| Sunday, January 26 |
| Future Athletic Mike Patterson is born in Santa Monica, CA. |
| Monday, April 14 |
| » Major-league debuts: Albie Pearson (Senators) |
| Tuesday, April 15 |
| » Defeated Indians (0-1), 5-0 | Cleveland Stadium (1-0) | 1-0 | |
| » Starters: Ned Garver vs Herb Score | First | -- |
| » Major-league debuts: Gary Geiger Carroll Hardy and Billy Moran (Indians) |
| Wednesday, April 16 |
| » Defeated Indians (0-2), 9-4 | Cleveland Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Ralph Terry vs Ray Narleski | First | -- |
| Thursday, April 17 |
| » Lost to Indians (1-2), 3-2 | Cleveland Stadium (2-1) | 2-1 | |
| » Starters: Duke Maas vs Mudcat Grant | Second | ½ out |
| » Major-league debuts: Mudcat Grant (Indians) |
| Friday, April 18 |
| » Lost to White Sox (2-2), 11-7 | Municipal Stadium (0-1) | 2-2 | Lost 2 |
| » Starters: Jim Wilson vs Alex Kellner | Third | 1 out |
| Sunday, April 20 |
| » Defeated White Sox (2-3), 8-2 | Municipal Stadium (1-1) | 3-2 | |
| » Starters: Bill Fischer vs Jack Urban | Second | 1½ out |
| Monday, April 21 |
| » Defeated Indians (3-4), 9-4 | Municipal Stadium (2-1) | 4-2 | Won 2 |
| » Starters: Mudcat Grant vs Ralph Terry | Second | 1½ out |
| Tuesday, April 22 |
| » Defeated Indians (3-5), 9-6 | Municipal Stadium (3-1) | 5-2 | Won 3 |
| » Starters: Bob Lemon vs Ned Garver | Second | 1½ out |
| Wednesday, April 23 |
| » Lost to Tigers (6-3), 8-2 | Municipal Stadium (3-2) | 5-3 | |
| » Starters: Paul Foytack vs Duke Maas | Third | 1½ out |
| Thursday, April 24 |
| » Defeated Tigers (6-4), 7-2 | Municipal Stadium (4-2) | 6-3 | |
| » Starters: Bob Shaw vs Wally Burnette | Second | 1 out |
| Future Athletic Bill Krueger is born in Waukegan, IL. |
| Friday, April 25 |
| » Lost to White Sox (3-7), 6-5 | Comiskey Park I (0-1) | 6-4 | |
| » Starters: Alex Kellner vs Early Wynn | Third | 1 out |
| Saturday, April 26 |
| » Defeated White Sox (3-8), 7-1 | Comiskey Park I (1-1) | 7-4 | |
| » Starters: Ralph Terry vs Dick Donovan | Third | 1 out |
| Wednesday, April 30 |
| » Defeated Red Sox (4-10), 11-4 | Fenway Park (1-0) | 8-4 | Won 2 |
| » Starters: Ned Garver vs Tom Brewer | Second | ½ out |
| Thursday, May 1 |
| » Lost to Red Sox (5-10), 7-6 | Fenway Park (1-1) | 8-5 | |
| » Starters: Wally Burnette vs Mike Fornieles | Second | 1 out |
| Friday, May 2 |
| » Lost to Yankees (10-4), 8-1 | Yankee Stadium (0-1) | 8-6 | Lost 2 |
| » Starters: Ralph Terry vs Bob Turley | Third | 2 out |
| Sunday, May 4 |
| » Lost to Senators (9-5), 7-3 | Griffith Stadium (0-1) | 8-7 | Lost 3 |
| » Starters: Alex Kellner vs Pedro Ramos | Third | 2½ out |
| » Tied Senators, 2-2 | Griffith Stadium (0-1) | 8-7 | |
| » Starters: Jack Urban vs Russ Kemmerer | Third | 2½ out |
| Friday, May 9 |
| » Lost to Tigers (10-12), 7-1 | Tiger Stadium (0-1) | 8-8 | Lost 4 |
| » Starters: Ned Garver vs Paul Foytack | Third | 3½ out |
| Saturday, May 10 |
| » Lost to Tigers (11-12), 3-2 | Tiger Stadium (0-2) | 8-9 | Lost 5 |
| » Starters: Ralph Terry vs Billy Hoeft | Fifth | 4½ out |
| Sunday, May 11 |
| » Lost to Tigers (12-12), 10-3 | Tiger Stadium (0-3) | 8-10 | Lost 6 |
| » Starters: Jack Urban vs Jim Bunning | Sixth | 5 out |
| Monday, May 12 |
| » Defeated White Sox (7-13), 2-1 | Municipal Stadium (5-2) | 9-10 | |
| » Starters: Ray Moore vs Alex Kellner | Fifth | 4½ out |
| Tuesday, May 13 |
| » Lost to White Sox (8-13), 9-2 | Municipal Stadium (5-3) | 9-11 | |
| » Starters: Early Wynn vs Wally Burnette | Fifth | 5½ out |
| Wednesday, May 14 |
| » Lost to White Sox (9-13), 4-1 | Municipal Stadium (5-4) | 9-12 | Lost 2 |
| » Starters: Dick Donovan vs Duke Maas | Seventh | 6½ out |
| Thursday, May 15 |
| » Defeated White Sox (9-14), 3-0 | Municipal Stadium (6-4) | 10-12 | |
| » Starters: Jim Wilson vs Ned Garver | Fifth | 6 out |
| Friday, May 16 |
| » Defeated Tigers (13-15), 5-3 | Municipal Stadium (7-4) | 11-12 | Won 2 |
| » Starters: Herm Wehmeier vs Ralph Terry | Fourth | 6 out |
| Saturday, May 17 |
| » Defeated Tigers (13-16), 4-3 | Municipal Stadium (8-4) | 12-12 | Won 3 |
| » Starters: Frank Lary vs Jack Urban | Second | 6 out |
| Sunday, May 18 |
| » Defeated Tigers (13-17), 2-0 | Municipal Stadium (9-4) | 13-12 | Won 4 |
| » Starters: Paul Foytack vs Duke Maas | Second | 6½ out |
| Tuesday, May 20 |
| » Defeated Senators (13-16), 7-3 | Municipal Stadium (10-4) | 14-12 | Won 5 |
| » Starters: Hal Griggs vs Ned Garver | Second | 6½ out |
| Wednesday, May 21 |
| » Lost to Senators (14-16), 6-1 | Municipal Stadium (10-5) | 14-13 | |
| » Starters: Russ Kemmerer vs Ralph Terry | Second | 7½ out |
| Thursday, May 22 |
| » Lost to Red Sox (16-17), 8-5 | Municipal Stadium (10-6) | 14-14 | Lost 2 |
| » Starters: Tom Brewer vs Jack Urban | Second | 8½ out |
| Friday, May 23 |
| » Lost to Red Sox (17-17), 9-1 | Municipal Stadium (10-7) | 14-15 | Lost 3 |
| » Starters: Willard Nixon vs Duke Maas | Fourth | 9½ out |
| Saturday, May 24 |
| » Lost to Red Sox (18-17), 5-4 | Municipal Stadium (10-8) | 14-16 | Lost 4 |
| » Starters: Frank Sullivan vs Alex Kellner | Fourth | 9½ out |
| Sunday, May 25 |
| » Defeated Orioles (14-17), 4-0 | Municipal Stadium (11-8) | 15-16 | |
| » Starters: Milt Pappas vs Ned Garver | Third | 10 out |
| Monday, May 26 |
| » Defeated Orioles (14-18), 5-4 | Municipal Stadium (12-8) | 16-16 | Won 2 |
| » Starters: Connie Johnson vs Ralph Terry | Third | 9½ out |
| Tuesday, May 27 |
| » Defeated Yankees (25-7), 7-3 | Municipal Stadium (13-8) | 17-16 | Won 3 |
| » Starters: Bob Turley vs Jack Urban | Second | 8½ out |
| Wednesday, May 28 |
| » Defeated Yankees (25-8), 4-3 | Municipal Stadium (14-8) | 18-16 | Won 4 |
| » Starters: Tom Sturdivant vs Ray Herbert | Second | 7½ out |
| Friday, May 30 |
| » Lost to Indians (21-20), 7-1 | Municipal Stadium (14-9) | 18-17 | |
| » Starters: Ray Narleski vs Ralph Terry | Second | 6½ out |
| » Defeated Indians (21-21), 7-6 | Municipal Stadium (15-9) | 19-17 | |
| » Starters: Dick Tomanek vs Ned Garver | Second | 6½ out |
| Saturday, May 31 |
| » Defeated Indians (21-22), 5-4 | Municipal Stadium (16-9) | 20-17 | Won 2 |
| » Starters: Mudcat Grant vs Jack Urban | Second | 6½ out |
| Sunday, June 1 |
| » Defeated Indians (21-23), 6-2 | Municipal Stadium (17-9) | 21-17 | Won 3 |
| » Starters: Cal McLish vs Ray Herbert | Second | 6½ out |
| » Major-league debuts: Gary Bell (Indians) |
| Tuesday, June 3 |
| » Lost to Senators (20-23), 5-4 | Griffith Stadium (0-2) | 21-18 | |
| » Starters: Ralph Terry vs Russ Kemmerer | Second | 8½ out |
| » Lost to Senators (21-23), 10-9 | Griffith Stadium (0-3) | 21-19 | Lost 2 |
| » Starters: Ned Garver vs Pedro Ramos | Second | 8½ out |
| Wednesday, June 4 |
| » Defeated Senators (21-24), 5-4 | Griffith Stadium (1-3) | 22-19 | |
| » Starters: Jack Urban vs Al Cicotte | Second | 7½ out |
| Thursday, June 5 |
| » Defeated Senators (21-25), 2-0 | Griffith Stadium (2-3) | 23-19 | Won 2 |
| » Starters: Ralph Terry vs Camilo Pascual | Second | 7 out |
| Friday, June 6 |
| » Lost to Orioles (19-24), 2-1 | Memorial Stadium (0-1) | 23-20 | |
| » Starters: Alex Kellner vs Connie Johnson | Second | 8½ out |
| » Lost to Orioles (20-24), 3-1 | Memorial Stadium (0-2) | 23-21 | Lost 2 |
| » Starters: Ray Herbert vs Milt Pappas | Second | 8½ out |
| Saturday, June 7 |
| » Defeated Orioles (20-25), 5-2 | Memorial Stadium (1-2) | 24-21 | |
| » Starters: Murry Dickson vs Jack Harshman | Second | 8½ out |
| Sunday, June 8 |
| » Lost to Orioles (21-25), 4-0 | Memorial Stadium (1-3) | 24-22 | |
| » Starters: Ned Garver vs Hal Brown | Second | 7½ out |
| » Defeated Orioles (21-26), 2-1 | Memorial Stadium (2-3) | 25-22 | |
| » Starters: Duke Maas vs Arnie Portocarrero | Second | 7½ out |
| Wednesday, June 11 |
| » Lost to Yankees (33-14), 10-2 | Yankee Stadium (0-2) | 25-23 | |
| » Starters: Jack Urban vs Don Larsen | Second | 9½ out |
| » Lost to Yankees (34-14), 2-1 | Yankee Stadium (0-3) | 25-24 | Lost 2 |
| » Starters: Ralph Terry vs Bob Turley | Second | 9½ out |
| Thursday, June 12 |
| » Defeated Yankees (34-15), 4-1 | Yankee Stadium (1-3) | 26-24 | |
| » Starters: Ray Herbert vs Tom Sturdivant | Third | 9½ out |
| » Lost to Yankees (35-15), 3-2 | Yankee Stadium (1-4) | 26-25 | |
| » Starters: Murry Dickson vs Whitey Ford | Third | 9½ out |
| Friday, June 13 |
| » Lost to Red Sox (29-26), 9-3 | Fenway Park (1-2) | 26-26 | Lost 2 |
| » Starters: Ned Garver vs Tom Brewer | Third | 9½ out |
| Saturday, June 14 |
| » Lost to Red Sox (30-26), 7-1 | Fenway Park (1-3) | 26-27 | Lost 3 |
| » Starters: Jack Urban vs Frank Sullivan | Third | 9½ out |
| Sunday, June 15 |
| » Defeated Red Sox (30-27), 17-6 | Fenway Park (2-3) | 27-27 | |
| » Starters: Ralph Terry vs Willard Nixon | Third | 7½ out |
| » Defeated Red Sox (30-28), 9-4 | Fenway Park (3-3) | 28-27 | Won 2 |
| » Starters: Duke Maas vs Mike Fornieles | Third | 7½ out |
| Tuesday, June 17 |
| » Lost to Orioles (25-30), 4-1 | Municipal Stadium (17-10) | 28-28 | |
| » Starters: Billy O'Dell vs Ray Herbert | Third | 8½ out |
| Wednesday, June 18 |
| » Lost to Orioles (26-30), 5-3 | Municipal Stadium (17-11) | 28-29 | Lost 2 |
| » Starters: Milt Pappas vs Murry Dickson | Third | 9½ out |
| Thursday, June 19 |
| » Lost to Orioles (27-30), 4-2 | Municipal Stadium (17-12) | 28-30 | Lost 3 |
| » Starters: Hal Brown vs Ned Garver | Third | 10½ out |
| Friday, June 20 |
| » Defeated Red Sox (31-31), 5-3 | Municipal Stadium (18-12) | 29-30 | |
| » Starters: Bob Smith vs Ralph Terry | Third | 9½ out |
| Saturday, June 21 |
| » Defeated Red Sox (31-32), 8-5 | Municipal Stadium (19-12) | 30-30 | Won 2 |
| » Starters: Dave Sisler vs Ray Herbert | Second | 8½ out |
| Sunday, June 22 |
| » Defeated Red Sox (31-33), 2-1 | Municipal Stadium (20-12) | 31-30 | Won 3 |
| » Starters: Tom Brewer vs Jack Urban | Second | 8½ out |
| Monday, June 23 |
| » Defeated Senators (28-35), 7-2 | Municipal Stadium (21-12) | 32-30 | Won 4 |
| » Starters: Russ Kemmerer vs Murry Dickson | Second | 7½ out |
| Tuesday, June 24 |
| » Tied Senators, 2-2 | Municipal Stadium (21-12) | 32-30 | |
| » Starters: Tex Clevenger vs Ralph Terry | Second | 8 out |
| Wednesday, June 25 |
| » Defeated Senators (28-36), 4-3 | Municipal Stadium (22-12) | 33-30 | Won 5 |
| » Starters: Pedro Ramos vs Ned Garver | Second | 7½ out |
| Thursday, June 26 |
| » Defeated Senators (28-37), 8-6 | Municipal Stadium (23-12) | 34-30 | Won 6 |
| » Starters: Hal Griggs vs Wally Burnette | Second | 7½ out |
| Friday, June 27 |
| » Lost to Yankees (42-22), 10-3 | Municipal Stadium (23-13) | 34-31 | |
| » Starters: Duke Maas vs Ray Herbert | Second | 8½ out |
| Saturday, June 28 |
| » Lost to Yankees (43-22), 8-0 | Municipal Stadium (23-14) | 34-32 | Lost 2 |
| » Starters: Whitey Ford vs Jack Urban | Second | 9½ out |
| Sunday, June 29 |
| » Defeated Yankees (43-23), 12-6 | Municipal Stadium (24-14) | 35-32 | |
| » Starters: Bob Turley vs Ralph Terry | Second | 8½ out |
| Monday, June 30 |
| » Lost to Tigers (34-34), 7-6 | Tiger Stadium (0-4) | 35-33 | |
| » Starters: Jack Urban vs George Susce | Second | 9 out |
| Tuesday, July 1 |
| » Defeated Tigers (34-35), 5-1 | Tiger Stadium (1-4) | 36-33 | |
| » Starters: Ned Garver vs Frank Lary | Second | 8½ out |
| Wednesday, July 2 |
| » Lost to Tigers (35-35), 5-0 | Tiger Stadium (1-5) | 36-34 | |
| » Starters: Ralph Terry vs Jim Bunning | Second | 9½ out |
| Thursday, July 3 |
| » Lost to White Sox (35-36), 7-2 | Comiskey Park I (1-2) | 36-35 | Lost 2 |
| » Starters: Ray Herbert vs Jim Wilson | Second | 10½ out |
| Friday, July 4 |
| » Defeated White Sox (35-37), 6-5 | Comiskey Park I (2-2) | 37-35 | |
| » Starters: Murry Dickson vs Early Wynn | Second | 10½ out |
| » Defeated White Sox (35-38), 4-3 | Comiskey Park I (3-2) | 38-35 | Won 2 |
| » Starters: Bud Daley vs Ray Moore | Second | 10½ out |
| Saturday, July 5 |
| » Lost to Indians (36-40), 8-2 | Cleveland Stadium (2-2) | 38-36 | |
| » Starters: Ralph Terry vs Ray Narleski | Second | 11 out |
| Sunday, July 6 |
| » Lost to Indians (37-40), 8-5 | Cleveland Stadium (2-3) | 38-37 | Lost 2 |
| » Starters: Ned Garver vs Gary Bell | Second | 11 out |
| Thursday, July 10 |
| » Lost to Orioles (36-40), 6-3 | Memorial Stadium (2-4) | 38-38 | Lost 3 |
| » Starters: Bud Daley vs Milt Pappas | Third | 12½ out |
| » Lost to Orioles (37-40), 3-2 | Memorial Stadium (2-5) | 38-39 | Lost 4 |
| » Starters: Ray Herbert vs Arnie Portocarrero | Third | 12½ out |
| Sunday, July 13 |
| » Lost to Senators (34-46), 2-0 | Griffith Stadium (2-4) | 38-40 | Lost 5 |
| » Starters: Ralph Terry vs Camilo Pascual | Fourth | 14½ out |
| » Lost to Senators (35-46), 4-2 | Griffith Stadium (2-5) | 38-41 | Lost 6 |
| » Starters: Ned Garver vs John Romonosky | Fourth | 14½ out |
| Monday, July 14 |
| » Defeated Senators (35-47), 4-0 | Griffith Stadium (3-5) | 39-41 | |
| » Starters: Jack Urban vs Pedro Ramos | Fourth | 14½ out |
| Tuesday, July 15 |
| » Lost to Red Sox (42-40), 5-2 | Fenway Park (3-4) | 39-42 | |
| » Starters: Ray Herbert vs Frank Sullivan | Fourth | 14½ out |
| Wednesday, July 16 |
| » Lost to Red Sox (43-40), 5-2 | Fenway Park (3-5) | 39-43 | Lost 2 |
| » Starters: Murry Dickson vs Ike Delock | Fifth | 15½ out |
| Thursday, July 17 |
| » Lost to Red Sox (44-40), 6-2 | Fenway Park (3-6) | 39-44 | Lost 3 |
| » Starters: Tom Gorman vs Tom Brewer | Fifth | 16½ out |
| Friday, July 18 |
| » Defeated Yankees (56-29), 2-1 | Yankee Stadium (2-4) | 40-44 | |
| » Starters: Dick Tomanek vs Don Larsen | Fifth | 15½ out |
| Saturday, July 19 |
| » Defeated Yankees (56-30), 6-4 | Yankee Stadium (3-4) | 41-44 | Won 2 |
| » Starters: Bob Grim vs Duke Maas | Fourth | 14½ out |
| Sunday, July 20 |
| » Lost to Yankees (57-30), 3-1 | Yankee Stadium (3-5) | 41-45 | |
| » Starters: Ned Garver vs Tom Sturdivant | Sixth | 16½ out |
| » Lost to Yankees (58-30), 8-0 | Yankee Stadium (3-6) | 41-46 | Lost 2 |
| » Starters: Jack Urban vs Whitey Ford | Sixth | 16½ out |
| Tuesday, July 22 |
| » Defeated Red Sox (47-42), 4-3 | Municipal Stadium (25-14) | 42-46 | |
| » Starters: Tom Brewer vs Murry Dickson | Fifth | 16½ out |
| Wednesday, July 23 |
| » Defeated Red Sox (47-43), 3-1 | Municipal Stadium (26-14) | 43-46 | Won 2 |
| » Starters: Bill Monbouquette vs Ralph Terry | Fourth | 16½ out |
| Friday, July 25 |
| » Lost to Orioles (46-45), 8-3 | Municipal Stadium (26-15) | 43-47 | |
| » Starters: Arnie Portocarrero vs Bob Grim | Fifth | 18 out |
| Saturday, July 26 |
| » Lost to Orioles (47-45), 4-3 | Municipal Stadium (26-16) | 43-48 | Lost 2 |
| » Starters: Jack Harshman vs Bob Davis | Fourth | 19 out |
| » Major-league debuts: Bob Davis (Athletics) |
| Sunday, July 27 |
| » Defeated Orioles (47-46), 11-6 | Municipal Stadium (27-16) | 44-48 | |
| » Starters: Hal Brown vs Ned Garver | Fifth | 17½ out |
| Monday, July 28 |
| » Lost to Yankees (64-32), 14-7 | Municipal Stadium (27-17) | 44-49 | |
| » Starters: Zach Monroe vs Dick Tomanek | Fifth | 18½ out |
| Tuesday, July 29 |
| » Defeated Yankees (64-33), 7-3 | Municipal Stadium (28-17) | 45-49 | |
| » Starters: Whitey Ford vs Ralph Terry | Fifth | 17½ out |
| Wednesday, July 30 |
| » Defeated Yankees (64-34), 2-0 | Municipal Stadium (29-17) | 46-49 | Won 2 |
| » Starters: Don Larsen vs Bob Grim | Fifth | 16½ out |
| Thursday, July 31 |
| » Lost to Yankees (65-34), 8-3 | Municipal Stadium (29-18) | 46-50 | |
| » Starters: Duke Maas vs Jack Urban | Sixth | 17½ out |
| Friday, August 1 |
| » Lost to Senators (43-58), 10-4 | Municipal Stadium (29-19) | 46-51 | Lost 2 |
| » Starters: Pedro Ramos vs Bob Davis | Seventh | 18½ out |
| Saturday, August 2 |
| » Lost to Senators (44-58), 6-3 | Municipal Stadium (29-20) | 46-52 | Lost 3 |
| » Starters: Camilo Pascual vs Ned Garver | Seventh | 19½ out |
| Sunday, August 3 |
| » Defeated Senators (44-59), 12-0 | Municipal Stadium (30-20) | 47-52 | |
| » Starters: Russ Kemmerer vs Ralph Terry | Seventh | 18½ out |
| » Lost to Senators (45-59), 4-3 | Municipal Stadium (30-21) | 47-53 | |
| » Starters: Hal Griggs vs Jack Urban | Seventh | 18½ out |
| Tuesday, August 5 |
| » Lost to White Sox (52-52), 5-4 | Municipal Stadium (30-22) | 47-54 | Lost 2 |
| » Starters: Jim Wilson vs Bob Grim | Sixth | 20 out |
| Wednesday, August 6 |
| » Lost to White Sox (53-52), 4-2 | Municipal Stadium (30-23) | 47-55 | Lost 3 |
| » Starters: Billy Pierce vs Bob Davis | Sixth | 21 out |
| Friday, August 8 |
| » Lost to Indians (53-54), 10-4 | Cleveland Stadium (2-4) | 47-56 | Lost 4 |
| » Starters: Ned Garver vs Mudcat Grant | Sixth | 22 out |
| Saturday, August 9 |
| » Lost to Indians (54-54), 3-1 | Cleveland Stadium (2-5) | 47-57 | Lost 5 |
| » Starters: Ralph Terry vs Gary Bell | Seventh | 22 out |
| Future Athletic Matt Young is born in Pasadena, CA. |
| Sunday, August 10 |
| » Lost to Indians (55-54), 11-2 | Cleveland Stadium (2-6) | 47-58 | Lost 6 |
| » Starters: Jack Urban vs Cal McLish | Seventh | 22 out |
| » Defeated Indians (55-55), 4-2 | Cleveland Stadium (3-6) | 48-58 | |
| » Starters: Bud Daley vs Hal Woodeshick | Seventh | 22 out |
| Monday, August 11 |
| » Lost to Tigers (53-55), 3-2 | Tiger Stadium (1-6) | 48-59 | |
| » Starters: Bob Grim vs Jim Bunning | Sixth | 21½ out |
| Tuesday, August 12 |
| » Lost to Tigers (54-55), 7-6 | Tiger Stadium (1-7) | 48-60 | Lost 2 |
| » Starters: Jack Urban vs Frank Lary | Seventh | 22½ out |
| Wednesday, August 13 |
| » Defeated White Sox (57-55), 2-1 | Comiskey Park I (4-2) | 49-60 | |
| » Starters: Ned Garver vs Dick Donovan | Sixth | 22 out |
| » Lost to White Sox (58-55), 6-5 | Comiskey Park I (4-3) | 49-61 | |
| » Starters: Murry Dickson vs Jim Wilson | Sixth | 22 out |
| Thursday, August 14 |
| » Lost to White Sox (59-55), 5-2 | Comiskey Park I (4-4) | 49-62 | Lost 2 |
| » Starters: Bud Daley vs Ray Moore | Sixth | 23 out |
| Friday, August 15 |
| » Defeated Tigers (56-57), 12-5 | Municipal Stadium (31-23) | 50-62 | |
| » Starters: Billy Hoeft vs Ralph Terry | Seventh | 22 out |
| Saturday, August 16 |
| » Defeated Tigers (56-58), 8-7 | Municipal Stadium (32-23) | 51-62 | Won 2 |
| » Starters: Jim Bunning vs Jack Urban | Seventh | 21 out |
| Sunday, August 17 |
| » Defeated Tigers (56-59), 4-1 | Municipal Stadium (33-23) | 52-62 | Won 3 |
| » Starters: Paul Foytack vs Bob Grim | Seventh | 20 out |
| Monday, August 18 |
| » Lost to Orioles (55-59), 8-2 | Memorial Stadium (2-6) | 52-63 | |
| » Starters: Ralph Terry vs Hal Brown | Seventh | 20½ out |
| Tuesday, August 19 |
| » Defeated Orioles (55-60), 4-1 | Memorial Stadium (3-6) | 53-63 | |
| » Starters: Ned Garver vs Milt Pappas | Seventh | 19 out |
| » Defeated Orioles (55-61), 6-4 | Memorial Stadium (4-6) | 54-63 | Won 2 |
| » Starters: Murry Dickson vs Arnie Portocarrero | Seventh | 19 out |
| Wednesday, August 20 |
| » Lost to Orioles (56-61), 4-3 | Memorial Stadium (4-7) | 54-64 | |
| » Starters: Walt Craddock vs Jack Harshman | Seventh | 20 out |
| Thursday, August 21 |
| » Defeated Senators (51-68), 7-4 | Griffith Stadium (4-5) | 55-64 | |
| » Starters: Jack Urban vs Vito Valentinetti | Sixth | 20 out |
| Friday, August 22 |
| » Defeated Senators (51-69), 1-0 | Griffith Stadium (5-5) | 56-64 | Won 2 |
| » Starters: Ralph Terry vs Russ Kemmerer | Sixth | 20 out |
| Saturday, August 23 |
| » Defeated Senators (51-70), 3-1 | Griffith Stadium (6-5) | 57-64 | Won 3 |
| » Starters: Bob Grim vs Camilo Pascual | Sixth | 19 out |
| Sunday, August 24 |
| » Lost to Red Sox (62-59), 14-3 | Fenway Park (3-7) | 57-65 | |
| » Starters: Ned Garver vs Frank Sullivan | Seventh | 20 out |
| » Lost to Red Sox (63-59), 3-2 | Fenway Park (3-8) | 57-66 | Lost 2 |
| » Starters: Ray Herbert vs Ted Bowsfield | Seventh | 20 out |
| Tuesday, August 26 |
| » Lost to Yankees (79-47), 6-2 | Yankee Stadium (3-7) | 57-67 | Lost 3 |
| » Starters: Jack Urban vs Bob Turley | Seventh | 21 out |
| Wednesday, August 27 |
| » Defeated Yankees (79-48), 11-7 | Yankee Stadium (4-7) | 58-67 | |
| » Starters: Ralph Terry vs Johnny Kucks | Seventh | 20 out |
| Friday, August 29 |
| » Defeated Indians (60-68), 8-7 | Municipal Stadium (34-23) | 59-67 | Won 2 |
| » Starters: Hal Woodeshick vs Bob Grim | Seventh | 19 out |
| Saturday, August 30 |
| » Lost to Indians (61-68), 8-6 | Municipal Stadium (34-24) | 59-68 | |
| » Starters: Mudcat Grant vs Ned Garver | Seventh | 19 out |
| Sunday, August 31 |
| » Lost to Indians (62-68), 3-2 | Municipal Stadium (34-25) | 59-69 | Lost 2 |
| » Starters: Cal McLish vs Ralph Terry | Seventh | 20 out |
| Monday, September 1 |
| » Lost to Tigers (62-66), 7-4 | Municipal Stadium (34-26) | 59-70 | Lost 3 |
| » Starters: Al Cicotte vs Bob Davis | Seventh | 21 out |
| » Lost to Tigers (63-66), 5-1 | Municipal Stadium (34-27) | 59-71 | Lost 4 |
| » Starters: Paul Foytack vs Jack Urban | Seventh | 21 out |
| Tuesday, September 2 |
| » Lost to Tigers (64-66), 6-1 | Municipal Stadium (34-28) | 59-72 | Lost 5 |
| » Starters: Herb Moford vs Bob Grim | Sixth | 22 out |
| Wednesday, September 3 |
| » Defeated Indians (64-69), 6-2 | Cleveland Stadium (4-6) | 60-72 | |
| » Starters: Ray Herbert vs Hal Woodeshick | Seventh | 22 out |
| Thursday, September 4 |
| » Defeated Indians (64-70), 2-1 | Cleveland Stadium (5-6) | 61-72 | Won 2 |
| » Starters: Ralph Terry vs Cal McLish | Sixth | 21½ out |
| Friday, September 5 |
| » Lost to Tigers (66-67), 4-1 | Tiger Stadium (1-8) | 61-73 | |
| » Starters: Ned Garver vs Paul Foytack | Seventh | 21½ out |
| Saturday, September 6 |
| » Defeated Tigers (66-68), 6-2 | Tiger Stadium (2-8) | 62-73 | |
| » Starters: Bob Grim vs Herb Moford | Sixth | 20½ out |
| Sunday, September 7 |
| » Defeated Tigers (66-69), 3-2 | Tiger Stadium (3-8) | 63-73 | Won 2 |
| » Starters: Ray Herbert vs Frank Lary | Sixth | 20 out |
| Tuesday, September 9 |
| » Defeated Orioles (66-70), 8-6 | Municipal Stadium (35-28) | 64-73 | Won 3 |
| » Starters: Arnie Portocarrero vs Ralph Terry | Seventh | 19 out |
| » Major-league debuts: Willie Tasby (Orioles) |
| Wednesday, September 10 |
| » Defeated Orioles (66-71), 4-2 | Municipal Stadium (36-28) | 65-73 | Won 4 |
| » Starters: Jack Harshman vs Bob Grim | Seventh | 19 out |
| Former Athletic Arlas Taylor dies in Dade City, FL at the age of 63. |
| Thursday, September 11 |
| » Defeated Orioles (66-72), 7-1 | Municipal Stadium (37-28) | 66-73 | Won 5 |
| » Starters: Billy O'Dell vs Ned Garver | Seventh | 18½ out |
| Friday, September 12 |
| » Defeated Senators (60-80), 4-3 | Municipal Stadium (38-28) | 67-73 | Won 6 |
| » Starters: Pedro Ramos vs Ray Herbert | Sixth | 18½ out |
| Saturday, September 13 |
| » Lost to Senators (61-80), 8-5 | Municipal Stadium (38-29) | 67-74 | |
| » Starters: Vito Valentinetti vs Jack Urban | Sixth | 19½ out |
| Sunday, September 14 |
| » Lost to Yankees (88-55), 5-3 | Municipal Stadium (38-30) | 67-75 | Lost 2 |
| » Starters: Duke Maas vs Ralph Terry | Seventh | 21½ out |
| » Lost to Yankees (89-55), 12-7 | Municipal Stadium (38-31) | 67-76 | Lost 3 |
| » Starters: Whitey Ford vs Bob Grim | Seventh | 21½ out |
| Tuesday, September 16 |
| » Major-league debuts: Bob Allison (Senators) |
| Wednesday, September 17 |
| » Defeated Red Sox (70-73), 6-3 | Municipal Stadium (39-31) | 68-76 | |
| » Starters: Ike Delock vs Ray Herbert | Sixth | 20½ out |
| » Lost to Red Sox (71-73), 4-2 | Municipal Stadium (39-32) | 68-77 | |
| » Starters: Bill Monbouquette vs Ned Garver | Sixth | 20½ out |
| Thursday, September 18 |
| » Defeated Red Sox (71-74), 4-1 | Municipal Stadium (40-32) | 69-77 | |
| » Starters: Ted Bowsfield vs Bud Daley | Sixth | 20 out |
| Friday, September 19 |
| » Defeated White Sox (78-68), 7-6 | Municipal Stadium (41-32) | 70-77 | Won 2 |
| » Starters: Early Wynn vs Ralph Terry | Sixth | 19 out |
| Saturday, September 20 |
| » Defeated White Sox (78-69), 3-2 | Municipal Stadium (42-32) | 71-77 | Won 3 |
| » Starters: Billy Pierce vs Bob Grim | Fifth | 18 out |
| Sunday, September 21 |
| » Lost to White Sox (79-69), 2-1 | Municipal Stadium (42-33) | 71-78 | |
| » Starters: Dick Donovan vs Ray Herbert | Fourth | 18 out |
| Tuesday, September 23 |
| » Lost to Indians (75-74), 7-5 | Municipal Stadium (42-34) | 71-79 | Lost 2 |
| » Starters: Cal McLish vs Ned Garver | Fifth | 18 out |
| Wednesday, September 24 |
| » Defeated Indians (75-75), 7-4 | Municipal Stadium (43-34) | 72-79 | |
| » Starters: Gary Bell vs Ralph Terry | Fifth | 18 out |
| Friday, September 26 |
| » Lost to White Sox (81-71), 1-0 | Comiskey Park I (4-5) | 72-80 | |
| » Starters: Bob Grim vs Barry Latman | Seventh | 18 out |
| Saturday, September 27 |
| » Defeated White Sox (81-72), 2-1 | Comiskey Park I (5-5) | 73-80 | |
| » Starters: Howie Reed vs Early Wynn | Seventh | 17½ out |
| Sunday, September 28 |
| » Lost to White Sox (82-72), 11-4 | Comiskey Park I (5-6) | 73-81 | |
| » Starters: John Tsitouris vs Stover McIlwain | Seventh | 19 out |
| » Major-league debuts: Chuck Lindstrom (White Sox) |
| Sunday, November 2 |
| Future Athletic Willie McGee is born in San Francisco, CA. |
| Thursday, December 25 |
| Future Athletic Rickey Henderson is born in Chicago, IL. |
Game information provided by Retrosheet (www.retrosheet.org) |
