| Monday, April 15 |
| » Defeated Senators (0-1), 7-6 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Hal Brown vs Bob Chakales | First | -- |
| » Major-league debuts: Neil Chrisley (Senators) |
| Tuesday, April 16 |
| » Lost to Red Sox (1-0), 4-2 | Memorial Stadium (0-1) | 1-1 | |
| » Starters: Tom Brewer vs Bill Wight | Second | ½ out |
| Thursday, April 18 |
| » Lost to Senators (1-2), 6-4 | Griffith Stadium (1-1) | 1-2 | Lost 2 |
| » Starters: Ray Moore vs Ted Abernathy | Fourth | 1½ out |
| Saturday, April 20 |
| » Lost to Senators (2-2), 6-4 | Griffith Stadium (1-2) | 1-3 | Lost 3 |
| » Starters: Connie Johnson vs Camilo Pascual | Fourth | 2½ out |
| Sunday, April 21 |
| » Defeated Senators (2-3), 11-9 | Griffith Stadium (2-2) | 2-3 | |
| » Starters: Charlie Beamon vs Bob Chakales | Sixth | 3 out |
| » Lost to Senators (3-3), 3-2 | Griffith Stadium (2-3) | 2-4 | |
| » Starters: Hal Brown vs Evelio Hernandez | Sixth | 3 out |
| Future Oriole Jesse Orosco is born in Santa Barbara, CA. |
| Monday, April 22 |
| » Defeated Red Sox (2-3), 7-5 | Fenway Park (1-0) | 3-4 | |
| » Starters: Ray Moore vs Tom Brewer | Fourth | 2½ out |
| Future Oriole Dave Schmidt is born in Niles, MI. |
| Tuesday, April 23 |
| » Lost to Red Sox (3-3), 3-1 | Fenway Park (1-1) | 3-5 | |
| » Starters: Billy Loes vs Frank Sullivan | Seventh | 2½ out |
| Wednesday, April 24 |
| » Lost to Yankees (5-2), 3-2 | Yankee Stadium (0-1) | 3-6 | Lost 2 |
| » Starters: Connie Johnson vs Art Ditmar | Seventh | 3 out |
| Friday, April 26 |
| » Defeated Senators (4-7), 4-3 | Memorial Stadium (1-1) | 4-6 | |
| » Starters: Camilo Pascual vs Ray Moore | Fifth | 3½ out |
| Saturday, April 27 |
| » Defeated Senators (4-8), 4-0 | Memorial Stadium (2-1) | 5-6 | Won 2 |
| » Starters: Chuck Stobbs vs Mike Fornieles | Fifth | 2½ out |
| Sunday, April 28 |
| » Lost to Senators (5-8), 7-6 | Memorial Stadium (2-2) | 5-7 | |
| » Starters: Garland Shifflett vs Don Ferrarese | Fifth | 3 out |
| » Defeated Senators (5-9), 3-2 | Memorial Stadium (3-2) | 6-7 | |
| » Starters: Ted Abernathy vs Hal Brown | Fifth | 3 out |
| Tuesday, April 30 |
| » Lost to White Sox (8-2), 6-1 | Comiskey Park I (0-1) | 6-8 | |
| » Starters: Ray Moore vs Billy Pierce | Sixth | 4 out |
| Wednesday, May 1 |
| » Lost to White Sox (9-2), 9-3 | Comiskey Park I (0-2) | 6-9 | Lost 2 |
| » Starters: Billy Loes vs Jack Harshman | Sixth | 5 out |
| Saturday, May 4 |
| » Lost to Tigers (8-9), 3-0 | Tiger Stadium (0-1) | 6-10 | Lost 3 |
| » Starters: Mike Fornieles vs Duke Maas | Sixth | 6 out |
| Sunday, May 5 |
| » Lost to Tigers (9-9), 3-1 | Tiger Stadium (0-2) | 6-11 | Lost 4 |
| » Starters: Connie Johnson vs Frank Lary | Sixth | 6 out |
| Monday, May 6 |
| » Defeated Tigers (9-10), 8-6 | Tiger Stadium (1-2) | 7-11 | |
| » Starters: Ray Moore vs Don Lee | Seventh | 5½ out |
| Tuesday, May 7 |
| » Lost to Athletics (11-9), 3-2 | Municipal Stadium (0-1) | 7-12 | |
| » Starters: Hal Brown vs Ryne Duren | Seventh | 5½ out |
| Wednesday, May 8 |
| » Defeated Athletics (11-10), 11-2 | Municipal Stadium (1-1) | 8-12 | |
| » Starters: Billy Loes vs Alex Kellner | Sixth | 4½ out |
| Friday, May 10 |
| » Defeated Yankees (12-8), 4-1 | Memorial Stadium (4-2) | 9-12 | Won 2 |
| » Starters: Johnny Kucks vs Connie Johnson | Seventh | 4½ out |
| Saturday, May 11 |
| » Lost to Yankees (13-8), 6-4 | Memorial Stadium (4-3) | 9-13 | |
| » Starters: Don Larsen vs Ray Moore | Sixth | 5 out |
| Sunday, May 12 |
| » Lost to Yankees (14-8), 4-3 | Memorial Stadium (4-4) | 9-14 | Lost 2 |
| » Starters: Bobby Shantz vs Hal Brown | Seventh | 6 out |
| Wednesday, May 15 |
| » Lost to Indians (14-9), 11-8 | Memorial Stadium (4-5) | 9-15 | Lost 3 |
| » Starters: Bob Lemon vs Connie Johnson | Sixth | 7 out |
| Thursday, May 16 |
| » Lost to Indians (15-9), 4-3 | Memorial Stadium (4-6) | 9-16 | Lost 4 |
| » Starters: Early Wynn vs Ray Moore | Seventh | 8 out |
| Friday, May 17 |
| » Lost to White Sox (17-7), 3-2 | Memorial Stadium (4-7) | 9-17 | Lost 5 |
| » Starters: Dick Donovan vs Art Ceccarelli | Sixth | 9 out |
| Saturday, May 18 |
| » Tied White Sox, 4-4 | Memorial Stadium (4-7) | 9-17 | |
| » Starters: Jack Harshman vs Bill Wight | Sixth | 9 out |
| Sunday, May 19 |
| » Defeated Athletics (13-17), 10-2 | Memorial Stadium (5-7) | 10-17 | |
| » Starters: Tom Morgan vs Billy Loes | Sixth | 9 out |
| » Tied Athletics, 0-0 | Memorial Stadium (5-7) | 10-17 | |
| » Starters: Rip Coleman vs Hal Brown | Sixth | 9 out |
| Monday, May 20 |
| » Defeated Athletics (13-18), 2-0 | Memorial Stadium (6-7) | 11-17 | Won 2 |
| » Starters: Ned Garver vs Connie Johnson | Sixth | 8½ out |
| Tuesday, May 21 |
| » Lost to Tigers (17-15), 2-1 | Memorial Stadium (6-8) | 11-18 | |
| » Starters: Jim Bunning vs Ray Moore | Seventh | 9½ out |
| Wednesday, May 22 |
| » Defeated Tigers (17-16), 4-3 | Memorial Stadium (7-8) | 12-18 | |
| » Starters: Billy Hoeft vs Art Ceccarelli | Seventh | 9½ out |
| Friday, May 24 |
| » Lost to Red Sox (17-16), 4-3 | Memorial Stadium (7-9) | 12-19 | |
| » Starters: Frank Sullivan vs Bill Wight | Sixth | 9½ out |
| Saturday, May 25 |
| » Defeated Red Sox (17-17), 12-0 | Memorial Stadium (8-9) | 13-19 | |
| » Starters: Bob Porterfield vs Billy Loes | Fifth | 9½ out |
| Sunday, May 26 |
| » Lost to Red Sox (18-17), 9-0 | Memorial Stadium (8-10) | 13-20 | |
| » Starters: Dean Stone vs Ray Moore | Sixth | 10½ out |
| » Lost to Red Sox (19-17), 5-4 | Memorial Stadium (8-11) | 13-21 | Lost 2 |
| » Starters: Dave Sisler vs Mike Fornieles | Sixth | 10½ out |
| Monday, May 27 |
| » Lost to Senators (12-28), 10-6 | Griffith Stadium (2-4) | 13-22 | Lost 3 |
| » Starters: Connie Johnson vs Russ Kemmerer | Seventh | 10½ out |
| Wednesday, May 29 |
| » Defeated Red Sox (19-20), 3-1 | Fenway Park (2-1) | 14-22 | |
| » Starters: Billy Loes vs George Susce | Sixth | 10 out |
| Thursday, May 30 |
| » Lost to Red Sox (20-20), 7-6 | Fenway Park (2-2) | 14-23 | |
| » Starters: Art Ceccarelli vs Dean Stone | Seventh | 12 out |
| » Lost to Red Sox (21-20), 16-5 | Fenway Park (2-3) | 14-24 | Lost 2 |
| » Starters: Mike Fornieles vs Dave Sisler | Seventh | 12 out |
| Friday, May 31 |
| » Defeated Yankees (23-16), 3-1 | Yankee Stadium (1-1) | 15-24 | |
| » Starters: Ray Moore vs Bob Turley | Seventh | 12 out |
| Saturday, June 1 |
| » Defeated Yankees (23-17), 4-3 | Yankee Stadium (2-1) | 16-24 | Won 2 |
| » Starters: Connie Johnson vs Johnny Kucks | Sixth | 12 out |
| Sunday, June 2 |
| » Defeated Yankees (23-18), 3-2 | Yankee Stadium (3-1) | 17-24 | Won 3 |
| » Starters: Bill Wight vs Art Ditmar | Seventh | 12 out |
| » Lost to Yankees (24-18), 4-0 | Yankee Stadium (3-2) | 17-25 | |
| » Starters: Hal Brown vs Ralph Terry | Seventh | 12 out |
| Tuesday, June 4 |
| » Defeated Athletics (19-25), 9-7 | Municipal Stadium (2-1) | 18-25 | |
| » Starters: Billy Loes vs Tom Morgan | Seventh | 12 out |
| Wednesday, June 5 |
| » Lost to Athletics (20-25), 3-2 | Municipal Stadium (2-2) | 18-26 | |
| » Starters: Ray Moore vs Arnie Portocarrero | Sixth | 13 out |
| Thursday, June 6 |
| » Defeated Athletics (20-26), 8-3 | Municipal Stadium (3-2) | 19-26 | |
| » Starters: Connie Johnson vs Ned Garver | Seventh | 13 out |
| Friday, June 7 |
| » Defeated White Sox (31-13), 3-2 | Comiskey Park I (1-2) | 20-26 | Won 2 |
| » Starters: Art Ceccarelli vs Jack Harshman | Seventh | 12 out |
| Saturday, June 8 |
| » Lost to White Sox (32-13), 2-0 | Comiskey Park I (1-3) | 20-27 | |
| » Starters: Bill Wight vs Billy Pierce | Seventh | 13 out |
| Sunday, June 9 |
| » Defeated White Sox (32-14), 7-5 | Comiskey Park I (2-3) | 21-27 | |
| » Starters: Ray Moore vs Bill Fischer | Sixth | 11 out |
| » Defeated White Sox (32-15), 5-0 | Comiskey Park I (3-3) | 22-27 | Won 2 |
| » Starters: Billy O'Dell vs Dick Donovan | Sixth | 11 out |
| Tuesday, June 11 |
| » Defeated Tigers (27-25), 4-1 | Tiger Stadium (2-2) | 23-27 | Won 3 |
| » Starters: Connie Johnson vs Billy Hoeft | Sixth | 10 out |
| Wednesday, June 12 |
| » Lost to Tigers (28-25), 4-2 | Tiger Stadium (2-3) | 23-28 | |
| » Starters: Art Ceccarelli vs Jim Bunning | Sixth | 11 out |
| Thursday, June 13 |
| » Lost to Tigers (29-25), 2-1 | Tiger Stadium (2-4) | 23-29 | Lost 2 |
| » Starters: Ray Moore vs Paul Foytack | Sixth | 11 out |
| » Major-league debuts: John Tsitouris (Tigers) |
| Friday, June 14 |
| » Lost to Indians (28-24), 7-2 | Cleveland Stadium (0-1) | 23-30 | Lost 3 |
| » Starters: Bill Wight vs Mike Garcia | Sixth | 12 out |
| Saturday, June 15 |
| » Defeated Indians (28-25), 8-3 | Cleveland Stadium (1-1) | 24-30 | |
| » Starters: Billy Loes vs Bud Daley | Sixth | 11 out |
| Sunday, June 16 |
| » Lost to Indians (29-25), 4-3 | Cleveland Stadium (1-2) | 24-31 | |
| » Starters: Connie Johnson vs Don Mossi | Sixth | 13 out |
| » Lost to Indians (30-25), 5-1 | Cleveland Stadium (1-3) | 24-32 | Lost 2 |
| » Starters: Billy O'Dell vs Early Wynn | Sixth | 13 out |
| Tuesday, June 18 |
| » Defeated White Sox (36-19), 2-1 | Memorial Stadium (9-11) | 25-32 | |
| » Starters: Billy Pierce vs Ray Moore | Sixth | 12 out |
| Wednesday, June 19 |
| » Lost to White Sox (37-19), 3-1 | Memorial Stadium (9-12) | 25-33 | |
| » Starters: Bob Keegan vs Art Ceccarelli | Sixth | 13 out |
| Thursday, June 20 |
| » Defeated White Sox (37-20), 4-1 | Memorial Stadium (10-12) | 26-33 | |
| » Starters: Bill Fischer vs Billy Loes | Sixth | 12 out |
| Friday, June 21 |
| » Defeated Tigers (32-29), 6-5 | Memorial Stadium (11-12) | 27-33 | Won 2 |
| » Starters: Jim Bunning vs Connie Johnson | Sixth | 11 out |
| Saturday, June 22 |
| » Lost to Tigers (33-29), 2-1 | Memorial Stadium (11-13) | 27-34 | |
| » Starters: Paul Foytack vs Billy O'Dell | Sixth | 11½ out |
| Sunday, June 23 |
| » Defeated Tigers (33-30), 5-4 | Memorial Stadium (12-13) | 28-34 | |
| » Starters: Billy Hoeft vs Ray Moore | Sixth | 11 out |
| Monday, June 24 |
| » Defeated Tigers (33-31), 6-0 | Memorial Stadium (13-13) | 29-34 | Won 2 |
| » Starters: Duke Maas vs Hal Brown | Fifth | 10½ out |
| Future Oriole Doug Jones is born in Lebanon, IN. |
| Tuesday, June 25 |
| » Defeated Athletics (25-39), 5-0 | Memorial Stadium (14-13) | 30-34 | Won 3 |
| » Starters: Jack Urban vs Billy Loes | Sixth | 10 out |
| Wednesday, June 26 |
| » Defeated Athletics (25-40), 1-0 | Memorial Stadium (15-13) | 31-34 | Won 4 |
| » Starters: Arnie Portocarrero vs Connie Johnson | Sixth | 10 out |
| Future Oriole Mike Griffin is born in Colusa, CA. |
| Thursday, June 27 |
| » Major-league debuts: Bobo Osborne (Tigers) |
| Friday, June 28 |
| » Defeated Indians (36-30), 6-0 | Memorial Stadium (16-13) | 32-34 | Won 5 |
| » Starters: Mike Garcia vs Ray Moore | Fifth | 9 out |
| Saturday, June 29 |
| » Lost to Indians (37-30), 2-1 | Memorial Stadium (16-14) | 32-35 | |
| » Starters: Stan Pitula vs Billy O'Dell | Fifth | 9½ out |
| » Defeated Indians (37-31), 5-1 | Memorial Stadium (17-14) | 33-35 | |
| » Starters: Don Mossi vs Bill Wight | Fifth | 9½ out |
| Sunday, June 30 |
| » Defeated Indians (37-32), 12-3 | Memorial Stadium (18-14) | 34-35 | Won 2 |
| » Starters: Bob Lemon vs Billy Loes | Sixth | 10 out |
| Monday, July 1 |
| » Lost to Yankees (45-25), 3-2 | Memorial Stadium (18-15) | 34-36 | |
| » Starters: Johnny Kucks vs Hal Brown | Sixth | 11 out |
| Tuesday, July 2 |
| » Lost to Yankees (46-25), 6-4 | Memorial Stadium (18-16) | 34-37 | Lost 2 |
| » Starters: Tommy Byrne vs Connie Johnson | Sixth | 12 out |
| Wednesday, July 3 |
| » Defeated Senators (25-52), 8-3 | Memorial Stadium (19-16) | 35-37 | |
| » Starters: Jim Heise vs Ray Moore | Sixth | 12 out |
| Thursday, July 4 |
| » Defeated Senators (25-53), 3-2 | Memorial Stadium (20-16) | 36-37 | Won 2 |
| » Starters: Chuck Stobbs vs Bill Wight | Fifth | 11½ out |
| Friday, July 5 |
| » Lost to Red Sox (41-36), 7-5 | Fenway Park (2-4) | 36-38 | |
| » Starters: Billy Loes vs Mike Fornieles | Sixth | 12½ out |
| Saturday, July 6 |
| » Lost to Red Sox (42-36), 11-2 | Fenway Park (2-5) | 36-39 | Lost 2 |
| » Starters: Hal Brown vs Frank Sullivan | Sixth | 13½ out |
| » Major-league debuts: Jerry Walker (Orioles) |
| Sunday, July 7 |
| » Defeated Red Sox (42-37), 8-4 | Fenway Park (3-5) | 37-39 | |
| » Starters: Connie Johnson vs Tom Brewer | Sixth | 13½ out |
| Thursday, July 11 |
| » Defeated Indians (39-39), 5-4 | Cleveland Stadium (2-3) | 38-39 | Won 2 |
| » Starters: Ray Moore vs Ray Narleski | Fourth | 13 out |
| » Defeated Indians (39-40), 5-4 | Cleveland Stadium (3-3) | 39-39 | Won 3 |
| » Starters: Bill Wight vs Bob Lemon | Fourth | 13 out |
| Friday, July 12 |
| » Lost to Indians (40-40), 8-6 | Cleveland Stadium (3-4) | 39-40 | |
| » Starters: Connie Johnson vs Early Wynn | Fifth | 14 out |
| Saturday, July 13 |
| » Lost to Indians (41-40), 5-2 | Cleveland Stadium (3-5) | 39-41 | Lost 2 |
| » Starters: Billy O'Dell vs Don Mossi | Sixth | 14 out |
| Sunday, July 14 |
| » Lost to Tigers (41-41), 10-2 | Tiger Stadium (2-5) | 39-42 | Lost 3 |
| » Starters: Hal Brown vs Billy Hoeft | Sixth | 15 out |
| » Lost to Tigers (42-41), 7-6 | Tiger Stadium (2-6) | 39-43 | Lost 4 |
| » Starters: Billy Loes vs Don Lee | Sixth | 15 out |
| Tuesday, July 16 |
| » Defeated White Sox (51-32), 3-1 | Comiskey Park I (4-3) | 40-43 | |
| » Starters: Ray Moore vs Jim Wilson | Sixth | 15 out |
| Wednesday, July 17 |
| » Lost to White Sox (52-32), 3-1 | Comiskey Park I (4-4) | 40-44 | |
| » Starters: Bill Wight vs Bob Keegan | Sixth | 16 out |
| Thursday, July 18 |
| » Defeated White Sox (52-33), 6-2 | Comiskey Park I (5-4) | 41-44 | |
| » Starters: Billy O'Dell vs Jack Harshman | Sixth | 16 out |
| Friday, July 19 |
| » Defeated Athletics (32-54), 4-2 | Municipal Stadium (4-2) | 42-44 | Won 2 |
| » Starters: Billy Loes vs Ned Garver | Sixth | 16 out |
| Saturday, July 20 |
| » Lost to Athletics (33-54), 6-5 | Municipal Stadium (4-3) | 42-45 | |
| » Starters: Connie Johnson vs Arnie Portocarrero | Sixth | 16 out |
| Sunday, July 21 |
| » Defeated Athletics (33-55), 7-2 | Municipal Stadium (5-3) | 43-45 | |
| » Starters: Hal Brown vs Wally Burnette | Sixth | 16 out |
| » Lost to Athletics (34-55), 3-2 | Municipal Stadium (5-4) | 43-46 | |
| » Starters: Ray Moore vs Alex Kellner | Sixth | 16 out |
| Tuesday, July 23 |
| » Lost to Tigers (45-45), 5-2 | Memorial Stadium (20-17) | 43-47 | Lost 2 |
| » Starters: Billy Hoeft vs Billy O'Dell | Sixth | 17 out |
| Wednesday, July 24 |
| » Lost to Tigers (46-45), 5-1 | Memorial Stadium (20-18) | 43-48 | Lost 3 |
| » Starters: Paul Foytack vs Billy Loes | Sixth | 17 out |
| Thursday, July 25 |
| » Defeated Tigers (46-46), 3-0 | Memorial Stadium (21-18) | 44-48 | |
| » Starters: Frank Lary vs Connie Johnson | Sixth | 16 out |
| Friday, July 26 |
| » Defeated White Sox (56-36), 5-2 | Memorial Stadium (22-18) | 45-48 | Won 2 |
| » Starters: Jack Harshman vs Ray Moore | Sixth | 15½ out |
| » Lost to White Sox (57-36), 1-0 | Memorial Stadium (22-19) | 45-49 | |
| » Starters: Jim Wilson vs Ken Lehman | Sixth | 15½ out |
| Saturday, July 27 |
| » Defeated White Sox (57-37), 5-2 | Memorial Stadium (23-19) | 46-49 | |
| » Starters: Bob Keegan vs Bill Wight | Sixth | 15½ out |
| Future Oriole Floyd Rayford is born in Memphis, TN. |
| Sunday, July 28 |
| » Lost to White Sox (58-37), 4-3 | Memorial Stadium (23-20) | 46-50 | |
| » Starters: Jack Harshman vs Billy O'Dell | Fifth | 16 out |
| Monday, July 29 |
| » Lost to White Sox (59-37), 5-0 | Memorial Stadium (23-21) | 46-51 | Lost 2 |
| » Starters: Billy Pierce vs Hal Brown | Sixth | 16½ out |
| Tuesday, July 30 |
| » Lost to Indians (49-49), 6-0 | Memorial Stadium (23-22) | 46-52 | Lost 3 |
| » Starters: Johnny Gray vs Billy Loes | Sixth | 17½ out |
| Wednesday, July 31 |
| » Lost to Indians (50-49), 4-0 | Memorial Stadium (23-23) | 46-53 | Lost 4 |
| » Starters: Ray Narleski vs Ray Moore | Sixth | 19 out |
| Friday, August 2 |
| » Defeated Athletics (36-64), 5-4 | Memorial Stadium (24-23) | 47-53 | |
| » Starters: Alex Kellner vs Jerry Walker | Fifth | 18½ out |
| » Defeated Athletics (36-65), 10-2 | Memorial Stadium (25-23) | 48-53 | Won 2 |
| » Starters: Ned Garver vs Connie Johnson | Fifth | 18½ out |
| Saturday, August 3 |
| » Defeated Athletics (36-66), 7-6 | Memorial Stadium (26-23) | 49-53 | Won 3 |
| » Starters: Ralph Terry vs Hal Brown | Fifth | 18½ out |
| Sunday, August 4 |
| » Defeated Athletics (36-67), 5-0 | Memorial Stadium (27-23) | 50-53 | Won 4 |
| » Starters: Arnie Portocarrero vs Billy Loes | Fifth | 19 out |
| Tuesday, August 6 |
| » Defeated Red Sox (56-48), 2-1 | Memorial Stadium (28-23) | 51-53 | Won 5 |
| » Starters: Willard Nixon vs Ray Moore | Fifth | 18½ out |
| Wednesday, August 7 |
| » Lost to Red Sox (57-48), 5-2 | Memorial Stadium (28-24) | 51-54 | |
| » Starters: Frank Sullivan vs Connie Johnson | Sixth | 18½ out |
| Thursday, August 8 |
| » Defeated Red Sox (57-49), 3-1 | Memorial Stadium (29-24) | 52-54 | |
| » Starters: Mike Fornieles vs Billy O'Dell | Fifth | 17½ out |
| Friday, August 9 |
| » Defeated Yankees (70-38), 4-3 | Memorial Stadium (30-24) | 53-54 | Won 2 |
| » Starters: Whitey Ford vs Bill Wight | Fourth | 16½ out |
| Saturday, August 10 |
| » Lost to Yankees (71-38), 6-3 | Memorial Stadium (30-25) | 53-55 | |
| » Starters: Bob Turley vs Ray Moore | Fourth | 17½ out |
| » Major-league debuts: Milt Pappas (Orioles) |
| Sunday, August 11 |
| » Lost to Yankees (72-38), 7-2 | Memorial Stadium (30-26) | 53-56 | Lost 2 |
| » Starters: Johnny Kucks vs Ken Lehman | Fourth | 18½ out |
| Tuesday, August 13 |
| » Defeated Senators (42-71), 5-3 | Griffith Stadium (3-4) | 54-56 | |
| » Starters: Connie Johnson vs Russ Kemmerer | Fourth | 18½ out |
| Wednesday, August 14 |
| » Defeated Senators (42-72), 4-2 | Griffith Stadium (4-4) | 55-56 | Won 2 |
| » Starters: Hal Brown vs Pedro Ramos | Fourth | 17½ out |
| Friday, August 16 |
| » Defeated Yankees (74-40), 4-3 | Yankee Stadium (4-2) | 56-56 | Won 3 |
| » Starters: Bill Wight vs Johnny Kucks | Fourth | 17 out |
| Saturday, August 17 |
| » Lost to Yankees (75-40), 6-2 | Yankee Stadium (4-3) | 56-57 | |
| » Starters: Ray Moore vs Bobby Shantz | Fourth | 18 out |
| Sunday, August 18 |
| » Lost to Yankees (76-40), 7-0 | Yankee Stadium (4-4) | 56-58 | Lost 2 |
| » Starters: Art Ceccarelli vs Tom Sturdivant | Fifth | 20 out |
| » Lost to Yankees (77-40), 3-2 | Yankee Stadium (4-5) | 56-59 | Lost 3 |
| » Starters: Connie Johnson vs Don Larsen | Fifth | 20 out |
| Tuesday, August 20 |
| » Lost to Tigers (59-59), 5-1 | Tiger Stadium (2-7) | 56-60 | Lost 4 |
| » Starters: Hal Brown vs Jim Bunning | Fifth | 20 out |
| Wednesday, August 21 |
| » Defeated Tigers (59-60), 9-3 | Tiger Stadium (3-7) | 57-60 | |
| » Starters: Ray Moore vs Billy Hoeft | Fifth | 19 out |
| Thursday, August 22 |
| » Lost to Tigers (60-60), 4-0 | Tiger Stadium (3-8) | 57-61 | |
| » Starters: Billy O'Dell vs Frank Lary | Fifth | 20 out |
| Friday, August 23 |
| » Defeated Athletics (47-75), 2-1 | Municipal Stadium (6-4) | 58-61 | |
| » Starters: Connie Johnson vs Alex Kellner | Fifth | 19 out |
| Future Oriole Mike Boddicker is born in Cedar Rapids, IA. |
| Saturday, August 24 |
| » Defeated Athletics (47-76), 4-2 | Municipal Stadium (7-4) | 59-61 | Won 2 |
| » Starters: Ken Lehman vs Ned Garver | Fifth | 19 out |
| Sunday, August 25 |
| » Lost to White Sox (74-48), 6-2 | Comiskey Park I (5-5) | 59-62 | |
| » Starters: Art Ceccarelli vs Bob Keegan | Fifth | 19½ out |
| » Lost to White Sox (75-48), 3-0 | Comiskey Park I (5-6) | 59-63 | Lost 2 |
| » Starters: Bill Wight vs Jack Harshman | Fifth | 19½ out |
| » Major-league debuts: Lenny Green (Orioles) |
| Tuesday, August 27 |
| » Lost to Indians (61-65), 5-4 | Cleveland Stadium (3-6) | 59-64 | Lost 3 |
| » Starters: Ray Moore vs Early Wynn | Sixth | 20 out |
| Wednesday, August 28 |
| » Defeated Indians (61-66), 19-6 | Cleveland Stadium (4-6) | 60-64 | |
| » Starters: Connie Johnson vs Ray Narleski | Fifth | 20 out |
| Thursday, August 29 |
| » Lost to Indians (62-66), 13-4 | Cleveland Stadium (4-7) | 60-65 | |
| » Starters: Billy O'Dell vs Mike Garcia | Sixth | 21 out |
| Friday, August 30 |
| » Lost to Red Sox (68-59), 8-1 | Memorial Stadium (30-27) | 60-66 | Lost 2 |
| » Starters: Bob Porterfield vs Billy Loes | Sixth | 21 out |
| Saturday, August 31 |
| » Defeated Red Sox (68-60), 4-1 | Memorial Stadium (31-27) | 61-66 | |
| » Starters: Willard Nixon vs Hal Brown | Sixth | 20 out |
| Sunday, September 1 |
| » Defeated Red Sox (68-61), 2-1 | Memorial Stadium (32-27) | 62-66 | Won 2 |
| » Starters: Mike Fornieles vs Ray Moore | Fifth | 20 out |
| Monday, September 2 |
| » Defeated Yankees (83-48), 8-7 | Memorial Stadium (33-27) | 63-66 | Won 3 |
| » Starters: Don Larsen vs Bill Wight | Fifth | 18 out |
| » Defeated Yankees (83-49), 6-1 | Memorial Stadium (34-27) | 64-66 | Won 4 |
| » Starters: Johnny Kucks vs Connie Johnson | Fifth | 18 out |
| Tuesday, September 3 |
| » Lost to Yankees (84-49), 2-0 | Memorial Stadium (34-28) | 64-67 | |
| » Starters: Tom Sturdivant vs Billy O'Dell | Fifth | 19 out |
| Wednesday, September 4 |
| » Defeated Senators (50-82), 1-0 | Memorial Stadium (35-28) | 65-67 | |
| » Starters: Camilo Pascual vs Jerry Walker | Fifth | 18 out |
| Thursday, September 5 |
| » Lost to Senators (51-82), 3-0 | Memorial Stadium (35-29) | 65-68 | |
| » Starters: Chuck Stobbs vs Ray Moore | Fifth | 19 out |
| Friday, September 6 |
| » Lost to Red Sox (72-62), 4-3 | Fenway Park (3-6) | 65-69 | Lost 2 |
| » Starters: Hal Brown vs Bob Porterfield | Fifth | 19 out |
| Saturday, September 7 |
| » Lost to Red Sox (73-62), 4-3 | Fenway Park (3-7) | 65-70 | Lost 3 |
| » Starters: Connie Johnson vs Frank Sullivan | Sixth | 20 out |
| Sunday, September 8 |
| » Lost to Red Sox (74-62), 2-0 | Fenway Park (3-8) | 65-71 | Lost 4 |
| » Starters: Billy O'Dell vs Mike Fornieles | Sixth | 21 out |
| Wednesday, September 11 |
| » Lost to Athletics (52-84), 7-3 | Memorial Stadium (35-30) | 65-72 | Lost 5 |
| » Starters: Ralph Terry vs Ray Moore | Sixth | 21 out |
| » Defeated Athletics (52-85), 6-2 | Memorial Stadium (36-30) | 66-72 | |
| » Starters: Tom Gorman vs Jerry Walker | Sixth | 21 out |
| Saturday, September 14 |
| » Defeated Tigers (72-68), 3-1 | Memorial Stadium (37-30) | 67-72 | Won 2 |
| » Starters: Billy Hoeft vs Billy O'Dell | Sixth | 21 out |
| » Lost to Tigers (73-68), 4-3 | Memorial Stadium (37-31) | 67-73 | |
| » Starters: Paul Foytack vs Connie Johnson | Sixth | 21 out |
| Sunday, September 15 |
| » Defeated Indians (68-73), 5-4 | Memorial Stadium (38-31) | 68-73 | |
| » Starters: Early Wynn vs Bill Wight | Fifth | 21 out |
| » Defeated Indians (68-74), 4-3 | Memorial Stadium (39-31) | 69-73 | Won 2 |
| » Starters: Don Mossi vs Ray Moore | Fifth | 21 out |
| Tuesday, September 17 |
| » Defeated White Sox (84-58), 7-5 | Memorial Stadium (40-31) | 70-73 | Won 3 |
| » Starters: Billy Pierce vs Hal Brown | Fifth | 21 out |
| Wednesday, September 18 |
| » Lost to White Sox (85-58), 7-5 | Memorial Stadium (40-32) | 70-74 | |
| » Starters: Jim Wilson vs Don Ferrarese | Fifth | 22 out |
| Friday, September 20 |
| » Defeated Senators (54-92), 1-0 | Memorial Stadium (41-32) | 71-74 | |
| » Starters: Tex Clevenger vs Connie Johnson | Fifth | 22 out |
| Saturday, September 21 |
| » Lost to Senators (55-92), 8-1 | Memorial Stadium (41-33) | 71-75 | |
| » Starters: Bob Wiesler vs Ray Moore | Fifth | 22 out |
| Sunday, September 22 |
| » Defeated Senators (55-93), 6-5 | Memorial Stadium (42-33) | 72-75 | |
| » Starters: Camilo Pascual vs Art Houtteman | Fifth | 22 out |
| Wednesday, September 25 |
| » Lost to Yankees (96-54), 5-1 | Yankee Stadium (4-6) | 72-76 | |
| » Starters: Connie Johnson vs Don Larsen | Fifth | 22 out |
| » Defeated Yankees (96-55), 4-2 | Yankee Stadium (5-6) | 73-76 | |
| » Starters: Billy O'Dell vs Whitey Ford | Fifth | 22 out |
| Thursday, September 26 |
| Future Oriole Doug Sisk is born in Renton, WA. |
| Friday, September 27 |
| » Defeated Senators (55-97), 7-3 | Griffith Stadium (5-4) | 74-76 | Won 2 |
| » Starters: Hal Brown vs Bob Wiesler | Fifth | 22 out |
| Saturday, September 28 |
| » Defeated Senators (55-98), 9-1 | Griffith Stadium (6-4) | 75-76 | Won 3 |
| » Starters: Bill Wight vs Don Minnick | Fifth | 22 out |
| Sunday, September 29 |
| » Defeated Senators (55-99), 7-3 | Griffith Stadium (7-4) | 76-76 | Won 4 |
| » Starters: Connie Johnson vs Hal Griggs | Fifth | 21 out |
| Future Oriole Craig Lefferts is born in Munich, W.Germany. |
| Wednesday, December 4 |
| Future Oriole Lee Smith is born in Shreveport, LA. |
Game information provided by Retrosheet (www.retrosheet.org) |
