday, September 21 |
| » Defeated Athletics (71-78), 2-1 | Municipal Stadium (6-5) | 79-69 | |
| » Starters: Dick Donovan vs Ray Herbert | Second | 9½ out |
| Tuesday, September 23 |
| » Lost to Tigers (75-74), 3-1 | Comiskey Park I (44-28) | 79-70 | |
| » Starters: Paul Foytack vs Early Wynn | Second | 9½ out |
| Wednesday, September 24 |
| » Defeated Tigers (75-75), 4-3 | Comiskey Park I (45-28) | 80-70 | |
| » Starters: Frank Lary vs Billy Pierce | Second | 9½ out |
| Thursday, September 25 |
| » Lost to Tigers (76-75), 7-1 | Comiskey Park I (45-29) | 80-71 | |
| » Starters: Jim Bunning vs Dick Donovan | Second | 10 out |
| Friday, September 26 |
| » Defeated Athletics (72-80), 1-0 | Comiskey Park I (46-29) | 81-71 | |
| » Starters: Bob Grim vs Barry Latman | Second | 9 out |
| Saturday, September 27 |
| » Lost to Athletics (73-80), 2-1 | Comiskey Park I (46-30) | 81-72 | |
| » Starters: Howie Reed vs Early Wynn | Second | 9½ out |
| Sunday, September 28 |
| » Defeated Athletics (73-81), 11-4 | Comiskey Park I (47-30) | 82-72 | |
| » Starters: John Tsitouris vs Stover McIlwain | Second | 10 out |
| » Major-league debuts: Chuck Lindstrom (White |
