| Thursday, February 7 |
| Future Athletic Carney Lansford is born in San Jose, CA. |
| Monday, April 15 |
| » Major-league debuts: Neil Chrisley (Senators) |
| Tuesday, April 16 |
| » Defeated Tigers (0-1), 2-1 | Municipal Stadium (1-0) | 1-0 | |
| » Starters: Frank Lary vs Tom Morgan | First | -- |
| » Major-league debuts: Milt Graff (Athletics) |
| Wednesday, April 17 |
| » Defeated Tigers (0-2), 5-4 | Municipal Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Jim Bunning vs Ned Garver | First | -- |
| Thursday, April 18 |
| » Lost to White Sox (2-0), 6-2 | Comiskey Park I (0-1) | 2-1 | |
| » Starters: Alex Kellner vs Jack Harshman | Second | ½ out |
| Saturday, April 20 |
| » Lost to White Sox (3-0), 11-7 | Comiskey Park I (0-2) | 2-2 | Lost 2 |
| » Starters: Gene Host vs Dick Donovan | Second | 1½ out |
| Sunday, April 21 |
| » Lost to White Sox (4-0), 1-0 | Comiskey Park I (0-3) | 2-3 | Lost 3 |
| » Starters: Tom Morgan vs Jim Wilson | Fifth | 2½ out |
| Monday, April 22 |
| » Defeated Tigers (2-4), 11-7 | Tiger Stadium (1-0) | 3-3 | |
| » Starters: Mickey McDermott vs Paul Foytack | Third | 2 out |
| Tuesday, April 23 |
| » Defeated Tigers (2-5), 5-4 | Tiger Stadium (2-0) | 4-3 | Won 2 |
| » Starters: Rip Coleman vs Don Lee | Third | 1 out |
| » Major-league debuts: Don Lee (Tigers) |
| Wednesday, April 24 |
| » Defeated Indians (2-4), 17-6 | Municipal Stadium (3-0) | 5-3 | Won 3 |
| » Starters: Bob Lemon vs Ned Garver | Third | 1½ out |
| Thursday, April 25 |
| » Lost to Indians (3-4), 5-3 | Municipal Stadium (3-1) | 5-4 | |
| » Starters: Early Wynn vs Wally Burnette | Fourth | 1½ out |
| Friday, April 26 |
| » Lost to White Sox (6-1), 4-3 | Municipal Stadium (3-2) | 5-5 | Lost 2 |
| » Starters: Billy Pierce vs Tom Morgan | Fourth | 2½ out |
| Saturday, April 27 |
| » Defeated White Sox (6-2), 3-2 | Municipal Stadium (4-2) | 6-5 | |
| » Starters: Dick Donovan vs Alex Kellner | Fourth | 1½ out |
| Sunday, April 28 |
| » Lost to White Sox (7-2), 5-3 | Municipal Stadium (4-3) | 6-6 | |
| » Starters: Jim Wilson vs Rip Coleman | Fourth | 2½ out |
| Tuesday, April 30 |
| » Lost to Red Sox (8-4), 3-1 | Municipal Stadium (4-4) | 6-7 | Lost 2 |
| » Starters: Willard Nixon vs Ned Garver | Fifth | 3½ out |
| Wednesday, May 1 |
| » Defeated Red Sox (8-5), 7-5 | Municipal Stadium (5-4) | 7-7 | |
| » Starters: Dave Sisler vs Tom Morgan | Fifth | 3½ out |
| Thursday, May 2 |
| » Lost to Yankees (8-5), 3-1 | Municipal Stadium (5-5) | 7-8 | |
| » Starters: Tom Sturdivant vs Ryne Duren | Fifth | 4½ out |
| Friday, May 3 |
| » Lost to Yankees (9-5), 8-5 | Municipal Stadium (5-6) | 7-9 | Lost 2 |
| » Starters: Bob Turley vs Wally Burnette | Fifth | 5½ out |
| Saturday, May 4 |
| » Defeated Senators (5-14), 8-2 | Municipal Stadium (6-6) | 8-9 | |
| » Starters: Ted Abernathy vs Arnie Portocarrero | Fifth | 4½ out |
| Sunday, May 5 |
| » Defeated Senators (5-15), 7-2 | Municipal Stadium (7-6) | 9-9 | Won 2 |
| » Starters: Camilo Pascual vs Tom Morgan | Fifth | 3½ out |
| Monday, May 6 |
| » Defeated Senators (5-16), 8-2 | Municipal Stadium (8-6) | 10-9 | Won 3 |
| » Starters: Chuck Stobbs vs Ned Garver | Fourth | 3 out |
| Tuesday, May 7 |
| » Defeated Orioles (7-12), 3-2 | Municipal Stadium (9-6) | 11-9 | Won 4 |
| » Starters: Hal Brown vs Ryne Duren | Fourth | 2 out |
| Wednesday, May 8 |
| » Lost to Orioles (8-12), 11-2 | Municipal Stadium (9-7) | 11-10 | |
| » Starters: Billy Loes vs Alex Kellner | Fifth | 2 out |
| Friday, May 10 |
| » Lost to Indians (11-8), 4-1 | Cleveland Stadium (0-1) | 11-11 | Lost 2 |
| » Starters: Gene Host vs Mike Garcia | Fifth | 3 out |
| Saturday, May 11 |
| » Lost to Indians (12-8), 2-1 | Cleveland Stadium (0-2) | 11-12 | Lost 3 |
| » Starters: Tom Morgan vs Bob Lemon | Fifth | 3½ out |
| Sunday, May 12 |
| » Defeated Indians (12-9), 9-2 | Cleveland Stadium (1-2) | 12-12 | |
| » Starters: Mickey McDermott vs Early Wynn | Fifth | 4 out |
| » Lost to Indians (13-9), 7-4 | Cleveland Stadium (1-3) | 12-13 | |
| » Starters: Ryne Duren vs Bud Daley | Fifth | 4 out |
| Wednesday, May 15 |
| » Lost to Yankees (15-8), 3-0 | Yankee Stadium (0-1) | 12-14 | Lost 2 |
| » Starters: Ned Garver vs Tom Sturdivant | Fifth | 5 out |
| Thursday, May 16 |
| » Lost to Yankees (16-8), 3-0 | Yankee Stadium (0-2) | 12-15 | Lost 3 |
| » Starters: Alex Kellner vs Bob Turley | Sixth | 6 out |
| Friday, May 17 |
| » Lost to Red Sox (15-13), 4-3 | Fenway Park (0-1) | 12-16 | Lost 4 |
| » Starters: Ryne Duren vs Tom Brewer | Fifth | 7 out |
| Saturday, May 18 |
| » Defeated Red Sox (15-14), 7-5 | Fenway Park (1-1) | 13-16 | |
| » Starters: Wally Burnette vs Willard Nixon | Fifth | 6½ out |
| Sunday, May 19 |
| » Lost to Orioles (10-17), 10-2 | Memorial Stadium (0-1) | 13-17 | |
| » Starters: Tom Morgan vs Billy Loes | Fifth | 7½ out |
| » Tied Orioles, 0-0 | Memorial Stadium (0-1) | 13-17 | |
| » Starters: Rip Coleman vs Hal Brown | Fifth | 7½ out |
| Future Athletic Ben Callahan is born in Mount Airy, NC. |
| Monday, May 20 |
| » Lost to Orioles (11-17), 2-0 | Memorial Stadium (0-2) | 13-18 | Lost 2 |
| » Starters: Ned Garver vs Connie Johnson | Fifth | 8 out |
| Tuesday, May 21 |
| » Lost to Senators (10-24), 3-0 | Griffith Stadium (0-1) | 13-19 | Lost 3 |
| » Starters: Ryne Duren vs Camilo Pascual | Sixth | 9 out |
| Wednesday, May 22 |
| » Defeated Senators (10-25), 8-6 | Griffith Stadium (1-1) | 14-19 | |
| » Starters: Alex Kellner vs Ted Abernathy | Sixth | 9 out |
| Saturday, May 25 |
| » Defeated Tigers (17-17), 5-3 | Municipal Stadium (10-7) | 15-19 | Won 2 |
| » Starters: Paul Foytack vs Tom Morgan | Fourth | 8½ out |
| Sunday, May 26 |
| » Defeated Tigers (17-18), 3-1 | Municipal Stadium (11-7) | 16-19 | Won 3 |
| » Starters: Duke Maas vs Ned Garver | Fifth | 8 out |
| Monday, May 27 |
| » Defeated White Sox (22-10), 7-1 | Comiskey Park I (1-3) | 17-19 | Won 4 |
| » Starters: Alex Kellner vs Jim Wilson | Sixth | 7 out |
| Tuesday, May 28 |
| » Lost to White Sox (23-10), 3-1 | Comiskey Park I (1-4) | 17-20 | |
| » Starters: Rip Coleman vs Bill Fischer | Sixth | 8 out |
| Wednesday, May 29 |
| » Lost to Tigers (19-19), 4-3 | Tiger Stadium (2-1) | 17-21 | Lost 2 |
| » Starters: Ryne Duren vs Jim Bunning | Fifth | 8 out |
| Thursday, May 30 |
| » Lost to Tigers (20-19), 6-5 | Tiger Stadium (2-2) | 17-22 | Lost 3 |
| » Starters: Tom Morgan vs Duke Maas | Sixth | 10 out |
| » Lost to Tigers (21-19), 3-2 | Tiger Stadium (2-3) | 17-23 | Lost 4 |
| » Starters: Arnie Portocarrero vs Paul Foytack | Sixth | 10 out |
| Friday, May 31 |
| » Defeated Indians (22-17), 3-1 | Municipal Stadium (12-7) | 18-23 | |
| » Starters: Cal McLish vs Ned Garver | Sixth | 10 out |
| Saturday, June 1 |
| » Lost to Indians (23-17), 3-0 | Municipal Stadium (12-8) | 18-24 | |
| » Starters: Early Wynn vs Wally Burnette | Fifth | 11 out |
| Sunday, June 2 |
| » Defeated Indians (23-18), 8-2 | Municipal Stadium (13-8) | 19-24 | |
| » Starters: Mike Garcia vs Alex Kellner | Sixth | 10½ out |
| Tuesday, June 4 |
| » Lost to Orioles (18-25), 9-7 | Municipal Stadium (13-9) | 19-25 | |
| » Starters: Billy Loes vs Tom Morgan | Sixth | 11½ out |
| Wednesday, June 5 |
| » Defeated Orioles (18-26), 3-2 | Municipal Stadium (14-9) | 20-25 | |
| » Starters: Ray Moore vs Arnie Portocarrero | Fifth | 11½ out |
| Thursday, June 6 |
| » Lost to Orioles (19-26), 8-3 | Municipal Stadium (14-10) | 20-26 | |
| » Starters: Connie Johnson vs Ned Garver | Sixth | 12½ out |
| Friday, June 7 |
| » Defeated Red Sox (23-25), 6-3 | Municipal Stadium (15-10) | 21-26 | |
| » Starters: Willard Nixon vs Wally Burnette | Sixth | 11½ out |
| Sunday, June 9 |
| » Lost to Red Sox (24-25), 8-4 | Municipal Stadium (15-11) | 21-27 | |
| » Starters: Frank Sullivan vs Tom Morgan | Seventh | 12 out |
| » Lost to Red Sox (25-25), 9-5 | Municipal Stadium (15-12) | 21-28 | Lost 2 |
| » Starters: George Susce vs Mickey McDermott | Seventh | 12 out |
| Monday, June 10 |
| » Lost to Red Sox (26-25), 11-4 | Municipal Stadium (15-13) | 21-29 | Lost 3 |
| » Starters: Willard Nixon vs Alex Kellner | Seventh | 12½ out |
| Wednesday, June 12 |
| » Defeated Senators (18-36), 5-3 | Municipal Stadium (16-13) | 22-29 | |
| » Starters: Camilo Pascual vs Arnie Portocarrero | Seventh | 12½ out |
| » Lost to Senators (19-36), 3-2 | Municipal Stadium (16-14) | 22-30 | |
| » Starters: Ted Abernathy vs Ned Garver | Seventh | 12½ out |
| Thursday, June 13 |
| » Defeated Senators (19-37), 6-2 | Municipal Stadium (17-14) | 23-30 | |
| » Starters: Pedro Ramos vs Jack Urban | Seventh | 11½ out |
| Friday, June 14 |
| » Lost to Yankees (31-22), 10-1 | Municipal Stadium (17-15) | 23-31 | |
| » Starters: Tom Sturdivant vs Wally Burnette | Seventh | 12½ out |
| Saturday, June 15 |
| » Lost to Yankees (32-22), 9-2 | Municipal Stadium (17-16) | 23-32 | Lost 2 |
| » Starters: Bob Turley vs Virgil Trucks | Seventh | 12½ out |
| Sunday, June 16 |
| » Lost to Yankees (33-22), 8-6 | Municipal Stadium (17-17) | 23-33 | Lost 3 |
| » Starters: Johnny Kucks vs Tom Morgan | Seventh | 14 out |
| Tuesday, June 18 |
| » Defeated Senators (20-41), 2-0 | Griffith Stadium (2-1) | 24-33 | |
| » Starters: Ralph Terry vs Ted Abernathy | Seventh | 13 out |
| » Major-league debuts: Bob Martyn (Athletics) |
| Wednesday, June 19 |
| » Defeated Senators (20-42), 6-3 | Griffith Stadium (3-1) | 25-33 | Won 2 |
| » Starters: Ned Garver vs Russ Kemmerer | Sixth | 13 out |
| Thursday, June 20 |
| » Lost to Senators (21-42), 9-4 | Griffith Stadium (3-2) | 25-34 | |
| » Starters: Jack Urban vs Pedro Ramos | Seventh | 13 out |
| Friday, June 21 |
| » Lost to Red Sox (30-31), 4-3 | Fenway Park (1-2) | 25-35 | Lost 2 |
| » Starters: Tom Morgan vs Willard Nixon | Seventh | 13 out |
| Saturday, June 22 |
| » Lost to Red Sox (31-31), 5-1 | Fenway Park (1-3) | 25-36 | Lost 3 |
| » Starters: Arnie Portocarrero vs Mike Fornieles | Seventh | 13½ out |
| Sunday, June 23 |
| » Lost to Red Sox (32-31), 10-6 | Fenway Park (1-4) | 25-37 | Lost 4 |
| » Starters: Ned Garver vs Tom Brewer | Seventh | 14½ out |
| » Lost to Red Sox (33-31), 10-1 | Fenway Park (1-5) | 25-38 | Lost 5 |
| » Starters: Ralph Terry vs Frank Sullivan | Seventh | 14½ out |
| Monday, June 24 |
| Future Athletic Doug Jones is born in Lebanon, IN. |
| Tuesday, June 25 |
| » Lost to Orioles (30-34), 5-0 | Memorial Stadium (0-3) | 25-39 | Lost 6 |
| » Starters: Jack Urban vs Billy Loes | Seventh | 15 out |
| Wednesday, June 26 |
| » Lost to Orioles (31-34), 1-0 | Memorial Stadium (0-4) | 25-40 | Lost 7 |
| » Starters: Arnie Portocarrero vs Connie Johnson | Seventh | 16 out |
| Friday, June 28 |
| » Lost to Yankees (41-25), 5-4 | Yankee Stadium (0-3) | 25-41 | Lost 8 |
| » Starters: Virgil Trucks vs Bob Turley | Sixth | 16 out |
| Saturday, June 29 |
| » Lost to Yankees (42-25), 7-6 | Yankee Stadium (0-4) | 25-42 | Lost 9 |
| » Starters: Alex Kellner vs Bobby Shantz | Sixth | 17 out |
| Sunday, June 30 |
| » Lost to Yankees (43-25), 2-1 | Yankee Stadium (0-5) | 25-43 | Lost 10 |
| » Starters: Ralph Terry vs Tom Sturdivant | Seventh | 19 out |
| » Lost to Yankees (44-25), 5-1 | Yankee Stadium (0-6) | 25-44 | Lost 11 |
| » Starters: Jack Urban vs Don Larsen | Seventh | 19 out |
| Monday, July 1 |
| » Defeated Indians (37-33), 10-3 | Cleveland Stadium (2-3) | 26-44 | |
| » Starters: Arnie Portocarrero vs Early Wynn | Seventh | 19 out |
| Wednesday, July 3 |
| » Defeated White Sox (44-28), 5-0 | Municipal Stadium (18-17) | 27-44 | Won 2 |
| » Starters: Dick Donovan vs Virgil Trucks | Seventh | 19½ out |
| Thursday, July 4 |
| » Defeated White Sox (44-29), 5-4 | Municipal Stadium (19-17) | 28-44 | Won 3 |
| » Starters: Jack Harshman vs Alex Kellner | Seventh | 19½ out |
| » Lost to White Sox (45-29), 8-3 | Municipal Stadium (19-18) | 28-45 | |
| » Starters: Bob Keegan vs Ned Garver | Seventh | 19½ out |
| Friday, July 5 |
| » Lost to Tigers (38-38), 8-4 | Tiger Stadium (2-4) | 28-46 | Lost 2 |
| » Starters: Tom Gorman vs Jim Bunning | Seventh | 20½ out |
| Saturday, July 6 |
| » Defeated Tigers (38-39), 3-1 | Tiger Stadium (3-4) | 29-46 | |
| » Starters: Ralph Terry vs Frank Lary | Seventh | 20½ out |
| Sunday, July 7 |
| » Lost to Tigers (39-39), 5-2 | Tiger Stadium (3-5) | 29-47 | |
| » Starters: Arnie Portocarrero vs Paul Foytack | Seventh | 21½ out |
| Thursday, July 11 |
| » Lost to Yankees (52-26), 3-2 | Municipal Stadium (19-19) | 29-48 | Lost 2 |
| » Starters: Bob Turley vs Virgil Trucks | Sixth | 22½ out |
| Friday, July 12 |
| » Lost to Yankees (53-26), 4-2 | Municipal Stadium (19-20) | 29-49 | Lost 3 |
| » Starters: Don Larsen vs Ralph Terry | Sixth | 23½ out |
| Saturday, July 13 |
| » Defeated Yankees (53-27), 6-4 | Municipal Stadium (20-20) | 30-49 | |
| » Starters: Tom Sturdivant vs Arnie Portocarrero | Seventh | 22½ out |
| Sunday, July 14 |
| » Lost to Senators (27-57), 4-1 | Municipal Stadium (20-21) | 30-50 | |
| » Starters: Camilo Pascual vs Ned Garver | Seventh | 22½ out |
| » Defeated Senators (27-58), 11-3 | Municipal Stadium (21-21) | 31-50 | |
| » Starters: Pedro Ramos vs Tom Gorman | Seventh | 22½ out |
| Monday, July 15 |
| » Lost to Senators (28-58), 10-3 | Municipal Stadium (21-22) | 31-51 | |
| » Starters: Russ Kemmerer vs Wally Burnette | Seventh | 23 out |
| Tuesday, July 16 |
| » Lost to Red Sox (45-40), 4-3 | Municipal Stadium (21-23) | 31-52 | Lost 2 |
| » Starters: Mike Fornieles vs Virgil Trucks | Seventh | 24 out |
| Wednesday, July 17 |
| » Defeated Red Sox (45-41), 4-3 | Municipal Stadium (22-23) | 32-52 | |
| » Starters: Frank Sullivan vs Ralph Terry | Seventh | 24 out |
| Thursday, July 18 |
| » Lost to Red Sox (46-41), 3-1 | Municipal Stadium (22-24) | 32-53 | |
| » Starters: Tom Brewer vs Tom Gorman | Seventh | 25 out |
| Friday, July 19 |
| » Lost to Orioles (42-44), 4-2 | Municipal Stadium (22-25) | 32-54 | Lost 2 |
| » Starters: Billy Loes vs Ned Garver | Seventh | 26 out |
| Saturday, July 20 |
| » Defeated Orioles (42-45), 6-5 | Municipal Stadium (23-25) | 33-54 | |
| » Starters: Connie Johnson vs Arnie Portocarrero | Seventh | 25 out |
| Sunday, July 21 |
| » Lost to Orioles (43-45), 7-2 | Municipal Stadium (23-26) | 33-55 | |
| » Starters: Hal Brown vs Wally Burnette | Seventh | 25 out |
| » Defeated Orioles (43-46), 3-2 | Municipal Stadium (24-26) | 34-55 | |
| » Starters: Ray Moore vs Alex Kellner | Seventh | 25 out |
| Tuesday, July 23 |
| » Lost to Red Sox (48-43), 1-0 | Fenway Park (1-6) | 34-56 | |
| » Starters: Virgil Trucks vs Frank Sullivan | Seventh | 26 out |
| Wednesday, July 24 |
| » Lost to Red Sox (49-43), 6-5 | Fenway Park (1-7) | 34-57 | Lost 2 |
| » Starters: Ralph Terry vs Tom Brewer | Seventh | 26 out |
| Thursday, July 25 |
| » Lost to Red Sox (50-43), 5-3 | Fenway Park (1-8) | 34-58 | Lost 3 |
| » Starters: Tom Gorman vs Bob Porterfield | Seventh | 26 out |
| Friday, July 26 |
| » Lost to Senators (34-62), 3-2 | Griffith Stadium (3-3) | 34-59 | Lost 4 |
| » Starters: Arnie Portocarrero vs Pedro Ramos | Seventh | 26 out |
| Saturday, July 27 |
| » Lost to Senators (35-62), 6-5 | Griffith Stadium (3-4) | 34-60 | Lost 5 |
| » Starters: Ned Garver vs Tex Clevenger | Seventh | 27 out |
| Sunday, July 28 |
| » Defeated Senators (35-63), 6-2 | Griffith Stadium (4-4) | 35-60 | |
| » Starters: Alex Kellner vs Chuck Stobbs | Sixth | 26 out |
| » Defeated Senators (35-64), 3-2 | Griffith Stadium (5-4) | 36-60 | Won 2 |
| » Starters: Ralph Terry vs Camilo Pascual | Sixth | 26 out |
| Tuesday, July 30 |
| » Lost to Yankees (63-34), 10-4 | Yankee Stadium (0-7) | 36-61 | |
| » Starters: Rip Coleman vs Whitey Ford | Seventh | 27 out |
| Wednesday, July 31 |
| » Lost to Yankees (64-34), 2-0 | Yankee Stadium (0-8) | 36-62 | Lost 2 |
| » Starters: Virgil Trucks vs Bob Turley | Seventh | 29 out |
| » Lost to Yankees (65-34), 5-4 | Yankee Stadium (0-9) | 36-63 | Lost 3 |
| » Starters: Arnie Portocarrero vs Don Larsen | Seventh | 29 out |
| Friday, August 2 |
| » Lost to Orioles (47-53), 5-4 | Memorial Stadium (0-5) | 36-64 | Lost 4 |
| » Starters: Alex Kellner vs Jerry Walker | Seventh | 30½ out |
| » Lost to Orioles (48-53), 10-2 | Memorial Stadium (0-6) | 36-65 | Lost 5 |
| » Starters: Ned Garver vs Connie Johnson | Seventh | 30½ out |
| Saturday, August 3 |
| » Lost to Orioles (49-53), 7-6 | Memorial Stadium (0-7) | 36-66 | Lost 6 |
| » Starters: Ralph Terry vs Hal Brown | Seventh | 31½ out |
| Sunday, August 4 |
| » Lost to Orioles (50-53), 5-0 | Memorial Stadium (0-8) | 36-67 | Lost 7 |
| » Starters: Arnie Portocarrero vs Billy Loes | Seventh | 33 out |
| Tuesday, August 6 |
| » Defeated White Sox (62-41), 3-2 | Comiskey Park I (2-4) | 37-67 | |
| » Manager: Harry Craft |
| » Starters: Alex Kellner vs Bob Keegan | Eighth | 32½ out |
| Wednesday, August 7 |
| » Lost to White Sox (63-41), 7-0 | Comiskey Park I (2-5) | 37-68 | |
| » Starters: Mickey McDermott vs Jim Wilson | Eighth | 32½ out |
| Thursday, August 8 |
| » Lost to White Sox (64-41), 7-4 | Comiskey Park I (2-6) | 37-69 | Lost 2 |
| » Starters: Rip Coleman vs Billy Pierce | Eighth | 32½ out |
| Friday, August 9 |
| » Defeated Indians (53-55), 3-2 | Cleveland Stadium (3-3) | 38-69 | |
| » Starters: Ralph Terry vs Early Wynn | Eighth | 31½ out |
| Saturday, August 10 |
| » Defeated Indians (53-56), 8-5 | Cleveland Stadium (4-3) | 39-69 | Won 2 |
| » Starters: Jack Urban vs Mike Garcia | Eighth | 31½ out |
| Sunday, August 11 |
| » Defeated Indians (53-57), 7-0 | Cleveland Stadium (5-3) | 40-69 | Won 3 |
| » Starters: Ned Garver vs Bud Daley | Seventh | 31 out |
| » Defeated Indians (53-58), 9-8 | Cleveland Stadium (6-3) | 41-69 | Won 4 |
| » Starters: Alex Kellner vs Don Mossi | Seventh | 31 out |
| Tuesday, August 13 |
| » Lost to Tigers (54-56), 3-1 | Municipal Stadium (24-27) | 41-70 | |
| » Starters: Paul Foytack vs Arnie Portocarrero | Seventh | 31½ out |
| » Defeated Tigers (54-57), 3-2 | Municipal Stadium (25-27) | 42-70 | |
| » Starters: Duke Maas vs Tom Gorman | Seventh | 31½ out |
| Wednesday, August 14 |
| » Lost to Tigers (55-57), 7-4 | Municipal Stadium (25-28) | 42-71 | |
| » Starters: Frank Lary vs Ralph Terry | Seventh | 31½ out |
| Thursday, August 15 |
| » Defeated Tigers (55-58), 7-2 | Municipal Stadium (26-28) | 43-71 | |
| » Starters: Jim Bunning vs Jack Urban | Seventh | 31½ out |
| Friday, August 16 |
| » Lost to Indians (55-60), 4-2 | Municipal Stadium (26-29) | 43-72 | |
| » Starters: Mike Garcia vs Alex Kellner | Seventh | 31½ out |
| Saturday, August 17 |
| » Defeated Indians (55-61), 4-3 | Municipal Stadium (27-29) | 44-72 | |
| » Starters: Early Wynn vs Ned Garver | Seventh | 31½ out |
| Sunday, August 18 |
| » Lost to Indians (56-61), 9-2 | Municipal Stadium (27-30) | 44-73 | |
| » Starters: Cal McLish vs Arnie Portocarrero | Eighth | 33 out |
| Monday, August 19 |
| » Defeated Indians (56-62), 1-0 | Municipal Stadium (28-30) | 45-73 | |
| » Starters: Ray Narleski vs Tom Gorman | Eighth | 32½ out |
| Tuesday, August 20 |
| » Defeated Yankees (77-41), 1-0 | Municipal Stadium (29-30) | 46-73 | Won 2 |
| » Starters: Bob Turley vs Ralph Terry | Seventh | 31½ out |
| Wednesday, August 21 |
| » Defeated Yankees (77-42), 6-3 | Municipal Stadium (30-30) | 47-73 | Won 3 |
| » Starters: Johnny Kucks vs Jack Urban | Seventh | 30½ out |
| Thursday, August 22 |
| » Lost to Yankees (78-42), 11-4 | Municipal Stadium (30-31) | 47-74 | |
| » Starters: Don Larsen vs Wally Burnette | Seventh | 31½ out |
| Friday, August 23 |
| » Lost to Orioles (58-61), 2-1 | Municipal Stadium (30-32) | 47-75 | Lost 2 |
| » Starters: Connie Johnson vs Alex Kellner | Seventh | 31½ out |
| Saturday, August 24 |
| » Lost to Orioles (59-61), 4-2 | Municipal Stadium (30-33) | 47-76 | Lost 3 |
| » Starters: Ken Lehman vs Ned Garver | Eighth | 32½ out |
| Sunday, August 25 |
| » Defeated Red Sox (63-59), 3-2 | Municipal Stadium (31-33) | 48-76 | |
| » Starters: Tom Brewer vs Tom Gorman | Seventh | 31½ out |
| Monday, August 26 |
| » Lost to Red Sox (64-59), 16-0 | Municipal Stadium (31-34) | 48-77 | |
| » Starters: Willard Nixon vs Ralph Terry | Seventh | 31½ out |
| Tuesday, August 27 |
| » Defeated Senators (47-78), 3-1 | Municipal Stadium (32-34) | 49-77 | |
| » Starters: Camilo Pascual vs Jack Urban | Seventh | 31½ out |
| Wednesday, August 28 |
| » Lost to Senators (48-78), 3-2 | Municipal Stadium (32-35) | 49-78 | |
| » Starters: Pedro Ramos vs Ralph Terry | Seventh | 32½ out |
| Friday, August 30 |
| » Defeated White Sox (75-52), 3-1 | Municipal Stadium (33-35) | 50-78 | |
| » Starters: Bob Keegan vs Alex Kellner | Seventh | 32 out |
| Saturday, August 31 |
| » Lost to White Sox (76-52), 8-3 | Municipal Stadium (33-36) | 50-79 | |
| » Starters: Jim Wilson vs Tom Gorman | Eighth | 32 out |
| Future Athletic Tom Candiotti is born in Walnut Creek, CA. |
| Sunday, September 1 |
| » Lost to White Sox (77-52), 5-0 | Municipal Stadium (33-37) | 50-80 | Lost 2 |
| » Starters: Bill Fischer vs Jack Urban | Eighth | 33 out |
| Monday, September 2 |
| » Lost to Indians (64-68), 8-0 | Cleveland Stadium (6-4) | 50-81 | Lost 3 |
| » Starters: Ned Garver vs Mike Garcia | Eighth | 33 out |
| » Lost to Indians (65-68), 6-3 | Cleveland Stadium (6-5) | 50-82 | Lost 4 |
| » Starters: Ralph Terry vs Vito Valentinetti | Eighth | 33 out |
| Friday, September 6 |
| » Lost to White Sox (79-54), 4-3 | Comiskey Park I (2-7) | 50-83 | Lost 5 |
| » Starters: Alex Kellner vs Jim Wilson | Seventh | 33½ out |
| Saturday, September 7 |
| » Lost to White Sox (80-54), 8-2 | Comiskey Park I (2-8) | 50-84 | Lost 6 |
| » Starters: Arnie Portocarrero vs Billy Pierce | Eighth | 34½ out |
| Sunday, September 8 |
| » Defeated White Sox (80-55), 3-2 | Comiskey Park I (3-8) | 51-84 | |
| » Starters: Jack Urban vs Dick Donovan | Eighth | 34½ out |
| Tuesday, September 10 |
| » Major-league debuts: Barry Latman (White Sox) |
| Wednesday, September 11 |
| » Defeated Orioles (65-72), 7-3 | Memorial Stadium (1-8) | 52-84 | Won 2 |
| » Starters: Ralph Terry vs Ray Moore | Seventh | 34½ out |
| » Lost to Orioles (66-72), 6-2 | Memorial Stadium (1-9) | 52-85 | |
| » Starters: Tom Gorman vs Jerry Walker | Seventh | 34½ out |
| Friday, September 13 |
| » Lost to Senators (53-87), 11-6 | Griffith Stadium (5-5) | 52-86 | Lost 2 |
| » Starters: Alex Kellner vs Russ Kemmerer | Eighth | 35½ out |
| Saturday, September 14 |
| » Lost to Senators (54-87), 3-2 | Griffith Stadium (5-6) | 52-87 | Lost 3 |
| » Starters: Ned Garver vs Ralph Lumenti | Eighth | 35½ out |
| Sunday, September 15 |
| » Lost to Yankees (90-53), 5-3 | Yankee Stadium (0-10) | 52-88 | Lost 4 |
| » Starters: Jack Urban vs Bob Turley | Eighth | 37½ out |
| » Lost to Yankees (91-53), 3-0 | Yankee Stadium (0-11) | 52-89 | Lost 5 |
| » Starters: George Brunet vs Don Larsen | Eighth | 37½ out |
| Tuesday, September 17 |
| » Lost to Red Sox (77-67), 9-8 | Fenway Park (1-9) | 52-90 | Lost 6 |
| » Starters: Ralph Terry vs Mike Fornieles | Eighth | 38½ out |
| » Major-league debuts: Harry Taylor (Athletics) |
| Wednesday, September 18 |
| » Defeated Red Sox (77-68), 2-1 | Fenway Park (2-9) | 53-90 | |
| » Starters: Tom Gorman vs Frank Sullivan | Seventh | 38½ out |
| Saturday, September 21 |
| » Defeated Tigers (75-71), 6-3 | Municipal Stadium (34-37) | 54-90 | Won 2 |
| » Starters: Jim Bunning vs Jack Urban | Sixth | 38 out |
| Sunday, September 22 |
| » Defeated Tigers (75-72), 4-3 | Municipal Stadium (35-37) | 55-90 | Won 3 |
| » Starters: Paul Foytack vs Ralph Terry | Seventh | 37½ out |
| » Defeated Tigers (75-73), 2-1 | Municipal Stadium (36-37) | 56-90 | Won 4 |
| » Starters: Duke Maas vs Ned Garver | Seventh | 37½ out |
| Monday, September 23 |
| » Defeated White Sox (88-60), 6-5 | Municipal Stadium (37-37) | 57-90 | Won 5 |
| » Starters: Bob Keegan vs Alex Kellner | Seventh | 37 out |
| Tuesday, September 24 |
| » Lost to White Sox (89-60), 7-6 | Municipal Stadium (37-38) | 57-91 | |
| » Starters: Bill Fischer vs George Brunet | Seventh | 37½ out |
| Wednesday, September 25 |
| » Lost to Indians (73-76), 9-7 | Municipal Stadium (37-39) | 57-92 | Lost 2 |
| » Starters: Ray Narleski vs Tom Gorman | Sixth | 38 out |
| Thursday, September 26 |
| » Lost to Indians (74-76), 2-1 | Municipal Stadium (37-40) | 57-93 | Lost 3 |
| » Starters: Vito Valentinetti vs Ralph Terry | Seventh | 38½ out |
| Friday, September 27 |
| » Defeated Tigers (77-75), 9-7 | Tiger Stadium (4-5) | 58-93 | |
| » Starters: Jack Urban vs Jim Bunning | Seventh | 38½ out |
| Saturday, September 28 |
| » Defeated Tigers (77-76), 5-3 | Tiger Stadium (5-5) | 59-93 | Won 2 |
| » Starters: Arnie Portocarrero vs Frank Lary | Seventh | 38½ out |
| Sunday, September 29 |
| » Lost to Tigers (78-76), 7-4 | Tiger Stadium (5-6) | 59-94 | |
| » Starters: Tom Gorman vs Duke Maas | Seventh | 38½ out |
| Sunday, October 6 |
| Future Athletic Alfredo Griffin is born in Santo Domingo, D.R. |
Game information provided by Retrosheet (www.retrosheet.org) |