| Monday, January 20 |
| Future Tiger Bill Scherrer is born in Tonawanda, NY. |
| Thursday, February 13 |
| Future Tiger Frank Williams is born in Seattle, WA. |
| Friday, February 21 |
| Future Tiger Alan Trammell is born in Garden Grove, CA. |
| Sunday, February 23 |
| Future Tiger John Shelby is born in Lexington, KY. |
| Tuesday, March 25 |
| Former Tiger Al Shaw dies in Uhrichsville, OH at the age of 84. |
| Saturday, March 29 |
| Former Tiger Jimmy Archer dies in Milwaukee, WI at the age of 75. |
| Thursday, April 3 |
| Future Tiger Gary Pettis is born in Oakland, CA. |
| Monday, April 14 |
| » Major-league debuts: Albie Pearson (Senators) |
| Tuesday, April 15 |
| » Defeated White Sox (0-1), 4-3 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Jim Bunning vs Billy Pierce | First | -- |
| Wednesday, April 16 |
| » Defeated White Sox (0-2), 5-4 | Comiskey Park I (2-0) | 2-0 | Won 2 |
| » Starters: Tom Morgan vs Dick Donovan | First | -- |
| Thursday, April 17 |
| » Lost to White Sox (1-2), 4-3 | Comiskey Park I (2-1) | 2-1 | |
| » Starters: Frank Lary vs Early Wynn | Second | ½ out |
| Friday, April 18 |
| » Lost to Indians (2-2), 7-5 | Tiger Stadium (0-1) | 2-2 | Lost 2 |
| » Starters: Herb Score vs Billy Hoeft | Third | 1 out |
| Saturday, April 19 |
| » Defeated Indians (2-3), 9-1 | Tiger Stadium (1-1) | 3-2 | |
| » Starters: Don Mossi vs Paul Foytack | Second | 1 out |
| Sunday, April 20 |
| » Lost to Indians (3-3), 4-2 | Tiger Stadium (1-2) | 3-3 | |
| » Starters: Ray Narleski vs Jim Bunning | Third | 2 out |
| Monday, April 21 |
| » Defeated White Sox (2-4), 2-1 | Tiger Stadium (2-2) | 4-3 | |
| » Starters: Dick Donovan vs Frank Lary | Fourth | 2 out |
| Tuesday, April 22 |
| » Defeated White Sox (2-5), 8-2 | Tiger Stadium (3-2) | 5-3 | Won 2 |
| » Starters: Early Wynn vs Billy Hoeft | Third | 2 out |
| Wednesday, April 23 |
| » Defeated Athletics (5-3), 8-2 | Municipal Stadium (1-0) | 6-3 | Won 3 |
| » Starters: Paul Foytack vs Duke Maas | Second | 1 out |
| Thursday, April 24 |
| » Lost to Athletics (6-3), 7-2 | Municipal Stadium (1-1) | 6-4 | |
| » Starters: Bob Shaw vs Wally Burnette | Third | 1½ out |
| Future Tiger Bill Krueger is born in Waukegan, IL. |
| Friday, April 25 |
| » Lost to Indians (6-5), 12-2 | Cleveland Stadium (0-1) | 6-5 | Lost 2 |
| » Starters: Jim Bunning vs Ray Narleski | Fourth | 1½ out |
| Saturday, April 26 |
| » Lost to Indians (7-5), 4-1 | Cleveland Stadium (0-2) | 6-6 | Lost 3 |
| » Starters: Frank Lary vs Mudcat Grant | Fifth | 2½ out |
| Sunday, April 27 |
| » Defeated Indians (7-6), 9-5 | Cleveland Stadium (1-2) | 7-6 | |
| » Starters: Billy Hoeft vs Mike Garcia | Fourth | 2 out |
| Tuesday, April 29 |
| » Lost to Yankees (9-3), 5-1 | Yankee Stadium (0-1) | 7-7 | |
| » Starters: Paul Foytack vs Bobby Shantz | Fifth | 3 out |
| Wednesday, April 30 |
| » Defeated Yankees (9-4), 10-1 | Yankee Stadium (1-1) | 8-7 | |
| » Starters: Frank Lary vs Whitey Ford | Fourth | 2 out |
| » Major-league debuts: Fritz Brickell (Yankees) |
| Friday, May 2 |
| » Lost to Red Sox (6-10), 6-0 | Fenway Park (0-1) | 8-8 | |
| » Starters: Jim Bunning vs Dave Sisler | Fifth | 3 out |
| Sunday, May 4 |
| » Lost to Orioles (7-8), 4-3 | Memorial Stadium (0-1) | 8-9 | Lost 2 |
| » Starters: Paul Foytack vs Milt Pappas | Sixth | 4 out |
| » Lost to Orioles (8-8), 4-0 | Memorial Stadium (0-2) | 8-10 | Lost 3 |
| » Starters: Billy Hoeft vs Jack Harshman | Sixth | 4 out |
| Monday, May 5 |
| Future Tiger Dave Gumpert is born in South Haven, MI. |
| Wednesday, May 7 |
| » Defeated Senators (9-6), 5-1 | Griffith Stadium (1-0) | 9-10 | |
| » Starters: Frank Lary vs Camilo Pascual | Sixth | 4 out |
| » Lost to Senators (10-6), 11-4 | Griffith Stadium (1-1) | 9-11 | |
| » Starters: Jim Bunning vs Hal Griggs | Sixth | 4 out |
| Thursday, May 8 |
| » Lost to Senators (11-6), 4-1 | Griffith Stadium (1-2) | 9-12 | Lost 2 |
| » Starters: Bob Shaw vs Ralph Lumenti | Seventh | 4½ out |
| Friday, May 9 |
| » Defeated Athletics (8-8), 7-1 | Tiger Stadium (4-2) | 10-12 | |
| » Starters: Ned Garver vs Paul Foytack | Sixth | 4½ out |
| Saturday, May 10 |
| » Defeated Athletics (8-9), 3-2 | Tiger Stadium (5-2) | 11-12 | Won 2 |
| » Starters: Ralph Terry vs Billy Hoeft | Fourth | 4½ out |
| Sunday, May 11 |
| » Defeated Athletics (8-10), 10-3 | Tiger Stadium (6-2) | 12-12 | Won 3 |
| » Starters: Jack Urban vs Jim Bunning | Fourth | 4 out |
| Future Tiger Mark Huismann is born in Littleton, CO. Future Tiger Walt Terrell is born in Jeffersonville, IN. |
| Tuesday, May 13 |
| » Defeated Indians (11-14), 11-1 | Tiger Stadium (7-2) | 13-12 | Won 4 |
| » Starters: Mudcat Grant vs Frank Lary | Fourth | 4 out |
| Wednesday, May 14 |
| » Lost to Indians (12-14), 9-8 | Tiger Stadium (7-3) | 13-13 | |
| » Starters: Hoyt Wilhelm vs Paul Foytack | Fourth | 5 out |
| Thursday, May 15 |
| » Lost to Indians (13-14), 8-5 | Tiger Stadium (7-4) | 13-14 | Lost 2 |
| » Starters: Ray Narleski vs Billy Hoeft | Fourth | 5½ out |
| Friday, May 16 |
| » Lost to Athletics (11-12), 5-3 | Municipal Stadium (1-2) | 13-15 | Lost 3 |
| » Starters: Herm Wehmeier vs Ralph Terry | Fifth | 6½ out |
| Saturday, May 17 |
| » Lost to Athletics (12-12), 4-3 | Municipal Stadium (1-3) | 13-16 | Lost 4 |
| » Starters: Frank Lary vs Jack Urban | Fourth | 7½ out |
| Sunday, May 18 |
| » Lost to Athletics (13-12), 2-0 | Municipal Stadium (1-4) | 13-17 | Lost 5 |
| » Starters: Paul Foytack vs Duke Maas | Seventh | 9 out |
| Tuesday, May 20 |
| » Lost to Orioles (13-13), 6-4 | Tiger Stadium (7-5) | 13-18 | Lost 6 |
| » Starters: Billy O'Dell vs Billy Hoeft | Seventh | 10 out |
| Wednesday, May 21 |
| » Lost to Orioles (14-13), 8-1 | Tiger Stadium (7-6) | 13-19 | Lost 7 |
| » Starters: Connie Johnson vs Frank Lary | Sixth | 11 out |
| Thursday, May 22 |
| » Lost to Yankees (22-5), 5-4 | Tiger Stadium (7-7) | 13-20 | Lost 8 |
| » Starters: Bobby Shantz vs Paul Foytack | Seventh | 12 out |
| Friday, May 23 |
| » Lost to Yankees (23-5), 8-1 | Tiger Stadium (7-8) | 13-21 | Lost 9 |
| » Starters: Bob Turley vs Billy Hoeft | Seventh | 13 out |
| Saturday, May 24 |
| » Defeated Yankees (23-6), 3-2 | Tiger Stadium (8-8) | 14-21 | |
| » Starters: Sal Maglie vs Frank Lary | Seventh | 12 out |
| Sunday, May 25 |
| » Defeated Senators (15-19), 7-2 | Tiger Stadium (9-8) | 15-21 | Won 2 |
| » Starters: Russ Kemmerer vs Jim Bunning | Seventh | 12 out |
| » Defeated Senators (15-20), 6-3 | Tiger Stadium (10-8) | 16-21 | Won 3 |
| » Starters: Al Cicotte vs Hank Aguirre | Seventh | 12 out |
| Tuesday, May 27 |
| » Defeated Red Sox (19-19), 3-2 | Tiger Stadium (11-8) | 17-21 | Won 4 |
| » Starters: Tom Brewer vs Paul Foytack | Sixth | 11 out |
| Wednesday, May 28 |
| » Defeated Red Sox (19-20), 4-2 | Tiger Stadium (12-8) | 18-21 | Won 5 |
| » Starters: Willard Nixon vs Frank Lary | Sixth | 10 out |
| Friday, May 30 |
| » Lost to White Sox (18-19), 6-5 | Tiger Stadium (12-9) | 18-22 | |
| » Starters: Dick Donovan vs Jim Bunning | Sixth | 10 out |
| » Lost to White Sox (19-19), 4-2 | Tiger Stadium (12-10) | 18-23 | Lost 2 |
| » Starters: Billy Pierce vs Hank Aguirre | Sixth | 10 out |
| Saturday, May 31 |
| » Defeated White Sox (19-20), 3-0 | Tiger Stadium (13-10) | 19-23 | |
| » Starters: Early Wynn vs Paul Foytack | Sixth | 10 out |
| Tuesday, June 3 |
| » Lost to Orioles (17-23), 2-0 | Memorial Stadium (0-3) | 19-24 | |
| » Starters: Jim Bunning vs Arnie Portocarrero | Sixth | 12 out |
| Wednesday, June 4 |
| » Lost to Orioles (18-23), 6-4 | Memorial Stadium (0-4) | 19-25 | Lost 2 |
| » Starters: Frank Lary vs Connie Johnson | Seventh | 12 out |
| Thursday, June 5 |
| » Defeated Orioles (18-24), 6-3 | Memorial Stadium (1-4) | 20-25 | |
| » Starters: Paul Foytack vs Billy O'Dell | Seventh | 11½ out |
| Friday, June 6 |
| » Defeated Senators (21-26), 11-2 | Griffith Stadium (2-2) | 21-25 | Won 2 |
| » Starters: Billy Hoeft vs Hal Griggs | Sixth | 11½ out |
| Saturday, June 7 |
| » Lost to Senators (22-26), 4-3 | Griffith Stadium (2-3) | 21-26 | |
| » Starters: Jim Bunning vs Russ Kemmerer | Seventh | 12½ out |
| Sunday, June 8 |
| » Lost to Senators (23-26), 4-3 | Griffith Stadium (2-4) | 21-27 | Lost 2 |
| » Starters: George Susce vs Pedro Ramos | Seventh | 12 out |
| Monday, June 9 |
| » Lost to Red Sox (27-24), 9-4 | Fenway Park (0-2) | 21-28 | Lost 3 |
| » Starters: Paul Foytack vs Frank Sullivan | Eighth | 12½ out |
| Wednesday, June 11 |
| » Defeated Red Sox (27-25), 7-0 | Fenway Park (1-2) | 22-28 | |
| » Manager: Bill Norman |
| » Starters: Frank Lary vs Mike Fornieles | Seventh | 12½ out |
| » Defeated Red Sox (27-26), 9-3 | Fenway Park (2-2) | 23-28 | Won 2 |
| » Starters: Jim Bunning vs Murray Wall | Seventh | 12½ out |
| Thursday, June 12 |
| » Lost to Red Sox (28-26), 4-2 | Fenway Park (2-3) | 23-29 | |
| » Starters: Paul Foytack vs Dave Sisler | Seventh | 13 out |
| Friday, June 13 |
| » Defeated Yankees (35-16), 4-2 | Yankee Stadium (2-1) | 24-29 | |
| » Starters: Billy Hoeft vs Bobby Shantz | Seventh | 12 out |
| Saturday, June 14 |
| » Defeated Yankees (35-17), 5-4 | Yankee Stadium (3-1) | 25-29 | Won 2 |
| » Starters: George Susce vs Johnny Kucks | Sixth | 11 out |
| Sunday, June 15 |
| » Defeated Yankees (35-18), 2-0 | Yankee Stadium (4-1) | 26-29 | Won 3 |
| » Starters: Frank Lary vs Don Larsen | Fifth | 9 out |
| » Defeated Yankees (35-19), 3-0 | Yankee Stadium (5-1) | 27-29 | Won 4 |
| » Starters: Jim Bunning vs Bob Turley | Fifth | 9 out |
| Tuesday, June 17 |
| » Defeated Senators (26-32), 9-2 | Tiger Stadium (14-10) | 28-29 | Won 5 |
| » Starters: Pedro Ramos vs Billy Hoeft | Fourth | 9 out |
| Wednesday, June 18 |
| » Major-league debuts: Norm Cash (White Sox) |
| Thursday, June 19 |
| » Lost to Senators (27-32), 4-3 | Tiger Stadium (14-11) | 28-30 | |
| » Starters: Russ Kemmerer vs Paul Foytack | Third | 10½ out |
| Friday, June 20 |
| » Defeated Yankees (38-20), 7-1 | Tiger Stadium (15-11) | 29-30 | |
| » Starters: Bob Turley vs Jim Bunning | Third | 9½ out |
| Saturday, June 21 |
| » Defeated Yankees (38-21), 1-0 | Tiger Stadium (16-11) | 30-30 | Won 2 |
| » Starters: Duke Maas vs Frank Lary | Second | 8½ out |
| Sunday, June 22 |
| » Lost to Yankees (39-21), 15-0 | Tiger Stadium (16-12) | 30-31 | |
| » Starters: Don Larsen vs Billy Hoeft | Third | 9½ out |
| Monday, June 23 |
| » Defeated Orioles (28-33), 3-1 | Tiger Stadium (17-12) | 31-31 | |
| » Starters: Arnie Portocarrero vs George Susce | Third | 8½ out |
| Former Tiger George Boehler dies in Lawrenceburg, IN at the age of 67. |
| Tuesday, June 24 |
| » Defeated Orioles (28-34), 5-0 | Tiger Stadium (18-12) | 32-31 | Won 2 |
| » Starters: Milt Pappas vs Paul Foytack | Third | 8½ out |
| Thursday, June 26 |
| » Lost to Orioles (29-34), 2-0 | Tiger Stadium (18-13) | 32-32 | |
| » Starters: Jack Harshman vs Billy Hoeft | Third | 9½ out |
| Friday, June 27 |
| » Defeated Red Sox (33-34), 7-4 | Tiger Stadium (19-13) | 33-32 | |
| » Starters: Tom Brewer vs Frank Lary | Third | 9½ out |
| Saturday, June 28 |
| » Lost to Red Sox (34-34), 6-5 | Tiger Stadium (19-14) | 33-33 | |
| » Starters: Dave Sisler vs Jim Bunning | Third | 10½ out |
| Sunday, June 29 |
| » Lost to Red Sox (35-34), 10-7 | Tiger Stadium (19-15) | 33-34 | Lost 2 |
| » Starters: Frank Sullivan vs Paul Foytack | Fourth | 10½ out |
| Monday, June 30 |
| » Defeated Athletics (35-33), 7-6 | Tiger Stadium (20-15) | 34-34 | |
| » Starters: Jack Urban vs George Susce | Fourth | 10 out |
| Tuesday, July 1 |
| » Lost to Athletics (36-33), 5-1 | Tiger Stadium (20-16) | 34-35 | |
| » Starters: Ned Garver vs Frank Lary | Fourth | 10½ out |
| Wednesday, July 2 |
| » Defeated Athletics (36-34), 5-0 | Tiger Stadium (21-16) | 35-35 | |
| » Starters: Ralph Terry vs Jim Bunning | Fourth | 10½ out |
| Friday, July 4 |
| » Lost to Indians (35-39), 6-1 | Cleveland Stadium (1-3) | 35-36 | |
| » Starters: Paul Foytack vs Cal McLish | Third | 12 out |
| » Defeated Indians (35-40), 3-1 | Cleveland Stadium (2-3) | 36-36 | |
| » Starters: Herm Wehmeier vs Mudcat Grant | Third | 12 out |
| Saturday, July 5 |
| » Lost to White Sox (36-38), 8-1 | Comiskey Park I (2-2) | 36-37 | |
| » Starters: Frank Lary vs Billy Pierce | Fourth | 12½ out |
| Sunday, July 6 |
| » Defeated White Sox (36-39), 2-1 | Comiskey Park I (3-2) | 37-37 | |
| » Starters: Jim Bunning vs Dick Donovan | Third | 11½ out |
| Thursday, July 10 |
| » Lost to Senators (32-45), 5-3 | Griffith Stadium (2-5) | 37-38 | |
| » Starters: Frank Lary vs Pedro Ramos | Fourth | 12½ out |
| Friday, July 11 |
| » Lost to Senators (33-45), 6-5 | Griffith Stadium (2-6) | 37-39 | Lost 2 |
| » Starters: Jim Bunning vs Russ Kemmerer | Fourth | 13½ out |
| Saturday, July 12 |
| » Defeated Senators (33-46), 3-1 | Griffith Stadium (3-6) | 38-39 | |
| » Starters: Herm Wehmeier vs Hal Griggs | Third | 13½ out |
| Sunday, July 13 |
| » Defeated Orioles (37-41), 6-5 | Memorial Stadium (2-4) | 39-39 | Won 2 |
| » Starters: Paul Foytack vs Charlie Beamon | Second | 12½ out |
| » Defeated Orioles (37-42), 5-3 | Memorial Stadium (3-4) | 40-39 | Won 3 |
| » Starters: George Susce vs Billy O'Dell | Second | 12½ out |
| Monday, July 14 |
| » Lost to Orioles (38-42), 2-1 | Memorial Stadium (3-5) | 40-40 | |
| » Starters: Herb Moford vs Hal Brown | Third | 13½ out |
| Tuesday, July 15 |
| » Defeated Yankees (54-28), 12-5 | Yankee Stadium (6-1) | 41-40 | |
| » Starters: Frank Lary vs Zach Monroe | Third | 12½ out |
| Wednesday, July 16 |
| » Lost to Yankees (55-28), 3-2 | Yankee Stadium (6-2) | 41-41 | |
| » Starters: Jim Bunning vs Bob Turley | Third | 13½ out |
| Thursday, July 17 |
| » Lost to Yankees (56-28), 4-2 | Yankee Stadium (6-3) | 41-42 | Lost 2 |
| » Starters: Billy Hoeft vs Art Ditmar | Third | 14½ out |
| Friday, July 18 |
| » Lost to Red Sox (45-40), 11-9 | Fenway Park (2-4) | 41-43 | Lost 3 |
| » Starters: Paul Foytack vs Bill Monbouquette | Third | 14½ out |
| » Major-league debuts: Bill Monboquette (Red Sox) |
| Saturday, July 19 |
| » Lost to Red Sox (46-40), 7-6 | Fenway Park (2-5) | 41-44 | Lost 4 |
| » Starters: Frank Lary vs Dave Sisler | Fourth | 14½ out |
| Sunday, July 20 |
| » Defeated Red Sox (46-41), 3-0 | Fenway Park (3-5) | 42-44 | |
| » Starters: Jim Bunning vs Frank Sullivan | Fourth | 15½ out |
| » Lost to Red Sox (47-41), 5-2 | Fenway Park (3-6) | 42-45 | |
| » Starters: George Susce vs Ike Delock | Fourth | 15½ out |
| » Major-league debuts: Ted Bowsfield (Red Sox) |
| Tuesday, July 22 |
| » Lost to Yankees (59-30), 13-3 | Tiger Stadium (21-17) | 42-46 | Lost 2 |
| » Starters: Bob Turley vs Paul Foytack | Fifth | 16½ out |
| Wednesday, July 23 |
| » Lost to Yankees (60-30), 16-4 | Tiger Stadium (21-18) | 42-47 | Lost 3 |
| » Starters: Art Ditmar vs Frank Lary | Sixth | 17½ out |
| Thursday, July 24 |
| » Lost to Yankees (61-30), 10-7 | Tiger Stadium (21-19) | 42-48 | Lost 4 |
| » Starters: Don Larsen vs Jim Bunning | Seventh | 18½ out |
| Friday, July 25 |
| » Lost to Senators (40-54), 4-3 | Tiger Stadium (21-20) | 42-49 | Lost 5 |
| » Starters: Russ Kemmerer vs George Susce | Seventh | 19½ out |
| Saturday, July 26 |
| » Defeated Senators (40-55), 9-1 | Tiger Stadium (22-20) | 43-49 | |
| » Starters: John Romonosky vs Herb Moford | Fifth | 19½ out |
| Sunday, July 27 |
| » Lost to Senators (41-55), 4-3 | Tiger Stadium (22-21) | 43-50 | |
| » Starters: Camilo Pascual vs Frank Lary | Seventh | 19½ out |
| » Lost to Senators (42-55), 6-1 | Tiger Stadium (22-22) | 43-51 | Lost 2 |
| » Starters: Pedro Ramos vs Hank Aguirre | Seventh | 19½ out |
| Monday, July 28 |
| » Defeated Red Sox (48-46), 5-4 | Tiger Stadium (23-22) | 44-51 | |
| » Starters: Dave Sisler vs Al Cicotte | Seventh | 19½ out |
| Former Tiger Lu Blue dies in Alexandria, VA at the age of 62. |
| Tuesday, July 29 |
| » Lost to Red Sox (49-46), 11-8 | Tiger Stadium (23-23) | 44-52 | |
| » Starters: Frank Sullivan vs Jim Bunning | Seventh | 19½ out |
| Wednesday, July 30 |
| » Defeated Red Sox (49-47), 2-1 | Tiger Stadium (24-23) | 45-52 | |
| » Starters: Ike Delock vs George Susce | Seventh | 18½ out |
| » Major-league debuts: Coot Veal (Tigers) |
| Future Tiger Scott Fletcher is born in Fort Walton Beach, FL. |
| Thursday, July 31 |
| » Defeated Red Sox (49-48), 3-2 | Tiger Stadium (25-23) | 46-52 | Won 2 |
| » Starters: Bill Monbouquette vs Frank Lary | Seventh | 18½ out |
| Friday, August 1 |
| » Defeated Orioles (47-49), 3-1 | Tiger Stadium (26-23) | 47-52 | Won 3 |
| » Starters: Jack Harshman vs Herb Moford | Sixth | 18½ out |
| Saturday, August 2 |
| » Defeated Orioles (47-50), 8-7 | Tiger Stadium (27-23) | 48-52 | Won 4 |
| » Starters: Billy O'Dell vs Jim Bunning | Sixth | 18½ out |
| Sunday, August 3 |
| » Defeated Orioles (47-51), 3-2 | Tiger Stadium (28-23) | 49-52 | Won 5 |
| » Starters: Milt Pappas vs Paul Foytack | Fourth | 16½ out |
| » Defeated Orioles (47-52), 4-1 | Tiger Stadium (29-23) | 50-52 | Won 6 |
| » Starters: Hal Brown vs Billy Hoeft | Fourth | 16½ out |
| Tuesday, August 5 |
| » Lost to Indians (52-54), 6-1 | Tiger Stadium (29-24) | 50-53 | |
| » Starters: Cal McLish vs George Susce | Fifth | 18 out |
| Friday, August 8 |
| » Defeated White Sox (53-53), 6-2 | Tiger Stadium (30-24) | 51-53 | |
| » Starters: Early Wynn vs Frank Lary | Fifth | 18½ out |
| Saturday, August 9 |
| » Lost to White Sox (54-53), 9-3 | Tiger Stadium (30-25) | 51-54 | |
| » Starters: Dick Donovan vs Herb Moford | Fifth | 18½ out |
| Sunday, August 10 |
| » Lost to White Sox (55-53), 5-2 | Tiger Stadium (30-26) | 51-55 | Lost 2 |
| » Starters: Ray Moore vs Paul Foytack | Fifth | 18½ out |
| » Defeated White Sox (55-54), 4-3 | Tiger Stadium (31-26) | 52-55 | |
| » Starters: Barry Latman vs Billy Hoeft | Fifth | 18½ out |
| Monday, August 11 |
| » Defeated Athletics (48-59), 3-2 | Tiger Stadium (32-26) | 53-55 | Won 2 |
| » Starters: Bob Grim vs Jim Bunning | Fourth | 17 out |
| Tuesday, August 12 |
| » Defeated Athletics (48-60), 7-6 | Tiger Stadium (33-26) | 54-55 | Won 3 |
| » Starters: Jack Urban vs Frank Lary | Fourth | 17 out |
| Wednesday, August 13 |
| » Defeated Indians (55-58), 6-2 | Cleveland Stadium (3-3) | 55-55 | Won 4 |
| » Starters: Paul Foytack vs Gary Bell | Third | 15½ out |
| » Defeated Indians (55-59), 3-2 | Cleveland Stadium (4-3) | 56-55 | Won 5 |
| » Starters: Herb Moford vs Hoyt Wilhelm | Third | 15½ out |
| Thursday, August 14 |
| » Lost to Indians (56-59), 10-9 | Cleveland Stadium (4-4) | 56-56 | |
| » Starters: George Susce vs Cal McLish | Third | 16½ out |
| Friday, August 15 |
| » Lost to Athletics (50-62), 12-5 | Municipal Stadium (1-5) | 56-57 | Lost 2 |
| » Starters: Billy Hoeft vs Ralph Terry | Fourth | 16½ out |
| Future Tiger Bob James is born in Glendale, CA. |
| Saturday, August 16 |
| » Lost to Athletics (51-62), 8-7 | Municipal Stadium (1-6) | 56-58 | Lost 3 |
| » Starters: Jim Bunning vs Jack Urban | Fourth | 16½ out |
| Sunday, August 17 |
| » Lost to Athletics (52-62), 4-1 | Municipal Stadium (1-7) | 56-59 | Lost 4 |
| » Starters: Paul Foytack vs Bob Grim | Fourth | 16½ out |
| Tuesday, August 19 |
| » Lost to Senators (51-66), 3-1 | Griffith Stadium (3-7) | 56-60 | Lost 5 |
| » Starters: Herb Moford vs Camilo Pascual | Fourth | 16½ out |
| Wednesday, August 20 |
| » Defeated Senators (51-67), 7-1 | Griffith Stadium (4-7) | 57-60 | |
| » Starters: Frank Lary vs Pedro Ramos | Fourth | 16½ out |
| Thursday, August 21 |
| » Lost to Orioles (57-61), 7-6 | Memorial Stadium (3-6) | 57-61 | |
| » Starters: Billy Hoeft vs Billy O'Dell | Fourth | 17½ out |
| Friday, August 22 |
| » Lost to Orioles (58-61), 2-1 | Memorial Stadium (3-7) | 57-62 | Lost 2 |
| » Starters: Jim Bunning vs Connie Johnson | Fifth | 18½ out |
| Saturday, August 23 |
| » Defeated Orioles (58-62), 5-1 | Memorial Stadium (4-7) | 58-62 | |
| » Starters: Paul Foytack vs Arnie Portocarrero | Fourth | 17½ out |
| Sunday, August 24 |
| » Defeated Yankees (77-47), 8-3 | Yankee Stadium (7-3) | 59-62 | Won 2 |
| » Starters: Frank Lary vs Art Ditmar | Fifth | 17½ out |
| » Lost to Yankees (78-47), 3-2 | Yankee Stadium (7-4) | 59-63 | |
| » Starters: Herb Moford vs Bobby Shantz | Fifth | 17½ out |
| Wednesday, August 27 |
| » Lost to Red Sox (64-59), 3-2 | Fenway Park (3-7) | 59-64 | Lost 2 |
| » Starters: Jim Bunning vs Tom Brewer | Fifth | 17½ out |
| » Defeated Red Sox (64-60), 7-2 | Fenway Park (4-7) | 60-64 | |
| » Starters: Paul Foytack vs Ike Delock | Fifth | 17½ out |
| Thursday, August 28 |
| Former Tiger Jean Dubuc dies in Fort Myers, FL at the age of 70. |
| Friday, August 29 |
| » Lost to White Sox (68-59), 3-0 | Comiskey Park I (3-3) | 60-65 | |
| » Starters: Herb Moford vs Dick Donovan | Fifth | 17½ out |
| Saturday, August 30 |
| » Defeated White Sox (68-60), 6-3 | Comiskey Park I (4-3) | 61-65 | |
| » Starters: Frank Lary vs Ray Moore | Fifth | 16½ out |
| Sunday, August 31 |
| » Lost to White Sox (69-60), 3-0 | Comiskey Park I (4-4) | 61-66 | |
| » Starters: Jim Bunning vs Early Wynn | Fifth | 17½ out |
| Former Tiger George Quellich dies in Johnsville, CA at the age of 53. |
| Monday, September 1 |
| » Defeated Athletics (59-70), 7-4 | Municipal Stadium (2-7) | 62-66 | |
| » Starters: Al Cicotte vs Bob Davis | Fifth | 16½ out |
| » Defeated Athletics (59-71), 5-1 | Municipal Stadium (3-7) | 63-66 | Won 2 |
| » Starters: Paul Foytack vs Jack Urban | Fifth | 16½ out |
| Tuesday, September 2 |
| » Defeated Athletics (59-72), 6-1 | Municipal Stadium (4-7) | 64-66 | Won 3 |
| » Starters: Herb Moford vs Bob Grim | Fourth | 16½ out |
| Wednesday, September 3 |
| » Lost to White Sox (70-62), 1-0 | Tiger Stadium (33-27) | 64-67 | |
| » Starters: Dick Donovan vs Frank Lary | Fifth | 17½ out |
| Thursday, September 4 |
| » Defeated White Sox (70-63), 11-4 | Tiger Stadium (34-27) | 65-67 | |
| » Starters: Ray Moore vs Jim Bunning | Fourth | 17 out |
| Former Tiger Red Killefer dies in Los Angeles, CA at the age of 74. |
| Friday, September 5 |
| » Defeated Athletics (61-73), 4-1 | Tiger Stadium (35-27) | 66-67 | Won 2 |
| » Starters: Ned Garver vs Paul Foytack | Fourth | 16 out |
| Saturday, September 6 |
| » Lost to Athletics (62-73), 6-2 | Tiger Stadium (35-28) | 66-68 | |
| » Starters: Bob Grim vs Herb Moford | Fourth | 16 out |
| Sunday, September 7 |
| » Lost to Athletics (63-73), 3-2 | Tiger Stadium (35-29) | 66-69 | Lost 2 |
| » Starters: Ray Herbert vs Frank Lary | Fourth | 16½ out |
| Tuesday, September 9 |
| » Defeated Senators (58-79), 7-1 | Tiger Stadium (36-29) | 67-69 | |
| » Starters: Hal Griggs vs Jim Bunning | Fourth | 15½ out |
| Wednesday, September 10 |
| » Lost to Senators (59-79), 5-4 | Tiger Stadium (36-30) | 67-70 | |
| » Starters: Russ Kemmerer vs Paul Foytack | Fourth | 16½ out |
| Thursday, September 11 |
| » Lost to Senators (60-79), 7-6 | Tiger Stadium (36-31) | 67-71 | Lost 2 |
| » Starters: Camilo Pascual vs Herb Moford | Fourth | 17 out |
| » Major-league debuts: George Alusik (Tigers) |
| Friday, September 12 |
| » Defeated Orioles (66-73), 3-1 | Tiger Stadium (37-31) | 68-71 | |
| » Starters: Hoyt Wilhelm vs Frank Lary | Fourth | 17 out |
| Saturday, September 13 |
| » Defeated Orioles (66-74), 13-2 | Tiger Stadium (38-31) | 69-71 | Won 2 |
| » Starters: Hal Brown vs Jim Bunning | Fourth | 17 out |
| Sunday, September 14 |
| » Defeated Red Sox (70-71), 6-1 | Tiger Stadium (39-31) | 70-71 | Won 3 |
| » Starters: Frank Sullivan vs Paul Foytack | Third | 17 out |
| » Defeated Red Sox (70-72), 9-3 | Tiger Stadium (40-31) | 71-71 | Won 4 |
| » Starters: Tom Brewer vs Billy Hoeft | Third | 17 out |
| » Major-league debuts: Jerry Casale (Red Sox) |
| Tuesday, September 16 |
| » Defeated Yankees (89-56), 4-2 | Tiger Stadium (41-31) | 72-71 | Won 5 |
| » Starters: Ryne Duren vs Frank Lary | Third | 16 out |
| » Major-league debuts: John Gabler (Yankees) |
| Wednesday, September 17 |
| » Defeated Yankees (89-57), 5-2 | Tiger Stadium (42-31) | 73-71 | Won 6 |
| » Starters: Bob Turley vs Jim Bunning | Third | 15 out |
| Thursday, September 18 |
| Future Tiger Roger Mason is born in Bellaire, MI. |
| Friday, September 19 |
| » Lost to Indians (72-73), 2-1 | Tiger Stadium (42-32) | 73-72 | |
| » Starters: Cal McLish vs Paul Foytack | Third | 15 out |
| Saturday, September 20 |
| » Lost to Indians (73-73), 2-1 | Tiger Stadium (42-33) | 73-73 | Lost 2 |
| » Starters: Don Ferrarese vs Frank Lary | Third | 14½ out |
| » Defeated Indians (73-74), 4-1 | Tiger Stadium (43-33) | 74-73 | |
| » Starters: Gary Bell vs Billy Hoeft | Third | 14½ out |
| Sunday, September 21 |
| » Lost to Indians (74-74), 3-1 | Tiger Stadium (43-34) | 74-74 | |
| » Starters: Ray Narleski vs Jim Bunning | Third | 14½ out |
| Tuesday, September 23 |
| » Defeated White Sox (79-70), 3-1 | Comiskey Park I (5-4) | 75-74 | |
| » Starters: Paul Foytack vs Early Wynn | Third | 13½ out |
| Wednesday, September 24 |
| » Lost to White Sox (80-70), 4-3 | Comiskey Park I (5-5) | 75-75 | |
| » Starters: Frank Lary vs Billy Pierce | Third | 14½ out |
| Thursday, September 25 |
| » Defeated White Sox (80-71), 7-1 | Comiskey Park I (6-5) | 76-75 | |
| » Starters: Jim Bunning vs Dick Donovan | Third | 14 out |
| Friday, September 26 |
| » Lost to Indians (76-75), 5-4 | Cleveland Stadium (4-5) | 76-76 | |
| » Starters: Billy Hoeft vs Don Ferrarese | |
